Search of human proteins with 8923900

Search of human proteins with 8923900

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|8923900 cytidine monophospho-N-acetylneuraminic acid
synthetase [Homo sapiens]
         (434 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|8923900 cytidine monophospho-N-acetylneuraminic acid syntheta...   880   0.0  
gi|169790958 methionine synthase reductase isoform 1 [Homo sapiens]    32   1.5  
gi|169790956 methionine synthase reductase isoform 2 [Homo sapiens]    32   1.5  
gi|61742786 leucine rich repeat and death domain containing prot...    32   1.5  
gi|197927446 sarcosine dehydrogenase precursor [Homo sapiens]          31   1.9  
gi|21361378 sarcosine dehydrogenase precursor [Homo sapiens]           31   1.9  
gi|208431817 protein kinase-like protein SgK493 [Homo sapiens]         31   1.9  
gi|146219843 Snf2-related CBP activator protein [Homo sapiens]         31   1.9  
gi|169636428 calicin [Homo sapiens]                                    31   2.5  
gi|239757677 PREDICTED: hypothetical protein [Homo sapiens]            30   3.3  
gi|239752167 PREDICTED: hypothetical protein [Homo sapiens]            30   3.3  
gi|239746688 PREDICTED: hypothetical protein [Homo sapiens]            30   3.3  
gi|146134341 hypothetical protein LOC133686 isoform 1 [Homo sapi...    30   3.3  
gi|187171277 DNA-directed DNA polymerase gamma [Homo sapiens]          30   4.3  
gi|4505937 DNA-directed DNA polymerase gamma [Homo sapiens]            30   4.3  
gi|239758117 PREDICTED: hypothetical protein [Homo sapiens]            30   4.3  
gi|30581135 structural maintenance of chromosomes 1A [Homo sapiens]    30   5.6  
gi|61742784 leucine rich repeat and death domain containing prot...    30   5.6  
gi|61742782 leucine rich repeat and death domain containing prot...    30   5.6  
gi|150418005 protein tyrosine phosphatase, non-receptor type 21 ...    29   9.5  
gi|9945439 septin 5 [Homo sapiens]                                     29   9.5  

>gi|8923900 cytidine monophospho-N-acetylneuraminic acid synthetase
           [Homo sapiens]
          Length = 434

 Score =  880 bits (2273), Expect = 0.0
 Identities = 434/434 (100%), Positives = 434/434 (100%)

Query: 1   MDSVEKGAATSVSNPRGRPSRGRPPKLQRNSRGGQGRGVEKPPHLAALILARGGSKGIPL 60
           MDSVEKGAATSVSNPRGRPSRGRPPKLQRNSRGGQGRGVEKPPHLAALILARGGSKGIPL
Sbjct: 1   MDSVEKGAATSVSNPRGRPSRGRPPKLQRNSRGGQGRGVEKPPHLAALILARGGSKGIPL 60

Query: 61  KNIKHLAGVPLIGWVLRAALDSGAFQSVWVSTDHDEIENVAKQFGAQVHRRSSEVSKDSS 120
           KNIKHLAGVPLIGWVLRAALDSGAFQSVWVSTDHDEIENVAKQFGAQVHRRSSEVSKDSS
Sbjct: 61  KNIKHLAGVPLIGWVLRAALDSGAFQSVWVSTDHDEIENVAKQFGAQVHRRSSEVSKDSS 120

Query: 121 TSLDAIIEFLNYHNEVDIVGNIQATSPCLHPTDLQKVAEMIREEGYDSVFSVVRRHQFRW 180
           TSLDAIIEFLNYHNEVDIVGNIQATSPCLHPTDLQKVAEMIREEGYDSVFSVVRRHQFRW
Sbjct: 121 TSLDAIIEFLNYHNEVDIVGNIQATSPCLHPTDLQKVAEMIREEGYDSVFSVVRRHQFRW 180

Query: 181 SEIQKGVREVTEPLNLNPAKRPRRQDWDGELYENGSFYFAKRHLIEMGYLQGGKMAYYEM 240
           SEIQKGVREVTEPLNLNPAKRPRRQDWDGELYENGSFYFAKRHLIEMGYLQGGKMAYYEM
Sbjct: 181 SEIQKGVREVTEPLNLNPAKRPRRQDWDGELYENGSFYFAKRHLIEMGYLQGGKMAYYEM 240

Query: 241 RAEHSVDIDVDIDWPIAEQRVLRYGYFGKEKLKEIKLLVCNIDGCLTNGHIYVSGDQKEI 300
           RAEHSVDIDVDIDWPIAEQRVLRYGYFGKEKLKEIKLLVCNIDGCLTNGHIYVSGDQKEI
Sbjct: 241 RAEHSVDIDVDIDWPIAEQRVLRYGYFGKEKLKEIKLLVCNIDGCLTNGHIYVSGDQKEI 300

Query: 301 ISYDVKDAIGISLLKKSGIEVRLISERACSKQTLSSLKLDCKMEVSVSDKLAVVDEWRKE 360
           ISYDVKDAIGISLLKKSGIEVRLISERACSKQTLSSLKLDCKMEVSVSDKLAVVDEWRKE
Sbjct: 301 ISYDVKDAIGISLLKKSGIEVRLISERACSKQTLSSLKLDCKMEVSVSDKLAVVDEWRKE 360

Query: 361 MGLCWKEVAYLGNEVSDEECLKRVGLSGAPADACSTAQKAVGYICKCNGGRGAIREFAEH 420
           MGLCWKEVAYLGNEVSDEECLKRVGLSGAPADACSTAQKAVGYICKCNGGRGAIREFAEH
Sbjct: 361 MGLCWKEVAYLGNEVSDEECLKRVGLSGAPADACSTAQKAVGYICKCNGGRGAIREFAEH 420

Query: 421 ICLLMEKVNNSCQK 434
           ICLLMEKVNNSCQK
Sbjct: 421 ICLLMEKVNNSCQK 434


>gi|169790958 methionine synthase reductase isoform 1 [Homo sapiens]
          Length = 698

 Score = 31.6 bits (70), Expect = 1.5
 Identities = 20/51 (39%), Positives = 31/51 (60%), Gaps = 7/51 (13%)

Query: 288 NGHIYVSGDQKEIISYDVKDAIGISLLKKSGIEVRLISERACSKQTLSSLK 338
           NGHIYV GD K  ++ DV DA+   + K+ G+      E+  + +TL++LK
Sbjct: 644 NGHIYVCGDAKN-MAKDVHDALVQIISKEVGV------EKLEAMKTLATLK 687


>gi|169790956 methionine synthase reductase isoform 2 [Homo sapiens]
          Length = 725

 Score = 31.6 bits (70), Expect = 1.5
 Identities = 20/51 (39%), Positives = 31/51 (60%), Gaps = 7/51 (13%)

Query: 288 NGHIYVSGDQKEIISYDVKDAIGISLLKKSGIEVRLISERACSKQTLSSLK 338
           NGHIYV GD K  ++ DV DA+   + K+ G+      E+  + +TL++LK
Sbjct: 671 NGHIYVCGDAKN-MAKDVHDALVQIISKEVGV------EKLEAMKTLATLK 714


>gi|61742786 leucine rich repeat and death domain containing protein
           isoform 3 [Homo sapiens]
          Length = 893

 Score = 31.6 bits (70), Expect = 1.5
 Identities = 33/134 (24%), Positives = 57/134 (42%), Gaps = 10/134 (7%)

Query: 60  LKNIKHLA----GVPL-IGWVLRAALDSGAFQSVWVSTDHDEIENVAKQFGAQVHRRSSE 114
           LKN+K ++     VP+ +     AA       ++W++T   ++  +    G++  RR + 
Sbjct: 698 LKNVKEVSFYRGAVPVRVPEEAEAARQRKGADALWMATLPIKLPRLR---GSEGPRRGAG 754

Query: 115 VSKDSSTSLDAIIEFLNYHNEVDIVGNIQATSPC--LHPTDLQKVAEMIREEGYDSVFSV 172
           +S       DA   FL   N + + G +    P   LH     +  + IR E  D +   
Sbjct: 755 LSLAPLNLGDAETGFLTQSNLLSVAGRLGLDWPAVALHLGVSYREVQRIRHEFRDDLDEQ 814

Query: 173 VRRHQFRWSEIQKG 186
           +R   F W+E Q G
Sbjct: 815 IRHMLFSWAERQAG 828


>gi|197927446 sarcosine dehydrogenase precursor [Homo sapiens]
          Length = 918

 Score = 31.2 bits (69), Expect = 1.9
 Identities = 31/106 (29%), Positives = 47/106 (44%), Gaps = 25/106 (23%)

Query: 1   MDSVEKGAATSVSNPRGRPSRGRPP---------------KLQRNSRGGQG-----RGVE 40
           M S+ +    + ++PR  P+RG  P                 QR  + GQG     +G  
Sbjct: 1   MASLSRALRVAAAHPRQSPTRGMGPCNLSSAAGPTAEKSVPYQRTLKEGQGTSVVAQGPS 60

Query: 41  KP-PHLAALILARGGSKGIPLKNIKHLAGVPLIGWVL--RAALDSG 83
           +P P  A +++  GGS G   + + HLA + + G VL  R  L SG
Sbjct: 61  RPLPSTANVVVIGGGSLG--CQTLYHLAKLGMSGAVLLERERLTSG 104


>gi|21361378 sarcosine dehydrogenase precursor [Homo sapiens]
          Length = 918

 Score = 31.2 bits (69), Expect = 1.9
 Identities = 31/106 (29%), Positives = 47/106 (44%), Gaps = 25/106 (23%)

Query: 1   MDSVEKGAATSVSNPRGRPSRGRPP---------------KLQRNSRGGQG-----RGVE 40
           M S+ +    + ++PR  P+RG  P                 QR  + GQG     +G  
Sbjct: 1   MASLSRALRVAAAHPRQSPTRGMGPCNLSSAAGPTAEKSVPYQRTLKEGQGTSVVAQGPS 60

Query: 41  KP-PHLAALILARGGSKGIPLKNIKHLAGVPLIGWVL--RAALDSG 83
           +P P  A +++  GGS G   + + HLA + + G VL  R  L SG
Sbjct: 61  RPLPSTANVVVIGGGSLG--CQTLYHLAKLGMSGAVLLERERLTSG 104


>gi|208431817 protein kinase-like protein SgK493 [Homo sapiens]
          Length = 493

 Score = 31.2 bits (69), Expect = 1.9
 Identities = 18/42 (42%), Positives = 23/42 (54%), Gaps = 1/42 (2%)

Query: 18 RPSRGRPPKLQRNSRGGQGRGVEKPPHLAALILARGGSKGIP 59
          R  R R  ++QR SRGG G G  +P     + LA GG  G+P
Sbjct: 58 RQIRARYEEVQRYSRGGPGPGAGRPERRRLMDLAPGG-PGLP 98


>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
          Length = 3230

 Score = 31.2 bits (69), Expect = 1.9
 Identities = 16/37 (43%), Positives = 22/37 (59%), Gaps = 1/37 (2%)

Query: 7    GAATSVSNPRGRPSRGRPPKLQRNSRGGQGRGVEKPP 43
            GA  +++ P  +  RGRPPK  R S    GRGV++ P
Sbjct: 2846 GALLAITPPAVKRRRGRPPKKNR-SPADAGRGVDEAP 2881


>gi|169636428 calicin [Homo sapiens]
          Length = 588

 Score = 30.8 bits (68), Expect = 2.5
 Identities = 23/83 (27%), Positives = 41/83 (49%), Gaps = 4/83 (4%)

Query: 195 NLNPAKRPRRQDWDGELYENGSFYFAKRH-LIEMGYLQGGKMAYYEMRAEHSVDIDVDID 253
           NLN  +R R++ WD  L  +   +FA R+ L  +  L    ++  +M+    + I +D  
Sbjct: 17  NLN-RQRKRKEYWDMALSVDNHVFFAHRNVLAAVSPLVRSLISSNDMKTADELFITIDTS 75

Query: 254 W--PIAEQRVLRYGYFGKEKLKE 274
           +  P+   ++L Y Y GK  + E
Sbjct: 76  YLSPVTVDQLLDYFYSGKVVISE 98


>gi|239757677 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 152

 Score = 30.4 bits (67), Expect = 3.3
 Identities = 24/89 (26%), Positives = 35/89 (39%), Gaps = 22/89 (24%)

Query: 7   GAATSVSNPRGRPSRGRPPKLQRNSRGGQGRGVEKPPHLAALILARGGSKGIPLKNIKHL 66
           G  TS S P  RP    PP   +          E PP L A   + GG   +P+ + +  
Sbjct: 44  GPRTSTSGPSHRPPPAPPPSSVQ----------ESPPQLPARNPSSGGHPPLPVPSRQTW 93

Query: 67  AGVPLIGWVLRAALDSGAFQSVWVSTDHD 95
            G+P+            A  S WVS++ +
Sbjct: 94  GGLPV------------ACASCWVSSERN 110


>gi|239752167 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 152

 Score = 30.4 bits (67), Expect = 3.3
 Identities = 24/89 (26%), Positives = 35/89 (39%), Gaps = 22/89 (24%)

Query: 7   GAATSVSNPRGRPSRGRPPKLQRNSRGGQGRGVEKPPHLAALILARGGSKGIPLKNIKHL 66
           G  TS S P  RP    PP   +          E PP L A   + GG   +P+ + +  
Sbjct: 44  GPRTSTSGPSHRPPPAPPPSSVQ----------ESPPQLPARNPSSGGHPPLPVPSRQTW 93

Query: 67  AGVPLIGWVLRAALDSGAFQSVWVSTDHD 95
            G+P+            A  S WVS++ +
Sbjct: 94  GGLPV------------ACASCWVSSERN 110


>gi|239746688 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 152

 Score = 30.4 bits (67), Expect = 3.3
 Identities = 24/89 (26%), Positives = 35/89 (39%), Gaps = 22/89 (24%)

Query: 7   GAATSVSNPRGRPSRGRPPKLQRNSRGGQGRGVEKPPHLAALILARGGSKGIPLKNIKHL 66
           G  TS S P  RP    PP   +          E PP L A   + GG   +P+ + +  
Sbjct: 44  GPRTSTSGPSHRPPPAPPPSSVQ----------ESPPQLPARNPSSGGHPPLPVPSRQTW 93

Query: 67  AGVPLIGWVLRAALDSGAFQSVWVSTDHD 95
            G+P+            A  S WVS++ +
Sbjct: 94  GGLPV------------ACASCWVSSERN 110


>gi|146134341 hypothetical protein LOC133686 isoform 1 [Homo
           sapiens]
          Length = 442

 Score = 30.4 bits (67), Expect = 3.3
 Identities = 23/78 (29%), Positives = 35/78 (44%), Gaps = 12/78 (15%)

Query: 258 EQRVLRYGYFGKEKLKEIKLLV-CNIDGCLTNGHIYVSGDQKEIISYDVKDAIGISLLKK 316
           EQ+  RY    +E LK++  L   +  G L   HI+    +  I S           L+ 
Sbjct: 83  EQQRYRYAELSEEDLKQLLALKGSSYSGLLERHHIHTKNVEHIIDS-----------LRN 131

Query: 317 SGIEVRLISERACSKQTL 334
            GIEVRL+  R   ++T+
Sbjct: 132 EGIEVRLVKRREYDEETV 149


>gi|187171277 DNA-directed DNA polymerase gamma [Homo sapiens]
          Length = 1239

 Score = 30.0 bits (66), Expect = 4.3
 Identities = 12/46 (26%), Positives = 23/46 (50%)

Query: 199 AKRPRRQDWDGELYENGSFYFAKRHLIEMGYLQGGKMAYYEMRAEH 244
           A  P ++DW  +L    +  F + H+ E   +QG +M + +  + H
Sbjct: 253 ASSPTQRDWQEQLVVGHNVSFDRAHIREQYLIQGSRMRFLDTMSMH 298


>gi|4505937 DNA-directed DNA polymerase gamma [Homo sapiens]
          Length = 1239

 Score = 30.0 bits (66), Expect = 4.3
 Identities = 12/46 (26%), Positives = 23/46 (50%)

Query: 199 AKRPRRQDWDGELYENGSFYFAKRHLIEMGYLQGGKMAYYEMRAEH 244
           A  P ++DW  +L    +  F + H+ E   +QG +M + +  + H
Sbjct: 253 ASSPTQRDWQEQLVVGHNVSFDRAHIREQYLIQGSRMRFLDTMSMH 298


>gi|239758117 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 465

 Score = 30.0 bits (66), Expect = 4.3
 Identities = 18/63 (28%), Positives = 30/63 (47%), Gaps = 6/63 (9%)

Query: 2   DSVEKGAATSVSNPRGRPSRGRPPKLQR------NSRGGQGRGVEKPPHLAALILARGGS 55
           D+V  G+    S P+ R   G+ P+ Q+       SRGG+G+  ++    AA   A+   
Sbjct: 129 DAVRSGSRVCRSRPQTRGGGGKQPRRQKAAVAGAKSRGGEGKKPQRRGQKAATAGAKSRG 188

Query: 56  KGI 58
            G+
Sbjct: 189 GGV 191


>gi|30581135 structural maintenance of chromosomes 1A [Homo sapiens]
          Length = 1233

 Score = 29.6 bits (65), Expect = 5.6
 Identities = 25/72 (34%), Positives = 37/72 (51%), Gaps = 3/72 (4%)

Query: 306 KDAIGISLLKKSGIE-VRLISERACSKQTLSSLKLDCKMEVSVSDKLAVVDEWRKEMGLC 364
           KD   I  LKK     +++I E     Q L +  L  K EV+  DK   ++E RK++G  
Sbjct: 844 KDENEIEKLKKEEQRHMKIIDETMAQLQDLKNQHLAKKSEVN--DKNHEMEEIRKKLGGA 901

Query: 365 WKEVAYLGNEVS 376
            KE+ +L  EV+
Sbjct: 902 NKEMTHLQKEVT 913


>gi|61742784 leucine rich repeat and death domain containing protein
           isoform 1 [Homo sapiens]
          Length = 910

 Score = 29.6 bits (65), Expect = 5.6
 Identities = 23/84 (27%), Positives = 35/84 (41%), Gaps = 2/84 (2%)

Query: 105 GAQVHRRSSEVSKDSSTSLDAIIEFLNYHNEVDIVGNIQATSPC--LHPTDLQKVAEMIR 162
           G++  RR + +S       DA   FL   N + + G +    P   LH     +  + IR
Sbjct: 762 GSEGPRRGAGLSLAPLNLGDAETGFLTQSNLLSVAGRLGLDWPAVALHLGVSYREVQRIR 821

Query: 163 EEGYDSVFSVVRRHQFRWSEIQKG 186
            E  D +   +R   F W+E Q G
Sbjct: 822 HEFRDDLDEQIRHMLFSWAERQAG 845


>gi|61742782 leucine rich repeat and death domain containing protein
           isoform 2 [Homo sapiens]
          Length = 753

 Score = 29.6 bits (65), Expect = 5.6
 Identities = 23/84 (27%), Positives = 35/84 (41%), Gaps = 2/84 (2%)

Query: 105 GAQVHRRSSEVSKDSSTSLDAIIEFLNYHNEVDIVGNIQATSPC--LHPTDLQKVAEMIR 162
           G++  RR + +S       DA   FL   N + + G +    P   LH     +  + IR
Sbjct: 605 GSEGPRRGAGLSLAPLNLGDAETGFLTQSNLLSVAGRLGLDWPAVALHLGVSYREVQRIR 664

Query: 163 EEGYDSVFSVVRRHQFRWSEIQKG 186
            E  D +   +R   F W+E Q G
Sbjct: 665 HEFRDDLDEQIRHMLFSWAERQAG 688


>gi|150418005 protein tyrosine phosphatase, non-receptor type 21
           [Homo sapiens]
          Length = 1174

 Score = 28.9 bits (63), Expect = 9.5
 Identities = 26/98 (26%), Positives = 53/98 (54%), Gaps = 10/98 (10%)

Query: 104 FGAQVHRRSSEVSKDSSTSLDAIIEFLNYHNE-VDIVGNIQATSPCLHPTDLQKVAEMI- 161
           FG ++ +R+   +  S + L A I+ LN  NE V+   ++++T        L+ VA+ + 
Sbjct: 5   FGLKL-KRTRRYTVSSKSCLVARIQLLN--NEFVEFTLSVESTGQ----ESLEAVAQRLE 57

Query: 162 -REEGYDSVFSVVRRHQFRWSEIQKGVREVTEPLNLNP 198
            RE  Y S++   +++Q RW +++K +++  +   L P
Sbjct: 58  LREVTYFSLWYYNKQNQRRWVDLEKPLKKQLDKYALEP 95


>gi|9945439 septin 5 [Homo sapiens]
          Length = 369

 Score = 28.9 bits (63), Expect = 9.5
 Identities = 15/32 (46%), Positives = 23/32 (71%), Gaps = 1/32 (3%)

Query: 133 HNEVDIVGNIQATSPCLHPTDLQKVAEMIREE 164
           H +V+IV  I A + CL P++++K+ E IREE
Sbjct: 179 HEKVNIVPLI-AKADCLVPSEIRKLKERIREE 209


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.135    0.404 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,870,229
Number of Sequences: 37866
Number of extensions: 779308
Number of successful extensions: 2324
Number of sequences better than 10.0: 21
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 17
Number of HSP's that attempted gapping in prelim test: 2315
Number of HSP's gapped (non-prelim): 21
length of query: 434
length of database: 18,247,518
effective HSP length: 105
effective length of query: 329
effective length of database: 14,271,588
effective search space: 4695352452
effective search space used: 4695352452
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.