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Search of human proteins with 92859701
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|92859701 myosin VI [Homo sapiens]
(1285 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|92859701 myosin VI [Homo sapiens] 2580 0.0
gi|154354979 myosin X [Homo sapiens] 518 e-146
gi|122937345 myosin VB [Homo sapiens] 497 e-140
gi|215982794 myosin VA isoform 2 [Homo sapiens] 496 e-140
gi|215982791 myosin VA isoform 1 [Homo sapiens] 496 e-140
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 494 e-139
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 490 e-138
gi|153945715 myosin VC [Homo sapiens] 484 e-136
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 480 e-135
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 480 e-135
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 478 e-134
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 478 e-134
gi|189083802 myosin VIIA isoform 2 [Homo sapiens] 473 e-133
gi|189083800 myosin VIIA isoform 3 [Homo sapiens] 473 e-133
gi|189083798 myosin VIIA isoform 1 [Homo sapiens] 473 e-133
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [... 456 e-128
gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens] 455 e-127
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H... 455 e-127
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo... 454 e-127
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo... 454 e-127
gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens] 453 e-127
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo... 450 e-126
gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo ... 448 e-125
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s... 443 e-124
gi|156104908 myosin heavy chain 6 [Homo sapiens] 441 e-123
gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta ... 441 e-123
gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens] 440 e-123
gi|118402590 myosin XV [Homo sapiens] 438 e-122
gi|194328685 myosin IB isoform 1 [Homo sapiens] 433 e-121
gi|44889481 myosin IB isoform 2 [Homo sapiens] 433 e-121
>gi|92859701 myosin VI [Homo sapiens]
Length = 1285
Score = 2580 bits (6686), Expect = 0.0
Identities = 1285/1285 (100%), Positives = 1285/1285 (100%)
Query: 1 MEDGKPVWAPHPTDGFQMGNIVDIGPDSLTIEPLNQKGKTFLALINQVFPAEEDSKKDVE 60
MEDGKPVWAPHPTDGFQMGNIVDIGPDSLTIEPLNQKGKTFLALINQVFPAEEDSKKDVE
Sbjct: 1 MEDGKPVWAPHPTDGFQMGNIVDIGPDSLTIEPLNQKGKTFLALINQVFPAEEDSKKDVE 60
Query: 61 DNCSLMYLNEATLLHNIKVRYSKDRIYTYVANILIAVNPYFDIPKIYSSEAIKSYQGKSL 120
DNCSLMYLNEATLLHNIKVRYSKDRIYTYVANILIAVNPYFDIPKIYSSEAIKSYQGKSL
Sbjct: 61 DNCSLMYLNEATLLHNIKVRYSKDRIYTYVANILIAVNPYFDIPKIYSSEAIKSYQGKSL 120
Query: 121 GTRPPHVFAIADKAFRDMKVLKMSQSIIVSGESGAGKTENTKFVLRYLTESYGTGQDIDD 180
GTRPPHVFAIADKAFRDMKVLKMSQSIIVSGESGAGKTENTKFVLRYLTESYGTGQDIDD
Sbjct: 121 GTRPPHVFAIADKAFRDMKVLKMSQSIIVSGESGAGKTENTKFVLRYLTESYGTGQDIDD 180
Query: 181 RIVEANPLLEAFGNAKTVRNNNSSRFGKFVEIHFNEKSSVVGGFVSHYLLEKSRICVQGK 240
RIVEANPLLEAFGNAKTVRNNNSSRFGKFVEIHFNEKSSVVGGFVSHYLLEKSRICVQGK
Sbjct: 181 RIVEANPLLEAFGNAKTVRNNNSSRFGKFVEIHFNEKSSVVGGFVSHYLLEKSRICVQGK 240
Query: 241 EERNYHIFYRLCAGASEDIREKLHLSSPDNFRYLNRGCTRYFANKETDKQILQNRKSPEY 300
EERNYHIFYRLCAGASEDIREKLHLSSPDNFRYLNRGCTRYFANKETDKQILQNRKSPEY
Sbjct: 241 EERNYHIFYRLCAGASEDIREKLHLSSPDNFRYLNRGCTRYFANKETDKQILQNRKSPEY 300
Query: 301 LKAGSMKDPLLDDHGDFIRMCTAMKKIGLDDEEKLDLFRVVAGVLHLGNIDFEEAGSTSG 360
LKAGSMKDPLLDDHGDFIRMCTAMKKIGLDDEEKLDLFRVVAGVLHLGNIDFEEAGSTSG
Sbjct: 301 LKAGSMKDPLLDDHGDFIRMCTAMKKIGLDDEEKLDLFRVVAGVLHLGNIDFEEAGSTSG 360
Query: 361 GCNLKNKSAQSLEYCAELLGLDQDDLRVSLTTRVMLTTAGGTKGTVIKVPLKVEQANNAR 420
GCNLKNKSAQSLEYCAELLGLDQDDLRVSLTTRVMLTTAGGTKGTVIKVPLKVEQANNAR
Sbjct: 361 GCNLKNKSAQSLEYCAELLGLDQDDLRVSLTTRVMLTTAGGTKGTVIKVPLKVEQANNAR 420
Query: 421 DALAKTVYSHLFDHVVNRVNQCFPFETSSYFIGVLDIAGFEYFEHNSFEQFCINYCNEKL 480
DALAKTVYSHLFDHVVNRVNQCFPFETSSYFIGVLDIAGFEYFEHNSFEQFCINYCNEKL
Sbjct: 421 DALAKTVYSHLFDHVVNRVNQCFPFETSSYFIGVLDIAGFEYFEHNSFEQFCINYCNEKL 480
Query: 481 QQFFNERILKEEQELYQKEGLGVNEVHYVDNQDCIDLIEAKLVGILDILDEENRLPQPSD 540
QQFFNERILKEEQELYQKEGLGVNEVHYVDNQDCIDLIEAKLVGILDILDEENRLPQPSD
Sbjct: 481 QQFFNERILKEEQELYQKEGLGVNEVHYVDNQDCIDLIEAKLVGILDILDEENRLPQPSD 540
Query: 541 QHFTSAVHQKHKDHFRLTIPRKSKLAVHRNIRDDEGFIIRHFAGAVCYETTQFVEKNNDA 600
QHFTSAVHQKHKDHFRLTIPRKSKLAVHRNIRDDEGFIIRHFAGAVCYETTQFVEKNNDA
Sbjct: 541 QHFTSAVHQKHKDHFRLTIPRKSKLAVHRNIRDDEGFIIRHFAGAVCYETTQFVEKNNDA 600
Query: 601 LHMSLESLICESRDKFIRELFESSTNNNKDTKQKAGKLSFISVGNKFKTQLNLLLDKLRS 660
LHMSLESLICESRDKFIRELFESSTNNNKDTKQKAGKLSFISVGNKFKTQLNLLLDKLRS
Sbjct: 601 LHMSLESLICESRDKFIRELFESSTNNNKDTKQKAGKLSFISVGNKFKTQLNLLLDKLRS 660
Query: 661 TGASFIRCIKPNLKMTSHHFEGAQILSQLQCSGMVSVLDLMQGGYPSRASFHELYNMYKK 720
TGASFIRCIKPNLKMTSHHFEGAQILSQLQCSGMVSVLDLMQGGYPSRASFHELYNMYKK
Sbjct: 661 TGASFIRCIKPNLKMTSHHFEGAQILSQLQCSGMVSVLDLMQGGYPSRASFHELYNMYKK 720
Query: 721 YMPDKLARLDPRLFCKALFKALGLNENDYKFGLTKVFFRPGKFAEFDQIMKSDPDHLAEL 780
YMPDKLARLDPRLFCKALFKALGLNENDYKFGLTKVFFRPGKFAEFDQIMKSDPDHLAEL
Sbjct: 721 YMPDKLARLDPRLFCKALFKALGLNENDYKFGLTKVFFRPGKFAEFDQIMKSDPDHLAEL 780
Query: 781 VKRVNHWLTCSRWKKVQWCSLSVIKLKNKIKYRAEACIKMQKTIRMWLCKRRHKPRIDGL 840
VKRVNHWLTCSRWKKVQWCSLSVIKLKNKIKYRAEACIKMQKTIRMWLCKRRHKPRIDGL
Sbjct: 781 VKRVNHWLTCSRWKKVQWCSLSVIKLKNKIKYRAEACIKMQKTIRMWLCKRRHKPRIDGL 840
Query: 841 VKVGTLKKRLDKFNEVVSVLKDGKPEMNKQIKNLEISIDTLMAKIKSTMMTQEQIQKEYD 900
VKVGTLKKRLDKFNEVVSVLKDGKPEMNKQIKNLEISIDTLMAKIKSTMMTQEQIQKEYD
Sbjct: 841 VKVGTLKKRLDKFNEVVSVLKDGKPEMNKQIKNLEISIDTLMAKIKSTMMTQEQIQKEYD 900
Query: 901 ALVKSSEELLSALQKKKQQEEEAERLRRIQEEMEKERKRREEDEKRRRKEEEERRMKLEM 960
ALVKSSEELLSALQKKKQQEEEAERLRRIQEEMEKERKRREEDEKRRRKEEEERRMKLEM
Sbjct: 901 ALVKSSEELLSALQKKKQQEEEAERLRRIQEEMEKERKRREEDEKRRRKEEEERRMKLEM 960
Query: 961 EAKRKQEEEERKKREDDEKRIQAEVEAQLARQKEEESQQQAVLEQERRDRELALRIAQSE 1020
EAKRKQEEEERKKREDDEKRIQAEVEAQLARQKEEESQQQAVLEQERRDRELALRIAQSE
Sbjct: 961 EAKRKQEEEERKKREDDEKRIQAEVEAQLARQKEEESQQQAVLEQERRDRELALRIAQSE 1020
Query: 1021 AELISDEAQADLALRRNDGTRPKMTPEQMAKEMSEFLSRGPAVLATKAAAGTKKYDLSKW 1080
AELISDEAQADLALRRNDGTRPKMTPEQMAKEMSEFLSRGPAVLATKAAAGTKKYDLSKW
Sbjct: 1021 AELISDEAQADLALRRNDGTRPKMTPEQMAKEMSEFLSRGPAVLATKAAAGTKKYDLSKW 1080
Query: 1081 KYAELRDTINTSCDIELLAACREEFHRRLKVYHAWKSKNKKRNTETEQRAPKSVTDYDFA 1140
KYAELRDTINTSCDIELLAACREEFHRRLKVYHAWKSKNKKRNTETEQRAPKSVTDYDFA
Sbjct: 1081 KYAELRDTINTSCDIELLAACREEFHRRLKVYHAWKSKNKKRNTETEQRAPKSVTDYDFA 1140
Query: 1141 PFLNNSPQQNPAAQIPARQREIEMNRQQRFFRIPFIRPADQYKDPQSKKKGWWYAHFDGP 1200
PFLNNSPQQNPAAQIPARQREIEMNRQQRFFRIPFIRPADQYKDPQSKKKGWWYAHFDGP
Sbjct: 1141 PFLNNSPQQNPAAQIPARQREIEMNRQQRFFRIPFIRPADQYKDPQSKKKGWWYAHFDGP 1200
Query: 1201 WIARQMELHPDKPPILLVAGKDDMEMCELNLEETGLTRKRGAEILPRQFEEIWERCGGIQ 1260
WIARQMELHPDKPPILLVAGKDDMEMCELNLEETGLTRKRGAEILPRQFEEIWERCGGIQ
Sbjct: 1201 WIARQMELHPDKPPILLVAGKDDMEMCELNLEETGLTRKRGAEILPRQFEEIWERCGGIQ 1260
Query: 1261 YLQNAIESRQARPTYATAMLQSLLK 1285
YLQNAIESRQARPTYATAMLQSLLK
Sbjct: 1261 YLQNAIESRQARPTYATAMLQSLLK 1285
>gi|154354979 myosin X [Homo sapiens]
Length = 2058
Score = 518 bits (1335), Expect = e-146
Identities = 339/1002 (33%), Positives = 538/1002 (53%), Gaps = 147/1002 (14%)
Query: 55 SKKDVEDNCSLMYLNEATLLHNIKVRYSKDRIYTYVANILIAVNPYFDIPKIYSSEAIKS 114
+++ V+D SL L+ ++++N+ RY +++IYTY+ +IL +VNPY I +Y ++
Sbjct: 61 NEEGVDDMASLTELHGGSIMYNLFQRYKRNQIYTYIGSILASVNPYQPIAGLYEPATMEQ 120
Query: 115 YQGKSLGTRPPHVFAIADKAFRDMKVLKMSQSIIVSGESGAGKTENTKFVLRYLTESYGT 174
Y + LG PPH+FAIA++ +R + +Q I++SGESGAGKTE+TK +L++L+
Sbjct: 121 YSRRHLGELPPHIFAIANECYRCLWKRHDNQCILISGESGAGKTESTKLILKFLSVISQQ 180
Query: 175 GQD---------IDDRIVEANPLLEAFGNAKTVRNNNSSRFGKFVEIHFNEKSSVVGGFV 225
+ ++ I+E++P++EAFGNAKTV NNNSSRFGKFV+++ +K ++ GG +
Sbjct: 181 SLELSLKEKTSCVERAILESSPIMEAFGNAKTVYNNNSSRFGKFVQLNICQKGNIQGGRI 240
Query: 226 SHYLLEKSRICVQGKEERNYHIFYRLCAGASEDIREKLHLSSPDNFRYLNRGCTRYFANK 285
YLLEK+R+ Q ERNYHIFY L AG + RE+ +LS+P+N+ YLN+
Sbjct: 241 VDYLLEKNRVVRQNPGERNYHIFYALLAGLEHEEREEFYLSTPENYHYLNQ--------- 291
Query: 286 ETDKQILQNRKSPEYLKAGSMKDPLLDDHGDFIRMCTAMKKIGLDDEEKLDLFRVVAGVL 345
+G ++D + D F + TAM + EE ++ R++AG+L
Sbjct: 292 -----------------SGCVEDKTISDQESFREVITAMDVMQFSKEEVREVSRLLAGIL 334
Query: 346 HLGNIDFEEAGSTSGGCNLKNKSAQSLEYCAELLGLDQDDLRVSLTTRVMLTTAGGTKGT 405
HLGNI+F T+GG + K+A L AELLGLD L +LT R M +G
Sbjct: 335 HLGNIEF----ITAGGAQVSFKTA--LGRSAELLGLDPTQLTDALTQRSMFL-----RGE 383
Query: 406 VIKVPLKVEQANNARDALAKTVYSHLFDHVVNRVNQCFPFETSSYFIGVLDIAGFEYFEH 465
I PL V+QA ++RD+LA +Y+ F+ V+ ++N IG+LDI GFE FE
Sbjct: 384 EILTPLNVQQAVDSRDSLAMALYACCFEWVIKKINSRIKGNEDFKSIGILDIFGFENFEV 443
Query: 466 NSFEQFCINYCNEKLQQFFNERILKEEQELYQKEGLGVNEVHYVDNQDCIDLIEAKLVGI 525
N FEQF INY NEKLQ++FN+ I EQ Y +EGL ++ ++DN +C+DLIE KL G+
Sbjct: 444 NHFEQFNINYANEKLQEYFNKHIFSLEQLEYSREGLVWEDIDWIDNGECLDLIEKKL-GL 502
Query: 526 LDILDEENRLPQPSDQHFTSAVHQKH-KDHFRLTIPRKSKLAVHRNIRDDEGFIIRHFAG 584
L +++EE+ PQ +D +H +H +HF + K ++AV+ F ++H+AG
Sbjct: 503 LALINEESHFPQATDSTLLEKLHSQHANNHFYV----KPRVAVNN-------FGVKHYAG 551
Query: 585 AVCYETTQFVEKNNDALHMSLESLICESRDKFIRELFES-STNNNKDTKQKAGKLSFISV 643
V Y+ +EKN D L +L+ ESR FI +LFE S+ NN+DT + K +V
Sbjct: 552 EVQYDVRGILEKNRDTFRDDLLNLLRESRFDFIYDLFEHVSSRNNQDTLKCGSKHRRPTV 611
Query: 644 GNKFKTQLNLLLDKLRSTGASFIRCIKPNLKMTSHHFEGAQILSQLQCSGMVSVLDLMQG 703
++FK L+ L+ L S+ F+RCIKPN++ F+ A +L+QL+ SGM+ + + +
Sbjct: 612 SSQFKDSLHSLMATLSSSNPFFVRCIKPNMQKMPDQFDQAVVLNQLRYSGMLETVRIRKA 671
Query: 704 GYPSRASFHELYNMYKKYMPDKLARLDPRLFCKALFKALGLNENDYKFGLTKVFFRPGKF 763
GY R F + Y YK M + D R C +L + + ++++ G TKVF R
Sbjct: 672 GYAVRRPFQDFYKRYKVLMRNLALPEDVRGKCTSLLQLYDASNSEWQLGKTKVFLRESLE 731
Query: 764 AEFDQIMKSDPDHLAELVK-RVNHWLTCSRWKKVQWCSLSVIKLKNKIKYRAEACIKMQK 822
+ ++ + + H A +++ V +L +++KV +C + + QK
Sbjct: 732 QKLEKRREEEVSHAAMVIRAHVLGFLARKQYRKVLYCVVII-----------------QK 774
Query: 823 TIRMWLCKRRHKPRIDGLVKVGTLKKRLDKFNEVVSVLKDGKPEMNKQIKNLEISIDTLM 882
R +L +RR LK KQ++
Sbjct: 775 NYRAFLLRRRFLH------------------------LKKAAIVFQKQLRG--------- 801
Query: 883 AKIKSTMMTQEQIQKEYDALVKSSEELLSALQKKKQQEEEAERLRRIQEEMEKERKRREE 942
+ ++ Y L+ E Q++K+++EE E+ +R +EE E+ER+RRE
Sbjct: 802 ----------QIARRVYRQLLAEKRE-----QEEKKKQEEEEKKKREEEERERERERREA 846
Query: 943 DEKRRRKEEEERRMKLEMEAKRKQEEEERKKREDDEKRIQAEVEAQLARQKE-------E 995
+ R ++EEE R + E+EA +K ++E RE ++++ +VE L +KE +
Sbjct: 847 E--LRAQQEEETRKQQELEALQKSQKEAELTRELEKQKENKQVEEILRLEKEIEDLQRMK 904
Query: 996 ESQQQAVLE------QERRDREL------ALRIAQSEAELIS 1025
E Q+ ++ E QERRD+EL A R AQ E ++
Sbjct: 905 EQQELSLTEASLQKLQERRDQELRRLEEEACRAAQEFLESLN 946
Score = 61.2 bits (147), Expect = 6e-09
Identities = 41/141 (29%), Positives = 78/141 (55%), Gaps = 2/141 (1%)
Query: 895 IQKEYDALVKSSEEL-LSALQKKKQQEEEAERLRRIQEEMEKERKRREEDEKRRRKEEEE 953
IQK Y A + L L Q++ + RR+ ++ E KR +E++K++ +EE++
Sbjct: 772 IQKNYRAFLLRRRFLHLKKAAIVFQKQLRGQIARRVYRQLLAE-KREQEEKKKQEEEEKK 830
Query: 954 RRMKLEMEAKRKQEEEERKKREDDEKRIQAEVEAQLARQKEEESQQQAVLEQERRDRELA 1013
+R + E E +R++ E E + ++++E R Q E+EA QKE E ++ ++E + E
Sbjct: 831 KREEEERERERERREAELRAQQEEETRKQQELEALQKSQKEAELTRELEKQKENKQVEEI 890
Query: 1014 LRIAQSEAELISDEAQADLAL 1034
LR+ + +L + Q +L+L
Sbjct: 891 LRLEKEIEDLQRMKEQQELSL 911
>gi|122937345 myosin VB [Homo sapiens]
Length = 1848
Score = 497 bits (1280), Expect = e-140
Identities = 336/1082 (31%), Positives = 570/1082 (52%), Gaps = 123/1082 (11%)
Query: 61 DNCSLMYLNEATLLHNIKVRY-SKDRIYTYVANILIAVNPYFDIPKIYSSEAIKSYQGKS 119
D +L YL+E +LHN+KVR+ + IYTY +L+A+NPY +P IY + I +Y G++
Sbjct: 73 DLTALSYLHEPAVLHNLKVRFLESNHIYTYCGIVLVAINPYEQLP-IYGQDVIYTYSGQN 131
Query: 120 LGTRPPHVFAIADKAFRDMKVLKMSQSIIVSGESGAGKTENTKFVLRYLTESYGTGQD-- 177
+G PH+FA+A++A++ M + +QSIIVSGESGAGKT + K+ +RY G+ +
Sbjct: 132 MGDMDPHIFAVAEEAYKQMARDEKNQSIIVSGESGAGKTVSAKYAMRYFATVGGSASETN 191
Query: 178 IDDRIVEANPLLEAFGNAKTVRNNNSSRFGKFVEIHFNEKSSVVGGFVSHYLLEKSRICV 237
I+++++ ++P++EA GNAKT RN+NSSRFGK+++I F+++ ++G + YLLEKSR+
Sbjct: 192 IEEKVLASSPIMEAIGNAKTTRNDNSSRFGKYIQIGFDKRYHIIGANMRTYLLEKSRVVF 251
Query: 238 QGKEERNYHIFYRLCAGASEDIREKLHLSSPDNFRYLNRGCTRYFANKETDKQILQNRKS 297
Q +ERNYHIFY+LCA A ++L L+S ++F Y ++G
Sbjct: 252 QADDERNYHIFYQLCAAAGLPEFKELALTSAEDFFYTSQG-------------------- 291
Query: 298 PEYLKAGSMKDPLLDDHGDFIRMCTAMKKIGLDDEEKLDLFRVVAGVLHLGNIDFEEAGS 357
G +DD DF + A +G+ + ++ +F+++A +LHLG++ + A
Sbjct: 292 ------GDTSIEGVDDAEDFEKTRQAFTLLGVKESHQMSIFKIIASILHLGSVAIQ-AER 344
Query: 358 TSGGCNLKNKSAQSLEYCAELLGLDQDDLRVSLTTRVMLTTAGGTKGTVIKVPLKVEQAN 417
C++ + +C LLG++ + L R ++TT+ T +K + ++Q
Sbjct: 345 DGDSCSISPQDVYLSNFC-RLLGVEHSQMEHWLCHRKLVTTSE----TYVKT-MSLQQVI 398
Query: 418 NARDALAKTVYSHLFDHVVNRVNQCFPFETSSY-FIGVLDIAGFEYFEHNSFEQFCINYC 476
NAR+ALAK +Y+ LF +V +N+ + FIGVLDI GFE FE NSFEQFCINY
Sbjct: 399 NARNALAKHIYAQLFGWIVEHINKALHTSLKQHSFIGVLDIYGFETFEVNSFEQFCINYA 458
Query: 477 NEKLQQFFNERILKEEQELYQKEGLGVNEVHYVDNQDCIDLIEAKLVGILDILDEENRLP 536
NEKLQQ FN + K EQE Y KE + + + DNQ CIDLIEAKL GILD+LDEE ++P
Sbjct: 459 NEKLQQQFNSHVFKLEQEEYMKEQIPWTLIDFYDNQPCIDLIEAKL-GILDLLDEECKVP 517
Query: 537 QPSDQHFTSAVHQKHKDHFRLTIPRKSKLAVHRNIRDDEGFIIRHFAGAVCYETTQFVEK 596
+ +DQ++ ++ +H PR S A FII HFA V Y + F+EK
Sbjct: 518 KGTDQNWAQKLYDRHSSSQHFQKPRMSNTA----------FIIVHFADKVEYLSDGFLEK 567
Query: 597 NNDALHMSLESLICESRDKFIRELFESSTNNNKDTKQKAGKLSFIS-------------- 642
N D ++ +++ S+ + +LF + T G S IS
Sbjct: 568 NRDTVYEEQINILKASKFPLVADLFHDDKDPVPATTPGKGSSSKISVRSARPPMKVSNKE 627
Query: 643 ----VGNKFKTQLNLLLDKLRSTGASFIRCIKPNLKMTSHHFEGAQILSQLQCSGMVSVL 698
VG++F+T L+LL++ L +T ++RCIKPN + HF+ + + QL+ G++ +
Sbjct: 628 HKKTVGHQFRTSLHLLMETLNATTPHYVRCIKPNDEKLPFHFDPKRAVQQLRACGVLETI 687
Query: 699 DLMQGGYPSRASFHELYNMYKKYMPDK-LARLDPRLFCKALFKALGLNENDYKFGLTKVF 757
+ GYPSR ++H+ +N Y+ + + LA D + C+++ + L + + ++FG TK+F
Sbjct: 688 RISAAGYPSRWAYHDFFNRYRVLVKKRELANTDKKAICRSVLENLIKDPDKFQFGRTKIF 747
Query: 758 FRPGKFAEFDQIMKSDPDHLAELV--KRVNHWLTCSRWKKVQWCSLSVIK-----LKNKI 810
FR G+ A ++ +++D A ++ K V WL ++ +++ +L++ + L ++
Sbjct: 748 FRAGQVAYLEK-LRADKFRTATIMIQKTVRGWLQKVKYHRLKGATLTLQRYCRGHLARRL 806
Query: 811 K---YRAEACIKMQKTIRMWLCKRRHKPRIDGLVKVGTLKKRLDKFNEVVSVLKDGKPEM 867
R A + +QK RM ++ ++ V + + + VL + K
Sbjct: 807 AEHLRRIRAAVVLQKHYRMQRARQAYQRVRRAAVVIQAFTRAMFVRRTYRQVLMEHKA-- 864
Query: 868 NKQIKNLEISIDTLMAKIKSTMMTQEQIQKEYDA--LVKSSEELLSALQKKKQ---QEEE 922
T + K M + Q+ DA +++ + +L A ++ K +
Sbjct: 865 ------------TTIQKHVRGWMARRHFQRLRDAAIVIQCAFRMLKARRELKALRIEARS 912
Query: 923 AERLRRIQEEMEKE--RKRREEDEKRRRKEEEERRMKL-----EMEAKRKQEE---EERK 972
AE L+R+ ME + + +R+ DE+ + + ++ + ME +R ++E ++
Sbjct: 913 AEHLKRLNVGMENKVVQLQRKIDEQNKEFKTLSEQLSVTTSTYTMEVERLKKELVHYQQS 972
Query: 973 KREDDEKRIQAEVEAQLARQKEEESQQQAVLEQERRDR-ELALRIAQSEAE--LISDEAQ 1029
ED R+Q EVE+ + S+++ + + R++ EL R+A E E L+ DE +
Sbjct: 973 PGEDTSLRLQEEVESLRTELQRAHSERKILEDAHSREKDELRKRVADLEQENALLKDEKE 1032
Query: 1030 ----ADLALRRNDGTRPKMTPEQMAKEMSEFLSRGPAVLATKAAAGTKKYDLSKWKYAEL 1085
L +++ + + M KE+ E SR ++ K+Y + +Y L
Sbjct: 1033 QLNNQILCQSKDEFAQNSVKENLMKKELEEERSRYQNLV--------KEYSQLEQRYDNL 1084
Query: 1086 RD 1087
RD
Sbjct: 1085 RD 1086
Score = 35.4 bits (80), Expect = 0.35
Identities = 48/229 (20%), Positives = 92/229 (40%), Gaps = 38/229 (16%)
Query: 821 QKTIRMWLCKRR---HKPRIDGLVK-VGTLKKRLDKFNEVVSVLKDGKPEMNKQIKNLEI 876
Q +++ L K+ + R LVK L++R D + ++++K +
Sbjct: 1048 QNSVKENLMKKELEEERSRYQNLVKEYSQLEQRYDNLRDEMTIIKQTPGHRRNPSNQSSL 1107
Query: 877 SIDTLMAKIKSTMMTQEQIQKEYDALVKSSEELLSALQKKKQQEEEAERLRRIQEEMEKE 936
D+ I ++ +I DAL + E L+K +L++ E+E+E
Sbjct: 1108 ESDSNYPSISTS-----EIGDTEDALQQVEE---IGLEKAAMDMTVFLKLQKRVRELEQE 1159
Query: 937 R--------KRREEDEKRRRKEEEERRMKLEMEA-------KRKQEEEERKKREDDEKRI 981
R KR ++D K+ + E + + L+ A KR++ E E KK ++D +
Sbjct: 1160 RKKLQVQLEKREQQDSKKVQAEPPQTDIDLDPNADLAYNSLKRQELESENKKLKNDLNEL 1219
Query: 982 QAEVEAQLARQKEEESQQQA---VLEQERRDRELALRIAQSEAELISDE 1027
+ V Q + + +L Q L++A E E+ +E
Sbjct: 1220 RKAVADQATQNNSSHGSPDSYSLLLNQ--------LKLAHEELEVRKEE 1260
Score = 31.2 bits (69), Expect = 6.7
Identities = 39/169 (23%), Positives = 73/169 (43%), Gaps = 28/169 (16%)
Query: 899 YDALVKSSEELLSALQKKK-QQEEEAERLRR----IQEEMEKERKR-------REEDEKR 946
Y L + + L + LQ + + EEE E L+ ++EEM+K+++ E +
Sbjct: 1333 YQGLKQVARLLEAQLQAQSLEHEEEVEHLKAQLEALKEEMDKQQQTFCQTLLLSPEAQVE 1392
Query: 947 RRKEEEERRMKLE----MEAKRKQEEEERK---------KREDDEKRIQAEVEAQLARQK 993
++E R+ E E K E+ ERK K+ D + QA +++ +K
Sbjct: 1393 FGVQQEISRLTNENLDLKELVEKLEKNERKLKKQLKIYMKKAQDLEAAQALAQSE---RK 1449
Query: 994 EEESQQQAVLEQERRDRELALRIAQSEAELISDEAQADLALRRNDGTRP 1042
E +Q ++++ +D + L + + L+ DL + GT P
Sbjct: 1450 RHELNRQVTVQRKEKDFQGMLEYHKEDEALLIRNLVTDLKPQMLSGTVP 1498
Score = 31.2 bits (69), Expect = 6.7
Identities = 31/150 (20%), Positives = 66/150 (44%), Gaps = 20/150 (13%)
Query: 866 EMNKQIKNLEISIDTLMAKIKSTMMTQEQIQKEYDALVKSSEELLSALQKKKQQEEEAER 925
E +++++L+ ++ L K M Q+Q + L ++ Q+ + E
Sbjct: 1353 EHEEEVEHLKAQLEAL----KEEMDKQQQTFCQTLLLSPEAQVEFGVQQEISRLTNENLD 1408
Query: 926 LRRIQEEMEKERKRREEDEKRRRKEEEERRMKLEMEAKRKQEEEERKKREDDEKRIQAEV 985
L+ + E++EK ++ ++ K K+ ++ +EA + + ERK+ E + +V
Sbjct: 1409 LKELVEKLEKNERKLKKQLKIYMKKAQD------LEAAQALAQSERKRHE-----LNRQV 1457
Query: 986 EAQLARQKEEESQQQAVLEQERRDRELALR 1015
Q +E Q +LE + D L +R
Sbjct: 1458 TVQ-----RKEKDFQGMLEYHKEDEALLIR 1482
>gi|215982794 myosin VA isoform 2 [Homo sapiens]
Length = 1828
Score = 496 bits (1277), Expect = e-140
Identities = 331/1033 (32%), Positives = 555/1033 (53%), Gaps = 123/1033 (11%)
Query: 61 DNCSLMYLNEATLLHNIKVRYSKDR-IYTYVANILIAVNPYFDIPKIYSSEAIKSYQGKS 119
D +L YL+E +LHN++VR+ + IYTY +L+A+NPY +P IY + I +Y G++
Sbjct: 73 DLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLP-IYGEDIINAYSGQN 131
Query: 120 LGTRPPHVFAIADKAFRDMKVLKMSQSIIVSGESGAGKTENTKFVLRYLTESYGTGQD-- 177
+G PH+FA+A++A++ M + +QSIIVSGESGAGKT + K+ +RY G+ +
Sbjct: 132 MGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGSASEAN 191
Query: 178 IDDRIVEANPLLEAFGNAKTVRNNNSSRFGKFVEIHFNEKSSVVGGFVSHYLLEKSRICV 237
++++++ +NP++E+ GNAKT RN+NSSRFGK++EI F+++ ++G + YLLEKSR+
Sbjct: 192 VEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRTYLLEKSRVVF 251
Query: 238 QGKEERNYHIFYRLCAGASEDIREKLHLSSPDNFRYLNRGCTRYFANKETDKQILQNRKS 297
Q +EERNYHIFY+LCA A + L L + DNF Y +G + + K++ R++
Sbjct: 252 QAEEERNYHIFYQLCASAKLPEFKMLRLGNADNFNYTKQGGSPVIEGVDDAKEMAHTRQA 311
Query: 298 PEYLKAGSMKDPLLDDHGDFIRMCTAMKKIGLDDEEKLDLFRVVAGVLHLGNIDFEEAGS 357
CT +G+ + ++ +FR++AG+LHLGN+ F +
Sbjct: 312 -----------------------CTL---LGISESHQMGIFRILAGILHLGNVGFTSRDA 345
Query: 358 TSGGCNLKNKSAQSLEYCAELLGLDQDDLRVSLTTRVMLTTAGGTKGTVIKVPLKVEQAN 417
S C + K +C +L+G+D +++ L R + T T IK P+ QA
Sbjct: 346 DS--CTIPPKHEPLCIFC-DLMGVDYEEMCHWLCHRKLATAT----ETYIK-PISKLQAT 397
Query: 418 NARDALAKTVYSHLFDHVVNRVNQCFPFETSSY-FIGVLDIAGFEYFEHNSFEQFCINYC 476
NARDALAK +Y+ LF+ +V+ VNQ + FIGVLDI GFE FE NSFEQFCINY
Sbjct: 398 NARDALAKHIYAKLFNWIVDNVNQALHSAVKQHSFIGVLDIYGFETFEINSFEQFCINYA 457
Query: 477 NEKLQQFFNERILKEEQELYQKEGLGVNEVHYVDNQDCIDLIEAKLVGILDILDEENRLP 536
NEKLQQ FN + K EQE Y KE + + + DNQ CI+LIE+KL GILD+LDEE ++P
Sbjct: 458 NEKLQQQFNMHVFKLEQEEYMKEQIPWTLIDFYDNQPCINLIESKL-GILDLLDEECKMP 516
Query: 537 QPSDQHFTSAVHQKHKDHFRLTIPRKSKLAVHRNIRDDEGFIIRHFAGAVCYETTQFVEK 596
+ +D + ++ H + + + K +L+ ++ FII+HFA V Y+ F+EK
Sbjct: 517 KGTDDTWAQKLYNTHLN--KCALFEKPRLS-------NKAFIIQHFADKVEYQCEGFLEK 567
Query: 597 NNDALHMSLESLICESRDKFIRELFE---------SSTNNN---------KDTKQKAGKL 638
N D + ++ S+ K + ELF+ S+T++ K TK + G++
Sbjct: 568 NKDTVFEEQIKVLKSSKFKMLPELFQDDEKAISPTSATSSGRTPLTRTPAKPTKGRPGQM 627
Query: 639 S---FISVGNKFKTQLNLLLDKLRSTGASFIRCIKPNLKMTSHHFEGAQILSQLQCSGMV 695
+ +VG++F+ L+LL++ L +T ++RCIKPN F+ + + QL+ G++
Sbjct: 628 AKEHKKTVGHQFRNSLHLLMETLNATTPHYVRCIKPNDFKFPFTFDEKRAVQQLRACGVL 687
Query: 696 SVLDLMQGGYPSRASFHELYNMYKKYMPDKLARLDPRLFCKALFKALGLNENDYKFGLTK 755
+ + G+PSR ++ E ++ Y+ M K D + CK + + L L+++ Y+FG TK
Sbjct: 688 ETIRISAAGFPSRWTYQEFFSRYRVLMKQKDVLSDRKQTCKNVLEKLILDKDKYQFGKTK 747
Query: 756 VFFRPGKFAEFDQIMKSDPDHLA--ELVKRVNHWLTCSRWKKVQWCSLSV--------IK 805
+FFR G+ A ++ +++D A + K + WL ++ +++ ++++ +
Sbjct: 748 IFFRAGQVAYLEK-LRADKLRAACIRIQKTIRGWLLRKKYLRMRKAAITMQRYVRGYQAR 806
Query: 806 LKNKIKYRAEACIKMQKTIRMWLCKRRHKPRIDGLVKVGTLKKRLDKFNEVVSVLKDGKP 865
K R +A +QK RM++ +RR+K R + + + + N +L++ K
Sbjct: 807 CYAKFLRRTKAATIIQKYWRMYVVRRRYKIRRAATIVLQSYLRGFLARNRYRKILREHKA 866
Query: 866 E-MNKQIKN----------------LEISIDTLMAK--IKSTMMTQEQIQKEYDALVKSS 906
+ K+++ L+ +MAK +K + +++ Y L
Sbjct: 867 VIIQKRVRGWLARTHYKRSMHAIIYLQCCFRRMMAKRELKKLKIEARSVER-YKKLHIGM 925
Query: 907 EELLSALQKKKQQEEE-----AERLRRIQEEMEKERKRREEDEKRRRKEEEE------RR 955
E + LQ+K ++ + E+L ++ E ++ D +R + EEE R
Sbjct: 926 ENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNSETEKLRSDLERLQLSEEEAKVATGRV 985
Query: 956 MKLEMEAKR-----KQEEEERKKREDDEKRIQAEVEAQLARQKEEESQQQAVLEQERRDR 1010
+ L+ E + +Q E+K E+ R + E E ++ KEE + +L+QE+
Sbjct: 986 LSLQEEIAKLRKDLEQTRSEKKCIEEHADRYKQETEQLVSNLKEENT----LLKQEK--E 1039
Query: 1011 ELALRIAQSEAEL 1023
L RI Q E+
Sbjct: 1040 ALNHRIVQQAKEM 1052
Score = 40.8 bits (94), Expect = 0.008
Identities = 46/229 (20%), Positives = 104/229 (45%), Gaps = 26/229 (11%)
Query: 775 DHLAELV-KRVNHWLTCSRWKK-------VQWCSLSVIKLKNKIKYRAEACIKMQKTIRM 826
+H A ++ KRV WL + +K+ +Q C ++ + K + EA +++
Sbjct: 863 EHKAVIIQKRVRGWLARTHYKRSMHAIIYLQCCFRRMMAKRELKKLKIEA-----RSV-- 915
Query: 827 WLCKRRHKPRIDGLVKVGTLKKRLDKFNE----VVSVLKDGKPEMNKQIKNLEISIDTLM 882
+R K I K+ L++++D+ N+ +V L + + N + + L ++ L
Sbjct: 916 ---ERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNSETEKLRSDLERLQ 972
Query: 883 AKIKSTMMTQEQIQKEYDALVKSSEELLSALQKKKQQEEEAERLRRIQEEMEKERKRREE 942
+ + ++ + + K ++L +KK EE A+R ++ E++ K E
Sbjct: 973 LSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIEEHADRYKQETEQLVSNLK---E 1029
Query: 943 DEKRRRKEEEERRMKLEMEAKRKQEEEERKKREDDEKRIQAEVEAQLAR 991
+ ++E+E ++ +AK E E KK ++ K+++ ++ + R
Sbjct: 1030 ENTLLKQEKEALNHRIVQQAKEMTETME-KKLVEETKQLELDLNDERLR 1077
Score = 34.7 bits (78), Expect = 0.60
Identities = 41/203 (20%), Positives = 86/203 (42%), Gaps = 31/203 (15%)
Query: 846 LKKRLDKFNEVVS------VLKDGKPEMNKQIKNLEISIDTLMAKIKSTMMTQEQIQKEY 899
LK L++ + +S V G P ++ L + L + + ++ + Q+ +
Sbjct: 1218 LKNELNELRKALSEKSAPEVTAPGAPAYRVLMEQLTSVSEELDVRKEEVLILRSQLVSQK 1277
Query: 900 DALVKSSEE--------LLSALQKKKQQEEEAE------RLRRIQEEMEKERKRREEDEK 945
+A+ ++ LL +QK K + E A+ R+ E + +KR E+E
Sbjct: 1278 EAIQPKDDKNTMTDSTILLEDVQKMKDKGEIAQAYIGLKETNRLLESQLQSQKRSHENEA 1337
Query: 946 RRRKEEEERRMKLEMEAKRKQEEEERKKREDDEKRIQAEVEAQLARQKEE--------ES 997
+ E + L+ E R+Q+ + + E RI+A ++ ++ R E E
Sbjct: 1338 EALRGEIQ---SLKEENNRQQQLLAQNLQLPPEARIEASLQHEITRLTNENLDLMEQLEK 1394
Query: 998 QQQAVLEQERRDRELALRIAQSE 1020
Q + V + +++ + A +I + E
Sbjct: 1395 QDKTVRKLKKQLKVFAKKIGELE 1417
Score = 33.1 bits (74), Expect = 1.8
Identities = 27/92 (29%), Positives = 46/92 (50%), Gaps = 14/92 (15%)
Query: 891 TQEQIQKEYDALVKSSEELLSALQKKKQQEEEAERLRRIQEEMEKERKRREEDEKRRRKE 950
T+E +K+ V L LQK+ + E+ +++ M+ E R+EE R + +
Sbjct: 1140 TEEPSEKK----VPLDMSLFLKLQKRVTELEQEKQV------MQDELDRKEEQVLRSKAK 1189
Query: 951 EEERRM----KLEMEAKRKQEEEERKKREDDE 978
EEER +LE E+ ++QE E K+ +E
Sbjct: 1190 EEERPQIRGAELEYESLKRQELESENKKLKNE 1221
Score = 32.7 bits (73), Expect = 2.3
Identities = 41/200 (20%), Positives = 84/200 (42%), Gaps = 35/200 (17%)
Query: 846 LKKRLDKFNE-VVSVLKDGKPEMNKQI----KNLEISIDTLMAKIKSTMMTQEQIQKEYD 900
LK+ + N +V K+ M K++ K LE+ ++ + ++ + ++++ YD
Sbjct: 1034 LKQEKEALNHRIVQQAKEMTETMEKKLVEETKQLELDLNDERLRYQNLLNEFSRLEERYD 1093
Query: 901 ALVKSSEELLSALQKKKQQEEEAERLRRIQE----------EMEKERKRREEDEKRR--- 947
L EE+ + K + + E EME R EE +++
Sbjct: 1094 DL---KEEMTLMVHVPKPGHKRTDSTHSSNESEYIFSSEIAEMEDIPSRTEEPSEKKVPL 1150
Query: 948 -------------RKEEEERRMKLEMEAKRKQEEEERKKREDDEKRIQAEVEAQLARQKE 994
E+E++ M+ E++ K +Q + K E+ + AE+E + +++E
Sbjct: 1151 DMSLFLKLQKRVTELEQEKQVMQDELDRKEEQVLRSKAKEEERPQIRGAELEYESLKRQE 1210
Query: 995 EESQQQAVLEQERRDRELAL 1014
ES+ + L+ E + AL
Sbjct: 1211 LESENKK-LKNELNELRKAL 1229
>gi|215982791 myosin VA isoform 1 [Homo sapiens]
Length = 1855
Score = 496 bits (1277), Expect = e-140
Identities = 331/1033 (32%), Positives = 555/1033 (53%), Gaps = 123/1033 (11%)
Query: 61 DNCSLMYLNEATLLHNIKVRYSKDR-IYTYVANILIAVNPYFDIPKIYSSEAIKSYQGKS 119
D +L YL+E +LHN++VR+ + IYTY +L+A+NPY +P IY + I +Y G++
Sbjct: 73 DLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLP-IYGEDIINAYSGQN 131
Query: 120 LGTRPPHVFAIADKAFRDMKVLKMSQSIIVSGESGAGKTENTKFVLRYLTESYGTGQD-- 177
+G PH+FA+A++A++ M + +QSIIVSGESGAGKT + K+ +RY G+ +
Sbjct: 132 MGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGSASEAN 191
Query: 178 IDDRIVEANPLLEAFGNAKTVRNNNSSRFGKFVEIHFNEKSSVVGGFVSHYLLEKSRICV 237
++++++ +NP++E+ GNAKT RN+NSSRFGK++EI F+++ ++G + YLLEKSR+
Sbjct: 192 VEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRTYLLEKSRVVF 251
Query: 238 QGKEERNYHIFYRLCAGASEDIREKLHLSSPDNFRYLNRGCTRYFANKETDKQILQNRKS 297
Q +EERNYHIFY+LCA A + L L + DNF Y +G + + K++ R++
Sbjct: 252 QAEEERNYHIFYQLCASAKLPEFKMLRLGNADNFNYTKQGGSPVIEGVDDAKEMAHTRQA 311
Query: 298 PEYLKAGSMKDPLLDDHGDFIRMCTAMKKIGLDDEEKLDLFRVVAGVLHLGNIDFEEAGS 357
CT +G+ + ++ +FR++AG+LHLGN+ F +
Sbjct: 312 -----------------------CTL---LGISESHQMGIFRILAGILHLGNVGFTSRDA 345
Query: 358 TSGGCNLKNKSAQSLEYCAELLGLDQDDLRVSLTTRVMLTTAGGTKGTVIKVPLKVEQAN 417
S C + K +C +L+G+D +++ L R + T T IK P+ QA
Sbjct: 346 DS--CTIPPKHEPLCIFC-DLMGVDYEEMCHWLCHRKLATAT----ETYIK-PISKLQAT 397
Query: 418 NARDALAKTVYSHLFDHVVNRVNQCFPFETSSY-FIGVLDIAGFEYFEHNSFEQFCINYC 476
NARDALAK +Y+ LF+ +V+ VNQ + FIGVLDI GFE FE NSFEQFCINY
Sbjct: 398 NARDALAKHIYAKLFNWIVDNVNQALHSAVKQHSFIGVLDIYGFETFEINSFEQFCINYA 457
Query: 477 NEKLQQFFNERILKEEQELYQKEGLGVNEVHYVDNQDCIDLIEAKLVGILDILDEENRLP 536
NEKLQQ FN + K EQE Y KE + + + DNQ CI+LIE+KL GILD+LDEE ++P
Sbjct: 458 NEKLQQQFNMHVFKLEQEEYMKEQIPWTLIDFYDNQPCINLIESKL-GILDLLDEECKMP 516
Query: 537 QPSDQHFTSAVHQKHKDHFRLTIPRKSKLAVHRNIRDDEGFIIRHFAGAVCYETTQFVEK 596
+ +D + ++ H + + + K +L+ ++ FII+HFA V Y+ F+EK
Sbjct: 517 KGTDDTWAQKLYNTHLN--KCALFEKPRLS-------NKAFIIQHFADKVEYQCEGFLEK 567
Query: 597 NNDALHMSLESLICESRDKFIRELFE---------SSTNNN---------KDTKQKAGKL 638
N D + ++ S+ K + ELF+ S+T++ K TK + G++
Sbjct: 568 NKDTVFEEQIKVLKSSKFKMLPELFQDDEKAISPTSATSSGRTPLTRTPAKPTKGRPGQM 627
Query: 639 S---FISVGNKFKTQLNLLLDKLRSTGASFIRCIKPNLKMTSHHFEGAQILSQLQCSGMV 695
+ +VG++F+ L+LL++ L +T ++RCIKPN F+ + + QL+ G++
Sbjct: 628 AKEHKKTVGHQFRNSLHLLMETLNATTPHYVRCIKPNDFKFPFTFDEKRAVQQLRACGVL 687
Query: 696 SVLDLMQGGYPSRASFHELYNMYKKYMPDKLARLDPRLFCKALFKALGLNENDYKFGLTK 755
+ + G+PSR ++ E ++ Y+ M K D + CK + + L L+++ Y+FG TK
Sbjct: 688 ETIRISAAGFPSRWTYQEFFSRYRVLMKQKDVLSDRKQTCKNVLEKLILDKDKYQFGKTK 747
Query: 756 VFFRPGKFAEFDQIMKSDPDHLA--ELVKRVNHWLTCSRWKKVQWCSLSV--------IK 805
+FFR G+ A ++ +++D A + K + WL ++ +++ ++++ +
Sbjct: 748 IFFRAGQVAYLEK-LRADKLRAACIRIQKTIRGWLLRKKYLRMRKAAITMQRYVRGYQAR 806
Query: 806 LKNKIKYRAEACIKMQKTIRMWLCKRRHKPRIDGLVKVGTLKKRLDKFNEVVSVLKDGKP 865
K R +A +QK RM++ +RR+K R + + + + N +L++ K
Sbjct: 807 CYAKFLRRTKAATIIQKYWRMYVVRRRYKIRRAATIVLQSYLRGFLARNRYRKILREHKA 866
Query: 866 E-MNKQIKN----------------LEISIDTLMAK--IKSTMMTQEQIQKEYDALVKSS 906
+ K+++ L+ +MAK +K + +++ Y L
Sbjct: 867 VIIQKRVRGWLARTHYKRSMHAIIYLQCCFRRMMAKRELKKLKIEARSVER-YKKLHIGM 925
Query: 907 EELLSALQKKKQQEEE-----AERLRRIQEEMEKERKRREEDEKRRRKEEEE------RR 955
E + LQ+K ++ + E+L ++ E ++ D +R + EEE R
Sbjct: 926 ENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNSETEKLRSDLERLQLSEEEAKVATGRV 985
Query: 956 MKLEMEAKR-----KQEEEERKKREDDEKRIQAEVEAQLARQKEEESQQQAVLEQERRDR 1010
+ L+ E + +Q E+K E+ R + E E ++ KEE + +L+QE+
Sbjct: 986 LSLQEEIAKLRKDLEQTRSEKKCIEEHADRYKQETEQLVSNLKEENT----LLKQEK--E 1039
Query: 1011 ELALRIAQSEAEL 1023
L RI Q E+
Sbjct: 1040 ALNHRIVQQAKEM 1052
Score = 40.8 bits (94), Expect = 0.008
Identities = 46/229 (20%), Positives = 104/229 (45%), Gaps = 26/229 (11%)
Query: 775 DHLAELV-KRVNHWLTCSRWKK-------VQWCSLSVIKLKNKIKYRAEACIKMQKTIRM 826
+H A ++ KRV WL + +K+ +Q C ++ + K + EA +++
Sbjct: 863 EHKAVIIQKRVRGWLARTHYKRSMHAIIYLQCCFRRMMAKRELKKLKIEA-----RSV-- 915
Query: 827 WLCKRRHKPRIDGLVKVGTLKKRLDKFNE----VVSVLKDGKPEMNKQIKNLEISIDTLM 882
+R K I K+ L++++D+ N+ +V L + + N + + L ++ L
Sbjct: 916 ---ERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNSETEKLRSDLERLQ 972
Query: 883 AKIKSTMMTQEQIQKEYDALVKSSEELLSALQKKKQQEEEAERLRRIQEEMEKERKRREE 942
+ + ++ + + K ++L +KK EE A+R ++ E++ K E
Sbjct: 973 LSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIEEHADRYKQETEQLVSNLK---E 1029
Query: 943 DEKRRRKEEEERRMKLEMEAKRKQEEEERKKREDDEKRIQAEVEAQLAR 991
+ ++E+E ++ +AK E E KK ++ K+++ ++ + R
Sbjct: 1030 ENTLLKQEKEALNHRIVQQAKEMTETME-KKLVEETKQLELDLNDERLR 1077
Score = 33.1 bits (74), Expect = 1.8
Identities = 27/92 (29%), Positives = 46/92 (50%), Gaps = 14/92 (15%)
Query: 891 TQEQIQKEYDALVKSSEELLSALQKKKQQEEEAERLRRIQEEMEKERKRREEDEKRRRKE 950
T+E +K+ V L LQK+ + E+ +++ M+ E R+EE R + +
Sbjct: 1140 TEEPSEKK----VPLDMSLFLKLQKRVTELEQEKQV------MQDELDRKEEQVLRSKAK 1189
Query: 951 EEERRM----KLEMEAKRKQEEEERKKREDDE 978
EEER +LE E+ ++QE E K+ +E
Sbjct: 1190 EEERPQIRGAELEYESLKRQELESENKKLKNE 1221
Score = 32.7 bits (73), Expect = 2.3
Identities = 41/200 (20%), Positives = 84/200 (42%), Gaps = 35/200 (17%)
Query: 846 LKKRLDKFNE-VVSVLKDGKPEMNKQI----KNLEISIDTLMAKIKSTMMTQEQIQKEYD 900
LK+ + N +V K+ M K++ K LE+ ++ + ++ + ++++ YD
Sbjct: 1034 LKQEKEALNHRIVQQAKEMTETMEKKLVEETKQLELDLNDERLRYQNLLNEFSRLEERYD 1093
Query: 901 ALVKSSEELLSALQKKKQQEEEAERLRRIQE----------EMEKERKRREEDEKRR--- 947
L EE+ + K + + E EME R EE +++
Sbjct: 1094 DL---KEEMTLMVHVPKPGHKRTDSTHSSNESEYIFSSEIAEMEDIPSRTEEPSEKKVPL 1150
Query: 948 -------------RKEEEERRMKLEMEAKRKQEEEERKKREDDEKRIQAEVEAQLARQKE 994
E+E++ M+ E++ K +Q + K E+ + AE+E + +++E
Sbjct: 1151 DMSLFLKLQKRVTELEQEKQVMQDELDRKEEQVLRSKAKEEERPQIRGAELEYESLKRQE 1210
Query: 995 EESQQQAVLEQERRDRELAL 1014
ES+ + L+ E + AL
Sbjct: 1211 LESENKK-LKNELNELRKAL 1229
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 494 bits (1271), Expect = e-139
Identities = 378/1196 (31%), Positives = 599/1196 (50%), Gaps = 154/1196 (12%)
Query: 5 KPVWAPHPTDGFQMGNIVDIGPDSLTIEPLNQKGKTFLALINQVFPAEEDSKKDVEDNCS 64
K VW P GF+ ++ + + +E L + GK + + VED
Sbjct: 30 KLVWVPSDKSGFEPASLKEEVGEEAIVE-LVENGKKVKVNKDDIQKMNPPKFSKVEDMAE 88
Query: 65 LMYLNEATLLHNIKVRYSKDRIYTYVANILIAVNPYFDIPKIYSSEAIKSYQGKSLGTRP 124
L LNEA++LHN+K RY IYTY + +NPY ++P IYS E ++ Y+GK P
Sbjct: 89 LTCLNEASVLHNLKERYYSGLIYTYSGLFCVVINPYKNLP-IYSEEIVEMYKGKKRHEMP 147
Query: 125 PHVFAIADKAFRDMKVLKMSQSIIVSGESGAGKTENTKFVLRYLT---ESYGTGQD---I 178
PH++AI D A+R M + QSI+ +GESGAGKTENTK V++YL S+ + +D +
Sbjct: 148 PHIYAITDTAYRSMMQDREDQSILCTGESGAGKTENTKKVIQYLAYVASSHKSKKDQGEL 207
Query: 179 DDRIVEANPLLEAFGNAKTVRNNNSSRFGKFVEIHFNEKSSVVGGFVSHYLLEKSRICVQ 238
+ ++++ANP+LEAFGNAKTV+N+NSSRFGKF+ I+F+ +VG + YLLEKSR Q
Sbjct: 208 ERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVNGYIVGANIETYLLEKSRAIRQ 267
Query: 239 GKEERNYHIFYRLCAGASEDIREKLHLSSPDNFRYLNRGCTRYFANKETDKQILQNRKSP 298
KEER +HIFY L +GA E ++ L L + +R+L+
Sbjct: 268 AKEERTFHIFYYLLSGAGEHLKTDLLLEPYNKYRFLSN---------------------- 305
Query: 299 EYLKAGSMKDPLLDDHGDFIRMCTAMKKIGLDDEEKLDLFRVVAGVLHLGNIDFEEAGST 358
G + P D F AM+ +G+ +EE++ L RV++GVL LGNI F++ +T
Sbjct: 306 -----GHVTIPGQQDKDMFQETMEAMRIMGIPEEEQMGLLRVISGVLQLGNIVFKKERNT 360
Query: 359 SGGCNLKNKSAQSLEYCAELLGLDQDDLRVSLTTRVMLTTAGGTKGTVIKVPLKVEQANN 418
N +AQ + + LLG++ D TR +LT ++ EQA+
Sbjct: 361 DQASMPDNTAAQKVSH---LLGINVTDF-----TRGILTPRIKVGRDYVQKAQTKEQADF 412
Query: 419 ARDALAKTVYSHLFDHVVNRVNQCF--PFETSSYFIGVLDIAGFEYFEHNSFEQFCINYC 476
A +ALAK Y +F +V R+N+ + FIG+LDIAGFE F+ NSFEQ CINY
Sbjct: 413 AIEALAKATYERMFRWLVLRINKALDKTKRQGASFIGILDIAGFEIFDLNSFEQLCINYT 472
Query: 477 NEKLQQFFNERILKEEQELYQKEGLGVNEVHY-VDNQDCIDLIE--AKLVGILDILDEEN 533
NEKLQQ FN + EQE YQ+EG+ N + + +D Q CIDLIE A GIL +LDEE
Sbjct: 473 NEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIDLIEKPAGPPGILALLDEEC 532
Query: 534 RLPQPSDQHFTSAVHQKHKDHFRLTIPRKSKLAVHRNIRDDEGFIIRHFAGAVCYETTQF 593
P+ +D+ F V Q+ H + P++ ++D F I H+AG V Y+ ++
Sbjct: 533 WFPKATDKSFVEKVMQEQGTHPKFQKPKQ--------LKDKADFCIIHYAGKVDYKADEW 584
Query: 594 VEKNNDALHMSLESLICESRDKFIRELFE------------SSTNNNKDTKQKAGKLSFI 641
+ KN D L+ ++ +L+ +S DKF+ EL++ + K K F
Sbjct: 585 LMKNMDPLNDNIATLLHQSSDKFVSELWKDVDRIIGLDQVAGMSETALPGAFKTRKGMFR 644
Query: 642 SVGNKFKTQLNLLLDKLRSTGASFIRCIKPNLKMTSHHFEGAQILSQLQCSGMVSVLDLM 701
+VG +K QL L+ LR+T +F+RCI PN + + + +L QL+C+G++ + +
Sbjct: 645 TVGQLYKEQLAKLMATLRNTNPNFVRCIIPNHEKKAGKLDPHLVLDQLRCNGVLEGIRIC 704
Query: 702 QGGYPSRASFHELYNMYKKYMPDKLAR--LDPRLFCKALFKALGLNENDYKFGLTKVFFR 759
+ G+P+R F E Y+ P+ + + +D + C + KAL L+ N Y+ G +KVFFR
Sbjct: 705 RQGFPNRVVFQEFRQRYEILTPNSIPKGFMDGKQACVLMIKALELDSNLYRIGQSKVFFR 764
Query: 760 PGKFAEFDQIMKSDPDHLAELVKRVNHWLTCSRWKKVQWCSLSVIKLKNKIKYRAEACIK 819
G A ++ + ++ + + C R + + +K C
Sbjct: 765 AGVLAHLEE------ERDLKITDVIIGFQACCRGYLARKAFAKRQQQLTAMKVLQRNCAA 818
Query: 820 MQKTIRMWLCKRRHKPRIDGLVKVGTLKKRLDKFNEVVSVLKDGKPEMNKQIKNLEISID 879
K +R W R ++ L++V ++ + E + +++ + ++ +E
Sbjct: 819 YLK-LRNWQWWRLF-TKVKPLLQVSRQEEEMMAKEEELVKVREKQLAAENRLTEMETLQS 876
Query: 880 TLMAKIKSTMMTQEQIQKEYDALVKSSEELLSALQKKKQQ------------EEEAERLR 927
LMA+ + QEQ+Q E + L +EEL + L KKQ+ EEE ER +
Sbjct: 877 QLMAE---KLQLQEQLQAETE-LCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQ 932
Query: 928 RIQEEMEKERKRREEDEKRRRKEEEERRMKLEM-----EAKRKQEEEERKKREDD----- 977
+Q E +K ++ +E E+ + +EEE R KL++ EAK K+ EEE+ ED
Sbjct: 933 HLQAEKKKMQQNIQELEE-QLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLA 991
Query: 978 -EKRIQ----AEVEAQLARQKEE------------------------ESQQQAVLEQERR 1008
EK++ AE L ++E+ E +Q+ LE+ RR
Sbjct: 992 KEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRR 1051
Query: 1009 DRE-----LALRIAQSEAELI---------SDEAQADLALRRNDGTRPKMTPE---QMAK 1051
E L+ +IA+ +A++ +E QA LA + + M + ++
Sbjct: 1052 KLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELES 1111
Query: 1052 EMSEFLSRGPAVLATKAAAGTKKYDLSKWKYA---ELRDTINTSCDIELLAACREE 1104
++SE + A++ A +K DL + A EL DT++++ + L + RE+
Sbjct: 1112 QISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQ 1167
Score = 58.5 bits (140), Expect = 4e-08
Identities = 66/301 (21%), Positives = 134/301 (44%), Gaps = 33/301 (10%)
Query: 864 KPEMNKQIKNLEISIDTLMAKIKSTMMTQEQIQKEYDALVKSSEEL---LSALQKKKQQE 920
K E+ + K ++ LM+ + +++K AL + EE+ L L+ + Q
Sbjct: 1492 KAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQAT 1551
Query: 921 EEAE-----RLRRIQEEMEKERKRREE--DEKRRRKEEEERRMKLEMEAKRKQEE---EE 970
E+A+ L+ ++ + E++ + R+E +EK+++ + R M+ E+E +RKQ
Sbjct: 1552 EDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAA 1611
Query: 971 RKKREDDEKRIQAEVEAQLARQKEEESQQQAVLEQERRD------------RELALRIAQ 1018
RKK E D K ++A +++ + ++E +Q L+ + +D E+ + +
Sbjct: 1612 RKKLEMDLKDLEAHIDS-ANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKE 1670
Query: 1019 SEAELISDEA-----QADLALRRNDGTRPKMTPEQMAKEMSEFLSRGPAVLATKAAAGTK 1073
+E +L S EA Q +LA + + +++A E++ +G L K +
Sbjct: 1671 NEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEAR 1730
Query: 1074 KYDLSKWKYAELRDT--INTSCDIELLAACREEFHRRLKVYHAWKSKNKKRNTETEQRAP 1131
L + E +T IN L + L+ HA K++N ++ E + +
Sbjct: 1731 IAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKEL 1790
Query: 1132 K 1132
K
Sbjct: 1791 K 1791
Score = 53.1 bits (126), Expect = 2e-06
Identities = 66/284 (23%), Positives = 128/284 (45%), Gaps = 45/284 (15%)
Query: 794 KKVQWCSLSVIKLKNKIKYRAEACIKMQKTIRMWLCK------RRHKPRIDGLVKVGTLK 847
K++ V +K K++ + C++ + ++ L K +RH+ ++ K+ K
Sbjct: 1357 KQIATLHAQVADMKKKME-DSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTK 1415
Query: 848 KRLDKFNEVVSVLKDGKPEMNKQIKNLEISIDTLMAKIK--STMMTQEQIQKEYDALVKS 905
RL + + + V D + + ++ + D L+A+ K S +E+ + E +A K
Sbjct: 1416 TRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKE 1475
Query: 906 SE--ELLSALQKKKQQEEEAERLRR------------------IQEEMEKERKRREE--D 943
++ L AL++ +Q+ E ERL + E+EK ++ E+ +
Sbjct: 1476 TKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVE 1535
Query: 944 EKRRRKEE--------EERRMKLEMEAKRKQEEEERKKREDDEKRIQAEVEAQLARQKEE 995
E + + EE E+ +++LE+ + + + ER + DE+ E + QL RQ E
Sbjct: 1536 EMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQ--SEEKKKQLVRQVRE 1593
Query: 996 ESQQQAVLEQERRDRELALRIAQS-EAELISDEAQADLALRRND 1038
+A LE ER+ R +A+ + E +L EA D A + D
Sbjct: 1594 ---MEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRD 1634
Score = 51.2 bits (121), Expect = 6e-06
Identities = 73/334 (21%), Positives = 141/334 (42%), Gaps = 70/334 (20%)
Query: 852 KFNEVVSVLKDGKPEMNKQIKNLEISIDTLMAKI-----KSTMMTQE------QIQKEYD 900
KFNE V + E+ ++ L++ +D + + KS+ +T++ Q+Q +
Sbjct: 1260 KFNEGERV----RTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQE 1315
Query: 901 ALVKSSEELLSALQKKKQQEEEAERLRRIQEEMEKERKRREE----------DEKRRRK- 949
L + + + LS K KQ E+E R EE E+ + E+ D K++ +
Sbjct: 1316 LLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMED 1375
Query: 950 --------EEEERRMKLEMEAKRKQEEEE---RKKREDDEKRIQAEVEAQLA-------- 990
EE +R+++ ++E ++ EE+ K E + R+Q E++ L
Sbjct: 1376 SVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQS 1435
Query: 991 ---RQKEEESQQQAVLEQERRDRELALRIAQSEAELISDEAQA-DLALRRNDGTRPKMTP 1046
+K+++ Q + E++ + A ++EAE E +A LA + K
Sbjct: 1436 ACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAEL 1495
Query: 1047 EQMAKEMSEFLSRGPAVLATKAAAGTKKYDLSKWKYA-------------ELRDTINTSC 1093
E++ K +F + ++++K G ++L K K A EL D + +
Sbjct: 1496 ERLNK---QFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATE 1552
Query: 1094 DIEL-----LAACREEFHRRLKVYHAWKSKNKKR 1122
D +L L A + +F R L+ + KK+
Sbjct: 1553 DAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQ 1586
Score = 48.9 bits (115), Expect = 3e-05
Identities = 48/236 (20%), Positives = 108/236 (45%), Gaps = 34/236 (14%)
Query: 828 LCKRRHKPRIDGLVKVGTLKKRLDKFNEVVSVLKDGKPEMNKQIKNLEISIDTLMAKIKS 887
L + ++ ++ K+ ++ + F E + ++ K + KQI L + + K++
Sbjct: 1316 LLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMED 1375
Query: 888 TM-------MTQEQIQKEYDALVKSSEELLSALQK----KKQQEEEAERL-------RRI 929
++ + ++QK+ + L + EE ++A K K + ++E + L R+
Sbjct: 1376 SVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQS 1435
Query: 930 QEEMEKERKRREE---DEKRRRKEEEERRMKLEMEAKRKQEE------------EERKKR 974
+EK++K+ ++ +EK + E R + E EA+ K+ + E++ +
Sbjct: 1436 ACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAEL 1495
Query: 975 EDDEKRIQAEVEAQLARQKEEESQQQAVLEQERRDRELALRIAQSEAELISDEAQA 1030
E K+ + E+E L K++ + LE+ +R E + +++ E + DE QA
Sbjct: 1496 ERLNKQFRTEME-DLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQA 1550
Score = 45.1 bits (105), Expect = 4e-04
Identities = 75/354 (21%), Positives = 147/354 (41%), Gaps = 49/354 (13%)
Query: 800 SLSVIKLKNKIKYRA---EACIKMQKTIRMWLCKRRHKPRIDGL----------VKVGTL 846
S S+ KLKNK + E ++ ++ R L K R K D ++ L
Sbjct: 1015 SKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAEL 1074
Query: 847 KKRLDKFNEVVSV----LKDGKPEMN---KQIKNLEISIDTLMAKIKSTMMTQEQIQKEY 899
K +L K E + +++ + N K+I+ LE I L ++S ++ + +K+
Sbjct: 1075 KMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQ- 1133
Query: 900 DALVKSSEELLSALQKKKQQEEEAERLRRIQEEMEKERKRREEDEKRRRKEEEE--RRMK 957
+L L+ K + E+ Q+E+ +R++ K+ +EE +
Sbjct: 1134 ------KRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQI 1187
Query: 958 LEMEAKRKQEEEERKKREDDEKRIQAEVE---AQLARQKEEESQQQAVLEQERRDRELAL 1014
EM K Q EE ++ + KR++A +E L ++ E + + VL Q + D E
Sbjct: 1188 QEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKR 1247
Query: 1015 RIAQSEAELISDEAQADLALRRNDGTRPKMTPEQMAKEMSEFLSRGPAVLATKAAAGTKK 1074
+ +++ + +L ++ N+G R + ++ L +L+ + +K
Sbjct: 1248 KKVEAQLQ--------ELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKL 1299
Query: 1075 YDLSKWKYAELRDTINTSCDIELLAACREEFHRRLKVYHAWKSKNKKRNTETEQ 1128
++L+DT ELL +EE ++L + K ++N+ EQ
Sbjct: 1300 TKDFSALESQLQDT------QELL---QEENRQKLSLSTKLKQVEDEKNSFREQ 1344
Score = 42.0 bits (97), Expect = 0.004
Identities = 41/223 (18%), Positives = 96/223 (43%), Gaps = 27/223 (12%)
Query: 842 KVGTLKKRLDKFNEVVSVLKDGKPEMNKQIKNLEISIDTLMAKIKSTMMTQEQIQKEYDA 901
++ L++ L++ ++ D + N QI + ++ + + ++Q++++
Sbjct: 1730 RIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKE 1789
Query: 902 LVKSSEELLSALQKKKQQEEEA--ERLRRIQEEMEKERKRREEDEKRRRKEEEERRMKLE 959
L +E+ ++ K + A ++ +++E+++ E K R+ K+ R+ E++ + L
Sbjct: 1790 LKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVL- 1848
Query: 960 MEAKRKQEEEERKKREDDEKRIQAEVE----------AQLARQKEEESQQQAVLEQERRD 1009
+ DDE+R + + QL RQ EE ++ RR
Sbjct: 1849 -------------LQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRK 1895
Query: 1010 RELALRIAQSEAELISDEAQADLALRRNDGTRPKMTPEQMAKE 1052
+ L A A+ ++ E + L + G P + P +MA++
Sbjct: 1896 LQRELEDATETADAMNREV-SSLKNKLRRGDLPFVVPRRMARK 1937
Score = 33.9 bits (76), Expect = 1.0
Identities = 29/130 (22%), Positives = 59/130 (45%), Gaps = 11/130 (8%)
Query: 830 KRRHKPRIDGL-VKVGTLKKRLDKFNEVVSVLKDGKPEMNKQIKNLEISIDTLMAKIKST 888
K ++K I L K+ L+++LD NE + KQ++ E + ++ ++
Sbjct: 1802 KSKYKASITALEAKIAQLEEQLD--NETKE-----RQAACKQVRRTEKKLKDVLLQVDDE 1854
Query: 889 MMTQEQIQKEYDALVKSSEELLSALQKKKQQEEEAERLRRIQEEMEKERKRREEDEKRRR 948
EQ + + D K+S L ++ ++ EEEA+R + ++++E + E
Sbjct: 1855 RRNAEQYKDQAD---KASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADAMN 1911
Query: 949 KEEEERRMKL 958
+E + KL
Sbjct: 1912 REVSSLKNKL 1921
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 490 bits (1261), Expect = e-138
Identities = 381/1218 (31%), Positives = 608/1218 (49%), Gaps = 165/1218 (13%)
Query: 5 KPVWAPHPTDGFQMGNIVDIGPDSLTIEPLNQKGKTFLALINQVFPAEEDSKKDVEDNCS 64
K VW P GF+ +I + D + +E L + GK + + + VED
Sbjct: 34 KLVWIPSERHGFEAASIKEERGDEVMVE-LAENGKKAMVNKDDIQKMNPPKFSKVEDMAE 92
Query: 65 LMYLNEATLLHNIKVRYSKDRIYTYVANILIAVNPYFDIPKIYSSEAIKSYQGKSLGTRP 124
L LNEA++LHN+K RY IYTY + +NPY ++P IYS I+ Y+GK P
Sbjct: 93 LTCLNEASVLHNLKDRYYSGLIYTYSGLFCVVINPYKNLP-IYSENIIEMYRGKKRHEMP 151
Query: 125 PHVFAIADKAFRDMKVLKMSQSIIVSGESGAGKTENTKFVLRYLT---------ESYGTG 175
PH++AI++ A+R M + QSI+ +GESGAGKTENTK V++YL + +
Sbjct: 152 PHIYAISESAYRCMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSHKGRKDHNIP 211
Query: 176 QDIDDRIVEANPLLEAFGNAKTVRNNNSSRFGKFVEIHFNEKSSVVGGFVSHYLLEKSRI 235
+++ ++++ANP+LE+FGNAKTV+N+NSSRFGKF+ I+F+ +VG + YLLEKSR
Sbjct: 212 GELERQLLQANPILESFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRA 271
Query: 236 CVQGKEERNYHIFYRLCAGASEDIREKLHLSSPDNFRYLNRGCTRYFANKETDKQILQNR 295
Q K+ER +HIFY+L +GA E ++ L L +N+R+L+ G
Sbjct: 272 VRQAKDERTFHIFYQLLSGAGEHLKSDLLLEGFNNYRFLSNG------------------ 313
Query: 296 KSPEYLKAGSMKDPLLDDHGDFIRMCTAMKKIGLDDEEKLDLFRVVAGVLHLGNIDFEEA 355
Y+ P D +F AM +G EE L + +VV+ VL GNI F++
Sbjct: 314 ----YIPI-----PGQQDKDNFQETMEAMHIMGFSHEEILSMLKVVSSVLQFGNISFKKE 364
Query: 356 GSTSGGCNLKNKSAQSLEYCAELLGLDQDDLRVSLTTRVMLTTAGGTKGTVIKVPLKVEQ 415
+T +N AQ L LLG++ V TR +LT ++ EQ
Sbjct: 365 RNTDQASMPENTVAQKL---CHLLGMN-----VMEFTRAILTPRIKVGRDYVQKAQTKEQ 416
Query: 416 ANNARDALAKTVYSHLFDHVVNRVNQCFPF--ETSSYFIGVLDIAGFEYFEHNSFEQFCI 473
A+ A +ALAK Y LF +V+R+N+ + FIG+LDIAGFE FE NSFEQ CI
Sbjct: 417 ADFAVEALAKATYERLFRWLVHRINKALDRTKRQGASFIGILDIAGFEIFELNSFEQLCI 476
Query: 474 NYCNEKLQQFFNERILKEEQELYQKEGLGVNEVHY-VDNQDCIDLIE--AKLVGILDILD 530
NY NEKLQQ FN + EQE YQ+EG+ N + + +D Q CIDLIE A G+L +LD
Sbjct: 477 NYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIDLIERPANPPGVLALLD 536
Query: 531 EENRLPQPSDQHFTSAVHQKHKDHFRLTIPRKSKLAVHRNIRDDEGFIIRHFAGAVCYET 590
EE P+ +D+ F + Q+ H SK R ++D F I H+AG V Y+
Sbjct: 537 EECWFPKATDKTFVEKLVQEQGSH--------SKFQKPRQLKDKADFCIIHYAGKVDYKA 588
Query: 591 TQFVEKNNDALHMSLESLICESRDKFIRELFE------------SSTNNNKDTKQKAGKL 638
+++ KN D L+ ++ +L+ +S D+F+ EL++ T + K K
Sbjct: 589 DEWLMKNMDPLNDNVATLLHQSSDRFVAELWKDVDRIVGLDQVTGMTETAFGSAYKTKKG 648
Query: 639 SFISVGNKFKTQLNLLLDKLRSTGASFIRCIKPNLKMTSHHFEGAQILSQLQCSGMVSVL 698
F +VG +K L L+ LR+T +F+RCI PN + + + +L QL+C+G++ +
Sbjct: 649 MFRTVGQLYKESLTKLMATLRNTNPNFVRCIIPNHEKRAGKLDPHLVLDQLRCNGVLEGI 708
Query: 699 DLMQGGYPSRASFHELYNMYKKYMPDKLAR--LDPRLFCKALFKALGLNENDYKFGLTKV 756
+ + G+P+R F E Y+ P+ + + +D + C+ + +AL L+ N Y+ G +K+
Sbjct: 709 RICRQGFPNRIVFQEFRQRYEILTPNAIPKGFMDGKQACERMIRALELDPNLYRIGQSKI 768
Query: 757 FFRPGKFAEFDQIMKSDPDHLAELVKRV-NHWLTCSRWKKVQWCSLSVIKLKNKIKYRAE 815
FFR G A ++ + + V +L + K Q LS +K+ ++
Sbjct: 769 FFRAGVLAHLEEERDLKITDIIIFFQAVCRGYLARKAFAKKQQ-QLSALKV---LQRNCA 824
Query: 816 ACIKMQKTIRMWLCKRRHKPRIDGLVKVGTLKKRLDKFNEVVSVLKDGKPEMNKQIKNLE 875
A +K++ + W + KP L++V ++ L +E + +K+ + ++ +++ +E
Sbjct: 825 AYLKLRHW-QWWRVFTKVKP----LLQVTRQEEELQAKDEELLKVKEKQTKVEGELEEME 879
Query: 876 ISIDTLMAKIKSTMMTQEQIQKEYDALVKSSEELLSALQKKKQQ------------EEEA 923
L ++ + EQ+Q E + L +EE+ + L KKQ+ EEE
Sbjct: 880 RKHQQL---LEEKNILAEQLQAETE-LFAEAEEMRARLAAKKQELEEILHDLESRVEEEE 935
Query: 924 ERLRRIQEEMEKERKRREEDEKRRRKEEEERRMKLEM-----EAKRKQEEEERKKREDD- 977
ER + +Q E +K+ + +D + + EEE R KL++ EAK K+ EEE ED
Sbjct: 936 ERNQILQNE-KKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQN 994
Query: 978 -----EKRIQ----AEVEAQLARQ--------------------------KEEESQQQ-- 1000
EK++ AE +QLA + KEE+++Q+
Sbjct: 995 SKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELE 1054
Query: 1001 ---------------AVLEQERRDRELALRIAQSEAELISDEAQA-DLALRRNDGTRPKM 1044
+ E + + EL L++A+ E EL A+ D L +N+ +
Sbjct: 1055 KAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALK--- 1111
Query: 1045 TPEQMAKEMSEFLSRGPAVLATKAAAGTKKYDLSKWKYA---ELRDTINTSCDIELLAAC 1101
++ +++E + A++ A +K DLS+ A EL DT++T+ + L
Sbjct: 1112 VVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTK 1171
Query: 1102 REEFHRRLKVYHAWKSKN 1119
RE+ LK ++KN
Sbjct: 1172 REQEVAELKKALEEETKN 1189
Score = 55.8 bits (133), Expect = 3e-07
Identities = 44/237 (18%), Positives = 115/237 (48%), Gaps = 26/237 (10%)
Query: 806 LKNKIKYRAEACIKMQKTIRMWLCKRRHKPRIDGLVK--------VGTLKKRLDKFNEVV 857
L +++ +A A K++KT K R + +D L L+K+ KF++++
Sbjct: 1404 LSQRLEEKALAYDKLEKT------KNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLL 1457
Query: 858 SVLK-------DGKPEMNKQIKNLEISIDTLMAKIKSTMMTQEQIQKEYDALVKSSEELL 910
+ K + + + + E +L ++ + +E+ +++ L E+L+
Sbjct: 1458 AEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLM 1517
Query: 911 SALQKKKQQEEEAERLRRIQEEMEKERKRREEDEKRRRKEEEERRMKLE-----MEAKRK 965
S+ + E E+ +R E+ +E + + E+ + + E+ +++LE M+A+ +
Sbjct: 1518 SSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFE 1577
Query: 966 QEEEERKKREDDEKRIQAEVEAQLARQKEEESQQQAVLEQERRDRELALRIAQSEAE 1022
++ + R ++ +++KR+ + +L + E+E +Q+A+ ++ E+ L+ +++ E
Sbjct: 1578 RDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIE 1634
Score = 52.4 bits (124), Expect = 3e-06
Identities = 65/325 (20%), Positives = 148/325 (45%), Gaps = 39/325 (12%)
Query: 764 AEFDQIMKSDPD-----HLAELVKRVNHWLTCSRWKKVQWCSLSVIKLKNKIKYRAEACI 818
A+ + +M S D H E KR ++V+ + +L+++++ +A +
Sbjct: 1511 ADMEDLMSSKDDVGKNVHELEKSKRALE-------QQVEEMRTQLEELEDELQATEDAKL 1563
Query: 819 KMQKTIRMWLCKRRHKPRIDGLVKVGTLKKRL--DKFNEVVSVLKDGKPEMNKQI---KN 873
+++ + M K + + + + KKRL + E+ + L+D + + + K
Sbjct: 1564 RLE--VNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKK 1621
Query: 874 LEISIDTLMAKIKSTMMTQEQIQKEYDALVKSSEELLSALQKKK--------QQEEEAER 925
+EI + L A+I++ ++++ K+ L ++ L++ + Q +E ++
Sbjct: 1622 MEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKK 1681
Query: 926 LRRIQEEMEKERKRREEDEKRRRKEEEERRMKLEMEAKRKQEEEERKKREDDEKRIQAEV 985
L+ ++ E+ + ++ E+ RR E+ER E+ + + D+++R++A +
Sbjct: 1682 LKSLEAEILQLQEELASSERARRHAEQERD---ELADEITNSASGKSALLDEKRRLEARI 1738
Query: 986 EAQLARQKEEESQQQAVLEQERRDRELALRIAQSEAELISDEAQADLALRRNDGTRPKMT 1045
AQL + EEE +L R R+ L++ AEL ++ + A +++D R ++
Sbjct: 1739 -AQLEEELEEEQSNMELLND--RFRKTTLQVDTLNAELAAERS----AAQKSDNARQQL- 1790
Query: 1046 PEQMAKEMSEFLSRGPAVLATKAAA 1070
E+ KE+ L + +K A
Sbjct: 1791 -ERQNKELKAKLQELEGAVKSKFKA 1814
Score = 50.4 bits (119), Expect = 1e-05
Identities = 59/282 (20%), Positives = 127/282 (45%), Gaps = 34/282 (12%)
Query: 857 VSVLKDGKPEMNKQIKNLEISIDTLMAKIKSTMMTQEQIQKEYDALVKSSEE---LLSAL 913
V VL+ K E + K L+ + L AK+ + ++ ++ L + LL
Sbjct: 1240 VKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEA 1299
Query: 914 QKK-----KQQEEEAERLRRIQEEMEKERKRREEDEKRRRKEEEERRMKLEMEAKRKQEE 968
+KK K +L+ QE +++E +++ R R+ EEE+ + ++Q+E
Sbjct: 1300 EKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKN------SLQEQQE 1353
Query: 969 EERKKREDDEKRIQAEVEAQLARQKEEESQQQAVLEQERRDRELALRIAQSEAELISDEA 1028
EE + R++ EK++ A +++QLA K++ +E ++ L+ A++ ++ + ++A
Sbjct: 1354 EEEEARKNLEKQVLA-LQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKA 1412
Query: 1029 QADLALRRNDGTRPKMTPE------------QMAKEMSEFLSRGPAVLATKAAAGTKKYD 1076
LA + + T+ ++ E Q+A + + + +LA + + + +
Sbjct: 1413 ---LAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAE 1469
Query: 1077 LSKWKYAELRD----TINTSCDIELLAACREEFHRRLKVYHA 1114
AE R+ ++ + +E +EEF R+ K A
Sbjct: 1470 ERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRA 1511
Score = 45.8 bits (107), Expect = 3e-04
Identities = 70/331 (21%), Positives = 136/331 (41%), Gaps = 64/331 (19%)
Query: 886 KSTMMTQEQIQKEYDALVKSSEELLSALQKKKQQEEEAERLRRIQEEMEKERKRREE--- 942
K + Q+Q + L + + + L+ + +Q EEE L+ QEE E+ RK E+
Sbjct: 1308 KDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVL 1367
Query: 943 -------DEKRRRKEE-------EERRMKLEMEAKRKQEEEERK-----KREDDEKRIQA 983
D K++ ++ EE + KL +A+ + E K K E + R+Q
Sbjct: 1368 ALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQ 1427
Query: 984 EV---------EAQLAR--QKEEESQQQAVLEQERRDRELALRIAQSEAELISDEAQA-D 1031
E+ + Q+A +K+++ Q + E++ A ++EAE E +A
Sbjct: 1428 ELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALS 1487
Query: 1032 LALRRNDGTRPKMTPEQMAKEMSEFLSRGPAVLATKAAAGTKKYDLSKWKYA-------- 1083
LA + K E+ ++ + + ++++K G ++L K K A
Sbjct: 1488 LARALEEALEAK---EEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEM 1544
Query: 1084 -----ELRDTINTSCDIEL-----LAACREEFHRRLKVYHAWKSKNKKRNTETEQRAPKS 1133
EL D + + D +L + A + +F R L+ ++N E ++ K
Sbjct: 1545 RTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQT-------RDEQNEEKKRLLIKQ 1597
Query: 1134 VTDYDFAPFLNNSPQQNPAAQIPARQREIEM 1164
V + + L + +Q A ++ EI++
Sbjct: 1598 VRELEAE--LEDERKQRALAVASKKKMEIDL 1626
Score = 44.7 bits (104), Expect = 6e-04
Identities = 42/198 (21%), Positives = 95/198 (47%), Gaps = 25/198 (12%)
Query: 850 LDKFNEVVSVLKDGKPEMNKQIKNLE----------ISIDTLMAKI-------KSTMMTQ 892
LD+ + + + + E+ ++ N+E + +DTL A++ + + +
Sbjct: 1728 LDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNAR 1787
Query: 893 EQIQKEYDALVKSSEELLSALQKKKQQEEEA--ERLRRIQEEMEKERKRREEDEKR-RRK 949
+Q++++ L +EL A++ K + A ++ +++E++E+E K R K RR
Sbjct: 1788 QQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRT 1847
Query: 950 EEEERRMKLEMEAKRKQEEEERKKREDDEKRIQAEVEAQLARQKEEESQQQAVLEQERRD 1009
E++ + + +++E +R+ ++ +++ E R++ QL RQ EE ++ RR
Sbjct: 1848 EKKLKEIFMQVEDERRHADQYKEQMEKANARMK-----QLKRQLEEAEEEATRANASRRK 1902
Query: 1010 RELALRIAQSEAELISDE 1027
+ L A E +S E
Sbjct: 1903 LQRELDDATEANEGLSRE 1920
Score = 44.3 bits (103), Expect = 8e-04
Identities = 54/270 (20%), Positives = 112/270 (41%), Gaps = 38/270 (14%)
Query: 866 EMNKQIKNLEISIDTLMAKIKSTMMTQEQIQKEYDALVKSSEELLSALQKKKQ----QEE 921
E+ QI L+ ++ A + + +E +AL E+ L +++ +E+
Sbjct: 1115 ELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQ 1174
Query: 922 EAERLRRIQEEMEKERKRREEDEKRRRKEEEERRMKLEMEAKRKQEEEERKKR--EDDEK 979
E L++ EE K + + +D ++R E + +AKR + E+ K+ E D K
Sbjct: 1175 EVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNK 1234
Query: 980 RIQAEVEAQLARQKEEESQQQAVLEQERRDRELALRIAQSEAELISDEAQADLALRRNDG 1039
+ EV+ QQ E E + ++L ++ + A++ ++G
Sbjct: 1235 ELACEVKV----------LQQVKAESEHKRKKLDAQVQELHAKV-------------SEG 1271
Query: 1040 TRPKMTPEQMAKEMSEFLSRGPAVLATKAAAGTKKYDLSKWKYAELRDTINTSCDIELLA 1099
R ++ + A ++ L +L G K + ++L+DT ELL
Sbjct: 1272 DRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDT------QELL- 1324
Query: 1100 ACREEFHRRLKVYHAWKSKNKKRNTETEQR 1129
+EE ++L + + +++N+ EQ+
Sbjct: 1325 --QEETRQKLNLSSRIRQLEEEKNSLQEQQ 1352
Score = 38.5 bits (88), Expect = 0.042
Identities = 34/195 (17%), Positives = 82/195 (42%), Gaps = 5/195 (2%)
Query: 846 LKKRLDKFNEVVSVLKDGKPEMNKQIKNLEISIDTLMAKIKSTMMTQEQIQKEYDALVKS 905
L+ R+ + E + + +N + + + +DTL A++ + ++ L +
Sbjct: 1734 LEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQ 1793
Query: 906 SEELLSALQKKKQQEEEAERLRRIQEEMEKERKRREEDEKRRRKEEEERRMKLEMEAKRK 965
++EL K K QE E + + + + + E++ +E +ER ++ + +
Sbjct: 1794 NKEL-----KAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTE 1848
Query: 966 QEEEERKKREDDEKRIQAEVEAQLARQKEEESQQQAVLEQERRDRELALRIAQSEAELIS 1025
++ +E + +DE+R + + Q+ + Q + LE+ + A + +
Sbjct: 1849 KKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQRELD 1908
Query: 1026 DEAQADLALRRNDGT 1040
D +A+ L R T
Sbjct: 1909 DATEANEGLSREVST 1923
Score = 35.8 bits (81), Expect = 0.27
Identities = 36/159 (22%), Positives = 66/159 (41%), Gaps = 26/159 (16%)
Query: 841 VKVGTLKKRLDKFNEVVSVLKDGKPEMNKQIKNLEISIDTLMAKIKSTMMT--------- 891
++V TL L + + ++ +Q K L+ + L +KS
Sbjct: 1764 LQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKI 1823
Query: 892 ---QEQIQKEY------DALVKSSEELLSALQKKKQQEEEAERLRRIQEEMEKERKRREE 942
+EQ+++E + LV+ +E+ L + Q E+E + +E+MEK R ++
Sbjct: 1824 GQLEEQLEQEAKERAAANKLVRRTEKKLKEIFM--QVEDERRHADQYKEQMEKANARMKQ 1881
Query: 943 DEKRRRKEEEE------RRMKLEMEAKRKQEEEERKKRE 975
+++ + EEE R KL+ E E E RE
Sbjct: 1882 LKRQLEEAEEEATRANASRRKLQRELDDATEANEGLSRE 1920
>gi|153945715 myosin VC [Homo sapiens]
Length = 1742
Score = 484 bits (1245), Expect = e-136
Identities = 326/1021 (31%), Positives = 537/1021 (52%), Gaps = 106/1021 (10%)
Query: 61 DNCSLMYLNEATLLHNIKVRYSKDR-IYTYVANILIAVNPYFDIPKIYSSEAIKSYQGKS 119
D +L YL+E +LHN+++R+++ + IYTY IL+A+NPY +P IY I +Y G++
Sbjct: 71 DLTALSYLHEPAVLHNLRIRFAESKLIYTYSGIILVAMNPYKQLP-IYGDAIIHAYSGQN 129
Query: 120 LGTRPPHVFAIADKAFRDMKVLKMSQSIIVSGESGAGKTENTKFVLRYLT--ESYGTGQD 177
+G PH+FA+A++A++ M +QSIIVSGESGAGKT + ++ +RY G+
Sbjct: 130 MGDMDPHIFAVAEEAYKQMARNNRNQSIIVSGESGAGKTVSARYAMRYFATVSKSGSNAH 189
Query: 178 IDDRIVEANPLLEAFGNAKTVRNNNSSRFGKFVEIHFNEKSSVVGGFVSHYLLEKSRICV 237
++D+++ +NP+ EA GNAKT RN+NSSRFGK+ EI F+E++ ++G +S YLLEKSR+
Sbjct: 190 VEDKVLASNPITEAVGNAKTTRNDNSSRFGKYTEISFDEQNQIIGANMSTYLLEKSRVVF 249
Query: 238 QGKEERNYHIFYRLCAGASEDIREKLHLSSPDNFRYLNRGCTRYFANKETDKQILQNRKS 297
Q + ERNYHIFY+LCA A + + L L S + F Y G
Sbjct: 250 QSENERNYHIFYQLCASAQQSEFKHLKLGSAEEFNYTRMG-------------------- 289
Query: 298 PEYLKAGSMKDPLLDDHGDFIRMCTAMKKIGLDDEEKLDLFRVVAGVLHLGNIDFEEAGS 357
G+ ++D + + +G ++ ++D+F+++A +LHLGN+ G+
Sbjct: 290 ------GNTVIEGVNDRAEMVETQKTFTLLGFKEDFQMDVFKILAAILHLGNVQITAVGN 343
Query: 358 TSGGCNLKNKSAQSLEYCAELLGLDQDDLRVSLTTRVMLTTAGGTKGTVIKVPLKVEQAN 417
++ L+ ELLGL+ + L R ++T++ TV+K P+ QA
Sbjct: 344 ERSSV---SEDDSHLKVFCELLGLESGRVAQWLCNRKIVTSS----ETVVK-PMTRPQAV 395
Query: 418 NARDALAKTVYSHLFDHVVNRVNQCFPFETSSY-FIGVLDIAGFEYFEHNSFEQFCINYC 476
NARDALAK +Y+HLFD +V R+NQ F + FIGVLDI GFE F+ NSFEQFCINY
Sbjct: 396 NARDALAKKIYAHLFDFIVERINQALQFSGKQHTFIGVLDIYGFETFDVNSFEQFCINYA 455
Query: 477 NEKLQQFFNERILKEEQELYQKEGLGVNEVHYVDNQDCIDLIEAKLVGILDILDEENRLP 536
NEKLQQ FN + K EQE Y KE + + + DNQ IDLIEAK+ GIL++LDEE LP
Sbjct: 456 NEKLQQQFNMHVFKLEQEEYMKEDIPWTLIDFYDNQPVIDLIEAKM-GILELLDEECLLP 514
Query: 537 QPSDQHFTSAVHQKHKDHFRL-TIPRKSKLAVHRNIRDDEGFIIRHFAGAVCYETTQFVE 595
+D+++ ++ + L PR S + F+I+HFA V Y+ F+E
Sbjct: 515 HGTDENWLQKLYNNFVNRNPLFEKPRMS----------NTSFVIQHFADKVEYKCEGFLE 564
Query: 596 KNNDALHMSLESLICESRDKFIRELFES------------STNNNKDTKQKAGKLSFISV 643
KN D ++ L ++ S+ F+ + + K + K +V
Sbjct: 565 KNRDTVYDMLVEILRASKFHLCANFFQENPTPPSPFGSMITVKSAKQVIKPNSKHFRTTV 624
Query: 644 GNKFKTQLNLLLDKLRSTGASFIRCIKPNLKMTSHHFEGAQILSQLQCSGMVSVLDLMQG 703
G+KF++ L LL++ L +T ++RCIKPN + F+ +I+ QL+ G++ + +
Sbjct: 625 GSKFRSSLYLLMETLNATTPHYVRCIKPNDEKLPFEFDSKRIVQQLRACGVLETIRISAQ 684
Query: 704 GYPSRASFHELYNMYKKYM-PDKLARLDPRLFCKALFKALGLNENDYKFGLTKVFFRPGK 762
YPSR ++ E Y+ Y M +L+ D + CK + L + N Y+FG TK+FFR G+
Sbjct: 685 SYPSRWTYIEFYSRYGILMTKQELSFSDKKEVCKVVLHRLIQDSNQYQFGKTKIFFRAGQ 744
Query: 763 FAEFDQIMKSDPDHLAELV-KRVNHWLTCSRWKKVQWCSL----------SVIKLKNKIK 811
A +++ +V K + WL ++ + + +L +V K +
Sbjct: 745 VAYLEKLRLDKLRQSCVMVQKHMRGWLQRKKFLRERRAALIIQQYFRGQQTVRKAITAVA 804
Query: 812 YR-AEACIKMQKTIRMWLCKRRHKPRIDGLVKVGTL-----------KKRLDKFNEVVSV 859
+ A A I +QK R +L + ++ L+++ T+ ++R K E
Sbjct: 805 LKEAWAAIIIQKHCRGYLVRSLYQ-----LIRMATITMQAYSRGFLARRRYRKMLEEHKA 859
Query: 860 LKDGKPEMNKQIKNLEISIDTLMAKIKSTMMTQEQIQKEYDALVKSSEELLSALQK-KKQ 918
+ K + SI + I+ T Q ++QK+ + K + L+ L
Sbjct: 860 VILQKYARAWLARRRFQSIRRFVLNIQLTYRVQ-RLQKKLEDQNKENHGLVEKLTSLAAL 918
Query: 919 QEEEAERLRRIQEEMEK---ERKRREEDEKRRRKEEEERRMKL-----EMEAKRKQEEEE 970
+ + E++++++ E+EK R+ EE KR R EE+ KL E+E +++Q + +
Sbjct: 919 RAGDVEKIQKLEAELEKAATHRRNYEEKGKRYRDAVEEKLAKLQKHNSELETQKEQIQLK 978
Query: 971 RKKREDDEKRIQAEVEAQLARQKEEESQQQAVLEQ----ERRDRELALRIAQSEAELISD 1026
+++ ++ K + QL ++E +Q+ +LE+ + +D E ++ + E + + D
Sbjct: 979 LQEKTEELKEKMDNLTKQLFDDVQKEERQRMLLEKSFELKTQDYEKQIQSLKEEIKALKD 1038
Query: 1027 E 1027
E
Sbjct: 1039 E 1039
Score = 43.1 bits (100), Expect = 0.002
Identities = 40/168 (23%), Positives = 76/168 (45%), Gaps = 21/168 (12%)
Query: 867 MNKQIKNLEISIDTLMAKIKSTMMTQEQIQKEYDALVKSS------EELLSALQKKKQQ- 919
+N ++ +L I+ L + E I+ E L + ++ +S L+K+KQ
Sbjct: 1169 LNFKVVHLSQEINHLQKLFREENDINESIRHEVTRLTSENMMIPDFKQQISELEKQKQDL 1228
Query: 920 ----EEEAERLRRIQEEMEKERKRREEDEKRRRKEEEERRMKLEMEAKRKQEEEERKKRE 975
E+AE+++ EE+ + R +E+E +RK +EA+ + +E++K
Sbjct: 1229 EIRLNEQAEKMKGKLEELSNQLHRSQEEEGTQRK---------ALEAQNEIHTKEKEKLI 1279
Query: 976 DDEKRIQAEVEAQLARQKEEESQQQAVLEQERRDRELALRIAQSEAEL 1023
D + +Q E L +Q E ES+ + QE L R + E ++
Sbjct: 1280 DKIQEMQ-EASDHLKKQFETESEVKCNFRQEASRLTLENRDLEEELDM 1326
Score = 36.2 bits (82), Expect = 0.21
Identities = 36/169 (21%), Positives = 77/169 (45%), Gaps = 9/169 (5%)
Query: 849 RLDKFNEVVSVLKDGKPEMNKQIKNLEISIDTLMAKIK---STMMTQEQIQKEYDALVKS 905
RL N ++ K E+ KQ ++LEI ++ K+K + Q +E + +
Sbjct: 1203 RLTSENMMIPDFKQQISELEKQKQDLEIRLNEQAEKMKGKLEELSNQLHRSQEEEGTQRK 1262
Query: 906 SEELLSALQKKKQQEEEAERLRRIQEEMEKERKRRE-EDEKRRRKEEEERRMKLE---ME 961
+ E + + K++E+ ++++ +QE + +K+ E E E + +E R+ LE +E
Sbjct: 1263 ALEAQNEIH-TKEKEKLIDKIQEMQEASDHLKKQFETESEVKCNFRQEASRLTLENRDLE 1321
Query: 962 AKRKQEEEERKKREDDEKRIQAEV-EAQLARQKEEESQQQAVLEQERRD 1009
+ ++ KK +D K + + +A + +L+ +R D
Sbjct: 1322 EELDMKDRVIKKLQDQVKTLSKTIGKANDVHSSSGPKEYLGMLQYKRED 1370
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 480 bits (1236), Expect = e-135
Identities = 375/1200 (31%), Positives = 590/1200 (49%), Gaps = 163/1200 (13%)
Query: 7 VWAPHPTDGFQMGNIVDIGPDSLTIEPLNQKGKTFLALINQVFPAEEDSKKDVEDNCSLM 66
VW P GF+ +I + D + +E L + GK + + VED L
Sbjct: 36 VWVPSEKQGFEAASIKEEKGDEVVVE-LVENGKKVTVGKDDIQKMNPPKFSKVEDMAELT 94
Query: 67 YLNEATLLHNIKVRYSKDRIYTYVANILIAVNPYFDIPKIYSSEAIKSYQGKSLGTRPPH 126
LNEA++LHN++ RY IYTY + VNPY +P IYS + + Y+GK PPH
Sbjct: 95 CLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLP-IYSEKIVDMYKGKKRHEMPPH 153
Query: 127 VFAIADKAFRDMKVLKMSQSIIVSGESGAGKTENTKFVLRYLT----------ESYGTGQ 176
++AIAD A+R M + QSI+ +GESGAGKTENTK V++YL ++ TG+
Sbjct: 154 IYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKDTSITGE 213
Query: 177 DIDDRIVEANPLLEAFGNAKTVRNNNSSRFGKFVEIHFNEKSSVVGGFVSHYLLEKSRIC 236
++ ++++ANP+LEAFGNAKTV+N+NSSRFGKF+ I+F+ +VG + YLLEKSR
Sbjct: 214 -LEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAI 272
Query: 237 VQGKEERNYHIFYRLCAGASEDIREKLHLSSPDNFRYLNRGCTRYFANKETDKQILQNRK 296
Q ++ER +HIFY + AGA E +R L L +N+ +L+ G
Sbjct: 273 RQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLSNGFVPI--------------- 317
Query: 297 SPEYLKAGSMKDPLLDDHGDFIRMCTAMKKIGLDDEEKLDLFRVVAGVLHLGNIDFEEAG 356
P D F AM +G +EE+L + +VV+ VL LGNI F++
Sbjct: 318 ------------PAAQDDEMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKER 365
Query: 357 STSGGCNLKNKSAQSLEYCAELLGLDQDDLRVSLTTRVMLTTAGGTKGTVIKVPLKVEQA 416
+T N +AQ + L+G++ D TR +LT V++ EQA
Sbjct: 366 NTDQASMPDNTAAQKV---CHLMGINVTDF-----TRSILTPRIKVGRDVVQKAQTKEQA 417
Query: 417 NNARDALAKTVYSHLFDHVVNRVNQCFP--FETSSYFIGVLDIAGFEYFEHNSFEQFCIN 474
+ A +ALAK Y LF ++ RVN+ + F+G+LDIAGFE FE NSFEQ CIN
Sbjct: 418 DFAVEALAKATYERLFRWILTRVNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQLCIN 477
Query: 475 YCNEKLQQFFNERILKEEQELYQKEGLGVNEVHY-VDNQDCIDLIEA--KLVGILDILDE 531
Y NEKLQQ FN + EQE YQ+EG+ N + + +D Q CI+LIE G+L +LDE
Sbjct: 478 YTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDE 537
Query: 532 ENRLPQPSDQHFTSAVHQKHKDHFRLTIPRKSKLAVHRNIRDDEGFIIRHFAGAVCYETT 591
E P+ +D+ F + + H + P++ ++D F I H+AG V Y +
Sbjct: 538 ECWFPKATDKSFVEKLCTEQGSHPKFQKPKQ--------LKDKTEFSIIHYAGKVDYNAS 589
Query: 592 QFVEKNNDALHMSLESLICESRDKFIRELFE------------SSTNNNKDTKQKAGKLS 639
++ KN D L+ ++ SL+ S DKF+ +L++ T ++ + K K
Sbjct: 590 AWLTKNMDPLNDNVTSLLNASSDKFVADLWKDVDRIVGLDQMAKMTESSLPSASKTKKGM 649
Query: 640 FISVGNKFKTQLNLLLDKLRSTGASFIRCIKPNLKMTSHHFEGAQILSQLQCSGMVSVLD 699
F +VG +K QL L+ LR+T +F+RCI PN + S + +L QL+C+G++ +
Sbjct: 650 FRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIR 709
Query: 700 LMQGGYPSRASFHELYNMYKKYMPDKLAR--LDPRLFCKALFKALGLNENDYKFGLTKVF 757
+ + G+P+R F E Y+ + + + +D + C + KAL L+ N Y+ G +K+F
Sbjct: 710 ICRQGFPNRIVFQEFRQRYEILAANAIPKGFMDGKQACILMIKALELDPNLYRIGQSKIF 769
Query: 758 FRPGKFAEFDQIMK-SDPDHLAELVKRVNHWLTCSRWKKVQWCSLSVIKLKNKIKYRAEA 816
FR G A ++ D + +L + K Q L+ +K+ I+ A
Sbjct: 770 FRTGVLAHLEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQ-QLTAMKV---IQRNCAA 825
Query: 817 CIKMQKTIRMWLCKRRHKPRIDGLVKVGTLKKRLDKFNEVVSVLKDGKPEMNKQIKNLEI 876
+K+ + + W + KP L++V ++ + + + K+ + + ++K LE
Sbjct: 826 YLKL-RNWQWWRLFTKVKP----LLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQ 880
Query: 877 SIDTLMAKIKSTMMTQEQIQKEYDALVKSSEELLSALQKKKQQEEEA--ERLRRIQEE-- 932
L + + QEQ+Q E + L +EE+ L KKQ+ EE E R++EE
Sbjct: 881 KHSQL---TEEKNLLQEQLQAETE-LYAEAEEMRVRLAAKKQELEEILHEMEARLEEEED 936
Query: 933 ----MEKERKRREE---DEKRRRKEEEERRMKLEM-----EAKRKQEEEERKKREDDEKR 980
++ ERK+ + D + + +EEE R KL++ EAK K+ E+E +D +
Sbjct: 937 RGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNK 996
Query: 981 IQAE------------------------------------VEAQLARQKEEESQQQAVLE 1004
+ E E ++ +KEE+S+Q+ LE
Sbjct: 997 LSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQE--LE 1054
Query: 1005 QERRDRE------------LALRIAQSEAELISDEAQADLALRR-NDGTRPKMTPEQMAK 1051
+ +R E L +IA+ + +L E + AL R +D K + +
Sbjct: 1055 KLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIR 1114
Query: 1052 EMSEFLSRGPAVLATKAAAGTK----KYDLSKWKYA---ELRDTINTSCDIELLAACREE 1104
E+ +S L ++ AA K K DL + A EL DT++++ + L A RE+
Sbjct: 1115 ELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQ 1174
Score = 67.8 bits (164), Expect = 6e-11
Identities = 47/193 (24%), Positives = 94/193 (48%), Gaps = 9/193 (4%)
Query: 841 VKVGTLKKRLDKFNEVVSVLKDGKPEMNKQIKNLEISIDTLMAKIKSTMMTQEQIQKEYD 900
+++ KK+L F V L++GK K+I+NL + A T+ ++Q+E D
Sbjct: 1371 IQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELD 1430
Query: 901 ALV---KSSEELLSALQKKKQQEEEAERLRRIQEEMEKERKRREEDEKRRRKEEEERRMK 957
LV + +L+S L+KK+++ ++ + EE K +E ++ + E+
Sbjct: 1431 DLVVDLDNQRQLVSNLEKKQRKFDQL-----LAEEKNISSKYADERDRAEAEAREKETKA 1485
Query: 958 LEMEAKRKQEEEERKKREDDEKRIQAEVEAQLARQKEEESQQQAVLEQERRDRELALRIA 1017
L + ++ E +++ E K ++AE+E L K++ + LE+ +R E +
Sbjct: 1486 LSLARALEEALEAKEELERTNKMLKAEME-DLVSSKDDVGKNVHELEKSKRALETQMEEM 1544
Query: 1018 QSEAELISDEAQA 1030
+++ E + DE QA
Sbjct: 1545 KTQLEELEDELQA 1557
Score = 59.7 bits (143), Expect = 2e-08
Identities = 59/246 (23%), Positives = 112/246 (45%), Gaps = 27/246 (10%)
Query: 806 LKNKIKYRAEACIKMQKTIRMWLCKRRHKPRIDGLVK--------VGTLKKRLDKFNEVV 857
L + + +A A K++KT K R + +D LV V L+K+ KF++++
Sbjct: 1404 LTQQYEEKAAAYDKLEKT------KNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLL 1457
Query: 858 SVLK-------DGKPEMNKQIKNLEISIDTLMAKIKSTMMTQEQIQKEYDALVKSSEELL 910
+ K D + + + E +L ++ + +E++++ L E+L+
Sbjct: 1458 AEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLV 1517
Query: 911 SALQKKKQQEEEAERLRRIQEEMEKERKRREEDEKRRRKEEEERRMKLEMEAKRKQEEEE 970
S+ + E E+ +R E +E K + E+ + + E+ +++LE+ + + + E
Sbjct: 1518 SSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFE 1577
Query: 971 RKKREDDEKRIQAEVEAQLARQKEEESQQQAVLEQERRDRELALRIAQS-EAELISDEAQ 1029
R + DE+ E QL RQ E + LE ER+ R LA + E +L E Q
Sbjct: 1578 RDLQARDEQ--NEEKRRQLQRQLHE---YETELEDERKQRALAAAAKKKLEGDLKDLELQ 1632
Query: 1030 ADLALR 1035
AD A++
Sbjct: 1633 ADSAIK 1638
Score = 54.7 bits (130), Expect = 6e-07
Identities = 53/226 (23%), Positives = 99/226 (43%), Gaps = 16/226 (7%)
Query: 847 KKRLDKFNEVVSV----LKDGKPEMNKQIKNLEISIDTLMAKIKSTMMTQEQIQKEYDAL 902
K+ L++ N+++ L K ++ K + LE S L +++ E+++ E A
Sbjct: 1499 KEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQAT 1558
Query: 903 VKSSEELLSALQKKKQQEEEAERLRRIQEEMEKERKRREEDEKRRRKEEEERRMKLEMEA 962
+ L +Q K Q E + R Q E ++ + +R+ E E+E ++ L A
Sbjct: 1559 EDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAA 1618
Query: 963 KRKQEEEERKKREDDEKRIQAEVEA--QLARQKEEESQQQAVLEQERRDRELALRIAQS- 1019
K+K E + + + I+ EA QL + + + Q LE R R+ A+
Sbjct: 1619 KKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKEN 1678
Query: 1020 -------EAELISDEAQADLALRRNDGTRPKMTPEQMAKEMSEFLS 1058
EA+L+ + Q DLA + + E++A+E++ LS
Sbjct: 1679 EKKAKSLEADLM--QLQEDLAAAERARKQADLEKEELAEELASSLS 1722
Score = 51.6 bits (122), Expect = 5e-06
Identities = 52/205 (25%), Positives = 95/205 (46%), Gaps = 24/205 (11%)
Query: 821 QKTIRMWLCKRRHKPRIDGL-VKVGTLKKRLDKFNEVVSVLKDGKPEMNKQIKNLEISID 879
+K + K +H+ I L V++ +K + ++ L+ + ++QI +L+ I
Sbjct: 1020 EKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIA 1079
Query: 880 TLMAKIKSTMMTQEQIQKEYDALVKSSEELLSALQKKKQQEEEAERLRRIQEEMEKERKR 939
L ++ +E++Q AL + +E+ K+ E + +QE+++ ER
Sbjct: 1080 ELKMQLAKK---EEELQA---ALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAA 1133
Query: 940 REEDEKRRRKEEEE-RRMKLEME-------------AKRKQEEEERKKREDDEKRIQAEV 985
R + EK++R EE +K E+E AKR+QE KK D+E R E
Sbjct: 1134 RNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSH-EA 1192
Query: 986 EAQLARQKEEESQQQAV--LEQERR 1008
+ Q RQK ++ ++ LEQ +R
Sbjct: 1193 QVQEMRQKHAQAVEELTEQLEQFKR 1217
Score = 49.3 bits (116), Expect = 2e-05
Identities = 50/216 (23%), Positives = 100/216 (46%), Gaps = 34/216 (15%)
Query: 866 EMNKQIKNLEISIDTLMAKIKSTMMTQEQIQKEYDALVKSSEELLSALQKKKQQEEEAER 925
E K+ K+LE + L + + ++Q E + L +EEL S+L + ++E R
Sbjct: 1677 ENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEEL---AEELASSLSGRNALQDEKRR 1733
Query: 926 LR----RIQEEMEKERKRREEDEKRRRKEEE-----------ERRMKLEMEAKRKQEE-- 968
L +++EE+E+E+ E R RK + ER + E+ R+Q E
Sbjct: 1734 LEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQ 1793
Query: 969 --EERKKREDDEKRIQAEVEAQLARQKEEESQQQAVLEQERRDRELALRIAQSEAELISD 1026
E R K + E ++++ ++ +A + + +Q + +EQE R+++ A + + + D
Sbjct: 1794 NKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQK-----D 1848
Query: 1027 EAQADLALRRNDGTRPKMTPEQMAKEMSEFLSRGPA 1062
+ ++ L+ D +MA++ E +G A
Sbjct: 1849 KKLKEILLQVED-------ERKMAEQYKEQAEKGNA 1877
Score = 46.6 bits (109), Expect = 2e-04
Identities = 75/359 (20%), Positives = 149/359 (41%), Gaps = 77/359 (21%)
Query: 847 KKRLD-KFNEVVSVLKDG---KPEMNKQIKNLEISIDTLMAKI-----------KSTMMT 891
KK+L+ + E+ S DG + E+N ++ L+ ++++ + K
Sbjct: 1254 KKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASL 1313
Query: 892 QEQIQKEYDALVKSSEELLSALQKKKQQEEEAERLR-RIQEEMEKERKRRE--------- 941
Q+Q + L + + + L+ K +Q EEE L+ ++ EEME ++
Sbjct: 1314 SSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQL 1373
Query: 942 EDEKRRRK---------EEEERRMKLEMEAKRKQEEEER---KKREDDEKRIQAEVEAQL 989
D K++ + EE ++R + E+E +Q EE+ K E + R+Q E++ +
Sbjct: 1374 SDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLV 1433
Query: 990 ARQKEEESQQQAVLEQERRDRELALRIAQSE--AELISDEAQADLALRRNDGTRPKMTPE 1047
+ ++Q+Q V E++ R+ +A+ + + +DE A R T+
Sbjct: 1434 V---DLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLAR 1490
Query: 1048 QM--AKEMSEFLSRGPAVL--------ATKAAAGTKKYDLSKWKYA-------------E 1084
+ A E E L R +L ++K G ++L K K A E
Sbjct: 1491 ALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEE 1550
Query: 1085 LRDTINTSCDIEL-----LAACREEFHRRLKVYHAWKSKNKKRNTETEQRAPKSVTDYD 1138
L D + + D +L + A + +F R L+ ++N E ++ + + +Y+
Sbjct: 1551 LEDELQATEDAKLRLEVNMQALKGQFERDLQA-------RDEQNEEKRRQLQRQLHEYE 1602
Score = 46.6 bits (109), Expect = 2e-04
Identities = 44/212 (20%), Positives = 99/212 (46%), Gaps = 27/212 (12%)
Query: 842 KVGTLKKRLDKFNEVVSVLKDGKPEMNKQIKNLEISIDTLMAKIKSTMMTQEQIQK---- 897
++ L++ L++ + + D + +Q + L + T + + ++Q+++
Sbjct: 1737 RIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKE 1796
Query: 898 ------EYDALVKSS-EELLSALQKKKQQEEEAERLRRIQEEMEKE-RKRREEDEKRRRK 949
E + VKS + ++AL+ K Q ++E++E+E R+++ + ++K
Sbjct: 1797 LRSKLHEMEGAVKSKFKSTIAALEAKIAQ---------LEEQVEQEAREKQAATKSLKQK 1847
Query: 950 EEEERRMKLEMEAKRKQEEEERKKREDDEKRIQAEVEAQLARQKEEESQQQAVLEQERRD 1009
+++ + + L++E +RK E+ +++ E R++ QL RQ EE ++ + RR
Sbjct: 1848 DKKLKEILLQVEDERKMAEQYKEQAEKGNARVK-----QLKRQLEEAEEESQRINANRRK 1902
Query: 1010 RELALRIAQSEAELISDEAQA-DLALRRNDGT 1040
+ L A E + E A LRR + T
Sbjct: 1903 LQRELDEATESNEAMGREVNALKSKLRRGNET 1934
Score = 46.2 bits (108), Expect = 2e-04
Identities = 39/173 (22%), Positives = 85/173 (49%), Gaps = 11/173 (6%)
Query: 863 GKPEMNKQIKNLEISIDTLMAKIKSTMMTQEQIQKEYDALVKSSEELLSALQKKKQQEEE 922
G+ E KQ++ L+ + +++ ++++I K ++ L + L + ++
Sbjct: 1639 GREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAA 1698
Query: 923 AERLRRIQEEMEKERKRREEDEK---RRRKEEEERRMKLEMEAKRKQEEEERKKREDDEK 979
AER R+ Q ++EKE E R ++E+RR++ + ++ EEE+ E
Sbjct: 1699 AERARK-QADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSD 1757
Query: 980 RI-----QAE-VEAQLARQKEEESQQQAVLEQ-ERRDRELALRIAQSEAELIS 1025
R+ QAE + +LA ++ + ++ +Q ER+++EL ++ + E + S
Sbjct: 1758 RVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKS 1810
Score = 45.1 bits (105), Expect = 4e-04
Identities = 47/225 (20%), Positives = 108/225 (48%), Gaps = 30/225 (13%)
Query: 838 DGLVKVGTLKKRLDKFNEVVSVLKDGKPEMNKQIKNLEISIDTLMAKIKSTM---MTQEQ 894
+ L K+ L+ + E + + + + KQ ++L ++ L +++ T+ TQ++
Sbjct: 1108 NALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQE 1167
Query: 895 I----QKEYDALVKSSEELLSA--LQKKKQQEEEAERLRRIQEEMEKERKRREEDEKRRR 948
+ ++E L K+ +E + Q ++ +++ A+ + + E++E+ ++ + +K ++
Sbjct: 1168 LRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQ 1227
Query: 949 ---KEEEERRMKLEMEAKRKQEEEERKKRED-----------DEKRIQAEVEAQLAR-QK 993
KE + +L + + KQE E +KK+ + D +R +AE+ ++ + Q
Sbjct: 1228 TLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQN 1287
Query: 994 EEESQQQAVLEQERRDRELALRIA------QSEAELISDEAQADL 1032
E ES + E E + +LA +A Q EL+ +E + L
Sbjct: 1288 EVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKL 1332
Score = 45.1 bits (105), Expect = 4e-04
Identities = 46/192 (23%), Positives = 87/192 (45%), Gaps = 43/192 (22%)
Query: 893 EQIQKEYDALVKSSEELLSALQKKKQQEEEAERLRRIQEEMEKERKRREE------DEKR 946
+ ++ + D+ +K EE + L+K + Q ++ Q E+E R R+E + ++
Sbjct: 1627 KDLELQADSAIKGREEAIKQLRKLQAQ------MKDFQRELEDARASRDEIFATAKENEK 1680
Query: 947 RRKEEEERRMKLE-----MEAKRKQ---EEEE-----------RKKREDDEKRIQAEVEA 987
+ K E M+L+ E RKQ E+EE R +D+++R++A + A
Sbjct: 1681 KAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARI-A 1739
Query: 988 QLARQKEEESQQQAVLEQERRDRELALRIAQSEAELISDEAQADLALRRNDGTRPKMTPE 1047
QL + EEE + +R A +AE +S+E LA R+ + + +
Sbjct: 1740 QLEEELEEEQGNMEAMSDR-------VRKATQQAEQLSNE----LATERSTAQKNESARQ 1788
Query: 1048 QMAKEMSEFLSR 1059
Q+ ++ E S+
Sbjct: 1789 QLERQNKELRSK 1800
Score = 38.9 bits (89), Expect = 0.032
Identities = 61/324 (18%), Positives = 135/324 (41%), Gaps = 65/324 (20%)
Query: 845 TLKKRLDKFNEVVSVLKDGKPEMNKQIKNLEISIDTLMAKIKSTMMTQEQIQKEYDALVK 904
T + ++ K + + V+ D +++K+ K LE I L + +E+ K L
Sbjct: 975 TAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAE----EEEKAKNLTKLKN 1030
Query: 905 SSEELLSALQKKKQQEE----EAERLRRIQE------------------EMEKERKRREE 942
E ++S L+ + ++EE E E+L+R E E++ + ++EE
Sbjct: 1031 KHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEE 1090
Query: 943 ----------DEKRRRKEEEERRMKLEMEAKRKQEEEE-----RKKREDDEKRIQAEVEA 987
DE ++ ++ +LE QE+ + R K E ++ + E+EA
Sbjct: 1091 ELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEA 1150
Query: 988 QLARQKEEESQQQAVLEQE---RRDRELALRIAQSEAELISDEAQADLALRRNDGTRPKM 1044
+ + E++ +QE +R++E+ + + E S EAQ +++
Sbjct: 1151 --LKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKH-----AQ 1203
Query: 1045 TPEQMAKEMSEFLSRGPAVLATKAAAGTKKYDLSKWKYAELRDTINTSCDIELLAACREE 1104
E++ +++ +F K A K +L K K ++ + + ++ +L ++E
Sbjct: 1204 AVEELTEQLEQF----------KRA----KANLDKNKQTLEKENADLAGELRVLGQAKQE 1249
Query: 1105 FHRRLKVYHAWKSKNKKRNTETEQ 1128
+ K A + + + ++ E+
Sbjct: 1250 VEHKKKKLEAQVQELQSKCSDGER 1273
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 480 bits (1236), Expect = e-135
Identities = 375/1200 (31%), Positives = 590/1200 (49%), Gaps = 163/1200 (13%)
Query: 7 VWAPHPTDGFQMGNIVDIGPDSLTIEPLNQKGKTFLALINQVFPAEEDSKKDVEDNCSLM 66
VW P GF+ +I + D + +E L + GK + + VED L
Sbjct: 36 VWVPSEKQGFEAASIKEEKGDEVVVE-LVENGKKVTVGKDDIQKMNPPKFSKVEDMAELT 94
Query: 67 YLNEATLLHNIKVRYSKDRIYTYVANILIAVNPYFDIPKIYSSEAIKSYQGKSLGTRPPH 126
LNEA++LHN++ RY IYTY + VNPY +P IYS + + Y+GK PPH
Sbjct: 95 CLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLP-IYSEKIVDMYKGKKRHEMPPH 153
Query: 127 VFAIADKAFRDMKVLKMSQSIIVSGESGAGKTENTKFVLRYLT----------ESYGTGQ 176
++AIAD A+R M + QSI+ +GESGAGKTENTK V++YL ++ TG+
Sbjct: 154 IYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKDTSITGE 213
Query: 177 DIDDRIVEANPLLEAFGNAKTVRNNNSSRFGKFVEIHFNEKSSVVGGFVSHYLLEKSRIC 236
++ ++++ANP+LEAFGNAKTV+N+NSSRFGKF+ I+F+ +VG + YLLEKSR
Sbjct: 214 -LEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAI 272
Query: 237 VQGKEERNYHIFYRLCAGASEDIREKLHLSSPDNFRYLNRGCTRYFANKETDKQILQNRK 296
Q ++ER +HIFY + AGA E +R L L +N+ +L+ G
Sbjct: 273 RQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLSNGFVPI--------------- 317
Query: 297 SPEYLKAGSMKDPLLDDHGDFIRMCTAMKKIGLDDEEKLDLFRVVAGVLHLGNIDFEEAG 356
P D F AM +G +EE+L + +VV+ VL LGNI F++
Sbjct: 318 ------------PAAQDDEMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKER 365
Query: 357 STSGGCNLKNKSAQSLEYCAELLGLDQDDLRVSLTTRVMLTTAGGTKGTVIKVPLKVEQA 416
+T N +AQ + L+G++ D TR +LT V++ EQA
Sbjct: 366 NTDQASMPDNTAAQKV---CHLMGINVTDF-----TRSILTPRIKVGRDVVQKAQTKEQA 417
Query: 417 NNARDALAKTVYSHLFDHVVNRVNQCFP--FETSSYFIGVLDIAGFEYFEHNSFEQFCIN 474
+ A +ALAK Y LF ++ RVN+ + F+G+LDIAGFE FE NSFEQ CIN
Sbjct: 418 DFAVEALAKATYERLFRWILTRVNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQLCIN 477
Query: 475 YCNEKLQQFFNERILKEEQELYQKEGLGVNEVHY-VDNQDCIDLIEA--KLVGILDILDE 531
Y NEKLQQ FN + EQE YQ+EG+ N + + +D Q CI+LIE G+L +LDE
Sbjct: 478 YTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDE 537
Query: 532 ENRLPQPSDQHFTSAVHQKHKDHFRLTIPRKSKLAVHRNIRDDEGFIIRHFAGAVCYETT 591
E P+ +D+ F + + H + P++ ++D F I H+AG V Y +
Sbjct: 538 ECWFPKATDKSFVEKLCTEQGSHPKFQKPKQ--------LKDKTEFSIIHYAGKVDYNAS 589
Query: 592 QFVEKNNDALHMSLESLICESRDKFIRELFE------------SSTNNNKDTKQKAGKLS 639
++ KN D L+ ++ SL+ S DKF+ +L++ T ++ + K K
Sbjct: 590 AWLTKNMDPLNDNVTSLLNASSDKFVADLWKDVDRIVGLDQMAKMTESSLPSASKTKKGM 649
Query: 640 FISVGNKFKTQLNLLLDKLRSTGASFIRCIKPNLKMTSHHFEGAQILSQLQCSGMVSVLD 699
F +VG +K QL L+ LR+T +F+RCI PN + S + +L QL+C+G++ +
Sbjct: 650 FRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIR 709
Query: 700 LMQGGYPSRASFHELYNMYKKYMPDKLAR--LDPRLFCKALFKALGLNENDYKFGLTKVF 757
+ + G+P+R F E Y+ + + + +D + C + KAL L+ N Y+ G +K+F
Sbjct: 710 ICRQGFPNRIVFQEFRQRYEILAANAIPKGFMDGKQACILMIKALELDPNLYRIGQSKIF 769
Query: 758 FRPGKFAEFDQIMK-SDPDHLAELVKRVNHWLTCSRWKKVQWCSLSVIKLKNKIKYRAEA 816
FR G A ++ D + +L + K Q L+ +K+ I+ A
Sbjct: 770 FRTGVLAHLEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQ-QLTAMKV---IQRNCAA 825
Query: 817 CIKMQKTIRMWLCKRRHKPRIDGLVKVGTLKKRLDKFNEVVSVLKDGKPEMNKQIKNLEI 876
+K+ + + W + KP L++V ++ + + + K+ + + ++K LE
Sbjct: 826 YLKL-RNWQWWRLFTKVKP----LLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQ 880
Query: 877 SIDTLMAKIKSTMMTQEQIQKEYDALVKSSEELLSALQKKKQQEEEA--ERLRRIQEE-- 932
L + + QEQ+Q E + L +EE+ L KKQ+ EE E R++EE
Sbjct: 881 KHSQL---TEEKNLLQEQLQAETE-LYAEAEEMRVRLAAKKQELEEILHEMEARLEEEED 936
Query: 933 ----MEKERKRREE---DEKRRRKEEEERRMKLEM-----EAKRKQEEEERKKREDDEKR 980
++ ERK+ + D + + +EEE R KL++ EAK K+ E+E +D +
Sbjct: 937 RGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNK 996
Query: 981 IQAE------------------------------------VEAQLARQKEEESQQQAVLE 1004
+ E E ++ +KEE+S+Q+ LE
Sbjct: 997 LSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQE--LE 1054
Query: 1005 QERRDRE------------LALRIAQSEAELISDEAQADLALRR-NDGTRPKMTPEQMAK 1051
+ +R E L +IA+ + +L E + AL R +D K + +
Sbjct: 1055 KLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIR 1114
Query: 1052 EMSEFLSRGPAVLATKAAAGTK----KYDLSKWKYA---ELRDTINTSCDIELLAACREE 1104
E+ +S L ++ AA K K DL + A EL DT++++ + L A RE+
Sbjct: 1115 ELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQ 1174
Score = 67.8 bits (164), Expect = 6e-11
Identities = 47/193 (24%), Positives = 94/193 (48%), Gaps = 9/193 (4%)
Query: 841 VKVGTLKKRLDKFNEVVSVLKDGKPEMNKQIKNLEISIDTLMAKIKSTMMTQEQIQKEYD 900
+++ KK+L F V L++GK K+I+NL + A T+ ++Q+E D
Sbjct: 1371 IQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELD 1430
Query: 901 ALV---KSSEELLSALQKKKQQEEEAERLRRIQEEMEKERKRREEDEKRRRKEEEERRMK 957
LV + +L+S L+KK+++ ++ + EE K +E ++ + E+
Sbjct: 1431 DLVVDLDNQRQLVSNLEKKQRKFDQL-----LAEEKNISSKYADERDRAEAEAREKETKA 1485
Query: 958 LEMEAKRKQEEEERKKREDDEKRIQAEVEAQLARQKEEESQQQAVLEQERRDRELALRIA 1017
L + ++ E +++ E K ++AE+E L K++ + LE+ +R E +
Sbjct: 1486 LSLARALEEALEAKEELERTNKMLKAEME-DLVSSKDDVGKNVHELEKSKRALETQMEEM 1544
Query: 1018 QSEAELISDEAQA 1030
+++ E + DE QA
Sbjct: 1545 KTQLEELEDELQA 1557
Score = 59.7 bits (143), Expect = 2e-08
Identities = 59/246 (23%), Positives = 112/246 (45%), Gaps = 27/246 (10%)
Query: 806 LKNKIKYRAEACIKMQKTIRMWLCKRRHKPRIDGLVK--------VGTLKKRLDKFNEVV 857
L + + +A A K++KT K R + +D LV V L+K+ KF++++
Sbjct: 1404 LTQQYEEKAAAYDKLEKT------KNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLL 1457
Query: 858 SVLK-------DGKPEMNKQIKNLEISIDTLMAKIKSTMMTQEQIQKEYDALVKSSEELL 910
+ K D + + + E +L ++ + +E++++ L E+L+
Sbjct: 1458 AEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLV 1517
Query: 911 SALQKKKQQEEEAERLRRIQEEMEKERKRREEDEKRRRKEEEERRMKLEMEAKRKQEEEE 970
S+ + E E+ +R E +E K + E+ + + E+ +++LE+ + + + E
Sbjct: 1518 SSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFE 1577
Query: 971 RKKREDDEKRIQAEVEAQLARQKEEESQQQAVLEQERRDRELALRIAQS-EAELISDEAQ 1029
R + DE+ E QL RQ E + LE ER+ R LA + E +L E Q
Sbjct: 1578 RDLQARDEQ--NEEKRRQLQRQLHE---YETELEDERKQRALAAAAKKKLEGDLKDLELQ 1632
Query: 1030 ADLALR 1035
AD A++
Sbjct: 1633 ADSAIK 1638
Score = 54.7 bits (130), Expect = 6e-07
Identities = 53/226 (23%), Positives = 99/226 (43%), Gaps = 16/226 (7%)
Query: 847 KKRLDKFNEVVSV----LKDGKPEMNKQIKNLEISIDTLMAKIKSTMMTQEQIQKEYDAL 902
K+ L++ N+++ L K ++ K + LE S L +++ E+++ E A
Sbjct: 1499 KEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQAT 1558
Query: 903 VKSSEELLSALQKKKQQEEEAERLRRIQEEMEKERKRREEDEKRRRKEEEERRMKLEMEA 962
+ L +Q K Q E + R Q E ++ + +R+ E E+E ++ L A
Sbjct: 1559 EDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAA 1618
Query: 963 KRKQEEEERKKREDDEKRIQAEVEA--QLARQKEEESQQQAVLEQERRDRELALRIAQS- 1019
K+K E + + + I+ EA QL + + + Q LE R R+ A+
Sbjct: 1619 KKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKEN 1678
Query: 1020 -------EAELISDEAQADLALRRNDGTRPKMTPEQMAKEMSEFLS 1058
EA+L+ + Q DLA + + E++A+E++ LS
Sbjct: 1679 EKKAKSLEADLM--QLQEDLAAAERARKQADLEKEELAEELASSLS 1722
Score = 51.6 bits (122), Expect = 5e-06
Identities = 52/205 (25%), Positives = 95/205 (46%), Gaps = 24/205 (11%)
Query: 821 QKTIRMWLCKRRHKPRIDGL-VKVGTLKKRLDKFNEVVSVLKDGKPEMNKQIKNLEISID 879
+K + K +H+ I L V++ +K + ++ L+ + ++QI +L+ I
Sbjct: 1020 EKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIA 1079
Query: 880 TLMAKIKSTMMTQEQIQKEYDALVKSSEELLSALQKKKQQEEEAERLRRIQEEMEKERKR 939
L ++ +E++Q AL + +E+ K+ E + +QE+++ ER
Sbjct: 1080 ELKMQLAKK---EEELQA---ALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAA 1133
Query: 940 REEDEKRRRKEEEE-RRMKLEME-------------AKRKQEEEERKKREDDEKRIQAEV 985
R + EK++R EE +K E+E AKR+QE KK D+E R E
Sbjct: 1134 RNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSH-EA 1192
Query: 986 EAQLARQKEEESQQQAV--LEQERR 1008
+ Q RQK ++ ++ LEQ +R
Sbjct: 1193 QVQEMRQKHAQAVEELTEQLEQFKR 1217
Score = 49.3 bits (116), Expect = 2e-05
Identities = 50/216 (23%), Positives = 100/216 (46%), Gaps = 34/216 (15%)
Query: 866 EMNKQIKNLEISIDTLMAKIKSTMMTQEQIQKEYDALVKSSEELLSALQKKKQQEEEAER 925
E K+ K+LE + L + + ++Q E + L +EEL S+L + ++E R
Sbjct: 1677 ENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEEL---AEELASSLSGRNALQDEKRR 1733
Query: 926 LR----RIQEEMEKERKRREEDEKRRRKEEE-----------ERRMKLEMEAKRKQEE-- 968
L +++EE+E+E+ E R RK + ER + E+ R+Q E
Sbjct: 1734 LEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQ 1793
Query: 969 --EERKKREDDEKRIQAEVEAQLARQKEEESQQQAVLEQERRDRELALRIAQSEAELISD 1026
E R K + E ++++ ++ +A + + +Q + +EQE R+++ A + + + D
Sbjct: 1794 NKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQK-----D 1848
Query: 1027 EAQADLALRRNDGTRPKMTPEQMAKEMSEFLSRGPA 1062
+ ++ L+ D +MA++ E +G A
Sbjct: 1849 KKLKEILLQVED-------ERKMAEQYKEQAEKGNA 1877
Score = 46.6 bits (109), Expect = 2e-04
Identities = 75/359 (20%), Positives = 149/359 (41%), Gaps = 77/359 (21%)
Query: 847 KKRLD-KFNEVVSVLKDG---KPEMNKQIKNLEISIDTLMAKI-----------KSTMMT 891
KK+L+ + E+ S DG + E+N ++ L+ ++++ + K
Sbjct: 1254 KKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASL 1313
Query: 892 QEQIQKEYDALVKSSEELLSALQKKKQQEEEAERLR-RIQEEMEKERKRRE--------- 941
Q+Q + L + + + L+ K +Q EEE L+ ++ EEME ++
Sbjct: 1314 SSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQL 1373
Query: 942 EDEKRRRK---------EEEERRMKLEMEAKRKQEEEER---KKREDDEKRIQAEVEAQL 989
D K++ + EE ++R + E+E +Q EE+ K E + R+Q E++ +
Sbjct: 1374 SDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLV 1433
Query: 990 ARQKEEESQQQAVLEQERRDRELALRIAQSE--AELISDEAQADLALRRNDGTRPKMTPE 1047
+ ++Q+Q V E++ R+ +A+ + + +DE A R T+
Sbjct: 1434 V---DLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLAR 1490
Query: 1048 QM--AKEMSEFLSRGPAVL--------ATKAAAGTKKYDLSKWKYA-------------E 1084
+ A E E L R +L ++K G ++L K K A E
Sbjct: 1491 ALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEE 1550
Query: 1085 LRDTINTSCDIEL-----LAACREEFHRRLKVYHAWKSKNKKRNTETEQRAPKSVTDYD 1138
L D + + D +L + A + +F R L+ ++N E ++ + + +Y+
Sbjct: 1551 LEDELQATEDAKLRLEVNMQALKGQFERDLQA-------RDEQNEEKRRQLQRQLHEYE 1602
Score = 46.2 bits (108), Expect = 2e-04
Identities = 39/173 (22%), Positives = 85/173 (49%), Gaps = 11/173 (6%)
Query: 863 GKPEMNKQIKNLEISIDTLMAKIKSTMMTQEQIQKEYDALVKSSEELLSALQKKKQQEEE 922
G+ E KQ++ L+ + +++ ++++I K ++ L + L + ++
Sbjct: 1639 GREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAA 1698
Query: 923 AERLRRIQEEMEKERKRREEDEK---RRRKEEEERRMKLEMEAKRKQEEEERKKREDDEK 979
AER R+ Q ++EKE E R ++E+RR++ + ++ EEE+ E
Sbjct: 1699 AERARK-QADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSD 1757
Query: 980 RI-----QAE-VEAQLARQKEEESQQQAVLEQ-ERRDRELALRIAQSEAELIS 1025
R+ QAE + +LA ++ + ++ +Q ER+++EL ++ + E + S
Sbjct: 1758 RVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKS 1810
Score = 45.8 bits (107), Expect = 3e-04
Identities = 40/201 (19%), Positives = 94/201 (46%), Gaps = 26/201 (12%)
Query: 842 KVGTLKKRLDKFNEVVSVLKDGKPEMNKQIKNLEISIDTLMAKIKSTMMTQEQIQK---- 897
++ L++ L++ + + D + +Q + L + T + + ++Q+++
Sbjct: 1737 RIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKE 1796
Query: 898 ------EYDALVKSS-EELLSALQKKKQQEEEAERLRRIQEEMEKE-RKRREEDEKRRRK 949
E + VKS + ++AL+ K Q ++E++E+E R+++ + ++K
Sbjct: 1797 LRSKLHEMEGAVKSKFKSTIAALEAKIAQ---------LEEQVEQEAREKQAATKSLKQK 1847
Query: 950 EEEERRMKLEMEAKRKQEEEERKKREDDEKRIQAEVEAQLARQKEEESQQQAVLEQERRD 1009
+++ + + L++E +RK E+ +++ E R++ QL RQ EE ++ + RR
Sbjct: 1848 DKKLKEILLQVEDERKMAEQYKEQAEKGNARVK-----QLKRQLEEAEEESQRINANRRK 1902
Query: 1010 RELALRIAQSEAELISDEAQA 1030
+ L A E + E A
Sbjct: 1903 LQRELDEATESNEAMGREVNA 1923
Score = 45.1 bits (105), Expect = 4e-04
Identities = 47/225 (20%), Positives = 108/225 (48%), Gaps = 30/225 (13%)
Query: 838 DGLVKVGTLKKRLDKFNEVVSVLKDGKPEMNKQIKNLEISIDTLMAKIKSTM---MTQEQ 894
+ L K+ L+ + E + + + + KQ ++L ++ L +++ T+ TQ++
Sbjct: 1108 NALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQE 1167
Query: 895 I----QKEYDALVKSSEELLSA--LQKKKQQEEEAERLRRIQEEMEKERKRREEDEKRRR 948
+ ++E L K+ +E + Q ++ +++ A+ + + E++E+ ++ + +K ++
Sbjct: 1168 LRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQ 1227
Query: 949 ---KEEEERRMKLEMEAKRKQEEEERKKRED-----------DEKRIQAEVEAQLAR-QK 993
KE + +L + + KQE E +KK+ + D +R +AE+ ++ + Q
Sbjct: 1228 TLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQN 1287
Query: 994 EEESQQQAVLEQERRDRELALRIA------QSEAELISDEAQADL 1032
E ES + E E + +LA +A Q EL+ +E + L
Sbjct: 1288 EVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKL 1332
Score = 45.1 bits (105), Expect = 4e-04
Identities = 46/192 (23%), Positives = 87/192 (45%), Gaps = 43/192 (22%)
Query: 893 EQIQKEYDALVKSSEELLSALQKKKQQEEEAERLRRIQEEMEKERKRREE------DEKR 946
+ ++ + D+ +K EE + L+K + Q ++ Q E+E R R+E + ++
Sbjct: 1627 KDLELQADSAIKGREEAIKQLRKLQAQ------MKDFQRELEDARASRDEIFATAKENEK 1680
Query: 947 RRKEEEERRMKLE-----MEAKRKQ---EEEE-----------RKKREDDEKRIQAEVEA 987
+ K E M+L+ E RKQ E+EE R +D+++R++A + A
Sbjct: 1681 KAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARI-A 1739
Query: 988 QLARQKEEESQQQAVLEQERRDRELALRIAQSEAELISDEAQADLALRRNDGTRPKMTPE 1047
QL + EEE + +R A +AE +S+E LA R+ + + +
Sbjct: 1740 QLEEELEEEQGNMEAMSDR-------VRKATQQAEQLSNE----LATERSTAQKNESARQ 1788
Query: 1048 QMAKEMSEFLSR 1059
Q+ ++ E S+
Sbjct: 1789 QLERQNKELRSK 1800
Score = 38.9 bits (89), Expect = 0.032
Identities = 61/324 (18%), Positives = 135/324 (41%), Gaps = 65/324 (20%)
Query: 845 TLKKRLDKFNEVVSVLKDGKPEMNKQIKNLEISIDTLMAKIKSTMMTQEQIQKEYDALVK 904
T + ++ K + + V+ D +++K+ K LE I L + +E+ K L
Sbjct: 975 TAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAE----EEEKAKNLTKLKN 1030
Query: 905 SSEELLSALQKKKQQEE----EAERLRRIQE------------------EMEKERKRREE 942
E ++S L+ + ++EE E E+L+R E E++ + ++EE
Sbjct: 1031 KHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEE 1090
Query: 943 ----------DEKRRRKEEEERRMKLEMEAKRKQEEEE-----RKKREDDEKRIQAEVEA 987
DE ++ ++ +LE QE+ + R K E ++ + E+EA
Sbjct: 1091 ELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEA 1150
Query: 988 QLARQKEEESQQQAVLEQE---RRDRELALRIAQSEAELISDEAQADLALRRNDGTRPKM 1044
+ + E++ +QE +R++E+ + + E S EAQ +++
Sbjct: 1151 --LKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKH-----AQ 1203
Query: 1045 TPEQMAKEMSEFLSRGPAVLATKAAAGTKKYDLSKWKYAELRDTINTSCDIELLAACREE 1104
E++ +++ +F K A K +L K K ++ + + ++ +L ++E
Sbjct: 1204 AVEELTEQLEQF----------KRA----KANLDKNKQTLEKENADLAGELRVLGQAKQE 1249
Query: 1105 FHRRLKVYHAWKSKNKKRNTETEQ 1128
+ K A + + + ++ E+
Sbjct: 1250 VEHKKKKLEAQVQELQSKCSDGER 1273
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 478 bits (1231), Expect = e-134
Identities = 375/1207 (31%), Positives = 589/1207 (48%), Gaps = 170/1207 (14%)
Query: 7 VWAPHPTDGFQMGNIVDIGPDSLTIEPLNQKGKTFLALINQVFPAEEDSKKDVEDNCSLM 66
VW P GF+ +I + D + +E L + GK + + VED L
Sbjct: 36 VWVPSEKQGFEAASIKEEKGDEVVVE-LVENGKKVTVGKDDIQKMNPPKFSKVEDMAELT 94
Query: 67 YLNEATLLHNIKVRYSKDRIYTYVANILIAVNPYFDIPKIYSSEAIKSYQGKSLGTRPPH 126
LNEA++LHN++ RY IYTY + VNPY +P IYS + + Y+GK PPH
Sbjct: 95 CLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLP-IYSEKIVDMYKGKKRHEMPPH 153
Query: 127 VFAIADKAFRDMKVLKMSQSIIVSGESGAGKTENTKFVLRYLT----------------- 169
++AIAD A+R M + QSI+ +GESGAGKTENTK V++YL
Sbjct: 154 IYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKDTSITQG 213
Query: 170 ESYGTGQDIDDRIVEANPLLEAFGNAKTVRNNNSSRFGKFVEIHFNEKSSVVGGFVSHYL 229
S+ G+ ++ ++++ANP+LEAFGNAKTV+N+NSSRFGKF+ I+F+ +VG + YL
Sbjct: 214 PSFAYGE-LEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYL 272
Query: 230 LEKSRICVQGKEERNYHIFYRLCAGASEDIREKLHLSSPDNFRYLNRGCTRYFANKETDK 289
LEKSR Q ++ER +HIFY + AGA E +R L L +N+ +L+ G
Sbjct: 273 LEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLSNGFVPI-------- 324
Query: 290 QILQNRKSPEYLKAGSMKDPLLDDHGDFIRMCTAMKKIGLDDEEKLDLFRVVAGVLHLGN 349
P D F AM +G +EE+L + +VV+ VL LGN
Sbjct: 325 -------------------PAAQDDEMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGN 365
Query: 350 IDFEEAGSTSGGCNLKNKSAQSLEYCAELLGLDQDDLRVSLTTRVMLTTAGGTKGTVIKV 409
I F++ +T N +AQ + L+G++ D TR +LT V++
Sbjct: 366 IVFKKERNTDQASMPDNTAAQKV---CHLMGINVTDF-----TRSILTPRIKVGRDVVQK 417
Query: 410 PLKVEQANNARDALAKTVYSHLFDHVVNRVNQCFP--FETSSYFIGVLDIAGFEYFEHNS 467
EQA+ A +ALAK Y LF ++ RVN+ + F+G+LDIAGFE FE NS
Sbjct: 418 AQTKEQADFAVEALAKATYERLFRWILTRVNKALDKTHRQGASFLGILDIAGFEIFEVNS 477
Query: 468 FEQFCINYCNEKLQQFFNERILKEEQELYQKEGLGVNEVHY-VDNQDCIDLIEA--KLVG 524
FEQ CINY NEKLQQ FN + EQE YQ+EG+ N + + +D Q CI+LIE G
Sbjct: 478 FEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIELIERPNNPPG 537
Query: 525 ILDILDEENRLPQPSDQHFTSAVHQKHKDHFRLTIPRKSKLAVHRNIRDDEGFIIRHFAG 584
+L +LDEE P+ +D+ F + + H + P++ ++D F I H+AG
Sbjct: 538 VLALLDEECWFPKATDKSFVEKLCTEQGSHPKFQKPKQ--------LKDKTEFSIIHYAG 589
Query: 585 AVCYETTQFVEKNNDALHMSLESLICESRDKFIRELFE------------SSTNNNKDTK 632
V Y + ++ KN D L+ ++ SL+ S DKF+ +L++ T ++ +
Sbjct: 590 KVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWKDVDRIVGLDQMAKMTESSLPSA 649
Query: 633 QKAGKLSFISVGNKFKTQLNLLLDKLRSTGASFIRCIKPNLKMTSHHFEGAQILSQLQCS 692
K K F +VG +K QL L+ LR+T +F+RCI PN + S + +L QL+C+
Sbjct: 650 SKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNHEKRSGKLDAFLVLEQLRCN 709
Query: 693 GMVSVLDLMQGGYPSRASFHELYNMYKKYMPDKLAR--LDPRLFCKALFKALGLNENDYK 750
G++ + + + G+P+R F E Y+ + + + +D + C + KAL L+ N Y+
Sbjct: 710 GVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKGFMDGKQACILMIKALELDPNLYR 769
Query: 751 FGLTKVFFRPGKFAEFDQIMK-SDPDHLAELVKRVNHWLTCSRWKKVQWCSLSVIKLKNK 809
G +K+FFR G A ++ D + +L + K Q L+ +K+
Sbjct: 770 IGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQ-QLTAMKV--- 825
Query: 810 IKYRAEACIKMQKTIRMWLCKRRHKPRIDGLVKVGTLKKRLDKFNEVVSVLKDGKPEMNK 869
I+ A +K+ + + W + KP L++V ++ + + + K+ + +
Sbjct: 826 IQRNCAAYLKL-RNWQWWRLFTKVKP----LLQVTRQEEEMQAKEDELQKTKERQQKAEN 880
Query: 870 QIKNLEISIDTLMAKIKSTMMTQEQIQKEYDALVKSSEELLSALQKKKQQEEEA--ERLR 927
++K LE L + + QEQ+Q E + L +EE+ L KKQ+ EE E
Sbjct: 881 ELKELEQKHSQL---TEEKNLLQEQLQAETE-LYAEAEEMRVRLAAKKQELEEILHEMEA 936
Query: 928 RIQEE------MEKERKRREE---DEKRRRKEEEERRMKLEM-----EAKRKQEEEERKK 973
R++EE ++ ERK+ + D + + +EEE R KL++ EAK K+ E+E
Sbjct: 937 RLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILV 996
Query: 974 REDDEKRIQAE------------------------------------VEAQLARQKEEES 997
+D ++ E E ++ +KEE+S
Sbjct: 997 MDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKS 1056
Query: 998 QQQAVLEQERRDRE------------LALRIAQSEAELISDEAQADLALRR-NDGTRPKM 1044
+Q+ LE+ +R E L +IA+ + +L E + AL R +D K
Sbjct: 1057 RQE--LEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKN 1114
Query: 1045 TPEQMAKEMSEFLSRGPAVLATKAAAGTK----KYDLSKWKYA---ELRDTINTSCDIEL 1097
+ +E+ +S L ++ AA K K DL + A EL DT++++ +
Sbjct: 1115 NALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQE 1174
Query: 1098 LAACREE 1104
L A RE+
Sbjct: 1175 LRAKREQ 1181
Score = 67.8 bits (164), Expect = 6e-11
Identities = 47/193 (24%), Positives = 94/193 (48%), Gaps = 9/193 (4%)
Query: 841 VKVGTLKKRLDKFNEVVSVLKDGKPEMNKQIKNLEISIDTLMAKIKSTMMTQEQIQKEYD 900
+++ KK+L F V L++GK K+I+NL + A T+ ++Q+E D
Sbjct: 1378 IQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELD 1437
Query: 901 ALV---KSSEELLSALQKKKQQEEEAERLRRIQEEMEKERKRREEDEKRRRKEEEERRMK 957
LV + +L+S L+KK+++ ++ + EE K +E ++ + E+
Sbjct: 1438 DLVVDLDNQRQLVSNLEKKQRKFDQL-----LAEEKNISSKYADERDRAEAEAREKETKA 1492
Query: 958 LEMEAKRKQEEEERKKREDDEKRIQAEVEAQLARQKEEESQQQAVLEQERRDRELALRIA 1017
L + ++ E +++ E K ++AE+E L K++ + LE+ +R E +
Sbjct: 1493 LSLARALEEALEAKEELERTNKMLKAEME-DLVSSKDDVGKNVHELEKSKRALETQMEEM 1551
Query: 1018 QSEAELISDEAQA 1030
+++ E + DE QA
Sbjct: 1552 KTQLEELEDELQA 1564
Score = 59.7 bits (143), Expect = 2e-08
Identities = 59/246 (23%), Positives = 112/246 (45%), Gaps = 27/246 (10%)
Query: 806 LKNKIKYRAEACIKMQKTIRMWLCKRRHKPRIDGLVK--------VGTLKKRLDKFNEVV 857
L + + +A A K++KT K R + +D LV V L+K+ KF++++
Sbjct: 1411 LTQQYEEKAAAYDKLEKT------KNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLL 1464
Query: 858 SVLK-------DGKPEMNKQIKNLEISIDTLMAKIKSTMMTQEQIQKEYDALVKSSEELL 910
+ K D + + + E +L ++ + +E++++ L E+L+
Sbjct: 1465 AEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLV 1524
Query: 911 SALQKKKQQEEEAERLRRIQEEMEKERKRREEDEKRRRKEEEERRMKLEMEAKRKQEEEE 970
S+ + E E+ +R E +E K + E+ + + E+ +++LE+ + + + E
Sbjct: 1525 SSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFE 1584
Query: 971 RKKREDDEKRIQAEVEAQLARQKEEESQQQAVLEQERRDRELALRIAQS-EAELISDEAQ 1029
R + DE+ E QL RQ E + LE ER+ R LA + E +L E Q
Sbjct: 1585 RDLQARDEQ--NEEKRRQLQRQLHE---YETELEDERKQRALAAAAKKKLEGDLKDLELQ 1639
Query: 1030 ADLALR 1035
AD A++
Sbjct: 1640 ADSAIK 1645
Score = 54.7 bits (130), Expect = 6e-07
Identities = 53/226 (23%), Positives = 99/226 (43%), Gaps = 16/226 (7%)
Query: 847 KKRLDKFNEVVSV----LKDGKPEMNKQIKNLEISIDTLMAKIKSTMMTQEQIQKEYDAL 902
K+ L++ N+++ L K ++ K + LE S L +++ E+++ E A
Sbjct: 1506 KEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQAT 1565
Query: 903 VKSSEELLSALQKKKQQEEEAERLRRIQEEMEKERKRREEDEKRRRKEEEERRMKLEMEA 962
+ L +Q K Q E + R Q E ++ + +R+ E E+E ++ L A
Sbjct: 1566 EDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAA 1625
Query: 963 KRKQEEEERKKREDDEKRIQAEVEA--QLARQKEEESQQQAVLEQERRDRELALRIAQS- 1019
K+K E + + + I+ EA QL + + + Q LE R R+ A+
Sbjct: 1626 KKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKEN 1685
Query: 1020 -------EAELISDEAQADLALRRNDGTRPKMTPEQMAKEMSEFLS 1058
EA+L+ + Q DLA + + E++A+E++ LS
Sbjct: 1686 EKKAKSLEADLM--QLQEDLAAAERARKQADLEKEELAEELASSLS 1729
Score = 51.6 bits (122), Expect = 5e-06
Identities = 52/205 (25%), Positives = 95/205 (46%), Gaps = 24/205 (11%)
Query: 821 QKTIRMWLCKRRHKPRIDGL-VKVGTLKKRLDKFNEVVSVLKDGKPEMNKQIKNLEISID 879
+K + K +H+ I L V++ +K + ++ L+ + ++QI +L+ I
Sbjct: 1027 EKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIA 1086
Query: 880 TLMAKIKSTMMTQEQIQKEYDALVKSSEELLSALQKKKQQEEEAERLRRIQEEMEKERKR 939
L ++ +E++Q AL + +E+ K+ E + +QE+++ ER
Sbjct: 1087 ELKMQLAKK---EEELQA---ALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAA 1140
Query: 940 REEDEKRRRKEEEE-RRMKLEME-------------AKRKQEEEERKKREDDEKRIQAEV 985
R + EK++R EE +K E+E AKR+QE KK D+E R E
Sbjct: 1141 RNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSH-EA 1199
Query: 986 EAQLARQKEEESQQQAV--LEQERR 1008
+ Q RQK ++ ++ LEQ +R
Sbjct: 1200 QVQEMRQKHAQAVEELTEQLEQFKR 1224
Score = 49.3 bits (116), Expect = 2e-05
Identities = 50/216 (23%), Positives = 100/216 (46%), Gaps = 34/216 (15%)
Query: 866 EMNKQIKNLEISIDTLMAKIKSTMMTQEQIQKEYDALVKSSEELLSALQKKKQQEEEAER 925
E K+ K+LE + L + + ++Q E + L +EEL S+L + ++E R
Sbjct: 1684 ENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEEL---AEELASSLSGRNALQDEKRR 1740
Query: 926 LR----RIQEEMEKERKRREEDEKRRRKEEE-----------ERRMKLEMEAKRKQEE-- 968
L +++EE+E+E+ E R RK + ER + E+ R+Q E
Sbjct: 1741 LEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQ 1800
Query: 969 --EERKKREDDEKRIQAEVEAQLARQKEEESQQQAVLEQERRDRELALRIAQSEAELISD 1026
E R K + E ++++ ++ +A + + +Q + +EQE R+++ A + + + D
Sbjct: 1801 NKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQK-----D 1855
Query: 1027 EAQADLALRRNDGTRPKMTPEQMAKEMSEFLSRGPA 1062
+ ++ L+ D +MA++ E +G A
Sbjct: 1856 KKLKEILLQVED-------ERKMAEQYKEQAEKGNA 1884
Score = 46.6 bits (109), Expect = 2e-04
Identities = 75/359 (20%), Positives = 149/359 (41%), Gaps = 77/359 (21%)
Query: 847 KKRLD-KFNEVVSVLKDG---KPEMNKQIKNLEISIDTLMAKI-----------KSTMMT 891
KK+L+ + E+ S DG + E+N ++ L+ ++++ + K
Sbjct: 1261 KKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASL 1320
Query: 892 QEQIQKEYDALVKSSEELLSALQKKKQQEEEAERLR-RIQEEMEKERKRRE--------- 941
Q+Q + L + + + L+ K +Q EEE L+ ++ EEME ++
Sbjct: 1321 SSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQL 1380
Query: 942 EDEKRRRK---------EEEERRMKLEMEAKRKQEEEER---KKREDDEKRIQAEVEAQL 989
D K++ + EE ++R + E+E +Q EE+ K E + R+Q E++ +
Sbjct: 1381 SDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLV 1440
Query: 990 ARQKEEESQQQAVLEQERRDRELALRIAQSE--AELISDEAQADLALRRNDGTRPKMTPE 1047
+ ++Q+Q V E++ R+ +A+ + + +DE A R T+
Sbjct: 1441 V---DLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLAR 1497
Query: 1048 QM--AKEMSEFLSRGPAVL--------ATKAAAGTKKYDLSKWKYA-------------E 1084
+ A E E L R +L ++K G ++L K K A E
Sbjct: 1498 ALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEE 1557
Query: 1085 LRDTINTSCDIEL-----LAACREEFHRRLKVYHAWKSKNKKRNTETEQRAPKSVTDYD 1138
L D + + D +L + A + +F R L+ ++N E ++ + + +Y+
Sbjct: 1558 LEDELQATEDAKLRLEVNMQALKGQFERDLQA-------RDEQNEEKRRQLQRQLHEYE 1609
Score = 46.6 bits (109), Expect = 2e-04
Identities = 44/212 (20%), Positives = 99/212 (46%), Gaps = 27/212 (12%)
Query: 842 KVGTLKKRLDKFNEVVSVLKDGKPEMNKQIKNLEISIDTLMAKIKSTMMTQEQIQK---- 897
++ L++ L++ + + D + +Q + L + T + + ++Q+++
Sbjct: 1744 RIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKE 1803
Query: 898 ------EYDALVKSS-EELLSALQKKKQQEEEAERLRRIQEEMEKE-RKRREEDEKRRRK 949
E + VKS + ++AL+ K Q ++E++E+E R+++ + ++K
Sbjct: 1804 LRSKLHEMEGAVKSKFKSTIAALEAKIAQ---------LEEQVEQEAREKQAATKSLKQK 1854
Query: 950 EEEERRMKLEMEAKRKQEEEERKKREDDEKRIQAEVEAQLARQKEEESQQQAVLEQERRD 1009
+++ + + L++E +RK E+ +++ E R++ QL RQ EE ++ + RR
Sbjct: 1855 DKKLKEILLQVEDERKMAEQYKEQAEKGNARVK-----QLKRQLEEAEEESQRINANRRK 1909
Query: 1010 RELALRIAQSEAELISDEAQA-DLALRRNDGT 1040
+ L A E + E A LRR + T
Sbjct: 1910 LQRELDEATESNEAMGREVNALKSKLRRGNET 1941
Score = 46.2 bits (108), Expect = 2e-04
Identities = 39/173 (22%), Positives = 85/173 (49%), Gaps = 11/173 (6%)
Query: 863 GKPEMNKQIKNLEISIDTLMAKIKSTMMTQEQIQKEYDALVKSSEELLSALQKKKQQEEE 922
G+ E KQ++ L+ + +++ ++++I K ++ L + L + ++
Sbjct: 1646 GREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAA 1705
Query: 923 AERLRRIQEEMEKERKRREEDEK---RRRKEEEERRMKLEMEAKRKQEEEERKKREDDEK 979
AER R+ Q ++EKE E R ++E+RR++ + ++ EEE+ E
Sbjct: 1706 AERARK-QADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSD 1764
Query: 980 RI-----QAE-VEAQLARQKEEESQQQAVLEQ-ERRDRELALRIAQSEAELIS 1025
R+ QAE + +LA ++ + ++ +Q ER+++EL ++ + E + S
Sbjct: 1765 RVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKS 1817
Score = 45.1 bits (105), Expect = 4e-04
Identities = 47/225 (20%), Positives = 108/225 (48%), Gaps = 30/225 (13%)
Query: 838 DGLVKVGTLKKRLDKFNEVVSVLKDGKPEMNKQIKNLEISIDTLMAKIKSTM---MTQEQ 894
+ L K+ L+ + E + + + + KQ ++L ++ L +++ T+ TQ++
Sbjct: 1115 NALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQE 1174
Query: 895 I----QKEYDALVKSSEELLSA--LQKKKQQEEEAERLRRIQEEMEKERKRREEDEKRRR 948
+ ++E L K+ +E + Q ++ +++ A+ + + E++E+ ++ + +K ++
Sbjct: 1175 LRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQ 1234
Query: 949 ---KEEEERRMKLEMEAKRKQEEEERKKRED-----------DEKRIQAEVEAQLAR-QK 993
KE + +L + + KQE E +KK+ + D +R +AE+ ++ + Q
Sbjct: 1235 TLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQN 1294
Query: 994 EEESQQQAVLEQERRDRELALRIA------QSEAELISDEAQADL 1032
E ES + E E + +LA +A Q EL+ +E + L
Sbjct: 1295 EVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKL 1339
Score = 45.1 bits (105), Expect = 4e-04
Identities = 46/192 (23%), Positives = 87/192 (45%), Gaps = 43/192 (22%)
Query: 893 EQIQKEYDALVKSSEELLSALQKKKQQEEEAERLRRIQEEMEKERKRREE------DEKR 946
+ ++ + D+ +K EE + L+K + Q ++ Q E+E R R+E + ++
Sbjct: 1634 KDLELQADSAIKGREEAIKQLRKLQAQ------MKDFQRELEDARASRDEIFATAKENEK 1687
Query: 947 RRKEEEERRMKLE-----MEAKRKQ---EEEE-----------RKKREDDEKRIQAEVEA 987
+ K E M+L+ E RKQ E+EE R +D+++R++A + A
Sbjct: 1688 KAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARI-A 1746
Query: 988 QLARQKEEESQQQAVLEQERRDRELALRIAQSEAELISDEAQADLALRRNDGTRPKMTPE 1047
QL + EEE + +R A +AE +S+E LA R+ + + +
Sbjct: 1747 QLEEELEEEQGNMEAMSDR-------VRKATQQAEQLSNE----LATERSTAQKNESARQ 1795
Query: 1048 QMAKEMSEFLSR 1059
Q+ ++ E S+
Sbjct: 1796 QLERQNKELRSK 1807
Score = 38.9 bits (89), Expect = 0.032
Identities = 61/324 (18%), Positives = 135/324 (41%), Gaps = 65/324 (20%)
Query: 845 TLKKRLDKFNEVVSVLKDGKPEMNKQIKNLEISIDTLMAKIKSTMMTQEQIQKEYDALVK 904
T + ++ K + + V+ D +++K+ K LE I L + +E+ K L
Sbjct: 982 TAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAE----EEEKAKNLTKLKN 1037
Query: 905 SSEELLSALQKKKQQEE----EAERLRRIQE------------------EMEKERKRREE 942
E ++S L+ + ++EE E E+L+R E E++ + ++EE
Sbjct: 1038 KHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEE 1097
Query: 943 ----------DEKRRRKEEEERRMKLEMEAKRKQEEEE-----RKKREDDEKRIQAEVEA 987
DE ++ ++ +LE QE+ + R K E ++ + E+EA
Sbjct: 1098 ELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEA 1157
Query: 988 QLARQKEEESQQQAVLEQE---RRDRELALRIAQSEAELISDEAQADLALRRNDGTRPKM 1044
+ + E++ +QE +R++E+ + + E S EAQ +++
Sbjct: 1158 --LKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKH-----AQ 1210
Query: 1045 TPEQMAKEMSEFLSRGPAVLATKAAAGTKKYDLSKWKYAELRDTINTSCDIELLAACREE 1104
E++ +++ +F K A K +L K K ++ + + ++ +L ++E
Sbjct: 1211 AVEELTEQLEQF----------KRA----KANLDKNKQTLEKENADLAGELRVLGQAKQE 1256
Query: 1105 FHRRLKVYHAWKSKNKKRNTETEQ 1128
+ K A + + + ++ E+
Sbjct: 1257 VEHKKKKLEAQVQELQSKCSDGER 1280
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 478 bits (1231), Expect = e-134
Identities = 375/1207 (31%), Positives = 589/1207 (48%), Gaps = 170/1207 (14%)
Query: 7 VWAPHPTDGFQMGNIVDIGPDSLTIEPLNQKGKTFLALINQVFPAEEDSKKDVEDNCSLM 66
VW P GF+ +I + D + +E L + GK + + VED L
Sbjct: 36 VWVPSEKQGFEAASIKEEKGDEVVVE-LVENGKKVTVGKDDIQKMNPPKFSKVEDMAELT 94
Query: 67 YLNEATLLHNIKVRYSKDRIYTYVANILIAVNPYFDIPKIYSSEAIKSYQGKSLGTRPPH 126
LNEA++LHN++ RY IYTY + VNPY +P IYS + + Y+GK PPH
Sbjct: 95 CLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLP-IYSEKIVDMYKGKKRHEMPPH 153
Query: 127 VFAIADKAFRDMKVLKMSQSIIVSGESGAGKTENTKFVLRYLT----------------- 169
++AIAD A+R M + QSI+ +GESGAGKTENTK V++YL
Sbjct: 154 IYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKDTSITQG 213
Query: 170 ESYGTGQDIDDRIVEANPLLEAFGNAKTVRNNNSSRFGKFVEIHFNEKSSVVGGFVSHYL 229
S+ G+ ++ ++++ANP+LEAFGNAKTV+N+NSSRFGKF+ I+F+ +VG + YL
Sbjct: 214 PSFAYGE-LEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYL 272
Query: 230 LEKSRICVQGKEERNYHIFYRLCAGASEDIREKLHLSSPDNFRYLNRGCTRYFANKETDK 289
LEKSR Q ++ER +HIFY + AGA E +R L L +N+ +L+ G
Sbjct: 273 LEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLSNGFVPI-------- 324
Query: 290 QILQNRKSPEYLKAGSMKDPLLDDHGDFIRMCTAMKKIGLDDEEKLDLFRVVAGVLHLGN 349
P D F AM +G +EE+L + +VV+ VL LGN
Sbjct: 325 -------------------PAAQDDEMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGN 365
Query: 350 IDFEEAGSTSGGCNLKNKSAQSLEYCAELLGLDQDDLRVSLTTRVMLTTAGGTKGTVIKV 409
I F++ +T N +AQ + L+G++ D TR +LT V++
Sbjct: 366 IVFKKERNTDQASMPDNTAAQKV---CHLMGINVTDF-----TRSILTPRIKVGRDVVQK 417
Query: 410 PLKVEQANNARDALAKTVYSHLFDHVVNRVNQCFP--FETSSYFIGVLDIAGFEYFEHNS 467
EQA+ A +ALAK Y LF ++ RVN+ + F+G+LDIAGFE FE NS
Sbjct: 418 AQTKEQADFAVEALAKATYERLFRWILTRVNKALDKTHRQGASFLGILDIAGFEIFEVNS 477
Query: 468 FEQFCINYCNEKLQQFFNERILKEEQELYQKEGLGVNEVHY-VDNQDCIDLIEA--KLVG 524
FEQ CINY NEKLQQ FN + EQE YQ+EG+ N + + +D Q CI+LIE G
Sbjct: 478 FEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIELIERPNNPPG 537
Query: 525 ILDILDEENRLPQPSDQHFTSAVHQKHKDHFRLTIPRKSKLAVHRNIRDDEGFIIRHFAG 584
+L +LDEE P+ +D+ F + + H + P++ ++D F I H+AG
Sbjct: 538 VLALLDEECWFPKATDKSFVEKLCTEQGSHPKFQKPKQ--------LKDKTEFSIIHYAG 589
Query: 585 AVCYETTQFVEKNNDALHMSLESLICESRDKFIRELFE------------SSTNNNKDTK 632
V Y + ++ KN D L+ ++ SL+ S DKF+ +L++ T ++ +
Sbjct: 590 KVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWKDVDRIVGLDQMAKMTESSLPSA 649
Query: 633 QKAGKLSFISVGNKFKTQLNLLLDKLRSTGASFIRCIKPNLKMTSHHFEGAQILSQLQCS 692
K K F +VG +K QL L+ LR+T +F+RCI PN + S + +L QL+C+
Sbjct: 650 SKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNHEKRSGKLDAFLVLEQLRCN 709
Query: 693 GMVSVLDLMQGGYPSRASFHELYNMYKKYMPDKLAR--LDPRLFCKALFKALGLNENDYK 750
G++ + + + G+P+R F E Y+ + + + +D + C + KAL L+ N Y+
Sbjct: 710 GVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKGFMDGKQACILMIKALELDPNLYR 769
Query: 751 FGLTKVFFRPGKFAEFDQIMK-SDPDHLAELVKRVNHWLTCSRWKKVQWCSLSVIKLKNK 809
G +K+FFR G A ++ D + +L + K Q L+ +K+
Sbjct: 770 IGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQ-QLTAMKV--- 825
Query: 810 IKYRAEACIKMQKTIRMWLCKRRHKPRIDGLVKVGTLKKRLDKFNEVVSVLKDGKPEMNK 869
I+ A +K+ + + W + KP L++V ++ + + + K+ + +
Sbjct: 826 IQRNCAAYLKL-RNWQWWRLFTKVKP----LLQVTRQEEEMQAKEDELQKTKERQQKAEN 880
Query: 870 QIKNLEISIDTLMAKIKSTMMTQEQIQKEYDALVKSSEELLSALQKKKQQEEEA--ERLR 927
++K LE L + + QEQ+Q E + L +EE+ L KKQ+ EE E
Sbjct: 881 ELKELEQKHSQL---TEEKNLLQEQLQAETE-LYAEAEEMRVRLAAKKQELEEILHEMEA 936
Query: 928 RIQEE------MEKERKRREE---DEKRRRKEEEERRMKLEM-----EAKRKQEEEERKK 973
R++EE ++ ERK+ + D + + +EEE R KL++ EAK K+ E+E
Sbjct: 937 RLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILV 996
Query: 974 REDDEKRIQAE------------------------------------VEAQLARQKEEES 997
+D ++ E E ++ +KEE+S
Sbjct: 997 MDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKS 1056
Query: 998 QQQAVLEQERRDRE------------LALRIAQSEAELISDEAQADLALRR-NDGTRPKM 1044
+Q+ LE+ +R E L +IA+ + +L E + AL R +D K
Sbjct: 1057 RQE--LEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKN 1114
Query: 1045 TPEQMAKEMSEFLSRGPAVLATKAAAGTK----KYDLSKWKYA---ELRDTINTSCDIEL 1097
+ +E+ +S L ++ AA K K DL + A EL DT++++ +
Sbjct: 1115 NALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQE 1174
Query: 1098 LAACREE 1104
L A RE+
Sbjct: 1175 LRAKREQ 1181
Score = 67.8 bits (164), Expect = 6e-11
Identities = 47/193 (24%), Positives = 94/193 (48%), Gaps = 9/193 (4%)
Query: 841 VKVGTLKKRLDKFNEVVSVLKDGKPEMNKQIKNLEISIDTLMAKIKSTMMTQEQIQKEYD 900
+++ KK+L F V L++GK K+I+NL + A T+ ++Q+E D
Sbjct: 1378 IQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELD 1437
Query: 901 ALV---KSSEELLSALQKKKQQEEEAERLRRIQEEMEKERKRREEDEKRRRKEEEERRMK 957
LV + +L+S L+KK+++ ++ + EE K +E ++ + E+
Sbjct: 1438 DLVVDLDNQRQLVSNLEKKQRKFDQL-----LAEEKNISSKYADERDRAEAEAREKETKA 1492
Query: 958 LEMEAKRKQEEEERKKREDDEKRIQAEVEAQLARQKEEESQQQAVLEQERRDRELALRIA 1017
L + ++ E +++ E K ++AE+E L K++ + LE+ +R E +
Sbjct: 1493 LSLARALEEALEAKEELERTNKMLKAEME-DLVSSKDDVGKNVHELEKSKRALETQMEEM 1551
Query: 1018 QSEAELISDEAQA 1030
+++ E + DE QA
Sbjct: 1552 KTQLEELEDELQA 1564
Score = 59.7 bits (143), Expect = 2e-08
Identities = 59/246 (23%), Positives = 112/246 (45%), Gaps = 27/246 (10%)
Query: 806 LKNKIKYRAEACIKMQKTIRMWLCKRRHKPRIDGLVK--------VGTLKKRLDKFNEVV 857
L + + +A A K++KT K R + +D LV V L+K+ KF++++
Sbjct: 1411 LTQQYEEKAAAYDKLEKT------KNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLL 1464
Query: 858 SVLK-------DGKPEMNKQIKNLEISIDTLMAKIKSTMMTQEQIQKEYDALVKSSEELL 910
+ K D + + + E +L ++ + +E++++ L E+L+
Sbjct: 1465 AEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLV 1524
Query: 911 SALQKKKQQEEEAERLRRIQEEMEKERKRREEDEKRRRKEEEERRMKLEMEAKRKQEEEE 970
S+ + E E+ +R E +E K + E+ + + E+ +++LE+ + + + E
Sbjct: 1525 SSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFE 1584
Query: 971 RKKREDDEKRIQAEVEAQLARQKEEESQQQAVLEQERRDRELALRIAQS-EAELISDEAQ 1029
R + DE+ E QL RQ E + LE ER+ R LA + E +L E Q
Sbjct: 1585 RDLQARDEQ--NEEKRRQLQRQLHE---YETELEDERKQRALAAAAKKKLEGDLKDLELQ 1639
Query: 1030 ADLALR 1035
AD A++
Sbjct: 1640 ADSAIK 1645
Score = 54.7 bits (130), Expect = 6e-07
Identities = 53/226 (23%), Positives = 99/226 (43%), Gaps = 16/226 (7%)
Query: 847 KKRLDKFNEVVSV----LKDGKPEMNKQIKNLEISIDTLMAKIKSTMMTQEQIQKEYDAL 902
K+ L++ N+++ L K ++ K + LE S L +++ E+++ E A
Sbjct: 1506 KEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQAT 1565
Query: 903 VKSSEELLSALQKKKQQEEEAERLRRIQEEMEKERKRREEDEKRRRKEEEERRMKLEMEA 962
+ L +Q K Q E + R Q E ++ + +R+ E E+E ++ L A
Sbjct: 1566 EDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAA 1625
Query: 963 KRKQEEEERKKREDDEKRIQAEVEA--QLARQKEEESQQQAVLEQERRDRELALRIAQS- 1019
K+K E + + + I+ EA QL + + + Q LE R R+ A+
Sbjct: 1626 KKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKEN 1685
Query: 1020 -------EAELISDEAQADLALRRNDGTRPKMTPEQMAKEMSEFLS 1058
EA+L+ + Q DLA + + E++A+E++ LS
Sbjct: 1686 EKKAKSLEADLM--QLQEDLAAAERARKQADLEKEELAEELASSLS 1729
Score = 51.6 bits (122), Expect = 5e-06
Identities = 52/205 (25%), Positives = 95/205 (46%), Gaps = 24/205 (11%)
Query: 821 QKTIRMWLCKRRHKPRIDGL-VKVGTLKKRLDKFNEVVSVLKDGKPEMNKQIKNLEISID 879
+K + K +H+ I L V++ +K + ++ L+ + ++QI +L+ I
Sbjct: 1027 EKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIA 1086
Query: 880 TLMAKIKSTMMTQEQIQKEYDALVKSSEELLSALQKKKQQEEEAERLRRIQEEMEKERKR 939
L ++ +E++Q AL + +E+ K+ E + +QE+++ ER
Sbjct: 1087 ELKMQLAKK---EEELQA---ALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAA 1140
Query: 940 REEDEKRRRKEEEE-RRMKLEME-------------AKRKQEEEERKKREDDEKRIQAEV 985
R + EK++R EE +K E+E AKR+QE KK D+E R E
Sbjct: 1141 RNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSH-EA 1199
Query: 986 EAQLARQKEEESQQQAV--LEQERR 1008
+ Q RQK ++ ++ LEQ +R
Sbjct: 1200 QVQEMRQKHAQAVEELTEQLEQFKR 1224
Score = 49.3 bits (116), Expect = 2e-05
Identities = 50/216 (23%), Positives = 100/216 (46%), Gaps = 34/216 (15%)
Query: 866 EMNKQIKNLEISIDTLMAKIKSTMMTQEQIQKEYDALVKSSEELLSALQKKKQQEEEAER 925
E K+ K+LE + L + + ++Q E + L +EEL S+L + ++E R
Sbjct: 1684 ENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEEL---AEELASSLSGRNALQDEKRR 1740
Query: 926 LR----RIQEEMEKERKRREEDEKRRRKEEE-----------ERRMKLEMEAKRKQEE-- 968
L +++EE+E+E+ E R RK + ER + E+ R+Q E
Sbjct: 1741 LEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQ 1800
Query: 969 --EERKKREDDEKRIQAEVEAQLARQKEEESQQQAVLEQERRDRELALRIAQSEAELISD 1026
E R K + E ++++ ++ +A + + +Q + +EQE R+++ A + + + D
Sbjct: 1801 NKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQK-----D 1855
Query: 1027 EAQADLALRRNDGTRPKMTPEQMAKEMSEFLSRGPA 1062
+ ++ L+ D +MA++ E +G A
Sbjct: 1856 KKLKEILLQVED-------ERKMAEQYKEQAEKGNA 1884
Score = 46.6 bits (109), Expect = 2e-04
Identities = 75/359 (20%), Positives = 149/359 (41%), Gaps = 77/359 (21%)
Query: 847 KKRLD-KFNEVVSVLKDG---KPEMNKQIKNLEISIDTLMAKI-----------KSTMMT 891
KK+L+ + E+ S DG + E+N ++ L+ ++++ + K
Sbjct: 1261 KKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASL 1320
Query: 892 QEQIQKEYDALVKSSEELLSALQKKKQQEEEAERLR-RIQEEMEKERKRRE--------- 941
Q+Q + L + + + L+ K +Q EEE L+ ++ EEME ++
Sbjct: 1321 SSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQL 1380
Query: 942 EDEKRRRK---------EEEERRMKLEMEAKRKQEEEER---KKREDDEKRIQAEVEAQL 989
D K++ + EE ++R + E+E +Q EE+ K E + R+Q E++ +
Sbjct: 1381 SDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLV 1440
Query: 990 ARQKEEESQQQAVLEQERRDRELALRIAQSE--AELISDEAQADLALRRNDGTRPKMTPE 1047
+ ++Q+Q V E++ R+ +A+ + + +DE A R T+
Sbjct: 1441 V---DLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLAR 1497
Query: 1048 QM--AKEMSEFLSRGPAVL--------ATKAAAGTKKYDLSKWKYA-------------E 1084
+ A E E L R +L ++K G ++L K K A E
Sbjct: 1498 ALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEE 1557
Query: 1085 LRDTINTSCDIEL-----LAACREEFHRRLKVYHAWKSKNKKRNTETEQRAPKSVTDYD 1138
L D + + D +L + A + +F R L+ ++N E ++ + + +Y+
Sbjct: 1558 LEDELQATEDAKLRLEVNMQALKGQFERDLQA-------RDEQNEEKRRQLQRQLHEYE 1609
Score = 46.2 bits (108), Expect = 2e-04
Identities = 39/173 (22%), Positives = 85/173 (49%), Gaps = 11/173 (6%)
Query: 863 GKPEMNKQIKNLEISIDTLMAKIKSTMMTQEQIQKEYDALVKSSEELLSALQKKKQQEEE 922
G+ E KQ++ L+ + +++ ++++I K ++ L + L + ++
Sbjct: 1646 GREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAA 1705
Query: 923 AERLRRIQEEMEKERKRREEDEK---RRRKEEEERRMKLEMEAKRKQEEEERKKREDDEK 979
AER R+ Q ++EKE E R ++E+RR++ + ++ EEE+ E
Sbjct: 1706 AERARK-QADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSD 1764
Query: 980 RI-----QAE-VEAQLARQKEEESQQQAVLEQ-ERRDRELALRIAQSEAELIS 1025
R+ QAE + +LA ++ + ++ +Q ER+++EL ++ + E + S
Sbjct: 1765 RVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKS 1817
Score = 45.8 bits (107), Expect = 3e-04
Identities = 40/201 (19%), Positives = 94/201 (46%), Gaps = 26/201 (12%)
Query: 842 KVGTLKKRLDKFNEVVSVLKDGKPEMNKQIKNLEISIDTLMAKIKSTMMTQEQIQK---- 897
++ L++ L++ + + D + +Q + L + T + + ++Q+++
Sbjct: 1744 RIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKE 1803
Query: 898 ------EYDALVKSS-EELLSALQKKKQQEEEAERLRRIQEEMEKE-RKRREEDEKRRRK 949
E + VKS + ++AL+ K Q ++E++E+E R+++ + ++K
Sbjct: 1804 LRSKLHEMEGAVKSKFKSTIAALEAKIAQ---------LEEQVEQEAREKQAATKSLKQK 1854
Query: 950 EEEERRMKLEMEAKRKQEEEERKKREDDEKRIQAEVEAQLARQKEEESQQQAVLEQERRD 1009
+++ + + L++E +RK E+ +++ E R++ QL RQ EE ++ + RR
Sbjct: 1855 DKKLKEILLQVEDERKMAEQYKEQAEKGNARVK-----QLKRQLEEAEEESQRINANRRK 1909
Query: 1010 RELALRIAQSEAELISDEAQA 1030
+ L A E + E A
Sbjct: 1910 LQRELDEATESNEAMGREVNA 1930
Score = 45.1 bits (105), Expect = 4e-04
Identities = 47/225 (20%), Positives = 108/225 (48%), Gaps = 30/225 (13%)
Query: 838 DGLVKVGTLKKRLDKFNEVVSVLKDGKPEMNKQIKNLEISIDTLMAKIKSTM---MTQEQ 894
+ L K+ L+ + E + + + + KQ ++L ++ L +++ T+ TQ++
Sbjct: 1115 NALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQE 1174
Query: 895 I----QKEYDALVKSSEELLSA--LQKKKQQEEEAERLRRIQEEMEKERKRREEDEKRRR 948
+ ++E L K+ +E + Q ++ +++ A+ + + E++E+ ++ + +K ++
Sbjct: 1175 LRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQ 1234
Query: 949 ---KEEEERRMKLEMEAKRKQEEEERKKRED-----------DEKRIQAEVEAQLAR-QK 993
KE + +L + + KQE E +KK+ + D +R +AE+ ++ + Q
Sbjct: 1235 TLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQN 1294
Query: 994 EEESQQQAVLEQERRDRELALRIA------QSEAELISDEAQADL 1032
E ES + E E + +LA +A Q EL+ +E + L
Sbjct: 1295 EVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKL 1339
Score = 45.1 bits (105), Expect = 4e-04
Identities = 46/192 (23%), Positives = 87/192 (45%), Gaps = 43/192 (22%)
Query: 893 EQIQKEYDALVKSSEELLSALQKKKQQEEEAERLRRIQEEMEKERKRREE------DEKR 946
+ ++ + D+ +K EE + L+K + Q ++ Q E+E R R+E + ++
Sbjct: 1634 KDLELQADSAIKGREEAIKQLRKLQAQ------MKDFQRELEDARASRDEIFATAKENEK 1687
Query: 947 RRKEEEERRMKLE-----MEAKRKQ---EEEE-----------RKKREDDEKRIQAEVEA 987
+ K E M+L+ E RKQ E+EE R +D+++R++A + A
Sbjct: 1688 KAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARI-A 1746
Query: 988 QLARQKEEESQQQAVLEQERRDRELALRIAQSEAELISDEAQADLALRRNDGTRPKMTPE 1047
QL + EEE + +R A +AE +S+E LA R+ + + +
Sbjct: 1747 QLEEELEEEQGNMEAMSDR-------VRKATQQAEQLSNE----LATERSTAQKNESARQ 1795
Query: 1048 QMAKEMSEFLSR 1059
Q+ ++ E S+
Sbjct: 1796 QLERQNKELRSK 1807
Score = 38.9 bits (89), Expect = 0.032
Identities = 61/324 (18%), Positives = 135/324 (41%), Gaps = 65/324 (20%)
Query: 845 TLKKRLDKFNEVVSVLKDGKPEMNKQIKNLEISIDTLMAKIKSTMMTQEQIQKEYDALVK 904
T + ++ K + + V+ D +++K+ K LE I L + +E+ K L
Sbjct: 982 TAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAE----EEEKAKNLTKLKN 1037
Query: 905 SSEELLSALQKKKQQEE----EAERLRRIQE------------------EMEKERKRREE 942
E ++S L+ + ++EE E E+L+R E E++ + ++EE
Sbjct: 1038 KHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEE 1097
Query: 943 ----------DEKRRRKEEEERRMKLEMEAKRKQEEEE-----RKKREDDEKRIQAEVEA 987
DE ++ ++ +LE QE+ + R K E ++ + E+EA
Sbjct: 1098 ELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEA 1157
Query: 988 QLARQKEEESQQQAVLEQE---RRDRELALRIAQSEAELISDEAQADLALRRNDGTRPKM 1044
+ + E++ +QE +R++E+ + + E S EAQ +++
Sbjct: 1158 --LKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKH-----AQ 1210
Query: 1045 TPEQMAKEMSEFLSRGPAVLATKAAAGTKKYDLSKWKYAELRDTINTSCDIELLAACREE 1104
E++ +++ +F K A K +L K K ++ + + ++ +L ++E
Sbjct: 1211 AVEELTEQLEQF----------KRA----KANLDKNKQTLEKENADLAGELRVLGQAKQE 1256
Query: 1105 FHRRLKVYHAWKSKNKKRNTETEQ 1128
+ K A + + + ++ E+
Sbjct: 1257 VEHKKKKLEAQVQELQSKCSDGER 1280
>gi|189083802 myosin VIIA isoform 2 [Homo sapiens]
Length = 2175
Score = 473 bits (1217), Expect = e-133
Identities = 322/971 (33%), Positives = 497/971 (51%), Gaps = 105/971 (10%)
Query: 50 PAEEDSKKDVEDNCSLMYLNEATLLHNIKVRYSKDRIYTYVANILIAVNPYFDIPKIYSS 109
P S VED L LNEA +L N+ +RY IYTY +IL+AVNPY + IYS
Sbjct: 58 PMHPTSVHGVEDMIRLGDLNEAGILRNLLIRYRDHLIYTYTGSILVAVNPY-QLLSIYSP 116
Query: 110 EAIKSYQGKSLGTRPPHVFAIADKAFRDMKVLKMSQSIIVSGESGAGKTENTKFVLRYLT 169
E I+ Y K +G PPH+FAIAD + +MK Q I+SGESGAGKTE+TK +L++L
Sbjct: 117 EHIRQYTNKKIGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLA 176
Query: 170 ESYGTGQDIDDRIVEANPLLEAFGNAKTVRNNNSSRFGKFVEIHFNEKSSVVGGFVSHYL 229
G I+ +++EA P+LEAFGNAKT+RN+NSSRFGK+++IHFN++ ++ G + YL
Sbjct: 177 AISGQHSWIEQQVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYL 236
Query: 230 LEKSRICVQGKEERNYHIFYRLCAGASEDIREKLHLSSPDNFRYLNRGCTRYFANKETDK 289
LEKSR+C Q +ERNYH+FY + G SED ++KL L ++ YL G D
Sbjct: 237 LEKSRVCRQALDERNYHVFYCMLEGMSEDQKKKLGLGQASDYNYLAMG-NCITCEGRVDS 295
Query: 290 QILQNRKSPEYLKAGSMKDPLLDDHGDFIRMCTAMKKIGLDDEEKLDLFRVVAGVLHLGN 349
Q N +S AMK + D E ++ +++A +LHLGN
Sbjct: 296 QEYANIRS-------------------------AMKVLMFTDTENWEISKLLAAILHLGN 330
Query: 350 IDFE-EAGSTSGGCNLKNKSAQSLEYCAELLGLDQDDLRVSLTTRVMLTTAGGTKGTVIK 408
+ +E C + + SL A LL ++ DL LT+R ++T +G +
Sbjct: 331 LQYEARTFENLDACEVL--FSPSLATAASLLEVNPPDLMSCLTSRTLIT-----RGETVS 383
Query: 409 VPLKVEQANNARDALAKTVYSHLFDHVVNRVNQCF------PFETSSYFIGVLDIAGFEY 462
PL EQA + RDA K +Y LF +V+++N + S IG+LDI GFE
Sbjct: 384 TPLSREQALDVRDAFVKGIYGRLFVWIVDKINAAIYKPPSQDVKNSRRSIGLLDIFGFEN 443
Query: 463 FEHNSFEQFCINYCNEKLQQFFNERILKEEQELYQKEGLGVNEVHYVDNQDCIDLIEAKL 522
F NSFEQ CIN+ NE LQQFF + K EQE Y E + + + DNQD +D+I K
Sbjct: 444 FAVNSFEQLCINFANEHLQQFFVRHVFKLEQEEYDLESIDWLHIEFTDNQDALDMIANKP 503
Query: 523 VGILDILDEENRLPQPSDQHFTSAVHQKHKDHFRLTIPRKSKLAVHRNIRDDEGFIIRHF 582
+ I+ ++DEE++ P+ +D ++ +HK + P+ + + F I HF
Sbjct: 504 MNIISLIDEESKFPKGTDTTMLHKLNSQHKLNANYIPPKNN---------HETQFGINHF 554
Query: 583 AGAVCYETTQFVEKNNDALHMSLESLICESRDKFIRELFESSTNNNKDTKQKAGKLSFIS 642
AG V YET F+EKN D LH + L+ SR+KFI+++F++ +T++++ LS
Sbjct: 555 AGIVYYETQGFLEKNRDTLHGDIIQLVHSSRNKFIKQIFQADVAMGAETRKRSPTLS--- 611
Query: 643 VGNKFKTQLNLLLDKLRSTGASFIRCIKPNLKMTSHHFEGAQILSQLQCSGMVSVLDLMQ 702
++FK L LL+ L + F+RCIKPN F+ + QL+ SGM+ + + +
Sbjct: 612 --SQFKRSLELLMRTLGACQPFFVRCIKPNEFKKPMLFDRHLCVRQLRYSGMMETIRIRR 669
Query: 703 GGYPSRASFHELYNMYKKYMP---DKLARLDPRLFCKALFKALGLNENDYKFGLTKVFFR 759
GYP R SF E Y+ +P + D R C+ + +A+ +D++ G TK+F +
Sbjct: 670 AGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRGTCQRMAEAVLGTHDDWQIGKTKIFLK 729
Query: 760 PGKFAEFDQIMKSDPDHLAELVKRVNHWLTCSRWKKVQWCSLSVIKLKNKIKYRAEACIK 819
D +++ + D + RV R K + + +KLKN A
Sbjct: 730 D----HHDMLLEVERD--KAITDRVILLQKVIRGFKDR---SNFLKLKN-------AATL 773
Query: 820 MQKTIRMWLCKRRHKPRIDGLVKVGTLKKRLDKFNEVVSVLKDGKPEMNKQIKNLEISID 879
+Q+ R C++ + GL+++G L RL + ++++Q + I
Sbjct: 774 IQRHWRGHNCRKNY-----GLMRLGFL--RLQALHR--------SRKLHQQYRLARQRII 818
Query: 880 TLMAKIKSTMMTQEQIQKEYDALVKSSEELLSALQKKKQQEEEAERLRRIQEEMEKERKR 939
A+ ++ ++ + + + L Q RR+ + + E
Sbjct: 819 QFQARCRAYLVRKAFRHRLWAVLT-------------VQAYARGMIARRLHQRLRAEYLW 865
Query: 940 REEDEKRRRKEEEERRMKLEMEAKRKQEEEERKKREDDEKRIQAEVEAQLARQKEEESQQ 999
R E EK R EEE +++ EM AK+ +EE ERK +E + + + E +L ++KE ++
Sbjct: 866 RLEAEKMRLAEEE--KLRKEMSAKKAKEEAERKHQERLAQLAREDAEREL-KEKEAARRK 922
Query: 1000 QAVLEQERRDR 1010
+ +LEQ R R
Sbjct: 923 KELLEQMERAR 933
>gi|189083800 myosin VIIA isoform 3 [Homo sapiens]
Length = 1204
Score = 473 bits (1217), Expect = e-133
Identities = 322/971 (33%), Positives = 497/971 (51%), Gaps = 105/971 (10%)
Query: 50 PAEEDSKKDVEDNCSLMYLNEATLLHNIKVRYSKDRIYTYVANILIAVNPYFDIPKIYSS 109
P S VED L LNEA +L N+ +RY IYTY +IL+AVNPY + IYS
Sbjct: 58 PMHPTSVHGVEDMIRLGDLNEAGILRNLLIRYRDHLIYTYTGSILVAVNPY-QLLSIYSP 116
Query: 110 EAIKSYQGKSLGTRPPHVFAIADKAFRDMKVLKMSQSIIVSGESGAGKTENTKFVLRYLT 169
E I+ Y K +G PPH+FAIAD + +MK Q I+SGESGAGKTE+TK +L++L
Sbjct: 117 EHIRQYTNKKIGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLA 176
Query: 170 ESYGTGQDIDDRIVEANPLLEAFGNAKTVRNNNSSRFGKFVEIHFNEKSSVVGGFVSHYL 229
G I+ +++EA P+LEAFGNAKT+RN+NSSRFGK+++IHFN++ ++ G + YL
Sbjct: 177 AISGQHSWIEQQVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYL 236
Query: 230 LEKSRICVQGKEERNYHIFYRLCAGASEDIREKLHLSSPDNFRYLNRGCTRYFANKETDK 289
LEKSR+C Q +ERNYH+FY + G SED ++KL L ++ YL G D
Sbjct: 237 LEKSRVCRQALDERNYHVFYCMLEGMSEDQKKKLGLGQASDYNYLAMG-NCITCEGRVDS 295
Query: 290 QILQNRKSPEYLKAGSMKDPLLDDHGDFIRMCTAMKKIGLDDEEKLDLFRVVAGVLHLGN 349
Q N +S AMK + D E ++ +++A +LHLGN
Sbjct: 296 QEYANIRS-------------------------AMKVLMFTDTENWEISKLLAAILHLGN 330
Query: 350 IDFE-EAGSTSGGCNLKNKSAQSLEYCAELLGLDQDDLRVSLTTRVMLTTAGGTKGTVIK 408
+ +E C + + SL A LL ++ DL LT+R ++T +G +
Sbjct: 331 LQYEARTFENLDACEVL--FSPSLATAASLLEVNPPDLMSCLTSRTLIT-----RGETVS 383
Query: 409 VPLKVEQANNARDALAKTVYSHLFDHVVNRVNQCF------PFETSSYFIGVLDIAGFEY 462
PL EQA + RDA K +Y LF +V+++N + S IG+LDI GFE
Sbjct: 384 TPLSREQALDVRDAFVKGIYGRLFVWIVDKINAAIYKPPSQDVKNSRRSIGLLDIFGFEN 443
Query: 463 FEHNSFEQFCINYCNEKLQQFFNERILKEEQELYQKEGLGVNEVHYVDNQDCIDLIEAKL 522
F NSFEQ CIN+ NE LQQFF + K EQE Y E + + + DNQD +D+I K
Sbjct: 444 FAVNSFEQLCINFANEHLQQFFVRHVFKLEQEEYDLESIDWLHIEFTDNQDALDMIANKP 503
Query: 523 VGILDILDEENRLPQPSDQHFTSAVHQKHKDHFRLTIPRKSKLAVHRNIRDDEGFIIRHF 582
+ I+ ++DEE++ P+ +D ++ +HK + P+ + + F I HF
Sbjct: 504 MNIISLIDEESKFPKGTDTTMLHKLNSQHKLNANYIPPKNN---------HETQFGINHF 554
Query: 583 AGAVCYETTQFVEKNNDALHMSLESLICESRDKFIRELFESSTNNNKDTKQKAGKLSFIS 642
AG V YET F+EKN D LH + L+ SR+KFI+++F++ +T++++ LS
Sbjct: 555 AGIVYYETQGFLEKNRDTLHGDIIQLVHSSRNKFIKQIFQADVAMGAETRKRSPTLS--- 611
Query: 643 VGNKFKTQLNLLLDKLRSTGASFIRCIKPNLKMTSHHFEGAQILSQLQCSGMVSVLDLMQ 702
++FK L LL+ L + F+RCIKPN F+ + QL+ SGM+ + + +
Sbjct: 612 --SQFKRSLELLMRTLGACQPFFVRCIKPNEFKKPMLFDRHLCVRQLRYSGMMETIRIRR 669
Query: 703 GGYPSRASFHELYNMYKKYMP---DKLARLDPRLFCKALFKALGLNENDYKFGLTKVFFR 759
GYP R SF E Y+ +P + D R C+ + +A+ +D++ G TK+F +
Sbjct: 670 AGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRGTCQRMAEAVLGTHDDWQIGKTKIFLK 729
Query: 760 PGKFAEFDQIMKSDPDHLAELVKRVNHWLTCSRWKKVQWCSLSVIKLKNKIKYRAEACIK 819
D +++ + D + RV R K + + +KLKN A
Sbjct: 730 D----HHDMLLEVERD--KAITDRVILLQKVIRGFKDR---SNFLKLKN-------AATL 773
Query: 820 MQKTIRMWLCKRRHKPRIDGLVKVGTLKKRLDKFNEVVSVLKDGKPEMNKQIKNLEISID 879
+Q+ R C++ + GL+++G L RL + ++++Q + I
Sbjct: 774 IQRHWRGHNCRKNY-----GLMRLGFL--RLQALHR--------SRKLHQQYRLARQRII 818
Query: 880 TLMAKIKSTMMTQEQIQKEYDALVKSSEELLSALQKKKQQEEEAERLRRIQEEMEKERKR 939
A+ ++ ++ + + + L Q RR+ + + E
Sbjct: 819 QFQARCRAYLVRKAFRHRLWAVLT-------------VQAYARGMIARRLHQRLRAEYLW 865
Query: 940 REEDEKRRRKEEEERRMKLEMEAKRKQEEEERKKREDDEKRIQAEVEAQLARQKEEESQQ 999
R E EK R EEE +++ EM AK+ +EE ERK +E + + + E +L ++KE ++
Sbjct: 866 RLEAEKMRLAEEE--KLRKEMSAKKAKEEAERKHQERLAQLAREDAEREL-KEKEAARRK 922
Query: 1000 QAVLEQERRDR 1010
+ +LEQ R R
Sbjct: 923 KELLEQMERAR 933
>gi|189083798 myosin VIIA isoform 1 [Homo sapiens]
Length = 2215
Score = 473 bits (1217), Expect = e-133
Identities = 322/971 (33%), Positives = 497/971 (51%), Gaps = 105/971 (10%)
Query: 50 PAEEDSKKDVEDNCSLMYLNEATLLHNIKVRYSKDRIYTYVANILIAVNPYFDIPKIYSS 109
P S VED L LNEA +L N+ +RY IYTY +IL+AVNPY + IYS
Sbjct: 58 PMHPTSVHGVEDMIRLGDLNEAGILRNLLIRYRDHLIYTYTGSILVAVNPY-QLLSIYSP 116
Query: 110 EAIKSYQGKSLGTRPPHVFAIADKAFRDMKVLKMSQSIIVSGESGAGKTENTKFVLRYLT 169
E I+ Y K +G PPH+FAIAD + +MK Q I+SGESGAGKTE+TK +L++L
Sbjct: 117 EHIRQYTNKKIGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLA 176
Query: 170 ESYGTGQDIDDRIVEANPLLEAFGNAKTVRNNNSSRFGKFVEIHFNEKSSVVGGFVSHYL 229
G I+ +++EA P+LEAFGNAKT+RN+NSSRFGK+++IHFN++ ++ G + YL
Sbjct: 177 AISGQHSWIEQQVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYL 236
Query: 230 LEKSRICVQGKEERNYHIFYRLCAGASEDIREKLHLSSPDNFRYLNRGCTRYFANKETDK 289
LEKSR+C Q +ERNYH+FY + G SED ++KL L ++ YL G D
Sbjct: 237 LEKSRVCRQALDERNYHVFYCMLEGMSEDQKKKLGLGQASDYNYLAMG-NCITCEGRVDS 295
Query: 290 QILQNRKSPEYLKAGSMKDPLLDDHGDFIRMCTAMKKIGLDDEEKLDLFRVVAGVLHLGN 349
Q N +S AMK + D E ++ +++A +LHLGN
Sbjct: 296 QEYANIRS-------------------------AMKVLMFTDTENWEISKLLAAILHLGN 330
Query: 350 IDFE-EAGSTSGGCNLKNKSAQSLEYCAELLGLDQDDLRVSLTTRVMLTTAGGTKGTVIK 408
+ +E C + + SL A LL ++ DL LT+R ++T +G +
Sbjct: 331 LQYEARTFENLDACEVL--FSPSLATAASLLEVNPPDLMSCLTSRTLIT-----RGETVS 383
Query: 409 VPLKVEQANNARDALAKTVYSHLFDHVVNRVNQCF------PFETSSYFIGVLDIAGFEY 462
PL EQA + RDA K +Y LF +V+++N + S IG+LDI GFE
Sbjct: 384 TPLSREQALDVRDAFVKGIYGRLFVWIVDKINAAIYKPPSQDVKNSRRSIGLLDIFGFEN 443
Query: 463 FEHNSFEQFCINYCNEKLQQFFNERILKEEQELYQKEGLGVNEVHYVDNQDCIDLIEAKL 522
F NSFEQ CIN+ NE LQQFF + K EQE Y E + + + DNQD +D+I K
Sbjct: 444 FAVNSFEQLCINFANEHLQQFFVRHVFKLEQEEYDLESIDWLHIEFTDNQDALDMIANKP 503
Query: 523 VGILDILDEENRLPQPSDQHFTSAVHQKHKDHFRLTIPRKSKLAVHRNIRDDEGFIIRHF 582
+ I+ ++DEE++ P+ +D ++ +HK + P+ + + F I HF
Sbjct: 504 MNIISLIDEESKFPKGTDTTMLHKLNSQHKLNANYIPPKNN---------HETQFGINHF 554
Query: 583 AGAVCYETTQFVEKNNDALHMSLESLICESRDKFIRELFESSTNNNKDTKQKAGKLSFIS 642
AG V YET F+EKN D LH + L+ SR+KFI+++F++ +T++++ LS
Sbjct: 555 AGIVYYETQGFLEKNRDTLHGDIIQLVHSSRNKFIKQIFQADVAMGAETRKRSPTLS--- 611
Query: 643 VGNKFKTQLNLLLDKLRSTGASFIRCIKPNLKMTSHHFEGAQILSQLQCSGMVSVLDLMQ 702
++FK L LL+ L + F+RCIKPN F+ + QL+ SGM+ + + +
Sbjct: 612 --SQFKRSLELLMRTLGACQPFFVRCIKPNEFKKPMLFDRHLCVRQLRYSGMMETIRIRR 669
Query: 703 GGYPSRASFHELYNMYKKYMP---DKLARLDPRLFCKALFKALGLNENDYKFGLTKVFFR 759
GYP R SF E Y+ +P + D R C+ + +A+ +D++ G TK+F +
Sbjct: 670 AGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRGTCQRMAEAVLGTHDDWQIGKTKIFLK 729
Query: 760 PGKFAEFDQIMKSDPDHLAELVKRVNHWLTCSRWKKVQWCSLSVIKLKNKIKYRAEACIK 819
D +++ + D + RV R K + + +KLKN A
Sbjct: 730 D----HHDMLLEVERD--KAITDRVILLQKVIRGFKDR---SNFLKLKN-------AATL 773
Query: 820 MQKTIRMWLCKRRHKPRIDGLVKVGTLKKRLDKFNEVVSVLKDGKPEMNKQIKNLEISID 879
+Q+ R C++ + GL+++G L RL + ++++Q + I
Sbjct: 774 IQRHWRGHNCRKNY-----GLMRLGFL--RLQALHR--------SRKLHQQYRLARQRII 818
Query: 880 TLMAKIKSTMMTQEQIQKEYDALVKSSEELLSALQKKKQQEEEAERLRRIQEEMEKERKR 939
A+ ++ ++ + + + L Q RR+ + + E
Sbjct: 819 QFQARCRAYLVRKAFRHRLWAVLT-------------VQAYARGMIARRLHQRLRAEYLW 865
Query: 940 REEDEKRRRKEEEERRMKLEMEAKRKQEEEERKKREDDEKRIQAEVEAQLARQKEEESQQ 999
R E EK R EEE +++ EM AK+ +EE ERK +E + + + E +L ++KE ++
Sbjct: 866 RLEAEKMRLAEEE--KLRKEMSAKKAKEEAERKHQERLAQLAREDAEREL-KEKEAARRK 922
Query: 1000 QAVLEQERRDR 1010
+ +LEQ R R
Sbjct: 923 KELLEQMERAR 933
>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
sapiens]
Length = 1937
Score = 456 bits (1174), Expect = e-128
Identities = 353/1174 (30%), Positives = 570/1174 (48%), Gaps = 127/1174 (10%)
Query: 7 VWAPHPTDGFQMGNIVDIGPDSLTIEPLNQKGKTFLALINQVFPAEEDSKKDVEDNCSLM 66
V+ P + + I +T++ + G T +QVFP +ED +
Sbjct: 40 VFVAEPKESYVKSTIQSKEGGKVTVK--TEGGATLTVREDQVFPMNPPKYDKIEDMAMMT 97
Query: 67 YLNEATLLHNIKVRYSKDRIYTYVANILIAVNPYFDIPKIYSSEAIKSYQGKSLGTRPPH 126
+L+E +L+N+K RY+ IYTY + VNPY +P +Y E + +Y+GK PPH
Sbjct: 98 HLHEPGVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLP-VYKPEVVAAYRGKKRQEAPPH 156
Query: 127 VFAIADKAFRDMKVLKMSQSIIVSGESGAGKTENTKFVLRYLTESYGTGQD--------- 177
+F+I+D A++ M + +QSI+++GESGAGKT NTK V++Y TG+
Sbjct: 157 IFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKDESGKMQ 216
Query: 178 --IDDRIVEANPLLEAFGNAKTVRNNNSSRFGKFVEIHFNEKSSVVGGFVSHYLLEKSRI 235
++D+I+ ANPLLEAFGNAKTVRN+NSSRFGKF+ IHF + + YLLEKSR+
Sbjct: 217 GTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRV 276
Query: 236 CVQGKEERNYHIFYRLCAGASEDIREKLHLSSPDNFRYLNRGCTRYFANKETDKQILQNR 295
Q K ER+YHIFY++ + D+ E L +++ N
Sbjct: 277 TFQLKAERSYHIFYQITSNKKPDLIEMLLITT--------------------------NP 310
Query: 296 KSPEYLKAGSMKDPLLDDHGDFIRMCTAMKKIGLDDEEKLDLFRVVAGVLHLGNIDFE-- 353
++ G + P +DD + + +A+ +G EEK+ ++++ V+H GN+ F+
Sbjct: 311 YDYAFVSQGEITVPSIDDQEELMATDSAIDILGFTPEEKVSIYKLTGAVMHYGNMKFKQK 370
Query: 354 --EAGSTSGGCNLKNKSAQSLEYCAELLGLDQDDLRVSLT-TRVMLTTAGGTKGTVIKVP 410
E + G + +K+A L L+ DL +L RV + TKG
Sbjct: 371 QREEQAEPDGTEVADKAAY-------LQSLNSADLLKALCYPRVKVGNEYVTKGQT---- 419
Query: 411 LKVEQANNARDALAKTVYSHLFDHVVNRVNQCFPF-ETSSYFIGVLDIAGFEYFEHNSFE 469
V+Q NA ALAK VY +F +V R+NQ + YFIGVLDIAGFE F+ NS E
Sbjct: 420 --VQQVYNAVGALAKAVYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLE 477
Query: 470 QFCINYCNEKLQQFFNERILKEEQELYQKEGLGVNEVHY-VDNQDCIDLIEAKLVGILDI 528
Q CIN+ NEKLQQFFN + EQE Y+KEG+ + + +D CI+LIE K +GI I
Sbjct: 478 QLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIE-KPLGIFSI 536
Query: 529 LDEENRLPQPSDQHFTSAVHQKH---KDHFRLTIPRKSKLAVHRNIRDDEGFIIRHFAGA 585
L+EE P+ +D F + ++ +H +F+ K K H F + H+AG
Sbjct: 537 LEEECMFPKATDTSFKNKLYDQHLGKSANFQKPKVVKGKAEAH--------FSLIHYAGT 588
Query: 586 VCYETTQFVEKNNDALHMSLESLICESRDKFIRELFESSTNNNKDTKQKAGK----LSFI 641
V Y T +++KN D L+ ++ L +S K + LF + + D+ K G SF
Sbjct: 589 VDYNITGWLDKNKDPLNDTVVGLYQKSAMKTLASLFSTYASAEADSSAKKGAKKKGSSFQ 648
Query: 642 SVGNKFKTQLNLLLDKLRSTGASFIRCIKPNLKMTSHHFEGAQILSQLQCSGMVSVLDLM 701
+V F+ LN L+ LRST F+RCI PN T E +L QL+C+G++ + +
Sbjct: 649 TVSALFRENLNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRIC 708
Query: 702 QGGYPSRASFHELYNMYKKYMPDKLAR---LDPRLFCKALFKALGLNENDYKFGLTKVFF 758
+ G+PSR + + YK + +D + + L ++ ++ YKFG TKVFF
Sbjct: 709 RKGFPSRILYGDFKQRYKVLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFF 768
Query: 759 RPGKFAEFDQIMKSDPDHLAELVKRVNHWLTCSRW-KKVQWCSLSVIKLKNKIKYRAEAC 817
+ G +++ + LA+++ R C + +V++ K+ R EA
Sbjct: 769 KAGLLGLLEEMR---DEKLAQIITRTQ--AVCRGFLMRVEY---------QKMLQRREAL 814
Query: 818 IKMQKTIRMWLCKRRHKP------RIDGLVKVGTLKKRLDKFNEVVSVLKDGKPEMNKQI 871
+Q +R ++ +H P +I L+K +K + E KD + +
Sbjct: 815 FCIQYNVRAFM-NVKHWPWMKLFFKIKPLLKSAETEKEMATMKEEFQKTKDELAKSEAKR 873
Query: 872 KNLEISIDTLMAKIKSTMMTQEQIQKEYDALVKSSEELLSALQKKKQQE-------EEAE 924
K LE + TL +K Q Q+Q E D+L + E ++ K Q E E AE
Sbjct: 874 KELEEKMVTL---LKEKNDLQLQVQSEADSLADAEERCEQLIKNKIQLEAKIKEVTERAE 930
Query: 925 RLRRIQEEMEKERKRREEDEKRRRKEEEERRMKLEMEAKRKQEEEERKKREDDEKRIQAE 984
I E+ ++++ E++ +K+ ++ + L K K E + K +E E
Sbjct: 931 EEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDE 990
Query: 985 VEAQLARQKE--EESQQQAVLE-QERRDRELALRIAQSEAELISDEAQADLALR---RND 1038
A+L+++K+ +E+ QQ + + Q D+ L A+++ E D+ + L R D
Sbjct: 991 TIAKLSKEKKALQETHQQTLDDLQAEEDKVNILTKAKTKLEQQVDDLEGSLEQEKKLRMD 1050
Query: 1039 GTRPKMTPE---QMAKEMSEFLSRGPAVLATKAAAGTKKYDLSKWKYAELRD----TINT 1091
R K E ++A+E + + L K K++++S +++ D I
Sbjct: 1051 LERAKRKLEGDLKLAQESTMDMENDKQQLDEKLE--KKEFEISN-LISKIEDEQAVEIQL 1107
Query: 1092 SCDIELLAACREEFHRRLKVYHAWKSKNKKRNTE 1125
I+ L A EE ++ A ++K +K+ ++
Sbjct: 1108 QKKIKELQARIEELGEEIEAERASRAKAEKQRSD 1141
Score = 67.0 bits (162), Expect = 1e-10
Identities = 82/345 (23%), Positives = 148/345 (42%), Gaps = 41/345 (11%)
Query: 805 KLKNKIKYRA---EACIKMQKTIRMWLCKRRHKPRIDGLVKVGTLKKRLDKFNEVVSVLK 861
K K K++ + E ++ +K +RM L R K +++G +K+ E ++
Sbjct: 1025 KAKTKLEQQVDDLEGSLEQEKKLRMDL--ERAKRKLEGDLKLA---------QESTMDME 1073
Query: 862 DGKPEMNKQIKNLEISIDTLMAKIKSTMMTQEQIQKEYDALVKSSEELLSALQKKKQQEE 921
+ K +++++++ E I L++KI+ + Q+QK+ L EEL +E
Sbjct: 1074 NDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEEL--------GEEI 1125
Query: 922 EAERLRRIQEEMEKERKRREEDEKRRRKEEEERRMKLEMEAKRKQEEEERKKRED-DEKR 980
EAER R + E ++ RE +E R EE ++E +K+E E +K R D +E
Sbjct: 1126 EAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEAT 1185
Query: 981 IQAEVEAQLARQKEEESQQQ------------AVLEQERRDRELALRIAQSEAELISDEA 1028
+Q E R+K +S + LE+E+ + ++ S AE IS +A
Sbjct: 1186 LQHEAMVAALRKKHADSMAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAIS-KA 1244
Query: 1029 QADL---ALRRNDGTRPKMTPEQMAKEMSEFLSRGPAVLATKAAAGTKKYDLSKWKYAEL 1085
+ +L D T E+ + + L+ A L T+A +++ D ++L
Sbjct: 1245 KGNLEKMCRSLEDQVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQL 1304
Query: 1086 RDTINTSCD--IELLAACREEFHRRLKVYHAWKSKNKKRNTETEQ 1128
+ S EL EE + + HA +S + EQ
Sbjct: 1305 SRSKQASTQQIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQ 1349
Score = 52.4 bits (124), Expect = 3e-06
Identities = 47/184 (25%), Positives = 93/184 (50%), Gaps = 15/184 (8%)
Query: 855 EVVSVLKDGKPEMNKQIKNLEISIDTLMAKIKSTMMTQEQIQKEYDALVKSSEELLSALQ 914
EV+ ++ + + K I + + + L K + T E+++K + VK + L +
Sbjct: 1746 EVIQESRNAEEKAKKAITDAAMMAEELK-KEQDTSAHLERMKKNLEQTVKDLQHRLDEAE 1804
Query: 915 K------KKQQEEEAERLRRIQEEMEKERKRREEDEKRRRKEEEERRMKLEMEAKRKQEE 968
+ KKQ ++ R+R ++ E+E E+KR E K RK ERR+K E+ + +++
Sbjct: 1805 QLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRK--HERRVK-ELTYQTEEDR 1861
Query: 969 EERKKREDDEKRIQAEVEAQLARQKEEESQQQAVLEQERRDRELALRIAQSEAELISDEA 1028
+ + +D ++QA+V++ + +E E Q A L + R+ L+ EAE +D A
Sbjct: 1862 KNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNANLSKFRK-----LQHELEEAEERADIA 1916
Query: 1029 QADL 1032
++ +
Sbjct: 1917 ESQV 1920
Score = 48.1 bits (113), Expect = 5e-05
Identities = 45/198 (22%), Positives = 94/198 (47%), Gaps = 13/198 (6%)
Query: 846 LKKRLDKFNEVVSVLKDGKPEMNKQIKNLEI---SIDTLMAKIKS----TMMTQEQIQKE 898
L K+ F++V+S K E +++ + S+ T + K+K+ ++ E +++E
Sbjct: 1445 LDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVYEESLDQLETLRRE 1504
Query: 899 YDALVKSSEELLSALQKKKQQEEEAERLRRIQEEMEKERKRREEDEKRRRKEEEERRMKL 958
L + +L + + +Q E E++++ E+ + E + E+ + + EE + +++
Sbjct: 1505 NKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRI 1564
Query: 959 EMEAKRKQEEEERKKREDDEKRIQAEVEAQLARQKEEESQQQAVLEQERRDRELALRIAQ 1018
++E + + E +RK E DE E++ Q+ L+ E R R ALR+ +
Sbjct: 1565 QLELNQVKSEVDRKIAEKDE-----EIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKK 1619
Query: 1019 S-EAELISDEAQADLALR 1035
E +L E Q + A R
Sbjct: 1620 KMEGDLNEMEIQLNHANR 1637
Score = 42.0 bits (97), Expect = 0.004
Identities = 43/198 (21%), Positives = 92/198 (46%), Gaps = 24/198 (12%)
Query: 863 GKPEMNKQIKNLEISIDTLMAKIKSTMMTQEQIQKEY----DALVKSSEEL-------LS 911
G+ ++ +Q+ +E + L A+I+ T EQ ++ L+ +SE + S
Sbjct: 1666 GQEDLKEQLAIVERRANLLQAEIEELWATLEQTERSRKIAEQELLDASERVQLLHTQNTS 1725
Query: 912 ALQKKKQQEEEAERLRRIQEEMEKERKRREEDEKRRRKEEEERRMKLEMEAKRKQEEEER 971
+ KK+ E + +L+ EE+ +E + EE K+ + +L+ E E
Sbjct: 1726 LINTKKKLENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERM 1785
Query: 972 KKR-EDDEKRIQAEVEAQLARQKEEESQQQAVLEQERRDRELALRIAQSEAELISDE--- 1027
KK E K +Q + +E++Q A+ +++ ++L R+ + E E+ +++
Sbjct: 1786 KKNLEQTVKDLQ---------HRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRN 1836
Query: 1028 AQADLALRRNDGTRPKMT 1045
A+A LR+++ ++T
Sbjct: 1837 AEAVKGLRKHERRVKELT 1854
Score = 31.6 bits (70), Expect = 5.1
Identities = 35/143 (24%), Positives = 64/143 (44%), Gaps = 29/143 (20%)
Query: 832 RHKPRIDGLVKVGTLKKRLDKFNEVVSVLKDGKPEMNK---QIKNLEISIDTLMAKIKST 888
R K ++ VK L+ RLD+ ++ LK GK ++ K +++ LE ++ +
Sbjct: 1784 RMKKNLEQTVK--DLQHRLDEAEQLA--LKGGKKQIQKLEARVRELEGEVENEQKRNAEA 1839
Query: 889 MMTQEQIQKEYDALVKSSEE----------LLSALQKK----KQQEEEAE--------RL 926
+ + ++ L +EE L+ LQ K K+Q EEAE +
Sbjct: 1840 VKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNANLSKF 1899
Query: 927 RRIQEEMEKERKRREEDEKRRRK 949
R++Q E+E+ +R + E + K
Sbjct: 1900 RKLQHELEEAEERADIAESQVNK 1922
>gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]
Length = 1995
Score = 455 bits (1170), Expect = e-127
Identities = 359/1205 (29%), Positives = 588/1205 (48%), Gaps = 164/1205 (13%)
Query: 7 VWAPHPTDGFQMGNIVDIGPDSLTIEPLNQKGKTFLALINQVFPAEEDSKKDVEDNCSLM 66
VW P GF+ + D G + +E L + G+ +Q+ ED L
Sbjct: 56 VWVPSELHGFEAAALRDEGEEEAEVE-LAESGRRLRLPRDQIQRMNPPKFSKAEDMAELT 114
Query: 67 YLNEATLLHNIKVRYSKDRIYTYVANILIAVNPYFDIPKIYSSEAIKSYQGKSLGTRPPH 126
LNEA++LHN++ RY IYTY + +NPY +P IY+ ++ Y+GK PPH
Sbjct: 115 CLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLP-IYTEAIVEMYRGKKRHEVPPH 173
Query: 127 VFAIADKAFRDMKVLKMSQSIIVSGESGAGKTENTKFVLRYLT---------ESYGTGQD 177
V+A+ + A+R M + QSI+ +GESGAGKTENTK V++YL + G +
Sbjct: 174 VYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVPGE 233
Query: 178 IDDRIVEANPLLEAFGNAKTVRNNNSSRFGKFVEIHFNEKSSVVGGFVSHYLLEKSRICV 237
++ ++++ANP+LEAFGNAKTV+N+NSSRFGKF+ I+F+ +VG + YLLEKSR
Sbjct: 234 LERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLEKSRAIR 293
Query: 238 QGKEERNYHIFYRLCAGASEDIREKLHLSSPDNFRYLNRGCTRYFANKETDKQILQNRKS 297
Q K+E ++HIFY+L GA E ++ L L ++R+L G + ++ ++++ Q
Sbjct: 294 QAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPS---SSPGQERELFQETLE 350
Query: 298 PEYLKAGSMKDPLLDDHGDFIRMCTAMKKIGLDDEEKLDLFRVVAGVLHLGNIDFEEAGS 357
+++ +G EE + + R+V+ VL GNI + +
Sbjct: 351 -------------------------SLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERN 385
Query: 358 TSGGCNLKNKSAQSLEYCAELLGLDQDDL-RVSLTTRVMLTTAGGTKGTVIKVPLKVEQA 416
T N +AQ L LLGL D R LT R+ + + V K K EQA
Sbjct: 386 TDQATMPDNTAAQKL---CRLLGLGVTDFSRALLTPRIKVG-----RDYVQKAQTK-EQA 436
Query: 417 NNARDALAKTVYSHLFDHVVNRVNQCF---PFETSSYFIGVLDIAGFEYFEHNSFEQFCI 473
+ A +ALAK Y LF +V R+N+ P + +S F+G+LDIAGFE F+ NSFEQ CI
Sbjct: 437 DFALEALAKATYERLFRWLVLRLNRALDRSPRQGAS-FLGILDIAGFEIFQLNSFEQLCI 495
Query: 474 NYCNEKLQQFFNERILKEEQELYQKEGLGVNEVHY-VDNQDCIDLIE--AKLVGILDILD 530
NY NEKLQQ FN + EQE YQ+EG+ + + +D Q CIDLIE A G+L +LD
Sbjct: 496 NYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLD 555
Query: 531 EENRLPQPSDQHFTSAVHQKHKDHFRLTIPRKSKLAVHRNIRDDEGFIIRHFAGAVCYET 590
EE P+ +D+ F V Q+ H + P R++RD F + H+AG V Y+
Sbjct: 556 EECWFPKATDKSFVEKVAQEQGGHPKFQRP--------RHLRDQADFSVLHYAGKVDYKA 607
Query: 591 TQFVEKNNDALHMSLESLICESRDKFIRELFES----------STNNNKDTKQKAGKLSF 640
+++ KN D L+ ++ +L+ +S D+ E+++ S+ + + + F
Sbjct: 608 NEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKDVEGIVGLEQVSSLGDGPPGGRPRRGMF 667
Query: 641 ISVGNKFKTQLNLLLDKLRSTGASFIRCIKPNLKMTSHHFEGAQILSQLQCSGMVSVLDL 700
+VG +K L+ L+ L +T SF+RCI PN + + E +L QL+C+G++ + +
Sbjct: 668 RTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRI 727
Query: 701 MQGGYPSRASFHELYNMYKKYMPDKLAR--LDPRLFCKALFKALGLNENDYKFGLTKVFF 758
+ G+P+R F E Y+ P+ + + +D + C+ + +AL L+ N Y+ G +K+FF
Sbjct: 728 CRQGFPNRILFQEFRQRYEILTPNAIPKGFMDGKQACEKMIQALELDPNLYRVGQSKIFF 787
Query: 759 RPGKFAEFDQ-------------------------IMKSDPDHLAELVKRVN-------- 785
R G A+ ++ K A V + N
Sbjct: 788 RAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAAYLKLR 847
Query: 786 HWLTCSRWKKVQWCSLSVIKLKNKIKYRAEACIKMQKTIRMWLCKRRHKPRIDGLV---- 841
HW + KV+ L V + ++ RA+ ++QK + R + G V
Sbjct: 848 HWQWWRLFTKVK-PLLQVTRQDEVLQARAQ---ELQKVQELQQQSAREVGELQGRVAQLE 903
Query: 842 -KVGTLKKRLDKFNEVVSVLKDGKPEMNKQIKNLEISIDTLMAKIKSTMMTQEQIQKEYD 900
+ L ++L E+ + ++ + + + + LE+ + L A++ Q+Q E
Sbjct: 904 EERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKK 963
Query: 901 ALVKSSEELLSALQ------------------KKKQQEEEAERLRRIQEEMEKERKRREE 942
L + +EL + L+ K K+ EE+ L ++ KERK E+
Sbjct: 964 RLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLED 1023
Query: 943 ---DEKRRRKEEEER-----RMKLEMEAKRKQEEEERKKREDDEKRIQAEVEAQLARQKE 994
+ + EEEE+ +++L+ EA E+ +K E + ++ +L R+ +
Sbjct: 1024 RLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELE-----KLKRRLD 1078
Query: 995 EESQ--QQAVLEQERRDRELALRIAQSEAELISDEAQADLALRRNDGTRPKMTPEQMAKE 1052
ES Q+ ++EQ++R EL ++ + E EL QA LA ++G + + +E
Sbjct: 1079 GESSELQEQMVEQQQRAEELRAQLGRKEEEL-----QAALARAEDEGGARAQLLKSL-RE 1132
Query: 1053 MSEFLSRGPAVLATKAAAGTK----KYDLSKWKYA---ELRDTINTSCDIELLAACREEF 1105
L+ L ++ A TK + DL + A EL DT++++ + L + RE+
Sbjct: 1133 AQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQE 1192
Query: 1106 HRRLK 1110
LK
Sbjct: 1193 VTELK 1197
Score = 57.8 bits (138), Expect = 7e-08
Identities = 59/222 (26%), Positives = 117/222 (52%), Gaps = 29/222 (13%)
Query: 845 TLKKRLDKFNEVVSVLKDGKPEMNKQIKNLE---ISIDTLMAKIKSTMMTQEQIQKEYDA 901
T + ++ KF E + +L+D +++K+ K LE + A+ + + + +++ +Y+A
Sbjct: 992 TTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEA 1051
Query: 902 LVKSSEELLSALQKKKQQEEEAERLRR--------IQEEMEKERKRREEDEKRRRKEEEE 953
+ E+ L+K+++ +E E+L+R +QE+M ++++R EE + ++EEE
Sbjct: 1052 TIADMED---RLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEE 1108
Query: 954 RRMKLEMEAKRKQEEEERKKREDDEKRIQAEVEAQLARQKEE-ESQQQAVLEQERRDREL 1012
++A + E+E R K ++ E +A LA +E+ ES++ A + E++ R+L
Sbjct: 1109 ------LQAALARAEDEGGARAQLLKSLR-EAQAALAEAQEDLESERVARTKAEKQRRDL 1161
Query: 1013 -----ALRIAQSEAELISDEAQADL-ALRRNDGTRPKMTPEQ 1048
ALR + E L S AQ +L + R + T K T E+
Sbjct: 1162 GEELEALR-GELEDTLDSTNAQQELRSKREQEVTELKKTLEE 1202
Score = 57.0 bits (136), Expect = 1e-07
Identities = 71/250 (28%), Positives = 111/250 (44%), Gaps = 44/250 (17%)
Query: 842 KVGTLKKRLDKFNEVVSVLKDG--KPEMNKQ-IKNLEISIDTLMAKIKSTMMTQEQIQKE 898
KV +L K K+ ++ ++D K E +Q ++ L+ +D ++++ M+ Q+Q +E
Sbjct: 1038 KVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEE 1097
Query: 899 YDA-LVKSSEELLSAL-----------QKKKQQEEEAERLRRIQEEMEKERKRREEDEKR 946
A L + EEL +AL Q K E L QE++E ER R + EK+
Sbjct: 1098 LRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQ 1157
Query: 947 RRKEEEE--------------RRMKLEMEAKRKQEEEERKKREDDEKRI-QAEVEAQLAR 991
RR EE + E+ +KR+QE E KK ++E RI +A V+ R
Sbjct: 1158 RRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQR 1217
Query: 992 QKEEESQQQAVLEQERRDR------ELALRIAQSE--AELISDEAQADLALRRNDGTRPK 1043
+ + LEQ RR + LAL SE AEL S L R +G + +
Sbjct: 1218 HGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSS------LQTARQEGEQRR 1271
Query: 1044 MTPEQMAKEM 1053
E +E+
Sbjct: 1272 RRLELQLQEV 1281
Score = 48.9 bits (115), Expect = 3e-05
Identities = 61/256 (23%), Positives = 117/256 (45%), Gaps = 50/256 (19%)
Query: 864 KPEMNKQIKNLEISIDTLMAKIKSTMMT---QEQI----QKEYDALVKSSEELL----SA 912
+ + KQ ++L ++ L +++ T+ + Q+++ ++E L K+ EE +A
Sbjct: 1151 RTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAA 1210
Query: 913 LQKKKQQEEEAERLRRIQEEMEKERKRREEDEKRR--------------------RKEEE 952
+Q+ +Q+ +A L + E++E+ R+ + EK R R+E E
Sbjct: 1211 VQELRQRHGQA--LGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGE 1268
Query: 953 ERRMKLEMEAKRKQEEEERKKREDDEKRIQAEVEAQLAR-QKEEESQQQAVLEQERRDRE 1011
+RR +LE++ +E + R D +R +AE +L R Q E E+ A+ E E +
Sbjct: 1269 QRRRRLELQL------QEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIR 1322
Query: 1012 LALRIAQSEA------ELISDEAQADLALRRNDGTRPKMTPEQMAKEMSEFLSRGPAVLA 1065
L+ ++ +EA EL+ +E +A LAL G+R + + A + A
Sbjct: 1323 LSKELSSTEAQLHDAQELLQEETRAKLAL----GSRVRAMEAEAAGLREQLEEEAAARER 1378
Query: 1066 TKAAAGTKKYDLSKWK 1081
T + LS+W+
Sbjct: 1379 AGRELQTAQAQLSEWR 1394
Score = 45.4 bits (106), Expect = 3e-04
Identities = 44/221 (19%), Positives = 97/221 (43%), Gaps = 34/221 (15%)
Query: 861 KDGKPEMNKQIKNLEISIDTLMA----------KIKSTMMTQEQIQKEYDALVKSSEELL 910
++ + E+ +Q + L ++ L++ +++ EQ + A V E+ L
Sbjct: 1513 QEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDEL 1572
Query: 911 SALQKKKQQEEEAERLRRIQEEMEKERKRREEDEKRRRKEEEERRMKLEMEAKRKQEE-- 968
+A + K + E + + Q E + + + +E+RR+ ++ R ++E + +RKQ
Sbjct: 1573 TAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLA 1632
Query: 969 -EERKKREDDEKRIQAEVEA--------------------QLARQKEEESQQQAVLEQER 1007
RKK E + + ++A++ + +L R+ EE + + +
Sbjct: 1633 VAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQN 1692
Query: 1008 RDRELALRIAQSEAELISDE-AQADLALRRNDGTRPKMTPE 1047
R+ E L+ ++E + +E A +D A R+ R +M E
Sbjct: 1693 RESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADE 1733
Score = 43.5 bits (101), Expect = 0.001
Identities = 51/263 (19%), Positives = 111/263 (42%), Gaps = 20/263 (7%)
Query: 834 KPRIDGLVKVGTLKKRLDKFNEVVSVLKDGKPEMNKQIKNLEISIDTLMAKIKSTMMTQE 893
+ R + K+ + L+ + ++ + ++K++ + E + ++ +
Sbjct: 1290 RARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKL 1349
Query: 894 QIQKEYDALVKSSEELLSALQKKKQQEEEAERLRRIQEEMEKERKRREEDEKRRRKEEEE 953
+ A+ + L L+++ E A R + + E +RR+E+E + EE
Sbjct: 1350 ALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEE 1409
Query: 954 RRMKLEMEA----KRKQEEEERKKR-EDDEKRIQAEVEAQLARQKEEESQQQAVLEQERR 1008
R + EA +R E+ E R E +R+Q E++ + E Q+Q V E++
Sbjct: 1410 ARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELD---DATMDLEQQRQLVSTLEKK 1466
Query: 1009 DRELALRIAQSEAEL---ISDEAQADLALRRNDGTRPKMT----PEQMAKEMSEFLSRG- 1060
R+ +A+ +A + + + +A+ R + +T EQ A+E E +R
Sbjct: 1467 QRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRAL 1526
Query: 1061 ----PAVLATKAAAGTKKYDLSK 1079
A+L++K G ++L +
Sbjct: 1527 RAELEALLSSKDDVGKSVHELER 1549
Score = 43.5 bits (101), Expect = 0.001
Identities = 50/239 (20%), Positives = 107/239 (44%), Gaps = 37/239 (15%)
Query: 846 LKKRLDKFNEVVSVLKDGKPEMNKQIKNLEISIDTLMAKIKSTMMTQEQIQKEYDALVKS 905
L+ L++ ++ GK E KQ++ ++ + L +++ T ++E+I + +
Sbjct: 1639 LEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQN----RE 1694
Query: 906 SEELLSALQKKKQQEEEAERLRRIQEEMEKERKRREEDEKRRRKEEE------------E 953
SE+ L L EAE LR +E +R RR+ + R +E E
Sbjct: 1695 SEKRLKGL--------EAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILE 1746
Query: 954 RRMKLE-----MEAKRKQEEEERKKREDDEKRIQAEVEA---QLARQKEEESQQQAVLEQ 1005
+ +LE +E + ++E+ + D +++ +VE+ +L+ ++ ++ ++ +Q
Sbjct: 1747 EKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQ 1806
Query: 1006 -ERRDRELALRIAQSEAELISDEAQADLALRRNDGTRPKMTPEQMAKEMSEFLSRGPAV 1063
ER+ +EL R+ + +A + AL ++ EQ+ +E E + G V
Sbjct: 1807 LERQIQELRGRLGEEDAGARARHKMTIAALE----SKLAQAEEQLEQETRERILSGKLV 1861
Score = 42.4 bits (98), Expect = 0.003
Identities = 52/222 (23%), Positives = 97/222 (43%), Gaps = 24/222 (10%)
Query: 855 EVVSVLKDGKPEMNKQIKNLEISIDTLMAKIKSTMMTQE---QIQKEYDALVKSSEE--- 908
E L+ G+ + + E L K ++ + ++Q+E D E+
Sbjct: 1399 EEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQ 1458
Query: 909 LLSALQKKKQQ------EEEAERLRRIQEEMEKERKRREEDEK-----RRRKEEEERRMK 957
L+S L+KK+++ EE+A LR ++E E + RE + + R +EE+E R +
Sbjct: 1459 LVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREE 1518
Query: 958 LEME--AKRKQEEEERKKREDDEKRI-QAEVEAQLARQKEEESQQQAV-LEQERRDRELA 1013
LE + A R + E ++D K + + E ++A Q + + Q LE E E A
Sbjct: 1519 LERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDA 1578
Query: 1014 LRIAQSEAELISDEAQADLALRRNDGTRPKMTPEQMAKEMSE 1055
+ + + + + DL R G + Q+AK++ +
Sbjct: 1579 KLRLEVTVQALKTQHERDLQGRDEAGEERR---RQLAKQLRD 1617
Score = 41.6 bits (96), Expect = 0.005
Identities = 57/244 (23%), Positives = 114/244 (46%), Gaps = 34/244 (13%)
Query: 834 KPRIDGLVKVGTLKKRLDKFNEVVSVLKDGKPEMNKQIKNL--EISID-TLMAKIKS-TM 889
K +++G ++G L++ L++ +L D ++ Q+++L E+S + + AK +S
Sbjct: 1748 KRQLEG--RLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQ 1805
Query: 890 MTQEQIQK------EYDALVKSSEEL-LSALQKKKQQEEEA------ERL------RRIQ 930
+ QIQ+ E DA ++ ++ ++AL+ K Q EE ER+ RR +
Sbjct: 1806 QLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAE 1865
Query: 931 EEMEK-----ERKRREEDEKRRRKEEEERRMKLEMEAKRKQEEEERKKREDDEKRIQAEV 985
+ +++ E +RR D+ R + E+ R+K +++ + ++ EEE + + +R+Q E+
Sbjct: 1866 KRLKEVVLQVEEERRVADQLRDQLEKGNLRVK-QLKRQLEEAEEEASRAQAGRRRLQREL 1924
Query: 986 EAQLARQKEEESQQQAVLEQERRDRELAL--RIAQSEAELISDEAQADLALRRNDGTRPK 1043
E + E +++ L R L R + L A + A G+ P
Sbjct: 1925 E-DVTESAESMNREVTTLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEEAQPGSGPS 1983
Query: 1044 MTPE 1047
PE
Sbjct: 1984 PEPE 1987
>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
sapiens]
Length = 1940
Score = 455 bits (1170), Expect = e-127
Identities = 359/1213 (29%), Positives = 598/1213 (49%), Gaps = 139/1213 (11%)
Query: 16 FQMGNIVDIGPDSLTIEPLNQKGKTFLALINQVFPAEEDSKKDVEDNCSLMYLNEATLLH 75
+ G I +T+E + +T + V+ +ED L +LNE +L+
Sbjct: 47 YAKGKIKSSQDGKVTVE--TEDNRTLVVKPEDVYAMNPPKFDRIEDMAMLTHLNEPAVLY 104
Query: 76 NIKVRYSKDRIYTYVANILIAVNPYFDIPKIYSSEAIKSYQGKSLGTRPPHVFAIADKAF 135
N+K RY+ IYTY + VNPY +P +Y+ E ++ Y+GK PPH+F+I+D A+
Sbjct: 105 NLKDRYTSWMIYTYSGLFCVTVNPYKWLP-VYNPEVVEGYRGKKRQEAPPHIFSISDNAY 163
Query: 136 RDMKVLKMSQSIIVSGESGAGKTENTKFVLRYLTESYGTGQ-----------DIDDRIVE 184
+ M + +QSI+++GESGAGKT NTK V++Y TG ++D+I+
Sbjct: 164 QFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAATGDLAKKKDSKMKGTLEDQIIS 223
Query: 185 ANPLLEAFGNAKTVRNNNSSRFGKFVEIHFNEKSSVVGGFVSHYLLEKSRICVQGKEERN 244
ANPLLEAFGNAKTVRN+NSSRFGKF+ IHF + + YLLEKSR+ Q K ER+
Sbjct: 224 ANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERS 283
Query: 245 YHIFYRLCAGASEDIREKLHLSS-PDNFRYLNRGCTRYFANKETDKQILQNRKSPEYLKA 303
YHIFY++ + ++ E L +++ P ++ ++++G E L A
Sbjct: 284 YHIFYQILSNKKPELIELLLITTNPYDYPFISQG---------------------EILVA 322
Query: 304 GSMKDPLLDDHGDFIRMCTAMKKIGLDDEEKLDLFRVVAGVLHLGNIDFE----EAGSTS 359
+DD + + +A+ +G EEK L+++ V+H GN+ F+ E +
Sbjct: 323 S------IDDAEELLATDSAIDILGFTPEEKSGLYKLTGAVMHYGNMKFKQKQREEQAEP 376
Query: 360 GGCNLKNKSAQSLEYCAELLGLDQDDLRVSLT-TRVMLTTAGGTKGTVIKVPLKVEQANN 418
G + +K+A L+GL+ DL +L RV + TKG V+Q ++
Sbjct: 377 DGTEVADKTAY-------LMGLNSSDLLKALCFPRVKVGNEYVTKGQT------VDQVHH 423
Query: 419 ARDALAKTVYSHLFDHVVNRVNQCFPFETS-SYFIGVLDIAGFEYFEHNSFEQFCINYCN 477
A +AL+K+VY LF +V R+NQ + +FIGVLDIAGFE FE+NS EQ CIN+ N
Sbjct: 424 AVNALSKSVYEKLFLWMVTRINQQLDTKLPRQHFIGVLDIAGFEIFEYNSLEQLCINFTN 483
Query: 478 EKLQQFFNERILKEEQELYQKEGLGVNEVHY-VDNQDCIDLIEAKLVGILDILDEENRLP 536
EKLQQFFN + EQE Y+KEG+ + + +D CI+LIE K +GI IL+EE P
Sbjct: 484 EKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIE-KPMGIFSILEEECMFP 542
Query: 537 QPSDQHFTSAVHQKH---KDHFRLTIPRKSKLAVHRNIRDDEGFIIRHFAGAVCYETTQF 593
+ +D F + ++ +H ++F+ K + H F + H+AG V Y + +
Sbjct: 543 KATDTSFKNKLYDQHLGKSNNFQKPKVVKGRAEAH--------FSLIHYAGTVDYSVSGW 594
Query: 594 VEKNNDALHMSLESLICESRDKFIRELFESSTNNNKDT-KQKAGK---LSFISVGNKFKT 649
+EKN D L+ ++ L +S ++ + L+ + + D+ K+K K SF +V F+
Sbjct: 595 LEKNKDPLNETVVGLYQKSSNRLLAHLYATFATADADSGKKKVAKKKGSSFQTVSALFRE 654
Query: 650 QLNLLLDKLRSTGASFIRCIKPNLKMTSHHFEGAQILSQLQCSGMVSVLDLMQGGYPSRA 709
LN L+ LR+T F+RCI PN T E + +L QL+C+G++ + + + G+P+R
Sbjct: 655 NLNKLMSNLRTTHPHFVRCIIPNETKTPGAMEHSLVLHQLRCNGVLEGIRICRKGFPNRI 714
Query: 710 SFHELYNMYKKYMPDKLAR---LDPRLFCKALFKALGLNENDYKFGLTKVFFRPGKFAEF 766
+ + Y+ + +D + C+ L ++ ++ YKFG TKVFF+ G
Sbjct: 715 LYGDFKQRYRVLNASAIPEGQFIDSKKACEKLLASIDIDHTQYKFGHTKVFFKAGLLGTL 774
Query: 767 DQIMKSDPDHLAELVKRVNHWLTCSRWKKVQWCSLSVIKLK-NKIKYRAEACIKMQKTIR 825
+++ D LA+L+ R C +++++ K+ R E+ +Q IR
Sbjct: 775 EEMR---DDRLAKLITRTQ-----------AVCRGFLMRVEFQKMVQRRESIFCIQYNIR 820
Query: 826 MWLCKRRHKP------RIDGLVKVGTLKKRLDKFNEVVSVLKDGKPEMNKQIKNLEISID 879
++ +H P +I L+K +K + E KD + + K LE +
Sbjct: 821 SFM-NVKHWPWMKLFFKIKPLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKLV 879
Query: 880 TLMAKIKSTMMTQEQIQKE--------YDALVKSSEELLSALQKKKQQEEEAERLRRIQE 931
TL+ + K+ + Q Q + E D L+K+ +L + K K+ E AE I
Sbjct: 880 TLVQE-KNDLQLQVQAESENLLDAEERCDQLIKAKFQLEA---KIKEVTERAEDEEEINA 935
Query: 932 EMEKERKRREEDEKRRRKEEEERRMKLEMEAKRKQEEEERKKREDDEKRIQAEVEAQLAR 991
E+ ++++ E++ +K+ ++ + L K K E + K +E E A+L R
Sbjct: 936 ELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEELSGLDETIAKLTR 995
Query: 992 QKE--EESQQQAVLE-QERRDRELALRIAQSEAELISDEAQADLALR---RNDGTRPKMT 1045
+K+ +E+ QQA+ + Q D+ +L +S+ E ++ ++ L R D R K
Sbjct: 996 EKKALQEAHQQALDDLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRK 1055
Query: 1046 PE---QMAKEMSEFLSRGPAVLATKAAAGTKKYDLSKWKYAELRDTINTSCDIELLAACR 1102
E ++A+E L L + KK D ++Y +L+ + + L
Sbjct: 1056 LEGDLKLAQESILDLENDKQQLDER----LKKKD---FEYCQLQSKVEDEQTLGL----- 1103
Query: 1103 EEFHRRLKVYHA-WKSKNKKRNTETEQRAPKSVTDYDFAPFLNN-SPQQNPAAQIPARQR 1160
+F +++K A + ++ E RA D+A L S + A + + Q
Sbjct: 1104 -QFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSERLEEAGGVTSTQI 1162
Query: 1161 EIEMNRQQRFFRI 1173
E+ R+ F ++
Sbjct: 1163 ELNKKREAEFLKL 1175
Score = 60.8 bits (146), Expect = 8e-09
Identities = 63/262 (24%), Positives = 122/262 (46%), Gaps = 28/262 (10%)
Query: 802 SVIKLKNKIKYRAE---ACIKMQKTIRMWLCKRRHKPRIDGLVKVGTLKKRLDKFNEVVS 858
S+ K K+K++ + E + ++ +K +R+ L R+K +++G +K+ E +
Sbjct: 1020 SLNKTKSKLEQQVEDLESSLEQEKKLRVDL--ERNKRKLEGDLKLA---------QESIL 1068
Query: 859 VLKDGKPEMNKQIKNLEISIDTLMAKIKSTMMTQEQIQKEYDALVKSSEELLSALQKKKQ 918
L++ K ++++++K + L +K++ Q QK+ L EEL +
Sbjct: 1069 DLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEEL--------E 1120
Query: 919 QEEEAERLRRIQEEMEKERKRREEDEKRRRKEEEERRMKLEMEAKRKQEEEERKKRED-D 977
+E EAER R + E ++ RE +E R EE ++E +K+E E K R D +
Sbjct: 1121 EEIEAERATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLE 1180
Query: 978 EKRIQAEVEAQLARQKEEESQQQAVLEQERRDR-ELALRIAQSEAELISDEAQADLALRR 1036
E +Q E R+K +S + + + R + L +SE +L D DL+
Sbjct: 1181 EATLQHEAMVAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEID----DLSSSM 1236
Query: 1037 NDGTRPKMTPEQMAKEMSEFLS 1058
++ K E++ + + + LS
Sbjct: 1237 ESVSKSKANLEKICRTLEDQLS 1258
Score = 53.5 bits (127), Expect = 1e-06
Identities = 81/381 (21%), Positives = 160/381 (41%), Gaps = 47/381 (12%)
Query: 817 CIKMQKTIRMWLCKRRHKPRIDGLVKVGTLKKRLDKFNEVVSVLKDGKPEMNKQIKNLEI 876
C ++KT K R+ G +V L +++ N + + L + +K + +
Sbjct: 1412 CASLEKT----------KQRLQG--EVEDLMVDVERANSLAAALDKKQRNFDKVLAEWKT 1459
Query: 877 SIDTLMAKIKSTMMTQEQIQKEYDALVKSSEELLSALQKKKQQ-----EEEAERLRRIQE 931
+ A++++++ + E L + EE L L+ K++ +E A+ +I E
Sbjct: 1460 KCEESQAELEASLKESRSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQIAE 1519
Query: 932 ------EMEKERKRRE----------EDEKRRRKEEEERRMKLEMEAKRKQEEEERKKRE 975
E+EK RK+ E E+ + + EE + +++++E + + E +RK E
Sbjct: 1520 NGKTIHELEKSRKQIELEKADIQLALEEAEAALEHEEAKILRIQLELTQVKSEIDRKIAE 1579
Query: 976 DDEKRIQAEVEAQLARQKEEESQQQAVLEQERRDRELALRIAQS-EAELISDEAQADLAL 1034
DE E+E + Q+ L+ E R R A+R+ + E +L E Q A
Sbjct: 1580 KDE-----EIEQLKRNYQRTVETMQSALDAEVRSRNEAIRLKKKMEGDLNEIEIQLSHAN 1634
Query: 1035 RRNDGTRPKMTPEQ-MAKEMSEFLS---RGPAVLATKAAAGTKKYDLSKWKYAELRDTIN 1090
R+ T + Q K+ L RG L + A ++ +L + + ELR T+
Sbjct: 1635 RQAAETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEVEELRATLE 1694
Query: 1091 TSCDIELLAACR-EEFHRRLKVYHAWKSK--NKKRNTETEQRAPKSVTDYDFAPFLNNSP 1147
+ LA + + R+++ H + + K+ ET+ +S + D + N+
Sbjct: 1695 QTERARKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQLQSEVE-DASRDARNAE 1753
Query: 1148 QQNPAAQIPARQREIEMNRQQ 1168
++ A A E+ ++Q
Sbjct: 1754 EKAKKAITDAAMMAEELKKEQ 1774
Score = 51.6 bits (122), Expect = 5e-06
Identities = 73/359 (20%), Positives = 141/359 (39%), Gaps = 35/359 (9%)
Query: 836 RIDGLVKVGT-LKKRLDKFNEVVSVLKDGKPEMNKQIKNLEISIDTLMAKIKSTMMTQEQ 894
+ID L +V L+K +F + L ++K NLE TL ++ E+
Sbjct: 1207 QIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEE 1266
Query: 895 IQKEYDALVKSSEELLSALQKKKQQEEEAERLRRIQEEMEKERKRREEDEKRRRKEEEER 954
IQ+ L L + + +Q EE E + ++ ++ E+ KR+ +EE +
Sbjct: 1267 IQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENKA 1326
Query: 955 RMKL---------EMEAKRKQEEEERKKREDDEKRI-QAEVEAQLARQKEEESQQQAVLE 1004
+ L + + R+Q EEE++ + + ++ + +A E R K E Q E
Sbjct: 1327 KNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEE 1386
Query: 1005 QERRDRELALRIAQSEAELISDEAQADLALRRNDGTRPKMTPEQMAKEMSEFLSRGPAVL 1064
E ++LA R+ SE ++ + A+ + T +++ E+ + +
Sbjct: 1387 LEEAKKKLAQRLQDSEEQVEAVNAKC---------ASLEKTKQRLQGEVEDLMVDVERAN 1437
Query: 1065 ATKAAAGTKKYD----LSKWK------YAELRDTINTSCDIEL-LAACREEFHRRLKVYH 1113
+ AA K+ + L++WK AEL ++ S + L + + L
Sbjct: 1438 SLAAALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQLE 1497
Query: 1114 AWKSKNKKRNTE----TEQRAPKSVTDYDFAPFLNNSPQQNPAAQIPARQREIEMNRQQ 1168
K +NK E TEQ A T ++ + Q+ + E + ++
Sbjct: 1498 TVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAEAALEHEE 1556
Score = 46.2 bits (108), Expect = 2e-04
Identities = 45/183 (24%), Positives = 88/183 (48%), Gaps = 22/183 (12%)
Query: 882 MAKIKSTMMTQEQIQKEYDALVKSSEELLSALQK------KKQQEEEAERLRRIQEEMEK 935
+ K + T E+++K + VK + L ++ KKQ ++ R+R ++ E+E
Sbjct: 1770 LKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLETRIRELEFELEG 1829
Query: 936 ERKRREEDEKRRRKEEEERRMKLEMEAKRKQEEEERKKREDDEKRIQAEVEAQLARQKEE 995
E+K+ E K RK ERR+K E+ + +++ + + +D ++Q +V++ + +E
Sbjct: 1830 EQKKNTESVKGLRK--YERRVK-ELTYQSEEDRKNVLRLQDLVDKLQVKVKSYKRQAEEA 1886
Query: 996 ESQQQAVLEQERRDRELALRIAQSEAELISDEAQADLALRRNDGTRPK---MTPEQMAKE 1052
+ Q A L + R+ ++ EL E +AD+A + + R K T +M
Sbjct: 1887 DEQANAHLTKFRK----------AQHELEEAEERADIAESQVNKLRAKTRDFTSSRMVVH 1936
Query: 1053 MSE 1055
SE
Sbjct: 1937 ESE 1939
>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 454 bits (1168), Expect = e-127
Identities = 357/1179 (30%), Positives = 572/1179 (48%), Gaps = 132/1179 (11%)
Query: 7 VWAPHPTDGFQMGNIVDIGPDSLTIEPLNQKGKTFLALINQVFPAEEDSKKDVEDNCSLM 66
V+ P + F G I +T++ + G T +QVFP +ED +
Sbjct: 38 VFVAEPKESFVKGTIQSREGGKVTVK--TEGGATLTVKDDQVFPMNPPKYDKIEDMAMMT 95
Query: 67 YLNEATLLHNIKVRYSKDRIYTYVANILIAVNPYFDIPKIYSSEAIKSYQGKSLGTRPPH 126
+L+E +L+N+K RY+ IYTY + VNPY +P +Y E + +Y+GK PPH
Sbjct: 96 HLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLP-VYKPEVVTAYRGKKRQEAPPH 154
Query: 127 VFAIADKAFRDMKVLKMSQSIIVSGESGAGKTENTKFVLRYLTESYGTGQD--------- 177
+F+I+D A++ M + +QSI+++GESGAGKT NTK V++Y TG+
Sbjct: 155 IFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKEEITSGK 214
Query: 178 ----IDDRIVEANPLLEAFGNAKTVRNNNSSRFGKFVEIHFNEKSSVVGGFVSHYLLEKS 233
++D+I+ ANPLLEAFGNAKTVRN+NSSRFGKF+ IHF + + YLLEKS
Sbjct: 215 IQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLEKS 274
Query: 234 RICVQGKEERNYHIFYRLCAGASEDIREKLHLSSPDNFRYLNRGCTRYFANKETDKQILQ 293
R+ Q K ER+YHIFY++ + ++ E L +++
Sbjct: 275 RVVFQLKAERSYHIFYQITSNKKPELIEMLLITT-------------------------- 308
Query: 294 NRKSPEYLKAGSMKDPLLDDHGDFIRMCTAMKKIGLDDEEKLDLFRVVAGVLHLGNIDFE 353
N ++ G + +DD + + +A+ +G +EEK+ ++++ V+H GN+ F+
Sbjct: 309 NPYDYPFVSQGEISVASIDDQEELMATDSAIDILGFTNEEKVSIYKLTGAVMHYGNLKFK 368
Query: 354 ----EAGSTSGGCNLKNKSAQSLEYCAELLGLDQDDLRVSLT-TRVMLTTAGGTKGTVIK 408
E + G + +K+A L L+ DL +L RV + TKG
Sbjct: 369 QKQREEQAEPDGTEVADKAAY-------LQSLNSADLLKALCYPRVKVGNEYVTKGQT-- 419
Query: 409 VPLKVEQANNARDALAKTVYSHLFDHVVNRVNQCFPF-ETSSYFIGVLDIAGFEYFEHNS 467
VEQ +NA ALAK VY +F +V R+NQ + YFIGVLDIAGFE F+ NS
Sbjct: 420 ----VEQVSNAVGALAKAVYEKMFLWMVARINQQLDTKQPRQYFIGVLDIAGFEIFDFNS 475
Query: 468 FEQFCINYCNEKLQQFFNERILKEEQELYQKEGLGVNEVHY-VDNQDCIDLIEAKLVGIL 526
EQ CIN+ NEKLQQFFN + EQE Y+KEG+ + + +D CI+LIE K +GI
Sbjct: 476 LEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIE-KPMGIF 534
Query: 527 DILDEENRLPQPSDQHFTSAVHQKH---KDHFRLTIPRKSKLAVHRNIRDDEGFIIRHFA 583
IL+EE P+ +D F + ++ +H +F+ K K H F + H+A
Sbjct: 535 SILEEECMFPKATDTSFKNKLYDQHLGKSANFQKPKVVKGKAEAH--------FALIHYA 586
Query: 584 GAVCYETTQFVEKNNDALHMSLESLICESRDKFIRELF--------ESSTNNNKDTKQKA 635
G V Y T ++EKN D L+ ++ L +S K + +LF E + K +K
Sbjct: 587 GVVDYNITGWLEKNKDPLNETVVGLYQKSAMKTLAQLFSGAQTAEGEGAGGGAKKGGKKK 646
Query: 636 GKLSFISVGNKFKTQLNLLLDKLRSTGASFIRCIKPNLKMTSHHFEGAQILSQLQCSGMV 695
G SF +V F+ LN L+ LRST F+RCI PN T E +L QL+C+G++
Sbjct: 647 GS-SFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVL 705
Query: 696 SVLDLMQGGYPSRASFHELYNMYKKYMPDKLAR---LDPRLFCKALFKALGLNENDYKFG 752
+ + + G+PSR + + YK + +D + + L ++ ++ YKFG
Sbjct: 706 EGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFG 765
Query: 753 LTKVFFRPGKFAEFDQIMKSDPDHLAELVKRVNHWLTCSRWKKVQWCSLSVIKLKNKIKY 812
TKVFF+ G +++ D LA+L+ R C + L+ ++ + ++
Sbjct: 766 HTKVFFKAGLLGLLEEMR---DDKLAQLITRTQ--ARCRGF-------LARVEYQRMVE- 812
Query: 813 RAEACIKMQKTIRMWLCKRRHKP------RIDGLVKVGTLKKRLDKFNEVVSVLKDGKPE 866
R EA +Q IR ++ +H P +I L+K +K + E +KD +
Sbjct: 813 RREAIFCIQYNIRSFM-NVKHWPWMKLFFKIKPLLKSAETEKEMATMKEEFQKIKDELAK 871
Query: 867 MNKQIKNLEISIDTLMAKIKSTMMTQEQIQKEYDALVKSSEELLSALQKKKQQE------ 920
+ K LE + TL +K Q Q+Q E + L + E ++ K Q E
Sbjct: 872 SEAKRKELEEKMVTL---LKEKNDLQLQVQAEAEGLADAEERCDQLIKTKIQLEAKIKEV 928
Query: 921 -EEAERLRRIQEEMEKERKRREEDEKRRRKEEEERRMKLEMEAKRKQEEEERKKREDDEK 979
E AE I E+ ++++ E++ +K+ ++ + L K K E + K +E
Sbjct: 929 TERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEM 988
Query: 980 RIQAEVEAQLARQKE--EESQQQAVLE-QERRDRELALRIAQSEAELISDEAQADLALR- 1035
E A+L ++K+ +E+ QQ + + Q D+ L A+ + E D+ + L
Sbjct: 989 AGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEK 1048
Query: 1036 --RNDGTRPKMTPE---QMAKEMSEFLSRGPAVLATKAAAGTKKYDLSKWKYAELRDT-- 1088
R D R K E ++A+E + L K K++++S + +++ D
Sbjct: 1049 KLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLK--KKEFEISNLQ-SKIEDEQA 1105
Query: 1089 --INTSCDIELLAACREEFHRRLKVYHAWKSKNKKRNTE 1125
I I+ L A EE ++ A ++K +K+ ++
Sbjct: 1106 LGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSD 1144
Score = 70.5 bits (171), Expect = 1e-11
Identities = 69/266 (25%), Positives = 125/266 (46%), Gaps = 26/266 (9%)
Query: 795 KVQWCSLSVIKLKNKIKYRAEACIKMQKTIRMWLCKRRHKPRIDGLVKVGTLKKRLDKFN 854
KV + + IKL+ ++ E ++ +K +RM L R K +++G +K+
Sbjct: 1022 KVNTLTKAKIKLEQQVD-DLEGSLEQEKKLRMDL--ERAKRKLEGDLKLA---------Q 1069
Query: 855 EVVSVLKDGKPEMNKQIKNLEISIDTLMAKIKSTMMTQEQIQKEYDALVKSSEELLSALQ 914
E + +++ K ++++++K E I L +KI+ Q+QK+ L EEL
Sbjct: 1070 ESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEEL----- 1124
Query: 915 KKKQQEEEAERLRRIQEEMEKERKRREEDEKRRRKEEEERRMKLEMEAKRKQEEEERKKR 974
++E EAER R + E ++ RE +E R EE ++E +K+E E +K R
Sbjct: 1125 ---EEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMR 1181
Query: 975 ED-DEKRIQAEVEAQLARQKEEESQQQAVLEQERRDR-ELALRIAQSEAELISDEAQADL 1032
D +E +Q E A R+K +S + + + R + L +SE ++ D DL
Sbjct: 1182 RDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEID----DL 1237
Query: 1033 ALRRNDGTRPKMTPEQMAKEMSEFLS 1058
A ++ K E+M + + + LS
Sbjct: 1238 ASNVETVSKAKGNLEKMCRTLEDQLS 1263
Score = 48.5 bits (114), Expect = 4e-05
Identities = 42/150 (28%), Positives = 78/150 (52%), Gaps = 9/150 (6%)
Query: 883 AKIKSTMMTQEQIQKEYDALVKSSEELLSALQKKKQQEEEAERLRRIQEEMEKERKRREE 942
A ++ EQ K+ + +E+L KK+ Q+ EA R+R ++ E+E E+KR E
Sbjct: 1783 AHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEA-RVRELEGEVESEQKRNAE 1841
Query: 943 DEKRRRKEEEERRMKLEMEAKRKQEEEERKKREDDEKRIQAEVEAQLARQKEEESQQQAV 1002
K RK ERR+K E+ + +++ + + +D ++QA+V++ + +E E Q
Sbjct: 1842 AVKGLRK--HERRVK-ELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTN 1898
Query: 1003 LEQERRDRELALRIAQSEAELISDEAQADL 1032
L + R+ L+ EAE +D A++ +
Sbjct: 1899 LAKFRK-----LQHELEEAEERADIAESQV 1923
Score = 44.7 bits (104), Expect = 6e-04
Identities = 63/302 (20%), Positives = 135/302 (44%), Gaps = 30/302 (9%)
Query: 846 LKKRLDKFNEVVSVLKDGKPEMNKQIKNLEI---SIDTLMAKIKS----TMMTQEQIQKE 898
L K+ F+++++ K E + +++ + S+ T + KIK+ ++ E +++E
Sbjct: 1448 LDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRE 1507
Query: 899 YDALVKSSEELLSALQKKKQQEEEAERLRRIQEEMEKERKRREEDEKRRRKEEEERRMKL 958
L + +L + + ++ E E++++ E+ + E + E+ + + EE + +++
Sbjct: 1508 NKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRI 1567
Query: 959 EMEAKRKQEEEERKKREDDEKRIQAEVEAQLARQKEEESQQQAVLEQERRDRELALRIAQ 1018
++E + + E +RK E DE E++ Q+ L+ E R R A+R+ +
Sbjct: 1568 QLELNQVKSEVDRKIAEKDE-----EIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKK 1622
Query: 1019 S-EAELISDEAQADLALR-RNDGTRPKMTPEQMAKEMSEFLS---RGPAVLATKAAAGTK 1073
E +L E Q + A R + R + + K+ L R L + A +
Sbjct: 1623 KMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVER 1682
Query: 1074 KYDLSKWKYAELRDTINTS------CDIELLAACREEFHRRLKVYHAWKSK--NKKRNTE 1125
+ +L + + ELR T+ + + ELL A R+++ H + N K+ E
Sbjct: 1683 RANLLQAEIEELRATLEQTERSRKIAEQELLDA-----SERVQLLHTQNTSLINTKKKLE 1737
Query: 1126 TE 1127
T+
Sbjct: 1738 TD 1739
Score = 42.7 bits (99), Expect = 0.002
Identities = 63/341 (18%), Positives = 129/341 (37%), Gaps = 27/341 (7%)
Query: 846 LKKRLDKFNEVVSVLKDGKPEMNKQIKNLEISIDTLMAKIKSTMMTQEQIQKEYDALVKS 905
+K +D V + K + K + LE + L +K + + + L
Sbjct: 1230 MKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTE 1289
Query: 906 SEELLSALQKKKQQEEEAERLRRIQEEMEKERKRREEDEKRRRK--EEEERRMKLEMEAK 963
S E L +K+ + R ++ + +E KR+ E+E + + + + + +
Sbjct: 1290 SGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLL 1349
Query: 964 RKQEEEERKKREDDEKRI-QAEVEAQLARQKEEESQQQAVLEQERRDRELALRIAQSEAE 1022
R+Q EEE++ + + ++ + +A E R K E Q E E ++LA R+ +E
Sbjct: 1350 REQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEH 1409
Query: 1023 LISDEAQADLALRRNDGTRPKMTPEQMAKEMSEFLSRGPAVLATKAAAGTKKYD----LS 1078
+ + A+ + T +++ E+ + + A AA K+ + L+
Sbjct: 1410 VEAVNAKC---------ASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILA 1460
Query: 1079 KWK------YAELRDTINTSCDIEL-LAACREEFHRRLKVYHAWKSKNKKRNTE----TE 1127
+WK +AEL + + + L + + L K +NK E TE
Sbjct: 1461 EWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTE 1520
Query: 1128 QRAPKSVTDYDFAPFLNNSPQQNPAAQIPARQREIEMNRQQ 1168
Q A ++ Q+ Q + E + ++
Sbjct: 1521 QIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEE 1561
Score = 39.3 bits (90), Expect = 0.025
Identities = 32/190 (16%), Positives = 84/190 (44%), Gaps = 15/190 (7%)
Query: 854 NEVVSVLKDGKPEMNKQIKNLEISIDTLMAKIKSTMMTQEQIQKEYDALVKSSEELLSAL 913
+E V +L + K LE I + +++ + +++ + + + L
Sbjct: 1716 SERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEEL 1775
Query: 914 QKKKQQEEEAERLRRIQEEMEKERKRREEDEKR----------RRKEEEERRMKLEMEAK 963
+K++ ER+++ E+ K+ + R ++ ++ ++ E R ++ E+E++
Sbjct: 1776 KKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESE 1835
Query: 964 RKQEEEERKKREDDEKRIQAEVEAQLARQKEEESQQQAVLEQERRDRELALRIAQSEAEL 1023
+K+ E K E+R++ +L Q EE+ + L+ + ++ + +AE
Sbjct: 1836 QKRNAEAVKGLRKHERRVK-----ELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEE 1890
Query: 1024 ISDEAQADLA 1033
+++ +LA
Sbjct: 1891 AEEQSNTNLA 1900
Score = 38.9 bits (89), Expect = 0.032
Identities = 46/175 (26%), Positives = 80/175 (45%), Gaps = 21/175 (12%)
Query: 832 RHKPRIDGLVKVGTLKKRLDKFNEVVSVLKDGKPEMNKQIKNLEISIDTLMAKIKSTMMT 891
R K ++ VK L+ RLD+ ++ LK GK KQI+ LE + L +++S
Sbjct: 1787 RMKKNMEQTVK--DLQLRLDEAEQLA--LKGGK----KQIQKLEARVRELEGEVESEQKR 1838
Query: 892 QEQIQKEYDALVKSSEELLSALQKKKQQEEEAERLRRIQEEMEKERKRREEDEKRRRKE- 950
+ K + +EL Q EE+ + + R+Q+ ++K + + + KR+ +E
Sbjct: 1839 NAEAVKGLRKHERRVKELTY------QTEEDRKNILRLQDLVDK-LQAKVKSYKRQAEEA 1891
Query: 951 EEERRMKLEMEAKRKQEEEERKKREDDEKRIQAEVEAQLARQKEEESQQQAVLEQ 1005
EE+ L K + E EE ++R D AE + R K E + + E+
Sbjct: 1892 EEQSNTNLAKFRKLQHELEEAEERAD-----IAESQVNKLRVKSREVHTKVISEE 1941
>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 454 bits (1168), Expect = e-127
Identities = 357/1179 (30%), Positives = 572/1179 (48%), Gaps = 132/1179 (11%)
Query: 7 VWAPHPTDGFQMGNIVDIGPDSLTIEPLNQKGKTFLALINQVFPAEEDSKKDVEDNCSLM 66
V+ P + F G I +T++ + G T +QVFP +ED +
Sbjct: 38 VFVAEPKESFVKGTIQSREGGKVTVK--TEGGATLTVKDDQVFPMNPPKYDKIEDMAMMT 95
Query: 67 YLNEATLLHNIKVRYSKDRIYTYVANILIAVNPYFDIPKIYSSEAIKSYQGKSLGTRPPH 126
+L+E +L+N+K RY+ IYTY + VNPY +P +Y E + +Y+GK PPH
Sbjct: 96 HLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLP-VYKPEVVTAYRGKKRQEAPPH 154
Query: 127 VFAIADKAFRDMKVLKMSQSIIVSGESGAGKTENTKFVLRYLTESYGTGQD--------- 177
+F+I+D A++ M + +QSI+++GESGAGKT NTK V++Y TG+
Sbjct: 155 IFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKEEITSGK 214
Query: 178 ----IDDRIVEANPLLEAFGNAKTVRNNNSSRFGKFVEIHFNEKSSVVGGFVSHYLLEKS 233
++D+I+ ANPLLEAFGNAKTVRN+NSSRFGKF+ IHF + + YLLEKS
Sbjct: 215 IQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLEKS 274
Query: 234 RICVQGKEERNYHIFYRLCAGASEDIREKLHLSSPDNFRYLNRGCTRYFANKETDKQILQ 293
R+ Q K ER+YHIFY++ + ++ E L +++
Sbjct: 275 RVVFQLKAERSYHIFYQITSNKKPELIEMLLITT-------------------------- 308
Query: 294 NRKSPEYLKAGSMKDPLLDDHGDFIRMCTAMKKIGLDDEEKLDLFRVVAGVLHLGNIDFE 353
N ++ G + +DD + + +A+ +G +EEK+ ++++ V+H GN+ F+
Sbjct: 309 NPYDYPFVSQGEISVASIDDQEELMATDSAIDILGFTNEEKVSIYKLTGAVMHYGNLKFK 368
Query: 354 ----EAGSTSGGCNLKNKSAQSLEYCAELLGLDQDDLRVSLT-TRVMLTTAGGTKGTVIK 408
E + G + +K+A L L+ DL +L RV + TKG
Sbjct: 369 QKQREEQAEPDGTEVADKAAY-------LQSLNSADLLKALCYPRVKVGNEYVTKGQT-- 419
Query: 409 VPLKVEQANNARDALAKTVYSHLFDHVVNRVNQCFPF-ETSSYFIGVLDIAGFEYFEHNS 467
VEQ +NA ALAK VY +F +V R+NQ + YFIGVLDIAGFE F+ NS
Sbjct: 420 ----VEQVSNAVGALAKAVYEKMFLWMVARINQQLDTKQPRQYFIGVLDIAGFEIFDFNS 475
Query: 468 FEQFCINYCNEKLQQFFNERILKEEQELYQKEGLGVNEVHY-VDNQDCIDLIEAKLVGIL 526
EQ CIN+ NEKLQQFFN + EQE Y+KEG+ + + +D CI+LIE K +GI
Sbjct: 476 LEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIE-KPMGIF 534
Query: 527 DILDEENRLPQPSDQHFTSAVHQKH---KDHFRLTIPRKSKLAVHRNIRDDEGFIIRHFA 583
IL+EE P+ +D F + ++ +H +F+ K K H F + H+A
Sbjct: 535 SILEEECMFPKATDTSFKNKLYDQHLGKSANFQKPKVVKGKAEAH--------FALIHYA 586
Query: 584 GAVCYETTQFVEKNNDALHMSLESLICESRDKFIRELF--------ESSTNNNKDTKQKA 635
G V Y T ++EKN D L+ ++ L +S K + +LF E + K +K
Sbjct: 587 GVVDYNITGWLEKNKDPLNETVVGLYQKSAMKTLAQLFSGAQTAEGEGAGGGAKKGGKKK 646
Query: 636 GKLSFISVGNKFKTQLNLLLDKLRSTGASFIRCIKPNLKMTSHHFEGAQILSQLQCSGMV 695
G SF +V F+ LN L+ LRST F+RCI PN T E +L QL+C+G++
Sbjct: 647 GS-SFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVL 705
Query: 696 SVLDLMQGGYPSRASFHELYNMYKKYMPDKLAR---LDPRLFCKALFKALGLNENDYKFG 752
+ + + G+PSR + + YK + +D + + L ++ ++ YKFG
Sbjct: 706 EGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFG 765
Query: 753 LTKVFFRPGKFAEFDQIMKSDPDHLAELVKRVNHWLTCSRWKKVQWCSLSVIKLKNKIKY 812
TKVFF+ G +++ D LA+L+ R C + L+ ++ + ++
Sbjct: 766 HTKVFFKAGLLGLLEEMR---DDKLAQLITRTQ--ARCRGF-------LARVEYQRMVE- 812
Query: 813 RAEACIKMQKTIRMWLCKRRHKP------RIDGLVKVGTLKKRLDKFNEVVSVLKDGKPE 866
R EA +Q IR ++ +H P +I L+K +K + E +KD +
Sbjct: 813 RREAIFCIQYNIRSFM-NVKHWPWMKLFFKIKPLLKSAETEKEMATMKEEFQKIKDELAK 871
Query: 867 MNKQIKNLEISIDTLMAKIKSTMMTQEQIQKEYDALVKSSEELLSALQKKKQQE------ 920
+ K LE + TL +K Q Q+Q E + L + E ++ K Q E
Sbjct: 872 SEAKRKELEEKMVTL---LKEKNDLQLQVQAEAEGLADAEERCDQLIKTKIQLEAKIKEV 928
Query: 921 -EEAERLRRIQEEMEKERKRREEDEKRRRKEEEERRMKLEMEAKRKQEEEERKKREDDEK 979
E AE I E+ ++++ E++ +K+ ++ + L K K E + K +E
Sbjct: 929 TERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEM 988
Query: 980 RIQAEVEAQLARQKE--EESQQQAVLE-QERRDRELALRIAQSEAELISDEAQADLALR- 1035
E A+L ++K+ +E+ QQ + + Q D+ L A+ + E D+ + L
Sbjct: 989 AGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEK 1048
Query: 1036 --RNDGTRPKMTPE---QMAKEMSEFLSRGPAVLATKAAAGTKKYDLSKWKYAELRDT-- 1088
R D R K E ++A+E + L K K++++S + +++ D
Sbjct: 1049 KLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLK--KKEFEISNLQ-SKIEDEQA 1105
Query: 1089 --INTSCDIELLAACREEFHRRLKVYHAWKSKNKKRNTE 1125
I I+ L A EE ++ A ++K +K+ ++
Sbjct: 1106 LGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSD 1144
Score = 70.5 bits (171), Expect = 1e-11
Identities = 69/266 (25%), Positives = 125/266 (46%), Gaps = 26/266 (9%)
Query: 795 KVQWCSLSVIKLKNKIKYRAEACIKMQKTIRMWLCKRRHKPRIDGLVKVGTLKKRLDKFN 854
KV + + IKL+ ++ E ++ +K +RM L R K +++G +K+
Sbjct: 1022 KVNTLTKAKIKLEQQVD-DLEGSLEQEKKLRMDL--ERAKRKLEGDLKLA---------Q 1069
Query: 855 EVVSVLKDGKPEMNKQIKNLEISIDTLMAKIKSTMMTQEQIQKEYDALVKSSEELLSALQ 914
E + +++ K ++++++K E I L +KI+ Q+QK+ L EEL
Sbjct: 1070 ESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEEL----- 1124
Query: 915 KKKQQEEEAERLRRIQEEMEKERKRREEDEKRRRKEEEERRMKLEMEAKRKQEEEERKKR 974
++E EAER R + E ++ RE +E R EE ++E +K+E E +K R
Sbjct: 1125 ---EEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMR 1181
Query: 975 ED-DEKRIQAEVEAQLARQKEEESQQQAVLEQERRDR-ELALRIAQSEAELISDEAQADL 1032
D +E +Q E A R+K +S + + + R + L +SE ++ D DL
Sbjct: 1182 RDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEID----DL 1237
Query: 1033 ALRRNDGTRPKMTPEQMAKEMSEFLS 1058
A ++ K E+M + + + LS
Sbjct: 1238 ASNVETVSKAKGNLEKMCRTLEDQLS 1263
Score = 48.5 bits (114), Expect = 4e-05
Identities = 42/150 (28%), Positives = 78/150 (52%), Gaps = 9/150 (6%)
Query: 883 AKIKSTMMTQEQIQKEYDALVKSSEELLSALQKKKQQEEEAERLRRIQEEMEKERKRREE 942
A ++ EQ K+ + +E+L KK+ Q+ EA R+R ++ E+E E+KR E
Sbjct: 1783 AHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEA-RVRELEGEVESEQKRNAE 1841
Query: 943 DEKRRRKEEEERRMKLEMEAKRKQEEEERKKREDDEKRIQAEVEAQLARQKEEESQQQAV 1002
K RK ERR+K E+ + +++ + + +D ++QA+V++ + +E E Q
Sbjct: 1842 AVKGLRK--HERRVK-ELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTN 1898
Query: 1003 LEQERRDRELALRIAQSEAELISDEAQADL 1032
L + R+ L+ EAE +D A++ +
Sbjct: 1899 LAKFRK-----LQHELEEAEERADIAESQV 1923
Score = 44.7 bits (104), Expect = 6e-04
Identities = 63/302 (20%), Positives = 135/302 (44%), Gaps = 30/302 (9%)
Query: 846 LKKRLDKFNEVVSVLKDGKPEMNKQIKNLEI---SIDTLMAKIKS----TMMTQEQIQKE 898
L K+ F+++++ K E + +++ + S+ T + KIK+ ++ E +++E
Sbjct: 1448 LDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRE 1507
Query: 899 YDALVKSSEELLSALQKKKQQEEEAERLRRIQEEMEKERKRREEDEKRRRKEEEERRMKL 958
L + +L + + ++ E E++++ E+ + E + E+ + + EE + +++
Sbjct: 1508 NKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRI 1567
Query: 959 EMEAKRKQEEEERKKREDDEKRIQAEVEAQLARQKEEESQQQAVLEQERRDRELALRIAQ 1018
++E + + E +RK E DE E++ Q+ L+ E R R A+R+ +
Sbjct: 1568 QLELNQVKSEVDRKIAEKDE-----EIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKK 1622
Query: 1019 S-EAELISDEAQADLALR-RNDGTRPKMTPEQMAKEMSEFLS---RGPAVLATKAAAGTK 1073
E +L E Q + A R + R + + K+ L R L + A +
Sbjct: 1623 KMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVER 1682
Query: 1074 KYDLSKWKYAELRDTINTS------CDIELLAACREEFHRRLKVYHAWKSK--NKKRNTE 1125
+ +L + + ELR T+ + + ELL A R+++ H + N K+ E
Sbjct: 1683 RANLLQAEIEELRATLEQTERSRKIAEQELLDA-----SERVQLLHTQNTSLINTKKKLE 1737
Query: 1126 TE 1127
T+
Sbjct: 1738 TD 1739
Score = 42.7 bits (99), Expect = 0.002
Identities = 63/341 (18%), Positives = 129/341 (37%), Gaps = 27/341 (7%)
Query: 846 LKKRLDKFNEVVSVLKDGKPEMNKQIKNLEISIDTLMAKIKSTMMTQEQIQKEYDALVKS 905
+K +D V + K + K + LE + L +K + + + L
Sbjct: 1230 MKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTE 1289
Query: 906 SEELLSALQKKKQQEEEAERLRRIQEEMEKERKRREEDEKRRRK--EEEERRMKLEMEAK 963
S E L +K+ + R ++ + +E KR+ E+E + + + + + +
Sbjct: 1290 SGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLL 1349
Query: 964 RKQEEEERKKREDDEKRI-QAEVEAQLARQKEEESQQQAVLEQERRDRELALRIAQSEAE 1022
R+Q EEE++ + + ++ + +A E R K E Q E E ++LA R+ +E
Sbjct: 1350 REQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEH 1409
Query: 1023 LISDEAQADLALRRNDGTRPKMTPEQMAKEMSEFLSRGPAVLATKAAAGTKKYD----LS 1078
+ + A+ + T +++ E+ + + A AA K+ + L+
Sbjct: 1410 VEAVNAKC---------ASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILA 1460
Query: 1079 KWK------YAELRDTINTSCDIEL-LAACREEFHRRLKVYHAWKSKNKKRNTE----TE 1127
+WK +AEL + + + L + + L K +NK E TE
Sbjct: 1461 EWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTE 1520
Query: 1128 QRAPKSVTDYDFAPFLNNSPQQNPAAQIPARQREIEMNRQQ 1168
Q A ++ Q+ Q + E + ++
Sbjct: 1521 QIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEE 1561
Score = 39.3 bits (90), Expect = 0.025
Identities = 32/190 (16%), Positives = 84/190 (44%), Gaps = 15/190 (7%)
Query: 854 NEVVSVLKDGKPEMNKQIKNLEISIDTLMAKIKSTMMTQEQIQKEYDALVKSSEELLSAL 913
+E V +L + K LE I + +++ + +++ + + + L
Sbjct: 1716 SERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEEL 1775
Query: 914 QKKKQQEEEAERLRRIQEEMEKERKRREEDEKR----------RRKEEEERRMKLEMEAK 963
+K++ ER+++ E+ K+ + R ++ ++ ++ E R ++ E+E++
Sbjct: 1776 KKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESE 1835
Query: 964 RKQEEEERKKREDDEKRIQAEVEAQLARQKEEESQQQAVLEQERRDRELALRIAQSEAEL 1023
+K+ E K E+R++ +L Q EE+ + L+ + ++ + +AE
Sbjct: 1836 QKRNAEAVKGLRKHERRVK-----ELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEE 1890
Query: 1024 ISDEAQADLA 1033
+++ +LA
Sbjct: 1891 AEEQSNTNLA 1900
Score = 38.9 bits (89), Expect = 0.032
Identities = 46/175 (26%), Positives = 80/175 (45%), Gaps = 21/175 (12%)
Query: 832 RHKPRIDGLVKVGTLKKRLDKFNEVVSVLKDGKPEMNKQIKNLEISIDTLMAKIKSTMMT 891
R K ++ VK L+ RLD+ ++ LK GK KQI+ LE + L +++S
Sbjct: 1787 RMKKNMEQTVK--DLQLRLDEAEQLA--LKGGK----KQIQKLEARVRELEGEVESEQKR 1838
Query: 892 QEQIQKEYDALVKSSEELLSALQKKKQQEEEAERLRRIQEEMEKERKRREEDEKRRRKE- 950
+ K + +EL Q EE+ + + R+Q+ ++K + + + KR+ +E
Sbjct: 1839 NAEAVKGLRKHERRVKELTY------QTEEDRKNILRLQDLVDK-LQAKVKSYKRQAEEA 1891
Query: 951 EEERRMKLEMEAKRKQEEEERKKREDDEKRIQAEVEAQLARQKEEESQQQAVLEQ 1005
EE+ L K + E EE ++R D AE + R K E + + E+
Sbjct: 1892 EEQSNTNLAKFRKLQHELEEAEERAD-----IAESQVNKLRVKSREVHTKVISEE 1941
>gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]
Length = 2003
Score = 453 bits (1165), Expect = e-127
Identities = 362/1216 (29%), Positives = 590/1216 (48%), Gaps = 178/1216 (14%)
Query: 7 VWAPHPTDGFQMGNIVDIGPDSLTIEPLNQKGKTFLALINQVFPAEEDSKKDVEDNCSLM 66
VW P GF+ + D G + +E L + G+ +Q+ ED L
Sbjct: 56 VWVPSELHGFEAAALRDEGEEEAEVE-LAESGRRLRLPRDQIQRMNPPKFSKAEDMAELT 114
Query: 67 YLNEATLLHNIKVRYSKDRIYTYVANILIAVNPYFDIPKIYSSEAIKSYQGKSLGTRPPH 126
LNEA++LHN++ RY IYTY + +NPY +P IY+ ++ Y+GK PPH
Sbjct: 115 CLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLP-IYTEAIVEMYRGKKRHEVPPH 173
Query: 127 VFAIADKAFRDMKVLKMSQSIIVSGESGAGKTENTKFVLRYL------------------ 168
V+A+ + A+R M + QSI+ +GESGAGKTENTK V++YL
Sbjct: 174 VYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVPAS 233
Query: 169 --TESYGTGQDIDDRIVEANPLLEAFGNAKTVRNNNSSRFGKFVEIHFNEKSSVVGGFVS 226
T SYG +++ ++++ANP+LEAFGNAKTV+N+NSSRFGKF+ I+F+ +VG +
Sbjct: 234 VSTVSYG---ELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIE 290
Query: 227 HYLLEKSRICVQGKEERNYHIFYRLCAGASEDIREKLHLSSPDNFRYLNRGCTRYFANKE 286
YLLEKSR Q K+E ++HIFY+L GA E ++ L L ++R+L G + ++
Sbjct: 291 TYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPS---SSPG 347
Query: 287 TDKQILQNRKSPEYLKAGSMKDPLLDDHGDFIRMCTAMKKIGLDDEEKLDLFRVVAGVLH 346
++++ Q +++ +G EE + + R+V+ VL
Sbjct: 348 QERELFQETLE-------------------------SLRVLGFSHEEIISMLRMVSAVLQ 382
Query: 347 LGNIDFEEAGSTSGGCNLKNKSAQSLEYCAELLGLDQDDL-RVSLTTRVMLTTAGGTKGT 405
GNI + +T N +AQ L LLGL D R LT R+ + +
Sbjct: 383 FGNIALKRERNTDQATMPDNTAAQKL---CRLLGLGVTDFSRALLTPRIKVG-----RDY 434
Query: 406 VIKVPLKVEQANNARDALAKTVYSHLFDHVVNRVNQCF---PFETSSYFIGVLDIAGFEY 462
V K K EQA+ A +ALAK Y LF +V R+N+ P + +S F+G+LDIAGFE
Sbjct: 435 VQKAQTK-EQADFALEALAKATYERLFRWLVLRLNRALDRSPRQGAS-FLGILDIAGFEI 492
Query: 463 FEHNSFEQFCINYCNEKLQQFFNERILKEEQELYQKEGLGVNEVHY-VDNQDCIDLIE-- 519
F+ NSFEQ CINY NEKLQQ FN + EQE YQ+EG+ + + +D Q CIDLIE
Sbjct: 493 FQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGLDLQPCIDLIERP 552
Query: 520 AKLVGILDILDEENRLPQPSDQHFTSAVHQKHKDHFRLTIPRKSKLAVHRNIRDDEGFII 579
A G+L +LDEE P+ +D+ F V Q+ H + P R++RD F +
Sbjct: 553 ANPPGLLALLDEECWFPKATDKSFVEKVAQEQGGHPKFQRP--------RHLRDQADFSV 604
Query: 580 RHFAGAVCYETTQFVEKNNDALHMSLESLICESRDKFIRELFES----------STNNNK 629
H+AG V Y+ +++ KN D L+ ++ +L+ +S D+ E+++ S+ +
Sbjct: 605 LHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKDVEGIVGLEQVSSLGDG 664
Query: 630 DTKQKAGKLSFISVGNKFKTQLNLLLDKLRSTGASFIRCIKPNLKMTSHHFEGAQILSQL 689
+ + F +VG +K L+ L+ L +T SF+RCI PN + + E +L QL
Sbjct: 665 PPGGRPRRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQL 724
Query: 690 QCSGMVSVLDLMQGGYPSRASFHELYNMYKKYMPDKLAR--LDPRLFCKALFKALGLNEN 747
+C+G++ + + + G+P+R F E Y+ P+ + + +D + C+ + +AL L+ N
Sbjct: 725 RCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKGFMDGKQACEKMIQALELDPN 784
Query: 748 DYKFGLTKVFFRPGKFAEFDQ-------------------------IMKSDPDHLAELVK 782
Y+ G +K+FFR G A+ ++ K A V
Sbjct: 785 LYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVM 844
Query: 783 RVN--------HWLTCSRWKKVQWCSLSVIKLKNKIKYRAEACIKMQKTIRMWLCKRRHK 834
+ N HW + KV+ L V + ++ RA+ ++QK + R
Sbjct: 845 QRNCAAYLKLRHWQWWRLFTKVK-PLLQVTRQDEVLQARAQ---ELQKVQELQQQSAREV 900
Query: 835 PRIDGLV-----KVGTLKKRLDKFNEVVSVLKDGKPEMNKQIKNLEISIDTLMAKIKSTM 889
+ G V + L ++L E+ + ++ + + + + LE+ + L A++
Sbjct: 901 GELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEE 960
Query: 890 MTQEQIQKEYDALVKSSEELLSALQ------------------KKKQQEEEAERLRRIQE 931
Q+Q E L + +EL + L+ K K+ EE+ L
Sbjct: 961 ECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNS 1020
Query: 932 EMEKERKRREE---DEKRRRKEEEER-----RMKLEMEAKRKQEEEERKKREDDEKRIQA 983
++ KERK E+ + + EEEE+ +++L+ EA E+ +K E + ++
Sbjct: 1021 KLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELE- 1079
Query: 984 EVEAQLARQKEEESQ--QQAVLEQERRDRELALRIAQSEAELISDEAQADLALRRNDGTR 1041
+L R+ + ES Q+ ++EQ++R EL ++ + E EL QA LA ++G
Sbjct: 1080 ----KLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEEL-----QAALARAEDEGGA 1130
Query: 1042 PKMTPEQMAKEMSEFLSRGPAVLATKAAAGTK----KYDLSKWKYA---ELRDTINTSCD 1094
+ + +E L+ L ++ A TK + DL + A EL DT++++
Sbjct: 1131 RAQLLKSL-REAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNA 1189
Query: 1095 IELLAACREEFHRRLK 1110
+ L + RE+ LK
Sbjct: 1190 QQELRSKREQEVTELK 1205
Score = 57.8 bits (138), Expect = 7e-08
Identities = 59/222 (26%), Positives = 117/222 (52%), Gaps = 29/222 (13%)
Query: 845 TLKKRLDKFNEVVSVLKDGKPEMNKQIKNLE---ISIDTLMAKIKSTMMTQEQIQKEYDA 901
T + ++ KF E + +L+D +++K+ K LE + A+ + + + +++ +Y+A
Sbjct: 1000 TTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEA 1059
Query: 902 LVKSSEELLSALQKKKQQEEEAERLRR--------IQEEMEKERKRREEDEKRRRKEEEE 953
+ E+ L+K+++ +E E+L+R +QE+M ++++R EE + ++EEE
Sbjct: 1060 TIADMED---RLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEE 1116
Query: 954 RRMKLEMEAKRKQEEEERKKREDDEKRIQAEVEAQLARQKEE-ESQQQAVLEQERRDREL 1012
++A + E+E R K ++ E +A LA +E+ ES++ A + E++ R+L
Sbjct: 1117 ------LQAALARAEDEGGARAQLLKSLR-EAQAALAEAQEDLESERVARTKAEKQRRDL 1169
Query: 1013 -----ALRIAQSEAELISDEAQADL-ALRRNDGTRPKMTPEQ 1048
ALR + E L S AQ +L + R + T K T E+
Sbjct: 1170 GEELEALR-GELEDTLDSTNAQQELRSKREQEVTELKKTLEE 1210
Score = 57.0 bits (136), Expect = 1e-07
Identities = 71/250 (28%), Positives = 111/250 (44%), Gaps = 44/250 (17%)
Query: 842 KVGTLKKRLDKFNEVVSVLKDG--KPEMNKQ-IKNLEISIDTLMAKIKSTMMTQEQIQKE 898
KV +L K K+ ++ ++D K E +Q ++ L+ +D ++++ M+ Q+Q +E
Sbjct: 1046 KVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEE 1105
Query: 899 YDA-LVKSSEELLSAL-----------QKKKQQEEEAERLRRIQEEMEKERKRREEDEKR 946
A L + EEL +AL Q K E L QE++E ER R + EK+
Sbjct: 1106 LRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQ 1165
Query: 947 RRKEEEE--------------RRMKLEMEAKRKQEEEERKKREDDEKRI-QAEVEAQLAR 991
RR EE + E+ +KR+QE E KK ++E RI +A V+ R
Sbjct: 1166 RRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQR 1225
Query: 992 QKEEESQQQAVLEQERRDR------ELALRIAQSE--AELISDEAQADLALRRNDGTRPK 1043
+ + LEQ RR + LAL SE AEL S L R +G + +
Sbjct: 1226 HGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSS------LQTARQEGEQRR 1279
Query: 1044 MTPEQMAKEM 1053
E +E+
Sbjct: 1280 RRLELQLQEV 1289
Score = 48.9 bits (115), Expect = 3e-05
Identities = 61/256 (23%), Positives = 117/256 (45%), Gaps = 50/256 (19%)
Query: 864 KPEMNKQIKNLEISIDTLMAKIKSTMMT---QEQI----QKEYDALVKSSEELL----SA 912
+ + KQ ++L ++ L +++ T+ + Q+++ ++E L K+ EE +A
Sbjct: 1159 RTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAA 1218
Query: 913 LQKKKQQEEEAERLRRIQEEMEKERKRREEDEKRR--------------------RKEEE 952
+Q+ +Q+ +A L + E++E+ R+ + EK R R+E E
Sbjct: 1219 VQELRQRHGQA--LGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGE 1276
Query: 953 ERRMKLEMEAKRKQEEEERKKREDDEKRIQAEVEAQLAR-QKEEESQQQAVLEQERRDRE 1011
+RR +LE++ +E + R D +R +AE +L R Q E E+ A+ E E +
Sbjct: 1277 QRRRRLELQL------QEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIR 1330
Query: 1012 LALRIAQSEA------ELISDEAQADLALRRNDGTRPKMTPEQMAKEMSEFLSRGPAVLA 1065
L+ ++ +EA EL+ +E +A LAL G+R + + A + A
Sbjct: 1331 LSKELSSTEAQLHDAQELLQEETRAKLAL----GSRVRAMEAEAAGLREQLEEEAAARER 1386
Query: 1066 TKAAAGTKKYDLSKWK 1081
T + LS+W+
Sbjct: 1387 AGRELQTAQAQLSEWR 1402
Score = 45.4 bits (106), Expect = 3e-04
Identities = 44/221 (19%), Positives = 97/221 (43%), Gaps = 34/221 (15%)
Query: 861 KDGKPEMNKQIKNLEISIDTLMA----------KIKSTMMTQEQIQKEYDALVKSSEELL 910
++ + E+ +Q + L ++ L++ +++ EQ + A V E+ L
Sbjct: 1521 QEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDEL 1580
Query: 911 SALQKKKQQEEEAERLRRIQEEMEKERKRREEDEKRRRKEEEERRMKLEMEAKRKQEE-- 968
+A + K + E + + Q E + + + +E+RR+ ++ R ++E + +RKQ
Sbjct: 1581 TAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLA 1640
Query: 969 -EERKKREDDEKRIQAEVEA--------------------QLARQKEEESQQQAVLEQER 1007
RKK E + + ++A++ + +L R+ EE + + +
Sbjct: 1641 VAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQN 1700
Query: 1008 RDRELALRIAQSEAELISDE-AQADLALRRNDGTRPKMTPE 1047
R+ E L+ ++E + +E A +D A R+ R +M E
Sbjct: 1701 RESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADE 1741
Score = 43.5 bits (101), Expect = 0.001
Identities = 51/263 (19%), Positives = 111/263 (42%), Gaps = 20/263 (7%)
Query: 834 KPRIDGLVKVGTLKKRLDKFNEVVSVLKDGKPEMNKQIKNLEISIDTLMAKIKSTMMTQE 893
+ R + K+ + L+ + ++ + ++K++ + E + ++ +
Sbjct: 1298 RARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKL 1357
Query: 894 QIQKEYDALVKSSEELLSALQKKKQQEEEAERLRRIQEEMEKERKRREEDEKRRRKEEEE 953
+ A+ + L L+++ E A R + + E +RR+E+E + EE
Sbjct: 1358 ALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEE 1417
Query: 954 RRMKLEMEA----KRKQEEEERKKR-EDDEKRIQAEVEAQLARQKEEESQQQAVLEQERR 1008
R + EA +R E+ E R E +R+Q E++ + E Q+Q V E++
Sbjct: 1418 ARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELD---DATMDLEQQRQLVSTLEKK 1474
Query: 1009 DRELALRIAQSEAEL---ISDEAQADLALRRNDGTRPKMT----PEQMAKEMSEFLSRG- 1060
R+ +A+ +A + + + +A+ R + +T EQ A+E E +R
Sbjct: 1475 QRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRAL 1534
Query: 1061 ----PAVLATKAAAGTKKYDLSK 1079
A+L++K G ++L +
Sbjct: 1535 RAELEALLSSKDDVGKSVHELER 1557
Score = 43.5 bits (101), Expect = 0.001
Identities = 50/239 (20%), Positives = 107/239 (44%), Gaps = 37/239 (15%)
Query: 846 LKKRLDKFNEVVSVLKDGKPEMNKQIKNLEISIDTLMAKIKSTMMTQEQIQKEYDALVKS 905
L+ L++ ++ GK E KQ++ ++ + L +++ T ++E+I + +
Sbjct: 1647 LEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQN----RE 1702
Query: 906 SEELLSALQKKKQQEEEAERLRRIQEEMEKERKRREEDEKRRRKEEE------------E 953
SE+ L L EAE LR +E +R RR+ + R +E E
Sbjct: 1703 SEKRLKGL--------EAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILE 1754
Query: 954 RRMKLE-----MEAKRKQEEEERKKREDDEKRIQAEVEA---QLARQKEEESQQQAVLEQ 1005
+ +LE +E + ++E+ + D +++ +VE+ +L+ ++ ++ ++ +Q
Sbjct: 1755 EKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQ 1814
Query: 1006 -ERRDRELALRIAQSEAELISDEAQADLALRRNDGTRPKMTPEQMAKEMSEFLSRGPAV 1063
ER+ +EL R+ + +A + AL ++ EQ+ +E E + G V
Sbjct: 1815 LERQIQELRGRLGEEDAGARARHKMTIAALE----SKLAQAEEQLEQETRERILSGKLV 1869
Score = 42.4 bits (98), Expect = 0.003
Identities = 52/222 (23%), Positives = 97/222 (43%), Gaps = 24/222 (10%)
Query: 855 EVVSVLKDGKPEMNKQIKNLEISIDTLMAKIKSTMMTQE---QIQKEYDALVKSSEE--- 908
E L+ G+ + + E L K ++ + ++Q+E D E+
Sbjct: 1407 EEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQ 1466
Query: 909 LLSALQKKKQQ------EEEAERLRRIQEEMEKERKRREEDEK-----RRRKEEEERRMK 957
L+S L+KK+++ EE+A LR ++E E + RE + + R +EE+E R +
Sbjct: 1467 LVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREE 1526
Query: 958 LEME--AKRKQEEEERKKREDDEKRI-QAEVEAQLARQKEEESQQQAV-LEQERRDRELA 1013
LE + A R + E ++D K + + E ++A Q + + Q LE E E A
Sbjct: 1527 LERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDA 1586
Query: 1014 LRIAQSEAELISDEAQADLALRRNDGTRPKMTPEQMAKEMSE 1055
+ + + + + DL R G + Q+AK++ +
Sbjct: 1587 KLRLEVTVQALKTQHERDLQGRDEAGEERR---RQLAKQLRD 1625
Score = 41.6 bits (96), Expect = 0.005
Identities = 57/244 (23%), Positives = 114/244 (46%), Gaps = 34/244 (13%)
Query: 834 KPRIDGLVKVGTLKKRLDKFNEVVSVLKDGKPEMNKQIKNL--EISID-TLMAKIKS-TM 889
K +++G ++G L++ L++ +L D ++ Q+++L E+S + + AK +S
Sbjct: 1756 KRQLEG--RLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQ 1813
Query: 890 MTQEQIQK------EYDALVKSSEEL-LSALQKKKQQEEEA------ERL------RRIQ 930
+ QIQ+ E DA ++ ++ ++AL+ K Q EE ER+ RR +
Sbjct: 1814 QLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAE 1873
Query: 931 EEMEK-----ERKRREEDEKRRRKEEEERRMKLEMEAKRKQEEEERKKREDDEKRIQAEV 985
+ +++ E +RR D+ R + E+ R+K +++ + ++ EEE + + +R+Q E+
Sbjct: 1874 KRLKEVVLQVEEERRVADQLRDQLEKGNLRVK-QLKRQLEEAEEEASRAQAGRRRLQREL 1932
Query: 986 EAQLARQKEEESQQQAVLEQERRDRELAL--RIAQSEAELISDEAQADLALRRNDGTRPK 1043
E + E +++ L R L R + L A + A G+ P
Sbjct: 1933 E-DVTESAESMNREVTTLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEEAQPGSGPS 1991
Query: 1044 MTPE 1047
PE
Sbjct: 1992 PEPE 1995
>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
sapiens]
Length = 1939
Score = 450 bits (1158), Expect = e-126
Identities = 325/1045 (31%), Positives = 521/1045 (49%), Gaps = 115/1045 (11%)
Query: 36 QKGKTFLALINQVFPAEEDSKKDVEDNCSLMYLNEATLLHNIKVRYSKDRIYTYVANILI 95
+ G T +QVFP +ED + +L+E +L+N+K RY+ IYTY +
Sbjct: 65 EAGATVTVKDDQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCV 124
Query: 96 AVNPYFDIPKIYSSEAIKSYQGKSLGTRPPHVFAIADKAFRDMKVLKMSQSIIVSGESGA 155
VNPY +P +Y++E + +Y+GK PPH+F+I+D A++ M + +QSI+++GESGA
Sbjct: 125 TVNPYKWLP-VYNAEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGA 183
Query: 156 GKTENTKFVLRYLTESYGTGQD-------------IDDRIVEANPLLEAFGNAKTVRNNN 202
GKT NTK V++Y TG+ ++D+I+ ANPLLEAFGNAKTVRN+N
Sbjct: 184 GKTVNTKRVIQYFATIAVTGEKKKEEVTSGKMQGTLEDQIISANPLLEAFGNAKTVRNDN 243
Query: 203 SSRFGKFVEIHFNEKSSVVGGFVSHYLLEKSRICVQGKEERNYHIFYRLCAGASEDIREK 262
SSRFGKF+ IHF + + YLLEKSR+ Q K ER+YHIFY++ + D+ E
Sbjct: 244 SSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQIMSNKKPDLIEM 303
Query: 263 LHLSSPDNFRYLNRGCTRYFANKETDKQILQNRKSPEYLKAGSMKDPLLDDHGDFIRMCT 322
L +++ N ++ G + P +DD + + +
Sbjct: 304 LLITT--------------------------NPYDYAFVSQGEITVPSIDDQEELMATDS 337
Query: 323 AMKKIGLDDEEKLDLFRVVAGVLHLGNIDFE----EAGSTSGGCNLKNKSAQSLEYCAEL 378
A++ +G +E++ ++++ V+H GN+ F+ E + G + +K+A L
Sbjct: 338 AIEILGFTSDERVSIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKAAY-------L 390
Query: 379 LGLDQDDLRVSLT-TRVMLTTAGGTKGTVIKVPLKVEQANNARDALAKTVYSHLFDHVVN 437
L+ DL +L RV + TKG V+Q NA ALAK VY +F +V
Sbjct: 391 QNLNSADLLKALCYPRVKVGNEYVTKGQT------VQQVYNAVGALAKAVYDKMFLWMVT 444
Query: 438 RVNQCFPF-ETSSYFIGVLDIAGFEYFEHNSFEQFCINYCNEKLQQFFNERILKEEQELY 496
R+NQ + YFIGVLDIAGFE F+ NS EQ CIN+ NEKLQQFFN + EQE Y
Sbjct: 445 RINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEY 504
Query: 497 QKEGLGVNEVHY-VDNQDCIDLIEAKLVGILDILDEENRLPQPSDQHFTSAVHQKH---K 552
+KEG+ + + +D CI+LIE K +GI IL+EE P+ +D F + ++++H
Sbjct: 505 KKEGIEWTFIDFGMDLAACIELIE-KPMGIFSILEEECMFPKATDTSFKNKLYEQHLGKS 563
Query: 553 DHFRLTIPRKSKLAVHRNIRDDEGFIIRHFAGAVCYETTQFVEKNNDALHMSLESLICES 612
++F+ P K K H F + H+AG V Y +++KN D L+ ++ L +S
Sbjct: 564 NNFQKPKPAKGKPEAH--------FSLIHYAGTVDYNIAGWLDKNKDPLNETVVGLYQKS 615
Query: 613 RDKFIRELFESSTNNNKDT--KQKAGK---LSFISVGNKFKTQLNLLLDKLRSTGASFIR 667
K + LF +T + +K GK SF +V F+ LN L+ LRST F+R
Sbjct: 616 AMKTLALLFVGATGAEAEAGGGKKGGKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVR 675
Query: 668 CIKPNLKMTSHHFEGAQILSQLQCSGMVSVLDLMQGGYPSRASFHELYNMYKKYMPDKLA 727
CI PN T E +L QL+C+G++ + + + G+PSR + + YK +
Sbjct: 676 CIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIP 735
Query: 728 R---LDPRLFCKALFKALGLNENDYKFGLTKVFFRPGKFAEFDQIMKSDPDHLAELVKRV 784
+D + + L ++ ++ YKFG TKVFF+ G +++ + LA+L+ R
Sbjct: 736 EGQFIDSKKASEKLLGSIDIDHTQYKFGHTKVFFKAGLLGLLEEMR---DEKLAQLITRT 792
Query: 785 NHWLTCSRWKKVQWCSLSVIKLK-NKIKYRAEACIKMQKTIRMWLCKRRHKP------RI 837
C + +++ K+ R E+ +Q +R ++ +H P +I
Sbjct: 793 Q-----------AMCRGFLARVEYQKMVERRESIFCIQYNVRAFM-NVKHWPWMKLYFKI 840
Query: 838 DGLVKVGTLKKRLDKFNEVVSVLKDGKPEMNKQIKNLEISIDTLMAKIKSTMMTQEQIQK 897
L+K +K + E K+ + + K LE + TLM + Q Q+Q
Sbjct: 841 KPLLKSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKND---LQLQVQA 897
Query: 898 EYDALVKSSEELLSALQKKKQQE-------EEAERLRRIQEEMEKERKRREEDEKRRRKE 950
E D+L + E ++ K Q E E AE I E+ ++++ E++ +K+
Sbjct: 898 EADSLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKD 957
Query: 951 EEERRMKLEMEAKRKQEEEERKKREDDEKRIQAEVEAQLARQKE--EESQQQAVLE-QER 1007
++ + L K K E + K +E E A+L ++K+ +E+ QQ + + Q
Sbjct: 958 IDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAE 1017
Query: 1008 RDRELALRIAQSEAELISDEAQADL 1032
D+ L A+ + E D+ + L
Sbjct: 1018 EDKVNTLTKAKIKLEQQVDDLEGSL 1042
Score = 69.7 bits (169), Expect = 2e-11
Identities = 69/266 (25%), Positives = 124/266 (46%), Gaps = 26/266 (9%)
Query: 795 KVQWCSLSVIKLKNKIKYRAEACIKMQKTIRMWLCKRRHKPRIDGLVKVGTLKKRLDKFN 854
KV + + IKL+ ++ E ++ +K IRM L R K +++G +K+
Sbjct: 1020 KVNTLTKAKIKLEQQVD-DLEGSLEQEKKIRMDL--ERAKRKLEGDLKLA---------Q 1067
Query: 855 EVVSVLKDGKPEMNKQIKNLEISIDTLMAKIKSTMMTQEQIQKEYDALVKSSEELLSALQ 914
E +++ K ++++++K E + L +KI+ Q+QK+ L EEL
Sbjct: 1068 ESTMDIENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEEL----- 1122
Query: 915 KKKQQEEEAERLRRIQEEMEKERKRREEDEKRRRKEEEERRMKLEMEAKRKQEEEERKKR 974
++E EAER R + E ++ RE +E R EE ++E +K+E E +K R
Sbjct: 1123 ---EEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMR 1179
Query: 975 ED-DEKRIQAEVEAQLARQKEEESQQQAVLEQERRDR-ELALRIAQSEAELISDEAQADL 1032
D +E +Q E A R+K +S + + + R + L +SE ++ D DL
Sbjct: 1180 RDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEID----DL 1235
Query: 1033 ALRRNDGTRPKMTPEQMAKEMSEFLS 1058
A ++ K E+M + + + LS
Sbjct: 1236 ASNMETVSKAKGNLEKMCRALEDQLS 1261
Score = 56.2 bits (134), Expect = 2e-07
Identities = 64/269 (23%), Positives = 122/269 (45%), Gaps = 30/269 (11%)
Query: 846 LKKRLDKFNEVVSVLKDGKPEMNKQIKNLEISIDTLMAKIKSTMMTQEQIQKEYDALVKS 905
LKK +D ++ ++ K ++KNL MA + T+ ++ KE AL ++
Sbjct: 954 LKKDIDDLELTLAKVEKEKHATENKVKNLTEE----MAGLDETIA---KLTKEKKALQEA 1006
Query: 906 SEELLSALQKKKQQEEEAERLRRIQEEMEKERKRREEDEKRRRKEEEERRMKLEMEAKRK 965
++ L LQ ++ + + + E+ + + E EK+ R + E + KLE + K
Sbjct: 1007 HQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDLKLA 1066
Query: 966 QE---EEERKKREDDEKRIQAEVEAQLARQKEEESQQQAVLEQERRDRELALRIAQSEAE 1022
QE + E K++ DEK + E E Q + E +Q ++ +++ +EL RI + E E
Sbjct: 1067 QESTMDIENDKQQLDEKLKKKEFEMS-GLQSKIEDEQALGMQLQKKIKELQARIEELEEE 1125
Query: 1023 LISDEA-QADLALRRNDGTRPKMTPEQMAKEMSEFLSRGPAVLATKAAAGTKKYDLSKWK 1081
+ ++ A +A +R+D +++E+ E R L A + + +++K +
Sbjct: 1126 IEAERASRAKAEKQRSD----------LSRELEEISER----LEEAGGATSAQIEMNKKR 1171
Query: 1082 YAEL----RDTINTSCDIELLAACREEFH 1106
AE RD + E AA + H
Sbjct: 1172 EAEFQKMRRDLEEATLQHEATAATLRKKH 1200
Score = 49.3 bits (116), Expect = 2e-05
Identities = 44/188 (23%), Positives = 91/188 (48%), Gaps = 20/188 (10%)
Query: 852 KFNEVVSVLKDGKPEMNKQIKNLEISIDTLMAKIKSTMMTQEQIQKEYDALVKSSEELLS 911
+ +++ ++ + + K I + + + L K + T E+++K + VK + L
Sbjct: 1744 EMEDIIQEARNAEEKAKKAITDAAMMAEELK-KEQDTSAHLERMKKNLEQTVKDLQHRLD 1802
Query: 912 ALQK------KKQQEEEAERLRRIQEEMEKERKRREEDEKRRRKEEEERRMKLEMEAKRK 965
++ KKQ ++ R+R ++ E+E E+KR E K RK ER++K E+ + +
Sbjct: 1803 EAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNVEAVKGLRK--HERKVK-ELTYQTE 1859
Query: 966 QEEEERKKREDDEKRIQAEVEAQLARQKEEESQQQAVLEQERRDRELALRIAQSEAELIS 1025
++ + + +D ++QA+V++ + +E E Q L + RR + EL
Sbjct: 1860 EDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNVNLSKFRR----------IQHELEE 1909
Query: 1026 DEAQADLA 1033
E +AD+A
Sbjct: 1910 AEERADIA 1917
Score = 47.4 bits (111), Expect = 9e-05
Identities = 63/302 (20%), Positives = 135/302 (44%), Gaps = 30/302 (9%)
Query: 846 LKKRLDKFNEVVSVLKDGKPEMNKQIKNLEI---SIDTLMAKIKS----TMMTQEQIQKE 898
L K+ F+++++ K E + +++ + S+ T + KIK+ ++ E +++E
Sbjct: 1446 LDKKQRNFDKILAEWKQKCEETHAELEASQKESRSLSTELFKIKNAYEESLDQLETLKRE 1505
Query: 899 YDALVKSSEELLSALQKKKQQEEEAERLRRIQEEMEKERKRREEDEKRRRKEEEERRMKL 958
L + +L + + ++ E E++++ E+ + E + E+ + + EE + +++
Sbjct: 1506 NKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKSELQAALEEAEASLEHEEGKILRI 1565
Query: 959 EMEAKRKQEEEERKKREDDEKRIQAEVEAQLARQKEEESQQQAVLEQERRDRELALRIAQ 1018
++E + + E +RK E DE E++ Q+ L+ E R R A+R+ +
Sbjct: 1566 QLELNQVKSEVDRKIAEKDE-----EIDQMKRNHIRIVESMQSTLDAEIRSRNDAIRLKK 1620
Query: 1019 S-EAELISDEAQADLALR-RNDGTRPKMTPEQMAKEMSEFLS---RGPAVLATKAAAGTK 1073
E +L E Q + A R + R + + K+ L R L + A +
Sbjct: 1621 KMEGDLNEMEIQLNHANRMAAEALRNYRNTQAILKDTQLHLDDALRSQEDLKEQLAMVER 1680
Query: 1074 KYDLSKWKYAELRDTINTS------CDIELLAACREEFHRRLKVYHAWKSK--NKKRNTE 1125
+ +L + + ELR T+ + + ELL A R+++ H + N K+ E
Sbjct: 1681 RANLLQAEIEELRATLEQTERSRKIAEQELLDA-----SERVQLLHTQNTSLINTKKKLE 1735
Query: 1126 TE 1127
T+
Sbjct: 1736 TD 1737
Score = 45.8 bits (107), Expect = 3e-04
Identities = 71/307 (23%), Positives = 130/307 (42%), Gaps = 41/307 (13%)
Query: 845 TLKKR----LDKFNEVVSVLKDGKPEMNKQIKNLEISIDTLMAKIKSTMMTQEQIQKEYD 900
TL+K+ + + E + L+ K ++ K+ +++ ID L + +++ + ++K
Sbjct: 1195 TLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCR 1254
Query: 901 ALVKSSEELLSALQKKKQQEEEAERL--------RRIQEEM-EKERKRREEDEKRRRKEE 951
AL E+ LS ++ K EEE +RL R+Q E E R+ E+D +
Sbjct: 1255 AL----EDQLSEIKTK---EEEQQRLINDLTAQRARLQTESGEYSRQLDEKDTLVSQLSR 1307
Query: 952 EERRMKLEMEAKRKQEEEERKKREDDEKRIQ-AEVEAQLARQKEEESQQQAVLEQERRDR 1010
++ ++E ++Q EEE K + +Q + + L R++ EE +Q+A E +R
Sbjct: 1308 GKQAFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQYEE-EQEAKAELQR--- 1363
Query: 1011 ELALRIAQSEAELISDEAQADLALRRNDGTRPKMTPEQMAKEMSEFLSRGPAVLATKAAA 1070
A+ A SE + + D R + K Q ++ E + A
Sbjct: 1364 --AMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVE----------AV 1411
Query: 1071 GTKKYDLSKWKYAELRDTINTSCDIELL-AACR--EEFHRRL-KVYHAWKSKNKKRNTET 1126
K L K K + + D+E AAC ++ R K+ WK K ++ + E
Sbjct: 1412 NAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAEL 1471
Query: 1127 EQRAPKS 1133
E +S
Sbjct: 1472 EASQKES 1478
Score = 40.8 bits (94), Expect = 0.008
Identities = 42/180 (23%), Positives = 81/180 (45%), Gaps = 19/180 (10%)
Query: 830 KRRHKPRIDGLVKVGTLKKRLDKFNEVVSVLKDGKPEMNK---QIKNLEISIDTLMAKIK 886
KR H ++ + TL + N+ + + K + ++N+ Q+ + + +
Sbjct: 1591 KRNHIRIVESMQS--TLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYR 1648
Query: 887 STMMTQEQIQKEYDALVKSSEELLSALQKKKQQEEEAERLRRIQEEMEKERKRREEDEKR 946
+T + Q D ++S E+L K+Q R +Q E+E+ R E+ E+
Sbjct: 1649 NTQAILKDTQLHLDDALRSQEDL------KEQLAMVERRANLLQAEIEELRATLEQTERS 1702
Query: 947 RRKEEEE-----RRMKLEMEAKRKQEEEERKKREDDEKRIQAEVE--AQLARQKEEESQQ 999
R+ E+E R++L + + +KK E D +IQ E+E Q AR EE++++
Sbjct: 1703 RKIAEQELLDASERVQL-LHTQNTSLINTKKKLETDISQIQGEMEDIIQEARNAEEKAKK 1761
Score = 35.0 bits (79), Expect = 0.46
Identities = 41/162 (25%), Positives = 72/162 (44%), Gaps = 32/162 (19%)
Query: 832 RHKPRIDGLVKVGTLKKRLDKFNEVVSVLKDGKPEMNK---QIKNLEISIDTLMA----- 883
R K ++ VK L+ RLD+ ++ LK GK ++ K +++ LE +++
Sbjct: 1785 RMKKNLEQTVK--DLQHRLDEAEQLA--LKGGKKQIQKLEARVRELEGEVESEQKRNVEA 1840
Query: 884 ---------KIKSTMMTQEQIQKEYDALVKSSEELLSALQKKKQQEEEAE--------RL 926
K+K E+ +K L ++L + ++ K+Q EEAE +
Sbjct: 1841 VKGLRKHERKVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNVNLSKF 1900
Query: 927 RRIQEEMEKERKRREEDEKRRRKEEEERRMKLEMEAKRKQEE 968
RRIQ E+E+ +R + E + K + R E+ K EE
Sbjct: 1901 RRIQHELEEAEERADIAESQVNKLRVKSR---EVHTKIISEE 1939
>gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo
sapiens]
Length = 1939
Score = 448 bits (1152), Expect = e-125
Identities = 347/1150 (30%), Positives = 564/1150 (49%), Gaps = 132/1150 (11%)
Query: 36 QKGKTFLALINQVFPAEEDSKKDVEDNCSLMYLNEATLLHNIKVRYSKDRIYTYVANILI 95
+ G T +QVF +ED + +L+E +L+N+K RY+ IYTY +
Sbjct: 65 EAGATVTVKEDQVFSMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCV 124
Query: 96 AVNPYFDIPKIYSSEAIKSYQGKSLGTRPPHVFAIADKAFRDMKVLKMSQSIIVSGESGA 155
VNPY +P +Y+ E + +Y+GK PPH+F+I+D A++ M + +QSI+++GESGA
Sbjct: 125 TVNPYKWLP-VYNPEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGA 183
Query: 156 GKTENTKFVLRYLTESYGTGQD-------------IDDRIVEANPLLEAFGNAKTVRNNN 202
GKT NTK V++Y TG+ ++D+I+ ANPLLEAFGNAKTVRN+N
Sbjct: 184 GKTVNTKRVIQYFATIAVTGEKKKEEPASGKMQGTLEDQIISANPLLEAFGNAKTVRNDN 243
Query: 203 SSRFGKFVEIHFNEKSSVVGGFVSHYLLEKSRICVQGKEERNYHIFYRLCAGASEDIREK 262
SSRFGKF+ IHF + + YLLEKSR+ Q K ER+YHIFY++ + ++ E
Sbjct: 244 SSRFGKFIRIHFGATGKLASADIETYLLEKSRVTFQLKAERSYHIFYQILSNKKPELIEM 303
Query: 263 LHLSS-PDNFRYLNRGCTRYFANKETDKQILQNRKSPEYLKAGSMKDPLLDDHGDFIRMC 321
L +++ P +F ++++G + P +DD + +
Sbjct: 304 LLITTNPYDFAFVSQG---------------------------EITVPSIDDQEELMATD 336
Query: 322 TAMKKIGLDDEEKLDLFRVVAGVLHLGNIDFE----EAGSTSGGCNLKNKSAQSLEYCAE 377
+A+ +G +EK+ ++++ V+H GN+ F+ E + G + +K+A
Sbjct: 337 SAVDILGFTADEKVAIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKAAY------- 389
Query: 378 LLGLDQDDLRVSLT-TRVMLTTAGGTKGTVIKVPLKVEQANNARDALAKTVYSHLFDHVV 436
L L+ DL SL RV + TKG V+Q NA ALAK +Y +F +V
Sbjct: 390 LTSLNSADLLKSLCYPRVKVGNEFVTKGQT------VQQVYNAVGALAKAIYEKMFLWMV 443
Query: 437 NRVNQCFPF-ETSSYFIGVLDIAGFEYFEHNSFEQFCINYCNEKLQQFFNERILKEEQEL 495
R+NQ + YFIGVLDIAGFE F+ NS EQ CIN+ NEKLQQFFN + EQE
Sbjct: 444 TRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEE 503
Query: 496 YQKEGLGVNEVHY-VDNQDCIDLIEAKLVGILDILDEENRLPQPSDQHFTSAVHQKH--- 551
Y+KEG+ + + +D CI+LIE K +GI IL+EE P+ +D F + ++++H
Sbjct: 504 YKKEGIEWEFIDFGMDLAACIELIE-KPMGIFSILEEECMFPKATDTSFKNKLYEQHLGK 562
Query: 552 KDHFRLTIPRKSKLAVHRNIRDDEGFIIRHFAGAVCYETTQFVEKNNDALHMSLESLICE 611
++F+ P K K H F + H+AG V Y +++KN D L+ ++ L +
Sbjct: 563 SNNFQKPKPAKGKPEAH--------FSLVHYAGTVDYNIAGWLDKNKDPLNETVVGLYQK 614
Query: 612 SRDKFIRELF------ESSTNNNKDTKQKAGKLSFISVGNKFKTQLNLLLDKLRSTGASF 665
S K + LF E+ K +K G SF +V F+ LN L+ LRST F
Sbjct: 615 SAMKTLAFLFSGAQTAEAEGGGGKKGGKKKGS-SFQTVSALFRENLNKLMTNLRSTHPHF 673
Query: 666 IRCIKPNLKMTSHHFEGAQILSQLQCSGMVSVLDLMQGGYPSRASFHELYNMYKKYMPDK 725
+RCI PN T E +L QL+C+G++ + + + G+PSR + + YK
Sbjct: 674 VRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASA 733
Query: 726 LAR---LDPRLFCKALFKALGLNENDYKFGLTKVFFRPGKFAEFDQIMKSDPDHLAELVK 782
+ +D + + L ++ ++ YKFG TKVFF+ G +++ + LA+L+
Sbjct: 734 IPEGQFIDSKKASEKLLGSIEIDHTQYKFGHTKVFFKAGLLGTLEEMR---DEKLAQLIT 790
Query: 783 RVNHWLTCSRWKKVQWCSLSVIKLK-NKIKYRAEACIKMQKTIRMWLCKRRHKP------ 835
R C +++++ K+ R E+ +Q IR ++ +H P
Sbjct: 791 RTQ-----------AICRGFLMRVEFRKMMERRESIFCIQYNIRAFM-NVKHWPWMKLYF 838
Query: 836 RIDGLVKVGTLKKRLDKFNEVVSVLKDGKPEMNKQIKNLEISIDTLMAKIKSTMMTQEQI 895
+I L+K +K + E K+ + + K LE + TLM + Q Q+
Sbjct: 839 KIKPLLKSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKND---LQLQV 895
Query: 896 QKEYDALVKSSEELLSALQKKKQQE-------EEAERLRRIQEEMEKERKRREEDEKRRR 948
Q E DAL + E ++ K Q E E AE I E+ ++++ E++ +
Sbjct: 896 QAEADALADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELK 955
Query: 949 KEEEERRMKLEMEAKRKQEEEERKKREDDEKRIQAEVEAQLARQKE--EESQQQAVLE-Q 1005
K+ ++ + L K K E + K +E E A+L ++K+ +E+ QQ + + Q
Sbjct: 956 KDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQ 1015
Query: 1006 ERRDRELALRIAQSEAELISDEAQADLALRRN---DGTRPKMTPE---QMAKEMSEFLSR 1059
D+ L A+++ E D+ + L + D R K E ++A+E +
Sbjct: 1016 MEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQESTMDTEN 1075
Query: 1060 GPAVLATKAAAGTKKYDLSKWKYAELRD----TINTSCDIELLAACREEFHRRLKVYHAW 1115
L K K++++S + ++ D I I+ L A EE ++ A
Sbjct: 1076 DKQQLNEKLK--KKEFEMSNLQ-GKIEDEQALAIQLQKKIKELQARIEELEEEIEAERAS 1132
Query: 1116 KSKNKKRNTE 1125
++K +K+ ++
Sbjct: 1133 RAKAEKQRSD 1142
Score = 66.6 bits (161), Expect = 1e-10
Identities = 66/261 (25%), Positives = 123/261 (47%), Gaps = 26/261 (9%)
Query: 802 SVIKLKNKIKYRA---EACIKMQKTIRMWLCKRRHKPRIDGLVKVGTLKKRLDKFNEVVS 858
++ K K K++ + E ++ +K + M L R K +++G +K+ + +D N+
Sbjct: 1023 TLTKAKTKLEQQVDDLEGSLEQEKKLCMDL--ERAKRKLEGDLKLAQ-ESTMDTEND--- 1076
Query: 859 VLKDGKPEMNKQIKNLEISIDTLMAKIKSTMMTQEQIQKEYDALVKSSEELLSALQKKKQ 918
K ++N+++K E + L KI+ Q+QK+ L EEL +
Sbjct: 1077 -----KQQLNEKLKKKEFEMSNLQGKIEDEQALAIQLQKKIKELQARIEEL--------E 1123
Query: 919 QEEEAERLRRIQEEMEKERKRREEDEKRRRKEEEERRMKLEMEAKRKQEEEERKKRED-D 977
+E EAER R + E ++ RE +E R EE ++E +K+E E +K R D +
Sbjct: 1124 EEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLE 1183
Query: 978 EKRIQAEVEAQLARQKEEESQQQAVLEQERRDRELALRIAQSEAELISDEAQADLALRRN 1037
E +Q E A R+K +S + + EQ + + ++ + ++EL + DLA
Sbjct: 1184 ESTLQHEATAAALRKKHADSVAE-LGEQIDSLQRVKQKLEKEKSELKME--INDLASNME 1240
Query: 1038 DGTRPKMTPEQMAKEMSEFLS 1058
++ K E+M + + + LS
Sbjct: 1241 TVSKAKANFEKMCRTLEDQLS 1261
Score = 45.8 bits (107), Expect = 3e-04
Identities = 64/302 (21%), Positives = 132/302 (43%), Gaps = 30/302 (9%)
Query: 846 LKKRLDKFNEVVSVLKDGKPEMNKQIKNLEI---SIDTLMAKIKSTMMTQ----EQIQKE 898
L K+ F++V++ K E +++ + S+ T + K+K+ E +++E
Sbjct: 1446 LDKKQRNFDKVLAEWKQKYEETQAELEASQKESRSLSTELFKVKNAYEESLDHLETLKRE 1505
Query: 899 YDALVKSSEELLSALQKKKQQEEEAERLRRIQEEMEKERKRREEDEKRRRKEEEERRMKL 958
L + +L + + + E E++++ + + E + E+ + + EE + +++
Sbjct: 1506 NKNLQQEISDLTEQIAEGGKHIHELEKVKKQLDHEKSELQTSLEEAEASLEHEEGKILRI 1565
Query: 959 EMEAKRKQEEEERKKREDDEKRIQAEVEAQLARQKEEESQQQAVLEQERRDRELALRIAQ 1018
++E + + E +RK E DE E++ Q+ L+ E R R ALRI +
Sbjct: 1566 QLELNQVKSEIDRKIAEKDE-----ELDQLKRNHLRVVESMQSTLDAEIRSRNDALRIKK 1620
Query: 1019 S-EAELISDEAQADLALRR-NDGTRPKMTPEQMAKEMSEFLS---RGPAVLATKAAAGTK 1073
E +L E Q + A R+ + R + + K+ L RG L + A +
Sbjct: 1621 KMEGDLNEMEIQLNHANRQAAEALRNLRNTQGILKDTQLHLDDAIRGQDDLKEQLAMVER 1680
Query: 1074 KYDLSKWKYAELRDTINTS------CDIELLAACREEFHRRLKVYHAWKSK--NKKRNTE 1125
+ +L + + ELR ++ + + ELL A R+++ H + N K+ E
Sbjct: 1681 RANLMQAEVEELRASLERTERGRKMAEQELLDA-----SERVQLLHTQNTSLINTKKKLE 1735
Query: 1126 TE 1127
T+
Sbjct: 1736 TD 1737
Score = 43.5 bits (101), Expect = 0.001
Identities = 44/174 (25%), Positives = 81/174 (46%), Gaps = 19/174 (10%)
Query: 832 RHKPRIDGLVKVGTLKKRLDKFNEVVSVLKDGKPEMNKQIKNLEISIDTLMAKIKSTMMT 891
R K ++ VK L+ RLD+ ++ LK GK KQI+ LE + L ++++S
Sbjct: 1785 RMKKNMEQTVK--DLQLRLDEAEQLA--LKGGK----KQIQKLEARVRELESEVESEQKH 1836
Query: 892 QEQIQKEYDALVKSSEELLSALQKKKQQEEEAERLRRIQEEMEKERKRREEDEKRRRKEE 951
+ K + +EL Q EE+ + + R+Q+ ++K + + + +++ + E
Sbjct: 1837 NVEAVKGLRKHERRVKELTY------QTEEDRKNILRLQDLVDKLQTKVKAYKRQAEEAE 1890
Query: 952 EERRMKLEMEAKRKQEEEERKKREDDEKRIQAEVEAQLARQKEEESQQQAVLEQ 1005
E+ + L K + E EE K+R D AE + R K E + + E+
Sbjct: 1891 EQSNVNLAKFRKLQHELEEAKERAD-----IAESQVNKLRVKSREVHTKVISEE 1939
Score = 39.7 bits (91), Expect = 0.019
Identities = 43/202 (21%), Positives = 80/202 (39%), Gaps = 24/202 (11%)
Query: 843 VGTLKKRLDKFNEVVSVLKDGKPEMNKQIKNLEISIDTL-----------------MAKI 885
V L +++D V L+ K E+ +I +L +++T+ +++I
Sbjct: 1204 VAELGEQIDSLQRVKQKLEKEKSELKMEINDLASNMETVSKAKANFEKMCRTLEDQLSEI 1263
Query: 886 KSTMMTQEQIQKEYDA----LVKSSEELLSALQKKKQQEEEAERLRRIQEEMEKERKRRE 941
K+ Q+++ E A L S E L +K + R ++ + +E KR+
Sbjct: 1264 KTKEEEQQRLINELSAQKARLHTESGEFSRQLDEKDAMVSQLSRGKQAFTQQIEELKRQL 1323
Query: 942 EDEKRRRKEEEERRMKLEMEA---KRKQEEEERKKREDDEKRIQAEVEAQLARQKEEESQ 998
E+E + + + + + EEE+ K E +A E R K E
Sbjct: 1324 EEETKAKSTLAHALQSARHDCDLLREQYEEEQEAKAELQRGMSKANSEVAQWRTKYETDA 1383
Query: 999 QQAVLEQERRDRELALRIAQSE 1020
Q E E ++LA R+ +E
Sbjct: 1384 IQRTEELEEAKKKLAQRLQDAE 1405
Score = 39.3 bits (90), Expect = 0.025
Identities = 37/180 (20%), Positives = 86/180 (47%), Gaps = 19/180 (10%)
Query: 868 NKQIKNLEISIDTLMAKIKSTM--MTQEQIQKEYDALVKSSEELLSALQKKKQQEEEA-- 923
N + N + ++T +++I+ M + QE E A ++ + A + KK+Q+ A
Sbjct: 1724 NTSLINTKKKLETDISQIQGEMEDIVQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHL 1783
Query: 924 ERLRRIQEEMEKERKRREEDEKR----------RRKEEEERRMKLEMEAKRKQEEEERKK 973
ER+++ E+ K+ + R ++ ++ ++ E R ++ E+E+++K E K
Sbjct: 1784 ERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELESEVESEQKHNVEAVKG 1843
Query: 974 REDDEKRIQAEVEAQLARQKEEESQQQAVLEQERRDRELALRIAQSEAELISDEAQADLA 1033
E+R++ +L Q EE+ + L+ + ++ + +AE +++ +LA
Sbjct: 1844 LRKHERRVK-----ELTYQTEEDRKNILRLQDLVDKLQTKVKAYKRQAEEAEEQSNVNLA 1898
>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
sapiens]
Length = 1935
Score = 443 bits (1140), Expect = e-124
Identities = 327/1071 (30%), Positives = 535/1071 (49%), Gaps = 110/1071 (10%)
Query: 5 KPVWAPHPTDGFQMGNIVDIGPDSLTIEPLNQKGKTFLALINQVFPAEEDSKKDVEDNCS 64
K V+ P F IV +T E + GKT +QV +ED
Sbjct: 35 KDVFVPDDKQEFVKAKIVSREGGKVTAE--TEYGKTVTVKEDQVMQQNPPKFDKIEDMAM 92
Query: 65 LMYLNEATLLHNIKVRYSKDRIYTYVANILIAVNPYFDIPKIYSSEAIKSYQGKSLGTRP 124
L +L+E +L+N+K RY IYTY + VNPY +P +Y+ E + +Y+GK P
Sbjct: 93 LTFLHEPAVLYNLKDRYGSWMIYTYSGLFCVTVNPYKWLP-VYTPEVVAAYRGKKRSEAP 151
Query: 125 PHVFAIADKAFRDMKVLKMSQSIIVSGESGAGKTENTKFVLRYLT------------ESY 172
PH+F+I+D A++ M + +QSI+++GESGAGKT NTK V++Y +S
Sbjct: 152 PHIFSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFAVIAAIGDRSKKDQSP 211
Query: 173 GTGQDIDDRIVEANPLLEAFGNAKTVRNNNSSRFGKFVEIHFNEKSSVVGGFVSHYLLEK 232
G G ++D+I++ANP LEAFGNAKTVRN+NSSRFGKF+ IHF + + YLLEK
Sbjct: 212 GKGT-LEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEK 270
Query: 233 SRICVQGKEERNYHIFYRLCAGASEDIREKLHLSS-PDNFRYLNRGCTRYFANKETDKQI 291
SR+ Q K ER+YHIFY++ + ++ + L +++ P ++ ++++G T +
Sbjct: 271 SRVIFQLKAERDYHIFYQILSNKKPELLDMLLITNNPYDYAFISQGETTVAS-------- 322
Query: 292 LQNRKSPEYLKAGSMKDPLLDDHGDFIRMCTAMKKIGLDDEEKLDLFRVVAGVLHLGNID 351
+DD + + A +G EEK ++++ ++H GN+
Sbjct: 323 -------------------IDDAEELMATDNAFDVLGFTSEEKNSMYKLTGAIMHFGNMK 363
Query: 352 FE----EAGSTSGGCNLKNKSAQSLEYCAELLGLDQDDLRVSLT-TRVMLTTAGGTKGTV 406
F+ E + G +KSA L+GL+ DL L RV + TKG
Sbjct: 364 FKLKQREEQAEPDGTEEADKSAY-------LMGLNSADLLKGLCHPRVKVGNEYVTKGQ- 415
Query: 407 IKVPLKVEQANNARDALAKTVYSHLFDHVVNRVNQCFPF-ETSSYFIGVLDIAGFEYFEH 465
V+Q A ALAK VY +F+ +V R+N + YFIGVLDIAGFE F+
Sbjct: 416 -----NVQQVIYATGALAKAVYERMFNWMVTRINATLETKQPRQYFIGVLDIAGFEIFDF 470
Query: 466 NSFEQFCINYCNEKLQQFFNERILKEEQELYQKEGLGVNEVHY-VDNQDCIDLIEAKLVG 524
NSFEQ CIN+ NEKLQQFFN + EQE Y+KEG+ + + +D Q CIDLIE K +G
Sbjct: 471 NSFEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLQACIDLIE-KPMG 529
Query: 525 ILDILDEENRLPQPSDQHFTSAVHQKHKDHFRLTIPRKSKLAVHRNI--RDDEGFIIRHF 582
I+ IL+EE P+ +D F + + H + + + RNI + + F + H+
Sbjct: 530 IMSILEEECMFPKATDMTFKAKLFDNH-------LGKSANFQKPRNIKGKPEAHFSLIHY 582
Query: 583 AGAVCYETTQFVEKNNDALHMSLESLICESRDKFIRELFESSTNNNKDTKQKAGKL---- 638
AG V Y +++KN D L+ ++ L +S K + LF + + ++ GK
Sbjct: 583 AGIVDYNIIGWLQKNKDPLNETVVGLYQKSSLKLLSTLFANYAGADAPIEKGKGKAKKGS 642
Query: 639 SFISVGNKFKTQLNLLLDKLRSTGASFIRCIKPNLKMTSHHFEGAQILSQLQCSGMVSVL 698
SF +V + LN L+ LRST F+RCI PN + + ++ QL+C+G++ +
Sbjct: 643 SFQTVSALHRENLNKLMTNLRSTHPHFVRCIIPNETKSPGVMDNPLVMHQLRCNGVLEGI 702
Query: 699 DLMQGGYPSRASFHELYNMYKKYMPDKLAR---LDPRLFCKALFKALGLNENDYKFGLTK 755
+ + G+P+R + + Y+ P + +D R + L +L ++ N YKFG TK
Sbjct: 703 RICRKGFPNRILYGDFRQRYRILNPAAIPEGQFIDSRKGAEKLLSSLDIDHNQYKFGHTK 762
Query: 756 VFFRPGKFAEFDQIMKSDPDHLAELVKRVNHW----LTCSRWKKVQWCSLSVIKLKNKIK 811
VFF+ G +++ + L+ ++ R+ L +KK+ S++ ++ I
Sbjct: 763 VFFKAGLLGLLEEMR---DERLSRIITRIQAQSRGVLARMEYKKLLERRDSLLVIQWNI- 818
Query: 812 YRAEACIKMQKTIRMWLCKRRHKPRIDGLVKVGTLKKRLDKFNEVVSVLKDGKPEMNKQI 871
RA +K ++++ +I L+K +K + E + LK+ + +
Sbjct: 819 -RAFMGVKNWPWMKLYF-------KIKPLLKSAEREKEMASMKEEFTRLKEALEKSEARR 870
Query: 872 KNLEISIDTLMAKIKSTMMTQEQIQKEYDALVKSSEELLSALQKKKQQEEEAERL-RRIQ 930
K LE + +++ ++ Q Q+Q E D L + E ++ K Q E + + + R++
Sbjct: 871 KELE---EKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLE 927
Query: 931 EEMEKE-----RKRREEDE-KRRRKEEEERRMKLEMEAKRKQEEEERKKREDDEKRIQAE 984
+E E +KR+ EDE +++ ++ + L K K E + K +E E
Sbjct: 928 DEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDE 987
Query: 985 VEAQLARQKE--EESQQQAVLE-QERRDRELALRIAQSEAELISDEAQADL 1032
+ A+L ++K+ +E+ QQA+ + Q D+ L A+ + E D+ + L
Sbjct: 988 IIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSL 1038
Score = 66.2 bits (160), Expect = 2e-10
Identities = 65/251 (25%), Positives = 120/251 (47%), Gaps = 34/251 (13%)
Query: 795 KVQWCSLSVIKLKNKIKYRAEACIKMQKTIRMWLCKRRHKPRIDGLVKVGTLKKRLDKFN 854
KV + + +KL+ ++ E ++ +K +RM L R K +++G +K+
Sbjct: 1016 KVNTLTKAKVKLEQQVD-DLEGSLEQEKKVRMDL--ERAKRKLEGDLKLT---------Q 1063
Query: 855 EVVSVLKDGKPEMNKQIKNLEISIDTLMAKIKSTMMTQEQIQKEYDALVKSSEELLSALQ 914
E + L++ K ++++++K + ++ L A+I+ Q+QK+ L EEL
Sbjct: 1064 ESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEEL----- 1118
Query: 915 KKKQQEEEAERLRRIQEEMEKERKRREEDEKRRRKEEEERRMKLEMEAKRKQEEEERKKR 974
++E EAER R + E + RE +E R EE +++E +K+E E +K R
Sbjct: 1119 ---EEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMR 1175
Query: 975 ED-DEKRIQAEVEAQLARQKEEES------------QQQAVLEQERRDRELALRIAQSEA 1021
D +E +Q E A R+K +S + + LE+E+ + +L L S
Sbjct: 1176 RDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNM 1235
Query: 1022 ELISDEAQADL 1032
E I +A+A+L
Sbjct: 1236 EQII-KAKANL 1245
Score = 54.7 bits (130), Expect = 6e-07
Identities = 81/376 (21%), Positives = 169/376 (44%), Gaps = 51/376 (13%)
Query: 762 KFAEFDQIMKSDPDHLAELVKRVNHWLTCSRWKKVQWCSLSVIKLKNKIKYRAEACIKMQ 821
K AE ++ M S + L + + + +R K+++ +S+++ KN ++ + +A +
Sbjct: 841 KSAEREKEMASMKEEFTRLKEALEK--SEARRKELEEKMVSLLQEKNDLQLQVQA-EQDN 897
Query: 822 KTIRMWLCKRRHKPRIDGLVKVGTLKKRLDKFNEVVSVLKDGKPEMNKQIKNLEISIDTL 881
C + K +I KV + +RL+ E+ + L K ++ + L+ ID L
Sbjct: 898 LADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDL 957
Query: 882 ---MAKIKSTMMTQEQIQKEYDALVKSSEELLSALQKKKQ---------------QEEEA 923
+AK++ E K + +E+++ L K+K+ +E++
Sbjct: 958 ELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKV 1017
Query: 924 ERLRRIQEEMEKERKRRE---EDEKRRRKEEEERRMKLEMEAKRKQE-----EEERKKRE 975
L + + ++E++ E E EK+ R + E + KLE + K QE E ++++ +
Sbjct: 1018 NTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLD 1077
Query: 976 DDEKRIQAEVEAQLARQKEEESQQQAVLEQERRDRELALRIAQSEAELISDE-AQADLAL 1034
+ K+ E+ A AR ++E++ + +++ +EL RI + E EL ++ A+A +
Sbjct: 1078 ERLKKKDFELNALNARIEDEQALGS---QLQKKLKELQARIEELEEELEAERTARAKVEK 1134
Query: 1035 RRNDGTRPKMTPEQMAKEMSEFLSRGPAVLATKAAAGTKKYDLSKWKYAEL----RDTIN 1090
R+D +++E+ E R L A + + +++K + AE RD
Sbjct: 1135 LRSD----------LSRELEEISER----LEEAGGATSVQIEMNKKREAEFQKMRRDLEE 1180
Query: 1091 TSCDIELLAACREEFH 1106
+ E AA + H
Sbjct: 1181 ATLQHEATAAALRKKH 1196
Score = 53.9 bits (128), Expect = 1e-06
Identities = 49/209 (23%), Positives = 99/209 (47%), Gaps = 19/209 (9%)
Query: 847 KKRLD--------KFNEVVSVLKDGKPEMNKQIKNLEISIDTLMAKIKSTMMTQEQIQKE 898
KK++D + E V ++ + + K I + + + L K + T E+++K
Sbjct: 1727 KKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELK-KEQDTSAHLERMKKN 1785
Query: 899 YDALVKSSEELLSALQK------KKQQEEEAERLRRIQEEMEKERKRREEDEKRRRKEEE 952
+ +K + L ++ KKQ ++ R+R ++ E+E E+KR E K RK
Sbjct: 1786 MEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRK--S 1843
Query: 953 ERRMKLEMEAKRKQEEEERKKREDDEKRIQAEVEAQLARQKEEESQQQAVLEQERRDREL 1012
ERR+K E+ + +++ + + +D ++Q +V+A + +E E Q L + R+ +
Sbjct: 1844 ERRIK-ELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQH- 1901
Query: 1013 ALRIAQSEAELISDEAQADLALRRNDGTR 1041
L A+ A++ + A R+ GT+
Sbjct: 1902 ELDEAEERADIAESQVNKLRAKSRDIGTK 1930
Score = 48.1 bits (113), Expect = 5e-05
Identities = 63/283 (22%), Positives = 116/283 (40%), Gaps = 46/283 (16%)
Query: 860 LKDGKPEMNKQIKNLEISIDTLMAKIKSTMMTQEQIQKEYDAL---VKSSEELLSALQKK 916
L++ K ++ ++++ E +++ + AK S T+ ++Q E + L V+ S +AL KK
Sbjct: 1386 LEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKK 1445
Query: 917 -----------KQQEEEAE--------RLRRIQEEMEKERKRREED------EKRRRKEE 951
KQ+ EE++ R + E+ K + EE KR K
Sbjct: 1446 QRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNL 1505
Query: 952 EERRMKL------------EMEAKRKQEEEERKKREDDEKRIQAEV---EAQLARQKEEE 996
+E L E+E RKQ E E+ + + + +A + E ++ R + E
Sbjct: 1506 QEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEF 1565
Query: 997 SQQQAVLEQERRDRELALRIAQSEAELISDEAQADL---ALRRNDGTRPKMTPEQMAKEM 1053
+Q +A +E++ +++ + A+ + D Q L RN+ R K E EM
Sbjct: 1566 NQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEM 1625
Query: 1054 SEFLSRGPAVLATKAAAGTKKYDLSKWKYAELRDTINTSCDIE 1096
LS + A L K +L D + + D++
Sbjct: 1626 EIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLK 1668
Score = 44.7 bits (104), Expect = 6e-04
Identities = 46/198 (23%), Positives = 88/198 (44%), Gaps = 13/198 (6%)
Query: 846 LKKRLDKFNEVVSVLKDGKPEMNKQIKNLEI---SIDTLMAKIKS----TMMTQEQIQKE 898
L K+ F+++++ K E ++++ + S+ T + K+K+ ++ E ++E
Sbjct: 1442 LDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRE 1501
Query: 899 YDALVKSSEELLSALQKKKQQEEEAERLRRIQEEMEKERKRREEDEKRRRKEEEERRMKL 958
L + +L L + E E++R+ E + E + E+ + + EE + ++
Sbjct: 1502 NKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRA 1561
Query: 959 EMEAKRKQEEEERKKREDDEKRIQAEVEAQLARQKEEESQQQAVLEQERRDRELALRIAQ 1018
++E + + E ERK E DE E+E Q L+ E R R ALR+ +
Sbjct: 1562 QLEFNQIKAEIERKLAEKDE-----EMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKK 1616
Query: 1019 S-EAELISDEAQADLALR 1035
E +L E Q A R
Sbjct: 1617 KMEGDLNEMEIQLSHANR 1634
Score = 44.7 bits (104), Expect = 6e-04
Identities = 57/250 (22%), Positives = 109/250 (43%), Gaps = 43/250 (17%)
Query: 808 NKIKYRAEACIKMQKTIRMWLCKRRHKPRIDGLVKVGTLKKRLDKFNEVVSVLKDGKPEM 867
N+IK E + +K M KR H +D L +L NE + V K + ++
Sbjct: 1566 NQIKAEIERKLA-EKDEEMEQAKRNHLRVVDSLQT--SLDAETRSRNEALRVKKKMEGDL 1622
Query: 868 NKQIKNLEISIDTLMA-----KIKSTMMTQEQIQKEYDALVKSSEELLSAL----QKKKQ 918
N+ +++S MA ++KS + Q + D V+++++L + ++
Sbjct: 1623 NEM--EIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNL 1680
Query: 919 QEEEAERLRRIQEEMEKERKRREEDEKRRRKEEEERRMKLEMEAKRKQEEEERKKREDDE 978
+ E E LR + E+ E+ RK E++ E R++L + ++ ++KK + D
Sbjct: 1681 LQAELEELRAVVEQTERSRKLAEQE-----LIETSERVQL-LHSQNTSLINQKKKMDADL 1734
Query: 979 KRIQAEVE--------------------AQLARQKEEESQQQAVLEQERRDRELALRIAQ 1018
++Q EVE A +A + ++E A LE+ +++ E ++ Q
Sbjct: 1735 SQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQ 1794
Query: 1019 ---SEAELIS 1025
EAE I+
Sbjct: 1795 HRLDEAEQIA 1804
Score = 42.7 bits (99), Expect = 0.002
Identities = 57/263 (21%), Positives = 106/263 (40%), Gaps = 27/263 (10%)
Query: 791 SRWKKVQWCSLSVIKLKNKIKYRAEACIKMQKTIRMWLCKRRHKPRIDGLVKVGTLKKRL 850
S K+ + S + KLKN + E ++ K + D ++G+ K +
Sbjct: 1469 SSQKEARSLSTELFKLKNAYEESLEHLETFKREN-----KNLQEEISDLTEQLGSSGKTI 1523
Query: 851 DKFNEVVSVLKDGKPEMNKQIKNLEISIDTLMAKIKSTMMTQEQIQKEYDALVKSSEE-- 908
+ +V L+ K E+ ++ E S++ KI + QI+ E + + +E
Sbjct: 1524 HELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEM 1583
Query: 909 -------------LLSALQKKKQQEEEAERLRRIQEEMEKERKRREEDEKRRRKEEEERR 955
L ++L + + EA R+++ E E + + R E +++
Sbjct: 1584 EQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQV 1643
Query: 956 MKLEMEAKRKQEE-EERKKREDDEKRIQAEVEAQLARQKEEESQQQAVLEQERRDRELAL 1014
L+ K Q + ++ + DD K A VE + + E + +AV+EQ R R+LA
Sbjct: 1644 KSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLA- 1702
Query: 1015 RIAQSEAELISDEAQADLALRRN 1037
E ELI + L +N
Sbjct: 1703 -----EQELIETSERVQLLHSQN 1720
Score = 39.3 bits (90), Expect = 0.025
Identities = 62/341 (18%), Positives = 131/341 (38%), Gaps = 29/341 (8%)
Query: 847 KKRLDKFNEVVSVLKDGKPEMNKQIKNLEISIDTLMAKIKSTMMTQEQIQKEYDALVKSS 906
K LD + + K + K + LE ++ +K + T + + + L +
Sbjct: 1225 KLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTEN 1284
Query: 907 EELLSALQKKKQQEEEAERLRRIQEEMEKERKRREEDEKRRRK--EEEERRMKLEMEAKR 964
EL L +K+ + R + + ++ KR+ E+E + + + + + + R
Sbjct: 1285 GELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLR 1344
Query: 965 KQEEEERKKREDDEKRI-QAEVEAQLARQKEEESQQQAVLEQERRDRELALRIAQSEAEL 1023
+Q EEE + + + ++ + +A E R K E Q E E ++LA R+ ++E +
Sbjct: 1345 EQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAV 1404
Query: 1024 ISDEAQADLALRRNDGTRPKMTPEQMAKEMSEFLSRGPAVLATKAAAGTKKYD----LSK 1079
+ A+ + + T ++ E+ + + A AA K+ + L++
Sbjct: 1405 EAVNAKC---------SSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAE 1455
Query: 1080 W--KYAELRDTINT------SCDIELLAACREEFHRRLKVYHAWKSKNKKRNTE----TE 1127
W KY E + + + S EL + + L+ +K +NK E TE
Sbjct: 1456 WKQKYEESQSELESSQKEARSLSTELF-KLKNAYEESLEHLETFKRENKNLQEEISDLTE 1514
Query: 1128 QRAPKSVTDYDFAPFLNNSPQQNPAAQIPARQREIEMNRQQ 1168
Q T ++ + Q + E + ++
Sbjct: 1515 QLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEE 1555
>gi|156104908 myosin heavy chain 6 [Homo sapiens]
Length = 1939
Score = 441 bits (1133), Expect = e-123
Identities = 316/1037 (30%), Positives = 518/1037 (49%), Gaps = 100/1037 (9%)
Query: 36 QKGKTFLALINQVFPAEEDSKKDVEDNCSLMYLNEATLLHNIKVRYSKDRIYTYVANILI 95
+ GKT +QV +ED L +L+E +L N+K RY+ IYTY +
Sbjct: 64 ENGKTVTVKEDQVLQQNPPKFDKIEDMAMLTFLHEPAVLFNLKERYAAWMIYTYSGLFCV 123
Query: 96 AVNPYFDIPKIYSSEAIKSYQGKSLGTRPPHVFAIADKAFRDMKVLKMSQSIIVSGESGA 155
VNPY +P +Y++E + +Y+GK PPH+F+I+D A++ M + +QSI+++GESGA
Sbjct: 124 TVNPYKWLP-VYNAEVVAAYRGKKRSEAPPHIFSISDNAYQYMLTDRENQSILITGESGA 182
Query: 156 GKTENTKFVLRYLTESYGTGQ------------DIDDRIVEANPLLEAFGNAKTVRNNNS 203
GKT NTK V++Y G ++D+I++ANP LEAFGNAKTVRN+NS
Sbjct: 183 GKTVNTKRVIQYFASIAAIGDRGKKDNANANKGTLEDQIIQANPALEAFGNAKTVRNDNS 242
Query: 204 SRFGKFVEIHFNEKSSVVGGFVSHYLLEKSRICVQGKEERNYHIFYRLCAGASEDIREKL 263
SRFGKF+ IHF + + YLLEKSR+ Q K ERNYHIFY++ + ++ + L
Sbjct: 243 SRFGKFIRIHFGATGKLASADIETYLLEKSRVIFQLKAERNYHIFYQILSNKKPELLDML 302
Query: 264 HLSSPDNFRYLNRGCTRYFANKETDKQILQNRKSPEYLKAGSMKDPLLDDHGDFIRMCTA 323
+ N ++ G + +DD + + +A
Sbjct: 303 --------------------------LVTNNPYDYAFVSQGEVSVASIDDSEELMATDSA 336
Query: 324 MKKIGLDDEEKLDLFRVVAGVLHLGNIDFEEAGSTSGGCNLKNKSAQSLEYCAELLGLDQ 383
+G EEK ++++ ++H GN+ F++ + + + A L+GL+
Sbjct: 337 FDVLGFTSEEKAGVYKLTGAIMHYGNMKFKQKQREE---QAEPDGTEDADKSAYLMGLNS 393
Query: 384 DDLRVSLT-TRVMLTTAGGTKGTVIKVPLKVEQANNARDALAKTVYSHLFDHVVNRVNQC 442
DL L RV + TKG V+Q + ALAK VY +F+ +V R+N
Sbjct: 394 ADLLKGLCHPRVKVGNEYVTKGQ------SVQQVYYSIGALAKAVYEKMFNWMVTRINAT 447
Query: 443 FPF-ETSSYFIGVLDIAGFEYFEHNSFEQFCINYCNEKLQQFFNERILKEEQELYQKEGL 501
+ YFIGVLDIAGFE F+ NSFEQ CIN+ NEKLQQFFN + EQE Y+KEG+
Sbjct: 448 LETKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGI 507
Query: 502 GVNEVHY-VDNQDCIDLIEAKLVGILDILDEENRLPQPSDQHFTSAVHQKHKDHFRLTIP 560
+ + +D Q CIDLIE K +GI+ IL+EE P+ +D F + ++ H +
Sbjct: 508 EWTFIDFGMDLQACIDLIE-KPMGIMSILEEECMFPKATDMTFKAKLYDNH-------LG 559
Query: 561 RKSKLAVHRNI--RDDEGFIIRHFAGAVCYETTQFVEKNNDALHMSLESLICESRDKFIR 618
+ + RNI + + F + H+AG V Y ++EKN D L+ ++ +L +S K +
Sbjct: 560 KSNNFQKPRNIKGKQEAHFSLIHYAGTVDYNILGWLEKNKDPLNETVVALYQKSSLKLMA 619
Query: 619 ELFES--STNNNKDTKQKAGK---LSFISVGNKFKTQLNLLLDKLRSTGASFIRCIKPNL 673
LF S + + K K GK SF +V + LN L+ LR+T F+RCI PN
Sbjct: 620 TLFSSYATADTGDSGKSKGGKKKGSSFQTVSALHRENLNKLMTNLRTTHPHFVRCIIPNE 679
Query: 674 KMTSHHFEGAQILSQLQCSGMVSVLDLMQGGYPSRASFHELYNMYKKYMPDKLAR---LD 730
+ + ++ QL+C+G++ + + + G+P+R + + Y+ P + +D
Sbjct: 680 RKAPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILNPVAIPEGQFID 739
Query: 731 PRLFCKALFKALGLNENDYKFGLTKVFFRPGKFAEFDQIMKSDPDHLAELVKRVNHWLTC 790
R + L +L ++ N YKFG TKVFF+ G +++ + L+ ++
Sbjct: 740 SRKGTEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMR---DERLSRII--------- 787
Query: 791 SRWKKVQWCSLSVIKLKNKIKYRAEACIKMQKTIRMWLCKR-----RHKPRIDGLVKVGT 845
+R + L I+ K KI R +A + +Q IR ++ + + +I L+K
Sbjct: 788 TRMQAQARGQLMRIEFK-KIVERRDALLVIQWNIRAFMGVKNWPWMKLYFKIKPLLKSAE 846
Query: 846 LKKRLDKFNEVVSVLKDGKPEMNKQIKNLEISIDTLMAKIKSTMMTQEQIQKEYDALVKS 905
+K + E +K+ + + K LE + +++ ++ Q Q+Q E D L +
Sbjct: 847 TEKEMATMKEEFGRIKETLEKSEARRKELE---EKMVSLLQEKNDLQLQVQAEQDNLNDA 903
Query: 906 SEELLSALQKKKQQEEEAERL-RRIQEEMEKE-----RKRREEDE-KRRRKEEEERRMKL 958
E ++ K Q E + + + R+++E E +KR+ EDE +K+ ++ + L
Sbjct: 904 EERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTL 963
Query: 959 EMEAKRKQEEEERKKREDDEKRIQAEVEAQLARQKE--EESQQQAVLE-QERRDRELALR 1015
K K E + K +E E+ A+L ++K+ +E+ QQA+ + Q D+ +L
Sbjct: 964 AKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQVEEDKVNSLS 1023
Query: 1016 IAQSEAELISDEAQADL 1032
++ + E D+ + L
Sbjct: 1024 KSKVKLEQQVDDLEGSL 1040
Score = 63.5 bits (153), Expect = 1e-09
Identities = 67/251 (26%), Positives = 118/251 (47%), Gaps = 34/251 (13%)
Query: 795 KVQWCSLSVIKLKNKIKYRAEACIKMQKTIRMWLCKRRHKPRIDGLVKVGTLKKRLDKFN 854
KV S S +KL+ ++ E ++ +K +RM L R K +++G +K+
Sbjct: 1018 KVNSLSKSKVKLEQQVD-DLEGSLEQEKKVRMDL--ERAKRKLEGDLKLT---------Q 1065
Query: 855 EVVSVLKDGKPEMNKQIKNLEISIDTLMAKIKSTMMTQEQIQKEYDALVKSSEELLSALQ 914
E + L++ K ++ +++K E I+ +KI+ + Q+QK+ EEL
Sbjct: 1066 ESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQVLALQLQKKLKENQARIEEL----- 1120
Query: 915 KKKQQEEEAERLRRIQEEMEKERKRREEDEKRRRKEEEERRMKLEMEAKRKQEEEERKKR 974
++E EAER R + E + RE +E R EE +++E +K+E E +K R
Sbjct: 1121 ---EEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMR 1177
Query: 975 ED-DEKRIQAEVEAQLARQKEEES------------QQQAVLEQERRDRELALRIAQSEA 1021
D +E +Q E A R+K +S + + LE+E+ + +L L S
Sbjct: 1178 RDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNM 1237
Query: 1022 ELISDEAQADL 1032
E I +A+A+L
Sbjct: 1238 EQII-KAKANL 1247
Score = 56.2 bits (134), Expect = 2e-07
Identities = 48/200 (24%), Positives = 97/200 (48%), Gaps = 11/200 (5%)
Query: 855 EVVSVLKDGKPEMNKQIKNLEISIDTLMAKIKSTMMTQEQIQKEYDALVKSSEELLSALQ 914
E V ++ + + K I + + + L K + T E+++K + +K + L +
Sbjct: 1745 EAVQECRNAEEKAKKAITDAAMMAEELK-KEQDTSAHLERMKKNMEQTIKDLQHRLDEAE 1803
Query: 915 K------KKQQEEEAERLRRIQEEMEKERKRREEDEKRRRKEEEERRMKLEMEAKRKQEE 968
+ KKQ ++ R+R ++ E+E E+KR E K RK ERR+K E+ + ++++
Sbjct: 1804 QIALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGMRK--SERRIK-ELTYQTEEDK 1860
Query: 969 EERKKREDDEKRIQAEVEAQLARQKEEESQQQAVLEQERRDRELALRIAQSEAELISDEA 1028
+ + +D ++Q +V+A + +E E Q L + R+ + L A+ A++ +
Sbjct: 1861 KNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQH-ELDEAEERADIAESQV 1919
Query: 1029 QADLALRRNDGTRPKMTPEQ 1048
A R+ G + KM E+
Sbjct: 1920 NKLRAKSRDIGAKQKMHDEE 1939
Score = 54.3 bits (129), Expect = 7e-07
Identities = 73/307 (23%), Positives = 131/307 (42%), Gaps = 44/307 (14%)
Query: 829 CKRRHKPRIDGLVKVGTLKKRLDKFNEVVSVLKDGKPEMNKQIKNLEISIDTL---MAKI 885
C + K +I KV + +RL+ E+ + L K ++ + L+ ID L +AK+
Sbjct: 907 CDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKV 966
Query: 886 KSTMMTQEQIQKEYDALVKSSEELLSALQKKKQ--QEEEAERLRRIQEEMEKERKRRE-- 941
+ E K + +E+++ L K+K+ QE + L +Q E +K +
Sbjct: 967 EKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQVEEDKVNSLSKSK 1026
Query: 942 --------------EDEKRRRKEEEERRMKLEMEAKRKQE---EEERKKREDDEKRIQAE 984
E EK+ R + E + KLE + K QE + E K + +EK + E
Sbjct: 1027 VKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKE 1086
Query: 985 VEAQLARQKEEESQQQAVLEQERRDRELALRIAQSEAELISDE-AQADLALRRNDGTRPK 1043
+ K E+ Q A L+ +++ +E RI + E EL ++ A+A + R+D
Sbjct: 1087 FDINQQNSKIEDEQVLA-LQLQKKLKENQARIEELEEELEAERTARAKVEKLRSD----- 1140
Query: 1044 MTPEQMAKEMSEFLSRGPAVLATKAAAGTKKYDLSKWKYAEL----RDTINTSCDIELLA 1099
+++E+ E R L A + + +++K + AE RD + E A
Sbjct: 1141 -----LSRELEEISER----LEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATA 1191
Query: 1100 ACREEFH 1106
A + H
Sbjct: 1192 AALRKKH 1198
Score = 49.3 bits (116), Expect = 2e-05
Identities = 59/250 (23%), Positives = 112/250 (44%), Gaps = 43/250 (17%)
Query: 808 NKIKYRAEACIKMQKTIRMWLCKRRHKPRIDGLVKVGTLKKRLDKFNEVVSVLKDGKPEM 867
N+IK E + +K M KR H+ +D L +L NEV+ V K + ++
Sbjct: 1568 NQIKAEIERKLA-EKDEEMEQAKRNHQRVVDSLQT--SLDAETRSRNEVLRVKKKMEGDL 1624
Query: 868 NKQIKNLEISIDTLMA-----KIKSTMMTQEQIQKEYDALVKSSEELLSAL----QKKKQ 918
N+ +++S MA ++KS + Q + D V+++++L + ++
Sbjct: 1625 NEM--EIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNL 1682
Query: 919 QEEEAERLRRIQEEMEKERKRREEDEKRRRKEEEERRMKLEMEAKRKQEEEERKKREDDE 978
+ E E LR + E+ E+ RK E++ E R++L + ++ ++KK E D
Sbjct: 1683 LQAELEELRAVVEQTERSRKLAEQE-----LIETSERVQL-LHSQNTSLINQKKKMESDL 1736
Query: 979 KRIQAEVE--------------------AQLARQKEEESQQQAVLEQERRDRELALRIAQ 1018
++Q+EVE A +A + ++E A LE+ +++ E ++ Q
Sbjct: 1737 TQLQSEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQ 1796
Query: 1019 ---SEAELIS 1025
EAE I+
Sbjct: 1797 HRLDEAEQIA 1806
Score = 48.5 bits (114), Expect = 4e-05
Identities = 63/283 (22%), Positives = 118/283 (41%), Gaps = 46/283 (16%)
Query: 860 LKDGKPEMNKQIKNLEISIDTLMAKIKSTMMTQEQIQKEYDAL---VKSSEELLSALQKK 916
L++ K ++ +++++ E +++ + AK S T+ ++Q E + L V+ S +AL KK
Sbjct: 1388 LEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKK 1447
Query: 917 -----------KQQEEEAE--------RLRRIQEEMEKERKRREED------EKRRRKEE 951
KQ+ EE++ R + E+ K + EE KR K
Sbjct: 1448 QRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNL 1507
Query: 952 EERRMKL------------EMEAKRKQEEEERKKREDDEKRIQAEV---EAQLARQKEEE 996
+E L E+E RKQ E E+ + + + +A + E ++ R + E
Sbjct: 1508 QEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEF 1567
Query: 997 SQQQAVLEQERRDRELALRIAQSEAELISDEAQADL---ALRRNDGTRPKMTPEQMAKEM 1053
+Q +A +E++ +++ + A+ + + D Q L RN+ R K E EM
Sbjct: 1568 NQIKAEIERKLAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEM 1627
Query: 1054 SEFLSRGPAVLATKAAAGTKKYDLSKWKYAELRDTINTSCDIE 1096
LS + A L K +L D + + D++
Sbjct: 1628 EIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLK 1670
Score = 44.3 bits (103), Expect = 8e-04
Identities = 47/198 (23%), Positives = 94/198 (47%), Gaps = 13/198 (6%)
Query: 846 LKKRLDKFNEVVSVLKDGKPEMNKQIKNLEI---SIDTLMAKIKS----TMMTQEQIQKE 898
L K+ F+++++ K E ++++ + S+ T + K+K+ ++ E ++E
Sbjct: 1444 LDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRE 1503
Query: 899 YDALVKSSEELLSALQKKKQQEEEAERLRRIQEEMEKERKRREEDEKRRRKEEEERRMKL 958
L + +L L + + E E++R+ E + E + E+ + + EE + ++
Sbjct: 1504 NKNLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRA 1563
Query: 959 EMEAKRKQEEEERKKREDDEKRIQAEVEAQLARQKEEESQQQAVLEQERRDRELALRIAQ 1018
++E + + E ERK E DE+ QA+ Q+ +S Q + L+ E R R LR+ +
Sbjct: 1564 QLEFNQIKAEIERKLAEKDEEMEQAKRN----HQRVVDSLQTS-LDAETRSRNEVLRVKK 1618
Query: 1019 S-EAELISDEAQADLALR 1035
E +L E Q A R
Sbjct: 1619 KMEGDLNEMEIQLSHANR 1636
Score = 40.8 bits (94), Expect = 0.008
Identities = 55/268 (20%), Positives = 107/268 (39%), Gaps = 37/268 (13%)
Query: 791 SRWKKVQWCSLSVIKLKNKIKYRAEACIKMQKTIRMWLCKRRHKPRIDGLVKVGTLKKRL 850
S K+ + S + KLKN + E ++ K + D ++G K +
Sbjct: 1471 SSQKEARSLSTELFKLKNAYEESLEHLETFKREN-----KNLQEEISDLTEQLGEGGKNV 1525
Query: 851 DKFNEVVSVLKDGKPEMNKQIKNLEISIDTLMAKIKSTMMTQEQIQKEYDALVKSSEELL 910
+ +V L+ K E+ ++ E S++ KI + QI+ E + + +E +
Sbjct: 1526 HELEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEM 1585
Query: 911 SALQKKKQQEEEAERLRRIQEEMEKERKRREEDEKRRRKEEEE-RRMKLEMEAKRKQEEE 969
++ Q+ ++ +Q ++ E + R E + ++K E + M++++ + E
Sbjct: 1586 EQAKRNHQRVVDS-----LQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAAE 1640
Query: 970 ERK--------------------KREDDEKRIQAEVEAQLARQKEEESQQQAVLEQERRD 1009
+K + DD K A VE + + E + +AV+EQ R
Sbjct: 1641 AQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERS 1700
Query: 1010 RELALRIAQSEAELISDEAQADLALRRN 1037
R+LA E ELI + L +N
Sbjct: 1701 RKLA------EQELIETSERVQLLHSQN 1722
Score = 39.3 bits (90), Expect = 0.025
Identities = 54/280 (19%), Positives = 118/280 (42%), Gaps = 39/280 (13%)
Query: 843 VGTLKKRLDKFNEVVSVLKDGKPEMNKQIKNLEISIDTLM---AKIKSTMMTQEQIQKEY 899
V L +++D V L+ K E ++ ++ +++ ++ A ++ T E EY
Sbjct: 1202 VAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEY 1261
Query: 900 DALVKSSEELLS--ALQKKKQQEEEAERLRRIQE----------------EMEKERKRRE 941
++ ++ L+ Q+ K Q E E R+++E + ++ KR+
Sbjct: 1262 RVKLEEAQRSLNDFTTQRAKLQTENGELARQLEEKEALISQLTRGKLSYTQQMEDLKRQL 1321
Query: 942 EDEKRRRK--EEEERRMKLEMEAKRKQEEEERKKREDDEKRI-QAEVEAQLARQKEEESQ 998
E+E + + + + + + R+Q EEE + + + ++ + +A E R K E
Sbjct: 1322 EEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDA 1381
Query: 999 QQAVLEQERRDRELALRIAQSEAELISDEAQADLALRRNDGTRPKMTPEQMAKEMSEFLS 1058
Q E E ++LA R+ +E + + A+ + + T ++ E+ + +
Sbjct: 1382 IQRTEELEEAKKKLAQRLQDAEEAVEAVNAKC---------SSLEKTKHRLQNEIEDLMV 1432
Query: 1059 RGPAVLATKAAAGTKKYD----LSKW--KYAELRDTINTS 1092
A AA K+ + L++W KY E + + +S
Sbjct: 1433 DVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESS 1472
>gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta [Homo
sapiens]
Length = 1983
Score = 441 bits (1133), Expect = e-123
Identities = 343/1211 (28%), Positives = 588/1211 (48%), Gaps = 101/1211 (8%)
Query: 3 DGKP-VWAPHPTDGFQMGNIVDIGPDS-LTIEPLNQKGKTFLALINQVFPAEEDSKKDVE 60
DGK VW P D + + +T+E +QK + ++ P +E
Sbjct: 72 DGKKRVWVPDEQDAYVEAEVKSEATGGRVTVETKDQK--VLMVREAELQPMNPPRFDLLE 129
Query: 61 DNCSLMYLNEATLLHNIKVRYSKDRIYTYVANILIAVNPYFDIPKIYSSEAIKSYQGKSL 120
D + +LNEA++LHN++ RY++ IYTY + +NPY +P +Y++ + +Y+GK
Sbjct: 130 DMAMMTHLNEASVLHNLRQRYARWMIYTYSGLFCVTINPYKWLP-VYTASVVAAYKGKRR 188
Query: 121 GTRPPHVFAIADKAFRDMKVLKMSQSIIVSGESGAGKTENTKFVLRY------LTESYG- 173
PPH++A+AD A+ DM + +QS++++GESGAGKT NTK V++Y L + G
Sbjct: 189 SDSPPHIYAVADNAYNDMLRNRDNQSMLITGESGAGKTVNTKRVIQYFAIVAALGDGPGK 248
Query: 174 --------TGQDIDDRIVEANPLLEAFGNAKTVRNNNSSRFGKFVEIHFNEKSSVVGGFV 225
TG ++D+I+EANP +EAFGNAKT+RN+NSSRFGKF+ IHF + +
Sbjct: 249 KAQFLATKTGGTLEDQIIEANPAMEAFGNAKTLRNDNSSRFGKFIRIHFGPSGKLASADI 308
Query: 226 SHYLLEKSRICVQGKEERNYHIFYRLCAGASEDIREKLHLS-SPDNFRYLNRGCTRYFAN 284
YLLEKSR+ Q ER+YH++Y++ +G ++++ L LS +P ++ + ++G
Sbjct: 309 DSYLLEKSRVIFQLPGERSYHVYYQILSGRKPELQDMLLLSMNPYDYHFCSQGVI----- 363
Query: 285 KETDKQILQNRKSPEYLKAGSMKDPLLDDHGDFIRMCTAMKKIGLDDEEKLDLFRVVAGV 344
+ N E L + DH AM +G +EK +++V +
Sbjct: 364 ------TVDNMNDGEEL--------IATDH--------AMDILGFSVDEKCACYKIVGAL 401
Query: 345 LHLGNIDFEEAGSTSGGCNLKNKSAQSLEYCAELLGLDQDD-LRVSLTTRVMLTTAGGTK 403
LH GN+ F++ + +S + A L+G+ D L+ L RV + TK
Sbjct: 402 LHFGNMKFKQKQREE---QAEADGTESADKAAYLMGVSSGDLLKGLLHPRVRVGNEYVTK 458
Query: 404 GTVIKVPLKVEQANNARDALAKTVYSHLFDHVVNRVNQCFPFE-TSSYFIGVLDIAGFEY 462
G VEQ A ALAK Y LF +V+R+NQ + +FIGVLDIAGFE
Sbjct: 459 GQ------SVEQVVFAVGALAKATYDRLFRWLVSRINQTLDTKLPRQFFIGVLDIAGFEI 512
Query: 463 FEHNSFEQFCINYCNEKLQQFFNERILKEEQELYQKEGLGVNEVHY-VDNQDCIDLIEAK 521
FE NSFEQ CIN+ NEKLQQFFN+ + EQE Y++EG+ + + +D Q CIDLIE K
Sbjct: 513 FEFNSFEQLCINFTNEKLQQFFNQHMFVLEQEEYKREGIDWVFIDFGLDLQPCIDLIE-K 571
Query: 522 LVGILDILDEENRLPQPSDQHFTSAVHQKH---KDHFRLTIP-RKSKLAVHRNIRDDEGF 577
+GIL IL+EE P+ SD F + ++ H +F+ P +K K H F
Sbjct: 572 PLGILSILEEECMFPKASDASFRAKLYDNHAGKSPNFQQPRPDKKRKYQAH--------F 623
Query: 578 IIRHFAGAVCYETTQFVEKNNDALHMSLESLICESRDKFIRELFESSTNNNKDTKQKAG- 636
+ H+AG V Y ++EKN D L+ ++ + +S+++ + L+E+ + K+G
Sbjct: 624 EVVHYAGVVPYSIVGWLEKNKDPLNETVVPIFQKSQNRLLATLYENYAGSCSTEPPKSGV 683
Query: 637 ------KLSFISVGNKFKTQLNLLLDKLRSTGASFIRCIKPNLKMTSHHFEGAQILSQLQ 690
SF +V K LN L+ LR+T F+RCI PN T + +L QL+
Sbjct: 684 KEKRKKAASFQTVSQLHKENLNKLMTNLRATQPHFVRCIVPNENKTPGVMDAFLVLHQLR 743
Query: 691 CSGMVSVLDLMQGGYPSRASFHELYNMYKKYMPDKL---ARLDPRLFCKALFKALGLNEN 747
C+G++ + + + G+P+R + + Y+ P + +D R + L +L L+
Sbjct: 744 CNGVLEGIRICRQGFPNRLLYTDFRQRYRILNPSAIPDDTFMDSRKATEKLLGSLDLDHT 803
Query: 748 DYKFGLTKVFFRPGKFAEFDQIMKSDPDHLAELVK-RVNHWLTCSRWKKVQWCSLSVIKL 806
Y+FG TKVFF+ G +++ + L++ R L ++++ ++ +
Sbjct: 804 QYQFGHTKVFFKAGLLGVLEELRDQRLAKVLTLLQARSRGRLMRLEYQRLLGGRDALFTI 863
Query: 807 KNKIKYRAEACIKMQKTIRMWLCKRRHKPRIDGLVKVGTLKKRLDKFNEVVSVLKDGKPE 866
+ I RA +K ++++ + ++ L+ L ++ + + E
Sbjct: 864 QWNI--RAFNAVKNWSWMKLFFKMKPLLRSAQAEEELAALRAELRGLRGALAAAEAKRQE 921
Query: 867 MNKQIKNLEISIDTLMAKIKSTMMTQEQIQKEYDALVKSSEELLSALQKKKQQEEEAERL 926
+ + ++ + L ++++ ++ L+KS +L K K+ E E
Sbjct: 922 LEETHVSITQEKNDLALQLQAEQDNLADAEERCHLLIKSKVQLEG---KVKELSERLEDE 978
Query: 927 RRIQEEMEKERKRREEDEKRRRKEEEERRMKLEMEAKRKQEEEERKKREDDEKRIQAEVE 986
+ ++ R++ E++ +K+ ++ ++ L K KQ E + K +E E
Sbjct: 979 EEVNADLAARRRKLEDECTELKKDIDDLKLTLAKAEKEKQATENKVKNLTEEMAALDESV 1038
Query: 987 AQLARQKE--EESQQQAVLE-QERRDRELALRIAQSEAELISDEAQADLALRRNDGTRPK 1043
A+L ++K+ +E+ QQA+ + Q DR AL ++A+L ++ DL + +
Sbjct: 1039 ARLTKEKKALQEAHQQALGDLQAEEDRVSAL----TKAKLRLEQQVEDLECSLEQEKKLR 1094
Query: 1044 MTPEQMAKEMSEFLSRGPAVLATKAAAGTKKYDLSKWKYAELRDTINTSCDIELLAA--- 1100
M E+ +++ L +A A + + K K +EL D +LL A
Sbjct: 1095 MDTERAKRKLEGDLKLTQESVADAAQDKQQLEEKLKKKDSELSQLSLRVEDEQLLGAQMQ 1154
Query: 1101 --CREEFHRRLKVYHAWKSKNKKRNTETEQRAPKSVTDYDFAPFLNNSPQQNPAAQIPAR 1158
+E R ++ +++ R +QRA + + + L + + + R
Sbjct: 1155 KKIKELQARAEELEEELEAERAARARVEKQRAEAARELEELSERLEEAGGASAGQREGCR 1214
Query: 1159 QREIEMNRQQR 1169
+RE E+ R +R
Sbjct: 1215 KREAELGRLRR 1225
Score = 56.6 bits (135), Expect = 1e-07
Identities = 59/245 (24%), Positives = 110/245 (44%), Gaps = 23/245 (9%)
Query: 815 EACIKMQKTIRMWLCKRRHKPRIDGLVKVGTLKKRLDKFNEVVSVLKDGKPEMNKQIKNL 874
E ++ +K +RM R K +++G +K+ E V+ K ++ +++K
Sbjct: 1084 ECSLEQEKKLRM--DTERAKRKLEGDLKLT---------QESVADAAQDKQQLEEKLKKK 1132
Query: 875 EISIDTLMAKIKSTMMTQEQIQKEYDALVKSSEELLSALQKKKQQEEEAERLRRIQEEME 934
+ + L +++ + Q+QK+ L +EEL L EAER R + E +
Sbjct: 1133 DSELSQLSLRVEDEQLLGAQMQKKIKELQARAEELEEEL--------EAERAARARVEKQ 1184
Query: 935 KERKRREEDEKRRRKEEEERRMKLEMEAKRKQEEE-ERKKREDDEKRIQAEVEAQLARQK 993
+ RE +E R EE + E RK+E E R +RE +E ++ E R+K
Sbjct: 1185 RAEAARELEELSERLEEAGGASAGQREGCRKREAELGRLRRELEEAALRHEATVAALRRK 1244
Query: 994 EEESQQQAVLEQERRDRELALRIAQSEAELISDEAQADLALRRNDGTRPKMTPEQMAKEM 1053
+ E + + EQ + + ++ + ++EL + DLA TR K + E++ +
Sbjct: 1245 QAEGAAE-LGEQVDSLQRVRQKLEKEKSELRME--VDDLAANVETLTRAKASAEKLCRTY 1301
Query: 1054 SEFLS 1058
+ LS
Sbjct: 1302 EDQLS 1306
Score = 52.0 bits (123), Expect = 4e-06
Identities = 67/284 (23%), Positives = 119/284 (41%), Gaps = 25/284 (8%)
Query: 828 LCKRRHKPRIDGLVKVGTLKKRLDKFNEVVSVLKDGKPEMNKQIKNLEISIDTLMAKIKS 887
LC+ + +KV L+++L + L+ E+++ ++ E I L
Sbjct: 1297 LCRTYEDQLSEAKIKVEELQRQLADASTQRGRLQTESGELSRLLEEKECLISQLSRGKAL 1356
Query: 888 TMMTQEQIQKEYDALVKSSEELLSALQK--------KKQQEEEAERLRRIQE-------E 932
+ E+++++ + K+ L A+Q ++Q EEEAE +Q E
Sbjct: 1357 AAQSLEELRRQLEEESKAKSALAHAVQALRHDCDLLREQHEEEAEAQAELQRLLSKANAE 1416
Query: 933 MEKERKRREEDEKRRRKEEEERRMKLEMEAKRKQEEEER-----KKREDDEKRIQAEVEA 987
+ + R + E D +R +E EE + KL + + +E E E + R+Q E E
Sbjct: 1417 VAQWRSKYEADAIQRTEELEEAKKKLALRLQEAEEGVEAANAKCSSLEKAKLRLQTESE- 1475
Query: 988 QLARQKEEESQQQAVLEQERRDRELALRIAQSEAELISDEAQADLALRRNDGT---RPKM 1044
+ + E + A L++++R E AL + + E + E +A R GT R +
Sbjct: 1476 DVTLELERATSAAAALDKKQRHLERALEERRRQEEEMQRELEAAQRESRGLGTELFRLRH 1535
Query: 1045 TPEQMAKEMSEFLSRGPAVLATKAAAGTKKYDLSKWKYAELRDT 1088
E+ A E E L R L + + T + LS EL T
Sbjct: 1536 GHEE-ALEALETLKRENKNLQEEISDLTDQVSLSGKSIQELEKT 1578
Score = 45.4 bits (106), Expect = 3e-04
Identities = 55/262 (20%), Positives = 115/262 (43%), Gaps = 19/262 (7%)
Query: 884 KIKSTMMTQEQIQKEYDALVKSSEELLSALQKKKQQEEEAERLRRIQEEMEKERKRREED 943
++ S +++++KE L ++L + ++ + + AE+L R E+ E K + E+
Sbjct: 1255 QVDSLQRVRQKLEKEKSELRMEVDDLAANVETLTRAKASAEKLCRTYEDQLSEAKIKVEE 1314
Query: 944 EKRRRKEEEERRMKLEME----AKRKQEEEERKKREDDEKRIQAEVEAQLARQKEEESQQ 999
+R+ + +R +L+ E ++ +E+E + K + A+ +L RQ EEES+
Sbjct: 1315 LQRQLADASTQRGRLQTESGELSRLLEEKECLISQLSRGKALAAQSLEELRRQLEEESKA 1374
Query: 1000 QAVL----EQERRDRELALRIAQSEAELISDEAQADLALRRNDGTRPKMTPEQMAKEMSE 1055
++ L + R D +L + EAE E Q L+ + + + E A + +E
Sbjct: 1375 KSALAHAVQALRHDCDLLREQHEEEAE-AQAELQRLLSKANAEVAQWRSKYEADAIQRTE 1433
Query: 1056 FLSRGPAVLATK--------AAAGTKKYDLSKWKYAELRDTINTSCDIELLAACREEFHR 1107
L LA + AA K L K K ++ + + ++E + +
Sbjct: 1434 ELEEAKKKLALRLQEAEEGVEAANAKCSSLEKAKLRLQTESEDVTLELERATSAAAALDK 1493
Query: 1108 RLKVYHAWKSKNKKRNTETEQR 1129
+ + H ++ ++R E E +
Sbjct: 1494 KQR--HLERALEERRRQEEEMQ 1513
Score = 43.9 bits (102), Expect = 0.001
Identities = 48/206 (23%), Positives = 93/206 (45%), Gaps = 21/206 (10%)
Query: 860 LKDGKPEMNKQIKNLEISIDTLMAKIKSTMMTQEQIQKEYDALVKSSEELLSALQKKKQQ 919
L++ K ++ +++ E ++ AK S + ++Q E SE++ L++
Sbjct: 1435 LEEAKKKLALRLQEAEEGVEAANAKCSSLEKAKLRLQTE-------SEDVTLELERATSA 1487
Query: 920 EEEAERLRRIQEEMEKERKRREEDEKRRRK--EEEERRMKLEMEAKRKQEEE-----ERK 972
++ +R E +ER+R+EE+ +R + + E R + E+ R EE E
Sbjct: 1488 AAALDKKQRHLERALEERRRQEEEMQRELEAAQRESRGLGTELFRLRHGHEEALEALETL 1547
Query: 973 KREDDEKRIQAEVEAQLARQKEEESQQQAVLEQERRDRELALRIAQSEAELISDEAQADL 1032
KRE+ K +Q E+ + L Q + LE+ ++ AL +SE + +EA+ L
Sbjct: 1548 KREN--KNLQEEI-SDLTDQVSLSGKSIQELEKTKK----ALEGEKSEIQAALEEAEGAL 1600
Query: 1033 ALRRNDGTRPKMTPEQMAKEMSEFLS 1058
L R ++ Q+ E+ L+
Sbjct: 1601 ELEETKTLRIQLELSQVKAEVDRKLA 1626
Score = 43.5 bits (101), Expect = 0.001
Identities = 39/149 (26%), Positives = 76/149 (51%), Gaps = 17/149 (11%)
Query: 886 KSTMMTQEQIQKEYDALVKSSEELLSALQKKKQQEEEAERL----RRIQEEMEKERKRRE 941
++T + ++ + E D L + S E+ A Q++++ EE+A++ + EE++KE+
Sbjct: 1768 QNTGLLNQKKKLEAD-LAQLSGEVEEAAQERREAEEKAKKAITDAAMMAEELKKEQDTSA 1826
Query: 942 EDEKRRRKEEEERRMKLEMEAKRKQEEEERKKREDDEKRIQA------EVEAQL-ARQKE 994
E+ ++ E+ R E + + EE E+ +K++Q E+EA+L A QK+
Sbjct: 1827 HLERMKKTLEQTVR-----ELQARLEEAEQAALRGGKKQVQKLEAKVRELEAELDAEQKK 1881
Query: 995 EESQQQAVLEQERRDRELALRIAQSEAEL 1023
+ V + ERR +ELA + + L
Sbjct: 1882 HAEALKGVRKHERRVKELAYQAEEDRKNL 1910
Score = 41.2 bits (95), Expect = 0.006
Identities = 59/252 (23%), Positives = 110/252 (43%), Gaps = 31/252 (12%)
Query: 893 EQIQKEYDALVKSSEELLSALQKKKQQEEEAERLRRIQEEMEKERKRREEDEKRRRKEEE 952
E +++E L + +L + + +E E+ ++ E + E + E+ + + EE
Sbjct: 1545 ETLKRENKNLQEEISDLTDQVSLSGKSIQELEKTKKALEGEKSEIQAALEEAEGALELEE 1604
Query: 953 ERRMKLEMEAKRKQEEEERKKREDDEKRIQAEVEAQLARQKEEESQQ-QAVLEQERRDRE 1011
+ +++++E + + E +RK E DE+ A L R + + QA L+ E R R
Sbjct: 1605 TKTLRIQLELSQVKAEVDRKLAEKDEEC------ANLRRNHQRAVESLQASLDAETRARN 1658
Query: 1012 LALRIAQS-EAELISDEAQADLALRR----NDGTR---PKMTPEQMAKEMSEFLSRGPAV 1063
ALR+ + E +L E Q A R+ TR ++ EQ ++ + L+ A
Sbjct: 1659 EALRLKKKMEGDLNDLELQLGHATRQATEAQAATRLMQAQLKEEQAGRDEEQRLA---AE 1715
Query: 1064 LATKAAAGTKKYDLSKWKYAELRDTINTS------CDIELLAACREEFHRRLKVYHAWKS 1117
L +A A ++ L + ELR + + ELL A RL + H+ +
Sbjct: 1716 LHEQAQALERRASLLAAELEELRAALEQGERSRRLAEQELLEAT-----ERLNLLHSQNT 1770
Query: 1118 --KNKKRNTETE 1127
N+K+ E +
Sbjct: 1771 GLLNQKKKLEAD 1782
Score = 38.9 bits (89), Expect = 0.032
Identities = 66/314 (21%), Positives = 129/314 (41%), Gaps = 36/314 (11%)
Query: 840 LVKVGTLKKRLDKFNEVVSVLKDGKPEMNKQIKNLEISIDTLMAKIKSTMMTQEQIQKEY 899
L + TL+ +L+ ++V + + E +++ NL + + +++++ + + + E
Sbjct: 1602 LEETKTLRIQLE-LSQVKAEVDRKLAEKDEECANLRRNHQRAVESLQASLDAETRARNEA 1660
Query: 900 DALVKSSEELLSALQKK----KQQEEEAERLRRIQEEMEKERKRREEDEKRRRKEEEERR 955
L K E L+ L+ + +Q EA+ R+ + KE + ++E+R E E+
Sbjct: 1661 LRLKKKMEGDLNDLELQLGHATRQATEAQAATRLMQAQLKEEQAGRDEEQRLAAELHEQA 1720
Query: 956 MKLEM----------EAKRKQEEEERKKREDDEKRIQA--------EVEAQLARQKEEES 997
LE E + E+ ER +R +++ ++A L QK++
Sbjct: 1721 QALERRASLLAAELEELRAALEQGERSRRLAEQELLEATERLNLLHSQNTGLLNQKKKLE 1780
Query: 998 QQQAVLEQERRDRELALRIAQSEA-ELISDEAQADLALRRNDGT-----RPKMTPEQMAK 1051
A L E + R A+ +A + I+D A L++ T R K T EQ +
Sbjct: 1781 ADLAQLSGEVEEAAQERREAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKTLEQTVR 1840
Query: 1052 EMSEFLSRGPAVLATKAA--AGTKKYDLSKWKYAELRDTINTSCDIELLAACREEFHRRL 1109
E+ L A +AA G K+ + K EL ++ A H R
Sbjct: 1841 ELQARLEE-----AEQAALRGGKKQVQKLEAKVRELEAELDAEQKKHAEALKGVRKHERR 1895
Query: 1110 KVYHAWKSKNKKRN 1123
A++++ ++N
Sbjct: 1896 VKELAYQAEEDRKN 1909
Score = 37.4 bits (85), Expect = 0.093
Identities = 37/163 (22%), Positives = 77/163 (47%), Gaps = 33/163 (20%)
Query: 843 VGTLKKRLDKFNEVVSVLKDGKPEMNKQIKNLEISIDTLMAKIKSTMMTQEQIQKEYDAL 902
V L+ RL++ + + L+ GK KQ++ LE AK++ +++ E DA
Sbjct: 1839 VRELQARLEEAEQ--AALRGGK----KQVQKLE-------AKVR-------ELEAELDAE 1878
Query: 903 VKSSEELLSALQKKK--------QQEEEAERLRRIQEEMEKERKRREEDEKRRRKEEEER 954
K E L ++K + Q EE+ + L R+Q+ ++K + + + +++ + E++
Sbjct: 1879 QKKHAEALKGVRKHERRVKELAYQAEEDRKNLARMQDLVDKLQSKVKSYKRQFEEAEQQA 1938
Query: 955 RMKLEMEAKRKQEEEERKKREDDEKRIQAEVEAQLARQKEEES 997
L K + E ++ ++R D AE +A R + ++
Sbjct: 1939 NTNLAKYRKAQHELDDAEERAD-----MAETQANKLRARTRDA 1976
>gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]
Length = 2036
Score = 440 bits (1132), Expect = e-123
Identities = 362/1249 (28%), Positives = 590/1249 (47%), Gaps = 211/1249 (16%)
Query: 7 VWAPHPTDGFQMGNIVDIGPDSLTIEPLNQKGKTFLALINQVFPAEEDSKKDVEDNCSLM 66
VW P GF+ + D G + +E L + G+ +Q+ ED L
Sbjct: 56 VWVPSELHGFEAAALRDEGEEEAEVE-LAESGRRLRLPRDQIQRMNPPKFSKAEDMAELT 114
Query: 67 YLNEATLLHNIKVRYSKDRIYTYVANILIAVNPYFDIPKIYSSEAIKSYQGKSLGTRPPH 126
LNEA++LHN++ RY IYTY + +NPY +P IY+ ++ Y+GK PPH
Sbjct: 115 CLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLP-IYTEAIVEMYRGKKRHEVPPH 173
Query: 127 VFAIADKAFRDMKVLKMSQSIIVSGESGAGKTENTKFVLRYL------------------ 168
V+A+ + A+R M + QSI+ +GESGAGKTENTK V++YL
Sbjct: 174 VYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVPAS 233
Query: 169 --TESYGTGQDIDDRIVEANPLLEAFGNAKTVRNNNSSRFGKFVEIHFNEKSSVVGGFVS 226
T SYG +++ ++++ANP+LEAFGNAKTV+N+NSSRFGKF+ I+F+ +VG +
Sbjct: 234 VSTVSYG---ELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIE 290
Query: 227 HYLLEKSRICVQGKEERNYHIFYRLCAGASEDIREKLHLSSPDNFRYLNRGCTRYFANKE 286
YLLEKSR Q K+E ++HIFY+L GA E ++ L L ++R+L G + ++
Sbjct: 291 TYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPS---SSPG 347
Query: 287 TDKQILQNRKSPEYLKAGSMKDPLLDDHGDFIRMCTAMKKIGLDDEEKLDLFRVVAGVLH 346
++++ Q +++ +G EE + + R+V+ VL
Sbjct: 348 QERELFQETLE-------------------------SLRVLGFSHEEIISMLRMVSAVLQ 382
Query: 347 LGNIDFEEAGSTSGGCNLKNKSAQSLEYCAELLGLDQDDL-RVSLTTRVMLTTAGGTKGT 405
GNI + +T N +AQ L LLGL D R LT R+ + +
Sbjct: 383 FGNIALKRERNTDQATMPDNTAAQKL---CRLLGLGVTDFSRALLTPRIKVG-----RDY 434
Query: 406 VIKVPLKVEQANNARDALAKTVYSHLFDHVVNRVNQCF---PFETSSYFIGVLDIAGFEY 462
V K K EQA+ A +ALAK Y LF +V R+N+ P + +S F+G+LDIAGFE
Sbjct: 435 VQKAQTK-EQADFALEALAKATYERLFRWLVLRLNRALDRSPRQGAS-FLGILDIAGFEI 492
Query: 463 FEHNSFEQFCINYCNEKLQQFFNERILKEEQELYQKEGLGVNEVHY-VDNQDCIDLIE-- 519
F+ NSFEQ CINY NEKLQQ FN + EQE YQ+EG+ + + +D Q CIDLIE
Sbjct: 493 FQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGLDLQPCIDLIERP 552
Query: 520 AKLVGILDILDEENRLPQPSDQHFTSAVHQKHKDHFRLTIPRKSKLAVHRNIRDDEGFII 579
A G+L +LDEE P+ +D+ F V Q+ H + P R++RD F +
Sbjct: 553 ANPPGLLALLDEECWFPKATDKSFVEKVAQEQGGHPKFQRP--------RHLRDQADFSV 604
Query: 580 RHFAGAVCYETTQFVEKNNDALHMSLESLICESRDKFIRELFES---------------- 623
H+AG V Y+ +++ KN D L+ ++ +L+ +S D+ E+++
Sbjct: 605 LHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKDEHGGFQQFSFLGSFPP 664
Query: 624 ---------------------------STNNNKDTKQKAGKLSFISVGNKFKTQLNLLLD 656
S+ + + + F +VG +K L+ L+
Sbjct: 665 SPPGSAERCSSAISPPGVEGIVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKESLSRLMA 724
Query: 657 KLRSTGASFIRCIKPNLKMTSHHFEGAQILSQLQCSGMVSVLDLMQGGYPSRASFHELYN 716
L +T SF+RCI PN + + E +L QL+C+G++ + + + G+P+R F E
Sbjct: 725 TLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQ 784
Query: 717 MYKKYMPDKLAR--LDPRLFCKALFKALGLNENDYKFGLTKVFFRPGKFAEFDQ------ 768
Y+ P+ + + +D + C+ + +AL L+ N Y+ G +K+FFR G A+ ++
Sbjct: 785 RYEILTPNAIPKGFMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKV 844
Query: 769 -------------------IMKSDPDHLAELVKRVN--------HWLTCSRWKKVQWCSL 801
K A V + N HW + KV+ L
Sbjct: 845 TDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVK-PLL 903
Query: 802 SVIKLKNKIKYRAEACIKMQKTIRMWLCKRRHKPRIDGLV-----KVGTLKKRLDKFNEV 856
V + ++ RA+ ++QK + R + G V + L ++L E+
Sbjct: 904 QVTRQDEVLQARAQ---ELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAEL 960
Query: 857 VSVLKDGKPEMNKQIKNLEISIDTLMAKIKSTMMTQEQIQKEYDALVKSSEELLSALQ-- 914
+ ++ + + + + LE+ + L A++ Q+Q E L + +EL + L+
Sbjct: 961 CAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAE 1020
Query: 915 ----------------KKKQQEEEAERLRRIQEEMEKERKRREE---DEKRRRKEEEER- 954
K K+ EE+ L ++ KERK E+ + + EEEE+
Sbjct: 1021 EGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKV 1080
Query: 955 ----RMKLEMEAKRKQEEEERKKREDDEKRIQAEVEAQLARQKEEESQ--QQAVLEQERR 1008
+++L+ EA E+ +K E + ++ +L R+ + ES Q+ ++EQ++R
Sbjct: 1081 KSLNKLRLKYEATIADMEDRLRKEEKGRQELE-----KLKRRLDGESSELQEQMVEQQQR 1135
Query: 1009 DRELALRIAQSEAELISDEAQADLALRRNDGTRPKMTPEQMAKEMSEFLSRGPAVLATKA 1068
EL ++ + E EL QA LA ++G + + +E L+ L ++
Sbjct: 1136 AEELRAQLGRKEEEL-----QAALARAEDEGGARAQLLKSL-REAQAALAEAQEDLESER 1189
Query: 1069 AAGTK----KYDLSKWKYA---ELRDTINTSCDIELLAACREEFHRRLK 1110
A TK + DL + A EL DT++++ + L + RE+ LK
Sbjct: 1190 VARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELK 1238
Score = 57.8 bits (138), Expect = 7e-08
Identities = 59/222 (26%), Positives = 117/222 (52%), Gaps = 29/222 (13%)
Query: 845 TLKKRLDKFNEVVSVLKDGKPEMNKQIKNLE---ISIDTLMAKIKSTMMTQEQIQKEYDA 901
T + ++ KF E + +L+D +++K+ K LE + A+ + + + +++ +Y+A
Sbjct: 1033 TTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEA 1092
Query: 902 LVKSSEELLSALQKKKQQEEEAERLRR--------IQEEMEKERKRREEDEKRRRKEEEE 953
+ E+ L+K+++ +E E+L+R +QE+M ++++R EE + ++EEE
Sbjct: 1093 TIADMED---RLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEE 1149
Query: 954 RRMKLEMEAKRKQEEEERKKREDDEKRIQAEVEAQLARQKEE-ESQQQAVLEQERRDREL 1012
++A + E+E R K ++ E +A LA +E+ ES++ A + E++ R+L
Sbjct: 1150 ------LQAALARAEDEGGARAQLLKSLR-EAQAALAEAQEDLESERVARTKAEKQRRDL 1202
Query: 1013 -----ALRIAQSEAELISDEAQADL-ALRRNDGTRPKMTPEQ 1048
ALR + E L S AQ +L + R + T K T E+
Sbjct: 1203 GEELEALR-GELEDTLDSTNAQQELRSKREQEVTELKKTLEE 1243
Score = 57.0 bits (136), Expect = 1e-07
Identities = 71/250 (28%), Positives = 111/250 (44%), Gaps = 44/250 (17%)
Query: 842 KVGTLKKRLDKFNEVVSVLKDG--KPEMNKQ-IKNLEISIDTLMAKIKSTMMTQEQIQKE 898
KV +L K K+ ++ ++D K E +Q ++ L+ +D ++++ M+ Q+Q +E
Sbjct: 1079 KVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEE 1138
Query: 899 YDA-LVKSSEELLSAL-----------QKKKQQEEEAERLRRIQEEMEKERKRREEDEKR 946
A L + EEL +AL Q K E L QE++E ER R + EK+
Sbjct: 1139 LRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQ 1198
Query: 947 RRKEEEE--------------RRMKLEMEAKRKQEEEERKKREDDEKRI-QAEVEAQLAR 991
RR EE + E+ +KR+QE E KK ++E RI +A V+ R
Sbjct: 1199 RRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQR 1258
Query: 992 QKEEESQQQAVLEQERRDR------ELALRIAQSE--AELISDEAQADLALRRNDGTRPK 1043
+ + LEQ RR + LAL SE AEL S L R +G + +
Sbjct: 1259 HGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSS------LQTARQEGEQRR 1312
Query: 1044 MTPEQMAKEM 1053
E +E+
Sbjct: 1313 RRLELQLQEV 1322
Score = 48.9 bits (115), Expect = 3e-05
Identities = 61/256 (23%), Positives = 117/256 (45%), Gaps = 50/256 (19%)
Query: 864 KPEMNKQIKNLEISIDTLMAKIKSTMMT---QEQI----QKEYDALVKSSEELL----SA 912
+ + KQ ++L ++ L +++ T+ + Q+++ ++E L K+ EE +A
Sbjct: 1192 RTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAA 1251
Query: 913 LQKKKQQEEEAERLRRIQEEMEKERKRREEDEKRR--------------------RKEEE 952
+Q+ +Q+ +A L + E++E+ R+ + EK R R+E E
Sbjct: 1252 VQELRQRHGQA--LGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGE 1309
Query: 953 ERRMKLEMEAKRKQEEEERKKREDDEKRIQAEVEAQLAR-QKEEESQQQAVLEQERRDRE 1011
+RR +LE++ +E + R D +R +AE +L R Q E E+ A+ E E +
Sbjct: 1310 QRRRRLELQL------QEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIR 1363
Query: 1012 LALRIAQSEA------ELISDEAQADLALRRNDGTRPKMTPEQMAKEMSEFLSRGPAVLA 1065
L+ ++ +EA EL+ +E +A LAL G+R + + A + A
Sbjct: 1364 LSKELSSTEAQLHDAQELLQEETRAKLAL----GSRVRAMEAEAAGLREQLEEEAAARER 1419
Query: 1066 TKAAAGTKKYDLSKWK 1081
T + LS+W+
Sbjct: 1420 AGRELQTAQAQLSEWR 1435
Score = 45.4 bits (106), Expect = 3e-04
Identities = 44/221 (19%), Positives = 97/221 (43%), Gaps = 34/221 (15%)
Query: 861 KDGKPEMNKQIKNLEISIDTLMA----------KIKSTMMTQEQIQKEYDALVKSSEELL 910
++ + E+ +Q + L ++ L++ +++ EQ + A V E+ L
Sbjct: 1554 QEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDEL 1613
Query: 911 SALQKKKQQEEEAERLRRIQEEMEKERKRREEDEKRRRKEEEERRMKLEMEAKRKQEE-- 968
+A + K + E + + Q E + + + +E+RR+ ++ R ++E + +RKQ
Sbjct: 1614 TAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLA 1673
Query: 969 -EERKKREDDEKRIQAEVEA--------------------QLARQKEEESQQQAVLEQER 1007
RKK E + + ++A++ + +L R+ EE + + +
Sbjct: 1674 VAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQN 1733
Query: 1008 RDRELALRIAQSEAELISDE-AQADLALRRNDGTRPKMTPE 1047
R+ E L+ ++E + +E A +D A R+ R +M E
Sbjct: 1734 RESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADE 1774
Score = 43.5 bits (101), Expect = 0.001
Identities = 51/263 (19%), Positives = 111/263 (42%), Gaps = 20/263 (7%)
Query: 834 KPRIDGLVKVGTLKKRLDKFNEVVSVLKDGKPEMNKQIKNLEISIDTLMAKIKSTMMTQE 893
+ R + K+ + L+ + ++ + ++K++ + E + ++ +
Sbjct: 1331 RARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKL 1390
Query: 894 QIQKEYDALVKSSEELLSALQKKKQQEEEAERLRRIQEEMEKERKRREEDEKRRRKEEEE 953
+ A+ + L L+++ E A R + + E +RR+E+E + EE
Sbjct: 1391 ALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEE 1450
Query: 954 RRMKLEMEA----KRKQEEEERKKR-EDDEKRIQAEVEAQLARQKEEESQQQAVLEQERR 1008
R + EA +R E+ E R E +R+Q E++ + E Q+Q V E++
Sbjct: 1451 ARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELD---DATMDLEQQRQLVSTLEKK 1507
Query: 1009 DRELALRIAQSEAEL---ISDEAQADLALRRNDGTRPKMT----PEQMAKEMSEFLSRG- 1060
R+ +A+ +A + + + +A+ R + +T EQ A+E E +R
Sbjct: 1508 QRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRAL 1567
Query: 1061 ----PAVLATKAAAGTKKYDLSK 1079
A+L++K G ++L +
Sbjct: 1568 RAELEALLSSKDDVGKSVHELER 1590
Score = 43.5 bits (101), Expect = 0.001
Identities = 50/239 (20%), Positives = 107/239 (44%), Gaps = 37/239 (15%)
Query: 846 LKKRLDKFNEVVSVLKDGKPEMNKQIKNLEISIDTLMAKIKSTMMTQEQIQKEYDALVKS 905
L+ L++ ++ GK E KQ++ ++ + L +++ T ++E+I + +
Sbjct: 1680 LEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQN----RE 1735
Query: 906 SEELLSALQKKKQQEEEAERLRRIQEEMEKERKRREEDEKRRRKEEE------------E 953
SE+ L L EAE LR +E +R RR+ + R +E E
Sbjct: 1736 SEKRLKGL--------EAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILE 1787
Query: 954 RRMKLE-----MEAKRKQEEEERKKREDDEKRIQAEVEA---QLARQKEEESQQQAVLEQ 1005
+ +LE +E + ++E+ + D +++ +VE+ +L+ ++ ++ ++ +Q
Sbjct: 1788 EKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQ 1847
Query: 1006 -ERRDRELALRIAQSEAELISDEAQADLALRRNDGTRPKMTPEQMAKEMSEFLSRGPAV 1063
ER+ +EL R+ + +A + AL ++ EQ+ +E E + G V
Sbjct: 1848 LERQIQELRGRLGEEDAGARARHKMTIAALE----SKLAQAEEQLEQETRERILSGKLV 1902
Score = 42.4 bits (98), Expect = 0.003
Identities = 52/222 (23%), Positives = 97/222 (43%), Gaps = 24/222 (10%)
Query: 855 EVVSVLKDGKPEMNKQIKNLEISIDTLMAKIKSTMMTQE---QIQKEYDALVKSSEE--- 908
E L+ G+ + + E L K ++ + ++Q+E D E+
Sbjct: 1440 EEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQ 1499
Query: 909 LLSALQKKKQQ------EEEAERLRRIQEEMEKERKRREEDEK-----RRRKEEEERRMK 957
L+S L+KK+++ EE+A LR ++E E + RE + + R +EE+E R +
Sbjct: 1500 LVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREE 1559
Query: 958 LEME--AKRKQEEEERKKREDDEKRI-QAEVEAQLARQKEEESQQQAV-LEQERRDRELA 1013
LE + A R + E ++D K + + E ++A Q + + Q LE E E A
Sbjct: 1560 LERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDA 1619
Query: 1014 LRIAQSEAELISDEAQADLALRRNDGTRPKMTPEQMAKEMSE 1055
+ + + + + DL R G + Q+AK++ +
Sbjct: 1620 KLRLEVTVQALKTQHERDLQGRDEAGEERR---RQLAKQLRD 1658
Score = 41.6 bits (96), Expect = 0.005
Identities = 57/244 (23%), Positives = 114/244 (46%), Gaps = 34/244 (13%)
Query: 834 KPRIDGLVKVGTLKKRLDKFNEVVSVLKDGKPEMNKQIKNL--EISID-TLMAKIKS-TM 889
K +++G ++G L++ L++ +L D ++ Q+++L E+S + + AK +S
Sbjct: 1789 KRQLEG--RLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQ 1846
Query: 890 MTQEQIQK------EYDALVKSSEEL-LSALQKKKQQEEEA------ERL------RRIQ 930
+ QIQ+ E DA ++ ++ ++AL+ K Q EE ER+ RR +
Sbjct: 1847 QLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAE 1906
Query: 931 EEMEK-----ERKRREEDEKRRRKEEEERRMKLEMEAKRKQEEEERKKREDDEKRIQAEV 985
+ +++ E +RR D+ R + E+ R+K +++ + ++ EEE + + +R+Q E+
Sbjct: 1907 KRLKEVVLQVEEERRVADQLRDQLEKGNLRVK-QLKRQLEEAEEEASRAQAGRRRLQREL 1965
Query: 986 EAQLARQKEEESQQQAVLEQERRDRELAL--RIAQSEAELISDEAQADLALRRNDGTRPK 1043
E + E +++ L R L R + L A + A G+ P
Sbjct: 1966 E-DVTESAESMNREVTTLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEEAQPGSGPS 2024
Query: 1044 MTPE 1047
PE
Sbjct: 2025 PEPE 2028
>gi|118402590 myosin XV [Homo sapiens]
Length = 3530
Score = 438 bits (1126), Expect = e-122
Identities = 291/812 (35%), Positives = 429/812 (52%), Gaps = 87/812 (10%)
Query: 52 EEDSKKDVEDNCSLMYLNEATLLHNIKVRYSKDRIYTYVANILIAVNPYFDIPKIYSSEA 111
E+ + VED L L E T+L N+K+R+ ++ IYTY+ +IL++VNPY + IY E
Sbjct: 1217 EQHGEDGVEDMTQLEDLQETTVLSNLKIRFERNLIYTYIGSILVSVNPY-QMFGIYGPEQ 1275
Query: 112 IKSYQGKSLGTRPPHVFAIADKAFRDMKVLKMSQSIIVSGESGAGKTENTKFVLRYLTES 171
++ Y G++LG PPH+FA+A+ AF M K +Q II+SGESG+GKTE TK +LRYL
Sbjct: 1276 VQQYNGRALGENPPHLFAVANLAFAKMLDAKQNQCIIISGESGSGKTEATKLILRYLAAM 1335
Query: 172 YGTGQDIDD-RIVEANPLLEAFGNAKTVRNNNSSRFGKFVEIHFNEKSSVVGGFVSHYLL 230
+ + +I+EA PLLE+FGNAKTVRN+NSSRFGKFVEI F E + G S YLL
Sbjct: 1336 NQKREVMQQIKILEATPLLESFGNAKTVRNDNSSRFGKFVEI-FLEGGVISGAITSQYLL 1394
Query: 231 EKSRICVQGKEERNYHIFYRLCAGASEDIREKLHLSSPDNFRYLNRGCTRYFANKETDKQ 290
EKSRI Q K ERNYHIFY L AG +R+ L + + YLN+G A K
Sbjct: 1395 EKSRIVFQAKNERNYHIFYELLAGLPAQLRQAFSLQEAETYYYLNQGGNCEIAGKS---- 1450
Query: 291 ILQNRKSPEYLKAGSMKDPLLDDHGDFIRMCTAMKKIGLDDEEKLDLFRVVAGVLHLGNI 350
D DF R+ AM+ +G E++ +FR++A +LHLGN+
Sbjct: 1451 ----------------------DADDFRRLLAAMEVLGFSSEDQDSIFRILASILHLGNV 1488
Query: 351 DFEEAGSTSGGCNLKNKSAQSLEYCAELLGLDQDDLRVSLTTRVMLTTAGGTKGTVIKVP 410
FE+ T SA+ ++ AELL + + L+ ++T +V T I P
Sbjct: 1489 YFEKY-ETDAQEVASVVSAREIQAVAELLQISPEGLQKAITFKVTETMR-----EKIFTP 1542
Query: 411 LKVEQANNARDALAKTVYSHLFDHVVNRVNQCFPFETSSYFIGVLDIAGFEYFEHNSFEQ 470
L VE A +ARDA+AK +Y+ LF ++ RVN + I +LDI GFE NSFEQ
Sbjct: 1543 LTVESAVDARDAIAKVLYALLFSWLITRVNALVSPRQDTLSIAILDIYGFEDLSFNSFEQ 1602
Query: 471 FCINYCNEKLQQFFNERILKEEQELYQKEGLGVNEVHYVDNQDCIDLIEAKLVGILDILD 530
CINY NE LQ FN+ + +EEQE Y +E + E+ + DNQ CI+LI K GIL ILD
Sbjct: 1603 LCINYANENLQYLFNKIVFQEEQEEYIREQIDWQEITFADNQPCINLISLKPYGILRILD 1662
Query: 531 EENRLPQPSDQHFTSAVHQKHKDHFRLTIPRKSKLAVHRNIRDDEGFIIRHFAGAVCYET 590
++ PQ +D F H H + + K K+ + F I+H+AG V Y+
Sbjct: 1663 DQCCFPQATDHTFLQKCHYHHGAN---PLYSKPKMPLPE-------FTIKHYAGKVTYQV 1712
Query: 591 TQFVEKNNDALHMSLESLICESRDKFIRELFESSTNNNKDTKQKAGKLSFI-------SV 643
+F++KN+D + + L SR + + LF S++ + Q+ GK S + +V
Sbjct: 1713 HKFLDKNHDQVRQDVLDLFVRSRTRVVAHLF--SSHAPQAAPQRLGKSSSVTRLYKAHTV 1770
Query: 644 GNKFKTQLNLLLDKLRSTGASFIRCIKPNLKMTSHHFEGAQILSQLQCSGMVSVLDLMQG 703
KF+ L L++K+ F+RC+KPN K FE +++QL+ SG++ + + +
Sbjct: 1771 AAKFQQSLLDLVEKMERCNPLFMRCLKPNHKKEPGLFEPDVVMAQLRYSGVLETVRIRKE 1830
Query: 704 GYPSRASFHELYNMY------KKYMP---DKLARLDPRLFCKALFKALGLNENDYKFGLT 754
G+P R F + Y K +P D + RL CK + N Y+ G++
Sbjct: 1831 GFPVRLPFQGFIDRYCCLVALKHDLPANGDMCVSVLSRL-CKVM-------PNMYRVGVS 1882
Query: 755 KVFFRPGKFAEFDQIMKSDPDHLAELVKRVNHWLTCSRWKKVQWCSLSVIKLKNKIKYRA 814
K+F + + Q+++S +H+ L LT R + + L++KI
Sbjct: 1883 KLFLKEHLY----QLLESMREHVLNLAA-----LTLQRCLRGFFIKRRFRSLRHKI---- 1929
Query: 815 EACIKMQKTIRMWLCKRRHKPRIDGLVKVGTL 846
I +Q R +L ++R++ LVK +L
Sbjct: 1930 ---ILLQSRARGYLARQRYQQMRRSLVKFRSL 1958
>gi|194328685 myosin IB isoform 1 [Homo sapiens]
Length = 1136
Score = 433 bits (1114), Expect = e-121
Identities = 269/748 (35%), Positives = 405/748 (54%), Gaps = 50/748 (6%)
Query: 54 DSKKDVEDNCSLMYLNEATLLHNIKVRYSKDRIYTYVANILIAVNPYFDIPKIYSSEAIK 113
D+ V D L LNE T ++N+K R+ IYTY+ +++I+VNPY +P IYS E ++
Sbjct: 12 DNMIGVGDMVLLEPLNEETFINNLKKRFDHSEIYTYIGSVVISVNPYRSLP-IYSPEKVE 70
Query: 114 SYQGKSLGTRPPHVFAIADKAFRDMKVLKMSQSIIVSGESGAGKTENTKFVLRYLTESYG 173
Y+ ++ PH+FA++D+A+R ++ Q I+++GESGAGKTE +K V+ Y+ G
Sbjct: 71 EYRNRNFYELSPHIFALSDEAYRSLRDQDKDQCILITGESGAGKTEASKLVMSYVAAVCG 130
Query: 174 TGQDID---DRIVEANPLLEAFGNAKTVRNNNSSRFGKFVEIHFNEKSSVVGGFVSHYLL 230
G +++ ++++++NP+LEAFGNAKTVRN+NSSRFGK+++I F+ K +GG +S+YLL
Sbjct: 131 KGAEVNQVKEQLLQSNPVLEAFGNAKTVRNDNSSRFGKYMDIEFDFKGDPLGGVISNYLL 190
Query: 231 EKSRICVQGKEERNYHIFYRLCAGASEDIREKLHLSSPDNFRYLNRGCTRYFANKETDKQ 290
EKSR+ Q + ERN+H+FY+L +GASE++ KL L R +RY
Sbjct: 191 EKSRVVKQPRGERNFHVFYQLLSGASEELLNKLK---------LERDFSRY--------- 232
Query: 291 ILQNRKSPEYLKAGSMKDPLLDDHGDFIRMCTAMKKIGLDDEEKLDLFRVVAGVLHLGNI 350
YL S K +DD +F + AM+ +G D E + VVA VL LGNI
Sbjct: 233 --------NYLSLDSAKVNGVDDAANFRTVRNAMQIVGFMDHEAESVLAVVAAVLKLGNI 284
Query: 351 DFEEAGSTSGGCNLKNKSAQSLEYCAELLGLDQDDLRVSLTTRVMLTTAGGTKGTVIKVP 410
+F+ +G K K L+ EL G+DQ L + + R + K +
Sbjct: 285 EFKPESRVNGLDESKIKDKNELKEICELTGIDQSVLERAFSFRTV-----EAKQEKVSTT 339
Query: 411 LKVEQANNARDALAKTVYSHLFDHVVNRVNQCFPFETS--SYFIGVLDIAGFEYFEHNSF 468
L V QA ARDALAK +YS LF +VNR+N+ +T +GVLDI GFE FE NSF
Sbjct: 340 LNVAQAYYARDALAKNLYSRLFSWLVNRINESIKAQTKVRKKVMGVLDIYGFEIFEDNSF 399
Query: 469 EQFCINYCNEKLQQFFNERILKEEQELYQKEGLGVNEVHYVDNQDCIDLIEAKLVGILDI 528
EQF INYCNEKLQQ F E LKEEQE Y +E + + Y +N DLIE GIL +
Sbjct: 400 EQFIINYCNEKLQQIFIELTLKEEQEEYIREDIEWTHIDYFNNAIICDLIENNTNGILAM 459
Query: 529 LDEENRLP-QPSDQHFTSAVHQ--KHKDHFRLTIPRKSKLAVHRNIRDDEGFIIRHFAGA 585
LDEE P +D+ F ++Q HF + + S+ ++ F I+H+AG
Sbjct: 460 LDEECLRPGTVTDETFLEKLNQVCATHQHFESRMSKCSRFLNDTSL-PHSCFRIQHYAGK 518
Query: 586 VCYETTQFVEKNNDALHMSLESLICESRDKFIRELFESSTNNNKDTKQKAGKLSFISVGN 645
V Y+ FV+KNND L+ L + ++ I+ LF + K+ + G+
Sbjct: 519 VLYQVEGFVDKNNDLLYRDLSQAMWKASHALIKSLFPEGNPAKINLKRPP------TAGS 572
Query: 646 KFKTQLNLLLDKLRSTGASFIRCIKPNLKMTSHHFEGAQILSQLQCSGMVSVLDLMQGGY 705
+FK + L+ L++ ++IRCIKPN K +H F A + Q++ G++ + + + GY
Sbjct: 573 QFKASVATLMKNLQTKNPNYIRCIKPNDKKAAHIFNEALVCHQIRYLGLLENVRVRRAGY 632
Query: 706 PSRASFHELYNMYKKYMPDKLA--RLDPRLFCKALFKALGLNENDYKFGLTKVFFR-PGK 762
R ++ YK + R + LF L + +Y FG +K+F R P
Sbjct: 633 AFRQAYEPCLERYKMLCKQTWPHWKGPARSGVEVLFNELEIPVEEYSFGRSKIFIRNPRT 692
Query: 763 FAEFDQIMKSDPDHLAELVKRVNHWLTC 790
+ + + K + LA L++++ C
Sbjct: 693 LFKLEDLRKQRLEDLATLIQKIYRGWKC 720
>gi|44889481 myosin IB isoform 2 [Homo sapiens]
Length = 1078
Score = 433 bits (1114), Expect = e-121
Identities = 269/748 (35%), Positives = 405/748 (54%), Gaps = 50/748 (6%)
Query: 54 DSKKDVEDNCSLMYLNEATLLHNIKVRYSKDRIYTYVANILIAVNPYFDIPKIYSSEAIK 113
D+ V D L LNE T ++N+K R+ IYTY+ +++I+VNPY +P IYS E ++
Sbjct: 12 DNMIGVGDMVLLEPLNEETFINNLKKRFDHSEIYTYIGSVVISVNPYRSLP-IYSPEKVE 70
Query: 114 SYQGKSLGTRPPHVFAIADKAFRDMKVLKMSQSIIVSGESGAGKTENTKFVLRYLTESYG 173
Y+ ++ PH+FA++D+A+R ++ Q I+++GESGAGKTE +K V+ Y+ G
Sbjct: 71 EYRNRNFYELSPHIFALSDEAYRSLRDQDKDQCILITGESGAGKTEASKLVMSYVAAVCG 130
Query: 174 TGQDID---DRIVEANPLLEAFGNAKTVRNNNSSRFGKFVEIHFNEKSSVVGGFVSHYLL 230
G +++ ++++++NP+LEAFGNAKTVRN+NSSRFGK+++I F+ K +GG +S+YLL
Sbjct: 131 KGAEVNQVKEQLLQSNPVLEAFGNAKTVRNDNSSRFGKYMDIEFDFKGDPLGGVISNYLL 190
Query: 231 EKSRICVQGKEERNYHIFYRLCAGASEDIREKLHLSSPDNFRYLNRGCTRYFANKETDKQ 290
EKSR+ Q + ERN+H+FY+L +GASE++ KL L R +RY
Sbjct: 191 EKSRVVKQPRGERNFHVFYQLLSGASEELLNKLK---------LERDFSRY--------- 232
Query: 291 ILQNRKSPEYLKAGSMKDPLLDDHGDFIRMCTAMKKIGLDDEEKLDLFRVVAGVLHLGNI 350
YL S K +DD +F + AM+ +G D E + VVA VL LGNI
Sbjct: 233 --------NYLSLDSAKVNGVDDAANFRTVRNAMQIVGFMDHEAESVLAVVAAVLKLGNI 284
Query: 351 DFEEAGSTSGGCNLKNKSAQSLEYCAELLGLDQDDLRVSLTTRVMLTTAGGTKGTVIKVP 410
+F+ +G K K L+ EL G+DQ L + + R + K +
Sbjct: 285 EFKPESRVNGLDESKIKDKNELKEICELTGIDQSVLERAFSFRTV-----EAKQEKVSTT 339
Query: 411 LKVEQANNARDALAKTVYSHLFDHVVNRVNQCFPFETS--SYFIGVLDIAGFEYFEHNSF 468
L V QA ARDALAK +YS LF +VNR+N+ +T +GVLDI GFE FE NSF
Sbjct: 340 LNVAQAYYARDALAKNLYSRLFSWLVNRINESIKAQTKVRKKVMGVLDIYGFEIFEDNSF 399
Query: 469 EQFCINYCNEKLQQFFNERILKEEQELYQKEGLGVNEVHYVDNQDCIDLIEAKLVGILDI 528
EQF INYCNEKLQQ F E LKEEQE Y +E + + Y +N DLIE GIL +
Sbjct: 400 EQFIINYCNEKLQQIFIELTLKEEQEEYIREDIEWTHIDYFNNAIICDLIENNTNGILAM 459
Query: 529 LDEENRLP-QPSDQHFTSAVHQ--KHKDHFRLTIPRKSKLAVHRNIRDDEGFIIRHFAGA 585
LDEE P +D+ F ++Q HF + + S+ ++ F I+H+AG
Sbjct: 460 LDEECLRPGTVTDETFLEKLNQVCATHQHFESRMSKCSRFLNDTSL-PHSCFRIQHYAGK 518
Query: 586 VCYETTQFVEKNNDALHMSLESLICESRDKFIRELFESSTNNNKDTKQKAGKLSFISVGN 645
V Y+ FV+KNND L+ L + ++ I+ LF + K+ + G+
Sbjct: 519 VLYQVEGFVDKNNDLLYRDLSQAMWKASHALIKSLFPEGNPAKINLKRPP------TAGS 572
Query: 646 KFKTQLNLLLDKLRSTGASFIRCIKPNLKMTSHHFEGAQILSQLQCSGMVSVLDLMQGGY 705
+FK + L+ L++ ++IRCIKPN K +H F A + Q++ G++ + + + GY
Sbjct: 573 QFKASVATLMKNLQTKNPNYIRCIKPNDKKAAHIFNEALVCHQIRYLGLLENVRVRRAGY 632
Query: 706 PSRASFHELYNMYKKYMPDKLA--RLDPRLFCKALFKALGLNENDYKFGLTKVFFR-PGK 762
R ++ YK + R + LF L + +Y FG +K+F R P
Sbjct: 633 AFRQAYEPCLERYKMLCKQTWPHWKGPARSGVEVLFNELEIPVEEYSFGRSKIFIRNPRT 692
Query: 763 FAEFDQIMKSDPDHLAELVKRVNHWLTC 790
+ + + K + LA L++++ C
Sbjct: 693 LFKLEDLRKQRLEDLATLIQKIYRGWKC 720
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.134 0.386
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 47,510,796
Number of Sequences: 37866
Number of extensions: 2236413
Number of successful extensions: 63012
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1204
Number of HSP's successfully gapped in prelim test: 1062
Number of HSP's that attempted gapping in prelim test: 14038
Number of HSP's gapped (non-prelim): 16138
length of query: 1285
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1171
effective length of database: 13,930,794
effective search space: 16312959774
effective search space used: 16312959774
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.