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Search of human proteins with 8923894
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|8923894 thrombospondin type I domain-containing 1 isoform 1
[Homo sapiens]
(852 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|8923894 thrombospondin type I domain-containing 1 isoform 1 [... 1739 0.0
gi|40805852 thrombospondin type I domain-containing 1 isoform 2 ... 1517 0.0
gi|134031945 SCO-spondin [Homo sapiens] 58 3e-08
gi|145699139 cartilage intermediate layer protein 2 [Homo sapiens] 56 2e-07
gi|21265037 ADAM metallopeptidase with thrombospondin type 1 mot... 56 2e-07
gi|118572606 hemicentin 1 [Homo sapiens] 54 6e-07
gi|147904700 semaphorin 5A [Homo sapiens] 53 1e-06
gi|110825974 ADAM metallopeptidase with thrombospondin type 1 mo... 53 1e-06
gi|40317626 thrombospondin 1 precursor [Homo sapiens] 52 2e-06
gi|192449445 cartilage intermediate layer protein [Homo sapiens] 52 2e-06
gi|51558724 ADAM metallopeptidase with thrombospondin type 1 mot... 52 2e-06
gi|50845384 ADAM metallopeptidase with thrombospondin type 1 mot... 52 2e-06
gi|40317628 thrombospondin 2 precursor [Homo sapiens] 52 2e-06
gi|111118994 brain-specific angiogenesis inhibitor 1 precursor [... 51 4e-06
gi|91982767 semaphorin 5B isoform 1 [Homo sapiens] 51 4e-06
gi|115387099 brain-specific angiogenesis inhibitor 2 [Homo sapiens] 50 1e-05
gi|110611170 ADAM metallopeptidase with thrombospondin type 1 mo... 49 2e-05
gi|145309328 papilin [Homo sapiens] 49 2e-05
gi|21265058 a disintegrin-like and metalloprotease (reprolysin t... 49 2e-05
gi|21265052 ADAM metallopeptidase with thrombospondin type 1 mot... 49 2e-05
gi|110611167 ADAM metallopeptidase with thrombospondin type 1 mo... 49 2e-05
gi|110735441 ADAM metallopeptidase with thrombospondin type 1 mo... 49 2e-05
gi|40806187 ADAM metallopeptidase with thrombospondin type 1 mot... 49 3e-05
gi|223718260 ADAMTS-like 2 precursor [Homo sapiens] 48 3e-05
gi|41281450 ADAMTS-like 2 precursor [Homo sapiens] 48 3e-05
gi|4505737 complement factor properdin precursor [Homo sapiens] 48 3e-05
gi|223671861 complement factor properdin precursor [Homo sapiens] 48 3e-05
gi|4502359 brain-specific angiogenesis inhibitor 3 [Homo sapiens] 48 4e-05
gi|21265043 ADAM metallopeptidase with thrombospondin type 1 mot... 47 7e-05
gi|73695936 ADAM metallopeptidase with thrombospondin type 1 mot... 47 7e-05
>gi|8923894 thrombospondin type I domain-containing 1 isoform 1
[Homo sapiens]
Length = 852
Score = 1739 bits (4503), Expect = 0.0
Identities = 852/852 (100%), Positives = 852/852 (100%)
Query: 1 MKPMLKDFSNLLLVVLCDYVLGEAEYLLLREPGHVALSNDTVYVDFQYFDGANGTLRNVS 60
MKPMLKDFSNLLLVVLCDYVLGEAEYLLLREPGHVALSNDTVYVDFQYFDGANGTLRNVS
Sbjct: 1 MKPMLKDFSNLLLVVLCDYVLGEAEYLLLREPGHVALSNDTVYVDFQYFDGANGTLRNVS 60
Query: 61 VLLLEANTNQTVTTKYLLTNQSQGTLKFECFYFKEAGDYWFTMTPEATDNSTPFPWWEKS 120
VLLLEANTNQTVTTKYLLTNQSQGTLKFECFYFKEAGDYWFTMTPEATDNSTPFPWWEKS
Sbjct: 61 VLLLEANTNQTVTTKYLLTNQSQGTLKFECFYFKEAGDYWFTMTPEATDNSTPFPWWEKS 120
Query: 121 AFLKVEWPVFHVDLNRSAKAAEGTFQVGLFTSQPLCPFPVDKPNIVVDVIFTNSLPEARR 180
AFLKVEWPVFHVDLNRSAKAAEGTFQVGLFTSQPLCPFPVDKPNIVVDVIFTNSLPEARR
Sbjct: 121 AFLKVEWPVFHVDLNRSAKAAEGTFQVGLFTSQPLCPFPVDKPNIVVDVIFTNSLPEARR 180
Query: 181 NSRQPLEIRTSKRTELAQGQWVEFGCAPLGPEAYVTVVLKLLGRDSVITSTGPIDLAQKF 240
NSRQPLEIRTSKRTELAQGQWVEFGCAPLGPEAYVTVVLKLLGRDSVITSTGPIDLAQKF
Sbjct: 181 NSRQPLEIRTSKRTELAQGQWVEFGCAPLGPEAYVTVVLKLLGRDSVITSTGPIDLAQKF 240
Query: 241 GYKLVMVPELTCESGVEVTVLPPPCTFVQGVVTVFKEAPRYPGKRTIHLAENSLPLGERR 300
GYKLVMVPELTCESGVEVTVLPPPCTFVQGVVTVFKEAPRYPGKRTIHLAENSLPLGERR
Sbjct: 241 GYKLVMVPELTCESGVEVTVLPPPCTFVQGVVTVFKEAPRYPGKRTIHLAENSLPLGERR 300
Query: 301 TIFNCTLFDMGKNKYCFDFGISSRSHFSAKEECMLIQRNTETWGLWQPWSQCSATCGDGV 360
TIFNCTLFDMGKNKYCFDFGISSRSHFSAKEECMLIQRNTETWGLWQPWSQCSATCGDGV
Sbjct: 301 TIFNCTLFDMGKNKYCFDFGISSRSHFSAKEECMLIQRNTETWGLWQPWSQCSATCGDGV 360
Query: 361 RERRRVCLTSFPSSPVCPGMSLEASLCSLEECAAFQPSSPSPLQPQGPVKSNNIVTVTGI 420
RERRRVCLTSFPSSPVCPGMSLEASLCSLEECAAFQPSSPSPLQPQGPVKSNNIVTVTGI
Sbjct: 361 RERRRVCLTSFPSSPVCPGMSLEASLCSLEECAAFQPSSPSPLQPQGPVKSNNIVTVTGI 420
Query: 421 SLCLFIIIATVLITLWRRFGRPAKCSTPARHNSIHSPSFRKNSDEENICELSEQRGSFSD 480
SLCLFIIIATVLITLWRRFGRPAKCSTPARHNSIHSPSFRKNSDEENICELSEQRGSFSD
Sbjct: 421 SLCLFIIIATVLITLWRRFGRPAKCSTPARHNSIHSPSFRKNSDEENICELSEQRGSFSD 480
Query: 481 GGDGPTGSPGDTGIPLTYRRSGPVPPEDDASGSESFQSNAQKIIPPLFSYRLAQQQLKEM 540
GGDGPTGSPGDTGIPLTYRRSGPVPPEDDASGSESFQSNAQKIIPPLFSYRLAQQQLKEM
Sbjct: 481 GGDGPTGSPGDTGIPLTYRRSGPVPPEDDASGSESFQSNAQKIIPPLFSYRLAQQQLKEM 540
Query: 541 KKKGLTETTKVYHVSQSPLTDTAIDAAPSAPLDLESPEEAAANKFRIKSPFPEQPAVSAG 600
KKKGLTETTKVYHVSQSPLTDTAIDAAPSAPLDLESPEEAAANKFRIKSPFPEQPAVSAG
Sbjct: 541 KKKGLTETTKVYHVSQSPLTDTAIDAAPSAPLDLESPEEAAANKFRIKSPFPEQPAVSAG 600
Query: 601 ERPPSRLDLNVTQASCAISPSQTLIRKSQARHVGSRGGPSERSHARNAHFRRTASFHEAR 660
ERPPSRLDLNVTQASCAISPSQTLIRKSQARHVGSRGGPSERSHARNAHFRRTASFHEAR
Sbjct: 601 ERPPSRLDLNVTQASCAISPSQTLIRKSQARHVGSRGGPSERSHARNAHFRRTASFHEAR 660
Query: 661 QARPFRERSMSTLTPRQAPAYSSRTRTCEQAEDRFRPQSRGAHLFPEKLEHFQEASGTRG 720
QARPFRERSMSTLTPRQAPAYSSRTRTCEQAEDRFRPQSRGAHLFPEKLEHFQEASGTRG
Sbjct: 661 QARPFRERSMSTLTPRQAPAYSSRTRTCEQAEDRFRPQSRGAHLFPEKLEHFQEASGTRG 720
Query: 721 PLNPLPKSYTLGQPLRKPDLGDHQAGLVAGIERTEPHRARRGPSPSHKSVSRKQSSPISP 780
PLNPLPKSYTLGQPLRKPDLGDHQAGLVAGIERTEPHRARRGPSPSHKSVSRKQSSPISP
Sbjct: 721 PLNPLPKSYTLGQPLRKPDLGDHQAGLVAGIERTEPHRARRGPSPSHKSVSRKQSSPISP 780
Query: 781 KDNYQRVSSLSPSQCRKDKCQSFPTHPEFAFYDNTSFGLTEAEQRMLDLPGYFGSNEEDE 840
KDNYQRVSSLSPSQCRKDKCQSFPTHPEFAFYDNTSFGLTEAEQRMLDLPGYFGSNEEDE
Sbjct: 781 KDNYQRVSSLSPSQCRKDKCQSFPTHPEFAFYDNTSFGLTEAEQRMLDLPGYFGSNEEDE 840
Query: 841 TTSTLSVEKLVI 852
TTSTLSVEKLVI
Sbjct: 841 TTSTLSVEKLVI 852
>gi|40805852 thrombospondin type I domain-containing 1 isoform 2
[Homo sapiens]
Length = 799
Score = 1517 bits (3928), Expect = 0.0
Identities = 771/858 (89%), Positives = 777/858 (90%), Gaps = 65/858 (7%)
Query: 1 MKPMLKDFSNLLLVVLCDYVLGEAEYLLLREPGHVALSNDTVYVDFQYFDGANGTLRNVS 60
MKPMLKDFSNLLLVVLCDYVLGEAEYLLLREPGHVALSNDTVYVDFQYFDGANGTLRNVS
Sbjct: 1 MKPMLKDFSNLLLVVLCDYVLGEAEYLLLREPGHVALSNDTVYVDFQYFDGANGTLRNVS 60
Query: 61 VLLLEANTNQTVTTKYLLTNQSQGTLKFECFYFKEAGDYWFTMTPEATDNSTPFPWWEKS 120
VLLLEANTNQTVTTKYLLTNQSQGTLKFECFYFKEAGDYWFTMTPEATDNSTPFPWWEKS
Sbjct: 61 VLLLEANTNQTVTTKYLLTNQSQGTLKFECFYFKEAGDYWFTMTPEATDNSTPFPWWEKS 120
Query: 121 AFLKVEWPVFHVDLNRSAKAAEGTFQVGLFTSQPLCPFPVDKPNIVVDVIFTNSLPEARR 180
AFLKVEWPVFHVDLNRSAKAAEGTFQVGLFTSQPLCPFPVDKPNIVVDVIFTNSLPEARR
Sbjct: 121 AFLKVEWPVFHVDLNRSAKAAEGTFQVGLFTSQPLCPFPVDKPNIVVDVIFTNSLPEARR 180
Query: 181 NSRQPLEIRTSKRTELAQGQWVEFGCAPLGPEAYVTVVLKLLGRDSVITSTGPIDLAQKF 240
NSRQPLEIRTSKRTELAQGQWVEFGCAPLGPEAYVTVVLKLLGRDSVITSTGPIDLAQKF
Sbjct: 181 NSRQPLEIRTSKRTELAQGQWVEFGCAPLGPEAYVTVVLKLLGRDSVITSTGPIDLAQKF 240
Query: 241 GYKLVMVPELTCESGVEVTVLPPPCTFVQGVVTVFKEAPRYPGKRTIHLAENSLPLGERR 300
GYKLVMVPELTCESGVEVTVLPPPCTFVQGVVTVFKEAPRYPGKRTIHLAENSLPLGERR
Sbjct: 241 GYKLVMVPELTCESGVEVTVLPPPCTFVQGVVTVFKEAPRYPGKRTIHLAENSLPLGERR 300
Query: 301 TIFNCTLFDMGKNKYCFDFGISSRSHFSAKEECMLIQRNTETWGLWQPWSQCSATCGDGV 360
T+F N FD G
Sbjct: 301 -----TIF----NCTLFDMG---------------------------------------- 311
Query: 361 RERRRVCLTSFPSSPVCPGMSLEASLCSLEEC------AAFQPSSPSPLQPQGPVKSNNI 414
+ + C G+S + + EEC AFQPSSPSPLQPQGPVKSNNI
Sbjct: 312 --KNKYCFDF--------GISSRSHFSAKEECMLIQRNTAFQPSSPSPLQPQGPVKSNNI 361
Query: 415 VTVTGISLCLFIIIATVLITLWRRFGRPAKCSTPARHNSIHSPSFRKNSDEENICELSEQ 474
VTVTGISLCLFIIIATVLITLWRRFGRPAKCSTPARHNSIHSPSFRKNSDEENICELSEQ
Sbjct: 362 VTVTGISLCLFIIIATVLITLWRRFGRPAKCSTPARHNSIHSPSFRKNSDEENICELSEQ 421
Query: 475 RGSFSDGGDGPTGSPGDTGIPLTYRRSGPVPPEDDASGSESFQSNAQKIIPPLFSYRLAQ 534
RGSFSDGGDGPTGSPGDTGIPLTYRRSGPVPPEDDASGSESFQSNAQKIIPPLFSYRLAQ
Sbjct: 422 RGSFSDGGDGPTGSPGDTGIPLTYRRSGPVPPEDDASGSESFQSNAQKIIPPLFSYRLAQ 481
Query: 535 QQLKEMKKKGLTETTKVYHVSQSPLTDTAIDAAPSAPLDLESPEEAAANKFRIKSPFPEQ 594
QQLKEMKKKGLTETTKVYHVSQSPLTDTAIDAAPSAPLDLESPEEAAANKFRIKSPFPEQ
Sbjct: 482 QQLKEMKKKGLTETTKVYHVSQSPLTDTAIDAAPSAPLDLESPEEAAANKFRIKSPFPEQ 541
Query: 595 PAVSAGERPPSRLDLNVTQASCAISPSQTLIRKSQARHVGSRGGPSERSHARNAHFRRTA 654
PAVSAGERPPSRLDLNVTQASCAISPSQTLIRKSQARHVGSRGGPSERSHARNAHFRRTA
Sbjct: 542 PAVSAGERPPSRLDLNVTQASCAISPSQTLIRKSQARHVGSRGGPSERSHARNAHFRRTA 601
Query: 655 SFHEARQARPFRERSMSTLTPRQAPAYSSRTRTCEQAEDRFRPQSRGAHLFPEKLEHFQE 714
SFHEARQARPFRERSMSTLTPRQAPAYSSRTRTCEQAEDRFRPQSRGAHLFPEKLEHFQE
Sbjct: 602 SFHEARQARPFRERSMSTLTPRQAPAYSSRTRTCEQAEDRFRPQSRGAHLFPEKLEHFQE 661
Query: 715 ASGTRGPLNPLPKSYTLGQPLRKPDLGDHQAGLVAGIERTEPHRARRGPSPSHKSVSRKQ 774
ASGTRGPLNPLPKSYTLGQPLRKPDLGDHQAGLVAGIERTEPHRARRGPSPSHKSVSRKQ
Sbjct: 662 ASGTRGPLNPLPKSYTLGQPLRKPDLGDHQAGLVAGIERTEPHRARRGPSPSHKSVSRKQ 721
Query: 775 SSPISPKDNYQRVSSLSPSQCRKDKCQSFPTHPEFAFYDNTSFGLTEAEQRMLDLPGYFG 834
SSPISPKDNYQRVSSLSPSQCRKDKCQSFPTHPEFAFYDNTSFGLTEAEQRMLDLPGYFG
Sbjct: 722 SSPISPKDNYQRVSSLSPSQCRKDKCQSFPTHPEFAFYDNTSFGLTEAEQRMLDLPGYFG 781
Query: 835 SNEEDETTSTLSVEKLVI 852
SNEEDETTSTLSVEKLVI
Sbjct: 782 SNEEDETTSTLSVEKLVI 799
>gi|134031945 SCO-spondin [Homo sapiens]
Length = 5147
Score = 58.2 bits (139), Expect = 3e-08
Identities = 23/57 (40%), Positives = 30/57 (52%)
Query: 343 WGLWQPWSQCSATCGDGVRERRRVCLTSFPSSPVCPGMSLEASLCSLEECAAFQPSS 399
WGLW PWS CSA C G++ R R C + P CPG + C+ + C A P +
Sbjct: 2833 WGLWAPWSTCSAPCDGGIQTRGRSCSSLAPGDTTCPGPHSQTRDCNTQPCTAQCPEN 2889
Score = 56.6 bits (135), Expect = 9e-08
Identities = 32/96 (33%), Positives = 44/96 (45%), Gaps = 9/96 (9%)
Query: 329 AKEECMLIQRNTET--WGLWQPWSQCSATCGDGVRERRRVC-------LTSFPSSPVCPG 379
A+EE L+Q WG W PWS CS +CG G+R R R C L + P G
Sbjct: 3239 AEEEPCLLQGCDRAGGWGPWGPWSHCSRSCGGGLRSRTRACDQPPPQGLGDYCEGPRAQG 3298
Query: 380 MSLEASLCSLEECAAFQPSSPSPLQPQGPVKSNNIV 415
+A C + C A + + SP P P +++V
Sbjct: 3299 EVCQALPCPVTNCTAIEGAEYSPCGPPCPRSCDDLV 3334
Score = 51.2 bits (121), Expect = 4e-06
Identities = 20/53 (37%), Positives = 30/53 (56%), Gaps = 2/53 (3%)
Query: 343 WGLWQPWSQCSATCGDGVRERRRVCLTSFPSS--PVCPGMSLEASLCSLEECA 393
W +W+ W CS +CG G + R+R C+ P + CPG S E + C L+ C+
Sbjct: 2558 WAMWEAWGPCSVSCGGGHQSRQRSCVDPPPKNGGAPCPGASQERAPCGLQPCS 2610
Score = 47.4 bits (111), Expect = 6e-05
Identities = 25/65 (38%), Positives = 29/65 (44%), Gaps = 14/65 (21%)
Query: 342 TWGLWQPWSQCSATCGDGVRERRRVCLTS---FPS-----------SPVCPGMSLEASLC 387
TW W PWSQCSA+CG R R C S PS +P+C G E C
Sbjct: 3185 TWSPWTPWSQCSASCGPARCHRHRFCARSPSAVPSTVAPLPLPATPTPLCSGPEAEEEPC 3244
Query: 388 SLEEC 392
L+ C
Sbjct: 3245 LLQGC 3249
Score = 47.4 bits (111), Expect = 6e-05
Identities = 19/50 (38%), Positives = 26/50 (52%), Gaps = 5/50 (10%)
Query: 343 WGLWQPWSQCSATCGDGVRERRRVCLTSFPSSPVCPGMSLEASLCSLEEC 392
W W PW CS +CG G + R R C + P CPG + ++ CS + C
Sbjct: 3648 WSSWGPWEDCSVSCGGGEQLRSRRC-----ARPPCPGPARQSRTCSTQVC 3692
Score = 44.3 bits (103), Expect = 5e-04
Identities = 28/79 (35%), Positives = 33/79 (41%), Gaps = 20/79 (25%)
Query: 343 WGLWQPWSQCSATCGDGV----RERRRVCLT-------------SFPSS---PVCPGMSL 382
WG W WS CS +C D R R R+CL + PS PVCPG
Sbjct: 3883 WGPWSSWSPCSRSCTDPARPAWRSRTRLCLANCTMGDPLQERPCNLPSCTELPVCPGPGC 3942
Query: 383 EASLCSLEECAAFQPSSPS 401
A CS A ++P S S
Sbjct: 3943 GAGNCSWTSWAPWEPCSRS 3961
Score = 42.0 bits (97), Expect = 0.002
Identities = 21/53 (39%), Positives = 28/53 (52%), Gaps = 4/53 (7%)
Query: 343 WGLWQPWSQCSATCGDGVRERRRVCLTSFPSS---PVCPGMSLEASLCSLEEC 392
W W WS CS +C G+R R R T+ P++ C G ++EA CSL C
Sbjct: 2988 WSPWTLWSLCSCSCNVGIRRRFRAG-TAPPAAFGGAECQGPTMEAEFCSLRPC 3039
Score = 42.0 bits (97), Expect = 0.002
Identities = 23/59 (38%), Positives = 28/59 (47%), Gaps = 4/59 (6%)
Query: 343 WGLWQPWSQCSATCGDGVRERRRVCLTSFPS---SPVCPGMSLEASLCSLEECAAFQPS 398
W W PWS C +CG G R R C +S PS C G +A LC+ C A P+
Sbjct: 4007 WSRWSPWSWCDRSCGGGQSLRSRSC-SSPPSKNGGAPCAGERHQARLCNPMPCEAGCPA 4064
Score = 42.0 bits (97), Expect = 0.002
Identities = 18/41 (43%), Positives = 21/41 (51%), Gaps = 2/41 (4%)
Query: 341 ETWGLWQPWSQCSATCGDGVRERRRVCLTSFP--SSPVCPG 379
E W LW WS C +CG G + R R C + P SP C G
Sbjct: 4254 EAWTLWSSWSDCPVSCGGGNQVRTRACRAAAPHHRSPPCLG 4294
Score = 41.2 bits (95), Expect = 0.004
Identities = 21/55 (38%), Positives = 23/55 (41%), Gaps = 2/55 (3%)
Query: 344 GLWQPWSQCSATCGDGVRERRRVCLTSFPSSPVCPGMSLE-ASLCSLEECAAFQP 397
G W WS CSA CG G ER R C P C E C+L+ C P
Sbjct: 4767 GPWSAWSSCSAPCGGGTMERHRTC-EGGPGVAPCQAQDTEQRQECNLQPCPECPP 4820
Score = 39.7 bits (91), Expect = 0.012
Identities = 20/57 (35%), Positives = 24/57 (42%), Gaps = 13/57 (22%)
Query: 343 WGLWQPWSQCSATCGDGVRERRRVCLTSFPSSPV-------CPGMSLEASLCSLEEC 392
WG W PW CS TCG + R R C SP+ CPG ++ C C
Sbjct: 1697 WGPWSPWGPCSRTCGPWGQGRSRRC------SPLGLLVLQNCPGPEHQSQACFTAAC 1747
Score = 39.7 bits (91), Expect = 0.012
Identities = 18/54 (33%), Positives = 23/54 (42%), Gaps = 3/54 (5%)
Query: 342 TWGLWQPWSQCSATCGDGVRERRRVCLTSFPSSPVCPGMSL---EASLCSLEEC 392
+W W PW CS +CG G + R R P CP + E C+L C
Sbjct: 3948 SWTSWAPWEPCSRSCGVGQQRRLRAYRPPGPGGHWCPNILTAYQERRFCNLRAC 4001
Score = 39.3 bits (90), Expect = 0.016
Identities = 20/55 (36%), Positives = 25/55 (45%), Gaps = 7/55 (12%)
Query: 343 WGLWQPWSQCSATC-----GDGVRERRRVCLTSFPSSPVCPGMSLEASLCSLEEC 392
W W WS CS +C G G R R R+C + P CPG + + CS C
Sbjct: 2775 WTPWTSWSSCSQSCLAPGGGPGWRSRSRLCPS--PGDSSCPGDATQEEPCSPPVC 2827
Score = 39.3 bits (90), Expect = 0.016
Identities = 21/54 (38%), Positives = 23/54 (42%), Gaps = 10/54 (18%)
Query: 344 GLWQPWSQCSATCGDGVRERRRVCLTSFPSSPVCPGMSLEASLCSLEECAAFQP 397
G W PWS CS CG G R R R S +E S C L+ CA P
Sbjct: 3044 GEWGPWSPCSVPCGGGYRNRTRGSSRSL----------MEFSTCGLQPCAGPVP 3087
Score = 38.9 bits (89), Expect = 0.020
Identities = 21/64 (32%), Positives = 30/64 (46%), Gaps = 4/64 (6%)
Query: 343 WGLWQPWSQCSATCGD-GVRERRRVCLTSFP--SSPVCPGMSLEASLCSLEECAAFQPSS 399
+G W PW CS +CG G R R R C+ + P S C G + C +C + S+
Sbjct: 3814 FGPWSPWGPCSRSCGGLGTRTRSRQCVLTMPTLSGQGCRGPRQDLE-CPSPDCPGAEGST 3872
Query: 400 PSPL 403
P+
Sbjct: 3873 VEPV 3876
Score = 36.6 bits (83), Expect = 0.10
Identities = 25/77 (32%), Positives = 29/77 (37%), Gaps = 19/77 (24%)
Query: 343 WGLWQPWSQCSATCGDGVRERRRVC----------------LTSFPSSPVCPGMSLEASL 386
W W PWS CS C G R+R C L S + CP +
Sbjct: 1753 WSTWSPWSVCSEPC-RGTMTRQRQCHSPQNGGRTCAALPGGLHSTRQTKPCPQDGCPNAT 1811
Query: 387 CSLEECAAFQPSSPSPL 403
CS E FQP +P PL
Sbjct: 1812 CSGE--LMFQPCAPCPL 1826
Score = 34.3 bits (77), Expect = 0.50
Identities = 14/33 (42%), Positives = 17/33 (51%), Gaps = 5/33 (15%)
Query: 343 WGLWQPWSQCSATCGDGVRERRRVCLTSFPSSP 375
W W W+ C +CG GVR R R PS+P
Sbjct: 2718 WSAWSSWAPCDRSCGSGVRARFR-----SPSNP 2745
Score = 33.9 bits (76), Expect = 0.66
Identities = 22/65 (33%), Positives = 28/65 (43%), Gaps = 8/65 (12%)
Query: 343 WGLWQPWSQCSATCGDGVRERRRVCLTSFPSSPVCPGMSLEASLCSLEECAAFQPSSPSP 402
W W WS CS +CG ++ R TS +P C ++ C QPS P P
Sbjct: 4162 WSHWSAWSPCSHSCGPRGQQSRFRSSTSGSWAPECREEQSQSQPCP-------QPSCP-P 4213
Query: 403 LQPQG 407
L QG
Sbjct: 4214 LCLQG 4218
Score = 33.5 bits (75), Expect = 0.86
Identities = 12/23 (52%), Positives = 12/23 (52%)
Query: 343 WGLWQPWSQCSATCGDGVRERRR 365
W LW PWS C C G R R R
Sbjct: 4618 WSLWGPWSPCQVPCSGGFRLRWR 4640
Score = 32.7 bits (73), Expect = 1.5
Identities = 21/69 (30%), Positives = 24/69 (34%), Gaps = 8/69 (11%)
Query: 343 WGLWQPWSQCSATCGDGVRERRRVCLTSFPSSP----VCPGMSLEASLCSLEECAAFQPS 398
WG W PWS C G R R C S P +P CPG ++ C
Sbjct: 3475 WGPWGPWSPCDMCLGQS--HRSRAC--SRPPTPEGGRPCPGNHTQSRPCQENSTQCTDCG 3530
Query: 399 SPSPLQPQG 407
L P G
Sbjct: 3531 GGQSLHPCG 3539
Score = 32.3 bits (72), Expect = 1.9
Identities = 14/47 (29%), Positives = 21/47 (44%)
Query: 346 WQPWSQCSATCGDGVRERRRVCLTSFPSSPVCPGMSLEASLCSLEEC 392
W WS CS +CG G+ +R+ L CP + C ++ C
Sbjct: 2506 WSVWSSCSRSCGLGLTFQRQELLRPPLPGGSCPRDRFRSQSCFVQAC 2552
Score = 31.2 bits (69), Expect = 4.3
Identities = 16/53 (30%), Positives = 22/53 (41%), Gaps = 3/53 (5%)
Query: 343 WGLWQPWSQCSATCG-DGVRERRRVCLTSFPS--SPVCPGMSLEASLCSLEEC 392
W W PW++C CG ++ R PS C G+ +A C E C
Sbjct: 1912 WSSWSPWAKCLGPCGSQSIQWSFRSSNNPRPSGRGRQCRGIHRKARRCQTEPC 1964
Score = 31.2 bits (69), Expect = 4.3
Identities = 15/44 (34%), Positives = 17/44 (38%), Gaps = 2/44 (4%)
Query: 343 WGLWQPWSQCSATCGDGVRERRRVCLTSFP--SSPVCPGMSLEA 384
W W W+ CS C R R R C P C G + EA
Sbjct: 3411 WCPWSEWTMCSQPCRGQTRSRSRACACPTPQHGGAPCTGEAGEA 3454
Score = 30.8 bits (68), Expect = 5.6
Identities = 10/22 (45%), Positives = 12/22 (54%)
Query: 346 WQPWSQCSATCGDGVRERRRVC 367
W PW CS +CG G+ R C
Sbjct: 4313 WGPWGPCSRSCGPGLASRSGSC 4334
>gi|145699139 cartilage intermediate layer protein 2 [Homo sapiens]
Length = 1156
Score = 55.8 bits (133), Expect = 2e-07
Identities = 24/51 (47%), Positives = 28/51 (54%), Gaps = 2/51 (3%)
Query: 342 TWGLWQPWSQCSATCGDGVRERRRVCLTSFPSSPVCPGMSLEASLCSLEEC 392
+WG W PW CS +CG G R RRR C + P+ CPG LEA C C
Sbjct: 148 SWGAWGPWGPCSGSCGPGRRLRRRHCPS--PAGDACPGRPLEAQKCVRPRC 196
>gi|21265037 ADAM metallopeptidase with thrombospondin type 1 motif,
3 proprotein [Homo sapiens]
Length = 1205
Score = 55.8 bits (133), Expect = 2e-07
Identities = 25/58 (43%), Positives = 30/58 (51%), Gaps = 2/58 (3%)
Query: 337 QRNTETWGLWQPWSQCSATCGDGVRERRRVCLTSFP--SSPVCPGMSLEASLCSLEEC 392
Q+ WG W + CS TCG GVR R R C P CPG++ E LC+ EEC
Sbjct: 548 QKQDGNWGSWTKFGSCSRTCGTGVRFRTRQCNNPMPINGGQDCPGVNFEYQLCNTEEC 605
Score = 34.3 bits (77), Expect = 0.50
Identities = 17/46 (36%), Positives = 23/46 (50%), Gaps = 5/46 (10%)
Query: 348 PWSQCSATCGDGVRERRRVCLTSFPSSPVCPGMSLEA-SLCSLEEC 392
PWS+CS TCG+G R+ +C + C G E+ C L C
Sbjct: 974 PWSECSVTCGEGTEVRQVLC----RAGDHCDGEKPESVRACQLPPC 1015
>gi|118572606 hemicentin 1 [Homo sapiens]
Length = 5635
Score = 53.9 bits (128), Expect = 6e-07
Identities = 21/53 (39%), Positives = 32/53 (60%), Gaps = 2/53 (3%)
Query: 342 TWGLWQPWSQCSATCGDGVRERRRVCLTSFP--SSPVCPGMSLEASLCSLEEC 392
+WG W WSQCSA+CG G + R+R+C P CPG + + + C+++ C
Sbjct: 4816 SWGSWHSWSQCSASCGGGEKTRKRLCDHPVPVKGGRPCPGDTTQVTRCNVQAC 4868
Score = 47.4 bits (111), Expect = 6e-05
Identities = 20/60 (33%), Positives = 27/60 (45%), Gaps = 2/60 (3%)
Query: 343 WGLWQPWSQCSATCGDGVRERRRVCLTSFP--SSPVCPGMSLEASLCSLEECAAFQPSSP 400
W W WS CS +CG G R+R R C P C G +++ C+ + C SP
Sbjct: 4703 WATWASWSACSVSCGGGARQRTRGCSDPVPQYGGRKCEGSDVQSDFCNSDPCPTHGNWSP 4762
Score = 47.0 bits (110), Expect = 7e-05
Identities = 18/52 (34%), Positives = 25/52 (48%), Gaps = 2/52 (3%)
Query: 343 WGLWQPWSQCSATCGDGVRERRRVCLTSFPS--SPVCPGMSLEASLCSLEEC 392
W WQPW CS +CG G + R R+C P+ C G + +C+ C
Sbjct: 4646 WSAWQPWGTCSESCGKGTQTRARLCNNPPPAFGGSYCDGAETQMQVCNERNC 4697
Score = 43.5 bits (101), Expect = 8e-04
Identities = 18/49 (36%), Positives = 25/49 (51%), Gaps = 2/49 (4%)
Query: 346 WQPWSQCSATCGDGVRERRRVCLTSFPSS--PVCPGMSLEASLCSLEEC 392
W W CS TCG G+++R R+C P++ C G LE C + C
Sbjct: 4535 WSAWRACSVTCGKGIQKRSRLCNQPLPANGGKPCQGSDLEMRNCQNKPC 4583
Score = 39.3 bits (90), Expect = 0.016
Identities = 20/66 (30%), Positives = 33/66 (50%), Gaps = 12/66 (18%)
Query: 342 TWGLWQPWSQCSATCGDGVRERRRVCLTSFPS----SPVCPGMSLEASLCSLEEC----- 392
+W W W +C+ +CG G + R R C + PS C G ++E +C++ C
Sbjct: 4588 SWSEWSLWEECTRSCGRGNQTRTRTC--NNPSVQHGGRPCEGNAVEIIMCNIRPCPVHGA 4645
Query: 393 -AAFQP 397
+A+QP
Sbjct: 4646 WSAWQP 4651
Score = 37.7 bits (86), Expect = 0.045
Identities = 17/52 (32%), Positives = 21/52 (40%), Gaps = 2/52 (3%)
Query: 343 WGLWQPWSQCSATCGDGVRERRRVCLTSFPSS--PVCPGMSLEASLCSLEEC 392
W W W CS TC G R R C PS+ C G + C+ + C
Sbjct: 4760 WSPWSGWGTCSRTCNGGQMRRYRTCDNPPPSNGGRACGGPDSQIQRCNTDMC 4811
>gi|147904700 semaphorin 5A [Homo sapiens]
Length = 1074
Score = 53.1 bits (126), Expect = 1e-06
Identities = 23/65 (35%), Positives = 35/65 (53%), Gaps = 3/65 (4%)
Query: 331 EECMLIQRNTE-TWGLWQPWSQCSATCGDGVRERRRVCLTSFPS--SPVCPGMSLEASLC 387
+EC ++ + W W PW++CSATCG G R R C P+ +C G+ E +LC
Sbjct: 831 QECNILPCPVDGVWSCWSPWTKCSATCGGGHYMRTRSCSNPAPAYGGDICLGLHTEEALC 890
Query: 388 SLEEC 392
+ + C
Sbjct: 891 NTQPC 895
Score = 52.8 bits (125), Expect = 1e-06
Identities = 20/58 (34%), Positives = 32/58 (55%), Gaps = 4/58 (6%)
Query: 343 WGLWQPWSQCSATCGDGVRERRRVCLTSFPSSPVCPGMSLEASLCSLEECAAFQPSSP 400
W W PW +C+A CG G++ RRR+C + P C G ++E C+ C + ++P
Sbjct: 656 WTGWGPWERCTAQCGGGIQARRRIC----ENGPDCAGCNVEYQSCNTNPCPELKKTTP 709
Score = 48.5 bits (114), Expect = 3e-05
Identities = 22/52 (42%), Positives = 26/52 (50%), Gaps = 2/52 (3%)
Query: 343 WGLWQPWSQCSATCGDGVRERRRVCLTSFP--SSPVCPGMSLEASLCSLEEC 392
W W WSQCS C G+R R+RVC P C G SLE C++ C
Sbjct: 787 WSAWTSWSQCSRDCSRGIRNRKRVCNNPEPKYGGMPCLGPSLEYQECNILPC 838
Score = 42.0 bits (97), Expect = 0.002
Identities = 18/47 (38%), Positives = 25/47 (53%), Gaps = 3/47 (6%)
Query: 341 ETWGLWQPWSQCSATCGDGVRERRRVCLTSFPSSPVCPGMSLEASLC 387
E+W W WS+C A+ GV+ R R C+ FP C G + E+ C
Sbjct: 897 ESWSEWSDWSECEAS---GVQVRARQCILLFPMGSQCSGNTTESRPC 940
Score = 41.6 bits (96), Expect = 0.003
Identities = 19/48 (39%), Positives = 23/48 (47%), Gaps = 2/48 (4%)
Query: 343 WGLWQPWSQCSATCGDGVRERRRVCLTSFP--SSPVCPGMSLEASLCS 388
W W WS CS TCG G + R+R C P VC G + E C+
Sbjct: 598 WTPWTSWSPCSTTCGIGFQVRQRSCSNPTPRHGGRVCVGQNREERYCN 645
Score = 31.2 bits (69), Expect = 4.3
Identities = 17/51 (33%), Positives = 24/51 (47%), Gaps = 5/51 (9%)
Query: 343 WGLWQPWSQCSATCGDGVRE---RRRVCLTSFPSSP--VCPGMSLEASLCS 388
+G+W PW+ C+ T G V R R C + P C G +E + CS
Sbjct: 543 FGVWSPWTPCTHTDGSAVGSCLCRTRSCDSPAPQCGGWQCEGPGMEIANCS 593
>gi|110825974 ADAM metallopeptidase with thrombospondin type 1
motif, 2 isoform 1 preproprotein [Homo sapiens]
Length = 1211
Score = 52.8 bits (125), Expect = 1e-06
Identities = 22/59 (37%), Positives = 33/59 (55%), Gaps = 2/59 (3%)
Query: 336 IQRNTETWGLWQPWSQCSATCGDGVRERRRVCLTSFPSS--PVCPGMSLEASLCSLEEC 392
I + +WG W P+ CS TCG GV+ R R C P++ C G++ + LCS ++C
Sbjct: 557 ILKRDGSWGAWSPFGSCSRTCGTGVKFRTRQCDNPHPANGGRTCSGLAYDFQLCSRQDC 615
Score = 43.9 bits (102), Expect = 6e-04
Identities = 23/52 (44%), Positives = 29/52 (55%), Gaps = 3/52 (5%)
Query: 344 GLWQ--PWSQCSATCGDGVRERRRVCLTSFPSSPVCPGMSLE-ASLCSLEEC 392
G W+ PWSQCS TCG+G +ER +C T+ S +C E A C L C
Sbjct: 977 GRWRAGPWSQCSVTCGNGTQERPVLCRTADDSFGICQEERPETARTCRLGPC 1028
>gi|40317626 thrombospondin 1 precursor [Homo sapiens]
Length = 1170
Score = 52.4 bits (124), Expect = 2e-06
Identities = 24/64 (37%), Positives = 31/64 (48%), Gaps = 2/64 (3%)
Query: 331 EECMLIQRNTETWGLWQPWSQCSATCGDGVRERRRVCLTSFP--SSPVCPGMSLEASLCS 388
+EC + W W PWS CS TCGDGV R R+C + P + C G + E C
Sbjct: 426 QECDKRFKQDGGWSHWSPWSSCSVTCGDGVITRIRLCNSPSPQMNGKPCEGEARETKACK 485
Query: 389 LEEC 392
+ C
Sbjct: 486 KDAC 489
Score = 50.8 bits (120), Expect = 5e-06
Identities = 21/52 (40%), Positives = 28/52 (53%), Gaps = 2/52 (3%)
Query: 343 WGLWQPWSQCSATCGDGVRERRRVCLTSFP--SSPVCPGMSLEASLCSLEEC 392
WG W PW CS TCG GV++R R+C P C G E +C+ ++C
Sbjct: 495 WGPWSPWDICSVTCGGGVQKRSRLCNNPTPQFGGKDCVGDVTENQICNKQDC 546
Score = 46.2 bits (108), Expect = 1e-04
Identities = 17/50 (34%), Positives = 29/50 (58%), Gaps = 3/50 (6%)
Query: 343 WGLWQPWSQCSATCGDGVRERRRVCLTSFPSSPVCPGMSLEASLCSLEEC 392
W W W+ CS +CG+G+++R R C + + C G S++ C ++EC
Sbjct: 382 WSPWSEWTSCSTSCGNGIQQRGRSCDS---LNNRCEGSSVQTRTCHIQEC 428
>gi|192449445 cartilage intermediate layer protein [Homo sapiens]
Length = 1184
Score = 52.4 bits (124), Expect = 2e-06
Identities = 27/67 (40%), Positives = 37/67 (55%), Gaps = 4/67 (5%)
Query: 336 IQRNTET-WGLWQPWSQCSATCGD-GVRERRRVCLTSFPSSPVCPGMSLEASLCSLEECA 393
++R+TE W W PWS+CSA CG GV+ R R+CL S +C S E C ++C
Sbjct: 144 LRRDTERIWSPWSPWSKCSAACGQTGVQTRTRICLAEMVS--LCSEASEEGQHCMGQDCT 201
Query: 394 AFQPSSP 400
A + P
Sbjct: 202 ACDLTCP 208
>gi|51558724 ADAM metallopeptidase with thrombospondin type 1 motif,
12 preproprotein [Homo sapiens]
Length = 1594
Score = 52.4 bits (124), Expect = 2e-06
Identities = 24/73 (32%), Positives = 35/73 (47%), Gaps = 6/73 (8%)
Query: 332 ECMLIQRNTET----WGLWQPWSQCSATCGDGVRERRRVCLTSFP--SSPVCPGMSLEAS 385
+C+ + + E+ WG W PWS CS TCG GV+ R+C P C G
Sbjct: 530 KCITVGKKPESIPGGWGRWSPWSHCSRTCGAGVQSAERLCNNPEPKFGGKYCTGERKRYR 589
Query: 386 LCSLEECAAFQPS 398
LC++ C + P+
Sbjct: 590 LCNVHPCRSEAPT 602
Score = 38.5 bits (88), Expect = 0.027
Identities = 22/64 (34%), Positives = 29/64 (45%), Gaps = 4/64 (6%)
Query: 349 WSQCSATCGDGVRERRRVCLTSFPSSPVCPGMSLEASLCSLEECAAFQPSSPSPLQPQGP 408
WS+CS +CG GVR R C + +LC L++C PSS L+P
Sbjct: 953 WSECSVSCGGGVRIRSVTCAKNHDEPCDVTRKPNSRALCGLQQC----PSSRRVLKPNKG 1008
Query: 409 VKSN 412
SN
Sbjct: 1009 TISN 1012
Score = 37.4 bits (85), Expect = 0.059
Identities = 17/31 (54%), Positives = 19/31 (61%), Gaps = 2/31 (6%)
Query: 339 NTETWGLWQ--PWSQCSATCGDGVRERRRVC 367
N E WQ PWSQCS +CG GV+ER C
Sbjct: 1420 NPEPCEAWQVEPWSQCSRSCGGGVQERGVFC 1450
Score = 35.4 bits (80), Expect = 0.23
Identities = 18/48 (37%), Positives = 21/48 (43%)
Query: 349 WSQCSATCGDGVRERRRVCLTSFPSSPVCPGMSLEASLCSLEECAAFQ 396
WS+CS TCG G RR C T S A C L CA ++
Sbjct: 1322 WSECSTTCGLGAYWRRVECSTQMDSDCAAIQRPDPAKRCHLRPCAGWK 1369
Score = 30.8 bits (68), Expect = 5.6
Identities = 11/25 (44%), Positives = 16/25 (64%), Gaps = 2/25 (8%)
Query: 346 WQ--PWSQCSATCGDGVRERRRVCL 368
WQ W++CS TCG G+R + C+
Sbjct: 828 WQYGHWTECSVTCGTGIRRQTAHCI 852
>gi|50845384 ADAM metallopeptidase with thrombospondin type 1 motif,
1 preproprotein [Homo sapiens]
Length = 967
Score = 52.0 bits (123), Expect = 2e-06
Identities = 27/87 (31%), Positives = 38/87 (43%), Gaps = 13/87 (14%)
Query: 311 GKNKYCFD---FGISSRSHFSAKEECMLIQRNTETWGLWQPWSQCSATCGDGVRERRRVC 367
G+ K+C + + R HF +WG+W PW CS TCG GV+ R C
Sbjct: 535 GEGKWCINGKCVNKTDRKHFDTPFH--------GSWGMWGPWGDCSRTCGGGVQYTMREC 586
Query: 368 LTSFPSS--PVCPGMSLEASLCSLEEC 392
P + C G + C+LE+C
Sbjct: 587 DNPVPKNGGKYCEGKRVRYRSCNLEDC 613
Score = 31.6 bits (70), Expect = 3.3
Identities = 13/26 (50%), Positives = 16/26 (61%), Gaps = 2/26 (7%)
Query: 346 WQ--PWSQCSATCGDGVRERRRVCLT 369
WQ WS CS TCG G ++R CL+
Sbjct: 912 WQLGEWSSCSKTCGKGYKKRSLKCLS 937
>gi|40317628 thrombospondin 2 precursor [Homo sapiens]
Length = 1172
Score = 52.0 bits (123), Expect = 2e-06
Identities = 23/60 (38%), Positives = 31/60 (51%), Gaps = 3/60 (5%)
Query: 333 CMLIQRNTETWGLWQPWSQCSATCGDGVRERRRVCLTSFPSSPVCPGMSLEASLCSLEEC 392
C+ E W W W+QCS TCG G ++R R C +S C G S++ CSL +C
Sbjct: 374 CLHSVDGEEGWSPWAEWTQCSVTCGSGTQQRGRSCDV---TSNTCLGPSIQTRACSLSKC 430
Score = 50.8 bits (120), Expect = 5e-06
Identities = 21/52 (40%), Positives = 26/52 (50%), Gaps = 2/52 (3%)
Query: 343 WGLWQPWSQCSATCGDGVRERRRVCLTSFP--SSPVCPGMSLEASLCSLEEC 392
W W PWS C+ TC G+RER RVC + P C G E +C+ C
Sbjct: 497 WSPWSPWSACTVTCAGGIRERTRVCNSPEPQYGGKACVGDVQERQMCNKRSC 548
Score = 44.7 bits (104), Expect = 4e-04
Identities = 27/86 (31%), Positives = 34/86 (39%), Gaps = 5/86 (5%)
Query: 320 GISSRSHFSAKEECMLIQRNTETWGLWQPWSQCSATCGDGVRERRRVCLTSFP--SSPVC 377
G S ++ + +C R W W PWS CS TCG G R R+C + P C
Sbjct: 417 GPSIQTRACSLSKCDTRIRQDGGWSHWSPWSSCSVTCGVGNITRIRLCNSPVPQMGGKNC 476
Query: 378 PGMSLEASLCSLEEC---AAFQPSSP 400
G E C C + P SP
Sbjct: 477 KGSGRETKACQGAPCPIDGRWSPWSP 502
>gi|111118994 brain-specific angiogenesis inhibitor 1 precursor
[Homo sapiens]
Length = 1584
Score = 51.2 bits (121), Expect = 4e-06
Identities = 24/74 (32%), Positives = 30/74 (40%), Gaps = 1/74 (1%)
Query: 320 GISSRSHFSAKEECMLIQRNTE-TWGLWQPWSQCSATCGDGVRERRRVCLTSFPSSPVCP 378
G + H+ +C L Q + W W W CS TCG G + R RVC F C
Sbjct: 501 GAECQGHWVETRDCFLQQCPVDGKWQAWASWGSCSVTCGAGSQRRERVCSGPFFGGAACQ 560
Query: 379 GMSLEASLCSLEEC 392
G E C + C
Sbjct: 561 GPQDEYRQCGTQRC 574
Score = 48.5 bits (114), Expect = 3e-05
Identities = 19/50 (38%), Positives = 24/50 (48%)
Query: 343 WGLWQPWSQCSATCGDGVRERRRVCLTSFPSSPVCPGMSLEASLCSLEEC 392
W W PWS CS+TCG G R+R R C C G + C++ C
Sbjct: 412 WDEWSPWSLCSSTCGRGFRDRTRTCRPPQFGGNPCEGPEKQTKFCNIALC 461
Score = 45.1 bits (105), Expect = 3e-04
Identities = 20/43 (46%), Positives = 27/43 (62%), Gaps = 1/43 (2%)
Query: 346 WQPWSQCSATCGDGVRERRRVCLTSFPSSPVCPGMSLEASLCS 388
W PWS CS+TCG+G + R R C++S S+ C G E LC+
Sbjct: 360 WSPWSVCSSTCGEGWQTRTRFCVSSSYSTQ-CSGPLREQRLCN 401
Score = 43.5 bits (101), Expect = 8e-04
Identities = 18/50 (36%), Positives = 24/50 (48%)
Query: 343 WGLWQPWSQCSATCGDGVRERRRVCLTSFPSSPVCPGMSLEASLCSLEEC 392
W W WS CSA+C G ++R R C C G +E C L++C
Sbjct: 470 WNEWSSWSACSASCSQGRQQRTRECNGPSYGGAECQGHWVETRDCFLQQC 519
Score = 42.7 bits (99), Expect = 0.001
Identities = 21/57 (36%), Positives = 28/57 (49%), Gaps = 7/57 (12%)
Query: 340 TETWGLWQPWSQCSATCGDGVRERRRVCLTSFPSSPV----CPGMSLEASLCSLEEC 392
T W LW W +C+ CG G++ R R CL P+ V C G+ E C+ E C
Sbjct: 261 TGGWKLWSLWGECTRDCGGGLQTRTRTCL---PAPGVEGGGCEGVLEEGRQCNREAC 314
>gi|91982767 semaphorin 5B isoform 1 [Homo sapiens]
Length = 1151
Score = 51.2 bits (121), Expect = 4e-06
Identities = 21/52 (40%), Positives = 29/52 (55%), Gaps = 2/52 (3%)
Query: 343 WGLWQPWSQCSATCGDGVRERRRVCLTSFPS--SPVCPGMSLEASLCSLEEC 392
W W WS CSA+CG G +R R C + PS +C G+ E +LC+ + C
Sbjct: 913 WSCWTSWSPCSASCGGGHYQRTRSCTSPAPSPGEDICLGLHTEEALCATQAC 964
Score = 47.8 bits (112), Expect = 4e-05
Identities = 20/58 (34%), Positives = 30/58 (51%), Gaps = 4/58 (6%)
Query: 343 WGLWQPWSQCSATCGDGVRERRRVCLTSFPSSPVCPGMSLEASLCSLEECAAFQPSSP 400
W W WS+CS+ CG G++ RRR C + C G +E C+ E C + ++P
Sbjct: 725 WASWGSWSKCSSNCGGGMQSRRRAC----ENGNSCLGCGVEFKTCNPEGCPEVRRNTP 778
Score = 43.9 bits (102), Expect = 6e-04
Identities = 35/132 (26%), Positives = 53/132 (40%), Gaps = 11/132 (8%)
Query: 330 KEECMLIQRNTETWGLWQPWSQCSATCGDGVRERRRVCLTSFPSSPVCPGMSLEASLCSL 389
+E Q E W W WS+C+ DG + R R C P S C G S ++ C
Sbjct: 955 EEALCATQACPEGWSPWSEWSKCT---DDGAQSRSRHCEELLPGSSACAGNSSQSRPCPY 1011
Query: 390 EECAAFQPSSPSPLQPQGPVKSNNIV--TVTGISLCLFIIIATVLITL----WRRFGRPA 443
E P+ S ++ N++ TGIS L + T+ + L +R + +
Sbjct: 1012 SEIPVILPA--SSMEEATDCAGFNLIHLVATGISCFLGSGLLTLAVYLSCQHCQRQSQES 1069
Query: 444 KCSTPARHNSIH 455
PA N +H
Sbjct: 1070 TLVHPATPNHLH 1081
Score = 41.2 bits (95), Expect = 0.004
Identities = 19/52 (36%), Positives = 24/52 (46%), Gaps = 2/52 (3%)
Query: 343 WGLWQPWSQCSATCGDGVRERRRVCLTSFPSSP--VCPGMSLEASLCSLEEC 392
W W PWS CS C G R R+R C P + C G + E C+ + C
Sbjct: 856 WAAWGPWSSCSRDCELGFRVRKRTCTNPEPRNGGLPCVGDAAEYQDCNPQAC 907
Score = 39.7 bits (91), Expect = 0.012
Identities = 17/48 (35%), Positives = 23/48 (47%), Gaps = 2/48 (4%)
Query: 343 WGLWQPWSQCSATCGDGVRERRRVCLTSFP--SSPVCPGMSLEASLCS 388
W W W+ CS +CG G + R+R C P +C G S E C+
Sbjct: 667 WTPWSSWALCSTSCGIGFQVRQRSCSNPAPRHGGRICVGKSREERFCN 714
>gi|115387099 brain-specific angiogenesis inhibitor 2 [Homo sapiens]
Length = 1585
Score = 49.7 bits (117), Expect = 1e-05
Identities = 20/50 (40%), Positives = 24/50 (48%)
Query: 343 WGLWQPWSQCSATCGDGVRERRRVCLTSFPSSPVCPGMSLEASLCSLEEC 392
W W WS CS +CG G R R R C+ C G L+ LCS+ C
Sbjct: 367 WEEWGSWSLCSRSCGRGSRSRMRTCVPPQHGGKACEGPELQTKLCSMAAC 416
Score = 48.1 bits (113), Expect = 3e-05
Identities = 21/53 (39%), Positives = 25/53 (47%)
Query: 343 WGLWQPWSQCSATCGDGVRERRRVCLTSFPSSPVCPGMSLEASLCSLEECAAF 395
WG W WS CS TC G + R R+C + C G E CS + C AF
Sbjct: 478 WGPWNAWSLCSKTCDTGWQRRFRMCQATGTQGYPCEGTGEEVKPCSEKRCPAF 530
Score = 47.4 bits (111), Expect = 6e-05
Identities = 19/52 (36%), Positives = 26/52 (50%)
Query: 343 WGLWQPWSQCSATCGDGVRERRRVCLTSFPSSPVCPGMSLEASLCSLEECAA 394
W W PW CS +C +G ++R R C + P+ C G + CS EC A
Sbjct: 422 WLEWGPWGPCSTSCANGTQQRSRKCSVAGPAWATCTGALTDTRECSNLECPA 473
Score = 44.3 bits (103), Expect = 5e-04
Identities = 19/43 (44%), Positives = 25/43 (58%), Gaps = 1/43 (2%)
Query: 346 WQPWSQCSATCGDGVRERRRVCLTSFPSSPVCPGMSLEASLCS 388
W PWS CS TCG G++ R R C++S P +C G E C+
Sbjct: 315 WSPWSVCSLTCGQGLQVRTRSCVSS-PYGTLCSGPLRETRPCN 356
>gi|110611170 ADAM metallopeptidase with thrombospondin type 1
motif, 17 preproprotein [Homo sapiens]
Length = 1095
Score = 49.3 bits (116), Expect = 2e-05
Identities = 24/58 (41%), Positives = 28/58 (48%), Gaps = 2/58 (3%)
Query: 343 WGLWQPWSQCSATCGDGVRERRRVC--LTSFPSSPVCPGMSLEASLCSLEECAAFQPS 398
W W WS CS TCG G R R+R C P CPG S+E ++C C PS
Sbjct: 546 WSPWGAWSMCSRTCGTGARFRQRKCDNPPPGPGGTHCPGASVEHAVCENLPCPKGLPS 603
Score = 36.2 bits (82), Expect = 0.13
Identities = 31/111 (27%), Positives = 43/111 (38%), Gaps = 9/111 (8%)
Query: 297 GERRTIFNCTLFDMGKNKYCFDFGISSRSHFSAKEECMLIQRNTETWGLWQPWSQCSATC 356
GERRTI +CT D S + + W + PWS CSATC
Sbjct: 819 GERRTIVSCTRIVNKTTTLVNDSDCPQASRPEPQVRRCNLHPCQSRW-VAGPWSPCSATC 877
Query: 357 GDGVRERRRVCL------TSFPSSPV-CPGMSLEA-SLCSLEECAAFQPSS 399
G + R C+ T + P+ CPG A C ++C + +S
Sbjct: 878 EKGFQHREVTCVYQLQNGTHVATRPLYCPGPRPAAVQSCEGQDCLSIWEAS 928
Score = 33.1 bits (74), Expect = 1.1
Identities = 14/28 (50%), Positives = 18/28 (64%), Gaps = 2/28 (7%)
Query: 345 LWQP--WSQCSATCGDGVRERRRVCLTS 370
+W+ WSQCSA+CG GV +R C S
Sbjct: 924 IWEASEWSQCSASCGKGVWKRTVACTNS 951
Score = 30.8 bits (68), Expect = 5.6
Identities = 17/48 (35%), Positives = 22/48 (45%), Gaps = 4/48 (8%)
Query: 349 WSQCSATCGDGVRERRRVCLTSFPS--SPVCPGMSLEASL--CSLEEC 392
WS CS+TCG G++ R C+ CP +S A C E C
Sbjct: 981 WSTCSSTCGKGLQSRVVQCMHKVTGRHGSECPALSKPAPYRQCYQEVC 1028
>gi|145309328 papilin [Homo sapiens]
Length = 1251
Score = 49.3 bits (116), Expect = 2e-05
Identities = 22/58 (37%), Positives = 28/58 (48%), Gaps = 1/58 (1%)
Query: 336 IQRNTETWGLWQPWSQCSATCGDGVRERRRVCLTS-FPSSPVCPGMSLEASLCSLEEC 392
++R ++TWG W WS CS TCG GV R R C + C G + C E C
Sbjct: 22 VRRQSDTWGPWSQWSPCSRTCGGGVSFRERPCYSQRRDGGSSCVGPARSHRSCRTESC 79
Score = 38.1 bits (87), Expect = 0.035
Identities = 19/60 (31%), Positives = 28/60 (46%), Gaps = 10/60 (16%)
Query: 348 PWSQCSATCGDGVRERRRVCLTSFPSS----------PVCPGMSLEASLCSLEECAAFQP 397
PW+ CSA+CG G + R C++S + PG C+L+ CAA+ P
Sbjct: 343 PWAPCSASCGGGSQSRSVYCISSDGAGIQEAVEEAECAGLPGKPPAIQACNLQRCAAWSP 402
Score = 36.2 bits (82), Expect = 0.13
Identities = 19/55 (34%), Positives = 26/55 (47%), Gaps = 9/55 (16%)
Query: 339 NTETWGLW--QPWSQCSATCGDGVRERRRVCLTSFPSSPVCPGMSLEASLCSLEE 391
N + W +PW +CS +CG GVR+R C G L + CSLE+
Sbjct: 393 NLQRCAAWSPEPWGECSVSCGVGVRKRSVTCRGE-------RGSLLHTAACSLED 440
Score = 31.6 bits (70), Expect = 3.3
Identities = 24/92 (26%), Positives = 40/92 (43%), Gaps = 14/92 (15%)
Query: 331 EECMLIQRNTETWGLWQPWSQCSATCGDGVRERRRVCLTSFPS--SPVCPGMSLEASLCS 388
E+C L+ + + W + W CS +C G R R+ +C PS + ++ C+
Sbjct: 451 EDCPLL--SDQAWHVGT-WGLCSKSCSSGTRRRQVICAIGPPSHCGSLQHSKPVDVEPCN 507
Query: 389 LEECAAFQ--PS-------SPSPLQPQGPVKS 411
+ C Q PS + +P P GP +S
Sbjct: 508 TQPCHLPQEVPSMQDVHTPASNPWMPLGPQES 539
>gi|21265058 a disintegrin-like and metalloprotease (reprolysin
type) with thrombospondin type 1 motif, 15 preproprotein
[Homo sapiens]
Length = 950
Score = 48.9 bits (115), Expect = 2e-05
Identities = 24/62 (38%), Positives = 33/62 (53%), Gaps = 6/62 (9%)
Query: 342 TWGLWQPWSQCSATCGDGVRERRRVCLTSFPSS--PVCPGMSLEASLCSLEECAAFQPSS 399
+W W P+ CS TCG GV+ RR C P++ C G+ ++ C+LE C PSS
Sbjct: 518 SWAKWDPYGPCSRTCGGGVQLARRQCTNPTPANGGKYCEGVRVKYRSCNLEPC----PSS 573
Query: 400 PS 401
S
Sbjct: 574 AS 575
Score = 30.4 bits (67), Expect = 7.3
Identities = 19/58 (32%), Positives = 28/58 (48%), Gaps = 5/58 (8%)
Query: 349 WSQCSATCGDGVRERRRVCLTSF--PSSPVCPG--MSLEASLCSLEECAAFQPSSPSP 402
W CSA+CG G+++R C S + P C +E C E C ++ S+ SP
Sbjct: 848 WGPCSASCGSGLQKRAVDCRGSAGQRTVPACDAAHRPVETQACG-EPCPTWELSAWSP 904
>gi|21265052 ADAM metallopeptidase with thrombospondin type 1 motif,
14 isoform 2 preproprotein [Homo sapiens]
Length = 1223
Score = 48.9 bits (115), Expect = 2e-05
Identities = 46/187 (24%), Positives = 63/187 (33%), Gaps = 52/187 (27%)
Query: 349 WSQCSATCGDGVRERRRVCLTSFPSSPVCPGMSLE-ASLCSLEECAAFQPSS-------- 399
WSQCSATCG+G+++R+ VC T+ S C G + +CSL C +S
Sbjct: 977 WSQCSATCGEGIQQRQVVCRTNANSLGHCEGDRPDTVQVCSLPACGGNHQNSTVRADVWE 1036
Query: 400 -----------PSPLQPQGPVKSNNIVTVTGISLCLFIIIATVLITLWRRFGRPAKCSTP 448
PL P + S T C ++ CS P
Sbjct: 1037 LGTPEGQWVPQSEPLHPINKISSTEPCTGDRSVFCQMEVL-------------DRYCSIP 1083
Query: 449 ARHNSIHSPSFRKNSDEENICELSEQRGSFSDGGDGPTGSPGDTGIPLTYRRSGPVP-PE 507
H +K S G P PG T +P P+P P+
Sbjct: 1084 GYHRLCCVSCIKKAS------------------GPNPGPDPGPTSLPPFSTPGSPLPGPQ 1125
Query: 508 DDASGSE 514
D A +E
Sbjct: 1126 DPADAAE 1132
Score = 45.1 bits (105), Expect = 3e-04
Identities = 20/52 (38%), Positives = 26/52 (50%), Gaps = 2/52 (3%)
Query: 343 WGLWQPWSQCSATCGDGVRERRRVCLTSFPS--SPVCPGMSLEASLCSLEEC 392
W W + CS +CG GVR R R C P+ +C G E +C+ EEC
Sbjct: 555 WSSWTKFGSCSRSCGGGVRSRSRSCNNPSPAYGGRLCLGPMFEYQVCNSEEC 606
>gi|110611167 ADAM metallopeptidase with thrombospondin type 1 motif,
14 isoform 1 preproprotein [Homo sapiens]
Length = 1226
Score = 48.9 bits (115), Expect = 2e-05
Identities = 46/187 (24%), Positives = 63/187 (33%), Gaps = 52/187 (27%)
Query: 349 WSQCSATCGDGVRERRRVCLTSFPSSPVCPGMSLE-ASLCSLEECAAFQPSS-------- 399
WSQCSATCG+G+++R+ VC T+ S C G + +CSL C +S
Sbjct: 980 WSQCSATCGEGIQQRQVVCRTNANSLGHCEGDRPDTVQVCSLPACGGNHQNSTVRADVWE 1039
Query: 400 -----------PSPLQPQGPVKSNNIVTVTGISLCLFIIIATVLITLWRRFGRPAKCSTP 448
PL P + S T C ++ CS P
Sbjct: 1040 LGTPEGQWVPQSEPLHPINKISSTEPCTGDRSVFCQMEVL-------------DRYCSIP 1086
Query: 449 ARHNSIHSPSFRKNSDEENICELSEQRGSFSDGGDGPTGSPGDTGIPLTYRRSGPVP-PE 507
H +K S G P PG T +P P+P P+
Sbjct: 1087 GYHRLCCVSCIKKAS------------------GPNPGPDPGPTSLPPFSTPGSPLPGPQ 1128
Query: 508 DDASGSE 514
D A +E
Sbjct: 1129 DPADAAE 1135
Score = 45.1 bits (105), Expect = 3e-04
Identities = 20/52 (38%), Positives = 26/52 (50%), Gaps = 2/52 (3%)
Query: 343 WGLWQPWSQCSATCGDGVRERRRVCLTSFPS--SPVCPGMSLEASLCSLEEC 392
W W + CS +CG GVR R R C P+ +C G E +C+ EEC
Sbjct: 558 WSSWTKFGSCSRSCGGGVRSRSRSCNNPSPAYGGRLCLGPMFEYQVCNSEEC 609
>gi|110735441 ADAM metallopeptidase with thrombospondin type 1
motif, 16 preproprotein [Homo sapiens]
Length = 1224
Score = 48.9 bits (115), Expect = 2e-05
Identities = 21/52 (40%), Positives = 26/52 (50%), Gaps = 2/52 (3%)
Query: 343 WGLWQPWSQCSATCGDGVRERRRVCLTSFPS--SPVCPGMSLEASLCSLEEC 392
W W WS CS TCG GV R R+C PS C G + LC+ ++C
Sbjct: 589 WSDWSSWSPCSRTCGGGVSHRSRLCTNPKPSHGGKFCEGSTRTLKLCNSQKC 640
Score = 35.4 bits (80), Expect = 0.23
Identities = 15/27 (55%), Positives = 18/27 (66%), Gaps = 2/27 (7%)
Query: 344 GLW--QPWSQCSATCGDGVRERRRVCL 368
G W PWSQC+A+CG GV+ R CL
Sbjct: 1128 GSWFASPWSQCTASCGGGVQTRSVQCL 1154
Score = 35.0 bits (79), Expect = 0.29
Identities = 13/27 (48%), Positives = 19/27 (70%)
Query: 348 PWSQCSATCGDGVRERRRVCLTSFPSS 374
PW++CS TCG G R+R C ++ PS+
Sbjct: 994 PWAECSHTCGKGWRKRAVACKSTNPSA 1020
>gi|40806187 ADAM metallopeptidase with thrombospondin type 1 motif,
18 preproprotein [Homo sapiens]
Length = 1221
Score = 48.5 bits (114), Expect = 3e-05
Identities = 21/52 (40%), Positives = 26/52 (50%), Gaps = 2/52 (3%)
Query: 343 WGLWQPWSQCSATCGDGVRERRRVCLTSFP--SSPVCPGMSLEASLCSLEEC 392
W W WS+CS TCG GV+ + R C P CPG S LC++ C
Sbjct: 592 WSAWSKWSECSRTCGGGVKFQERHCNNPKPQYGGLFCPGSSRIYQLCNINPC 643
Score = 38.1 bits (87), Expect = 0.035
Identities = 16/25 (64%), Positives = 18/25 (72%), Gaps = 1/25 (4%)
Query: 343 WGLWQPWSQCSATCGDGVRERRRVC 367
W L PWSQCS TCG GVR+R +C
Sbjct: 995 WSLG-PWSQCSKTCGRGVRKRELLC 1018
Score = 36.2 bits (82), Expect = 0.13
Identities = 26/79 (32%), Positives = 38/79 (48%), Gaps = 15/79 (18%)
Query: 330 KEECML--IQRNTETWGLWQPWSQCSATCGDGVRERRRVC--------LTSFPS----SP 375
+E C+L +N+ + WS+CSATCG GVR+R C L +FP +
Sbjct: 1040 QEGCVLGRCPKNSRLQWVASSWSECSATCGLGVRKREMKCSEKGFQGKLITFPERRCRNI 1099
Query: 376 VCPGMSLEASLCSLEECAA 394
P + LE + C+ C A
Sbjct: 1100 KKPNLDLEET-CNRRACPA 1117
Score = 32.7 bits (73), Expect = 1.5
Identities = 13/30 (43%), Positives = 16/30 (53%)
Query: 348 PWSQCSATCGDGVRERRRVCLTSFPSSPVC 377
PW QC+ TCG GV+ R C+ S C
Sbjct: 1131 PWQQCTVTCGGGVQTRSVHCVQQGRPSSSC 1160
Score = 30.4 bits (67), Expect = 7.3
Identities = 20/67 (29%), Positives = 31/67 (46%), Gaps = 12/67 (17%)
Query: 337 QRNTETWGLWQPWSQCSATCGDGVRERRRVCL--------TSFPSSPVCPGMSLEASLCS 388
+R TW + Q S+CS +CG G + +CL +SF S+ P E +C+
Sbjct: 872 KRPAYTWSIVQ--SECSVSCGGGYINVKAICLRDQNTQVNSSFCSAKTKP--VTEPKICN 927
Query: 389 LEECAAF 395
C A+
Sbjct: 928 AFSCPAY 934
>gi|223718260 ADAMTS-like 2 precursor [Homo sapiens]
Length = 951
Score = 48.1 bits (113), Expect = 3e-05
Identities = 21/56 (37%), Positives = 27/56 (48%), Gaps = 6/56 (10%)
Query: 343 WGLWQPWSQCSATCGDGVRERRRVCL------TSFPSSPVCPGMSLEASLCSLEEC 392
WG W W+ CS +CG GV + R CL P + C G S LC ++EC
Sbjct: 50 WGEWTKWTACSRSCGGGVTSQERHCLQQRRKSVPGPGNRTCTGTSKRYQLCRVQEC 105
Score = 36.2 bits (82), Expect = 0.13
Identities = 26/95 (27%), Positives = 34/95 (35%), Gaps = 8/95 (8%)
Query: 331 EECMLIQRNTETWGLWQPWSQCSATCGDGVRERRRVCLTSFPSSPVCPGM--SLEASLCS 388
EE +R W PWS+C+ TCG GVR R C C + + C
Sbjct: 845 EESTCFERPCFKW-YTSPWSECTKTCGVGVRMRDVKCYQGTDIVRGCDPLVKPVGRQACD 903
Query: 389 LEECAAFQPSSPSPLQPQGPVKSNNIVTVTGISLC 423
L+ C P QP N ++LC
Sbjct: 904 LQPCPTEPPDDSCQDQP-----GTNCALAIKVNLC 933
Score = 32.3 bits (72), Expect = 1.9
Identities = 12/31 (38%), Positives = 19/31 (61%)
Query: 338 RNTETWGLWQPWSQCSATCGDGVRERRRVCL 368
+N L Q W +C+ TCG GV++R +C+
Sbjct: 792 KNCPAHWLAQDWERCNTTCGRGVKKRLVLCM 822
>gi|41281450 ADAMTS-like 2 precursor [Homo sapiens]
Length = 951
Score = 48.1 bits (113), Expect = 3e-05
Identities = 21/56 (37%), Positives = 27/56 (48%), Gaps = 6/56 (10%)
Query: 343 WGLWQPWSQCSATCGDGVRERRRVCL------TSFPSSPVCPGMSLEASLCSLEEC 392
WG W W+ CS +CG GV + R CL P + C G S LC ++EC
Sbjct: 50 WGEWTKWTACSRSCGGGVTSQERHCLQQRRKSVPGPGNRTCTGTSKRYQLCRVQEC 105
Score = 36.2 bits (82), Expect = 0.13
Identities = 26/95 (27%), Positives = 34/95 (35%), Gaps = 8/95 (8%)
Query: 331 EECMLIQRNTETWGLWQPWSQCSATCGDGVRERRRVCLTSFPSSPVCPGM--SLEASLCS 388
EE +R W PWS+C+ TCG GVR R C C + + C
Sbjct: 845 EESTCFERPCFKW-YTSPWSECTKTCGVGVRMRDVKCYQGTDIVRGCDPLVKPVGRQACD 903
Query: 389 LEECAAFQPSSPSPLQPQGPVKSNNIVTVTGISLC 423
L+ C P QP N ++LC
Sbjct: 904 LQPCPTEPPDDSCQDQP-----GTNCALAIKVNLC 933
Score = 32.3 bits (72), Expect = 1.9
Identities = 12/31 (38%), Positives = 19/31 (61%)
Query: 338 RNTETWGLWQPWSQCSATCGDGVRERRRVCL 368
+N L Q W +C+ TCG GV++R +C+
Sbjct: 792 KNCPAHWLAQDWERCNTTCGRGVKKRLVLCM 822
>gi|4505737 complement factor properdin precursor [Homo sapiens]
Length = 469
Score = 48.1 bits (113), Expect = 3e-05
Identities = 20/50 (40%), Positives = 24/50 (48%), Gaps = 1/50 (2%)
Query: 343 WGLWQPWSQCSATCGDGVRERRRVCLTSFPS-SPVCPGMSLEASLCSLEE 391
W W PW CS TC G R RRR C P CPG + E+ C ++
Sbjct: 139 WSGWGPWEPCSVTCSKGTRTRRRACNHPAPKCGGHCPGQAQESEACDTQQ 188
Score = 41.6 bits (96), Expect = 0.003
Identities = 26/76 (34%), Positives = 33/76 (43%), Gaps = 15/76 (19%)
Query: 343 WGLWQPWSQCSATCGDGVRE----RRRVCLTSFPS----SPVCPGMSLEASLCS-LEEC- 392
W W PW+ CSA+C G E R R C PS CPG++ E C+ L C
Sbjct: 196 WATWGPWTPCSASCHGGPHEPKETRSRKCSAPEPSQKPPGKPCPGLAYEQRRCTGLPPCP 255
Query: 393 -----AAFQPSSPSPL 403
+ P SP P+
Sbjct: 256 VAGGWGPWGPVSPCPV 271
Score = 38.9 bits (89), Expect = 0.020
Identities = 18/53 (33%), Positives = 26/53 (49%), Gaps = 3/53 (5%)
Query: 343 WGLWQPWSQCSATCGDGVRERRRVCL--TSFPSSPVCPG-MSLEASLCSLEEC 392
W LW W+ CS TC +G + R R C+ S V PG + + C ++C
Sbjct: 80 WSLWSTWAPCSVTCSEGSQLRYRRCVGWNGQCSGKVAPGTLEWQLQACEDQQC 132
Score = 37.4 bits (85), Expect = 0.059
Identities = 17/48 (35%), Positives = 21/48 (43%), Gaps = 2/48 (4%)
Query: 343 WGLWQPWSQCSATCGDGVRERRRVCLTSFP--SSPVCPGMSLEASLCS 388
WG W P S C TCG G +R C P P C G + +C+
Sbjct: 260 WGPWGPVSPCPVTCGLGQTMEQRTCNHPVPQHGGPFCAGDATRTHICN 307
Score = 31.2 bits (69), Expect = 4.3
Identities = 12/35 (34%), Positives = 16/35 (45%), Gaps = 1/35 (2%)
Query: 342 TWGLWQPWSQCSATCG-DGVRERRRVCLTSFPSSP 375
+W W W C CG + R R+R+C P P
Sbjct: 381 SWSEWSTWGLCMPPCGPNPTRARQRLCTPLLPKYP 415
>gi|223671861 complement factor properdin precursor [Homo sapiens]
Length = 469
Score = 48.1 bits (113), Expect = 3e-05
Identities = 20/50 (40%), Positives = 24/50 (48%), Gaps = 1/50 (2%)
Query: 343 WGLWQPWSQCSATCGDGVRERRRVCLTSFPS-SPVCPGMSLEASLCSLEE 391
W W PW CS TC G R RRR C P CPG + E+ C ++
Sbjct: 139 WSGWGPWEPCSVTCSKGTRTRRRACNHPAPKCGGHCPGQAQESEACDTQQ 188
Score = 41.6 bits (96), Expect = 0.003
Identities = 26/76 (34%), Positives = 33/76 (43%), Gaps = 15/76 (19%)
Query: 343 WGLWQPWSQCSATCGDGVRE----RRRVCLTSFPS----SPVCPGMSLEASLCS-LEEC- 392
W W PW+ CSA+C G E R R C PS CPG++ E C+ L C
Sbjct: 196 WATWGPWTPCSASCHGGPHEPKETRSRKCSAPEPSQKPPGKPCPGLAYEQRRCTGLPPCP 255
Query: 393 -----AAFQPSSPSPL 403
+ P SP P+
Sbjct: 256 VAGGWGPWGPVSPCPV 271
Score = 38.9 bits (89), Expect = 0.020
Identities = 18/53 (33%), Positives = 26/53 (49%), Gaps = 3/53 (5%)
Query: 343 WGLWQPWSQCSATCGDGVRERRRVCL--TSFPSSPVCPG-MSLEASLCSLEEC 392
W LW W+ CS TC +G + R R C+ S V PG + + C ++C
Sbjct: 80 WSLWSTWAPCSVTCSEGSQLRYRRCVGWNGQCSGKVAPGTLEWQLQACEDQQC 132
Score = 37.4 bits (85), Expect = 0.059
Identities = 17/48 (35%), Positives = 21/48 (43%), Gaps = 2/48 (4%)
Query: 343 WGLWQPWSQCSATCGDGVRERRRVCLTSFP--SSPVCPGMSLEASLCS 388
WG W P S C TCG G +R C P P C G + +C+
Sbjct: 260 WGPWGPVSPCPVTCGLGQTMEQRTCNHPVPQHGGPFCAGDATRTHICN 307
Score = 31.2 bits (69), Expect = 4.3
Identities = 12/35 (34%), Positives = 16/35 (45%), Gaps = 1/35 (2%)
Query: 342 TWGLWQPWSQCSATCG-DGVRERRRVCLTSFPSSP 375
+W W W C CG + R R+R+C P P
Sbjct: 381 SWSEWSTWGLCMPPCGPNPTRARQRLCTPLLPKYP 415
>gi|4502359 brain-specific angiogenesis inhibitor 3 [Homo sapiens]
Length = 1522
Score = 47.8 bits (112), Expect = 4e-05
Identities = 20/52 (38%), Positives = 25/52 (48%)
Query: 343 WGLWQPWSQCSATCGDGVRERRRVCLTSFPSSPVCPGMSLEASLCSLEECAA 394
W W WSQCS TC +G ++R R C + C G E+ C EC A
Sbjct: 403 WQEWSSWSQCSVTCSNGTQQRSRQCTAAAHGGSECRGPWAESRECYNPECTA 454
Score = 43.1 bits (100), Expect = 0.001
Identities = 19/50 (38%), Positives = 21/50 (42%)
Query: 343 WGLWQPWSQCSATCGDGVRERRRVCLTSFPSSPVCPGMSLEASLCSLEEC 392
W W PWS CS TCG G R R R C C G C++ C
Sbjct: 348 WEEWSPWSLCSFTCGRGQRTRTRSCTPPQYGGRPCEGPETHHKPCNIALC 397
Score = 41.2 bits (95), Expect = 0.004
Identities = 18/52 (34%), Positives = 22/52 (42%)
Query: 343 WGLWQPWSQCSATCGDGVRERRRVCLTSFPSSPVCPGMSLEASLCSLEECAA 394
W W WS CS +C G R R C + + C G E CS + C A
Sbjct: 458 WNQWGHWSGCSKSCDGGWERRIRTCQGAVITGQQCEGTGEEVRRCSEQRCPA 509
Score = 40.0 bits (92), Expect = 0.009
Identities = 17/43 (39%), Positives = 23/43 (53%), Gaps = 2/43 (4%)
Query: 346 WQPWSQCSATCGDGVRERRRVCLTSFPSSPVCPGMSLEASLCS 388
W WS CS TCG G + R R C++ P C G E+ +C+
Sbjct: 297 WSQWSTCSVTCGQGSQVRTRTCVS--PYGTHCSGPLRESRVCN 337
>gi|21265043 ADAM metallopeptidase with thrombospondin type 1 motif,
13 isoform 3 preproprotein [Homo sapiens]
Length = 1340
Score = 47.0 bits (110), Expect = 7e-05
Identities = 22/56 (39%), Positives = 28/56 (50%), Gaps = 2/56 (3%)
Query: 343 WGLWQPWSQCSATCGDGVRERRRVCLTSFPS--SPVCPGMSLEASLCSLEECAAFQ 396
W W P S CS +CG GV RRR C P+ C G L+A +C+ + C Q
Sbjct: 356 WSSWGPRSPCSRSCGGGVVTRRRQCNNPRPAFGGRACVGADLQAEMCNTQACEKTQ 411
Score = 40.8 bits (94), Expect = 0.005
Identities = 26/84 (30%), Positives = 37/84 (44%), Gaps = 2/84 (2%)
Query: 293 SLPLGERRTIFNCTLFDMGKNKYCFDFGISSRSHFSAKEECMLIQRNTETWGLWQPWSQC 352
S LG R C D G++ + ++ A C LI T W + W +C
Sbjct: 996 SCGLGTARRSVACVQLDQGQDVEVDEAACAALVRPEASVPC-LIADCTYRWHVGT-WMEC 1053
Query: 353 SATCGDGVRERRRVCLTSFPSSPV 376
S +CGDG++ RR CL +PV
Sbjct: 1054 SVSCGDGIQRRRDTCLGPQAQAPV 1077
>gi|73695936 ADAM metallopeptidase with thrombospondin type 1 motif,
13 isoform 2 preproprotein [Homo sapiens]
Length = 1371
Score = 47.0 bits (110), Expect = 7e-05
Identities = 22/56 (39%), Positives = 28/56 (50%), Gaps = 2/56 (3%)
Query: 343 WGLWQPWSQCSATCGDGVRERRRVCLTSFPS--SPVCPGMSLEASLCSLEECAAFQ 396
W W P S CS +CG GV RRR C P+ C G L+A +C+ + C Q
Sbjct: 387 WSSWGPRSPCSRSCGGGVVTRRRQCNNPRPAFGGRACVGADLQAEMCNTQACEKTQ 442
Score = 40.8 bits (94), Expect = 0.005
Identities = 26/84 (30%), Positives = 37/84 (44%), Gaps = 2/84 (2%)
Query: 293 SLPLGERRTIFNCTLFDMGKNKYCFDFGISSRSHFSAKEECMLIQRNTETWGLWQPWSQC 352
S LG R C D G++ + ++ A C LI T W + W +C
Sbjct: 1027 SCGLGTARRSVACVQLDQGQDVEVDEAACAALVRPEASVPC-LIADCTYRWHVGT-WMEC 1084
Query: 353 SATCGDGVRERRRVCLTSFPSSPV 376
S +CGDG++ RR CL +PV
Sbjct: 1085 SVSCGDGIQRRRDTCLGPQAQAPV 1108
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.132 0.402
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 37,353,790
Number of Sequences: 37866
Number of extensions: 1944918
Number of successful extensions: 8864
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 67
Number of HSP's successfully gapped in prelim test: 82
Number of HSP's that attempted gapping in prelim test: 8370
Number of HSP's gapped (non-prelim): 540
length of query: 852
length of database: 18,247,518
effective HSP length: 111
effective length of query: 741
effective length of database: 14,044,392
effective search space: 10406894472
effective search space used: 10406894472
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.