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Search of human proteins with 89274173
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|89274173 dynein heavy chain domain 2 isoform 2 [Homo
sapiens]
(457 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|89274173 dynein heavy chain domain 2 isoform 2 [Homo sapiens] 927 0.0
gi|194440727 dynein heavy chain domain 2 isoform 1 [Homo sapiens] 898 0.0
gi|151301127 dynein, axonemal, heavy chain 7 [Homo sapiens] 137 3e-32
gi|24308169 dynein, axonemal, heavy chain 3 [Homo sapiens] 85 1e-16
gi|239756957 PREDICTED: dynein, axonemal, heavy chain 17 [Homo s... 37 0.037
gi|239751459 PREDICTED: dynein, axonemal, heavy chain 17 [Homo s... 37 0.037
gi|239745966 PREDICTED: dynein, axonemal, heavy chain 17 [Homo s... 37 0.037
gi|48762726 phosphodiesterase 9A isoform f [Homo sapiens] 32 0.92
gi|48762718 phosphodiesterase 9A isoform b [Homo sapiens] 32 0.92
gi|194394168 centrosomal protein 27kDa isoform 2 [Homo sapiens] 32 1.6
gi|8922430 centrosomal protein 27kDa isoform 1 [Homo sapiens] 32 1.6
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H... 31 2.0
gi|237681119 breast cancer 1, early onset isoform 2 [Homo sapiens] 31 2.7
gi|237681121 breast cancer 1, early onset isoform 3 [Homo sapiens] 31 2.7
gi|6552299 breast cancer 1, early onset isoform 1 [Homo sapiens] 31 2.7
gi|71044479 death inducer-obliterator 1 isoform c [Homo sapiens] 31 2.7
gi|53729363 leucine rich repeat and sterile alpha motif containi... 30 3.5
gi|53729361 leucine rich repeat and sterile alpha motif containi... 30 3.5
gi|53729359 leucine rich repeat and sterile alpha motif containi... 30 3.5
gi|36031016 CTCL tumor antigen L14-2 [Homo sapiens] 30 3.5
gi|62899065 centrosomal protein 72 kDa [Homo sapiens] 30 3.5
gi|24429588 zinc finger protein 532 [Homo sapiens] 30 3.5
gi|170295804 estrogen receptor alpha isoform 4 [Homo sapiens] 30 4.6
gi|170295802 estrogen receptor alpha isoform 3 [Homo sapiens] 30 4.6
gi|170295800 estrogen receptor alpha isoform 2 [Homo sapiens] 30 4.6
gi|62821794 estrogen receptor alpha isoform 1 [Homo sapiens] 30 4.6
gi|242117953 SH3 domain-containing protein C1orf113 isoform 1 [H... 30 4.6
gi|242117948 SH3 domain-containing protein C1orf113 isoform 2 [H... 30 4.6
gi|224586823 coiled-coil domain containing 110 isoform b [Homo s... 30 4.6
gi|22749515 coiled-coil domain containing 110 isoform a [Homo sa... 30 4.6
>gi|89274173 dynein heavy chain domain 2 isoform 2 [Homo sapiens]
Length = 457
Score = 927 bits (2395), Expect = 0.0
Identities = 457/457 (100%), Positives = 457/457 (100%)
Query: 1 MSDANKAAIAAEKEALNLKLPPIVHLPENIGVDTPTQSKLLKYRRSKEQQQKINQLVIDG 60
MSDANKAAIAAEKEALNLKLPPIVHLPENIGVDTPTQSKLLKYRRSKEQQQKINQLVIDG
Sbjct: 1 MSDANKAAIAAEKEALNLKLPPIVHLPENIGVDTPTQSKLLKYRRSKEQQQKINQLVIDG 60
Query: 61 AKRNLDRTLGKRTPLLPPPDYPQTMTSEMKKKGFNYIYMKQCVESSPLVPIQQEWLDHML 120
AKRNLDRTLGKRTPLLPPPDYPQTMTSEMKKKGFNYIYMKQCVESSPLVPIQQEWLDHML
Sbjct: 61 AKRNLDRTLGKRTPLLPPPDYPQTMTSEMKKKGFNYIYMKQCVESSPLVPIQQEWLDHML 120
Query: 121 RLIPESLKEGKEREELLESLINEVSSDFENSMKRYLVQSVLVKPPVKSLEDEGGPLPESP 180
RLIPESLKEGKEREELLESLINEVSSDFENSMKRYLVQSVLVKPPVKSLEDEGGPLPESP
Sbjct: 121 RLIPESLKEGKEREELLESLINEVSSDFENSMKRYLVQSVLVKPPVKSLEDEGGPLPESP 180
Query: 181 VGLDYSNPWHSSYVQARNQIFSNLHIIHPTMKMLLDLGYTTFADTVLLDFTGIRAKGPID 240
VGLDYSNPWHSSYVQARNQIFSNLHIIHPTMKMLLDLGYTTFADTVLLDFTGIRAKGPID
Sbjct: 181 VGLDYSNPWHSSYVQARNQIFSNLHIIHPTMKMLLDLGYTTFADTVLLDFTGIRAKGPID 240
Query: 241 CESLKTDLSIQTRNAEEKIMNTWYPKVINLFTKKEALEGVKPEKLDAFYSCVSTLMSNQL 300
CESLKTDLSIQTRNAEEKIMNTWYPKVINLFTKKEALEGVKPEKLDAFYSCVSTLMSNQL
Sbjct: 241 CESLKTDLSIQTRNAEEKIMNTWYPKVINLFTKKEALEGVKPEKLDAFYSCVSTLMSNQL 300
Query: 301 KDLLRRTVEGFVKLFDPKDQQRLPIFKIELTFDDDKMEFYPTFQDLEDNVLSLVERIAEA 360
KDLLRRTVEGFVKLFDPKDQQRLPIFKIELTFDDDKMEFYPTFQDLEDNVLSLVERIAEA
Sbjct: 301 KDLLRRTVEGFVKLFDPKDQQRLPIFKIELTFDDDKMEFYPTFQDLEDNVLSLVERIAEA 360
Query: 361 LQNVQTIPSWLSGTSTPVNLDTELPEHVLHWAVDTLKAAVHRNLEGARKHYETYVEKYNW 420
LQNVQTIPSWLSGTSTPVNLDTELPEHVLHWAVDTLKAAVHRNLEGARKHYETYVEKYNW
Sbjct: 361 LQNVQTIPSWLSGTSTPVNLDTELPEHVLHWAVDTLKAAVHRNLEGARKHYETYVEKYNW 420
Query: 421 LLDGTAVENIETFQTEDHTFDEYTEELDCWVVWEVYF 457
LLDGTAVENIETFQTEDHTFDEYTEELDCWVVWEVYF
Sbjct: 421 LLDGTAVENIETFQTEDHTFDEYTEELDCWVVWEVYF 457
>gi|194440727 dynein heavy chain domain 2 isoform 1 [Homo sapiens]
Length = 3092
Score = 898 bits (2320), Expect = 0.0
Identities = 445/448 (99%), Positives = 447/448 (99%)
Query: 1 MSDANKAAIAAEKEALNLKLPPIVHLPENIGVDTPTQSKLLKYRRSKEQQQKINQLVIDG 60
MSDANKAAIAAEKEALNLKLPPIVHLPENIGVDTPTQSKLLKYRRSKEQQQKINQLVIDG
Sbjct: 1 MSDANKAAIAAEKEALNLKLPPIVHLPENIGVDTPTQSKLLKYRRSKEQQQKINQLVIDG 60
Query: 61 AKRNLDRTLGKRTPLLPPPDYPQTMTSEMKKKGFNYIYMKQCVESSPLVPIQQEWLDHML 120
AKRNLDRTLGKRTPLLPPPDYPQTMTSEMKKKGFNYIYMKQCVESSPLVPIQQEWLDHML
Sbjct: 61 AKRNLDRTLGKRTPLLPPPDYPQTMTSEMKKKGFNYIYMKQCVESSPLVPIQQEWLDHML 120
Query: 121 RLIPESLKEGKEREELLESLINEVSSDFENSMKRYLVQSVLVKPPVKSLEDEGGPLPESP 180
RLIPESLKEGKEREELLESLINEVSSDFENSMKRYLVQSVLVKPPVKSLEDEGGPLPESP
Sbjct: 121 RLIPESLKEGKEREELLESLINEVSSDFENSMKRYLVQSVLVKPPVKSLEDEGGPLPESP 180
Query: 181 VGLDYSNPWHSSYVQARNQIFSNLHIIHPTMKMLLDLGYTTFADTVLLDFTGIRAKGPID 240
VGLDYSNPWHSSYVQARNQIFSNLHIIHPTMKMLLDLGYTTFADTVLLDFTGIRAKGPID
Sbjct: 181 VGLDYSNPWHSSYVQARNQIFSNLHIIHPTMKMLLDLGYTTFADTVLLDFTGIRAKGPID 240
Query: 241 CESLKTDLSIQTRNAEEKIMNTWYPKVINLFTKKEALEGVKPEKLDAFYSCVSTLMSNQL 300
CESLKTDLSIQTRNAEEKIMNTWYPKVINLFTKKEALEGVKPEKLDAFYSCVSTLMSNQL
Sbjct: 241 CESLKTDLSIQTRNAEEKIMNTWYPKVINLFTKKEALEGVKPEKLDAFYSCVSTLMSNQL 300
Query: 301 KDLLRRTVEGFVKLFDPKDQQRLPIFKIELTFDDDKMEFYPTFQDLEDNVLSLVERIAEA 360
KDLLRRTVEGFVKLFDPKDQQRLPIFKIELTFDDDKMEFYPTFQDLEDNVLSLVERIAEA
Sbjct: 301 KDLLRRTVEGFVKLFDPKDQQRLPIFKIELTFDDDKMEFYPTFQDLEDNVLSLVERIAEA 360
Query: 361 LQNVQTIPSWLSGTSTPVNLDTELPEHVLHWAVDTLKAAVHRNLEGARKHYETYVEKYNW 420
LQNVQTIPSWLSGTSTPVNLDTELPEHVLHWAVDTLKAAVHRNLEGARKHYETYVEKYNW
Sbjct: 361 LQNVQTIPSWLSGTSTPVNLDTELPEHVLHWAVDTLKAAVHRNLEGARKHYETYVEKYNW 420
Query: 421 LLDGTAVENIETFQTEDHTFDEYTEELD 448
LLDGTAVENIETFQTEDHTFDEYTE ++
Sbjct: 421 LLDGTAVENIETFQTEDHTFDEYTEFIE 448
>gi|151301127 dynein, axonemal, heavy chain 7 [Homo sapiens]
Length = 4024
Score = 137 bits (344), Expect = 3e-32
Identities = 92/366 (25%), Positives = 184/366 (50%), Gaps = 18/366 (4%)
Query: 96 YIYMKQCVESSPLVPIQQEWLDHMLRLIPESLKEGKEREELLESLINEVSSDFENSMKRY 155
Y Y+ +++ + P++ WL+H+L L+P+ LK + + +L +E+ D+ S+++
Sbjct: 165 YYYIHHGIDTDHVAPMEDSWLEHVLDLVPQHLKVFTDS---IVTLSDEMREDYLLSVRKS 221
Query: 156 LVQSVLVKPPVKSLEDEGGPLPESPVGLDY-SNPWHSSYVQARNQIFSNLHIIHPTMKML 214
+V VL P K + + LP ++ PW S++ A + I +L+ ++PTM +
Sbjct: 222 IVDFVLKDPREKGDDKKTDELPAHRAEMEILPKPWRKSFLAASSYIRDHLNAMNPTMLAV 281
Query: 215 LDLGYTTFADTVLLDFTGI-RAKGPIDCESLKTDLSIQTRNAEEKIMNTWYPKVINLF-- 271
LDL +T F L+D + ++ S + + +A+E ++ W+P+V N++
Sbjct: 282 LDLWHTNFKKLRLVDIKEFHNCQDALELSSFQNIIMRHMDSAKETLLKMWFPEVQNIYYQ 341
Query: 272 --TKKEALEGVKPEKLDAFYSCVSTLMSNQLKDLLRRTVEGFVKLF-DPKDQQRL---PI 325
KK+ G KL++F++C + LM+ QL+DL +++ F L P D R P
Sbjct: 342 GNKKKQLPTGDSSAKLESFFNCAAALMTLQLQDLTLVSMQDFTDLIAQPPDSVRAFEHPG 401
Query: 326 FKIELTFDDDKMEFYPTFQDLEDNVLSLVERIAEALQNVQTIPSWLSGTSTPVNLDTELP 385
F + L D+D ++F P D D L++ + + +A+ V + + L + T L
Sbjct: 402 FIMRLILDNDTIKFEPELSDYIDIFLNVYDVMIKAVSFVPRVETKLYSKWESKSKPTTLK 461
Query: 386 EHVLHWAVDT----LKAAVHRNLEGARKHYETYVEKYNWLLDGTAVENIETFQTEDHTFD 441
+L+ VD +K + + +H Y +KY++L+ A +++ F E+H+++
Sbjct: 462 PIILNEIVDAHKEKIKEVIMKESVAPTEHLRLY-DKYDFLITRKAERDVDNFLAENHSYE 520
Query: 442 EYTEEL 447
+ +E+
Sbjct: 521 KIIDEI 526
>gi|24308169 dynein, axonemal, heavy chain 3 [Homo sapiens]
Length = 4116
Score = 85.1 bits (209), Expect = 1e-16
Identities = 91/414 (21%), Positives = 171/414 (41%), Gaps = 66/414 (15%)
Query: 96 YIYMKQCVESSPLVPIQQEWLDHMLRLIPESLKEGKEREELLESLINEVSSDFENSMKRY 155
Y Y+ + + P + E + + +LI +L E L+ L+ E +D+ S+ +
Sbjct: 235 YYYLTNGIRKDMIAPEEGEVMVRISKLISNTLLTSPFLEPLMVVLVQEKENDYYCSLMKS 294
Query: 156 LVQSVLVKPPVKS---LEDEGGPLPESPVGLDYSNPWHSSYVQARNQIFSNLHIIHPTMK 212
+V +L+ P + +E P+ + PWHS Y A+ +LH ++P M
Sbjct: 295 IVDYILMDPMERKRLFIESIPRLFPQRVIRAPV--PWHSVYRSAKKWNEEHLHTVNPMML 352
Query: 213 MLLDLGYTTFADTVLLDFTGIRA-KGPIDCESLKTDLSIQTRNAEEKIMNTWYPKVINLF 271
L +L + F D + I A K P+ + + A + ++N W P LF
Sbjct: 353 RLKELWFAEFRDLRFVRTAEILAGKLPLQPQEFWDVIQKHCLEAHQTLLNKWIPTCAQLF 412
Query: 272 T-KKEALEGVKPE-------KLDAFYSCVSTLMSNQLKDLLRRTVEGFVKLF-------- 315
T +KE P+ ++ +++ V++ MS QL++L+ +++E V LF
Sbjct: 413 TSRKEHWIHFAPKSNYDSSRNIEEYFASVASFMSLQLRELVIKSLEDLVSLFMIHKDGND 472
Query: 316 --DPKDQQRL---PIFKIELTFDDDKMEFYPTFQD----LEDNVLSLVERIAEALQNVQT 366
+P + + + I+L + + F P+F + D+ L +++ + + ++
Sbjct: 473 FKEPYQEMKFFIPQLIMIKLEVSEPIIVFNPSFDGCWELIRDSFLEIIKN-SNGIPKLKY 531
Query: 367 IPSWLSGTSTPVNLD----TELPEHVLHWA----------------------------VD 394
IP S T+ + E E +H A +
Sbjct: 532 IPLKFSFTAAAADRQCVKAAEPGEPSMHAAATAMAELKGYNLLLGTVNAEEKLVSDFLIQ 591
Query: 395 TLKAAVHRNLEGARKHYETYVEKYNWLLDGTAVENIETFQTEDHTFDEYTEELD 448
T K +N G K+ Y +KY LLD TA +NI F E+H D++ +++
Sbjct: 592 TFK-VFQKNQVGPCKYLNVY-KKYVDLLDNTAEQNIAAFLKENHDIDDFVTKIN 643
>gi|239756957 PREDICTED: dynein, axonemal, heavy chain 17 [Homo
sapiens]
Length = 4470
Score = 37.0 bits (84), Expect = 0.037
Identities = 29/133 (21%), Positives = 57/133 (42%), Gaps = 5/133 (3%)
Query: 319 DQQRLPIFKIELTFDDDKMEFYPTFQDLED-NVLSLVERIAEALQNVQTIPSWLSGTSTP 377
D+ P+F+I + D+D + F PT + D L+L+E + + NV + L+
Sbjct: 901 DESIAPLFEIRMELDEDGLTFNPTLEVGSDRGFLALIEGLVNDIYNVARLIPRLAKDRMN 960
Query: 378 VNLDTELPEHVLHWAVDTLKAAVHRNLEGARKHYETYVEKYNWLLDGTAVENIETFQTED 437
+D E ++ + ++ E + Y+ E+Y++L E ++ F
Sbjct: 961 YKMDLEDNTDLIEMREEVSSLVINAMKEA--EEYQDSFERYSYLWTDNLQEFMKNFLI-- 1016
Query: 438 HTFDEYTEELDCW 450
+ E+LD W
Sbjct: 1017 YGCAVTAEDLDTW 1029
>gi|239751459 PREDICTED: dynein, axonemal, heavy chain 17 [Homo
sapiens]
Length = 4485
Score = 37.0 bits (84), Expect = 0.037
Identities = 29/133 (21%), Positives = 57/133 (42%), Gaps = 5/133 (3%)
Query: 319 DQQRLPIFKIELTFDDDKMEFYPTFQDLED-NVLSLVERIAEALQNVQTIPSWLSGTSTP 377
D+ P+F+I + D+D + F PT + D L+L+E + + NV + L+
Sbjct: 892 DESIAPLFEIRMELDEDGLTFNPTLEVGSDRGFLALIEGLVNDIYNVARLIPRLAKDRMN 951
Query: 378 VNLDTELPEHVLHWAVDTLKAAVHRNLEGARKHYETYVEKYNWLLDGTAVENIETFQTED 437
+D E ++ + ++ E + Y+ E+Y++L E ++ F
Sbjct: 952 YKMDLEDNTDLIEMREEVSSLVINAMKEA--EEYQDSFERYSYLWTDNLQEFMKNFLI-- 1007
Query: 438 HTFDEYTEELDCW 450
+ E+LD W
Sbjct: 1008 YGCAVTAEDLDTW 1020
>gi|239745966 PREDICTED: dynein, axonemal, heavy chain 17 [Homo
sapiens]
Length = 4485
Score = 37.0 bits (84), Expect = 0.037
Identities = 29/133 (21%), Positives = 57/133 (42%), Gaps = 5/133 (3%)
Query: 319 DQQRLPIFKIELTFDDDKMEFYPTFQDLED-NVLSLVERIAEALQNVQTIPSWLSGTSTP 377
D+ P+F+I + D+D + F PT + D L+L+E + + NV + L+
Sbjct: 892 DESIAPLFEIRMELDEDGLTFNPTLEVGSDRGFLALIEGLVNDIYNVARLIPRLAKDRMN 951
Query: 378 VNLDTELPEHVLHWAVDTLKAAVHRNLEGARKHYETYVEKYNWLLDGTAVENIETFQTED 437
+D E ++ + ++ E + Y+ E+Y++L E ++ F
Sbjct: 952 YKMDLEDNTDLIEMREEVSSLVINAMKEA--EEYQDSFERYSYLWTDNLQEFMKNFLI-- 1007
Query: 438 HTFDEYTEELDCW 450
+ E+LD W
Sbjct: 1008 YGCAVTAEDLDTW 1020
>gi|48762726 phosphodiesterase 9A isoform f [Homo sapiens]
Length = 492
Score = 32.3 bits (72), Expect = 0.92
Identities = 16/51 (31%), Positives = 29/51 (56%), Gaps = 2/51 (3%)
Query: 103 VESSPLVPIQQEWLDHMLRLIPESLKEGKEREELLESLINEVSSDFENSMK 153
V P +P E + +R P ++K+ EREEL++S++ +V+ F + K
Sbjct: 20 VSIDPTMPANSERTPYKVR--PVAIKQLSEREELIQSVLAQVAEQFSRAFK 68
>gi|48762718 phosphodiesterase 9A isoform b [Homo sapiens]
Length = 533
Score = 32.3 bits (72), Expect = 0.92
Identities = 16/51 (31%), Positives = 29/51 (56%), Gaps = 2/51 (3%)
Query: 103 VESSPLVPIQQEWLDHMLRLIPESLKEGKEREELLESLINEVSSDFENSMK 153
V P +P E + +R P ++K+ EREEL++S++ +V+ F + K
Sbjct: 61 VSIDPTMPANSERTPYKVR--PVAIKQLSEREELIQSVLAQVAEQFSRAFK 109
>gi|194394168 centrosomal protein 27kDa isoform 2 [Homo sapiens]
Length = 204
Score = 31.6 bits (70), Expect = 1.6
Identities = 23/96 (23%), Positives = 41/96 (42%)
Query: 296 MSNQLKDLLRRTVEGFVKLFDPKDQQRLPIFKIELTFDDDKMEFYPTFQDLEDNVLSLVE 355
M+N L+ +L+ +L P Q+ LPI + + +E TF + + L +
Sbjct: 64 MNNHLEAVLKEKRSLRQRLLKPMCQENLPIEAVYHRYMVHLLELAVTFIERLETHLETIR 123
Query: 356 RIAEALQNVQTIPSWLSGTSTPVNLDTELPEHVLHW 391
I N++ + L+ V EL E++L W
Sbjct: 124 NIPHLAANLKKMNQALAKMDILVTETEELAENILKW 159
>gi|8922430 centrosomal protein 27kDa isoform 1 [Homo sapiens]
Length = 235
Score = 31.6 bits (70), Expect = 1.6
Identities = 23/96 (23%), Positives = 41/96 (42%)
Query: 296 MSNQLKDLLRRTVEGFVKLFDPKDQQRLPIFKIELTFDDDKMEFYPTFQDLEDNVLSLVE 355
M+N L+ +L+ +L P Q+ LPI + + +E TF + + L +
Sbjct: 95 MNNHLEAVLKEKRSLRQRLLKPMCQENLPIEAVYHRYMVHLLELAVTFIERLETHLETIR 154
Query: 356 RIAEALQNVQTIPSWLSGTSTPVNLDTELPEHVLHW 391
I N++ + L+ V EL E++L W
Sbjct: 155 NIPHLAANLKKMNQALAKMDILVTETEELAENILKW 190
>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
sapiens]
Length = 1940
Score = 31.2 bits (69), Expect = 2.0
Identities = 36/159 (22%), Positives = 68/159 (42%), Gaps = 8/159 (5%)
Query: 3 DANKAAIAAEKEALN----LKLPPIVHLPENIGVDTPTQSKL---LKYRRSKEQQQKINQ 55
D A + EK+AL L + + + T+SKL ++ S +Q+K +
Sbjct: 987 DETIAKLTREKKALQEAHQQALDDLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQEKKLR 1046
Query: 56 LVIDGAKRNLDRTLG-KRTPLLPPPDYPQTMTSEMKKKGFNYIYMKQCVESSPLVPIQQE 114
+ ++ KR L+ L + +L + Q + +KKK F Y ++ VE + +Q +
Sbjct: 1047 VDLERNKRKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQ 1106
Query: 115 WLDHMLRLIPESLKEGKEREELLESLINEVSSDFENSMK 153
L+ E L+E E E + + SD+ ++
Sbjct: 1107 KKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELE 1145
>gi|237681119 breast cancer 1, early onset isoform 2 [Homo sapiens]
Length = 1884
Score = 30.8 bits (68), Expect = 2.7
Identities = 37/176 (21%), Positives = 66/176 (37%), Gaps = 29/176 (16%)
Query: 117 DHMLRLIPESLKEGKEREELLESLINEVSSDFENSMKRYLVQSVLVKPPVKSLEDEGG-- 174
D ++ PE + +G + E ++N +S EN K +Q+ P++SLE E
Sbjct: 522 DLAVQKTPEMINQGTNQTEQNGQVMNITNSGHENKTKGDSIQNEKNPNPIESLEKESAFK 581
Query: 175 ----PLPESPVGLDYSNPWHSSYVQARNQI--FSNLHIIHPTMKMLLDLGYTTFADTVLL 228
P+ S ++ H+S +N++ S+ IH L
Sbjct: 582 TKAEPISSSISNMELELNIHNSKAPKKNRLRRKSSTRHIH------------------AL 623
Query: 229 DFTGIRAKGPIDCESLKTDLSIQTRNAEEKIMNTW---YPKVINLFTKKEALEGVK 281
+ R P +C L+ D + ++K N + + + L KE G K
Sbjct: 624 ELVVSRNLSPPNCTELQIDSCSSSEEIKKKKYNQMPVRHSRNLQLMEGKEPATGAK 679
>gi|237681121 breast cancer 1, early onset isoform 3 [Homo sapiens]
Length = 1816
Score = 30.8 bits (68), Expect = 2.7
Identities = 37/176 (21%), Positives = 66/176 (37%), Gaps = 29/176 (16%)
Query: 117 DHMLRLIPESLKEGKEREELLESLINEVSSDFENSMKRYLVQSVLVKPPVKSLEDEGG-- 174
D ++ PE + +G + E ++N +S EN K +Q+ P++SLE E
Sbjct: 475 DLAVQKTPEMINQGTNQTEQNGQVMNITNSGHENKTKGDSIQNEKNPNPIESLEKESAFK 534
Query: 175 ----PLPESPVGLDYSNPWHSSYVQARNQI--FSNLHIIHPTMKMLLDLGYTTFADTVLL 228
P+ S ++ H+S +N++ S+ IH L
Sbjct: 535 TKAEPISSSISNMELELNIHNSKAPKKNRLRRKSSTRHIH------------------AL 576
Query: 229 DFTGIRAKGPIDCESLKTDLSIQTRNAEEKIMNTW---YPKVINLFTKKEALEGVK 281
+ R P +C L+ D + ++K N + + + L KE G K
Sbjct: 577 ELVVSRNLSPPNCTELQIDSCSSSEEIKKKKYNQMPVRHSRNLQLMEGKEPATGAK 632
>gi|6552299 breast cancer 1, early onset isoform 1 [Homo sapiens]
Length = 1863
Score = 30.8 bits (68), Expect = 2.7
Identities = 37/176 (21%), Positives = 66/176 (37%), Gaps = 29/176 (16%)
Query: 117 DHMLRLIPESLKEGKEREELLESLINEVSSDFENSMKRYLVQSVLVKPPVKSLEDEGG-- 174
D ++ PE + +G + E ++N +S EN K +Q+ P++SLE E
Sbjct: 522 DLAVQKTPEMINQGTNQTEQNGQVMNITNSGHENKTKGDSIQNEKNPNPIESLEKESAFK 581
Query: 175 ----PLPESPVGLDYSNPWHSSYVQARNQI--FSNLHIIHPTMKMLLDLGYTTFADTVLL 228
P+ S ++ H+S +N++ S+ IH L
Sbjct: 582 TKAEPISSSISNMELELNIHNSKAPKKNRLRRKSSTRHIH------------------AL 623
Query: 229 DFTGIRAKGPIDCESLKTDLSIQTRNAEEKIMNTW---YPKVINLFTKKEALEGVK 281
+ R P +C L+ D + ++K N + + + L KE G K
Sbjct: 624 ELVVSRNLSPPNCTELQIDSCSSSEEIKKKKYNQMPVRHSRNLQLMEGKEPATGAK 679
>gi|71044479 death inducer-obliterator 1 isoform c [Homo sapiens]
Length = 2240
Score = 30.8 bits (68), Expect = 2.7
Identities = 22/89 (24%), Positives = 40/89 (44%), Gaps = 4/89 (4%)
Query: 80 DYPQTMTSEMKKKGFNYIYMKQCVESSPLVPIQQEWLDHMLRLIPESLKEGKEREELLES 139
D P M +++++ ++P + QQ+ L+ + + I E ++ +E+EE L
Sbjct: 1443 DLPNRMCADVRRNSVERPAEPVAGAATPSLVEQQKMLEELNKQIEEQKRQLEEQEEALRQ 1502
Query: 140 LINEVSSDFENSMKRYLVQSVLVKPPVKS 168
V SM + V L+ PP KS
Sbjct: 1503 QRAAVGV----SMAHFSVSDALMSPPPKS 1527
>gi|53729363 leucine rich repeat and sterile alpha motif containing
1 [Homo sapiens]
Length = 723
Score = 30.4 bits (67), Expect = 3.5
Identities = 22/90 (24%), Positives = 46/90 (51%), Gaps = 13/90 (14%)
Query: 88 EMKKKGFNYIYMKQCVESSPLVPIQQEWLDHMLRLIPESLKEGKEREELLESLINEVSSD 147
E+K+K + +++ + +Q W + L+ + LKE ++REE L ++ E+ +
Sbjct: 489 ELKRKSLDTESLQEMIS-------EQRWA--LSSLLQQLLKEKQQREEELREILTELEAK 539
Query: 148 FENSMKRYLV---QSVLVKPPVK-SLEDEG 173
E + Y + Q +L + P+ L++EG
Sbjct: 540 SETRQENYWLIQYQRLLNQKPLSLKLQEEG 569
>gi|53729361 leucine rich repeat and sterile alpha motif containing
1 [Homo sapiens]
Length = 723
Score = 30.4 bits (67), Expect = 3.5
Identities = 22/90 (24%), Positives = 46/90 (51%), Gaps = 13/90 (14%)
Query: 88 EMKKKGFNYIYMKQCVESSPLVPIQQEWLDHMLRLIPESLKEGKEREELLESLINEVSSD 147
E+K+K + +++ + +Q W + L+ + LKE ++REE L ++ E+ +
Sbjct: 489 ELKRKSLDTESLQEMIS-------EQRWA--LSSLLQQLLKEKQQREEELREILTELEAK 539
Query: 148 FENSMKRYLV---QSVLVKPPVK-SLEDEG 173
E + Y + Q +L + P+ L++EG
Sbjct: 540 SETRQENYWLIQYQRLLNQKPLSLKLQEEG 569
>gi|53729359 leucine rich repeat and sterile alpha motif containing
1 [Homo sapiens]
Length = 723
Score = 30.4 bits (67), Expect = 3.5
Identities = 22/90 (24%), Positives = 46/90 (51%), Gaps = 13/90 (14%)
Query: 88 EMKKKGFNYIYMKQCVESSPLVPIQQEWLDHMLRLIPESLKEGKEREELLESLINEVSSD 147
E+K+K + +++ + +Q W + L+ + LKE ++REE L ++ E+ +
Sbjct: 489 ELKRKSLDTESLQEMIS-------EQRWA--LSSLLQQLLKEKQQREEELREILTELEAK 539
Query: 148 FENSMKRYLV---QSVLVKPPVK-SLEDEG 173
E + Y + Q +L + P+ L++EG
Sbjct: 540 SETRQENYWLIQYQRLLNQKPLSLKLQEEG 569
>gi|36031016 CTCL tumor antigen L14-2 [Homo sapiens]
Length = 898
Score = 30.4 bits (67), Expect = 3.5
Identities = 35/130 (26%), Positives = 56/130 (43%), Gaps = 16/130 (12%)
Query: 39 KLLKYRRSKEQQQKINQLVIDGAK----RNLDRTLGK--------RTPLLPPPDYPQTMT 86
++ K K+ Q+K +QL + AK +L RT + RT + D
Sbjct: 457 RVTKGELEKQMQEKSDQLEMHHAKIKELEDLKRTFKEGMDELRTLRTKVKCLEDERLRTE 516
Query: 87 SEMKKKGFNYIYMKQCVESSPLVPIQQ--EWLDHMLRLIPESLKEGKEREELLESLINEV 144
E+ K + I +Q E L+ + + L L+ + ++ KE E L SLIN++
Sbjct: 517 DELSK--YKEIINRQKAEIQNLLDKVKTADQLQEQLQRGKQEIENLKEEVESLNSLINDL 574
Query: 145 SSDFENSMKR 154
D E S KR
Sbjct: 575 QKDIEGSRKR 584
>gi|62899065 centrosomal protein 72 kDa [Homo sapiens]
Length = 647
Score = 30.4 bits (67), Expect = 3.5
Identities = 31/116 (26%), Positives = 53/116 (45%), Gaps = 13/116 (11%)
Query: 276 ALEGVKP----EKLDAFYSCVSTLMSNQLKDLLRRTVEGFVKLFDPKDQQRLPIFKIELT 331
+LEG++ E L+ +Y+C+S+L ++ R + +L D D + P+ K+E
Sbjct: 68 SLEGIQYLTALESLNLYYNCISSLA-----EVFR--LHALTELVDV-DFRLNPVVKVEPD 119
Query: 332 FDDDKMEFYPTFQDLEDNVLSLVERIAEALQNVQTIPSWLSGTSTPVNLDTELPEH 387
+ + P Q L+D + ER A L + + S S S P +L P H
Sbjct: 120 YRLFVVHLLPKLQQLDDRPVRASERKASRL-HFASEDSLDSKESVPASLKEGRPHH 174
>gi|24429588 zinc finger protein 532 [Homo sapiens]
Length = 1301
Score = 30.4 bits (67), Expect = 3.5
Identities = 42/174 (24%), Positives = 75/174 (43%), Gaps = 33/174 (18%)
Query: 7 AAIAAEKEALNLKLPPIVHLPENIGVDTPTQSKLLKYRRSKEQQQKINQLVIDGAKRNLD 66
AA++A+K A + P+ + E+ +P ++ R+ ++ + +Q +IDG K+
Sbjct: 275 AALSAKKAASDSCKEPVANSRES----SPLPKEVNDSPRAADKSPE-SQNLIDGTKK--- 326
Query: 67 RTLGKRTPLLPPPDYPQTMTSEMKKKGFNYIYMKQCVESSPLVP---------IQQEWLD 117
P L PD P++++SE KG S+P +P E
Sbjct: 327 -------PSLKQPDSPRSISSENSSKG----SPSSPAGSTPAIPKVRIKTIKTSSGEIKR 375
Query: 118 HMLRLIPE-SLKEGKEREELLESLINEVSSDFENSMKRYLVQSVLVKPPVKSLE 170
+ R++PE L GK+ E S++ V+S + +VL PP L+
Sbjct: 376 TVTRVLPEVDLDSGKKPSEQTASVMASVTSLLSSPAS----AAVLSSPPRAPLQ 425
>gi|170295804 estrogen receptor alpha isoform 4 [Homo sapiens]
Length = 595
Score = 30.0 bits (66), Expect = 4.6
Identities = 19/69 (27%), Positives = 32/69 (46%), Gaps = 1/69 (1%)
Query: 89 MKKKGFNYIYMKQCVESSPLVPIQQEWLDHMLRLIPESLKEGKEREELLESLINEVSSDF 148
M KG ++Y +C PL + E LD RL + + G EE +S + S
Sbjct: 517 MSNKGMEHLYSMKCKNVVPLYDLLLEMLD-AHRLHAPTSRGGASVEETDQSHLATAGSTS 575
Query: 149 ENSMKRYLV 157
+S+++Y +
Sbjct: 576 SHSLQKYYI 584
>gi|170295802 estrogen receptor alpha isoform 3 [Homo sapiens]
Length = 595
Score = 30.0 bits (66), Expect = 4.6
Identities = 19/69 (27%), Positives = 32/69 (46%), Gaps = 1/69 (1%)
Query: 89 MKKKGFNYIYMKQCVESSPLVPIQQEWLDHMLRLIPESLKEGKEREELLESLINEVSSDF 148
M KG ++Y +C PL + E LD RL + + G EE +S + S
Sbjct: 517 MSNKGMEHLYSMKCKNVVPLYDLLLEMLD-AHRLHAPTSRGGASVEETDQSHLATAGSTS 575
Query: 149 ENSMKRYLV 157
+S+++Y +
Sbjct: 576 SHSLQKYYI 584
>gi|170295800 estrogen receptor alpha isoform 2 [Homo sapiens]
Length = 595
Score = 30.0 bits (66), Expect = 4.6
Identities = 19/69 (27%), Positives = 32/69 (46%), Gaps = 1/69 (1%)
Query: 89 MKKKGFNYIYMKQCVESSPLVPIQQEWLDHMLRLIPESLKEGKEREELLESLINEVSSDF 148
M KG ++Y +C PL + E LD RL + + G EE +S + S
Sbjct: 517 MSNKGMEHLYSMKCKNVVPLYDLLLEMLD-AHRLHAPTSRGGASVEETDQSHLATAGSTS 575
Query: 149 ENSMKRYLV 157
+S+++Y +
Sbjct: 576 SHSLQKYYI 584
>gi|62821794 estrogen receptor alpha isoform 1 [Homo sapiens]
Length = 595
Score = 30.0 bits (66), Expect = 4.6
Identities = 19/69 (27%), Positives = 32/69 (46%), Gaps = 1/69 (1%)
Query: 89 MKKKGFNYIYMKQCVESSPLVPIQQEWLDHMLRLIPESLKEGKEREELLESLINEVSSDF 148
M KG ++Y +C PL + E LD RL + + G EE +S + S
Sbjct: 517 MSNKGMEHLYSMKCKNVVPLYDLLLEMLD-AHRLHAPTSRGGASVEETDQSHLATAGSTS 575
Query: 149 ENSMKRYLV 157
+S+++Y +
Sbjct: 576 SHSLQKYYI 584
>gi|242117953 SH3 domain-containing protein C1orf113 isoform 1 [Homo
sapiens]
Length = 756
Score = 30.0 bits (66), Expect = 4.6
Identities = 24/85 (28%), Positives = 41/85 (48%), Gaps = 11/85 (12%)
Query: 65 LDRTLGKRT-PLLPPPDYPQTMT---------SEMKKKGFNYIYMKQCVES-SPLVPIQQ 113
++R ++T P+ PPPD +T+ +E K +G + ++ VES + + +
Sbjct: 649 IERAFAQKTRPIKPPPDSQETLALPSLVPQNYTENKNEGVDVTSLRGEVESLRRALELME 708
Query: 114 EWLDHMLRLIPESLKEGKEREELLE 138
L+ L I E LK KE+ LE
Sbjct: 709 VQLERKLTDIWEELKSEKEQRRRLE 733
>gi|242117948 SH3 domain-containing protein C1orf113 isoform 2 [Homo
sapiens]
Length = 645
Score = 30.0 bits (66), Expect = 4.6
Identities = 24/85 (28%), Positives = 41/85 (48%), Gaps = 11/85 (12%)
Query: 65 LDRTLGKRT-PLLPPPDYPQTMT---------SEMKKKGFNYIYMKQCVES-SPLVPIQQ 113
++R ++T P+ PPPD +T+ +E K +G + ++ VES + + +
Sbjct: 538 IERAFAQKTRPIKPPPDSQETLALPSLVPQNYTENKNEGVDVTSLRGEVESLRRALELME 597
Query: 114 EWLDHMLRLIPESLKEGKEREELLE 138
L+ L I E LK KE+ LE
Sbjct: 598 VQLERKLTDIWEELKSEKEQRRRLE 622
>gi|224586823 coiled-coil domain containing 110 isoform b [Homo
sapiens]
Length = 796
Score = 30.0 bits (66), Expect = 4.6
Identities = 39/182 (21%), Positives = 80/182 (43%), Gaps = 16/182 (8%)
Query: 5 NKAAIAAEKEALNLKLPPIVHLPENIGVDTP-TQSKLL----KYRRSKEQQQKINQLV-- 57
N I EKE L K ++ ++G + +Q +++ K R +K +Q+ + Q++
Sbjct: 540 NILLIQDEKEMLEKKTHQLLKEKSSLGNELKESQLEIIQLKEKERLAKTEQETLLQIIET 599
Query: 58 IDGAKRNLDRTLGKRTPLLPPPDYP----QTMTSEMKKKGFNYIYMKQCVESSPLVPIQQ 113
+ K NL+ TL + T + QT S ++ I K + +
Sbjct: 600 VKDEKLNLETTLQESTAARQIMEREIENIQTYQSTAEENFLQEI--KNAKSEASIYKNSL 657
Query: 114 EWLDHMLRLIPESLKEGKEREELLESLINEVSSD---FENSMKRYLVQSVLVKPPVKSLE 170
+ ++ + + E K ++L+ + + S + FENS+ R +L++ V+S+E
Sbjct: 658 SEIGKECEMLSKMVMETKTDNQILKEELKKHSQENIKFENSISRLTEDKILLENYVRSIE 717
Query: 171 DE 172
+E
Sbjct: 718 NE 719
>gi|22749515 coiled-coil domain containing 110 isoform a [Homo
sapiens]
Length = 833
Score = 30.0 bits (66), Expect = 4.6
Identities = 39/182 (21%), Positives = 80/182 (43%), Gaps = 16/182 (8%)
Query: 5 NKAAIAAEKEALNLKLPPIVHLPENIGVDTP-TQSKLL----KYRRSKEQQQKINQLV-- 57
N I EKE L K ++ ++G + +Q +++ K R +K +Q+ + Q++
Sbjct: 577 NILLIQDEKEMLEKKTHQLLKEKSSLGNELKESQLEIIQLKEKERLAKTEQETLLQIIET 636
Query: 58 IDGAKRNLDRTLGKRTPLLPPPDYP----QTMTSEMKKKGFNYIYMKQCVESSPLVPIQQ 113
+ K NL+ TL + T + QT S ++ I K + +
Sbjct: 637 VKDEKLNLETTLQESTAARQIMEREIENIQTYQSTAEENFLQEI--KNAKSEASIYKNSL 694
Query: 114 EWLDHMLRLIPESLKEGKEREELLESLINEVSSD---FENSMKRYLVQSVLVKPPVKSLE 170
+ ++ + + E K ++L+ + + S + FENS+ R +L++ V+S+E
Sbjct: 695 SEIGKECEMLSKMVMETKTDNQILKEELKKHSQENIKFENSISRLTEDKILLENYVRSIE 754
Query: 171 DE 172
+E
Sbjct: 755 NE 756
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.134 0.394
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,717,490
Number of Sequences: 37866
Number of extensions: 801247
Number of successful extensions: 2530
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 33
Number of HSP's that attempted gapping in prelim test: 2502
Number of HSP's gapped (non-prelim): 55
length of query: 457
length of database: 18,247,518
effective HSP length: 106
effective length of query: 351
effective length of database: 14,233,722
effective search space: 4996036422
effective search space used: 4996036422
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.