BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|94721239 isoleucine tRNA synthetase [Homo sapiens] (1262 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|94721239 isoleucine tRNA synthetase [Homo sapiens] 2554 0.0 gi|94721241 isoleucine tRNA synthetase [Homo sapiens] 2554 0.0 gi|46852147 mitochondrial isoleucine tRNA synthetase [Homo sapiens] 282 1e-75 gi|5454158 valyl-tRNA synthetase [Homo sapiens] 149 2e-35 gi|55741845 valyl-tRNA synthetase 2, mitochondrial [Homo sapiens] 122 2e-27 gi|7661872 leucyl-tRNA synthetase 2, mitochondrial precursor [Ho... 65 4e-10 gi|108773810 leucyl-tRNA synthetase [Homo sapiens] 40 0.014 gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens] 37 0.12 gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H... 36 0.20 gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta ... 35 0.35 gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 35 0.45 gi|38569430 activating transcription factor 7 interacting protei... 35 0.59 gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens] 34 0.77 gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [... 34 0.77 gi|28269672 serologically defined colon cancer antigen 8 [Homo s... 34 0.77 gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo... 33 1.7 gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo... 33 1.7 gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo... 32 2.9 gi|139394579 zinc finger and BTB domain containing 40 [Homo sapi... 32 2.9 gi|139394556 zinc finger and BTB domain containing 40 [Homo sapi... 32 2.9 gi|221219020 NYD-SP11 protein [Homo sapiens] 32 3.8 gi|156104874 envoplakin [Homo sapiens] 32 3.8 gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo ... 32 3.8 gi|148806872 lupus brain antigen 1 [Homo sapiens] 32 3.8 gi|114326455 chromodomain helicase DNA binding protein 8 [Homo s... 32 5.0 gi|21359963 ring finger and WD repeat domain 2 isoform a [Homo s... 31 6.5 gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s... 31 8.5 gi|14043022 methionyl-tRNA synthetase [Homo sapiens] 31 8.5 gi|24308436 methionine-tRNA synthetase 2 precursor [Homo sapiens] 31 8.5 >gi|94721239 isoleucine tRNA synthetase [Homo sapiens] Length = 1262 Score = 2554 bits (6619), Expect = 0.0 Identities = 1262/1262 (100%), Positives = 1262/1262 (100%) Query: 1 MLQQVPENINFPAEEEKILEFWTEFNCFQECLKQSKHKPKFTFYDGPPFATGLPHYGHIL 60 MLQQVPENINFPAEEEKILEFWTEFNCFQECLKQSKHKPKFTFYDGPPFATGLPHYGHIL Sbjct: 1 MLQQVPENINFPAEEEKILEFWTEFNCFQECLKQSKHKPKFTFYDGPPFATGLPHYGHIL 60 Query: 61 AGTIKDIVTRYAHQSGFHVDRRFGWDCHGLPVEYEIDKTLGIRGPEDVAKMGITEYNNQC 120 AGTIKDIVTRYAHQSGFHVDRRFGWDCHGLPVEYEIDKTLGIRGPEDVAKMGITEYNNQC Sbjct: 61 AGTIKDIVTRYAHQSGFHVDRRFGWDCHGLPVEYEIDKTLGIRGPEDVAKMGITEYNNQC 120 Query: 121 RAIVMRYSAEWKSTVSRLGRWIDFDNDYKTLYPQFMESVWWVFKQLYDKGLVYRGVKVMP 180 RAIVMRYSAEWKSTVSRLGRWIDFDNDYKTLYPQFMESVWWVFKQLYDKGLVYRGVKVMP Sbjct: 121 RAIVMRYSAEWKSTVSRLGRWIDFDNDYKTLYPQFMESVWWVFKQLYDKGLVYRGVKVMP 180 Query: 181 FSTACNTPLSNFESHQNYKDVQDPSVFVTFPLEEDETVSLVAWTTTPWTLPSNLAVCVNP 240 FSTACNTPLSNFESHQNYKDVQDPSVFVTFPLEEDETVSLVAWTTTPWTLPSNLAVCVNP Sbjct: 181 FSTACNTPLSNFESHQNYKDVQDPSVFVTFPLEEDETVSLVAWTTTPWTLPSNLAVCVNP 240 Query: 241 EMQYVKIKDVARGRLLILMEARLSALYKLESDYEILERFPGAYLKGKKYRPLFDYFLKCK 300 EMQYVKIKDVARGRLLILMEARLSALYKLESDYEILERFPGAYLKGKKYRPLFDYFLKCK Sbjct: 241 EMQYVKIKDVARGRLLILMEARLSALYKLESDYEILERFPGAYLKGKKYRPLFDYFLKCK 300 Query: 301 ENGAFTVLVDNYVKEEEGTGVVHQAPYFGAEDYRVCMDFNIIRKDSLPVCPVDASGCFTT 360 ENGAFTVLVDNYVKEEEGTGVVHQAPYFGAEDYRVCMDFNIIRKDSLPVCPVDASGCFTT Sbjct: 301 ENGAFTVLVDNYVKEEEGTGVVHQAPYFGAEDYRVCMDFNIIRKDSLPVCPVDASGCFTT 360 Query: 361 EVTDFAGQYVKDADKSIIRTLKEQGRLLVATTFTHSYPFCWRSDTPLIYKAVPSWFVRVE 420 EVTDFAGQYVKDADKSIIRTLKEQGRLLVATTFTHSYPFCWRSDTPLIYKAVPSWFVRVE Sbjct: 361 EVTDFAGQYVKDADKSIIRTLKEQGRLLVATTFTHSYPFCWRSDTPLIYKAVPSWFVRVE 420 Query: 421 NMVDQLLRNNDLCYWVPELVREKRFGNWLKDARDWTISRNRYWGTPIPLWVSDDFEEVVC 480 NMVDQLLRNNDLCYWVPELVREKRFGNWLKDARDWTISRNRYWGTPIPLWVSDDFEEVVC Sbjct: 421 NMVDQLLRNNDLCYWVPELVREKRFGNWLKDARDWTISRNRYWGTPIPLWVSDDFEEVVC 480 Query: 481 IGSVAELEELSGAKISDLHRESVDHLTIPSRCGKGSLHRISEVFDCWFESGSMPYAQVHY 540 IGSVAELEELSGAKISDLHRESVDHLTIPSRCGKGSLHRISEVFDCWFESGSMPYAQVHY Sbjct: 481 IGSVAELEELSGAKISDLHRESVDHLTIPSRCGKGSLHRISEVFDCWFESGSMPYAQVHY 540 Query: 541 PFENKREFEDAFPADFIAEGIDQTRGWFYTLLVLATALFGQPPFKNVIVNGLVLASDGQK 600 PFENKREFEDAFPADFIAEGIDQTRGWFYTLLVLATALFGQPPFKNVIVNGLVLASDGQK Sbjct: 541 PFENKREFEDAFPADFIAEGIDQTRGWFYTLLVLATALFGQPPFKNVIVNGLVLASDGQK 600 Query: 601 MSKRKKNYPDPVSIIQKYGADALRLYLINSPVVRAENLRFKEEGVRDVLKDVLLPWYNAY 660 MSKRKKNYPDPVSIIQKYGADALRLYLINSPVVRAENLRFKEEGVRDVLKDVLLPWYNAY Sbjct: 601 MSKRKKNYPDPVSIIQKYGADALRLYLINSPVVRAENLRFKEEGVRDVLKDVLLPWYNAY 660 Query: 661 RFLIQNVLRLQKEEEIEFLYNENTVRESPNITDRWILSFMQSLIGFFETEMAAYRLYTVV 720 RFLIQNVLRLQKEEEIEFLYNENTVRESPNITDRWILSFMQSLIGFFETEMAAYRLYTVV Sbjct: 661 RFLIQNVLRLQKEEEIEFLYNENTVRESPNITDRWILSFMQSLIGFFETEMAAYRLYTVV 720 Query: 721 PRLVKFVDILTNWYVRMNRRRLKGENGMEDCVMALETLFSVLLSLCRLMAPYTPFLTELM 780 PRLVKFVDILTNWYVRMNRRRLKGENGMEDCVMALETLFSVLLSLCRLMAPYTPFLTELM Sbjct: 721 PRLVKFVDILTNWYVRMNRRRLKGENGMEDCVMALETLFSVLLSLCRLMAPYTPFLTELM 780 Query: 781 YQNLKVLIDPVSVQDKDTLSIHYLMLPRVREELIDKKTESAVSQMQSVIELGRVIRDRKT 840 YQNLKVLIDPVSVQDKDTLSIHYLMLPRVREELIDKKTESAVSQMQSVIELGRVIRDRKT Sbjct: 781 YQNLKVLIDPVSVQDKDTLSIHYLMLPRVREELIDKKTESAVSQMQSVIELGRVIRDRKT 840 Query: 841 IPIKYPLKEIVVIHQDPEALKDIKSLEKYIIEELNVRKVTLSTDKNKYGIRLRAEPDHMV 900 IPIKYPLKEIVVIHQDPEALKDIKSLEKYIIEELNVRKVTLSTDKNKYGIRLRAEPDHMV Sbjct: 841 IPIKYPLKEIVVIHQDPEALKDIKSLEKYIIEELNVRKVTLSTDKNKYGIRLRAEPDHMV 900 Query: 901 LGKRLKGAFKAVMTSIKQLSSEELEQFQKTGTIVVEGHELHDEDIRLMYTFDQATGGTAQ 960 LGKRLKGAFKAVMTSIKQLSSEELEQFQKTGTIVVEGHELHDEDIRLMYTFDQATGGTAQ Sbjct: 901 LGKRLKGAFKAVMTSIKQLSSEELEQFQKTGTIVVEGHELHDEDIRLMYTFDQATGGTAQ 960 Query: 961 FEAHSDAQALVLLDVTPDQSMVDEGMAREVINRIQKLRKKCNLVPTDEITVYYKAKSEGT 1020 FEAHSDAQALVLLDVTPDQSMVDEGMAREVINRIQKLRKKCNLVPTDEITVYYKAKSEGT Sbjct: 961 FEAHSDAQALVLLDVTPDQSMVDEGMAREVINRIQKLRKKCNLVPTDEITVYYKAKSEGT 1020 Query: 1021 YLNSVIESHTEFIFTTIKAPLKPYPVSPSDKVLIQEKTQLKGSELEITLTRGSSLPGPAC 1080 YLNSVIESHTEFIFTTIKAPLKPYPVSPSDKVLIQEKTQLKGSELEITLTRGSSLPGPAC Sbjct: 1021 YLNSVIESHTEFIFTTIKAPLKPYPVSPSDKVLIQEKTQLKGSELEITLTRGSSLPGPAC 1080 Query: 1081 AYVNLNICANGSEQGGVLLLENPKGDNRLDLLKLKSVVTSIFGVKNTELAVFHDETEIQN 1140 AYVNLNICANGSEQGGVLLLENPKGDNRLDLLKLKSVVTSIFGVKNTELAVFHDETEIQN Sbjct: 1081 AYVNLNICANGSEQGGVLLLENPKGDNRLDLLKLKSVVTSIFGVKNTELAVFHDETEIQN 1140 Query: 1141 QTDLLSLSGKTLCVTAGSAPSLINSSSTLLCQYINLQLLNAKPQECLMGTVGTLLLENPL 1200 QTDLLSLSGKTLCVTAGSAPSLINSSSTLLCQYINLQLLNAKPQECLMGTVGTLLLENPL Sbjct: 1141 QTDLLSLSGKTLCVTAGSAPSLINSSSTLLCQYINLQLLNAKPQECLMGTVGTLLLENPL 1200 Query: 1201 GQNGLTHQGLLYEAAKVFGLRSRKLKLFLNETQTQEITEDIPVKTLNMKTVYVSVLPTTA 1260 GQNGLTHQGLLYEAAKVFGLRSRKLKLFLNETQTQEITEDIPVKTLNMKTVYVSVLPTTA Sbjct: 1201 GQNGLTHQGLLYEAAKVFGLRSRKLKLFLNETQTQEITEDIPVKTLNMKTVYVSVLPTTA 1260 Query: 1261 DF 1262 DF Sbjct: 1261 DF 1262 >gi|94721241 isoleucine tRNA synthetase [Homo sapiens] Length = 1262 Score = 2554 bits (6619), Expect = 0.0 Identities = 1262/1262 (100%), Positives = 1262/1262 (100%) Query: 1 MLQQVPENINFPAEEEKILEFWTEFNCFQECLKQSKHKPKFTFYDGPPFATGLPHYGHIL 60 MLQQVPENINFPAEEEKILEFWTEFNCFQECLKQSKHKPKFTFYDGPPFATGLPHYGHIL Sbjct: 1 MLQQVPENINFPAEEEKILEFWTEFNCFQECLKQSKHKPKFTFYDGPPFATGLPHYGHIL 60 Query: 61 AGTIKDIVTRYAHQSGFHVDRRFGWDCHGLPVEYEIDKTLGIRGPEDVAKMGITEYNNQC 120 AGTIKDIVTRYAHQSGFHVDRRFGWDCHGLPVEYEIDKTLGIRGPEDVAKMGITEYNNQC Sbjct: 61 AGTIKDIVTRYAHQSGFHVDRRFGWDCHGLPVEYEIDKTLGIRGPEDVAKMGITEYNNQC 120 Query: 121 RAIVMRYSAEWKSTVSRLGRWIDFDNDYKTLYPQFMESVWWVFKQLYDKGLVYRGVKVMP 180 RAIVMRYSAEWKSTVSRLGRWIDFDNDYKTLYPQFMESVWWVFKQLYDKGLVYRGVKVMP Sbjct: 121 RAIVMRYSAEWKSTVSRLGRWIDFDNDYKTLYPQFMESVWWVFKQLYDKGLVYRGVKVMP 180 Query: 181 FSTACNTPLSNFESHQNYKDVQDPSVFVTFPLEEDETVSLVAWTTTPWTLPSNLAVCVNP 240 FSTACNTPLSNFESHQNYKDVQDPSVFVTFPLEEDETVSLVAWTTTPWTLPSNLAVCVNP Sbjct: 181 FSTACNTPLSNFESHQNYKDVQDPSVFVTFPLEEDETVSLVAWTTTPWTLPSNLAVCVNP 240 Query: 241 EMQYVKIKDVARGRLLILMEARLSALYKLESDYEILERFPGAYLKGKKYRPLFDYFLKCK 300 EMQYVKIKDVARGRLLILMEARLSALYKLESDYEILERFPGAYLKGKKYRPLFDYFLKCK Sbjct: 241 EMQYVKIKDVARGRLLILMEARLSALYKLESDYEILERFPGAYLKGKKYRPLFDYFLKCK 300 Query: 301 ENGAFTVLVDNYVKEEEGTGVVHQAPYFGAEDYRVCMDFNIIRKDSLPVCPVDASGCFTT 360 ENGAFTVLVDNYVKEEEGTGVVHQAPYFGAEDYRVCMDFNIIRKDSLPVCPVDASGCFTT Sbjct: 301 ENGAFTVLVDNYVKEEEGTGVVHQAPYFGAEDYRVCMDFNIIRKDSLPVCPVDASGCFTT 360 Query: 361 EVTDFAGQYVKDADKSIIRTLKEQGRLLVATTFTHSYPFCWRSDTPLIYKAVPSWFVRVE 420 EVTDFAGQYVKDADKSIIRTLKEQGRLLVATTFTHSYPFCWRSDTPLIYKAVPSWFVRVE Sbjct: 361 EVTDFAGQYVKDADKSIIRTLKEQGRLLVATTFTHSYPFCWRSDTPLIYKAVPSWFVRVE 420 Query: 421 NMVDQLLRNNDLCYWVPELVREKRFGNWLKDARDWTISRNRYWGTPIPLWVSDDFEEVVC 480 NMVDQLLRNNDLCYWVPELVREKRFGNWLKDARDWTISRNRYWGTPIPLWVSDDFEEVVC Sbjct: 421 NMVDQLLRNNDLCYWVPELVREKRFGNWLKDARDWTISRNRYWGTPIPLWVSDDFEEVVC 480 Query: 481 IGSVAELEELSGAKISDLHRESVDHLTIPSRCGKGSLHRISEVFDCWFESGSMPYAQVHY 540 IGSVAELEELSGAKISDLHRESVDHLTIPSRCGKGSLHRISEVFDCWFESGSMPYAQVHY Sbjct: 481 IGSVAELEELSGAKISDLHRESVDHLTIPSRCGKGSLHRISEVFDCWFESGSMPYAQVHY 540 Query: 541 PFENKREFEDAFPADFIAEGIDQTRGWFYTLLVLATALFGQPPFKNVIVNGLVLASDGQK 600 PFENKREFEDAFPADFIAEGIDQTRGWFYTLLVLATALFGQPPFKNVIVNGLVLASDGQK Sbjct: 541 PFENKREFEDAFPADFIAEGIDQTRGWFYTLLVLATALFGQPPFKNVIVNGLVLASDGQK 600 Query: 601 MSKRKKNYPDPVSIIQKYGADALRLYLINSPVVRAENLRFKEEGVRDVLKDVLLPWYNAY 660 MSKRKKNYPDPVSIIQKYGADALRLYLINSPVVRAENLRFKEEGVRDVLKDVLLPWYNAY Sbjct: 601 MSKRKKNYPDPVSIIQKYGADALRLYLINSPVVRAENLRFKEEGVRDVLKDVLLPWYNAY 660 Query: 661 RFLIQNVLRLQKEEEIEFLYNENTVRESPNITDRWILSFMQSLIGFFETEMAAYRLYTVV 720 RFLIQNVLRLQKEEEIEFLYNENTVRESPNITDRWILSFMQSLIGFFETEMAAYRLYTVV Sbjct: 661 RFLIQNVLRLQKEEEIEFLYNENTVRESPNITDRWILSFMQSLIGFFETEMAAYRLYTVV 720 Query: 721 PRLVKFVDILTNWYVRMNRRRLKGENGMEDCVMALETLFSVLLSLCRLMAPYTPFLTELM 780 PRLVKFVDILTNWYVRMNRRRLKGENGMEDCVMALETLFSVLLSLCRLMAPYTPFLTELM Sbjct: 721 PRLVKFVDILTNWYVRMNRRRLKGENGMEDCVMALETLFSVLLSLCRLMAPYTPFLTELM 780 Query: 781 YQNLKVLIDPVSVQDKDTLSIHYLMLPRVREELIDKKTESAVSQMQSVIELGRVIRDRKT 840 YQNLKVLIDPVSVQDKDTLSIHYLMLPRVREELIDKKTESAVSQMQSVIELGRVIRDRKT Sbjct: 781 YQNLKVLIDPVSVQDKDTLSIHYLMLPRVREELIDKKTESAVSQMQSVIELGRVIRDRKT 840 Query: 841 IPIKYPLKEIVVIHQDPEALKDIKSLEKYIIEELNVRKVTLSTDKNKYGIRLRAEPDHMV 900 IPIKYPLKEIVVIHQDPEALKDIKSLEKYIIEELNVRKVTLSTDKNKYGIRLRAEPDHMV Sbjct: 841 IPIKYPLKEIVVIHQDPEALKDIKSLEKYIIEELNVRKVTLSTDKNKYGIRLRAEPDHMV 900 Query: 901 LGKRLKGAFKAVMTSIKQLSSEELEQFQKTGTIVVEGHELHDEDIRLMYTFDQATGGTAQ 960 LGKRLKGAFKAVMTSIKQLSSEELEQFQKTGTIVVEGHELHDEDIRLMYTFDQATGGTAQ Sbjct: 901 LGKRLKGAFKAVMTSIKQLSSEELEQFQKTGTIVVEGHELHDEDIRLMYTFDQATGGTAQ 960 Query: 961 FEAHSDAQALVLLDVTPDQSMVDEGMAREVINRIQKLRKKCNLVPTDEITVYYKAKSEGT 1020 FEAHSDAQALVLLDVTPDQSMVDEGMAREVINRIQKLRKKCNLVPTDEITVYYKAKSEGT Sbjct: 961 FEAHSDAQALVLLDVTPDQSMVDEGMAREVINRIQKLRKKCNLVPTDEITVYYKAKSEGT 1020 Query: 1021 YLNSVIESHTEFIFTTIKAPLKPYPVSPSDKVLIQEKTQLKGSELEITLTRGSSLPGPAC 1080 YLNSVIESHTEFIFTTIKAPLKPYPVSPSDKVLIQEKTQLKGSELEITLTRGSSLPGPAC Sbjct: 1021 YLNSVIESHTEFIFTTIKAPLKPYPVSPSDKVLIQEKTQLKGSELEITLTRGSSLPGPAC 1080 Query: 1081 AYVNLNICANGSEQGGVLLLENPKGDNRLDLLKLKSVVTSIFGVKNTELAVFHDETEIQN 1140 AYVNLNICANGSEQGGVLLLENPKGDNRLDLLKLKSVVTSIFGVKNTELAVFHDETEIQN Sbjct: 1081 AYVNLNICANGSEQGGVLLLENPKGDNRLDLLKLKSVVTSIFGVKNTELAVFHDETEIQN 1140 Query: 1141 QTDLLSLSGKTLCVTAGSAPSLINSSSTLLCQYINLQLLNAKPQECLMGTVGTLLLENPL 1200 QTDLLSLSGKTLCVTAGSAPSLINSSSTLLCQYINLQLLNAKPQECLMGTVGTLLLENPL Sbjct: 1141 QTDLLSLSGKTLCVTAGSAPSLINSSSTLLCQYINLQLLNAKPQECLMGTVGTLLLENPL 1200 Query: 1201 GQNGLTHQGLLYEAAKVFGLRSRKLKLFLNETQTQEITEDIPVKTLNMKTVYVSVLPTTA 1260 GQNGLTHQGLLYEAAKVFGLRSRKLKLFLNETQTQEITEDIPVKTLNMKTVYVSVLPTTA Sbjct: 1201 GQNGLTHQGLLYEAAKVFGLRSRKLKLFLNETQTQEITEDIPVKTLNMKTVYVSVLPTTA 1260 Query: 1261 DF 1262 DF Sbjct: 1261 DF 1262 >gi|46852147 mitochondrial isoleucine tRNA synthetase [Homo sapiens] Length = 1012 Score = 282 bits (722), Expect = 1e-75 Identities = 252/878 (28%), Positives = 393/878 (44%), Gaps = 107/878 (12%) Query: 33 KQSKHKPKFTFYDGPPFATGLPHYGHILAGTIKDIVTRYAHQSGFHVDRRFGWDCHGLPV 92 ++ K K +F +DGPP+A G PH GH L +KDI R+ +G + GWDCHGLP+ Sbjct: 101 RERKVKTEFCLHDGPPYANGDPHVGHALNKILKDIANRFHMMNGSKIHFVPGWDCHGLPI 160 Query: 93 EYEIDKTLGIRGPEDVAKMGITEYNNQCRAIVMRYSAEWKSTVSRLGRWIDFDNDYKTLY 152 E ++ LG + + E + R+ + KS R G D++N Y T Sbjct: 161 EIKVLSELG----REAQNLSAMEIRKKARSFAKAAIEKQKSAFIRWGIMADWNNCYYTFD 216 Query: 153 PQFMESVWWVFKQLYDKGLVYRGVKVMPFSTACNTPLSNFESHQNYKDVQDPSVFVTFPL 212 ++ F Q+YDKGLVYR K + +S + T L+ E N + V S++V FPL Sbjct: 217 GKYEAKQLRTFYQMYDKGLVYRSYKPVFWSPSSRTALAEAELEYNPEHV-SRSIYVKFPL 275 Query: 213 -----------EEDETVSLVAWTTTPWTLPSNLAVCVNPEMQYVKIKDVARGRLLILMEA 261 + VS++ WTT PWT+P+N AVC PE +Y +K G L +L Sbjct: 276 LKPSPKLASLIDGSSPVSILVWTTQPWTIPANEAVCYMPESKYAVVKCSKSGDLYVLAAD 335 Query: 262 RLSALYK-LESDYEILERFPGAYLK-GKKYRPLFDYFLKCKENGAFTVLVDNYVKEEEGT 319 +++++ LE+ +E + G L+ G PL + A +L N+V +GT Sbjct: 336 KVASVASTLETTFETISTLSGVDLENGTCSHPLI-------PDKASPLLPANHVTMAKGT 388 Query: 320 GVVHQAPYFGAEDYRVCMDFNIIRKDSLPV-CPVDASGCFTTEVTDFAG------QYVKD 372 G+VH AP G EDY V N LP+ C VD G F TD AG +++ Sbjct: 389 GLVHTAPAHGMEDYGVASQHN------LPMDCLVDEDGVF----TDVAGPELQNKAVLEE 438 Query: 373 ADKSIIRTLKEQGRLLVATTFTHSYPFCWRSDTPLIYKAVPSWFVRVENMVDQLLRNNDL 432 +I+ L+ LL HSYP+ WR+ P++ +A WF+ + D+ Sbjct: 439 GTDVVIKMLQTAKNLLKEEKLVHSYPYDWRTKKPVVIRASKQWFINI----------TDI 488 Query: 433 CYWVPELVREKRF-----GNWLKDARD----WTISRNRYWGTPIPLWVSDDFEEVVCIGS 483 EL+++ +F N + + D W ISR R WG PIP++ +E + Sbjct: 489 KTAAKELLKKVKFIPGSALNGMVEMMDRRPYWCISRQRVWGVPIPVFHHKTKDEYLINSQ 548 Query: 484 VAE-LEELSGAKISDLHRESVDHLTIPSRC-----GKGSLHRI--SEVFDCWFESG-SMP 534 E + +L SD+ +P G +L + ++ D WF+SG S Sbjct: 549 TTEHIVKLVEQHGSDIWWTLPPEQLLPKEVLSEVGGPDALEYVPGQDILDIWFDSGTSWS 608 Query: 535 YAQVHYPFENKREFEDAFPADFIAEGIDQTRGWFYTLLVLATALFGQPPFKNVIVNGLVL 594 Y P ++R AD EG DQ GWF + L+ + A + P+K VIV+G L Sbjct: 609 YV---LPGPDQR-------ADLYLEGKDQLGGWFQSSLLTSVAARKRAPYKTVIVHGFTL 658 Query: 595 ASDGQKMSKRKKN--YPDPV-------SIIQKYGADALRLYLINSPVVRAENLRFKEEGV 645 G+KMSK N +PD V S YGAD LR ++ +S V + V Sbjct: 659 GEKGEKMSKSLGNVIHPDVVVNGGQDQSKEPPYGADVLRWWVADSNVFTEVAI---GPSV 715 Query: 646 RDVLKDVLLPWYNAYRFLIQNVLRLQKEEEIEFLYNENTVRESPNITDRWILSFMQSLIG 705 + +D + N RFL+ NV E ++ + D+++L +Q L Sbjct: 716 LNAARDDISKLRNTLRFLLGNVADFNPE-------TDSIPVNDMYVIDQYMLHLLQDLAN 768 Query: 706 FFETEMAAYRLYTVVPRLVK--FVDILTNWYVRMNRRRLKGENGMEDCVMALET-LFSVL 762 TE+ + V RL++ + L+N+Y + + RL E + + +T L +L Sbjct: 769 KI-TELYKQYDFGKVVRLLRTFYTRELSNFYFSIIKDRLYCEKENDPKRRSCQTALVEIL 827 Query: 763 LSLCRLMAPYTPFLTELMYQNLKVLIDPVSVQDKDTLSIHYLMLPRVREELIDKKTESAV 822 + R AP P L E ++Q++ + +P SV +S + EE ++ Sbjct: 828 DVIVRSFAPILPHLAEEVFQHIPYIKEPKSVFRTGWISTSSIWKKPGLEEAVESACAMRD 887 Query: 823 SQMQSVIELGRVIRDRKTIPIKYP--LKEIVVIHQDPE 858 S + S+ G+ + K I + P L EI+ + Q E Sbjct: 888 SFLGSI--PGKNAAEYKVITVIEPGLLFEIIEMLQSEE 923 >gi|5454158 valyl-tRNA synthetase [Homo sapiens] Length = 1264 Score = 149 bits (375), Expect = 2e-35 Identities = 185/796 (23%), Positives = 319/796 (40%), Gaps = 121/796 (15%) Query: 47 PPFATGLPHYGHILAGTIKDIVTRYAHQSGFHVDRRFGWDCHGLPVEYEIDKTLGIRGPE 106 PP TG H GH L I+D +TR+ G G D G+ + ++K L Sbjct: 343 PPNVTGSLHLGHALTNAIQDSLTRWHRMRGETTLWNPGCDHAGIATQVVVEKKLW----- 397 Query: 107 DVAKMGITEYNNQCRAIVMRYSAEWKST--------VSRLGRWIDFDNDYKTLYPQFMES 158 + G++ + A + +WK + +LG +D+D T+ P+ + Sbjct: 398 --REQGLSRHQLGREAFLQEVW-KWKEEKGDRIYHQLKKLGSSLDWDRACFTMDPKLSAA 454 Query: 159 VWWVFKQLYDKGLVYRGVKVMPFSTACNTPLSNFE------------SHQNYKDVQDPSV 206 V F +L+++G++YR +++ +S N+ +S+ E S YK+ + V Sbjct: 455 VTEAFVRLHEEGIIYRSTRLVNWSCTLNSAISDIEVDKKELTGRTLLSVPGYKEKVEFGV 514 Query: 207 FVTFPLE---EDETVSLVAWTTTPWTLPSNLAVCVNPEMQYVKIKDVARGRLLILMEARL 263 V+F + D +V TT T+ ++AV V+P+ Sbjct: 515 LVSFAYKVQGSDSDEEVVVATTRIETMLGDVAVAVHPK---------------------- 552 Query: 264 SALYKLESDYEILERFPGAYLKGKKYRPLFDYFLKCKENGAFTVLVDNYVKEEEGTGVVH 323 ++ Y+ +LKGK + FL + + ++ D +V + GTG V Sbjct: 553 ------DTRYQ--------HLKGKN---VIHPFL----SRSLPIVFDEFVDMDFGTGAVK 591 Query: 324 QAPYFGAEDYRVCMDFNIIRKDSLPVCPVDASGCFTTEVTDFAGQYVKDADKSIIRTLKE 383 P DY V R + +D+ G F G +A K+++ LKE Sbjct: 592 ITPAHDQNDYEVGQ-----RHGLEAISIMDSRGALINVPPPFLGLPRFEARKAVLVALKE 646 Query: 384 QGRLLVATTFTHSYPFCWRSDTPLIYKAVPSWFVRVENMVDQL---LRNNDLCYWVPELV 440 +G P C RS + P W+VR M + DL +PE Sbjct: 647 RGLFRGIEDNPMVVPLCNRSKDVVEPLLRPQWYVRCGEMAQAASAAVTRGDLRI-LPE-A 704 Query: 441 REKRFGNWLKDARDWTISRNRYWGTPIPLWVSDDFEEVVCIGSVAELEE-LSGAKISDLH 499 ++ + W+ + R+W ISR +WG IP + + V G + +SG ++ Sbjct: 705 HQRTWHAWMDNIREWCISRQLWWGHRIPAYFVTVSDPAVPPGEDPDGRYWVSGRNEAEAR 764 Query: 500 RESVDHLTIPSRCGKGSLHRISEVFDCWFESGSMPYAQVHYPFENKREFEDAFPADFIAE 559 ++ + K SL + +V D WF SG P + + +P +++ + +P + Sbjct: 765 EKAAKEFGVSP--DKISLQQDEDVLDTWFSSGLFPLSILGWPNQSE-DLSVFYPGTLLET 821 Query: 560 GIDQTRGWFYTLLVLATALFGQPPFKNVIVNGLVLASDGQKMSKRKKNYPDPVSIIQKYG 619 G D W +++L L G+ PF+ V ++ +V + G+KMSK N DP+ +I Sbjct: 822 GHDILFFWVARMVMLGLKLTGRLPFREVYLHAIVRDAHGRKMSKSLGNVIDPLDVIYGIS 881 Query: 620 ADALRLYLINSPVVRAENLRFKE-----------EGVRDVLKDVLLPWYNAYRFLIQNVL 668 L L+NS + +E + KE E D L+ L + + R + +V Sbjct: 882 LQGLHNQLLNSNLDPSEVEKAKEGQKADFPAGIPECGTDALRFGLCAYMSQGRDINLDVN 941 Query: 669 R-LQKEEEIEFLYNENTVR---------ESP--------NITDRWILSFMQSLIGFFETE 710 R L L+N SP ++ DRWI S + + Sbjct: 942 RILGYRHFCNKLWNATKFALRGLGKGFVPSPTSQPGGHESLVDRWIRSRLTEAVRLSNQG 1001 Query: 711 MAAYRLYTVVPRLVKF-VDILTNWYVRMNRRRLKG-ENGMEDCVMALETLFSVLLSLCRL 768 AY V F + L + Y+ + L G + +C A +TL++ L RL Sbjct: 1002 FQAYDFPAVTTAQYSFWLYELCDVYLECLKPVLNGVDQVAAEC--ARQTLYTCLDVGLRL 1059 Query: 769 MAPYTPFLTELMYQNL 784 ++P+ PF+TE ++Q L Sbjct: 1060 LSPFMPFVTEELFQRL 1075 >gi|55741845 valyl-tRNA synthetase 2, mitochondrial [Homo sapiens] Length = 1063 Score = 122 bits (307), Expect = 2e-27 Identities = 145/600 (24%), Positives = 232/600 (38%), Gaps = 102/600 (17%) Query: 47 PPFATGLPHYGHILAGTIKDIVTRYAHQSGFHVDRRFGWDCHGLPVEYEIDKTLGIRGPE 106 PP TG H GH L I+D + R+ G V G D G+ + ++K L Sbjct: 145 PPNVTGSLHIGHALTVAIQDALVRWHRMRGDQVLWVPGSDHAGIATQAVVEKQLW----- 199 Query: 107 DVAKMGITEYNNQCRAIVMRYSAEWKST--------VSRLGRWIDFDNDYKTLYPQFMES 158 + G+ + R +R +WK + LG +D+D + T+ + Sbjct: 200 --KERGVRRHELS-REAFLREVWQWKEAKGGEICEQLRALGASLDWDRECFTMDVGSSVA 256 Query: 159 VWWVFKQLYDKGLVYRGVKVMPFSTACNTPLSNFE---------SHQNYKDVQDPSVF-- 207 V F +LY GL+YR +++ +S A + +S+ E + P F Sbjct: 257 VTEAFVRLYKAGLLYRNHQLVNWSCALRSAISDIEVENRPLPGHTQLRLPGCPTPVSFGL 316 Query: 208 ---VTFPLEEDETVSLVAWTTTPWTLPSNLAVCVNPEMQYVKIKDVARGRLLILMEARLS 264 V FP++ + +V TT P TLP ++AV V+P+ Sbjct: 317 LFSVAFPVDGEPDAEVVVGTTRPETLPGDVAVAVHPD----------------------- 353 Query: 265 ALYKLESDYEILERFPGAYLKGKKYR-PLFDYFLKCKENGAFTVLVDNYVKEEEGTGVVH 323 +S Y +L G++ R PL L ++ D V+ GTG V Sbjct: 354 -----DSRY--------THLHGRQLRHPLMGQPLP--------LITDYAVQPHVGTGAVK 392 Query: 324 QAPYFGAEDYRVCMDFNIIRKDSLPVCPVDASGCFTTEVTDFA-GQYVKDADKSIIRTLK 382 P D + R P+ + G T+ D+ G + A + I+ L Sbjct: 393 VTPAHSPADAEMGA-----RHGLSPLNVIAEDGTMTSLCGDWLQGLHRFVAREKIMSVLS 447 Query: 383 EQGRLLVATTFTHSYPFCWRSDTPLIYKAVPSWFVRVENMVDQLLRNNDL-CYWVPELVR 441 E G P C RS + Y WFVR + M + + + + Sbjct: 448 EWGLFRGLQNHPMVLPICSRSGDVIEYLLKNQWFVRCQEMGARAAKAVESGALELSPSFH 507 Query: 442 EKRFGNWLKDARDWTISRNRYWGTPIPLWV-----SDDFEEVVCIG-SVAELEELSGAKI 495 +K + +W DW +SR +WG IP ++ + E+ +G S AE E++ Sbjct: 508 QKNWQHWFSHIGDWCVSRQLWWGHQIPAYLVVEDHAQGEEDCWVVGRSEAEAREVA---- 563 Query: 496 SDLHRESVDHLTIPSRCGKGSLHRISEVFDCWFESGSMPYAQVHYPFENKREFEDAFPAD 555 ++L LT L R +V D WF S P++ + +P E + +P Sbjct: 564 AELTGRPGAELT---------LERDPDVLDTWFSSALFPFSALGWPQETP-DLARFYPLS 613 Query: 556 FIAEGIDQTRGWFYTLLVLATALFGQPPFKNVIVNGLVLASDGQKMSKRKKNYPDPVSII 615 + G D W +++L T L GQ PF V+++ +V G+KMSK N DP II Sbjct: 614 LLETGSDLLLFWVGRMVMLGTQLTGQLPFSKVLLHPMVRDRQGRKMSKSLGNVLDPRDII 673 >gi|7661872 leucyl-tRNA synthetase 2, mitochondrial precursor [Homo sapiens] Length = 903 Score = 65.1 bits (157), Expect = 4e-10 Identities = 47/185 (25%), Positives = 76/185 (41%), Gaps = 22/185 (11%) Query: 11 FPAEEEKILEFWTEFNCFQECLKQS---KHKPKFTFYDGPPFATGLPHYGHILAGTIKDI 67 + + K +E W ++ K S K KPKF P+ +G H GH+ TI D Sbjct: 51 YTLQTRKDVEKWWHQRIKEQASKISEADKSKPKFYVLSMFPYPSGKLHMGHVRVYTISDT 110 Query: 68 VTRYAHQSGFHVDRRFGWDCHGLPVE-YEIDKTLGIRGPEDVAKMGITEYNNQCRAIVMR 126 + R+ G V GWD GLP E +++ L P+ + I Q Sbjct: 111 IARFQKMRGMQVINPMGWDAFGLPAENAAVERNL---HPQSWTQSNIKHMRKQ------- 160 Query: 127 YSAEWKSTVSRLGRWIDFDNDYKTLYPQFMESVWWVFKQLYDKGLVYRGVKVMPFSTACN 186 + RLG +D + T P + + ++F +LY+ GL Y+ ++ + Sbjct: 161 --------LDRLGLCFSWDREITTCLPDYYKWTQYLFIKLYEAGLAYQKEALVNWDPVDQ 212 Query: 187 TPLSN 191 T L+N Sbjct: 213 TVLAN 217 Score = 47.8 bits (112), Expect = 7e-05 Identities = 55/229 (24%), Positives = 83/229 (36%), Gaps = 59/229 (25%) Query: 453 RDWTISRNRYWGTPIPLWVSDDFEEVVCIGSVAELEEL--SGAKISDLHRESVDHLTIPS 510 +DW ISR RYWGTPIP+ VC + LE+L + I+ + L + S Sbjct: 445 KDWLISRQRYWGTPIPI-----VHCPVCGPTPVPLEDLPVTLPNIASFTGKGGPPLAMAS 499 Query: 511 --------RCGKGSLHRISEVFDCWFESG--SMPYAQVHYPFE--NKREFEDAFPADFIA 558 RC KG+ R ++ D + +S Y H P N + P D Sbjct: 500 EWVNCSCPRC-KGAAKRETDTMDTFVDSAWYYFRYTDPHNPHSPFNTAVADYWMPVDLYI 558 Query: 559 EGIDQTRGWFYTLLVLATALFGQ------PPFKNVIVNGLV------------------- 593 G + + + Q PF ++ GL+ Sbjct: 559 GGKEHAVMHLFYARFFSHFCHDQKMVKHREPFHKLLAQGLIKGQTFRLPSGQYLQREEVD 618 Query: 594 --------------LASDGQKMSKRKKNYPDPVSIIQKYGADALRLYLI 628 L +KMSK K N DP ++++YG D +RLY++ Sbjct: 619 LTGSVPVHAKTKEKLEVTWEKMSKSKHNGVDPEEVVEQYGIDTIRLYIL 667 >gi|108773810 leucyl-tRNA synthetase [Homo sapiens] Length = 1176 Score = 40.0 bits (92), Expect = 0.014 Identities = 120/582 (20%), Positives = 206/582 (35%), Gaps = 113/582 (19%) Query: 135 VSRLGRWIDFDNDYKT--LYPQFMESVWWVFKQLYDKGLVYRGVKVMPFSTACNTPLSNF 192 + R+G +D+ + T + P + V W F L ++ + G + +S P + Sbjct: 192 LKRMGLKVDWRRSFITTDVNPYYDSFVRWQFLTLRERNKIKFGKRYTIYSPKDGQPCMDH 251 Query: 193 ESH-------QNYKDVQDPSVFVTFPLE----EDETVSLVAWTTTPWTLPSNLAVCVNPE 241 + Q Y ++ V +P + + + + LVA T P T+ V P+ Sbjct: 252 DRQTGEGVGPQEYTLLK-LKVLEPYPSKLSGLKGKNIFLVAATLRPETMFGQTNCWVRPD 310 Query: 242 MQYVKIKDVARGRLLILMEARLSALY----KLESDYEILERFPGAYLKGKKYR-PLFDYF 296 M+Y+ + V + +A + Y K +++ G + G PL Y Sbjct: 311 MKYIGFETVNGDIFICTQKAARNMSYQGFTKDNGVVPVVKELMGEEILGASLSAPLTSYK 370 Query: 297 LKCKENGAFTVLVDNYVKEEEGTGVVHQAPYFGAEDYRVCMDFN---------------I 341 + VL +KE++GTGVV P +D D + Sbjct: 371 V-------IYVLPMLTIKEDKGTGVVTSVPSDSPDDIAALRDLKKKQALRAKYGIRDDMV 423 Query: 342 IRKDSLPVCPVDASGCFTTE-----------------------------------VTDFA 366 + + +PV + G + V F Sbjct: 424 LPFEPVPVIEIPGFGNLSAVTICDELKIQSQNDREKLAEAKEKIYLKGFYEGIMLVDGFK 483 Query: 367 GQYVKDADKSIIRTLKEQGRLLVATTFTHSYPFCWRSDTPLIYKAVPSWFVRV-----EN 421 GQ V+D K+I + + + G L+ RS + W++ + Sbjct: 484 GQKVQDVKKTIQKKMIDAGDALIY--MEPEKQVMSRSSDECVVALCDQWYLDYGEENWKK 541 Query: 422 MVDQLLRNNDLCYWVPELVREKRFGNWLKDARDWTISRNRYWGTPIPL---WVSDDFEE- 477 Q L+N + E G WL++ SR GT +P W+ + + Sbjct: 542 QTSQCLKNLETFCEETRRNFEATLG-WLQEH---ACSRTYGLGTHLPWDEQWLIESLSDS 597 Query: 478 --VVCIGSVAELEELSGAKISDLHRESVDHLTI-PSRCGKGSLHRISEVFD-CWFESGSM 533 + +VA L L G +LH ++ L I P + K EV+D +F+ Sbjct: 598 TIYMAFYTVAHL--LQGG---NLHGQAESPLGIRPQQMTK-------EVWDYVFFKEAPF 645 Query: 534 PYAQVHYPF--ENKREFEDAFPADFIAEGIDQTRGWFYTLLVLATALFGQPPFK---NVI 588 P Q+ + K+EFE +P D G D L A++ + K V Sbjct: 646 PKTQIAKEKLDQLKQEFEFWYPVDLRVSGKDLVPNHLSYYLYNHVAMWPEQSDKWPTAVR 705 Query: 589 VNGLVLASDGQKMSKRKKNYPDPVSIIQKYGADALRLYLINS 630 NG +L + +KMSK N+ I K+ AD +RL L ++ Sbjct: 706 ANGHLLLNS-EKMSKSTGNFLTLTQAIDKFSADGMRLALADA 746 >gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens] Length = 1946 Score = 37.0 bits (84), Expect = 0.12 Identities = 35/174 (20%), Positives = 81/174 (46%), Gaps = 8/174 (4%) Query: 864 KSLEK--YIIEELNVRKVTLSTDKNKYGIRLRAEPDHMV-LGKRLKGAFKA---VMTSIK 917 K+LEK + EEL ++V+L+ +KN ++L+AE + + + ++ + K+ + +K Sbjct: 873 KALEKSEFQREELKAKQVSLTQEKNDLILQLQAEQETLANVEEQCEWLIKSKIQLEARVK 932 Query: 918 QLSSEELEQFQKTGTIVVEGHELHDEDIRLMYTFDQATGGTAQFEAHSDAQALVLLDVTP 977 +LS E+ + + G +L DE L D + E + ++T Sbjct: 933 ELSERVEEEEEINSELTARGRKLEDECFELKKEIDDLETMLVKSEKEKRTTEHKVKNLTE 992 Query: 978 DQSMVDEGMAREVINRIQKLRKKCNLVPTDEITVYYKAKSEGTYLNSVIESHTE 1031 + ++E +++ +NR K+ ++ + D++ + + S + N +E + Sbjct: 993 EVEFLNEDISK--LNRAAKVVQEAHQQTLDDLHMEEEKLSSLSKANLKLEQQVD 1044 >gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo sapiens] Length = 1940 Score = 36.2 bits (82), Expect = 0.20 Identities = 37/200 (18%), Positives = 90/200 (45%), Gaps = 8/200 (4%) Query: 848 KEIVVIHQDPEALKDIKSLEKYIIEELNVRKVTLSTDKNKYGIRLRAEPDHMV-----LG 902 KE+ + ++ + KD + + +EL + VTL +KN ++++AE ++++ Sbjct: 848 KEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAEERCD 907 Query: 903 KRLKGAFKAVMTSIKQLSSEELEQFQKTGTIVVEGHELHDEDIRLMYTFDQATGGTAQFE 962 + +K F+ + IK+++ ++ + + + +L DE L D A+ E Sbjct: 908 QLIKAKFQ-LEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVE 966 Query: 963 AHSDAQALVLLDVTPDQSMVDEGMAREVINRIQKLRKKCNLVPTDEITVYYKAKSEGTYL 1022 A + ++T + S +DE +A+ + R +K ++ + D++ + Sbjct: 967 KEKHATENKVKNLTEELSGLDETIAK--LTREKKALQEAHQQALDDLQAEEDKVNSLNKT 1024 Query: 1023 NSVIESHTEFIFTTIKAPLK 1042 S +E E + ++++ K Sbjct: 1025 KSKLEQQVEDLESSLEQEKK 1044 >gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta [Homo sapiens] Length = 1983 Score = 35.4 bits (80), Expect = 0.35 Identities = 29/145 (20%), Positives = 64/145 (44%), Gaps = 4/145 (2%) Query: 848 KEIVVIHQDPEALKDIKSLEKYIIEELNVRKVTLSTDKNKYGIRLRAEPDHMV-LGKRLK 906 +E+ + + L+ + + +EL V+++ +KN ++L+AE D++ +R Sbjct: 896 EELAALRAELRGLRGALAAAEAKRQELEETHVSITQEKNDLALQLQAEQDNLADAEERCH 955 Query: 907 GAFKAVMT---SIKQLSSEELEQFQKTGTIVVEGHELHDEDIRLMYTFDQATGGTAQFEA 963 K+ + +K+LS ++ + + +L DE L D A+ E Sbjct: 956 LLIKSKVQLEGKVKELSERLEDEEEVNADLAARRRKLEDECTELKKDIDDLKLTLAKAEK 1015 Query: 964 HSDAQALVLLDVTPDQSMVDEGMAR 988 A + ++T + + +DE +AR Sbjct: 1016 EKQATENKVKNLTEEMAALDESVAR 1040 >gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo sapiens] Length = 1938 Score = 35.0 bits (79), Expect = 0.45 Identities = 32/188 (17%), Positives = 88/188 (46%), Gaps = 6/188 (3%) Query: 848 KEIVVIHQDPEALKDIKSLEKYIIEELNVRKVTLSTDKNKYGIRLRAEPDHMV-LGKRLK 906 KE+ + +D E K+ + + +EL + V+L +KN +++++E ++++ +R + Sbjct: 851 KEMATMKEDFERTKEELARSEARRKELEEKMVSLLQEKNDLQLQVQSETENLMDAEERCE 910 Query: 907 GAFKA---VMTSIKQLSSEELEQFQKTGTIVVEGHELHDEDIRLMYTFDQATGGTAQFEA 963 G K+ + +K+L+ E+ + +V + L D+ L D + E Sbjct: 911 GLIKSKILLEAKVKELTERLEEEEEMNSELVAKKRNLEDKCSSLKRDIDDLELTLTKVEK 970 Query: 964 HSDAQALVLLDVTPDQSMVDEGMAREVINRIQKLRKKCNLVPTDEITVYYKAKSEGTYLN 1023 A + +++ + + ++E +++ + + +K ++ + D++ V + +N Sbjct: 971 EKHATENKVKNLSEEMTALEENISK--LTKEKKSLQEAHQQTLDDLQVEEDKVNGLIKIN 1028 Query: 1024 SVIESHTE 1031 + +E T+ Sbjct: 1029 AKLEQQTD 1036 >gi|38569430 activating transcription factor 7 interacting protein 2 [Homo sapiens] Length = 682 Score = 34.7 bits (78), Expect = 0.59 Identities = 33/129 (25%), Positives = 51/129 (39%), Gaps = 12/129 (9%) Query: 1115 KSVVTSIFGVKNTELAVFHDETEIQNQTDLLSLSGKTLC------VTAGSAPSLINSSST 1168 +S VTS G K T+ VFH ET +++ S LC V P+L+NS ++ Sbjct: 182 ESTVTSTVGDKKTDQMVFHLETNSNSESHDKRQSDNILCSEDSGFVPVEKTPNLVNSVTS 241 Query: 1169 LLCQYINLQLLNAKPQECLMGTVGTLLLENPLGQNGL-THQGLLYEAAKVFGLRSRKLKL 1227 C L K EC ++ + Q+ L T+ Y+ ++F +K Sbjct: 242 NNCADDIL-----KTDECSRTSISNCESADSTWQSSLDTNNNSHYQKKRMFSENEENVKR 296 Query: 1228 FLNETQTQE 1236 Q E Sbjct: 297 MKTSEQINE 305 >gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens] Length = 1684 Score = 34.3 bits (77), Expect = 0.77 Identities = 35/142 (24%), Positives = 65/142 (45%), Gaps = 19/142 (13%) Query: 812 ELIDKKTESAVSQMQSVIELGRVIRD------RKTIPIKYPLKEIVVIHQDPEALKD-IK 864 EL+ K + + + R++++ K I+ +EI + Q E L++ I Sbjct: 1146 ELVKKDAQQTTLMNMEIADYERLMKELNQKLTNKNNKIEDLEQEIKIQKQKQETLQEEIT 1205 Query: 865 SLEKYI--IEELNVR-KVTLSTDKNKYGIRLRAEPDHMVLGKRLKGAFKAVMTSIKQLSS 921 SL+ + EE N + K L K + +AE DH++L LKG +A S Sbjct: 1206 SLQSSVQQYEEKNTKIKQLLVKTKKELADSKQAETDHLILQASLKGELEA--------SQ 1257 Query: 922 EELEQFQ-KTGTIVVEGHELHD 942 +++E ++ + I E H++H+ Sbjct: 1258 QQVEVYKIQLAEITSEKHKIHE 1279 >gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo sapiens] Length = 1937 Score = 34.3 bits (77), Expect = 0.77 Identities = 30/145 (20%), Positives = 66/145 (45%), Gaps = 4/145 (2%) Query: 848 KEIVVIHQDPEALKDIKSLEKYIIEELNVRKVTLSTDKNKYGIRLRAEPDHMV-LGKRLK 906 KE+ + ++ + KD + + +EL + VTL +KN +++++E D + +R + Sbjct: 850 KEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLADAEERCE 909 Query: 907 GAFK---AVMTSIKQLSSEELEQFQKTGTIVVEGHELHDEDIRLMYTFDQATGGTAQFEA 963 K + IK+++ E+ + + + +L DE L D A+ E Sbjct: 910 QLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEK 969 Query: 964 HSDAQALVLLDVTPDQSMVDEGMAR 988 A + ++T + + +DE +A+ Sbjct: 970 EKHATENKVKNLTEEMAGLDETIAK 994 >gi|28269672 serologically defined colon cancer antigen 8 [Homo sapiens] Length = 713 Score = 34.3 bits (77), Expect = 0.77 Identities = 34/143 (23%), Positives = 61/143 (42%), Gaps = 14/143 (9%) Query: 855 QDPEALKDIKSLEKYIIEELNVRKVTLSTDKNKYGIRLRAEPDHMVLGKRLKGAFKAVMT 914 Q EA D E+Y+ L T +N + +L+ E L K+L+ + + Sbjct: 572 QQMEAQHDKTENEQYL----------LLTSQNTFLTKLKEEC--CTLAKKLEQISQKTRS 619 Query: 915 SIKQLSSEELEQFQKTGTIVVEGHELHDEDIRLMYTFDQATGGTAQFEAHSD--AQALVL 972 I QLS E+ + K G + EL ++ ++ + Q + HS AQ LV Sbjct: 620 EIAQLSQEKRYTYDKLGKLQRRNEELEEQCVQHGRVHETMKQRLRQLDKHSQATAQQLVQ 679 Query: 973 LDVTPDQSMVDEGMAREVINRIQ 995 L +Q +++ E ++R++ Sbjct: 680 LLSKQNQLLLERQSLSEEVDRLR 702 >gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo sapiens] Length = 1941 Score = 33.1 bits (74), Expect = 1.7 Identities = 29/145 (20%), Positives = 66/145 (45%), Gaps = 4/145 (2%) Query: 848 KEIVVIHQDPEALKDIKSLEKYIIEELNVRKVTLSTDKNKYGIRLRAEPDHMV-LGKRLK 906 KE+ + ++ + +KD + + +EL + VTL +KN ++++AE + + +R Sbjct: 853 KEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCD 912 Query: 907 GAFKA---VMTSIKQLSSEELEQFQKTGTIVVEGHELHDEDIRLMYTFDQATGGTAQFEA 963 K + IK+++ ++ + + + +L DE L D A+ E Sbjct: 913 QLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEK 972 Query: 964 HSDAQALVLLDVTPDQSMVDEGMAR 988 A + ++T + + +DE +A+ Sbjct: 973 EKHATENKVKNLTEEMAGLDETIAK 997 >gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo sapiens] Length = 1941 Score = 33.1 bits (74), Expect = 1.7 Identities = 29/145 (20%), Positives = 66/145 (45%), Gaps = 4/145 (2%) Query: 848 KEIVVIHQDPEALKDIKSLEKYIIEELNVRKVTLSTDKNKYGIRLRAEPDHMV-LGKRLK 906 KE+ + ++ + +KD + + +EL + VTL +KN ++++AE + + +R Sbjct: 853 KEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCD 912 Query: 907 GAFKA---VMTSIKQLSSEELEQFQKTGTIVVEGHELHDEDIRLMYTFDQATGGTAQFEA 963 K + IK+++ ++ + + + +L DE L D A+ E Sbjct: 913 QLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEK 972 Query: 964 HSDAQALVLLDVTPDQSMVDEGMAR 988 A + ++T + + +DE +A+ Sbjct: 973 EKHATENKVKNLTEEMAGLDETIAK 997 >gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo sapiens] Length = 1939 Score = 32.3 bits (72), Expect = 2.9 Identities = 30/145 (20%), Positives = 65/145 (44%), Gaps = 4/145 (2%) Query: 848 KEIVVIHQDPEALKDIKSLEKYIIEELNVRKVTLSTDKNKYGIRLRAEPDHMV-LGKRLK 906 KE+ + ++ E K+ + + +EL + VTL +KN ++++AE D + +R Sbjct: 851 KEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADSLADAEERCD 910 Query: 907 GAFKA---VMTSIKQLSSEELEQFQKTGTIVVEGHELHDEDIRLMYTFDQATGGTAQFEA 963 K + IK+++ ++ + + + +L DE L D A+ E Sbjct: 911 QLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEK 970 Query: 964 HSDAQALVLLDVTPDQSMVDEGMAR 988 A + ++T + + +DE +A+ Sbjct: 971 EKHATENKVKNLTEEMAGLDETIAK 995 >gi|139394579 zinc finger and BTB domain containing 40 [Homo sapiens] Length = 1239 Score = 32.3 bits (72), Expect = 2.9 Identities = 13/27 (48%), Positives = 22/27 (81%) Query: 1043 PYPVSPSDKVLIQEKTQLKGSELEITL 1069 P PV+P+++V+ E+TQL GS++ +TL Sbjct: 1180 PEPVAPTEQVITLEETQLAGSQVFVTL 1206 >gi|139394556 zinc finger and BTB domain containing 40 [Homo sapiens] Length = 1239 Score = 32.3 bits (72), Expect = 2.9 Identities = 13/27 (48%), Positives = 22/27 (81%) Query: 1043 PYPVSPSDKVLIQEKTQLKGSELEITL 1069 P PV+P+++V+ E+TQL GS++ +TL Sbjct: 1180 PEPVAPTEQVITLEETQLAGSQVFVTL 1206 >gi|221219020 NYD-SP11 protein [Homo sapiens] Length = 2873 Score = 32.0 bits (71), Expect = 3.8 Identities = 38/165 (23%), Positives = 77/165 (46%), Gaps = 15/165 (9%) Query: 793 VQDKDTLSIHYLMLP-------RVREELIDKKTESAVSQMQSVIELGRVIRDRKTIPIKY 845 +Q+K+ L+ H +P R RE+LI+KK + A + + + + + +++ + K Sbjct: 1778 IQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQKRERWINSMEELTKNKMILYQKK 1837 Query: 846 PL-KEIVVIHQDPEALKDIKSLEKYIIEELNVRKVTLSTDKNKYGI--RLRAEPDHMVLG 902 L +E + Q+ E L K Y E L K L KNK G+ ++ A+ + Sbjct: 1838 NLAQEKKNLAQEKEKLAQRKENLLYNKERLTHSKKQLVQVKNKLGMFNKILAQVE----- 1892 Query: 903 KRLKGAFKAVMTSIKQLSSEELEQFQKTGTIVVEGHELHDEDIRL 947 ++L + V+ ++L+ E + Q ++ + +L E ++L Sbjct: 1893 EKLTQEKETVIKKKEKLAETEKKLVQVEDSLAKKQEKLAQEKMKL 1937 >gi|156104874 envoplakin [Homo sapiens] Length = 2033 Score = 32.0 bits (71), Expect = 3.8 Identities = 25/86 (29%), Positives = 46/86 (53%), Gaps = 9/86 (10%) Query: 816 KKTESAVSQMQSVIE-LGRVIRDRKTIPIKYPLKEIVVIHQDPEALKDIKSLEKYIIEEL 874 K+ E AV+++Q+ IE L R I ++ K +KE+ + QDP L++ L + ++EE Sbjct: 1107 KQAEEAVAKLQARIEDLERAI---SSVEPKVIVKEVKKVEQDPGLLQESSRL-RSLLEEE 1162 Query: 875 NVRKVTLSTD----KNKYGIRLRAEP 896 + TL+ + +KY + + P Sbjct: 1163 RTKNATLARELSDLHSKYSVVEKQRP 1188 >gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo sapiens] Length = 1939 Score = 32.0 bits (71), Expect = 3.8 Identities = 30/145 (20%), Positives = 65/145 (44%), Gaps = 4/145 (2%) Query: 848 KEIVVIHQDPEALKDIKSLEKYIIEELNVRKVTLSTDKNKYGIRLRAEPDHMV-LGKRLK 906 KE+ + ++ E K+ + + +EL + VTL +KN ++++AE D + +R Sbjct: 851 KEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADALADAEERCD 910 Query: 907 GAFKA---VMTSIKQLSSEELEQFQKTGTIVVEGHELHDEDIRLMYTFDQATGGTAQFEA 963 K + IK+++ ++ + + + +L DE L D A+ E Sbjct: 911 QLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEK 970 Query: 964 HSDAQALVLLDVTPDQSMVDEGMAR 988 A + ++T + + +DE +A+ Sbjct: 971 EKHATENKVKNLTEEMAGLDETIAK 995 >gi|148806872 lupus brain antigen 1 [Homo sapiens] Length = 2375 Score = 32.0 bits (71), Expect = 3.8 Identities = 19/55 (34%), Positives = 28/55 (50%), Gaps = 6/55 (10%) Query: 650 KDVLLPWYNAYRFLIQNVLRLQKEEEIEFLYNENTVRESPNITDRWILSFMQSLI 704 K++L P Y ++RF R +E I FL+ + R TD W LS MQ+ + Sbjct: 1696 KEILKPNYKSFRFY-----RFALKEYIHFLFENESARNRRESTDLW-LSAMQAFL 1744 >gi|114326455 chromodomain helicase DNA binding protein 8 [Homo sapiens] Length = 2302 Score = 31.6 bits (70), Expect = 5.0 Identities = 24/87 (27%), Positives = 44/87 (50%), Gaps = 15/87 (17%) Query: 902 GKRLKGAFK--AVMTSIKQLSSE--ELEQFQKTGTIVVEGHELHDEDIRLMYTFDQATGG 957 G+ + GA+K A++T+ + + S+ EL + + I+ E H L + + +L+ + Sbjct: 632 GRLIPGAYKFDALITTFEMILSDCPELREIEWRCVIIDEAHRLKNRNCKLLDSLK----- 686 Query: 958 TAQFEAHSDAQALVLLDVTPDQSMVDE 984 H D + VLL TP Q+ V+E Sbjct: 687 ------HMDLEHKVLLTGTPLQNTVEE 707 >gi|21359963 ring finger and WD repeat domain 2 isoform a [Homo sapiens] Length = 731 Score = 31.2 bits (69), Expect = 6.5 Identities = 23/86 (26%), Positives = 45/86 (52%), Gaps = 6/86 (6%) Query: 795 DKDTLSIHYLMLPRVREELIDKK----TESAVSQMQSVIELGRVIRDRKTIPIKYPLKEI 850 D+D L + + L + E L+ KK ES +Q+Q ++E +V R K ++ KE+ Sbjct: 229 DQDNLDLANVNL--MLELLVQKKKQLEAESHAAQLQILMEFLKVARRNKREQLEQIQKEL 286 Query: 851 VVIHQDPEALKDIKSLEKYIIEELNV 876 V+ +D + ++++ L + E+ V Sbjct: 287 SVLEEDIKRVEEMSGLYSPVSEDSTV 312 >gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo sapiens] Length = 1935 Score = 30.8 bits (68), Expect = 8.5 Identities = 28/145 (19%), Positives = 65/145 (44%), Gaps = 4/145 (2%) Query: 848 KEIVVIHQDPEALKDIKSLEKYIIEELNVRKVTLSTDKNKYGIRLRAEPDHMV-LGKRLK 906 KE+ + ++ LK+ + +EL + V+L +KN ++++AE D++ +R Sbjct: 847 KEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCD 906 Query: 907 GAFK---AVMTSIKQLSSEELEQFQKTGTIVVEGHELHDEDIRLMYTFDQATGGTAQFEA 963 K + +K+++ ++ + + + +L DE L D A+ E Sbjct: 907 QLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEK 966 Query: 964 HSDAQALVLLDVTPDQSMVDEGMAR 988 A + ++T + + +DE +A+ Sbjct: 967 EKHATENKVKNLTEEMAGLDEIIAK 991 >gi|14043022 methionyl-tRNA synthetase [Homo sapiens] Length = 900 Score = 30.8 bits (68), Expect = 8.5 Identities = 22/73 (30%), Positives = 37/73 (50%), Gaps = 9/73 (12%) Query: 408 IYKAVPSWFVRVENMVDQLLRNNDLCYWVPELVREKRFGNWLKDA-RDWTISRNRYWGTP 466 ++ +P R+E + + L +D W P R +WL+D + I+R+ WGTP Sbjct: 450 LFLDLPKLEKRLEEWLGRTLPGSD---WTPNAQFITR--SWLRDGLKPRCITRDLKWGTP 504 Query: 467 IPLWVSDDFEEVV 479 +PL + FE+ V Sbjct: 505 VPL---EGFEDKV 514 >gi|24308436 methionine-tRNA synthetase 2 precursor [Homo sapiens] Length = 593 Score = 30.8 bits (68), Expect = 8.5 Identities = 14/35 (40%), Positives = 19/35 (54%) Query: 598 GQKMSKRKKNYPDPVSIIQKYGADALRLYLINSPV 632 GQKMSK N DP + + +Y D R +L+ V Sbjct: 345 GQKMSKSLGNVVDPRTCLNRYTVDGFRYFLLRQGV 379 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.320 0.137 0.411 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 47,171,141 Number of Sequences: 37866 Number of extensions: 2139247 Number of successful extensions: 4331 Number of sequences better than 10.0: 29 Number of HSP's better than 10.0 without gapping: 10 Number of HSP's successfully gapped in prelim test: 19 Number of HSP's that attempted gapping in prelim test: 4269 Number of HSP's gapped (non-prelim): 55 length of query: 1262 length of database: 18,247,518 effective HSP length: 114 effective length of query: 1148 effective length of database: 13,930,794 effective search space: 15992551512 effective search space used: 15992551512 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.