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Search of human proteins with 94721241
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|94721241 isoleucine tRNA synthetase [Homo sapiens]
(1262 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|94721239 isoleucine tRNA synthetase [Homo sapiens] 2554 0.0
gi|94721241 isoleucine tRNA synthetase [Homo sapiens] 2554 0.0
gi|46852147 mitochondrial isoleucine tRNA synthetase [Homo sapiens] 282 1e-75
gi|5454158 valyl-tRNA synthetase [Homo sapiens] 149 2e-35
gi|55741845 valyl-tRNA synthetase 2, mitochondrial [Homo sapiens] 122 2e-27
gi|7661872 leucyl-tRNA synthetase 2, mitochondrial precursor [Ho... 65 4e-10
gi|108773810 leucyl-tRNA synthetase [Homo sapiens] 40 0.014
gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens] 37 0.12
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H... 36 0.20
gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta ... 35 0.35
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 35 0.45
gi|38569430 activating transcription factor 7 interacting protei... 35 0.59
gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens] 34 0.77
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [... 34 0.77
gi|28269672 serologically defined colon cancer antigen 8 [Homo s... 34 0.77
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo... 33 1.7
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo... 33 1.7
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo... 32 2.9
gi|139394579 zinc finger and BTB domain containing 40 [Homo sapi... 32 2.9
gi|139394556 zinc finger and BTB domain containing 40 [Homo sapi... 32 2.9
gi|221219020 NYD-SP11 protein [Homo sapiens] 32 3.8
gi|156104874 envoplakin [Homo sapiens] 32 3.8
gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo ... 32 3.8
gi|148806872 lupus brain antigen 1 [Homo sapiens] 32 3.8
gi|114326455 chromodomain helicase DNA binding protein 8 [Homo s... 32 5.0
gi|21359963 ring finger and WD repeat domain 2 isoform a [Homo s... 31 6.5
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s... 31 8.5
gi|14043022 methionyl-tRNA synthetase [Homo sapiens] 31 8.5
gi|24308436 methionine-tRNA synthetase 2 precursor [Homo sapiens] 31 8.5
>gi|94721239 isoleucine tRNA synthetase [Homo sapiens]
Length = 1262
Score = 2554 bits (6619), Expect = 0.0
Identities = 1262/1262 (100%), Positives = 1262/1262 (100%)
Query: 1 MLQQVPENINFPAEEEKILEFWTEFNCFQECLKQSKHKPKFTFYDGPPFATGLPHYGHIL 60
MLQQVPENINFPAEEEKILEFWTEFNCFQECLKQSKHKPKFTFYDGPPFATGLPHYGHIL
Sbjct: 1 MLQQVPENINFPAEEEKILEFWTEFNCFQECLKQSKHKPKFTFYDGPPFATGLPHYGHIL 60
Query: 61 AGTIKDIVTRYAHQSGFHVDRRFGWDCHGLPVEYEIDKTLGIRGPEDVAKMGITEYNNQC 120
AGTIKDIVTRYAHQSGFHVDRRFGWDCHGLPVEYEIDKTLGIRGPEDVAKMGITEYNNQC
Sbjct: 61 AGTIKDIVTRYAHQSGFHVDRRFGWDCHGLPVEYEIDKTLGIRGPEDVAKMGITEYNNQC 120
Query: 121 RAIVMRYSAEWKSTVSRLGRWIDFDNDYKTLYPQFMESVWWVFKQLYDKGLVYRGVKVMP 180
RAIVMRYSAEWKSTVSRLGRWIDFDNDYKTLYPQFMESVWWVFKQLYDKGLVYRGVKVMP
Sbjct: 121 RAIVMRYSAEWKSTVSRLGRWIDFDNDYKTLYPQFMESVWWVFKQLYDKGLVYRGVKVMP 180
Query: 181 FSTACNTPLSNFESHQNYKDVQDPSVFVTFPLEEDETVSLVAWTTTPWTLPSNLAVCVNP 240
FSTACNTPLSNFESHQNYKDVQDPSVFVTFPLEEDETVSLVAWTTTPWTLPSNLAVCVNP
Sbjct: 181 FSTACNTPLSNFESHQNYKDVQDPSVFVTFPLEEDETVSLVAWTTTPWTLPSNLAVCVNP 240
Query: 241 EMQYVKIKDVARGRLLILMEARLSALYKLESDYEILERFPGAYLKGKKYRPLFDYFLKCK 300
EMQYVKIKDVARGRLLILMEARLSALYKLESDYEILERFPGAYLKGKKYRPLFDYFLKCK
Sbjct: 241 EMQYVKIKDVARGRLLILMEARLSALYKLESDYEILERFPGAYLKGKKYRPLFDYFLKCK 300
Query: 301 ENGAFTVLVDNYVKEEEGTGVVHQAPYFGAEDYRVCMDFNIIRKDSLPVCPVDASGCFTT 360
ENGAFTVLVDNYVKEEEGTGVVHQAPYFGAEDYRVCMDFNIIRKDSLPVCPVDASGCFTT
Sbjct: 301 ENGAFTVLVDNYVKEEEGTGVVHQAPYFGAEDYRVCMDFNIIRKDSLPVCPVDASGCFTT 360
Query: 361 EVTDFAGQYVKDADKSIIRTLKEQGRLLVATTFTHSYPFCWRSDTPLIYKAVPSWFVRVE 420
EVTDFAGQYVKDADKSIIRTLKEQGRLLVATTFTHSYPFCWRSDTPLIYKAVPSWFVRVE
Sbjct: 361 EVTDFAGQYVKDADKSIIRTLKEQGRLLVATTFTHSYPFCWRSDTPLIYKAVPSWFVRVE 420
Query: 421 NMVDQLLRNNDLCYWVPELVREKRFGNWLKDARDWTISRNRYWGTPIPLWVSDDFEEVVC 480
NMVDQLLRNNDLCYWVPELVREKRFGNWLKDARDWTISRNRYWGTPIPLWVSDDFEEVVC
Sbjct: 421 NMVDQLLRNNDLCYWVPELVREKRFGNWLKDARDWTISRNRYWGTPIPLWVSDDFEEVVC 480
Query: 481 IGSVAELEELSGAKISDLHRESVDHLTIPSRCGKGSLHRISEVFDCWFESGSMPYAQVHY 540
IGSVAELEELSGAKISDLHRESVDHLTIPSRCGKGSLHRISEVFDCWFESGSMPYAQVHY
Sbjct: 481 IGSVAELEELSGAKISDLHRESVDHLTIPSRCGKGSLHRISEVFDCWFESGSMPYAQVHY 540
Query: 541 PFENKREFEDAFPADFIAEGIDQTRGWFYTLLVLATALFGQPPFKNVIVNGLVLASDGQK 600
PFENKREFEDAFPADFIAEGIDQTRGWFYTLLVLATALFGQPPFKNVIVNGLVLASDGQK
Sbjct: 541 PFENKREFEDAFPADFIAEGIDQTRGWFYTLLVLATALFGQPPFKNVIVNGLVLASDGQK 600
Query: 601 MSKRKKNYPDPVSIIQKYGADALRLYLINSPVVRAENLRFKEEGVRDVLKDVLLPWYNAY 660
MSKRKKNYPDPVSIIQKYGADALRLYLINSPVVRAENLRFKEEGVRDVLKDVLLPWYNAY
Sbjct: 601 MSKRKKNYPDPVSIIQKYGADALRLYLINSPVVRAENLRFKEEGVRDVLKDVLLPWYNAY 660
Query: 661 RFLIQNVLRLQKEEEIEFLYNENTVRESPNITDRWILSFMQSLIGFFETEMAAYRLYTVV 720
RFLIQNVLRLQKEEEIEFLYNENTVRESPNITDRWILSFMQSLIGFFETEMAAYRLYTVV
Sbjct: 661 RFLIQNVLRLQKEEEIEFLYNENTVRESPNITDRWILSFMQSLIGFFETEMAAYRLYTVV 720
Query: 721 PRLVKFVDILTNWYVRMNRRRLKGENGMEDCVMALETLFSVLLSLCRLMAPYTPFLTELM 780
PRLVKFVDILTNWYVRMNRRRLKGENGMEDCVMALETLFSVLLSLCRLMAPYTPFLTELM
Sbjct: 721 PRLVKFVDILTNWYVRMNRRRLKGENGMEDCVMALETLFSVLLSLCRLMAPYTPFLTELM 780
Query: 781 YQNLKVLIDPVSVQDKDTLSIHYLMLPRVREELIDKKTESAVSQMQSVIELGRVIRDRKT 840
YQNLKVLIDPVSVQDKDTLSIHYLMLPRVREELIDKKTESAVSQMQSVIELGRVIRDRKT
Sbjct: 781 YQNLKVLIDPVSVQDKDTLSIHYLMLPRVREELIDKKTESAVSQMQSVIELGRVIRDRKT 840
Query: 841 IPIKYPLKEIVVIHQDPEALKDIKSLEKYIIEELNVRKVTLSTDKNKYGIRLRAEPDHMV 900
IPIKYPLKEIVVIHQDPEALKDIKSLEKYIIEELNVRKVTLSTDKNKYGIRLRAEPDHMV
Sbjct: 841 IPIKYPLKEIVVIHQDPEALKDIKSLEKYIIEELNVRKVTLSTDKNKYGIRLRAEPDHMV 900
Query: 901 LGKRLKGAFKAVMTSIKQLSSEELEQFQKTGTIVVEGHELHDEDIRLMYTFDQATGGTAQ 960
LGKRLKGAFKAVMTSIKQLSSEELEQFQKTGTIVVEGHELHDEDIRLMYTFDQATGGTAQ
Sbjct: 901 LGKRLKGAFKAVMTSIKQLSSEELEQFQKTGTIVVEGHELHDEDIRLMYTFDQATGGTAQ 960
Query: 961 FEAHSDAQALVLLDVTPDQSMVDEGMAREVINRIQKLRKKCNLVPTDEITVYYKAKSEGT 1020
FEAHSDAQALVLLDVTPDQSMVDEGMAREVINRIQKLRKKCNLVPTDEITVYYKAKSEGT
Sbjct: 961 FEAHSDAQALVLLDVTPDQSMVDEGMAREVINRIQKLRKKCNLVPTDEITVYYKAKSEGT 1020
Query: 1021 YLNSVIESHTEFIFTTIKAPLKPYPVSPSDKVLIQEKTQLKGSELEITLTRGSSLPGPAC 1080
YLNSVIESHTEFIFTTIKAPLKPYPVSPSDKVLIQEKTQLKGSELEITLTRGSSLPGPAC
Sbjct: 1021 YLNSVIESHTEFIFTTIKAPLKPYPVSPSDKVLIQEKTQLKGSELEITLTRGSSLPGPAC 1080
Query: 1081 AYVNLNICANGSEQGGVLLLENPKGDNRLDLLKLKSVVTSIFGVKNTELAVFHDETEIQN 1140
AYVNLNICANGSEQGGVLLLENPKGDNRLDLLKLKSVVTSIFGVKNTELAVFHDETEIQN
Sbjct: 1081 AYVNLNICANGSEQGGVLLLENPKGDNRLDLLKLKSVVTSIFGVKNTELAVFHDETEIQN 1140
Query: 1141 QTDLLSLSGKTLCVTAGSAPSLINSSSTLLCQYINLQLLNAKPQECLMGTVGTLLLENPL 1200
QTDLLSLSGKTLCVTAGSAPSLINSSSTLLCQYINLQLLNAKPQECLMGTVGTLLLENPL
Sbjct: 1141 QTDLLSLSGKTLCVTAGSAPSLINSSSTLLCQYINLQLLNAKPQECLMGTVGTLLLENPL 1200
Query: 1201 GQNGLTHQGLLYEAAKVFGLRSRKLKLFLNETQTQEITEDIPVKTLNMKTVYVSVLPTTA 1260
GQNGLTHQGLLYEAAKVFGLRSRKLKLFLNETQTQEITEDIPVKTLNMKTVYVSVLPTTA
Sbjct: 1201 GQNGLTHQGLLYEAAKVFGLRSRKLKLFLNETQTQEITEDIPVKTLNMKTVYVSVLPTTA 1260
Query: 1261 DF 1262
DF
Sbjct: 1261 DF 1262
>gi|94721241 isoleucine tRNA synthetase [Homo sapiens]
Length = 1262
Score = 2554 bits (6619), Expect = 0.0
Identities = 1262/1262 (100%), Positives = 1262/1262 (100%)
Query: 1 MLQQVPENINFPAEEEKILEFWTEFNCFQECLKQSKHKPKFTFYDGPPFATGLPHYGHIL 60
MLQQVPENINFPAEEEKILEFWTEFNCFQECLKQSKHKPKFTFYDGPPFATGLPHYGHIL
Sbjct: 1 MLQQVPENINFPAEEEKILEFWTEFNCFQECLKQSKHKPKFTFYDGPPFATGLPHYGHIL 60
Query: 61 AGTIKDIVTRYAHQSGFHVDRRFGWDCHGLPVEYEIDKTLGIRGPEDVAKMGITEYNNQC 120
AGTIKDIVTRYAHQSGFHVDRRFGWDCHGLPVEYEIDKTLGIRGPEDVAKMGITEYNNQC
Sbjct: 61 AGTIKDIVTRYAHQSGFHVDRRFGWDCHGLPVEYEIDKTLGIRGPEDVAKMGITEYNNQC 120
Query: 121 RAIVMRYSAEWKSTVSRLGRWIDFDNDYKTLYPQFMESVWWVFKQLYDKGLVYRGVKVMP 180
RAIVMRYSAEWKSTVSRLGRWIDFDNDYKTLYPQFMESVWWVFKQLYDKGLVYRGVKVMP
Sbjct: 121 RAIVMRYSAEWKSTVSRLGRWIDFDNDYKTLYPQFMESVWWVFKQLYDKGLVYRGVKVMP 180
Query: 181 FSTACNTPLSNFESHQNYKDVQDPSVFVTFPLEEDETVSLVAWTTTPWTLPSNLAVCVNP 240
FSTACNTPLSNFESHQNYKDVQDPSVFVTFPLEEDETVSLVAWTTTPWTLPSNLAVCVNP
Sbjct: 181 FSTACNTPLSNFESHQNYKDVQDPSVFVTFPLEEDETVSLVAWTTTPWTLPSNLAVCVNP 240
Query: 241 EMQYVKIKDVARGRLLILMEARLSALYKLESDYEILERFPGAYLKGKKYRPLFDYFLKCK 300
EMQYVKIKDVARGRLLILMEARLSALYKLESDYEILERFPGAYLKGKKYRPLFDYFLKCK
Sbjct: 241 EMQYVKIKDVARGRLLILMEARLSALYKLESDYEILERFPGAYLKGKKYRPLFDYFLKCK 300
Query: 301 ENGAFTVLVDNYVKEEEGTGVVHQAPYFGAEDYRVCMDFNIIRKDSLPVCPVDASGCFTT 360
ENGAFTVLVDNYVKEEEGTGVVHQAPYFGAEDYRVCMDFNIIRKDSLPVCPVDASGCFTT
Sbjct: 301 ENGAFTVLVDNYVKEEEGTGVVHQAPYFGAEDYRVCMDFNIIRKDSLPVCPVDASGCFTT 360
Query: 361 EVTDFAGQYVKDADKSIIRTLKEQGRLLVATTFTHSYPFCWRSDTPLIYKAVPSWFVRVE 420
EVTDFAGQYVKDADKSIIRTLKEQGRLLVATTFTHSYPFCWRSDTPLIYKAVPSWFVRVE
Sbjct: 361 EVTDFAGQYVKDADKSIIRTLKEQGRLLVATTFTHSYPFCWRSDTPLIYKAVPSWFVRVE 420
Query: 421 NMVDQLLRNNDLCYWVPELVREKRFGNWLKDARDWTISRNRYWGTPIPLWVSDDFEEVVC 480
NMVDQLLRNNDLCYWVPELVREKRFGNWLKDARDWTISRNRYWGTPIPLWVSDDFEEVVC
Sbjct: 421 NMVDQLLRNNDLCYWVPELVREKRFGNWLKDARDWTISRNRYWGTPIPLWVSDDFEEVVC 480
Query: 481 IGSVAELEELSGAKISDLHRESVDHLTIPSRCGKGSLHRISEVFDCWFESGSMPYAQVHY 540
IGSVAELEELSGAKISDLHRESVDHLTIPSRCGKGSLHRISEVFDCWFESGSMPYAQVHY
Sbjct: 481 IGSVAELEELSGAKISDLHRESVDHLTIPSRCGKGSLHRISEVFDCWFESGSMPYAQVHY 540
Query: 541 PFENKREFEDAFPADFIAEGIDQTRGWFYTLLVLATALFGQPPFKNVIVNGLVLASDGQK 600
PFENKREFEDAFPADFIAEGIDQTRGWFYTLLVLATALFGQPPFKNVIVNGLVLASDGQK
Sbjct: 541 PFENKREFEDAFPADFIAEGIDQTRGWFYTLLVLATALFGQPPFKNVIVNGLVLASDGQK 600
Query: 601 MSKRKKNYPDPVSIIQKYGADALRLYLINSPVVRAENLRFKEEGVRDVLKDVLLPWYNAY 660
MSKRKKNYPDPVSIIQKYGADALRLYLINSPVVRAENLRFKEEGVRDVLKDVLLPWYNAY
Sbjct: 601 MSKRKKNYPDPVSIIQKYGADALRLYLINSPVVRAENLRFKEEGVRDVLKDVLLPWYNAY 660
Query: 661 RFLIQNVLRLQKEEEIEFLYNENTVRESPNITDRWILSFMQSLIGFFETEMAAYRLYTVV 720
RFLIQNVLRLQKEEEIEFLYNENTVRESPNITDRWILSFMQSLIGFFETEMAAYRLYTVV
Sbjct: 661 RFLIQNVLRLQKEEEIEFLYNENTVRESPNITDRWILSFMQSLIGFFETEMAAYRLYTVV 720
Query: 721 PRLVKFVDILTNWYVRMNRRRLKGENGMEDCVMALETLFSVLLSLCRLMAPYTPFLTELM 780
PRLVKFVDILTNWYVRMNRRRLKGENGMEDCVMALETLFSVLLSLCRLMAPYTPFLTELM
Sbjct: 721 PRLVKFVDILTNWYVRMNRRRLKGENGMEDCVMALETLFSVLLSLCRLMAPYTPFLTELM 780
Query: 781 YQNLKVLIDPVSVQDKDTLSIHYLMLPRVREELIDKKTESAVSQMQSVIELGRVIRDRKT 840
YQNLKVLIDPVSVQDKDTLSIHYLMLPRVREELIDKKTESAVSQMQSVIELGRVIRDRKT
Sbjct: 781 YQNLKVLIDPVSVQDKDTLSIHYLMLPRVREELIDKKTESAVSQMQSVIELGRVIRDRKT 840
Query: 841 IPIKYPLKEIVVIHQDPEALKDIKSLEKYIIEELNVRKVTLSTDKNKYGIRLRAEPDHMV 900
IPIKYPLKEIVVIHQDPEALKDIKSLEKYIIEELNVRKVTLSTDKNKYGIRLRAEPDHMV
Sbjct: 841 IPIKYPLKEIVVIHQDPEALKDIKSLEKYIIEELNVRKVTLSTDKNKYGIRLRAEPDHMV 900
Query: 901 LGKRLKGAFKAVMTSIKQLSSEELEQFQKTGTIVVEGHELHDEDIRLMYTFDQATGGTAQ 960
LGKRLKGAFKAVMTSIKQLSSEELEQFQKTGTIVVEGHELHDEDIRLMYTFDQATGGTAQ
Sbjct: 901 LGKRLKGAFKAVMTSIKQLSSEELEQFQKTGTIVVEGHELHDEDIRLMYTFDQATGGTAQ 960
Query: 961 FEAHSDAQALVLLDVTPDQSMVDEGMAREVINRIQKLRKKCNLVPTDEITVYYKAKSEGT 1020
FEAHSDAQALVLLDVTPDQSMVDEGMAREVINRIQKLRKKCNLVPTDEITVYYKAKSEGT
Sbjct: 961 FEAHSDAQALVLLDVTPDQSMVDEGMAREVINRIQKLRKKCNLVPTDEITVYYKAKSEGT 1020
Query: 1021 YLNSVIESHTEFIFTTIKAPLKPYPVSPSDKVLIQEKTQLKGSELEITLTRGSSLPGPAC 1080
YLNSVIESHTEFIFTTIKAPLKPYPVSPSDKVLIQEKTQLKGSELEITLTRGSSLPGPAC
Sbjct: 1021 YLNSVIESHTEFIFTTIKAPLKPYPVSPSDKVLIQEKTQLKGSELEITLTRGSSLPGPAC 1080
Query: 1081 AYVNLNICANGSEQGGVLLLENPKGDNRLDLLKLKSVVTSIFGVKNTELAVFHDETEIQN 1140
AYVNLNICANGSEQGGVLLLENPKGDNRLDLLKLKSVVTSIFGVKNTELAVFHDETEIQN
Sbjct: 1081 AYVNLNICANGSEQGGVLLLENPKGDNRLDLLKLKSVVTSIFGVKNTELAVFHDETEIQN 1140
Query: 1141 QTDLLSLSGKTLCVTAGSAPSLINSSSTLLCQYINLQLLNAKPQECLMGTVGTLLLENPL 1200
QTDLLSLSGKTLCVTAGSAPSLINSSSTLLCQYINLQLLNAKPQECLMGTVGTLLLENPL
Sbjct: 1141 QTDLLSLSGKTLCVTAGSAPSLINSSSTLLCQYINLQLLNAKPQECLMGTVGTLLLENPL 1200
Query: 1201 GQNGLTHQGLLYEAAKVFGLRSRKLKLFLNETQTQEITEDIPVKTLNMKTVYVSVLPTTA 1260
GQNGLTHQGLLYEAAKVFGLRSRKLKLFLNETQTQEITEDIPVKTLNMKTVYVSVLPTTA
Sbjct: 1201 GQNGLTHQGLLYEAAKVFGLRSRKLKLFLNETQTQEITEDIPVKTLNMKTVYVSVLPTTA 1260
Query: 1261 DF 1262
DF
Sbjct: 1261 DF 1262
>gi|46852147 mitochondrial isoleucine tRNA synthetase [Homo sapiens]
Length = 1012
Score = 282 bits (722), Expect = 1e-75
Identities = 252/878 (28%), Positives = 393/878 (44%), Gaps = 107/878 (12%)
Query: 33 KQSKHKPKFTFYDGPPFATGLPHYGHILAGTIKDIVTRYAHQSGFHVDRRFGWDCHGLPV 92
++ K K +F +DGPP+A G PH GH L +KDI R+ +G + GWDCHGLP+
Sbjct: 101 RERKVKTEFCLHDGPPYANGDPHVGHALNKILKDIANRFHMMNGSKIHFVPGWDCHGLPI 160
Query: 93 EYEIDKTLGIRGPEDVAKMGITEYNNQCRAIVMRYSAEWKSTVSRLGRWIDFDNDYKTLY 152
E ++ LG + + E + R+ + KS R G D++N Y T
Sbjct: 161 EIKVLSELG----REAQNLSAMEIRKKARSFAKAAIEKQKSAFIRWGIMADWNNCYYTFD 216
Query: 153 PQFMESVWWVFKQLYDKGLVYRGVKVMPFSTACNTPLSNFESHQNYKDVQDPSVFVTFPL 212
++ F Q+YDKGLVYR K + +S + T L+ E N + V S++V FPL
Sbjct: 217 GKYEAKQLRTFYQMYDKGLVYRSYKPVFWSPSSRTALAEAELEYNPEHV-SRSIYVKFPL 275
Query: 213 -----------EEDETVSLVAWTTTPWTLPSNLAVCVNPEMQYVKIKDVARGRLLILMEA 261
+ VS++ WTT PWT+P+N AVC PE +Y +K G L +L
Sbjct: 276 LKPSPKLASLIDGSSPVSILVWTTQPWTIPANEAVCYMPESKYAVVKCSKSGDLYVLAAD 335
Query: 262 RLSALYK-LESDYEILERFPGAYLK-GKKYRPLFDYFLKCKENGAFTVLVDNYVKEEEGT 319
+++++ LE+ +E + G L+ G PL + A +L N+V +GT
Sbjct: 336 KVASVASTLETTFETISTLSGVDLENGTCSHPLI-------PDKASPLLPANHVTMAKGT 388
Query: 320 GVVHQAPYFGAEDYRVCMDFNIIRKDSLPV-CPVDASGCFTTEVTDFAG------QYVKD 372
G+VH AP G EDY V N LP+ C VD G F TD AG +++
Sbjct: 389 GLVHTAPAHGMEDYGVASQHN------LPMDCLVDEDGVF----TDVAGPELQNKAVLEE 438
Query: 373 ADKSIIRTLKEQGRLLVATTFTHSYPFCWRSDTPLIYKAVPSWFVRVENMVDQLLRNNDL 432
+I+ L+ LL HSYP+ WR+ P++ +A WF+ + D+
Sbjct: 439 GTDVVIKMLQTAKNLLKEEKLVHSYPYDWRTKKPVVIRASKQWFINI----------TDI 488
Query: 433 CYWVPELVREKRF-----GNWLKDARD----WTISRNRYWGTPIPLWVSDDFEEVVCIGS 483
EL+++ +F N + + D W ISR R WG PIP++ +E +
Sbjct: 489 KTAAKELLKKVKFIPGSALNGMVEMMDRRPYWCISRQRVWGVPIPVFHHKTKDEYLINSQ 548
Query: 484 VAE-LEELSGAKISDLHRESVDHLTIPSRC-----GKGSLHRI--SEVFDCWFESG-SMP 534
E + +L SD+ +P G +L + ++ D WF+SG S
Sbjct: 549 TTEHIVKLVEQHGSDIWWTLPPEQLLPKEVLSEVGGPDALEYVPGQDILDIWFDSGTSWS 608
Query: 535 YAQVHYPFENKREFEDAFPADFIAEGIDQTRGWFYTLLVLATALFGQPPFKNVIVNGLVL 594
Y P ++R AD EG DQ GWF + L+ + A + P+K VIV+G L
Sbjct: 609 YV---LPGPDQR-------ADLYLEGKDQLGGWFQSSLLTSVAARKRAPYKTVIVHGFTL 658
Query: 595 ASDGQKMSKRKKN--YPDPV-------SIIQKYGADALRLYLINSPVVRAENLRFKEEGV 645
G+KMSK N +PD V S YGAD LR ++ +S V + V
Sbjct: 659 GEKGEKMSKSLGNVIHPDVVVNGGQDQSKEPPYGADVLRWWVADSNVFTEVAI---GPSV 715
Query: 646 RDVLKDVLLPWYNAYRFLIQNVLRLQKEEEIEFLYNENTVRESPNITDRWILSFMQSLIG 705
+ +D + N RFL+ NV E ++ + D+++L +Q L
Sbjct: 716 LNAARDDISKLRNTLRFLLGNVADFNPE-------TDSIPVNDMYVIDQYMLHLLQDLAN 768
Query: 706 FFETEMAAYRLYTVVPRLVK--FVDILTNWYVRMNRRRLKGENGMEDCVMALET-LFSVL 762
TE+ + V RL++ + L+N+Y + + RL E + + +T L +L
Sbjct: 769 KI-TELYKQYDFGKVVRLLRTFYTRELSNFYFSIIKDRLYCEKENDPKRRSCQTALVEIL 827
Query: 763 LSLCRLMAPYTPFLTELMYQNLKVLIDPVSVQDKDTLSIHYLMLPRVREELIDKKTESAV 822
+ R AP P L E ++Q++ + +P SV +S + EE ++
Sbjct: 828 DVIVRSFAPILPHLAEEVFQHIPYIKEPKSVFRTGWISTSSIWKKPGLEEAVESACAMRD 887
Query: 823 SQMQSVIELGRVIRDRKTIPIKYP--LKEIVVIHQDPE 858
S + S+ G+ + K I + P L EI+ + Q E
Sbjct: 888 SFLGSI--PGKNAAEYKVITVIEPGLLFEIIEMLQSEE 923
>gi|5454158 valyl-tRNA synthetase [Homo sapiens]
Length = 1264
Score = 149 bits (375), Expect = 2e-35
Identities = 185/796 (23%), Positives = 319/796 (40%), Gaps = 121/796 (15%)
Query: 47 PPFATGLPHYGHILAGTIKDIVTRYAHQSGFHVDRRFGWDCHGLPVEYEIDKTLGIRGPE 106
PP TG H GH L I+D +TR+ G G D G+ + ++K L
Sbjct: 343 PPNVTGSLHLGHALTNAIQDSLTRWHRMRGETTLWNPGCDHAGIATQVVVEKKLW----- 397
Query: 107 DVAKMGITEYNNQCRAIVMRYSAEWKST--------VSRLGRWIDFDNDYKTLYPQFMES 158
+ G++ + A + +WK + +LG +D+D T+ P+ +
Sbjct: 398 --REQGLSRHQLGREAFLQEVW-KWKEEKGDRIYHQLKKLGSSLDWDRACFTMDPKLSAA 454
Query: 159 VWWVFKQLYDKGLVYRGVKVMPFSTACNTPLSNFE------------SHQNYKDVQDPSV 206
V F +L+++G++YR +++ +S N+ +S+ E S YK+ + V
Sbjct: 455 VTEAFVRLHEEGIIYRSTRLVNWSCTLNSAISDIEVDKKELTGRTLLSVPGYKEKVEFGV 514
Query: 207 FVTFPLE---EDETVSLVAWTTTPWTLPSNLAVCVNPEMQYVKIKDVARGRLLILMEARL 263
V+F + D +V TT T+ ++AV V+P+
Sbjct: 515 LVSFAYKVQGSDSDEEVVVATTRIETMLGDVAVAVHPK---------------------- 552
Query: 264 SALYKLESDYEILERFPGAYLKGKKYRPLFDYFLKCKENGAFTVLVDNYVKEEEGTGVVH 323
++ Y+ +LKGK + FL + + ++ D +V + GTG V
Sbjct: 553 ------DTRYQ--------HLKGKN---VIHPFL----SRSLPIVFDEFVDMDFGTGAVK 591
Query: 324 QAPYFGAEDYRVCMDFNIIRKDSLPVCPVDASGCFTTEVTDFAGQYVKDADKSIIRTLKE 383
P DY V R + +D+ G F G +A K+++ LKE
Sbjct: 592 ITPAHDQNDYEVGQ-----RHGLEAISIMDSRGALINVPPPFLGLPRFEARKAVLVALKE 646
Query: 384 QGRLLVATTFTHSYPFCWRSDTPLIYKAVPSWFVRVENMVDQL---LRNNDLCYWVPELV 440
+G P C RS + P W+VR M + DL +PE
Sbjct: 647 RGLFRGIEDNPMVVPLCNRSKDVVEPLLRPQWYVRCGEMAQAASAAVTRGDLRI-LPE-A 704
Query: 441 REKRFGNWLKDARDWTISRNRYWGTPIPLWVSDDFEEVVCIGSVAELEE-LSGAKISDLH 499
++ + W+ + R+W ISR +WG IP + + V G + +SG ++
Sbjct: 705 HQRTWHAWMDNIREWCISRQLWWGHRIPAYFVTVSDPAVPPGEDPDGRYWVSGRNEAEAR 764
Query: 500 RESVDHLTIPSRCGKGSLHRISEVFDCWFESGSMPYAQVHYPFENKREFEDAFPADFIAE 559
++ + K SL + +V D WF SG P + + +P +++ + +P +
Sbjct: 765 EKAAKEFGVSP--DKISLQQDEDVLDTWFSSGLFPLSILGWPNQSE-DLSVFYPGTLLET 821
Query: 560 GIDQTRGWFYTLLVLATALFGQPPFKNVIVNGLVLASDGQKMSKRKKNYPDPVSIIQKYG 619
G D W +++L L G+ PF+ V ++ +V + G+KMSK N DP+ +I
Sbjct: 822 GHDILFFWVARMVMLGLKLTGRLPFREVYLHAIVRDAHGRKMSKSLGNVIDPLDVIYGIS 881
Query: 620 ADALRLYLINSPVVRAENLRFKE-----------EGVRDVLKDVLLPWYNAYRFLIQNVL 668
L L+NS + +E + KE E D L+ L + + R + +V
Sbjct: 882 LQGLHNQLLNSNLDPSEVEKAKEGQKADFPAGIPECGTDALRFGLCAYMSQGRDINLDVN 941
Query: 669 R-LQKEEEIEFLYNENTVR---------ESP--------NITDRWILSFMQSLIGFFETE 710
R L L+N SP ++ DRWI S + +
Sbjct: 942 RILGYRHFCNKLWNATKFALRGLGKGFVPSPTSQPGGHESLVDRWIRSRLTEAVRLSNQG 1001
Query: 711 MAAYRLYTVVPRLVKF-VDILTNWYVRMNRRRLKG-ENGMEDCVMALETLFSVLLSLCRL 768
AY V F + L + Y+ + L G + +C A +TL++ L RL
Sbjct: 1002 FQAYDFPAVTTAQYSFWLYELCDVYLECLKPVLNGVDQVAAEC--ARQTLYTCLDVGLRL 1059
Query: 769 MAPYTPFLTELMYQNL 784
++P+ PF+TE ++Q L
Sbjct: 1060 LSPFMPFVTEELFQRL 1075
>gi|55741845 valyl-tRNA synthetase 2, mitochondrial [Homo sapiens]
Length = 1063
Score = 122 bits (307), Expect = 2e-27
Identities = 145/600 (24%), Positives = 232/600 (38%), Gaps = 102/600 (17%)
Query: 47 PPFATGLPHYGHILAGTIKDIVTRYAHQSGFHVDRRFGWDCHGLPVEYEIDKTLGIRGPE 106
PP TG H GH L I+D + R+ G V G D G+ + ++K L
Sbjct: 145 PPNVTGSLHIGHALTVAIQDALVRWHRMRGDQVLWVPGSDHAGIATQAVVEKQLW----- 199
Query: 107 DVAKMGITEYNNQCRAIVMRYSAEWKST--------VSRLGRWIDFDNDYKTLYPQFMES 158
+ G+ + R +R +WK + LG +D+D + T+ +
Sbjct: 200 --KERGVRRHELS-REAFLREVWQWKEAKGGEICEQLRALGASLDWDRECFTMDVGSSVA 256
Query: 159 VWWVFKQLYDKGLVYRGVKVMPFSTACNTPLSNFE---------SHQNYKDVQDPSVF-- 207
V F +LY GL+YR +++ +S A + +S+ E + P F
Sbjct: 257 VTEAFVRLYKAGLLYRNHQLVNWSCALRSAISDIEVENRPLPGHTQLRLPGCPTPVSFGL 316
Query: 208 ---VTFPLEEDETVSLVAWTTTPWTLPSNLAVCVNPEMQYVKIKDVARGRLLILMEARLS 264
V FP++ + +V TT P TLP ++AV V+P+
Sbjct: 317 LFSVAFPVDGEPDAEVVVGTTRPETLPGDVAVAVHPD----------------------- 353
Query: 265 ALYKLESDYEILERFPGAYLKGKKYR-PLFDYFLKCKENGAFTVLVDNYVKEEEGTGVVH 323
+S Y +L G++ R PL L ++ D V+ GTG V
Sbjct: 354 -----DSRY--------THLHGRQLRHPLMGQPLP--------LITDYAVQPHVGTGAVK 392
Query: 324 QAPYFGAEDYRVCMDFNIIRKDSLPVCPVDASGCFTTEVTDFA-GQYVKDADKSIIRTLK 382
P D + R P+ + G T+ D+ G + A + I+ L
Sbjct: 393 VTPAHSPADAEMGA-----RHGLSPLNVIAEDGTMTSLCGDWLQGLHRFVAREKIMSVLS 447
Query: 383 EQGRLLVATTFTHSYPFCWRSDTPLIYKAVPSWFVRVENMVDQLLRNNDL-CYWVPELVR 441
E G P C RS + Y WFVR + M + + + +
Sbjct: 448 EWGLFRGLQNHPMVLPICSRSGDVIEYLLKNQWFVRCQEMGARAAKAVESGALELSPSFH 507
Query: 442 EKRFGNWLKDARDWTISRNRYWGTPIPLWV-----SDDFEEVVCIG-SVAELEELSGAKI 495
+K + +W DW +SR +WG IP ++ + E+ +G S AE E++
Sbjct: 508 QKNWQHWFSHIGDWCVSRQLWWGHQIPAYLVVEDHAQGEEDCWVVGRSEAEAREVA---- 563
Query: 496 SDLHRESVDHLTIPSRCGKGSLHRISEVFDCWFESGSMPYAQVHYPFENKREFEDAFPAD 555
++L LT L R +V D WF S P++ + +P E + +P
Sbjct: 564 AELTGRPGAELT---------LERDPDVLDTWFSSALFPFSALGWPQETP-DLARFYPLS 613
Query: 556 FIAEGIDQTRGWFYTLLVLATALFGQPPFKNVIVNGLVLASDGQKMSKRKKNYPDPVSII 615
+ G D W +++L T L GQ PF V+++ +V G+KMSK N DP II
Sbjct: 614 LLETGSDLLLFWVGRMVMLGTQLTGQLPFSKVLLHPMVRDRQGRKMSKSLGNVLDPRDII 673
>gi|7661872 leucyl-tRNA synthetase 2, mitochondrial precursor [Homo
sapiens]
Length = 903
Score = 65.1 bits (157), Expect = 4e-10
Identities = 47/185 (25%), Positives = 76/185 (41%), Gaps = 22/185 (11%)
Query: 11 FPAEEEKILEFWTEFNCFQECLKQS---KHKPKFTFYDGPPFATGLPHYGHILAGTIKDI 67
+ + K +E W ++ K S K KPKF P+ +G H GH+ TI D
Sbjct: 51 YTLQTRKDVEKWWHQRIKEQASKISEADKSKPKFYVLSMFPYPSGKLHMGHVRVYTISDT 110
Query: 68 VTRYAHQSGFHVDRRFGWDCHGLPVE-YEIDKTLGIRGPEDVAKMGITEYNNQCRAIVMR 126
+ R+ G V GWD GLP E +++ L P+ + I Q
Sbjct: 111 IARFQKMRGMQVINPMGWDAFGLPAENAAVERNL---HPQSWTQSNIKHMRKQ------- 160
Query: 127 YSAEWKSTVSRLGRWIDFDNDYKTLYPQFMESVWWVFKQLYDKGLVYRGVKVMPFSTACN 186
+ RLG +D + T P + + ++F +LY+ GL Y+ ++ +
Sbjct: 161 --------LDRLGLCFSWDREITTCLPDYYKWTQYLFIKLYEAGLAYQKEALVNWDPVDQ 212
Query: 187 TPLSN 191
T L+N
Sbjct: 213 TVLAN 217
Score = 47.8 bits (112), Expect = 7e-05
Identities = 55/229 (24%), Positives = 83/229 (36%), Gaps = 59/229 (25%)
Query: 453 RDWTISRNRYWGTPIPLWVSDDFEEVVCIGSVAELEEL--SGAKISDLHRESVDHLTIPS 510
+DW ISR RYWGTPIP+ VC + LE+L + I+ + L + S
Sbjct: 445 KDWLISRQRYWGTPIPI-----VHCPVCGPTPVPLEDLPVTLPNIASFTGKGGPPLAMAS 499
Query: 511 --------RCGKGSLHRISEVFDCWFESG--SMPYAQVHYPFE--NKREFEDAFPADFIA 558
RC KG+ R ++ D + +S Y H P N + P D
Sbjct: 500 EWVNCSCPRC-KGAAKRETDTMDTFVDSAWYYFRYTDPHNPHSPFNTAVADYWMPVDLYI 558
Query: 559 EGIDQTRGWFYTLLVLATALFGQ------PPFKNVIVNGLV------------------- 593
G + + + Q PF ++ GL+
Sbjct: 559 GGKEHAVMHLFYARFFSHFCHDQKMVKHREPFHKLLAQGLIKGQTFRLPSGQYLQREEVD 618
Query: 594 --------------LASDGQKMSKRKKNYPDPVSIIQKYGADALRLYLI 628
L +KMSK K N DP ++++YG D +RLY++
Sbjct: 619 LTGSVPVHAKTKEKLEVTWEKMSKSKHNGVDPEEVVEQYGIDTIRLYIL 667
>gi|108773810 leucyl-tRNA synthetase [Homo sapiens]
Length = 1176
Score = 40.0 bits (92), Expect = 0.014
Identities = 120/582 (20%), Positives = 206/582 (35%), Gaps = 113/582 (19%)
Query: 135 VSRLGRWIDFDNDYKT--LYPQFMESVWWVFKQLYDKGLVYRGVKVMPFSTACNTPLSNF 192
+ R+G +D+ + T + P + V W F L ++ + G + +S P +
Sbjct: 192 LKRMGLKVDWRRSFITTDVNPYYDSFVRWQFLTLRERNKIKFGKRYTIYSPKDGQPCMDH 251
Query: 193 ESH-------QNYKDVQDPSVFVTFPLE----EDETVSLVAWTTTPWTLPSNLAVCVNPE 241
+ Q Y ++ V +P + + + + LVA T P T+ V P+
Sbjct: 252 DRQTGEGVGPQEYTLLK-LKVLEPYPSKLSGLKGKNIFLVAATLRPETMFGQTNCWVRPD 310
Query: 242 MQYVKIKDVARGRLLILMEARLSALY----KLESDYEILERFPGAYLKGKKYR-PLFDYF 296
M+Y+ + V + +A + Y K +++ G + G PL Y
Sbjct: 311 MKYIGFETVNGDIFICTQKAARNMSYQGFTKDNGVVPVVKELMGEEILGASLSAPLTSYK 370
Query: 297 LKCKENGAFTVLVDNYVKEEEGTGVVHQAPYFGAEDYRVCMDFN---------------I 341
+ VL +KE++GTGVV P +D D +
Sbjct: 371 V-------IYVLPMLTIKEDKGTGVVTSVPSDSPDDIAALRDLKKKQALRAKYGIRDDMV 423
Query: 342 IRKDSLPVCPVDASGCFTTE-----------------------------------VTDFA 366
+ + +PV + G + V F
Sbjct: 424 LPFEPVPVIEIPGFGNLSAVTICDELKIQSQNDREKLAEAKEKIYLKGFYEGIMLVDGFK 483
Query: 367 GQYVKDADKSIIRTLKEQGRLLVATTFTHSYPFCWRSDTPLIYKAVPSWFVRV-----EN 421
GQ V+D K+I + + + G L+ RS + W++ +
Sbjct: 484 GQKVQDVKKTIQKKMIDAGDALIY--MEPEKQVMSRSSDECVVALCDQWYLDYGEENWKK 541
Query: 422 MVDQLLRNNDLCYWVPELVREKRFGNWLKDARDWTISRNRYWGTPIPL---WVSDDFEE- 477
Q L+N + E G WL++ SR GT +P W+ + +
Sbjct: 542 QTSQCLKNLETFCEETRRNFEATLG-WLQEH---ACSRTYGLGTHLPWDEQWLIESLSDS 597
Query: 478 --VVCIGSVAELEELSGAKISDLHRESVDHLTI-PSRCGKGSLHRISEVFD-CWFESGSM 533
+ +VA L L G +LH ++ L I P + K EV+D +F+
Sbjct: 598 TIYMAFYTVAHL--LQGG---NLHGQAESPLGIRPQQMTK-------EVWDYVFFKEAPF 645
Query: 534 PYAQVHYPF--ENKREFEDAFPADFIAEGIDQTRGWFYTLLVLATALFGQPPFK---NVI 588
P Q+ + K+EFE +P D G D L A++ + K V
Sbjct: 646 PKTQIAKEKLDQLKQEFEFWYPVDLRVSGKDLVPNHLSYYLYNHVAMWPEQSDKWPTAVR 705
Query: 589 VNGLVLASDGQKMSKRKKNYPDPVSIIQKYGADALRLYLINS 630
NG +L + +KMSK N+ I K+ AD +RL L ++
Sbjct: 706 ANGHLLLNS-EKMSKSTGNFLTLTQAIDKFSADGMRLALADA 746
>gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]
Length = 1946
Score = 37.0 bits (84), Expect = 0.12
Identities = 35/174 (20%), Positives = 81/174 (46%), Gaps = 8/174 (4%)
Query: 864 KSLEK--YIIEELNVRKVTLSTDKNKYGIRLRAEPDHMV-LGKRLKGAFKA---VMTSIK 917
K+LEK + EEL ++V+L+ +KN ++L+AE + + + ++ + K+ + +K
Sbjct: 873 KALEKSEFQREELKAKQVSLTQEKNDLILQLQAEQETLANVEEQCEWLIKSKIQLEARVK 932
Query: 918 QLSSEELEQFQKTGTIVVEGHELHDEDIRLMYTFDQATGGTAQFEAHSDAQALVLLDVTP 977
+LS E+ + + G +L DE L D + E + ++T
Sbjct: 933 ELSERVEEEEEINSELTARGRKLEDECFELKKEIDDLETMLVKSEKEKRTTEHKVKNLTE 992
Query: 978 DQSMVDEGMAREVINRIQKLRKKCNLVPTDEITVYYKAKSEGTYLNSVIESHTE 1031
+ ++E +++ +NR K+ ++ + D++ + + S + N +E +
Sbjct: 993 EVEFLNEDISK--LNRAAKVVQEAHQQTLDDLHMEEEKLSSLSKANLKLEQQVD 1044
>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
sapiens]
Length = 1940
Score = 36.2 bits (82), Expect = 0.20
Identities = 37/200 (18%), Positives = 90/200 (45%), Gaps = 8/200 (4%)
Query: 848 KEIVVIHQDPEALKDIKSLEKYIIEELNVRKVTLSTDKNKYGIRLRAEPDHMV-----LG 902
KE+ + ++ + KD + + +EL + VTL +KN ++++AE ++++
Sbjct: 848 KEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAEERCD 907
Query: 903 KRLKGAFKAVMTSIKQLSSEELEQFQKTGTIVVEGHELHDEDIRLMYTFDQATGGTAQFE 962
+ +K F+ + IK+++ ++ + + + +L DE L D A+ E
Sbjct: 908 QLIKAKFQ-LEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVE 966
Query: 963 AHSDAQALVLLDVTPDQSMVDEGMAREVINRIQKLRKKCNLVPTDEITVYYKAKSEGTYL 1022
A + ++T + S +DE +A+ + R +K ++ + D++ +
Sbjct: 967 KEKHATENKVKNLTEELSGLDETIAK--LTREKKALQEAHQQALDDLQAEEDKVNSLNKT 1024
Query: 1023 NSVIESHTEFIFTTIKAPLK 1042
S +E E + ++++ K
Sbjct: 1025 KSKLEQQVEDLESSLEQEKK 1044
>gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta [Homo
sapiens]
Length = 1983
Score = 35.4 bits (80), Expect = 0.35
Identities = 29/145 (20%), Positives = 64/145 (44%), Gaps = 4/145 (2%)
Query: 848 KEIVVIHQDPEALKDIKSLEKYIIEELNVRKVTLSTDKNKYGIRLRAEPDHMV-LGKRLK 906
+E+ + + L+ + + +EL V+++ +KN ++L+AE D++ +R
Sbjct: 896 EELAALRAELRGLRGALAAAEAKRQELEETHVSITQEKNDLALQLQAEQDNLADAEERCH 955
Query: 907 GAFKAVMT---SIKQLSSEELEQFQKTGTIVVEGHELHDEDIRLMYTFDQATGGTAQFEA 963
K+ + +K+LS ++ + + +L DE L D A+ E
Sbjct: 956 LLIKSKVQLEGKVKELSERLEDEEEVNADLAARRRKLEDECTELKKDIDDLKLTLAKAEK 1015
Query: 964 HSDAQALVLLDVTPDQSMVDEGMAR 988
A + ++T + + +DE +AR
Sbjct: 1016 EKQATENKVKNLTEEMAALDESVAR 1040
>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
sapiens]
Length = 1938
Score = 35.0 bits (79), Expect = 0.45
Identities = 32/188 (17%), Positives = 88/188 (46%), Gaps = 6/188 (3%)
Query: 848 KEIVVIHQDPEALKDIKSLEKYIIEELNVRKVTLSTDKNKYGIRLRAEPDHMV-LGKRLK 906
KE+ + +D E K+ + + +EL + V+L +KN +++++E ++++ +R +
Sbjct: 851 KEMATMKEDFERTKEELARSEARRKELEEKMVSLLQEKNDLQLQVQSETENLMDAEERCE 910
Query: 907 GAFKA---VMTSIKQLSSEELEQFQKTGTIVVEGHELHDEDIRLMYTFDQATGGTAQFEA 963
G K+ + +K+L+ E+ + +V + L D+ L D + E
Sbjct: 911 GLIKSKILLEAKVKELTERLEEEEEMNSELVAKKRNLEDKCSSLKRDIDDLELTLTKVEK 970
Query: 964 HSDAQALVLLDVTPDQSMVDEGMAREVINRIQKLRKKCNLVPTDEITVYYKAKSEGTYLN 1023
A + +++ + + ++E +++ + + +K ++ + D++ V + +N
Sbjct: 971 EKHATENKVKNLSEEMTALEENISK--LTKEKKSLQEAHQQTLDDLQVEEDKVNGLIKIN 1028
Query: 1024 SVIESHTE 1031
+ +E T+
Sbjct: 1029 AKLEQQTD 1036
>gi|38569430 activating transcription factor 7 interacting protein 2
[Homo sapiens]
Length = 682
Score = 34.7 bits (78), Expect = 0.59
Identities = 33/129 (25%), Positives = 51/129 (39%), Gaps = 12/129 (9%)
Query: 1115 KSVVTSIFGVKNTELAVFHDETEIQNQTDLLSLSGKTLC------VTAGSAPSLINSSST 1168
+S VTS G K T+ VFH ET +++ S LC V P+L+NS ++
Sbjct: 182 ESTVTSTVGDKKTDQMVFHLETNSNSESHDKRQSDNILCSEDSGFVPVEKTPNLVNSVTS 241
Query: 1169 LLCQYINLQLLNAKPQECLMGTVGTLLLENPLGQNGL-THQGLLYEAAKVFGLRSRKLKL 1227
C L K EC ++ + Q+ L T+ Y+ ++F +K
Sbjct: 242 NNCADDIL-----KTDECSRTSISNCESADSTWQSSLDTNNNSHYQKKRMFSENEENVKR 296
Query: 1228 FLNETQTQE 1236
Q E
Sbjct: 297 MKTSEQINE 305
>gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens]
Length = 1684
Score = 34.3 bits (77), Expect = 0.77
Identities = 35/142 (24%), Positives = 65/142 (45%), Gaps = 19/142 (13%)
Query: 812 ELIDKKTESAVSQMQSVIELGRVIRD------RKTIPIKYPLKEIVVIHQDPEALKD-IK 864
EL+ K + + + R++++ K I+ +EI + Q E L++ I
Sbjct: 1146 ELVKKDAQQTTLMNMEIADYERLMKELNQKLTNKNNKIEDLEQEIKIQKQKQETLQEEIT 1205
Query: 865 SLEKYI--IEELNVR-KVTLSTDKNKYGIRLRAEPDHMVLGKRLKGAFKAVMTSIKQLSS 921
SL+ + EE N + K L K + +AE DH++L LKG +A S
Sbjct: 1206 SLQSSVQQYEEKNTKIKQLLVKTKKELADSKQAETDHLILQASLKGELEA--------SQ 1257
Query: 922 EELEQFQ-KTGTIVVEGHELHD 942
+++E ++ + I E H++H+
Sbjct: 1258 QQVEVYKIQLAEITSEKHKIHE 1279
>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal
[Homo sapiens]
Length = 1937
Score = 34.3 bits (77), Expect = 0.77
Identities = 30/145 (20%), Positives = 66/145 (45%), Gaps = 4/145 (2%)
Query: 848 KEIVVIHQDPEALKDIKSLEKYIIEELNVRKVTLSTDKNKYGIRLRAEPDHMV-LGKRLK 906
KE+ + ++ + KD + + +EL + VTL +KN +++++E D + +R +
Sbjct: 850 KEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLADAEERCE 909
Query: 907 GAFK---AVMTSIKQLSSEELEQFQKTGTIVVEGHELHDEDIRLMYTFDQATGGTAQFEA 963
K + IK+++ E+ + + + +L DE L D A+ E
Sbjct: 910 QLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEK 969
Query: 964 HSDAQALVLLDVTPDQSMVDEGMAR 988
A + ++T + + +DE +A+
Sbjct: 970 EKHATENKVKNLTEEMAGLDETIAK 994
>gi|28269672 serologically defined colon cancer antigen 8 [Homo
sapiens]
Length = 713
Score = 34.3 bits (77), Expect = 0.77
Identities = 34/143 (23%), Positives = 61/143 (42%), Gaps = 14/143 (9%)
Query: 855 QDPEALKDIKSLEKYIIEELNVRKVTLSTDKNKYGIRLRAEPDHMVLGKRLKGAFKAVMT 914
Q EA D E+Y+ L T +N + +L+ E L K+L+ + +
Sbjct: 572 QQMEAQHDKTENEQYL----------LLTSQNTFLTKLKEEC--CTLAKKLEQISQKTRS 619
Query: 915 SIKQLSSEELEQFQKTGTIVVEGHELHDEDIRLMYTFDQATGGTAQFEAHSD--AQALVL 972
I QLS E+ + K G + EL ++ ++ + Q + HS AQ LV
Sbjct: 620 EIAQLSQEKRYTYDKLGKLQRRNEELEEQCVQHGRVHETMKQRLRQLDKHSQATAQQLVQ 679
Query: 973 LDVTPDQSMVDEGMAREVINRIQ 995
L +Q +++ E ++R++
Sbjct: 680 LLSKQNQLLLERQSLSEEVDRLR 702
>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 33.1 bits (74), Expect = 1.7
Identities = 29/145 (20%), Positives = 66/145 (45%), Gaps = 4/145 (2%)
Query: 848 KEIVVIHQDPEALKDIKSLEKYIIEELNVRKVTLSTDKNKYGIRLRAEPDHMV-LGKRLK 906
KE+ + ++ + +KD + + +EL + VTL +KN ++++AE + + +R
Sbjct: 853 KEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCD 912
Query: 907 GAFKA---VMTSIKQLSSEELEQFQKTGTIVVEGHELHDEDIRLMYTFDQATGGTAQFEA 963
K + IK+++ ++ + + + +L DE L D A+ E
Sbjct: 913 QLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEK 972
Query: 964 HSDAQALVLLDVTPDQSMVDEGMAR 988
A + ++T + + +DE +A+
Sbjct: 973 EKHATENKVKNLTEEMAGLDETIAK 997
>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 33.1 bits (74), Expect = 1.7
Identities = 29/145 (20%), Positives = 66/145 (45%), Gaps = 4/145 (2%)
Query: 848 KEIVVIHQDPEALKDIKSLEKYIIEELNVRKVTLSTDKNKYGIRLRAEPDHMV-LGKRLK 906
KE+ + ++ + +KD + + +EL + VTL +KN ++++AE + + +R
Sbjct: 853 KEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCD 912
Query: 907 GAFKA---VMTSIKQLSSEELEQFQKTGTIVVEGHELHDEDIRLMYTFDQATGGTAQFEA 963
K + IK+++ ++ + + + +L DE L D A+ E
Sbjct: 913 QLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEK 972
Query: 964 HSDAQALVLLDVTPDQSMVDEGMAR 988
A + ++T + + +DE +A+
Sbjct: 973 EKHATENKVKNLTEEMAGLDETIAK 997
>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
sapiens]
Length = 1939
Score = 32.3 bits (72), Expect = 2.9
Identities = 30/145 (20%), Positives = 65/145 (44%), Gaps = 4/145 (2%)
Query: 848 KEIVVIHQDPEALKDIKSLEKYIIEELNVRKVTLSTDKNKYGIRLRAEPDHMV-LGKRLK 906
KE+ + ++ E K+ + + +EL + VTL +KN ++++AE D + +R
Sbjct: 851 KEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADSLADAEERCD 910
Query: 907 GAFKA---VMTSIKQLSSEELEQFQKTGTIVVEGHELHDEDIRLMYTFDQATGGTAQFEA 963
K + IK+++ ++ + + + +L DE L D A+ E
Sbjct: 911 QLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEK 970
Query: 964 HSDAQALVLLDVTPDQSMVDEGMAR 988
A + ++T + + +DE +A+
Sbjct: 971 EKHATENKVKNLTEEMAGLDETIAK 995
>gi|139394579 zinc finger and BTB domain containing 40 [Homo sapiens]
Length = 1239
Score = 32.3 bits (72), Expect = 2.9
Identities = 13/27 (48%), Positives = 22/27 (81%)
Query: 1043 PYPVSPSDKVLIQEKTQLKGSELEITL 1069
P PV+P+++V+ E+TQL GS++ +TL
Sbjct: 1180 PEPVAPTEQVITLEETQLAGSQVFVTL 1206
>gi|139394556 zinc finger and BTB domain containing 40 [Homo sapiens]
Length = 1239
Score = 32.3 bits (72), Expect = 2.9
Identities = 13/27 (48%), Positives = 22/27 (81%)
Query: 1043 PYPVSPSDKVLIQEKTQLKGSELEITL 1069
P PV+P+++V+ E+TQL GS++ +TL
Sbjct: 1180 PEPVAPTEQVITLEETQLAGSQVFVTL 1206
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 32.0 bits (71), Expect = 3.8
Identities = 38/165 (23%), Positives = 77/165 (46%), Gaps = 15/165 (9%)
Query: 793 VQDKDTLSIHYLMLP-------RVREELIDKKTESAVSQMQSVIELGRVIRDRKTIPIKY 845
+Q+K+ L+ H +P R RE+LI+KK + A + + + + + +++ + K
Sbjct: 1778 IQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQKRERWINSMEELTKNKMILYQKK 1837
Query: 846 PL-KEIVVIHQDPEALKDIKSLEKYIIEELNVRKVTLSTDKNKYGI--RLRAEPDHMVLG 902
L +E + Q+ E L K Y E L K L KNK G+ ++ A+ +
Sbjct: 1838 NLAQEKKNLAQEKEKLAQRKENLLYNKERLTHSKKQLVQVKNKLGMFNKILAQVE----- 1892
Query: 903 KRLKGAFKAVMTSIKQLSSEELEQFQKTGTIVVEGHELHDEDIRL 947
++L + V+ ++L+ E + Q ++ + +L E ++L
Sbjct: 1893 EKLTQEKETVIKKKEKLAETEKKLVQVEDSLAKKQEKLAQEKMKL 1937
>gi|156104874 envoplakin [Homo sapiens]
Length = 2033
Score = 32.0 bits (71), Expect = 3.8
Identities = 25/86 (29%), Positives = 46/86 (53%), Gaps = 9/86 (10%)
Query: 816 KKTESAVSQMQSVIE-LGRVIRDRKTIPIKYPLKEIVVIHQDPEALKDIKSLEKYIIEEL 874
K+ E AV+++Q+ IE L R I ++ K +KE+ + QDP L++ L + ++EE
Sbjct: 1107 KQAEEAVAKLQARIEDLERAI---SSVEPKVIVKEVKKVEQDPGLLQESSRL-RSLLEEE 1162
Query: 875 NVRKVTLSTD----KNKYGIRLRAEP 896
+ TL+ + +KY + + P
Sbjct: 1163 RTKNATLARELSDLHSKYSVVEKQRP 1188
>gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo
sapiens]
Length = 1939
Score = 32.0 bits (71), Expect = 3.8
Identities = 30/145 (20%), Positives = 65/145 (44%), Gaps = 4/145 (2%)
Query: 848 KEIVVIHQDPEALKDIKSLEKYIIEELNVRKVTLSTDKNKYGIRLRAEPDHMV-LGKRLK 906
KE+ + ++ E K+ + + +EL + VTL +KN ++++AE D + +R
Sbjct: 851 KEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADALADAEERCD 910
Query: 907 GAFKA---VMTSIKQLSSEELEQFQKTGTIVVEGHELHDEDIRLMYTFDQATGGTAQFEA 963
K + IK+++ ++ + + + +L DE L D A+ E
Sbjct: 911 QLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEK 970
Query: 964 HSDAQALVLLDVTPDQSMVDEGMAR 988
A + ++T + + +DE +A+
Sbjct: 971 EKHATENKVKNLTEEMAGLDETIAK 995
>gi|148806872 lupus brain antigen 1 [Homo sapiens]
Length = 2375
Score = 32.0 bits (71), Expect = 3.8
Identities = 19/55 (34%), Positives = 28/55 (50%), Gaps = 6/55 (10%)
Query: 650 KDVLLPWYNAYRFLIQNVLRLQKEEEIEFLYNENTVRESPNITDRWILSFMQSLI 704
K++L P Y ++RF R +E I FL+ + R TD W LS MQ+ +
Sbjct: 1696 KEILKPNYKSFRFY-----RFALKEYIHFLFENESARNRRESTDLW-LSAMQAFL 1744
>gi|114326455 chromodomain helicase DNA binding protein 8 [Homo
sapiens]
Length = 2302
Score = 31.6 bits (70), Expect = 5.0
Identities = 24/87 (27%), Positives = 44/87 (50%), Gaps = 15/87 (17%)
Query: 902 GKRLKGAFK--AVMTSIKQLSSE--ELEQFQKTGTIVVEGHELHDEDIRLMYTFDQATGG 957
G+ + GA+K A++T+ + + S+ EL + + I+ E H L + + +L+ +
Sbjct: 632 GRLIPGAYKFDALITTFEMILSDCPELREIEWRCVIIDEAHRLKNRNCKLLDSLK----- 686
Query: 958 TAQFEAHSDAQALVLLDVTPDQSMVDE 984
H D + VLL TP Q+ V+E
Sbjct: 687 ------HMDLEHKVLLTGTPLQNTVEE 707
>gi|21359963 ring finger and WD repeat domain 2 isoform a [Homo
sapiens]
Length = 731
Score = 31.2 bits (69), Expect = 6.5
Identities = 23/86 (26%), Positives = 45/86 (52%), Gaps = 6/86 (6%)
Query: 795 DKDTLSIHYLMLPRVREELIDKK----TESAVSQMQSVIELGRVIRDRKTIPIKYPLKEI 850
D+D L + + L + E L+ KK ES +Q+Q ++E +V R K ++ KE+
Sbjct: 229 DQDNLDLANVNL--MLELLVQKKKQLEAESHAAQLQILMEFLKVARRNKREQLEQIQKEL 286
Query: 851 VVIHQDPEALKDIKSLEKYIIEELNV 876
V+ +D + ++++ L + E+ V
Sbjct: 287 SVLEEDIKRVEEMSGLYSPVSEDSTV 312
>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
sapiens]
Length = 1935
Score = 30.8 bits (68), Expect = 8.5
Identities = 28/145 (19%), Positives = 65/145 (44%), Gaps = 4/145 (2%)
Query: 848 KEIVVIHQDPEALKDIKSLEKYIIEELNVRKVTLSTDKNKYGIRLRAEPDHMV-LGKRLK 906
KE+ + ++ LK+ + +EL + V+L +KN ++++AE D++ +R
Sbjct: 847 KEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCD 906
Query: 907 GAFK---AVMTSIKQLSSEELEQFQKTGTIVVEGHELHDEDIRLMYTFDQATGGTAQFEA 963
K + +K+++ ++ + + + +L DE L D A+ E
Sbjct: 907 QLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEK 966
Query: 964 HSDAQALVLLDVTPDQSMVDEGMAR 988
A + ++T + + +DE +A+
Sbjct: 967 EKHATENKVKNLTEEMAGLDEIIAK 991
>gi|14043022 methionyl-tRNA synthetase [Homo sapiens]
Length = 900
Score = 30.8 bits (68), Expect = 8.5
Identities = 22/73 (30%), Positives = 37/73 (50%), Gaps = 9/73 (12%)
Query: 408 IYKAVPSWFVRVENMVDQLLRNNDLCYWVPELVREKRFGNWLKDA-RDWTISRNRYWGTP 466
++ +P R+E + + L +D W P R +WL+D + I+R+ WGTP
Sbjct: 450 LFLDLPKLEKRLEEWLGRTLPGSD---WTPNAQFITR--SWLRDGLKPRCITRDLKWGTP 504
Query: 467 IPLWVSDDFEEVV 479
+PL + FE+ V
Sbjct: 505 VPL---EGFEDKV 514
>gi|24308436 methionine-tRNA synthetase 2 precursor [Homo sapiens]
Length = 593
Score = 30.8 bits (68), Expect = 8.5
Identities = 14/35 (40%), Positives = 19/35 (54%)
Query: 598 GQKMSKRKKNYPDPVSIIQKYGADALRLYLINSPV 632
GQKMSK N DP + + +Y D R +L+ V
Sbjct: 345 GQKMSKSLGNVVDPRTCLNRYTVDGFRYFLLRQGV 379
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.137 0.411
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 47,171,141
Number of Sequences: 37866
Number of extensions: 2139247
Number of successful extensions: 4331
Number of sequences better than 10.0: 29
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 19
Number of HSP's that attempted gapping in prelim test: 4269
Number of HSP's gapped (non-prelim): 55
length of query: 1262
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1148
effective length of database: 13,930,794
effective search space: 15992551512
effective search space used: 15992551512
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.