Search of human proteins with 89903018

Search of human proteins with 89903018

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|89903018 cell cycle related kinase isoform 3 [Homo sapiens]
         (346 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|89903018 cell cycle related kinase isoform 3 [Homo sapiens]        707   0.0  
gi|30795215 cell cycle related kinase isoform 2 [Homo sapiens]        648   0.0  
gi|30795255 cell cycle related kinase isoform 1 [Homo sapiens]        639   0.0  
gi|4557439 cyclin-dependent kinase 3 [Homo sapiens]                   260   1e-69
gi|16936528 cyclin-dependent kinase 2 isoform 1 [Homo sapiens]        244   6e-65
gi|4502743 cyclin-dependent kinase 7 [Homo sapiens]                   243   2e-64
gi|4502709 cell division cycle 2 isoform 1 [Homo sapiens]             242   3e-64
gi|195927041 cell division cycle 2 isoform 3 [Homo sapiens]           240   1e-63
gi|4826675 cyclin-dependent kinase 5 [Homo sapiens]                   237   1e-62
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof...   234   7e-62
gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isof...   234   7e-62
gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof...   234   7e-62
gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof...   234   7e-62
gi|16332360 cell division cycle 2-like 1 (PITSLRE proteins) isof...   234   7e-62
gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isof...   234   7e-62
gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]    233   1e-61
gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]    233   1e-61
gi|145309302 cell division cycle 2-like 5 isoform 1 [Homo sapiens]    232   4e-61
gi|145309300 cell division cycle 2-like 5 isoform 2 [Homo sapiens]    232   4e-61
gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2...   231   9e-61
gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1...   231   9e-61
gi|148596926 cyclin-dependent kinase 10 isoform a [Homo sapiens]      215   5e-56
gi|47078233 PCTAIRE protein kinase 3 isoform a [Homo sapiens]         215   5e-56
gi|47078231 PCTAIRE protein kinase 3 isoform b [Homo sapiens]         215   5e-56
gi|47078229 PCTAIRE protein kinase 3 isoform b [Homo sapiens]         215   5e-56
gi|4502747 cyclin-dependent kinase 9 [Homo sapiens]                   214   7e-56
gi|37595545 PCTAIRE protein kinase 2 [Homo sapiens]                   211   6e-55
gi|83367069 cyclin-dependent kinase-like 5 [Homo sapiens]             206   2e-53
gi|4507281 cyclin-dependent kinase-like 5 [Homo sapiens]              206   2e-53
gi|197333744 PCTAIRE protein kinase 1 isoform 2 [Homo sapiens]        199   3e-51

>gi|89903018 cell cycle related kinase isoform 3 [Homo sapiens]
          Length = 346

 Score =  707 bits (1826), Expect = 0.0
 Identities = 346/346 (100%), Positives = 346/346 (100%)

Query: 1   MDQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGFPNQALREIKALQEMED 60
           MDQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGFPNQALREIKALQEMED
Sbjct: 1   MDQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGFPNQALREIKALQEMED 60

Query: 61  NQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQMLLKGVAFCHA 120
           NQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQMLLKGVAFCHA
Sbjct: 61  NQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQMLLKGVAFCHA 120

Query: 121 NNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATRWYRAPELLYGARQ 180
           NNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATRWYRAPELLYGARQ
Sbjct: 121 NNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATRWYRAPELLYGARQ 180

Query: 181 YDQGVDLWSVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQVWPELTELPDYNKI 240
           YDQGVDLWSVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQVWPELTELPDYNKI
Sbjct: 181 YDQGVDLWSVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQVWPELTELPDYNKI 240

Query: 241 SFKEQVPMPLEEVLPDVSPQALDLLGQFLLYPPHQRIAASKALLHQYFFTAPLPAHPSEL 300
           SFKEQVPMPLEEVLPDVSPQALDLLGQFLLYPPHQRIAASKALLHQYFFTAPLPAHPSEL
Sbjct: 241 SFKEQVPMPLEEVLPDVSPQALDLLGQFLLYPPHQRIAASKALLHQYFFTAPLPAHPSEL 300

Query: 301 PIPQRLGGPAPKAHPGPPHIHDFHVDRPLEESLLNPELIRPFILEG 346
           PIPQRLGGPAPKAHPGPPHIHDFHVDRPLEESLLNPELIRPFILEG
Sbjct: 301 PIPQRLGGPAPKAHPGPPHIHDFHVDRPLEESLLNPELIRPFILEG 346


>gi|30795215 cell cycle related kinase isoform 2 [Homo sapiens]
          Length = 325

 Score =  648 bits (1671), Expect = 0.0
 Identities = 325/346 (93%), Positives = 325/346 (93%), Gaps = 21/346 (6%)

Query: 1   MDQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGFPNQALREIKALQEMED 60
           MDQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGFPNQALREIKALQEMED
Sbjct: 1   MDQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGFPNQALREIKALQEMED 60

Query: 61  NQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQMLLKGVAFCHA 120
           NQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQMLLKGVAFCHA
Sbjct: 61  NQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQMLLKGVAFCHA 120

Query: 121 NNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATRWYRAPELLYGARQ 180
           NNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATR             
Sbjct: 121 NNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATR------------- 167

Query: 181 YDQGVDLWSVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQVWPELTELPDYNKI 240
                   SVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQVWPELTELPDYNKI
Sbjct: 168 --------SVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQVWPELTELPDYNKI 219

Query: 241 SFKEQVPMPLEEVLPDVSPQALDLLGQFLLYPPHQRIAASKALLHQYFFTAPLPAHPSEL 300
           SFKEQVPMPLEEVLPDVSPQALDLLGQFLLYPPHQRIAASKALLHQYFFTAPLPAHPSEL
Sbjct: 220 SFKEQVPMPLEEVLPDVSPQALDLLGQFLLYPPHQRIAASKALLHQYFFTAPLPAHPSEL 279

Query: 301 PIPQRLGGPAPKAHPGPPHIHDFHVDRPLEESLLNPELIRPFILEG 346
           PIPQRLGGPAPKAHPGPPHIHDFHVDRPLEESLLNPELIRPFILEG
Sbjct: 280 PIPQRLGGPAPKAHPGPPHIHDFHVDRPLEESLLNPELIRPFILEG 325


>gi|30795255 cell cycle related kinase isoform 1 [Homo sapiens]
          Length = 338

 Score =  639 bits (1647), Expect = 0.0
 Identities = 325/359 (90%), Positives = 325/359 (90%), Gaps = 34/359 (9%)

Query: 1   MDQYCILGRIGEGAHGIVFKAKHVE-------------TGEIVALKKVALRRLEDGFPNQ 47
           MDQYCILGRIGEGAHGIVFKAKHVE             TGEIVALKKVALRRLEDGFPNQ
Sbjct: 1   MDQYCILGRIGEGAHGIVFKAKHVEPRVGWQCLPSILQTGEIVALKKVALRRLEDGFPNQ 60

Query: 48  ALREIKALQEMEDNQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSY 107
           ALREIKALQEMEDNQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSY
Sbjct: 61  ALREIKALQEMEDNQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSY 120

Query: 108 LQMLLKGVAFCHANNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATR 167
           LQMLLKGVAFCHANNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATR
Sbjct: 121 LQMLLKGVAFCHANNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATR 180

Query: 168 WYRAPELLYGARQYDQGVDLWSVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQV 227
                                SVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQV
Sbjct: 181 ---------------------SVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQV 219

Query: 228 WPELTELPDYNKISFKEQVPMPLEEVLPDVSPQALDLLGQFLLYPPHQRIAASKALLHQY 287
           WPELTELPDYNKISFKEQVPMPLEEVLPDVSPQALDLLGQFLLYPPHQRIAASKALLHQY
Sbjct: 220 WPELTELPDYNKISFKEQVPMPLEEVLPDVSPQALDLLGQFLLYPPHQRIAASKALLHQY 279

Query: 288 FFTAPLPAHPSELPIPQRLGGPAPKAHPGPPHIHDFHVDRPLEESLLNPELIRPFILEG 346
           FFTAPLPAHPSELPIPQRLGGPAPKAHPGPPHIHDFHVDRPLEESLLNPELIRPFILEG
Sbjct: 280 FFTAPLPAHPSELPIPQRLGGPAPKAHPGPPHIHDFHVDRPLEESLLNPELIRPFILEG 338


>gi|4557439 cyclin-dependent kinase 3 [Homo sapiens]
          Length = 305

 Score =  260 bits (665), Expect = 1e-69
 Identities = 139/306 (45%), Positives = 199/306 (65%), Gaps = 5/306 (1%)

Query: 1   MDQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGFPNQALREIKALQEMED 60
           MD +  + +IGEG +G+V+KAK+ ETG++VALKK+ L    +G P+ A+REI  L+E++ 
Sbjct: 1   MDMFQKVEKIGEGTYGVVYKAKNRETGQLVALKKIRLDLEMEGVPSTAIREISLLKELK- 59

Query: 61  NQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQ-RPLAQAQVKSYLQMLLKGVAFCH 119
           +  +V+L  V  +     L FEF+  DL + +       L    +KSYL  LL+GV+FCH
Sbjct: 60  HPNIVRLLDVVHNERKLYLVFEFLSQDLKKYMDSTPGSELPLHLIKSYLFQLLQGVSFCH 119

Query: 120 ANNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATRWYRAPELLYGAR 179
           ++ ++HRDLKP NLLI+  G +K+ADFGLAR F     R YTH+V T WYRAPE+L G++
Sbjct: 120 SHRVIHRDLKPQNLLINELGAIKLADFGLARAFGVP-LRTYTHEVVTLWYRAPEILLGSK 178

Query: 180 QYDQGVDLWSVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQVWPELTELPDYNK 239
            Y   VD+WS+GCI  E++    LFPG ++I+QL  + R+LGTP+   WP +T+LPDY K
Sbjct: 179 FYTTAVDIWSIGCIFAEMVTRKALFPGDSEIDQLFRIFRMLGTPSEDTWPGVTQLPDY-K 237

Query: 240 ISFKEQVPMPLEEVLPDVSPQALDLLGQFLLYPPHQRIAASKALLHQYFFTAPLPAHPSE 299
            SF +     LEE++P++ P+  DLL Q L Y P QRI A  AL H Y F++P P+  + 
Sbjct: 238 GSFPKWTRKGLEEIVPNLEPEGRDLLMQLLQYDPSQRITAKTALAHPY-FSSPEPSPAAR 296

Query: 300 LPIPQR 305
             + QR
Sbjct: 297 QYVLQR 302


>gi|16936528 cyclin-dependent kinase 2 isoform 1 [Homo sapiens]
          Length = 298

 Score =  244 bits (624), Expect = 6e-65
 Identities = 130/297 (43%), Positives = 187/297 (62%), Gaps = 6/297 (2%)

Query: 1   MDQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGFPNQALREIKALQEMED 60
           M+ +  + +IGEG +G+V+KA++  TGE+VALKK+ L    +G P+ A+REI  L+E+ +
Sbjct: 1   MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKEL-N 59

Query: 61  NQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVV-RHAQRPLAQAQVKSYLQMLLKGVAFCH 119
           +  +V+L  V        L FEF+  DL + +   A   +    +KSYL  LL+G+AFCH
Sbjct: 60  HPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCH 119

Query: 120 ANNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATRWYRAPELLYGAR 179
           ++ ++HRDLKP NLLI+  G +K+ADFGLAR F     R YTH+V T WYRAPE+L G +
Sbjct: 120 SHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVP-VRTYTHEVVTLWYRAPEILLGCK 178

Query: 180 QYDQGVDLWSVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQVWPELTELPDYNK 239
            Y   VD+WS+GCI  E++    LFPG ++I+QL  + R LGTP+  VWP +T +PDY K
Sbjct: 179 YYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDY-K 237

Query: 240 ISFKEQVPMPLEEVLPDVSPQALDLLGQFLLYPPHQRIAASKALLHQYF--FTAPLP 294
            SF +       +V+P +      LL Q L Y P++RI+A  AL H +F   T P+P
Sbjct: 238 PSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP 294


>gi|4502743 cyclin-dependent kinase 7 [Homo sapiens]
          Length = 346

 Score =  243 bits (619), Expect = 2e-64
 Identities = 130/304 (42%), Positives = 182/304 (59%), Gaps = 7/304 (2%)

Query: 3   QYCILGRIGEGAHGIVFKAKHVETGEIVALKKVAL---RRLEDGFPNQALREIKALQEME 59
           +Y  L  +GEG    V+KA+   T +IVA+KK+ L      +DG    ALREIK LQE+ 
Sbjct: 11  RYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELS 70

Query: 60  DNQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQMLLKGVAFCH 119
            +  ++ L   F H     L F+FM +DL  +++     L  + +K+Y+ M L+G+ + H
Sbjct: 71  -HPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLH 129

Query: 120 ANNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATRWYRAPELLYGAR 179
            + I+HRDLKP NLL+  +G LK+ADFGLA+ F    +R YTHQV TRWYRAPELL+GAR
Sbjct: 130 QHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSP-NRAYTHQVVTRWYRAPELLFGAR 188

Query: 180 QYDQGVDLWSVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQVWPELTELPDYNK 239
            Y  GVD+W+VGCI+ ELL   P  PG +D++QL  +   LGTP  + WP++  LPDY  
Sbjct: 189 MYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDY-- 246

Query: 240 ISFKEQVPMPLEEVLPDVSPQALDLLGQFLLYPPHQRIAASKALLHQYFFTAPLPAHPSE 299
           ++FK    +PL  +        LDL+    L+ P  RI A++AL  +YF   P P    +
Sbjct: 247 VTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQ 306

Query: 300 LPIP 303
           LP P
Sbjct: 307 LPRP 310


>gi|4502709 cell division cycle 2 isoform 1 [Homo sapiens]
          Length = 297

 Score =  242 bits (618), Expect = 3e-64
 Identities = 125/290 (43%), Positives = 181/290 (62%), Gaps = 5/290 (1%)

Query: 1   MDQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGFPNQALREIKALQEMED 60
           M+ Y  + +IGEG +G+V+K +H  TG++VA+KK+ L   E+G P+ A+REI  L+E+  
Sbjct: 1   MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELR- 59

Query: 61  NQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQ--RPLAQAQVKSYLQMLLKGVAFC 118
           +  +V L+ V        L FEF+  DL + +      + +  + VKSYL  +L+G+ FC
Sbjct: 60  HPNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFC 119

Query: 119 HANNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATRWYRAPELLYGA 178
           H+  ++HRDLKP NLLI   G +K+ADFGLAR F     R+YTH+V T WYR+PE+L G+
Sbjct: 120 HSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIP-IRVYTHEVVTLWYRSPEVLLGS 178

Query: 179 RQYDQGVDLWSVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQVWPELTELPDYN 238
            +Y   VD+WS+G I  EL    PLF G ++I+QL  + R LGTPN +VWPE+  L DY 
Sbjct: 179 ARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDY- 237

Query: 239 KISFKEQVPMPLEEVLPDVSPQALDLLGQFLLYPPHQRIAASKALLHQYF 288
           K +F +  P  L   + ++    LDLL + L+Y P +RI+   AL H YF
Sbjct: 238 KNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYF 287


>gi|195927041 cell division cycle 2 isoform 3 [Homo sapiens]
          Length = 297

 Score =  240 bits (613), Expect = 1e-63
 Identities = 124/290 (42%), Positives = 180/290 (62%), Gaps = 5/290 (1%)

Query: 1   MDQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGFPNQALREIKALQEMED 60
           M+ Y  + +IGEG +G+V+K +H  TG++VA+KK+ L   E+G P+ A+REI  L+E+  
Sbjct: 1   MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELR- 59

Query: 61  NQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQ--RPLAQAQVKSYLQMLLKGVAFC 118
           +  +V L+ V        L FEF+  DL + +      + +  + VKSYL  +L+G+ FC
Sbjct: 60  HPNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFC 119

Query: 119 HANNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATRWYRAPELLYGA 178
           H+  ++HRDLKP NLLI   G +K+ADFGLAR F     R+YTH+  T WYR+PE+L G+
Sbjct: 120 HSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIP-IRVYTHEAITLWYRSPEVLLGS 178

Query: 179 RQYDQGVDLWSVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQVWPELTELPDYN 238
            +Y   VD+WS+G I  EL    PLF G ++I+QL  + R LGTPN +VWPE+  L DY 
Sbjct: 179 ARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDY- 237

Query: 239 KISFKEQVPMPLEEVLPDVSPQALDLLGQFLLYPPHQRIAASKALLHQYF 288
           K +F +  P  L   + ++    LDLL + L+Y P +RI+   AL H YF
Sbjct: 238 KNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYF 287


>gi|4826675 cyclin-dependent kinase 5 [Homo sapiens]
          Length = 292

 Score =  237 bits (605), Expect = 1e-62
 Identities = 133/289 (46%), Positives = 178/289 (61%), Gaps = 4/289 (1%)

Query: 1   MDQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGFPNQALREIKALQEMED 60
           M +Y  L +IGEG +G VFKAK+ ET EIVALK+V L   ++G P+ ALREI  L+E++ 
Sbjct: 1   MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELK- 59

Query: 61  NQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQMLLKGVAFCHA 120
           ++ +V+L  V        L FEF   DL +        L    VKS+L  LLKG+ FCH+
Sbjct: 60  HKNIVRLHDVLHSDKKLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCHS 119

Query: 121 NNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATRWYRAPELLYGARQ 180
            N++HRDLKP NLLI+ +G+LK+ADFGLAR F     R Y+ +V T WYR P++L+GA+ 
Sbjct: 120 RNVLHRDLKPQNLLINRNGELKLADFGLARAFGIP-VRCYSAEVVTLWYRPPDVLFGAKL 178

Query: 181 YDQGVDLWSVGCIMGELLN-GSPLFPGKNDIEQLCYVLRILGTPNPQVWPELTELPDYNK 239
           Y   +D+WS GCI  EL N G PLFPG +  +QL  + R+LGTP  + WP +T+LPDY  
Sbjct: 179 YSTSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPSMTKLPDYKP 238

Query: 240 ISFKEQVPMPLEEVLPDVSPQALDLLGQFLLYPPHQRIAASKALLHQYF 288
                     L  V+P ++    DLL   L   P QRI+A +AL H YF
Sbjct: 239 YPM-YPATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPYF 286


>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           9 [Homo sapiens]
          Length = 771

 Score =  234 bits (598), Expect = 7e-62
 Identities = 127/303 (41%), Positives = 185/303 (61%), Gaps = 3/303 (0%)

Query: 1   MDQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGFPNQALREIKA-LQEME 59
           ++++  L RI EG +G+V++AK  +T EIVALK++ + + ++GFP  +LREI   L+   
Sbjct: 411 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 470

Query: 60  DNQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQMLLKGVAFCH 119
            N   V+   V  +     +   ++  DL  ++   ++P    +VK+ +  LL+GV   H
Sbjct: 471 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLH 530

Query: 120 ANNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATRWYRAPELLYGAR 179
            N I+HRDLK +NLL+S +G LK+ DFGLAR +     + YT  V T WYRAPELL GA+
Sbjct: 531 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSP-LKAYTPVVVTLWYRAPELLLGAK 589

Query: 180 QYDQGVDLWSVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQVWPELTELPDYNK 239
           +Y   VD+WSVGCI GELL   PLFPGK++I+Q+  V + LGTP+ ++WP  +ELP   K
Sbjct: 590 EYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKK 649

Query: 240 ISFKEQVPMPLEEVLPD-VSPQALDLLGQFLLYPPHQRIAASKALLHQYFFTAPLPAHPS 298
           ++F E     L +     +S Q  DL+ +FL Y P +RI+A   L H+YF   PLP  PS
Sbjct: 650 MTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPS 709

Query: 299 ELP 301
             P
Sbjct: 710 MFP 712


>gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           8 [Homo sapiens]
          Length = 780

 Score =  234 bits (598), Expect = 7e-62
 Identities = 127/303 (41%), Positives = 185/303 (61%), Gaps = 3/303 (0%)

Query: 1   MDQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGFPNQALREIKA-LQEME 59
           ++++  L RI EG +G+V++AK  +T EIVALK++ + + ++GFP  +LREI   L+   
Sbjct: 420 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 479

Query: 60  DNQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQMLLKGVAFCH 119
            N   V+   V  +     +   ++  DL  ++   ++P    +VK+ +  LL+GV   H
Sbjct: 480 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLH 539

Query: 120 ANNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATRWYRAPELLYGAR 179
            N I+HRDLK +NLL+S +G LK+ DFGLAR +     + YT  V T WYRAPELL GA+
Sbjct: 540 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSP-LKAYTPVVVTLWYRAPELLLGAK 598

Query: 180 QYDQGVDLWSVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQVWPELTELPDYNK 239
           +Y   VD+WSVGCI GELL   PLFPGK++I+Q+  V + LGTP+ ++WP  +ELP   K
Sbjct: 599 EYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKK 658

Query: 240 ISFKEQVPMPLEEVLPD-VSPQALDLLGQFLLYPPHQRIAASKALLHQYFFTAPLPAHPS 298
           ++F E     L +     +S Q  DL+ +FL Y P +RI+A   L H+YF   PLP  PS
Sbjct: 659 MTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPS 718

Query: 299 ELP 301
             P
Sbjct: 719 MFP 721


>gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           5 [Homo sapiens]
          Length = 748

 Score =  234 bits (598), Expect = 7e-62
 Identities = 127/303 (41%), Positives = 185/303 (61%), Gaps = 3/303 (0%)

Query: 1   MDQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGFPNQALREIKA-LQEME 59
           ++++  L RI EG +G+V++AK  +T EIVALK++ + + ++GFP  +LREI   L+   
Sbjct: 388 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 447

Query: 60  DNQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQMLLKGVAFCH 119
            N   V+   V  +     +   ++  DL  ++   ++P    +VK+ +  LL+GV   H
Sbjct: 448 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLH 507

Query: 120 ANNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATRWYRAPELLYGAR 179
            N I+HRDLK +NLL+S +G LK+ DFGLAR +     + YT  V T WYRAPELL GA+
Sbjct: 508 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSP-LKAYTPVVVTLWYRAPELLLGAK 566

Query: 180 QYDQGVDLWSVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQVWPELTELPDYNK 239
           +Y   VD+WSVGCI GELL   PLFPGK++I+Q+  V + LGTP+ ++WP  +ELP   K
Sbjct: 567 EYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKK 626

Query: 240 ISFKEQVPMPLEEVLPD-VSPQALDLLGQFLLYPPHQRIAASKALLHQYFFTAPLPAHPS 298
           ++F E     L +     +S Q  DL+ +FL Y P +RI+A   L H+YF   PLP  PS
Sbjct: 627 MTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPS 686

Query: 299 ELP 301
             P
Sbjct: 687 MFP 689


>gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           4 [Homo sapiens]
          Length = 737

 Score =  234 bits (598), Expect = 7e-62
 Identities = 127/303 (41%), Positives = 185/303 (61%), Gaps = 3/303 (0%)

Query: 1   MDQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGFPNQALREIKA-LQEME 59
           ++++  L RI EG +G+V++AK  +T EIVALK++ + + ++GFP  +LREI   L+   
Sbjct: 377 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 436

Query: 60  DNQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQMLLKGVAFCH 119
            N   V+   V  +     +   ++  DL  ++   ++P    +VK+ +  LL+GV   H
Sbjct: 437 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLH 496

Query: 120 ANNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATRWYRAPELLYGAR 179
            N I+HRDLK +NLL+S +G LK+ DFGLAR +     + YT  V T WYRAPELL GA+
Sbjct: 497 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSP-LKAYTPVVVTLWYRAPELLLGAK 555

Query: 180 QYDQGVDLWSVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQVWPELTELPDYNK 239
           +Y   VD+WSVGCI GELL   PLFPGK++I+Q+  V + LGTP+ ++WP  +ELP   K
Sbjct: 556 EYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKK 615

Query: 240 ISFKEQVPMPLEEVLPD-VSPQALDLLGQFLLYPPHQRIAASKALLHQYFFTAPLPAHPS 298
           ++F E     L +     +S Q  DL+ +FL Y P +RI+A   L H+YF   PLP  PS
Sbjct: 616 MTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPS 675

Query: 299 ELP 301
             P
Sbjct: 676 MFP 678


>gi|16332360 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           3 [Homo sapiens]
          Length = 526

 Score =  234 bits (598), Expect = 7e-62
 Identities = 127/303 (41%), Positives = 185/303 (61%), Gaps = 3/303 (0%)

Query: 1   MDQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGFPNQALREIKA-LQEME 59
           ++++  L RI EG +G+V++AK  +T EIVALK++ + + ++GFP  +LREI   L+   
Sbjct: 166 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 225

Query: 60  DNQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQMLLKGVAFCH 119
            N   V+   V  +     +   ++  DL  ++   ++P    +VK+ +  LL+GV   H
Sbjct: 226 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLH 285

Query: 120 ANNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATRWYRAPELLYGAR 179
            N I+HRDLK +NLL+S +G LK+ DFGLAR +     + YT  V T WYRAPELL GA+
Sbjct: 286 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSP-LKAYTPVVVTLWYRAPELLLGAK 344

Query: 180 QYDQGVDLWSVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQVWPELTELPDYNK 239
           +Y   VD+WSVGCI GELL   PLFPGK++I+Q+  V + LGTP+ ++WP  +ELP   K
Sbjct: 345 EYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKK 404

Query: 240 ISFKEQVPMPLEEVLPD-VSPQALDLLGQFLLYPPHQRIAASKALLHQYFFTAPLPAHPS 298
           ++F E     L +     +S Q  DL+ +FL Y P +RI+A   L H+YF   PLP  PS
Sbjct: 405 MTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPS 464

Query: 299 ELP 301
             P
Sbjct: 465 MFP 467


>gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           2 [Homo sapiens]
          Length = 782

 Score =  234 bits (598), Expect = 7e-62
 Identities = 127/303 (41%), Positives = 185/303 (61%), Gaps = 3/303 (0%)

Query: 1   MDQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGFPNQALREIKA-LQEME 59
           ++++  L RI EG +G+V++AK  +T EIVALK++ + + ++GFP  +LREI   L+   
Sbjct: 422 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 481

Query: 60  DNQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQMLLKGVAFCH 119
            N   V+   V  +     +   ++  DL  ++   ++P    +VK+ +  LL+GV   H
Sbjct: 482 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLH 541

Query: 120 ANNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATRWYRAPELLYGAR 179
            N I+HRDLK +NLL+S +G LK+ DFGLAR +     + YT  V T WYRAPELL GA+
Sbjct: 542 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSP-LKAYTPVVVTLWYRAPELLLGAK 600

Query: 180 QYDQGVDLWSVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQVWPELTELPDYNK 239
           +Y   VD+WSVGCI GELL   PLFPGK++I+Q+  V + LGTP+ ++WP  +ELP   K
Sbjct: 601 EYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKK 660

Query: 240 ISFKEQVPMPLEEVLPD-VSPQALDLLGQFLLYPPHQRIAASKALLHQYFFTAPLPAHPS 298
           ++F E     L +     +S Q  DL+ +FL Y P +RI+A   L H+YF   PLP  PS
Sbjct: 661 MTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPS 720

Query: 299 ELP 301
             P
Sbjct: 721 MFP 723


>gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]
          Length = 770

 Score =  233 bits (595), Expect = 1e-61
 Identities = 126/303 (41%), Positives = 185/303 (61%), Gaps = 3/303 (0%)

Query: 1   MDQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGFPNQALREIKA-LQEME 59
           ++++  L RI EG +G+V++AK  +T EIVALK++ + + ++GFP  +LREI   L+   
Sbjct: 410 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 469

Query: 60  DNQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQMLLKGVAFCH 119
            N   V+   V  +     +   ++  DL  ++   ++P    +VK+ +  LL+GV   H
Sbjct: 470 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLH 529

Query: 120 ANNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATRWYRAPELLYGAR 179
            N I+HRDLK +NLL+S +G LK+ DFGLAR +     + YT  V T+WYRAPELL GA+
Sbjct: 530 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSP-LKAYTPVVVTQWYRAPELLLGAK 588

Query: 180 QYDQGVDLWSVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQVWPELTELPDYNK 239
           +Y   VD+WSVGCI GELL   PLFPG ++I+Q+  V + LGTP+ ++WP  +ELP   K
Sbjct: 589 EYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKK 648

Query: 240 ISFKEQVPMPLEEVLPD-VSPQALDLLGQFLLYPPHQRIAASKALLHQYFFTAPLPAHPS 298
           ++F E     L +     +S Q  DL+ +FL Y P +RI+A   L H+YF   PLP  PS
Sbjct: 649 MTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPS 708

Query: 299 ELP 301
             P
Sbjct: 709 MFP 711


>gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]
          Length = 780

 Score =  233 bits (595), Expect = 1e-61
 Identities = 126/303 (41%), Positives = 185/303 (61%), Gaps = 3/303 (0%)

Query: 1   MDQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGFPNQALREIKA-LQEME 59
           ++++  L RI EG +G+V++AK  +T EIVALK++ + + ++GFP  +LREI   L+   
Sbjct: 420 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 479

Query: 60  DNQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQMLLKGVAFCH 119
            N   V+   V  +     +   ++  DL  ++   ++P    +VK+ +  LL+GV   H
Sbjct: 480 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLH 539

Query: 120 ANNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATRWYRAPELLYGAR 179
            N I+HRDLK +NLL+S +G LK+ DFGLAR +     + YT  V T+WYRAPELL GA+
Sbjct: 540 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSP-LKAYTPVVVTQWYRAPELLLGAK 598

Query: 180 QYDQGVDLWSVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQVWPELTELPDYNK 239
           +Y   VD+WSVGCI GELL   PLFPG ++I+Q+  V + LGTP+ ++WP  +ELP   K
Sbjct: 599 EYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKK 658

Query: 240 ISFKEQVPMPLEEVLPD-VSPQALDLLGQFLLYPPHQRIAASKALLHQYFFTAPLPAHPS 298
           ++F E     L +     +S Q  DL+ +FL Y P +RI+A   L H+YF   PLP  PS
Sbjct: 659 MTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPS 718

Query: 299 ELP 301
             P
Sbjct: 719 MFP 721


>gi|145309302 cell division cycle 2-like 5 isoform 1 [Homo sapiens]
          Length = 1512

 Score =  232 bits (591), Expect = 4e-61
 Identities = 121/313 (38%), Positives = 188/313 (60%), Gaps = 15/313 (4%)

Query: 1    MDQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGFPNQALREIKALQEMED 60
            +D++ I+G IGEG +G V+KA+  +TGE+VALKKV L   ++GFP  A+REIK L+++  
Sbjct: 702  VDKFDIIGIIGEGTYGQVYKARDKDTGEMVALKKVRLDNEKEGFPITAIREIKILRQLT- 760

Query: 61   NQYVVQLKAVFPHG----------GGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQM 110
            +Q ++ +K +              G F L FE+M  DL  ++        +  +KS+++ 
Sbjct: 761  HQSIINMKEIVTDKEDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFNENHIKSFMRQ 820

Query: 111  LLKGVAFCHANNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATRWYR 170
            L++G+ +CH  N +HRD+K +N+L++  GQ+K+ADFGLAR++S + SR YT++V T WYR
Sbjct: 821  LMEGLDYCHKKNFLHRDIKCSNILLNNRGQIKLADFGLARLYSSEESRPYTNKVITLWYR 880

Query: 171  APELLYGARQYDQGVDLWSVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQVWPE 230
             PELL G  +Y   +D+WS GCI+GEL    P+F    ++ QL  + RI G+P P VWP+
Sbjct: 881  PPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANQELAQLELISRICGSPCPAVWPD 940

Query: 231  LTELPDYNKISFKEQVPMPLEEVLPDVSPQALDLLGQFLLYPPHQRIAASKALLHQYFFT 290
            + +LP +N +  K+Q    L E    +   ALDL    L   P +R  A +AL  ++   
Sbjct: 941  VIKLPYFNTMKPKKQYRRKLREEFVFIPAAALDLFDYMLALDPSKRCTAEQALQCEFL-- 998

Query: 291  APLPAHPSELPIP 303
                  PS++P P
Sbjct: 999  --RDVEPSKMPPP 1009


>gi|145309300 cell division cycle 2-like 5 isoform 2 [Homo sapiens]
          Length = 1452

 Score =  232 bits (591), Expect = 4e-61
 Identities = 121/313 (38%), Positives = 188/313 (60%), Gaps = 15/313 (4%)

Query: 1    MDQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGFPNQALREIKALQEMED 60
            +D++ I+G IGEG +G V+KA+  +TGE+VALKKV L   ++GFP  A+REIK L+++  
Sbjct: 702  VDKFDIIGIIGEGTYGQVYKARDKDTGEMVALKKVRLDNEKEGFPITAIREIKILRQLT- 760

Query: 61   NQYVVQLKAVFPHG----------GGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQM 110
            +Q ++ +K +              G F L FE+M  DL  ++        +  +KS+++ 
Sbjct: 761  HQSIINMKEIVTDKEDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFNENHIKSFMRQ 820

Query: 111  LLKGVAFCHANNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATRWYR 170
            L++G+ +CH  N +HRD+K +N+L++  GQ+K+ADFGLAR++S + SR YT++V T WYR
Sbjct: 821  LMEGLDYCHKKNFLHRDIKCSNILLNNRGQIKLADFGLARLYSSEESRPYTNKVITLWYR 880

Query: 171  APELLYGARQYDQGVDLWSVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQVWPE 230
             PELL G  +Y   +D+WS GCI+GEL    P+F    ++ QL  + RI G+P P VWP+
Sbjct: 881  PPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANQELAQLELISRICGSPCPAVWPD 940

Query: 231  LTELPDYNKISFKEQVPMPLEEVLPDVSPQALDLLGQFLLYPPHQRIAASKALLHQYFFT 290
            + +LP +N +  K+Q    L E    +   ALDL    L   P +R  A +AL  ++   
Sbjct: 941  VIKLPYFNTMKPKKQYRRKLREEFVFIPAAALDLFDYMLALDPSKRCTAEQALQCEFL-- 998

Query: 291  APLPAHPSELPIP 303
                  PS++P P
Sbjct: 999  --RDVEPSKMPPP 1009


>gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2
            [Homo sapiens]
          Length = 1481

 Score =  231 bits (588), Expect = 9e-61
 Identities = 122/312 (39%), Positives = 188/312 (60%), Gaps = 12/312 (3%)

Query: 1    MDQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGFPNQALREIKALQEMED 60
            +D++ I+G IGEG +G V+KAK  +TGE+VALKKV L   ++GFP  A+REIK L+++  
Sbjct: 724  VDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQLI- 782

Query: 61   NQYVVQLKAVFPHG----------GGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQM 110
            ++ VV +K +              G F L FE+M  DL  ++       ++  +KS+++ 
Sbjct: 783  HRSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHIKSFMKQ 842

Query: 111  LLKGVAFCHANNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATRWYR 170
            L++G+ +CH  N +HRD+K +N+L++ SGQ+K+ADFGLAR+++ + SR YT++V T WYR
Sbjct: 843  LMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKVITLWYR 902

Query: 171  APELLYGARQYDQGVDLWSVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQVWPE 230
             PELL G  +Y   +D+WS GCI+GEL    P+F    ++ QL  + R+ G+P P VWP+
Sbjct: 903  PPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVWPD 962

Query: 231  LTELPDYNKISFKEQVPMPLEEVLPDVSPQALDLLGQFLLYPPHQRIAASKALLHQYFFT 290
            + +LP +N +  K+Q    L E    +   ALDLL   L   P +R  A + L   +   
Sbjct: 963  VIKLPYFNTMKPKKQYRRRLREEFSFIPSAALDLLDHMLTLDPSKRCTAEQTLQSDFLKD 1022

Query: 291  APL-PAHPSELP 301
              L    P +LP
Sbjct: 1023 VELSKMAPPDLP 1034


>gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1
            [Homo sapiens]
          Length = 1490

 Score =  231 bits (588), Expect = 9e-61
 Identities = 122/312 (39%), Positives = 188/312 (60%), Gaps = 12/312 (3%)

Query: 1    MDQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGFPNQALREIKALQEMED 60
            +D++ I+G IGEG +G V+KAK  +TGE+VALKKV L   ++GFP  A+REIK L+++  
Sbjct: 724  VDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQLI- 782

Query: 61   NQYVVQLKAVFPHG----------GGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQM 110
            ++ VV +K +              G F L FE+M  DL  ++       ++  +KS+++ 
Sbjct: 783  HRSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHIKSFMKQ 842

Query: 111  LLKGVAFCHANNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATRWYR 170
            L++G+ +CH  N +HRD+K +N+L++ SGQ+K+ADFGLAR+++ + SR YT++V T WYR
Sbjct: 843  LMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKVITLWYR 902

Query: 171  APELLYGARQYDQGVDLWSVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQVWPE 230
             PELL G  +Y   +D+WS GCI+GEL    P+F    ++ QL  + R+ G+P P VWP+
Sbjct: 903  PPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVWPD 962

Query: 231  LTELPDYNKISFKEQVPMPLEEVLPDVSPQALDLLGQFLLYPPHQRIAASKALLHQYFFT 290
            + +LP +N +  K+Q    L E    +   ALDLL   L   P +R  A + L   +   
Sbjct: 963  VIKLPYFNTMKPKKQYRRRLREEFSFIPSAALDLLDHMLTLDPSKRCTAEQTLQSDFLKD 1022

Query: 291  APL-PAHPSELP 301
              L    P +LP
Sbjct: 1023 VELSKMAPPDLP 1034


>gi|148596926 cyclin-dependent kinase 10 isoform a [Homo sapiens]
          Length = 360

 Score =  215 bits (547), Expect = 5e-56
 Identities = 118/297 (39%), Positives = 173/297 (58%), Gaps = 4/297 (1%)

Query: 7   LGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGFPNQALREIKALQEMEDNQYVVQ 66
           L RIGEG +GIV++A+  +T EIVALKKV + + +DG P  +LREI  L  +  +  +V+
Sbjct: 42  LNRIGEGTYGIVYRARDTQTDEIVALKKVRMDKEKDGIPISSLREITLLLRLR-HPNIVE 100

Query: 67  LKAVFP--HGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQMLLKGVAFCHANNIV 124
           LK V    H     L   +   DLA ++ +   P ++AQVK  +  +L+G+ + H N I+
Sbjct: 101 LKEVVVGNHLESIFLVMGYCEQDLASLLENMPTPFSEAQVKCIVLQVLRGLQYLHRNFII 160

Query: 125 HRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATRWYRAPELLYGARQYDQG 184
           HRDLK +NLL++  G +K ADFGLAR +      + T +V T WYRAPELL G       
Sbjct: 161 HRDLKVSNLLMTDKGCVKTADFGLARAYGVPVKPM-TPKVVTLWYRAPELLLGTTTQTTS 219

Query: 185 VDLWSVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQVWPELTELPDYNKISFKE 244
           +D+W+VGCI+ ELL   PL PG ++I Q+  ++++LGTP+  +WP  ++LP   + S ++
Sbjct: 220 IDMWAVGCILAELLAHRPLLPGTSEIHQIDLIVQLLGTPSENIWPGFSKLPLVGQYSLRK 279

Query: 245 QVPMPLEEVLPDVSPQALDLLGQFLLYPPHQRIAASKALLHQYFFTAPLPAHPSELP 301
           Q    L+   P +S   L LL    +Y P +R  A   L   YF   PLP  P  +P
Sbjct: 280 QPYNNLKHKFPWLSEAGLRLLHFLFMYDPKKRATAGDCLESSYFKEKPLPCEPELMP 336


>gi|47078233 PCTAIRE protein kinase 3 isoform a [Homo sapiens]
          Length = 504

 Score =  215 bits (547), Expect = 5e-56
 Identities = 111/288 (38%), Positives = 168/288 (58%), Gaps = 3/288 (1%)

Query: 1   MDQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGFPNQALREIKALQEMED 60
           ++ Y  L ++GEG +  VFK +   T  +VALK++ L   E+G P  A+RE+  L+ ++ 
Sbjct: 171 LETYVKLDKLGEGTYATVFKGRSKLTENLVALKEIRLEH-EEGAPCTAIREVSLLKNLK- 228

Query: 61  NQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQMLLKGVAFCHA 120
           +  +V L  +        L FE++ SDL + + H    ++   VK ++  LL+G+A+CH 
Sbjct: 229 HANIVTLHDLIHTDRSLTLVFEYLDSDLKQYLDHCGNLMSMHNVKIFMFQLLRGLAYCHH 288

Query: 121 NNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATRWYRAPELLYGARQ 180
             I+HRDLKP NLLI+  G+LK+ADFGLAR  S   ++ Y+++V T WYR P++L G+ +
Sbjct: 289 RKILHRDLKPQNLLINERGELKLADFGLARAKSVP-TKTYSNEVVTLWYRPPDVLLGSTE 347

Query: 181 YDQGVDLWSVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQVWPELTELPDYNKI 240
           Y   +D+W VGCI  E+  G PLFPG    E+L  + R+LGTP  + WP +T   ++   
Sbjct: 348 YSTPIDMWGVGCIHYEMATGRPLFPGSTVKEELHLIFRLLGTPTEETWPGVTAFSEFRTY 407

Query: 241 SFKEQVPMPLEEVLPDVSPQALDLLGQFLLYPPHQRIAASKALLHQYF 288
           SF   +P PL    P +    + LL   LLY    R++A  AL H YF
Sbjct: 408 SFPCYLPQPLINHAPRLDTDGIHLLSSLLLYESKSRMSAEAALSHSYF 455


>gi|47078231 PCTAIRE protein kinase 3 isoform b [Homo sapiens]
          Length = 474

 Score =  215 bits (547), Expect = 5e-56
 Identities = 111/288 (38%), Positives = 168/288 (58%), Gaps = 3/288 (1%)

Query: 1   MDQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGFPNQALREIKALQEMED 60
           ++ Y  L ++GEG +  VFK +   T  +VALK++ L   E+G P  A+RE+  L+ ++ 
Sbjct: 141 LETYVKLDKLGEGTYATVFKGRSKLTENLVALKEIRLEH-EEGAPCTAIREVSLLKNLK- 198

Query: 61  NQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQMLLKGVAFCHA 120
           +  +V L  +        L FE++ SDL + + H    ++   VK ++  LL+G+A+CH 
Sbjct: 199 HANIVTLHDLIHTDRSLTLVFEYLDSDLKQYLDHCGNLMSMHNVKIFMFQLLRGLAYCHH 258

Query: 121 NNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATRWYRAPELLYGARQ 180
             I+HRDLKP NLLI+  G+LK+ADFGLAR  S   ++ Y+++V T WYR P++L G+ +
Sbjct: 259 RKILHRDLKPQNLLINERGELKLADFGLARAKSVP-TKTYSNEVVTLWYRPPDVLLGSTE 317

Query: 181 YDQGVDLWSVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQVWPELTELPDYNKI 240
           Y   +D+W VGCI  E+  G PLFPG    E+L  + R+LGTP  + WP +T   ++   
Sbjct: 318 YSTPIDMWGVGCIHYEMATGRPLFPGSTVKEELHLIFRLLGTPTEETWPGVTAFSEFRTY 377

Query: 241 SFKEQVPMPLEEVLPDVSPQALDLLGQFLLYPPHQRIAASKALLHQYF 288
           SF   +P PL    P +    + LL   LLY    R++A  AL H YF
Sbjct: 378 SFPCYLPQPLINHAPRLDTDGIHLLSSLLLYESKSRMSAEAALSHSYF 425


>gi|47078229 PCTAIRE protein kinase 3 isoform b [Homo sapiens]
          Length = 474

 Score =  215 bits (547), Expect = 5e-56
 Identities = 111/288 (38%), Positives = 168/288 (58%), Gaps = 3/288 (1%)

Query: 1   MDQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGFPNQALREIKALQEMED 60
           ++ Y  L ++GEG +  VFK +   T  +VALK++ L   E+G P  A+RE+  L+ ++ 
Sbjct: 141 LETYVKLDKLGEGTYATVFKGRSKLTENLVALKEIRLEH-EEGAPCTAIREVSLLKNLK- 198

Query: 61  NQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQMLLKGVAFCHA 120
           +  +V L  +        L FE++ SDL + + H    ++   VK ++  LL+G+A+CH 
Sbjct: 199 HANIVTLHDLIHTDRSLTLVFEYLDSDLKQYLDHCGNLMSMHNVKIFMFQLLRGLAYCHH 258

Query: 121 NNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATRWYRAPELLYGARQ 180
             I+HRDLKP NLLI+  G+LK+ADFGLAR  S   ++ Y+++V T WYR P++L G+ +
Sbjct: 259 RKILHRDLKPQNLLINERGELKLADFGLARAKSVP-TKTYSNEVVTLWYRPPDVLLGSTE 317

Query: 181 YDQGVDLWSVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQVWPELTELPDYNKI 240
           Y   +D+W VGCI  E+  G PLFPG    E+L  + R+LGTP  + WP +T   ++   
Sbjct: 318 YSTPIDMWGVGCIHYEMATGRPLFPGSTVKEELHLIFRLLGTPTEETWPGVTAFSEFRTY 377

Query: 241 SFKEQVPMPLEEVLPDVSPQALDLLGQFLLYPPHQRIAASKALLHQYF 288
           SF   +P PL    P +    + LL   LLY    R++A  AL H YF
Sbjct: 378 SFPCYLPQPLINHAPRLDTDGIHLLSSLLLYESKSRMSAEAALSHSYF 425


>gi|4502747 cyclin-dependent kinase 9 [Homo sapiens]
          Length = 372

 Score =  214 bits (546), Expect = 7e-56
 Identities = 122/309 (39%), Positives = 177/309 (57%), Gaps = 16/309 (5%)

Query: 1   MDQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGFPNQALREIKALQEMED 60
           + +Y  L +IG+G  G VFKA+H +TG+ VALKKV +   ++GFP  ALREIK LQ ++ 
Sbjct: 16  VSKYEKLAKIGQGTFGEVFKARHRKTGQKVALKKVLMENEKEGFPITALREIKILQLLKH 75

Query: 61  NQYVVQLKA----VFPHG---GGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQMLLK 113
              V  ++       P+    G   L F+F   DLA ++ +       +++K  +QMLL 
Sbjct: 76  ENVVNLIEICRTKASPYNRCKGSIYLVFDFCEHDLAGLLSNVLVKFTLSEIKRVMQMLLN 135

Query: 114 GVAFCHANNIVHRDLKPANLLISASGQLKIADFGLARVFS---PDGSRLYTHQVATRWYR 170
           G+ + H N I+HRD+K AN+LI+  G LK+ADFGLAR FS         YT++V T WYR
Sbjct: 136 GLYYIHRNKILHRDMKAANVLITRDGVLKLADFGLARAFSLAKNSQPNRYTNRVVTLWYR 195

Query: 171 APELLYGARQYDQGVDLWSVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQVWPE 230
            PELL G R Y   +DLW  GCIM E+   SP+  G  +  QL  + ++ G+  P+VWP 
Sbjct: 196 PPELLLGERDYGPPIDLWGAGCIMAEMWTRSPIMQGNTEQHQLALISQLCGSITPEVWPN 255

Query: 231 LTELPDYNKISF----KEQVPMPLEEVLPDVSPQALDLLGQFLLYPPHQRIAASKALLHQ 286
           +     Y K+      K +V   L+  + D  P ALDL+ + L+  P QRI +  AL H 
Sbjct: 256 VDNYELYEKLELVKGQKRKVKDRLKAYVRD--PYALDLIDKLLVLDPAQRIDSDDALNHD 313

Query: 287 YFFTAPLPA 295
           +F++ P+P+
Sbjct: 314 FFWSDPMPS 322


>gi|37595545 PCTAIRE protein kinase 2 [Homo sapiens]
          Length = 523

 Score =  211 bits (538), Expect = 6e-55
 Identities = 103/288 (35%), Positives = 174/288 (60%), Gaps = 3/288 (1%)

Query: 1   MDQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGFPNQALREIKALQEMED 60
           M+ Y  L ++GEG +  V+K +   T  +VALK++ L   E+G P  A+RE+  L++++ 
Sbjct: 189 METYIKLEKLGEGTYATVYKGRSKLTENLVALKEIRLEH-EEGAPCTAIREVSLLKDLK- 246

Query: 61  NQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQMLLKGVAFCHA 120
           +  +V L  +        L FE++  DL + +      ++   VK +L  +L+G+A+CH 
Sbjct: 247 HANIVTLHDIVHTDKSLTLVFEYLDKDLKQYMDDCGNIMSMHNVKLFLYQILRGLAYCHR 306

Query: 121 NNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATRWYRAPELLYGARQ 180
             ++HRDLKP NLLI+  G+LK+ADFGLAR  S   ++ Y+++V T WYR P++L G+ +
Sbjct: 307 RKVLHRDLKPQNLLINEKGELKLADFGLARAKSVP-TKTYSNEVVTLWYRPPDVLLGSSE 365

Query: 181 YDQGVDLWSVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQVWPELTELPDYNKI 240
           Y   +D+W VGCI  E+ +G PLFPG    ++L  + R+LGTP+ + WP ++   ++   
Sbjct: 366 YSTQIDMWGVGCIFFEMASGRPLFPGSTVEDELHLIFRLLGTPSQETWPGISSNEEFKNY 425

Query: 241 SFKEQVPMPLEEVLPDVSPQALDLLGQFLLYPPHQRIAASKALLHQYF 288
           +F +  P PL    P +  + ++L+ +FL Y   +R++A +A+ H YF
Sbjct: 426 NFPKYKPQPLINHAPRLDSEGIELITKFLQYESKKRVSAEEAMKHVYF 473


>gi|83367069 cyclin-dependent kinase-like 5 [Homo sapiens]
          Length = 1030

 Score =  206 bits (525), Expect = 2e-53
 Identities = 118/295 (40%), Positives = 170/295 (57%), Gaps = 4/295 (1%)

Query: 1   MDQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGFPNQALREIKALQEMED 60
           M+++ ILG +GEGA+G+V K +H ET EIVA+KK       +      LRE+K L+ ++ 
Sbjct: 10  MNKFEILGVVGEGAYGVVLKCRHKETHEIVAIKKFKDSEENEEVKETTLRELKMLRTLKQ 69

Query: 61  NQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQMLLKGVAFCHA 120
              +V+LK  F   G   L FE++  ++ E++      +   +VKSY+  L+K + +CH 
Sbjct: 70  EN-IVELKEAFRRRGKLYLVFEYVEKNMLELLEEMPNGVPPEKVKSYIYQLIKAIHWCHK 128

Query: 121 NNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATRWYRAPELLYGARQ 180
           N+IVHRD+KP NLLIS +  LK+ DFG AR  S   +  YT  VATRWYR+PELL GA  
Sbjct: 129 NDIVHRDIKPENLLISHNDVLKLCDFGFARNLSEGNNANYTEYVATRWYRSPELLLGA-P 187

Query: 181 YDQGVDLWSVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQVWPELTELPDYNKI 240
           Y + VD+WSVGCI+GEL +G PLFPG+++I+QL  + ++LG    +        P ++ +
Sbjct: 188 YGKSVDMWSVGCILGELSDGQPLFPGESEIDQLFTIQKVLGPLPSEQMKLFYSNPRFHGL 247

Query: 241 SFKE-QVPMPLE-EVLPDVSPQALDLLGQFLLYPPHQRIAASKALLHQYFFTAPL 293
            F     P  LE   L  ++   LDL+   L   P  R    + L H  F T  L
Sbjct: 248 RFPAVNHPQSLERRYLGILNSVLLDLMKNLLKLDPADRYLTEQCLNHPTFQTQRL 302


>gi|4507281 cyclin-dependent kinase-like 5 [Homo sapiens]
          Length = 1030

 Score =  206 bits (525), Expect = 2e-53
 Identities = 118/295 (40%), Positives = 170/295 (57%), Gaps = 4/295 (1%)

Query: 1   MDQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGFPNQALREIKALQEMED 60
           M+++ ILG +GEGA+G+V K +H ET EIVA+KK       +      LRE+K L+ ++ 
Sbjct: 10  MNKFEILGVVGEGAYGVVLKCRHKETHEIVAIKKFKDSEENEEVKETTLRELKMLRTLKQ 69

Query: 61  NQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQMLLKGVAFCHA 120
              +V+LK  F   G   L FE++  ++ E++      +   +VKSY+  L+K + +CH 
Sbjct: 70  EN-IVELKEAFRRRGKLYLVFEYVEKNMLELLEEMPNGVPPEKVKSYIYQLIKAIHWCHK 128

Query: 121 NNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATRWYRAPELLYGARQ 180
           N+IVHRD+KP NLLIS +  LK+ DFG AR  S   +  YT  VATRWYR+PELL GA  
Sbjct: 129 NDIVHRDIKPENLLISHNDVLKLCDFGFARNLSEGNNANYTEYVATRWYRSPELLLGA-P 187

Query: 181 YDQGVDLWSVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQVWPELTELPDYNKI 240
           Y + VD+WSVGCI+GEL +G PLFPG+++I+QL  + ++LG    +        P ++ +
Sbjct: 188 YGKSVDMWSVGCILGELSDGQPLFPGESEIDQLFTIQKVLGPLPSEQMKLFYSNPRFHGL 247

Query: 241 SFKE-QVPMPLE-EVLPDVSPQALDLLGQFLLYPPHQRIAASKALLHQYFFTAPL 293
            F     P  LE   L  ++   LDL+   L   P  R    + L H  F T  L
Sbjct: 248 RFPAVNHPQSLERRYLGILNSVLLDLMKNLLKLDPADRYLTEQCLNHPTFQTQRL 302


>gi|197333744 PCTAIRE protein kinase 1 isoform 2 [Homo sapiens]
          Length = 502

 Score =  199 bits (506), Expect = 3e-51
 Identities = 104/290 (35%), Positives = 164/290 (56%), Gaps = 3/290 (1%)

Query: 1   MDQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGFPNQALREIKALQEMED 60
           ++ Y  L ++GEG +  V+K K   T  +VALK++ L   E+G P  A+RE+  L++++ 
Sbjct: 168 LETYIKLDKLGEGTYATVYKGKSKLTDNLVALKEIRLEH-EEGAPCTAIREVSLLKDLK- 225

Query: 61  NQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQMLLKGVAFCHA 120
           +  +V L  +        L FE++  DL + +      +    VK +L  LL+G+A+CH 
Sbjct: 226 HANIVTLHDIIHTEKSLTLVFEYLDKDLKQYLDDCGNIINMHNVKLFLFQLLRGLAYCHR 285

Query: 121 NNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATRWYRAPELLYGARQ 180
             ++HRDLKP NLLI+  G+LK+ADFGLAR  S   ++ Y+++V T WYR P++L G+  
Sbjct: 286 QKVLHRDLKPQNLLINERGELKLADFGLARAKSIP-TKTYSNEVVTLWYRPPDILLGSTD 344

Query: 181 YDQGVDLWSVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQVWPELTELPDYNKI 240
           Y   +D+W VGCI  E+  G PLFPG    EQL ++ RILGTP  + WP +    ++   
Sbjct: 345 YSTQIDMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFRILGTPTEETWPGILSNEEFKTY 404

Query: 241 SFKEQVPMPLEEVLPDVSPQALDLLGQFLLYPPHQRIAASKALLHQYFFT 290
           ++ +     L    P +     DLL + L +    RI+A  A+ H +F +
Sbjct: 405 NYPKYRAEALLSHAPRLDSDGADLLTKLLQFEGRNRISAEDAMKHPFFLS 454


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.141    0.434 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,043,465
Number of Sequences: 37866
Number of extensions: 811040
Number of successful extensions: 5174
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 740
Number of HSP's successfully gapped in prelim test: 82
Number of HSP's that attempted gapping in prelim test: 3102
Number of HSP's gapped (non-prelim): 1080
length of query: 346
length of database: 18,247,518
effective HSP length: 103
effective length of query: 243
effective length of database: 14,347,320
effective search space: 3486398760
effective search space used: 3486398760
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.