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Search of human proteins with 8923720
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|8923720 zinc finger, C4H2 domain containing [Homo sapiens]
(224 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|8923720 zinc finger, C4H2 domain containing [Homo sapiens] 449 e-127
gi|33356174 pinin, desmosome associated protein [Homo sapiens] 49 3e-06
gi|114155142 nuclear pore complex-associated protein TPR [Homo s... 46 2e-05
gi|71061468 centromere protein E [Homo sapiens] 46 3e-05
gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo sap... 45 4e-05
gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens] 45 4e-05
gi|38570058 hypothetical protein LOC80129 [Homo sapiens] 45 7e-05
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s... 44 9e-05
gi|29171755 PTPRF interacting protein alpha 2 [Homo sapiens] 44 1e-04
gi|42740899 CTAGE family, member 5 isoform 3 [Homo sapiens] 43 2e-04
gi|42740897 CTAGE family, member 5 isoform 1 [Homo sapiens] 43 2e-04
gi|42740901 CTAGE family, member 5 isoform 4 [Homo sapiens] 43 2e-04
gi|42740905 CTAGE family, member 5 isoform 2 [Homo sapiens] 43 2e-04
gi|5803145 ralA binding protein 1 [Homo sapiens] 42 3e-04
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 42 3e-04
gi|31542634 filamin A interacting protein 1 [Homo sapiens] 42 3e-04
gi|225579095 S-phase cyclin A-associated protein in the ER isofo... 42 4e-04
gi|225579092 S-phase cyclin A-associated protein in the ER isofo... 42 4e-04
gi|14165274 golgi-associated microtubule-binding protein HOOK3 [... 42 4e-04
gi|239745299 PREDICTED: hypothetical protein [Homo sapiens] 42 6e-04
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 42 6e-04
gi|21735548 centrosomal protein 2 [Homo sapiens] 41 7e-04
gi|156104908 myosin heavy chain 6 [Homo sapiens] 41 7e-04
gi|229577185 epidermal growth factor receptor pathway substrate ... 41 0.001
gi|4503593 epidermal growth factor receptor pathway substrate 15... 41 0.001
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 41 0.001
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo... 41 0.001
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo... 41 0.001
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 40 0.001
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo... 40 0.001
>gi|8923720 zinc finger, C4H2 domain containing [Homo sapiens]
Length = 224
Score = 449 bits (1155), Expect = e-127
Identities = 224/224 (100%), Positives = 224/224 (100%)
Query: 1 MADEQEIMCKLESIKEIRNKTLQMEKIKARLKAEFEALESEERHLKEYKQEMDLLLQEKM 60
MADEQEIMCKLESIKEIRNKTLQMEKIKARLKAEFEALESEERHLKEYKQEMDLLLQEKM
Sbjct: 1 MADEQEIMCKLESIKEIRNKTLQMEKIKARLKAEFEALESEERHLKEYKQEMDLLLQEKM 60
Query: 61 AHVEELRLIHADINVMENTIKQSENDLNKLLESTRRLHDEYKPLKEHVDALRMTLGLQRL 120
AHVEELRLIHADINVMENTIKQSENDLNKLLESTRRLHDEYKPLKEHVDALRMTLGLQRL
Sbjct: 61 AHVEELRLIHADINVMENTIKQSENDLNKLLESTRRLHDEYKPLKEHVDALRMTLGLQRL 120
Query: 121 PDLCEEEEKLSLDYFEKQKAEWQTEPQEPPIPESLAAAAAAAQQLQVARKQDTRQTATFR 180
PDLCEEEEKLSLDYFEKQKAEWQTEPQEPPIPESLAAAAAAAQQLQVARKQDTRQTATFR
Sbjct: 121 PDLCEEEEKLSLDYFEKQKAEWQTEPQEPPIPESLAAAAAAAQQLQVARKQDTRQTATFR 180
Query: 181 QQPPPMKACLSCHQQIHRNAPICPLCKAKSRSRNPKKPKRKQDE 224
QQPPPMKACLSCHQQIHRNAPICPLCKAKSRSRNPKKPKRKQDE
Sbjct: 181 QQPPPMKACLSCHQQIHRNAPICPLCKAKSRSRNPKKPKRKQDE 224
>gi|33356174 pinin, desmosome associated protein [Homo sapiens]
Length = 717
Score = 48.9 bits (115), Expect = 3e-06
Identities = 49/184 (26%), Positives = 84/184 (45%), Gaps = 31/184 (16%)
Query: 3 DEQEIMCKLESIKEIRNKTLQMEKIKARLKAEFEALESEERHLKEYKQEMDLLLQEKMAH 62
+E+EI ++ + + Q ++++ +++ E E ESE++ + ++ MD+L
Sbjct: 338 EEKEIAIVHSDAEKEQEEEEQKQEMEVKMEEETEVRESEKQQDSQPEEVMDVL-----EM 392
Query: 63 VEELRLIHADINVME----NTIKQSENDLNKLLESTRRLHDE-------YKPLKEHVDAL 111
VE ++ + AD VME +++ SEN+ +K LE E P KE+V AL
Sbjct: 393 VENVKHVIADQEVMETNRVESVEPSENEASKELEPEMEFEIEPDKECKSLSPGKENVSAL 452
Query: 112 RMTLGLQRLPDLCEEEEKLSLDYFEKQKAEWQTEPQEPPIPESLAAAAAAAQQLQVARKQ 171
M E EEK E++++E Q EP P P+S +Q V + Q
Sbjct: 453 DMEK---------ESEEK------EEKESEPQPEPVAQPQPQSQPQLQLQSQSQPVLQSQ 497
Query: 172 DTRQ 175
Q
Sbjct: 498 PPSQ 501
>gi|114155142 nuclear pore complex-associated protein TPR [Homo
sapiens]
Length = 2363
Score = 46.2 bits (108), Expect = 2e-05
Identities = 40/181 (22%), Positives = 80/181 (44%), Gaps = 12/181 (6%)
Query: 4 EQEIMCKLESIKEIRNKTLQMEKIKARLKAEFEALESEERHLKEYKQEMDLLLQEKMAHV 63
++++ K+ I+E Q++KI R K ++E L++++ + E + QE+ V
Sbjct: 1414 QKDLDAKIIDIQEKVKTITQVKKIGRRYKTQYEELKAQQDKVMETSAQSSGDHQEQHVSV 1473
Query: 64 EELRLIHADINVMENTIKQSENDLNKLLESTRRLHDEYKPLKEHVDALRMTLG--LQRLP 121
+E++ + +N E K E+ + L ++ E + L+E L+ L Q L
Sbjct: 1474 QEMQELKETLNQAETKSKSLESQVENLQKTLSEKETEARNLQEQTVQLQSELSRLRQDLQ 1533
Query: 122 DLCEEEEKLSLDYFEKQKAEWQTEPQEPPIPESLAAAAAAAQQLQVARKQDTRQTATFRQ 181
D +EE+L EK E +++ AA + L + Q T++ +Q
Sbjct: 1534 DRTTQEEQLRQQITEK----------EEKTRKAIVAAKSKIAHLAGVKDQLTKENEELKQ 1583
Query: 182 Q 182
+
Sbjct: 1584 R 1584
Score = 32.7 bits (73), Expect = 0.26
Identities = 37/129 (28%), Positives = 59/129 (45%), Gaps = 13/129 (10%)
Query: 12 ESIKEIRNKTLQMEKIKARLKAEFEALESEERHLKEY---KQEMDLLLQEKMAHVEELRL 68
+ I E R + Q+E ++ R + E LE E + L++ ++E + + MA EEL
Sbjct: 1207 KEIAETRFEVAQVESLRYRQRVEL--LERELQELQDSLNAEREKVQVTAKTMAQHEELMK 1264
Query: 69 IHADINVMENTIK-------QSENDLNKLLESTRRLHDEYKPLKEHVDALRMTLG-LQRL 120
+NV+ T K + E DL ++ R+L + PL+E L G LQ
Sbjct: 1265 KTETMNVVMETNKMLREEKERLEQDLQQMQAKVRKLELDILPLQEANAELSEKSGMLQAE 1324
Query: 121 PDLCEEEEK 129
L EE+ K
Sbjct: 1325 KKLLEEDVK 1333
Score = 32.3 bits (72), Expect = 0.34
Identities = 36/185 (19%), Positives = 88/185 (47%), Gaps = 26/185 (14%)
Query: 8 MCKLESIKEIRNKTL--QMEKIKARLKAEFE---------ALESEERHLKEYKQEMDLLL 56
+C+ E +++ +N+ L Q+EK+ ++ A + +L E + ++ + + +
Sbjct: 1146 VCRCEDLEK-QNRLLHDQIEKLSDKVVASVKEGVQGPLNVSLSEEGKSQEQILEILRFIR 1204
Query: 57 QEK--------MAHVEELRLIHADINVMENTIKQSENDLN---KLLESTRRLHDEYKPLK 105
+EK +A VE LR + ++E +++ ++ LN + ++ T + +++ L
Sbjct: 1205 REKEIAETRFEVAQVESLRY-RQRVELLERELQELQDSLNAEREKVQVTAKTMAQHEELM 1263
Query: 106 EHVDALRMTLGLQRLPDLCEEEEKLSLDYFEKQKAEWQTEPQEPPIPESLAAAAAAAQQL 165
+ + + + + ++ L EE+E+L D + Q + E P+ E+ A + + L
Sbjct: 1264 KKTETMNVVMETNKM--LREEKERLEQDLQQMQAKVRKLELDILPLQEANAELSEKSGML 1321
Query: 166 QVARK 170
Q +K
Sbjct: 1322 QAEKK 1326
Score = 28.5 bits (62), Expect = 4.9
Identities = 30/143 (20%), Positives = 62/143 (43%), Gaps = 30/143 (20%)
Query: 15 KEIRNKTLQMEKIKARLKAEFEALESEERHLKEYKQEMDLLLQEKMAHVEELRLIH--AD 72
K ++NK +EK A ++E + L+ K ++ ++++++H +E RL++ +
Sbjct: 19 KSVQNK---LEKFLADQQSEIDGLKGRHEKFKVESEQQYFEIEKRLSHSQE-RLVNETRE 74
Query: 73 INVMENTIKQSENDLNKLLESTRRL----------HDEYKPLKEHVDALRMTLGLQRLPD 122
+ +++ N L L E + L ++ KE ++A + D
Sbjct: 75 CQSLRLELEKLNNQLKALTEKNKELEIAQDRNIAIQSQFTRTKEELEAEKR--------D 126
Query: 123 LCEEEEKLSLDYFEKQKAEWQTE 145
L E+LS Q+ E+ TE
Sbjct: 127 LIRTNERLS------QELEYLTE 143
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 45.8 bits (107), Expect = 3e-05
Identities = 35/129 (27%), Positives = 68/129 (52%), Gaps = 27/129 (20%)
Query: 11 LESIKEIR----NKTLQMEKIKARL---KAEFEALESEERHLKEYKQEMDLLLQEK---- 59
L+++ EI K L E I++ L +A+++ L + L+ K+EM+L L+EK
Sbjct: 476 LDTLSEIEWNPATKLLNQENIESELNSLRADYDNLVLDYEQLRTEKEEMELKLKEKNDLD 535
Query: 60 --------MAHVEELRLIHADINVMENTIKQSE-------NDLNKLLESTRRLHDEYKPL 104
+E++LIH +I+ ++N +K +E N+L+ +E R D+ K L
Sbjct: 536 EFEALERKTKKDQEMQLIH-EISNLKNLVKHAEVYNQDLENELSSKVELLREKEDQIKKL 594
Query: 105 KEHVDALRM 113
+E++D+ ++
Sbjct: 595 QEYIDSQKL 603
Score = 38.9 bits (89), Expect = 0.004
Identities = 39/158 (24%), Positives = 75/158 (47%), Gaps = 19/158 (12%)
Query: 2 ADEQEIMCKLESIKEIRNKTLQMEKIKARLKAEFEALESEE-------RHLKEYKQEMDL 54
A+E +++ + + E + K +ME++K ++K + L E + L E +EM
Sbjct: 1827 ANEHQLITLKKDVNETQKKVSEMEQLKKQIKDQSLTLSKLEIENLNLAQKLHENLEEMKS 1886
Query: 55 LLQEK--MAHVEE-LRLIHADINVMENTIKQSENDLNKLLESTRRLHDEYKPLKEHVDAL 111
+++E+ + VEE L+L + K + ++ + L++ R L E+ KE VD L
Sbjct: 1887 VMKERDNLRRVEETLKLERDQLKESLQETKARDLEIQQELKTARMLSKEH---KETVDKL 1943
Query: 112 RMTLGLQRL------PDLCEEEEKLSLDYFEKQKAEWQ 143
R + + + DL + +++L E QK E Q
Sbjct: 1944 REKISEKTIQISDIQKDLDKSKDELQKKIQELQKKELQ 1981
Score = 37.0 bits (84), Expect = 0.014
Identities = 36/151 (23%), Positives = 75/151 (49%), Gaps = 30/151 (19%)
Query: 4 EQEIMCKLESIKEIRNKTLQMEKIKARLKAEFEAL---ESE----ERHLKEYKQEMDLLL 56
E+E ++ I E++ K ++++ K KA+ AL ES+ L+E ++E+ +++
Sbjct: 1530 EKEEQFNIKQISEVQEKVNELKQFKEHRKAKDSALQSIESKMLELTNRLQESQEEIQIMI 1589
Query: 57 QEKMAHVEELRLIHADINVMENTIKQSENDL-NKLLESTRRLHDEYKPLKEHVDALRMTL 115
+EK EE++ + + + + +K++ ++ K+ ES + EY+ LK MT
Sbjct: 1590 KEK----EEMKRVQEALQIERDQLKENTKEIVAKMKESQEK---EYQFLK-------MTA 1635
Query: 116 GLQRLPDLCE--------EEEKLSLDYFEKQ 138
+ +CE E +KL+L+ E +
Sbjct: 1636 VNETQEKMCEIEHLKEQFETQKLNLENIETE 1666
Score = 35.0 bits (79), Expect = 0.052
Identities = 32/152 (21%), Positives = 66/152 (43%), Gaps = 8/152 (5%)
Query: 4 EQEIMCKLESIKEIRNKTLQMEKIKARLKAEFEALESEERHLKEYKQEMDLLLQEKMAHV 63
EQ+ LE + + + + + K + + AL++E + + QE +QE++ +
Sbjct: 830 EQKYKMVLEENERMNQEIVNLSKEAQKFDSSLGALKTELSYKTQELQEKTREVQERLNEM 889
Query: 64 EELRLIHADINVMENTIKQSENDLNKLLESTRRLHDEYKPLKEHVDALRMTLGLQRLPDL 123
E+L+ + ++T++ E + + E ++ +E K L + D L+ Q L
Sbjct: 890 EQLK---EQLENRDSTLQTVEREKTLITEKLQQTLEEVKTLTQEKDDLK-----QLQESL 941
Query: 124 CEEEEKLSLDYFEKQKAEWQTEPQEPPIPESL 155
E ++L D + T+ Q ESL
Sbjct: 942 QIERDQLKSDIHDTVNMNIDTQEQLRNALESL 973
Score = 33.9 bits (76), Expect = 0.12
Identities = 46/225 (20%), Positives = 98/225 (43%), Gaps = 28/225 (12%)
Query: 12 ESIKEIRNKTLQMEKIKARLKAEFEALESEERHLKEYKQEMDLL-LQEKMAHVEELRLIH 70
E+ +E+++ T + + +K K+ E+E HL+ Y +E++ LQ K EEL++ H
Sbjct: 1190 ENYEEVKSITKERKVLKELQKS----FETERDHLRGYIREIEATGLQTK----EELKIAH 1241
Query: 71 ADINVMENTI---KQSENDLNKLLESTRRLHDEYKPLKEHVDALRMTLGLQRLPDLCEEE 127
+ + TI ++S ++ + +T+ L + L+E + L L LP++ E
Sbjct: 1242 IHLKEHQETIDELRRSVSEKTAQIINTQDLEKSHTKLQEEIPVLHEEQEL--LPNVKEVS 1299
Query: 128 EKLSLDYFEKQKAEWQTEPQEPPIPESLAAAAAAAQQLQVARK-----QDTRQTATFRQQ 182
E ++ E + ++ +S A ++L++ K ++ + R
Sbjct: 1300 ET------QETMNELELLTEQSTTKDSTTLARIEMERLRLNEKFQESQEEIKSLTKERDN 1353
Query: 183 PPPMKACLSC-HQQI--HRNAPICPLCKAKSRSRNPKKPKRKQDE 224
+K L H Q+ H + + +++S+ K K +E
Sbjct: 1354 LKTIKEALEVKHDQLKEHIRETLAKIQESQSKQEQSLNMKEKDNE 1398
Score = 33.1 bits (74), Expect = 0.20
Identities = 41/193 (21%), Positives = 78/193 (40%), Gaps = 20/193 (10%)
Query: 4 EQEIMCKLESIKEIRNKTLQMEKIKARLKAEFEALESEERHLKEY-------------KQ 50
E E + E +E + + + K + LK EALE + LKE+ KQ
Sbjct: 1327 EMERLRLNEKFQESQEEIKSLTKERDNLKTIKEALEVKHDQLKEHIRETLAKIQESQSKQ 1386
Query: 51 EMDLLLQEKMAHVEELRLIHADINVMENTIKQSENDLNKLLESTRRLHDEYKPLKEHVDA 110
E L ++EK ++ ++ + + E ++ L + + HDE K + + D
Sbjct: 1387 EQSLNMKEKDNETTKIVSEMEQFKPKDSALLRIEIEMLGLSKRLQESHDEMKSVAKEKD- 1445
Query: 111 LRMTLGLQRLPDLCE-EEEKLSLDYFEKQKAEWQTEPQEPPIPESLAAAAAAAQQLQVAR 169
LQRL ++ + E ++L + E +TE + L +L+V
Sbjct: 1446 -----DLQRLQEVLQSESDQLKENIKEIVAKHLETEEELKVAHCCLKEQEETINELRVNL 1500
Query: 170 KQDTRQTATFRQQ 182
+ + +T ++Q
Sbjct: 1501 SEKETEISTIQKQ 1513
Score = 32.0 bits (71), Expect = 0.44
Identities = 39/198 (19%), Positives = 82/198 (41%), Gaps = 14/198 (7%)
Query: 4 EQEIMCKLESIKEIRNKTLQMEKIKARLKAEFEALESEERHLKEYKQEMDLLLQEKMAHV 63
E+ + + + +KE +T+ + K E L+ HLKE+++ +D L
Sbjct: 1695 EETLKVERDQLKENLRETITRDLEKQ------EELKIVHMHLKEHQETIDKLRGIVSEKT 1748
Query: 64 EELRLIHADINVMENTIKQSENDLNKLLESTRRLHDEYKPLKEHVDALR--MTLGLQRLP 121
E+ + D+ + +K + K+ E R H K +E +D LR ++ +L
Sbjct: 1749 NEISNMQKDLEHSNDALKAQD---LKIQEELRIAHMHLKEQQETIDKLRGIVSEKTDKLS 1805
Query: 122 DLCEEEEKLSLDYFEKQKAEWQTEPQEPPIPESLAAAAAAAQQLQVARKQDTRQTATFRQ 181
++ ++ E + EK + E Q + + + +++ +KQ Q+ T +
Sbjct: 1806 NMQKDLENSNAKLQEKIQELKANEHQLITLKKDVNETQKKVSEMEQLKKQIKDQSLTLSK 1865
Query: 182 QPPPMKACLSCHQQIHRN 199
L+ Q++H N
Sbjct: 1866 LEIEN---LNLAQKLHEN 1880
Score = 30.8 bits (68), Expect = 0.98
Identities = 25/99 (25%), Positives = 47/99 (47%), Gaps = 7/99 (7%)
Query: 5 QEIMCKLESIKEIRNKTLQMEKIKARLKAEFEALESEERHLKEYKQ---EMDLLLQEKMA 61
++++C LE + K ++K + E EAL E L E K E++ L +E
Sbjct: 710 KDLLCNLE----LEGKITDLQKELNKEVEENEALREEVILLSELKSLPSEVERLRKEIQD 765
Query: 62 HVEELRLIHADINVMENTIKQSENDLNKLLESTRRLHDE 100
EEL +I ++ + + + + E+ + LLE + D+
Sbjct: 766 KSEELHIITSEKDKLFSEVVHKESRVQGLLEEIGKTKDD 804
Score = 30.8 bits (68), Expect = 0.98
Identities = 24/115 (20%), Positives = 52/115 (45%), Gaps = 22/115 (19%)
Query: 12 ESIKEIRNKTLQMEKIKARLKAEFEALESEERH-------LKEYKQEMDLLLQEKMAHVE 64
E +E++ + +ME++K +L+ L++ ER L++ +E+ L QEK +
Sbjct: 877 EKTREVQERLNEMEQLKEQLENRDSTLQTVEREKTLITEKLQQTLEEVKTLTQEK----D 932
Query: 65 ELRLIHADINVMENTIKQSEND-----------LNKLLESTRRLHDEYKPLKEHV 108
+L+ + + + + +K +D L LES ++ + LK +
Sbjct: 933 DLKQLQESLQIERDQLKSDIHDTVNMNIDTQEQLRNALESLKQHQETINTLKSKI 987
Score = 30.8 bits (68), Expect = 0.98
Identities = 28/121 (23%), Positives = 54/121 (44%), Gaps = 10/121 (8%)
Query: 6 EIMCKLESIKEIRNKTLQMEKIKARLKAEFEALESEERHLKEYKQEMDLLLQEKMAHVEE 65
E+ + E + + +N ++ E L + L E LKE Q++ Q+ + EE
Sbjct: 1093 ELKKQQEIVAQEKNHAIKKE---GELSRTCDRLAEVEEKLKEKSQQLQEKQQQLLNVQEE 1149
Query: 66 LRLIHADINVME---NTIKQSENDLNKL----LESTRRLHDEYKPLKEHVDALRMTLGLQ 118
+ + IN +E N +K E L + LE ++L++ Y+ +K ++ LQ
Sbjct: 1150 MSEMQKKINEIENLKNELKNKELTLEHMETERLELAQKLNENYEEVKSITKERKVLKELQ 1209
Query: 119 R 119
+
Sbjct: 1210 K 1210
Score = 29.3 bits (64), Expect = 2.8
Identities = 26/108 (24%), Positives = 52/108 (48%), Gaps = 9/108 (8%)
Query: 10 KLESIKEIRNKTLQMEKIKARLKAEFEALESEERHLK-EYKQEMDLLLQEKMAHVEELRL 68
K I E + K + + K L+ E++ +E+ LK + K+ +++ ++ + EELRL
Sbjct: 1034 KDNEIIEQQRKIFSLIQEKNELQQMLESVIAEKEQLKTDLKENIEMTIENQ----EELRL 1089
Query: 69 IHADINVMENTIKQSENDLNK----LLESTRRLHDEYKPLKEHVDALR 112
+ ++ + + Q +N K L + RL + + LKE L+
Sbjct: 1090 LGDELKKQQEIVAQEKNHAIKKEGELSRTCDRLAEVEEKLKEKSQQLQ 1137
Score = 28.9 bits (63), Expect = 3.7
Identities = 25/146 (17%), Positives = 68/146 (46%), Gaps = 5/146 (3%)
Query: 24 MEKIKARLKAEFEALESEERHLKEYKQEMDLLLQEKMAHVEELRLIHADINVMENTIKQS 83
++K++ + + + L + ++ L+ ++ +QE A+ +L + D+N + + +
Sbjct: 1790 IDKLRGIVSEKTDKLSNMQKDLENSNAKLQEKIQELKANEHQLITLKKDVNETQKKVSEM 1849
Query: 84 ENDLNKLLESTRRLHD-EYKPL----KEHVDALRMTLGLQRLPDLCEEEEKLSLDYFEKQ 138
E ++ + + L E + L K H + M ++ +L EE L L+ + +
Sbjct: 1850 EQLKKQIKDQSLTLSKLEIENLNLAQKLHENLEEMKSVMKERDNLRRVEETLKLERDQLK 1909
Query: 139 KAEWQTEPQEPPIPESLAAAAAAAQQ 164
++ +T+ ++ I + L A +++
Sbjct: 1910 ESLQETKARDLEIQQELKTARMLSKE 1935
Score = 27.7 bits (60), Expect = 8.3
Identities = 22/104 (21%), Positives = 48/104 (46%), Gaps = 17/104 (16%)
Query: 11 LESIKEIRNKTLQMEKIKARLKAEFEA-----------------LESEERHLKEYKQEMD 53
LE I+ + + ++ +IK LK E + ++ E+R L + +Q +
Sbjct: 2031 LEEIRIVAKERDELRRIKESLKMERDQFIATLREMIARDRQNHQVKPEKRLLSDGQQHLT 2090
Query: 54 LLLQEKMAHVEELRLIHADINVMENTIKQSENDLNKLLESTRRL 97
L+EK + ++EL +++++ + + DL K +E + L
Sbjct: 2091 ESLREKCSRIKELLKRYSEMDDHYECLNRLSLDLEKEIEFQKEL 2134
Score = 27.7 bits (60), Expect = 8.3
Identities = 20/75 (26%), Positives = 41/75 (54%), Gaps = 5/75 (6%)
Query: 12 ESIKEIRNKTLQMEKIKARLKAEFEALESEERHLKEYKQEMDLLLQEKMAHVEELRLIHA 71
E I++++ K ++++ K + EFE S + EY++E+ LL+E + ++ +
Sbjct: 2455 EEIEDLKMKLVKIDLEKMKNAKEFEKEISATKATVEYQKEVIRLLRENLRRSQQAQ---- 2510
Query: 72 DINVM-ENTIKQSEN 85
D +V+ E+T Q N
Sbjct: 2511 DTSVISEHTDPQPSN 2525
>gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo sapiens]
Length = 1116
Score = 45.4 bits (106), Expect = 4e-05
Identities = 35/153 (22%), Positives = 67/153 (43%), Gaps = 7/153 (4%)
Query: 5 QEIMCKLESIKEIRNKTLQMEKIKARLKAEFEALESEERHLKEYKQEMDLLLQEKMAHVE 64
QE + + K++ + MEK+K L++ L S ++ L E + + L E+ H+E
Sbjct: 862 QEESARTNAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLE 921
Query: 65 ELRLIHADINVMENTIKQSENDLNKLLESTRRLHDEYKPLKEHVDALRMTLGLQRLPDLC 124
E+ + + + + K + L +L S ++ +E LK D L +Q+L
Sbjct: 922 EVLEMKQEALLAAISEKDANIALLELSSSKKKTQEEVAALKREKDRL-----VQQLKQQT 976
Query: 125 EEEEKLSLDYFEKQ--KAEWQTEPQEPPIPESL 155
+ KL D +E K+ + P P+ +
Sbjct: 977 QNRMKLMADNYEDDHFKSSHSNQTNHKPSPDQI 1009
Score = 36.6 bits (83), Expect = 0.018
Identities = 30/126 (23%), Positives = 58/126 (46%), Gaps = 7/126 (5%)
Query: 19 NKTLQMEKIKARLKAEFEALESEERHLKEYKQEMDLLLQEKMAHVEELRL----IHADIN 74
N L E+ + +K + E S + +K +++ L K A EEL+ + A+I
Sbjct: 411 NGALSTEEREEEMK-QMEVYRSHSKFMKNKVEQLKEELSSKEAQWEELKKKAAGLQAEIG 469
Query: 75 VMENTIKQSENDLNKLLESTRRLHDEYKPLKEHVDALR--MTLGLQRLPDLCEEEEKLSL 132
++ + + + +L L L +++ K+H++ L+ +T QR L E + L L
Sbjct: 470 QVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRL 529
Query: 133 DYFEKQ 138
EK+
Sbjct: 530 RLEEKE 535
Score = 32.7 bits (73), Expect = 0.26
Identities = 25/101 (24%), Positives = 46/101 (45%), Gaps = 3/101 (2%)
Query: 15 KEIRNKTLQMEKIKARLKAEFEALESEERHLKEYKQEMDLLLQEKMAHVEELRLIHADIN 74
K ++NK Q+++ + +A++E L+ + L+ E+ + QE EL + +
Sbjct: 434 KFMKNKVEQLKEELSSKEAQWEELKKKAAGLQA---EIGQVKQELSRKDTELLALQTKLE 490
Query: 75 VMENTIKQSENDLNKLLESTRRLHDEYKPLKEHVDALRMTL 115
+ N S+ + L ES L+ VDALR+ L
Sbjct: 491 TLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRL 531
Score = 32.3 bits (72), Expect = 0.34
Identities = 46/180 (25%), Positives = 80/180 (44%), Gaps = 27/180 (15%)
Query: 10 KLESIKE-IRNKTLQMEKIKARLKAEF--------------EALESEERHLKEYKQEMDL 54
K+E+++E +R+K QM +K R+K+ EAL +ER ++ K++ D
Sbjct: 579 KIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDR 638
Query: 55 LLQEKMAHVEELRLIHADINVMENTIKQSENDLNKLLESTRRLHDEYKPLKEHVDALRMT 114
+EK EE+ D+ ++ + + DL+ E L D LKEH +L +
Sbjct: 639 DEREKQ---EEIDNYKKDLKDLKEKVSLLQGDLS---EKEASLLD----LKEHASSLASS 688
Query: 115 LGLQRLPDLCEEEEKLSLDYFEKQKAEWQTEPQEPPIPESLAAAAAAAQQLQVARKQDTR 174
GL++ L E L E K E Q + E+ A+ + ++Q ++ TR
Sbjct: 689 -GLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEA-RASPEMSDRIQHLEREITR 746
>gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens]
Length = 1088
Score = 45.4 bits (106), Expect = 4e-05
Identities = 35/153 (22%), Positives = 67/153 (43%), Gaps = 7/153 (4%)
Query: 5 QEIMCKLESIKEIRNKTLQMEKIKARLKAEFEALESEERHLKEYKQEMDLLLQEKMAHVE 64
QE + + K++ + MEK+K L++ L S ++ L E + + L E+ H+E
Sbjct: 834 QEESARTNAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLE 893
Query: 65 ELRLIHADINVMENTIKQSENDLNKLLESTRRLHDEYKPLKEHVDALRMTLGLQRLPDLC 124
E+ + + + + K + L +L S ++ +E LK D L +Q+L
Sbjct: 894 EVLEMKQEALLAAISEKDANIALLELSSSKKKTQEEVAALKREKDRL-----VQQLKQQT 948
Query: 125 EEEEKLSLDYFEKQ--KAEWQTEPQEPPIPESL 155
+ KL D +E K+ + P P+ +
Sbjct: 949 QNRMKLMADNYEDDHFKSSHSNQTNHKPSPDQI 981
Score = 32.3 bits (72), Expect = 0.34
Identities = 46/180 (25%), Positives = 80/180 (44%), Gaps = 27/180 (15%)
Query: 10 KLESIKE-IRNKTLQMEKIKARLKAEF--------------EALESEERHLKEYKQEMDL 54
K+E+++E +R+K QM +K R+K+ EAL +ER ++ K++ D
Sbjct: 551 KIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDR 610
Query: 55 LLQEKMAHVEELRLIHADINVMENTIKQSENDLNKLLESTRRLHDEYKPLKEHVDALRMT 114
+EK EE+ D+ ++ + + DL+ E L D LKEH +L +
Sbjct: 611 DEREKQ---EEIDNYKKDLKDLKEKVSLLQGDLS---EKEASLLD----LKEHASSLASS 660
Query: 115 LGLQRLPDLCEEEEKLSLDYFEKQKAEWQTEPQEPPIPESLAAAAAAAQQLQVARKQDTR 174
GL++ L E L E K E Q + E+ A+ + ++Q ++ TR
Sbjct: 661 -GLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEA-RASPEMSDRIQHLEREITR 718
Score = 31.2 bits (69), Expect = 0.75
Identities = 21/82 (25%), Positives = 33/82 (40%)
Query: 34 EFEALESEERHLKEYKQEMDLLLQEKMAHVEELRLIHADINVMENTIKQSENDLNKLLES 93
E + +E H K K ++ + QE EL + + + N S+ + L ES
Sbjct: 422 EMKQMEVYRSHSKFMKNKIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKES 481
Query: 94 TRRLHDEYKPLKEHVDALRMTL 115
L+ VDALR+ L
Sbjct: 482 LTAKEQRAAILQTEVDALRLRL 503
>gi|38570058 hypothetical protein LOC80129 [Homo sapiens]
Length = 715
Score = 44.7 bits (104), Expect = 7e-05
Identities = 40/137 (29%), Positives = 68/137 (49%), Gaps = 11/137 (8%)
Query: 6 EIMCKLESIKEIRNKTLQMEKIKARLKAEFEALESEERHLKEYKQEMDLLLQEKMAH--- 62
E + +LES I NKT+ ++ +LK + E LES+E H+ +Q++ L +EK A
Sbjct: 466 EQLVRLESNAVIENKTIA-HNLQRKLKTQKERLESKELHMSLLRQKIAQLEEEKQARTAL 524
Query: 63 VEELRLIHADINVMENTIKQSENDLNKLLESTRRLHDEYKPLKEHVDALRMTLGLQRLPD 122
V E H I ++ +++ + +LN + R LH E K + L++ L++
Sbjct: 525 VVERDNAHLTIRNLQKKVERLQKELN----TCRDLHTELKAKLADTNELKIKT-LEQTKA 579
Query: 123 LCEEEEKLSLDYFEKQK 139
+ E+ S D EK K
Sbjct: 580 I--EDLNKSRDQLEKMK 594
Score = 30.8 bits (68), Expect = 0.98
Identities = 31/125 (24%), Positives = 47/125 (37%), Gaps = 18/125 (14%)
Query: 6 EIMCKLESIKEIRNKTLQMEKIKARLKAEFEALES----EERHLKEYKQEMDLLLQEKMA 61
E+ KL E++ KTL+ K L + LE E+ L K E+D E
Sbjct: 558 ELKAKLADTNELKIKTLEQTKAIEDLNKSRDQLEKMKEKAEKKLMSVKSELDTTEHEAKE 617
Query: 62 HVEELRLIHADINVMENTIKQSENDLNKLLESTRRLHDEYKPLKEHVDALRMTLGLQ--- 118
+ E R N I+ +++ L +S K L + + + LGL
Sbjct: 618 NKERAR----------NMIEVVTSEMKTLKKSLEEAEKREKQLADFREVVSQMLGLNVTS 667
Query: 119 -RLPD 122
LPD
Sbjct: 668 LALPD 672
>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
sapiens]
Length = 1935
Score = 44.3 bits (103), Expect = 9e-05
Identities = 44/173 (25%), Positives = 81/173 (46%), Gaps = 22/173 (12%)
Query: 20 KTLQMEKIKARLKAEF----EALESEERHLKEYKQEMDLLLQEKMAHVEELRLIHADINV 75
K+ + EK A +K EF EALE E KE +++M LLQEK +L+L +
Sbjct: 841 KSAEREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEK----NDLQL---QVQA 893
Query: 76 MENTIKQSENDLNKLLESTRRLHDEYKPLKEHVD-----ALRMTLGLQRLPDLCEEEEK- 129
++ + +E ++L+++ +L + K + E ++ +T ++L D C E ++
Sbjct: 894 EQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRD 953
Query: 130 ---LSLDYFEKQKAEWQTEPQEPPIPESLAAAAAAAQQLQVARK--QDTRQTA 177
L L + +K + TE + + E +A +L +K Q+ Q A
Sbjct: 954 IDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQA 1006
Score = 31.6 bits (70), Expect = 0.57
Identities = 33/132 (25%), Positives = 62/132 (46%), Gaps = 15/132 (11%)
Query: 5 QEIMCKLESI-KEIRNKTLQMEKIKARLKAEFEALESEERHLKEYKQEMDLLLQEKMAHV 63
+E +LES KE R+ + ++ K+K A E HL+ +K+E L +E
Sbjct: 1461 EESQSELESSQKEARSLSTELFKLK-------NAYEESLEHLETFKRENKNLQEEISDLT 1513
Query: 64 EELRLIHADINVMENTIKQSENDLNKLLESTRRL-----HDEYKPLKEHVDALRMTLGLQ 118
E+L I+ +E KQ E + +L + H+E K L+ ++ ++ ++
Sbjct: 1514 EQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIE 1573
Query: 119 RLPDLCEEEEKL 130
R L E++E++
Sbjct: 1574 R--KLAEKDEEM 1583
>gi|29171755 PTPRF interacting protein alpha 2 [Homo sapiens]
Length = 1257
Score = 43.5 bits (101), Expect = 1e-04
Identities = 29/109 (26%), Positives = 53/109 (48%), Gaps = 2/109 (1%)
Query: 5 QEIMCKLESIKEIRNKTLQMEKIKARLKAEFEALESE--ERHLKEYKQEMDLLLQEKMAH 62
+E M LE E +N+ LQ + + ++ E S+ +R L E + + L L+E+MA
Sbjct: 431 EERMRHLEGQLEEKNQELQRARQREKMNEEHNKRLSDTVDRLLTESNERLQLHLKERMAA 490
Query: 63 VEELRLIHADINVMENTIKQSENDLNKLLESTRRLHDEYKPLKEHVDAL 111
+EE ++ + +++S +D +L E +L E LK +L
Sbjct: 491 LEEKNVLIQESETFRKNLEESLHDKERLAEEIEKLRSELDQLKMRTGSL 539
Score = 30.0 bits (66), Expect = 1.7
Identities = 29/127 (22%), Positives = 64/127 (50%), Gaps = 13/127 (10%)
Query: 1 MADEQEIMCKLESIKEIRNKTLQMEKIKARLKAEFEALESEERHLKEYKQEMDLLLQEKM 60
++ E E++ L+S+ E +K L EK++ RL+ E + + E L QE+ + L+E+
Sbjct: 167 VSSEVEVLKALKSLFE-HHKALD-EKVRERLRVSLERVSALEEELAAANQEI-VALREQN 223
Query: 61 AHVEELRLIHADINVMENTIKQSENDLNKLLESTRRLHDEYKPLKEHVDALRMTLGLQRL 120
H++ M ++ +E++ + +E +++H E + +D+ T + L
Sbjct: 224 VHIQ---------RKMASSEGSTESEHLEGMEPGQKVH-EKRLSNGSIDSTDETSQIVEL 273
Query: 121 PDLCEEE 127
+L E++
Sbjct: 274 QELLEKQ 280
>gi|42740899 CTAGE family, member 5 isoform 3 [Homo sapiens]
Length = 761
Score = 43.1 bits (100), Expect = 2e-04
Identities = 28/108 (25%), Positives = 53/108 (49%), Gaps = 10/108 (9%)
Query: 4 EQEIMCKLESIKEIRNKTLQMEKIKARLKAEFEALESEERHLKEYKQEMDLLLQEKMAHV 63
E EI+C + +KE ++K + +++ A + ++LE E + LK E + + +
Sbjct: 142 EDEILCLEKELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTFKIFQMNE 201
Query: 64 EELRLIHADINVMENTIKQSENDLNKLLESTRRLHDEYKPLKEHVDAL 111
E L++ IK + N+ ++L ES ++L E + KE V L
Sbjct: 202 ERLKI----------AIKDALNENSQLQESQKQLLQEAEVWKEQVSEL 239
Score = 32.7 bits (73), Expect = 0.26
Identities = 29/123 (23%), Positives = 55/123 (44%), Gaps = 7/123 (5%)
Query: 29 ARLKAEFEALESEERHLKEYKQEMDLLLQEKMAHVEELRLIHADINVMENTIKQSEND-L 87
A+L A + LE E + E+D +E H++ L+ A + ENT ++EN L
Sbjct: 320 AKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQ-SENTHFENENQKL 378
Query: 88 NKLLESTRRLHDEYKPLKEHVDALRMTLGLQRLPDLCEEEEKLS-----LDYFEKQKAEW 142
+ L+ L+ E + + L++ L + +EK+S L+ + K+ +
Sbjct: 379 QQKLKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHATEELETYRKRAKDL 438
Query: 143 QTE 145
+ E
Sbjct: 439 EEE 441
>gi|42740897 CTAGE family, member 5 isoform 1 [Homo sapiens]
Length = 804
Score = 43.1 bits (100), Expect = 2e-04
Identities = 28/108 (25%), Positives = 53/108 (49%), Gaps = 10/108 (9%)
Query: 4 EQEIMCKLESIKEIRNKTLQMEKIKARLKAEFEALESEERHLKEYKQEMDLLLQEKMAHV 63
E EI+C + +KE ++K + +++ A + ++LE E + LK E + + +
Sbjct: 142 EDEILCLEKELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTFKIFQMNE 201
Query: 64 EELRLIHADINVMENTIKQSENDLNKLLESTRRLHDEYKPLKEHVDAL 111
E L++ IK + N+ ++L ES ++L E + KE V L
Sbjct: 202 ERLKI----------AIKDALNENSQLQESQKQLLQEAEVWKEQVSEL 239
Score = 32.7 bits (73), Expect = 0.26
Identities = 29/123 (23%), Positives = 55/123 (44%), Gaps = 7/123 (5%)
Query: 29 ARLKAEFEALESEERHLKEYKQEMDLLLQEKMAHVEELRLIHADINVMENTIKQSEND-L 87
A+L A + LE E + E+D +E H++ L+ A + ENT ++EN L
Sbjct: 320 AKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQ-SENTHFENENQKL 378
Query: 88 NKLLESTRRLHDEYKPLKEHVDALRMTLGLQRLPDLCEEEEKLS-----LDYFEKQKAEW 142
+ L+ L+ E + + L++ L + +EK+S L+ + K+ +
Sbjct: 379 QQKLKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHATEELETYRKRAKDL 438
Query: 143 QTE 145
+ E
Sbjct: 439 EEE 441
>gi|42740901 CTAGE family, member 5 isoform 4 [Homo sapiens]
Length = 775
Score = 43.1 bits (100), Expect = 2e-04
Identities = 28/108 (25%), Positives = 53/108 (49%), Gaps = 10/108 (9%)
Query: 4 EQEIMCKLESIKEIRNKTLQMEKIKARLKAEFEALESEERHLKEYKQEMDLLLQEKMAHV 63
E EI+C + +KE ++K + +++ A + ++LE E + LK E + + +
Sbjct: 113 EDEILCLEKELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTFKIFQMNE 172
Query: 64 EELRLIHADINVMENTIKQSENDLNKLLESTRRLHDEYKPLKEHVDAL 111
E L++ IK + N+ ++L ES ++L E + KE V L
Sbjct: 173 ERLKI----------AIKDALNENSQLQESQKQLLQEAEVWKEQVSEL 210
Score = 32.7 bits (73), Expect = 0.26
Identities = 29/123 (23%), Positives = 55/123 (44%), Gaps = 7/123 (5%)
Query: 29 ARLKAEFEALESEERHLKEYKQEMDLLLQEKMAHVEELRLIHADINVMENTIKQSEND-L 87
A+L A + LE E + E+D +E H++ L+ A + ENT ++EN L
Sbjct: 291 AKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQ-SENTHFENENQKL 349
Query: 88 NKLLESTRRLHDEYKPLKEHVDALRMTLGLQRLPDLCEEEEKLS-----LDYFEKQKAEW 142
+ L+ L+ E + + L++ L + +EK+S L+ + K+ +
Sbjct: 350 QQKLKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHATEELETYRKRAKDL 409
Query: 143 QTE 145
+ E
Sbjct: 410 EEE 412
>gi|42740905 CTAGE family, member 5 isoform 2 [Homo sapiens]
Length = 792
Score = 43.1 bits (100), Expect = 2e-04
Identities = 28/108 (25%), Positives = 53/108 (49%), Gaps = 10/108 (9%)
Query: 4 EQEIMCKLESIKEIRNKTLQMEKIKARLKAEFEALESEERHLKEYKQEMDLLLQEKMAHV 63
E EI+C + +KE ++K + +++ A + ++LE E + LK E + + +
Sbjct: 130 EDEILCLEKELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTFKIFQMNE 189
Query: 64 EELRLIHADINVMENTIKQSENDLNKLLESTRRLHDEYKPLKEHVDAL 111
E L++ IK + N+ ++L ES ++L E + KE V L
Sbjct: 190 ERLKI----------AIKDALNENSQLQESQKQLLQEAEVWKEQVSEL 227
Score = 32.7 bits (73), Expect = 0.26
Identities = 29/123 (23%), Positives = 55/123 (44%), Gaps = 7/123 (5%)
Query: 29 ARLKAEFEALESEERHLKEYKQEMDLLLQEKMAHVEELRLIHADINVMENTIKQSEND-L 87
A+L A + LE E + E+D +E H++ L+ A + ENT ++EN L
Sbjct: 308 AKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQ-SENTHFENENQKL 366
Query: 88 NKLLESTRRLHDEYKPLKEHVDALRMTLGLQRLPDLCEEEEKLS-----LDYFEKQKAEW 142
+ L+ L+ E + + L++ L + +EK+S L+ + K+ +
Sbjct: 367 QQKLKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHATEELETYRKRAKDL 426
Query: 143 QTE 145
+ E
Sbjct: 427 EEE 429
>gi|5803145 ralA binding protein 1 [Homo sapiens]
Length = 655
Score = 42.4 bits (98), Expect = 3e-04
Identities = 39/167 (23%), Positives = 75/167 (44%), Gaps = 19/167 (11%)
Query: 1 MADEQEIMCKLESI---KEIRNKTLQMEKIKA-RLKAEFEALESEERHLKEYKQEMDLLL 56
+A E EI+ + E + ++ + + EK + RL+AE ++S ++H + +E
Sbjct: 483 LAQENEILTEQEELLAMEQFLRRQIASEKEEIERLRAEIAEIQSRQQHGRSETEEYSSES 542
Query: 57 QEKMAHVEELRLIHADINVMENTIKQSENDLNKLLESTRRLHDEYKPLKEHVDALRMTLG 116
+ + EEL++I D+ ++ N LN + +H+E +E + LR+ L
Sbjct: 543 ESESEDEEELQIILEDLQRQNEELEIKNNHLN------QAIHEE----REAIIELRVQLR 592
Query: 117 LQRLPDLCEEEEKLSLDYFEKQKAEWQTEPQEPPIPESLAAAAAAAQ 163
L ++ + K E ++ EW+ +PP L AA Q
Sbjct: 593 LLQM-----QRAKAEQQAQEDEEPEWRGGAVQPPRDGVLEPKAAKEQ 634
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 42.4 bits (98), Expect = 3e-04
Identities = 42/148 (28%), Positives = 77/148 (52%), Gaps = 14/148 (9%)
Query: 15 KEIRNKTLQMEKIKARLKAEFEALESEERHLKEYKQEMDLLLQEKMAHVE-ELRLIHADI 73
+E+ T Q++++ A+L+ + E E HLKEYK++ L L++K +E +++ + AD
Sbjct: 681 QELNKITTQLDQVTAKLQDKQEHCSQLESHLKEYKEKY-LSLEQKTEELEGQIKKLEADS 739
Query: 74 NVMENTIKQSENDLNK-------LLESTRRLHDEYKPLKEHVDALRMTLGLQRLPDLCEE 126
++ + +Q+ DL + L L + + KE V + R L LQ+ + E
Sbjct: 740 LEVKASKEQALQDLQQQRQLNTDLELRATELSKQLEMEKEIVSSTR--LDLQKKSEALES 797
Query: 127 -EEKLSLDYFEKQ--KAEWQTEPQEPPI 151
++KL+ EKQ K +++T QE I
Sbjct: 798 IKQKLTKQEEEKQILKQDFETLSQETKI 825
Score = 38.1 bits (87), Expect = 0.006
Identities = 41/171 (23%), Positives = 78/171 (45%), Gaps = 23/171 (13%)
Query: 19 NKTLQMEKIKARLKAEFEALESE----ERHLKEYKQEMDLLLQEKMAHVEELRLIHADIN 74
N TL+ E+ +LK E + L+S+ E + + + E+ QE +V+EL+ + + +N
Sbjct: 239 NMTLERERESEKLKDECKKLQSQYASSEATISQLRSELAKGPQEVAVYVQELQKLKSSVN 298
Query: 75 --------VMENTIKQSENDLNKLLESTRRLHDEYKPLKEHVDAL--RMTLGLQRLPDLC 124
+ EN +K+ E D KL E H+E K+++ A + L Q+L
Sbjct: 299 ELTQKNQTLTENLLKK-EQDYTKLEEK----HNEESVSKKNIQATLHQKDLDCQQLQSRL 353
Query: 125 EEEE----KLSLDYFEKQKAEWQTEPQEPPIPESLAAAAAAAQQLQVARKQ 171
E ++ ++ EK +A + + + + A +QLQ R++
Sbjct: 354 SASETSLHRIHVELSEKGEATQKLKEELSEVETKYQHLKAEFKQLQQQREE 404
Score = 36.6 bits (83), Expect = 0.018
Identities = 42/215 (19%), Positives = 88/215 (40%), Gaps = 13/215 (6%)
Query: 14 IKEIRNKTLQMEKIKARLKAEFEALESEERHLK-EYKQEMDLLLQEKMAHVEELRLIHAD 72
++ +++ L +E L ++ + + L + K + +LLL + A + +
Sbjct: 609 LRAAQDRVLSLETSVNELNSQLNESKEKVSQLDIQIKAKTELLLSAEAAKTAQRADLQNH 668
Query: 73 INVMENTIKQSENDLNKLLESTRRLHDEYKPLKEHVDALRMTLGLQRLPDLCEEEEKLSL 132
++ +N ++ + +LNK+ ++ + + +EH L L + E+ LSL
Sbjct: 669 LDTAQNALQDKQQELNKITTQLDQVTAKLQDKQEHCSQLESHLKEYK-------EKYLSL 721
Query: 133 DYFEKQKAEWQTEPQEPPIPESLAAAAAAAQQLQVARKQDT----RQTATFRQQPPPMKA 188
+ + ++ E Q + E E A+ A Q LQ R+ +T R T +Q +
Sbjct: 722 EQ-KTEELEGQIKKLEADSLEVKASKEQALQDLQQQRQLNTDLELRATELSKQLEMEKEI 780
Query: 189 CLSCHQQIHRNAPICPLCKAKSRSRNPKKPKRKQD 223
S + + + K K + +K KQD
Sbjct: 781 VSSTRLDLQKKSEALESIKQKLTKQEEEKQILKQD 815
Score = 36.6 bits (83), Expect = 0.018
Identities = 43/202 (21%), Positives = 84/202 (41%), Gaps = 41/202 (20%)
Query: 3 DEQEIMCKLESIKE--------IRNKTLQMEKIKARLKAEFEALESE------------E 42
+++ +M +L ++K+ ++N + EK + KA LE E
Sbjct: 847 EKEALMTELSTVKDKLSKVSDSLKNSKSEFEKENQKGKAAILDLEKTCKELKHQLQVQME 906
Query: 43 RHLKEYKQEMDLLLQEKMAHVE---ELRLIHADINVMENTIKQSENDLNKLLESTRRLHD 99
LKE K+ L +EK A + EL + + +NT+KQ+E + +L + L
Sbjct: 907 NTLKEQKELKKSLEKEKEASHQLKLELNSMQEQLIQAQNTLKQNEKEEQQLQGNINELKQ 966
Query: 100 EYKPLKEHVDALRMTLGLQRLPDLCEEEEKLSLDYFEKQKAEWQTEPQEPPIPESLAAAA 159
+ K+ ++AL+ L + L QK E + + Q+ + ++ A
Sbjct: 967 SSEQKKKQIEALQGELKIAVL-----------------QKTELENKLQQ-QLTQAAQELA 1008
Query: 160 AAAQQLQVARKQDTRQTATFRQ 181
A +++ V + + TF+Q
Sbjct: 1009 AEKEKISVLQNNYEKSQETFKQ 1030
Score = 36.2 bits (82), Expect = 0.023
Identities = 36/168 (21%), Positives = 76/168 (45%), Gaps = 11/168 (6%)
Query: 3 DEQEIMCKLE----SIKEIRNKTLQMEKIKARLKAEFEALESEERHLKEYKQEMDLLLQE 58
D Q++ +L S+ I + + + +LK E +E++ +HLK +++ +E
Sbjct: 345 DCQQLQSRLSASETSLHRIHVELSEKGEATQKLKEELSEVETKYQHLKAEFKQLQQQREE 404
Query: 59 KMAHVEELRLIHADINVMENTIKQSENDLNKL---LESTRRLHDEYKPLKEHVDALRMTL 115
K H +L+ ++IN + + + ++E L + L+ R+L E K + + + L
Sbjct: 405 KEQHGLQLQ---SEINQLHSKLLETERQLGEAHGRLKEQRQLSSE-KLMDKEQQVADLQL 460
Query: 116 GLQRLPDLCEEEEKLSLDYFEKQKAEWQTEPQEPPIPESLAAAAAAAQ 163
L RL + +E+ S + + Q ++ + +S A AQ
Sbjct: 461 KLSRLEEQLKEKVTNSTELQHQLDKTKQQHQEQQALQQSTTAKLREAQ 508
Score = 32.7 bits (73), Expect = 0.26
Identities = 30/132 (22%), Positives = 60/132 (45%), Gaps = 8/132 (6%)
Query: 16 EIRNKTLQMEKIK---ARLKAEFEALESEERHLKEYKQEMDLLLQEKMAHVEELRLIHAD 72
EI+ K + M+K + A+L + AL +K+ Q + E ++LR +
Sbjct: 1221 EIKEKEVGMKKHEENEAKLTMQITALNENLGTVKKEWQSSQRRVSELEKQTDDLR---GE 1277
Query: 73 INVMENTIKQSENDLNKLLESTRRLHDEYKPLKEHVDALRMTLG--LQRLPDLCEEEEKL 130
I V+E T++ ++++ LLE + E + L+ V L+ L + +L E + L
Sbjct: 1278 IAVLEATVQNNQDERRALLERCLKGEGEIEKLQTKVLELQRKLDNTTAAVQELGRENQSL 1337
Query: 131 SLDYFEKQKAEW 142
+ + + +W
Sbjct: 1338 QIKHTQALNRKW 1349
Score = 31.6 bits (70), Expect = 0.57
Identities = 39/190 (20%), Positives = 84/190 (44%), Gaps = 26/190 (13%)
Query: 6 EIMCKLESIKEIRNKT-LQMEKIKARLKAEFEALESEERHLKEYKQEMDLLLQE-KMAH- 62
E+ +LE KEI + T L ++K L++ + L +E + KQ+ + L QE K+ H
Sbjct: 769 ELSKQLEMEKEIVSSTRLDLQKKSEALESIKQKLTKQEEEKQILKQDFETLSQETKIQHE 828
Query: 63 ---------VEELRLIHADINVMENTIKQSENDLNKLLESTRRLHDEYKPLKEHVDALRM 113
V EL+ + + + + ++ L+K+ +S + E++ KE+
Sbjct: 829 ELNNRIQTTVTELQKVKMEKEALMTELSTVKDKLSKVSDSLKNSKSEFE--KENQKGKAA 886
Query: 114 TLGLQR------------LPDLCEEEEKLSLDYFEKQKAEWQTEPQEPPIPESLAAAAAA 161
L L++ + + +E+++L ++++A Q + + + E L A
Sbjct: 887 ILDLEKTCKELKHQLQVQMENTLKEQKELKKSLEKEKEASHQLKLELNSMQEQLIQAQNT 946
Query: 162 AQQLQVARKQ 171
+Q + +Q
Sbjct: 947 LKQNEKEEQQ 956
>gi|31542634 filamin A interacting protein 1 [Homo sapiens]
Length = 1213
Score = 42.4 bits (98), Expect = 3e-04
Identities = 33/140 (23%), Positives = 64/140 (45%), Gaps = 5/140 (3%)
Query: 10 KLESIKE--IRNKTLQMEKI---KARLKAEFEALESEERHLKEYKQEMDLLLQEKMAHVE 64
+LE IK +NK ++ ++ +A L+ F E++ R LK Q + + E M +
Sbjct: 680 QLEEIKHQIAKNKAIEKGEVVSQEAELRHRFRLEEAKSRDLKAEVQALKEKIHELMNKED 739
Query: 65 ELRLIHADINVMENTIKQSENDLNKLLESTRRLHDEYKPLKEHVDALRMTLGLQRLPDLC 124
+L + D +V++ + EN + + L E + K + ALR ++ +R+ D+
Sbjct: 740 QLSQLQVDYSVLQQRFMEEENKNKNMGQEVLNLTKELELSKRYSRALRPSVNGRRMVDVP 799
Query: 125 EEEEKLSLDYFEKQKAEWQT 144
+ D + AE +T
Sbjct: 800 VTSTGVQTDAVSGEAAEEET 819
Score = 30.4 bits (67), Expect = 1.3
Identities = 21/96 (21%), Positives = 46/96 (47%), Gaps = 3/96 (3%)
Query: 5 QEIMCKLESIKEIRNKTLQMEKIKARLKAEFEALESEERHLKEYKQEMDLLLQEKMAHVE 64
Q++ + E +K I +K+ + + +L+ +FE S + +EM+ L + +H
Sbjct: 273 QKLREEEEKLKAITSKSKEDRQKLLKLEVDFEHKASR---FSQEHEEMNAKLANQESHNR 329
Query: 65 ELRLIHADINVMENTIKQSENDLNKLLESTRRLHDE 100
+LRL + ++++ +L K E + L D+
Sbjct: 330 QLRLKLVGLTQRIEELEETNKNLQKAEEELQELRDK 365
Score = 28.5 bits (62), Expect = 4.9
Identities = 40/171 (23%), Positives = 64/171 (37%), Gaps = 26/171 (15%)
Query: 12 ESIKEIRNKTLQMEKIKARLKAEFEALES--------EERHLKEYKQ--EMDLLLQEKMA 61
E ++E+R+K + E + L AE E L +E K Q E+ LQE+
Sbjct: 357 EELQELRDKIAKGECGNSSLMAEVENLRKRVLEMEGKDEEITKTESQCRELRKKLQEEEH 416
Query: 62 HVEELRLIHADINVMENTIKQSENDLNKLLESTRRLHDEYKPLKEHVDALRMTLGLQR-- 119
H +ELRL L K + +L + + K L + L ++
Sbjct: 417 HSKELRL--------------EVEKLQKRMSELEKLEEAFSKSKSECTQLHLNLEKEKNL 462
Query: 120 LPDLCEEEEKLSLDYFEKQKAEWQTEPQEPPIPESLAAAAAAAQQLQVARK 170
DL E E + E + +E + E E + + L + L RK
Sbjct: 463 TKDLLNELEVVKSRVKELECSESRLEKAELSLKDDLTKLKSFTVMLVDERK 513
Score = 28.5 bits (62), Expect = 4.9
Identities = 39/134 (29%), Positives = 60/134 (44%), Gaps = 30/134 (22%)
Query: 1 MADEQEIMCKLES-IKEIRNK-----------TLQMEKIKARLKAEFEALES-------- 40
M + E + K ES +E+R K L++EK++ R+ +E E LE
Sbjct: 390 MEGKDEEITKTESQCRELRKKLQEEEHHSKELRLEVEKLQKRM-SELEKLEEAFSKSKSE 448
Query: 41 -EERHL---KEYKQEMDLL--LQEKMAHVEELRLIHADINVMENTIKQSENDLNKLLEST 94
+ HL KE DLL L+ + V+EL + + E ++K +DL KL T
Sbjct: 449 CTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLEKAELSLK---DDLTKLKSFT 505
Query: 95 RRLHDEYKPLKEHV 108
L DE K + E +
Sbjct: 506 VMLVDERKNMMEKI 519
>gi|225579095 S-phase cyclin A-associated protein in the ER isoform
b [Homo sapiens]
Length = 1154
Score = 42.0 bits (97), Expect = 4e-04
Identities = 50/189 (26%), Positives = 82/189 (43%), Gaps = 29/189 (15%)
Query: 5 QEIMCKLESIKEI--RNKTLQMEKIKARLKA----EFEALESEERHLKE------YKQEM 52
+E K + ++E KTL+++K+ R K + E L+ R ++E +K+E+
Sbjct: 302 EEKQMKAQQLREKLREEKTLKLQKLLEREKDVRKWKEELLDQRRRMMEEKLLHAEFKREV 361
Query: 53 DLLLQEKMAHVEELRLIH-ADINVME---------NTIKQSENDLNKLLESTRRLHDEYK 102
L K A EE ++ A IN +E + +K+ E LN+L E +R +E +
Sbjct: 362 QLQAIVKKAQEEEAKVNEIAFINTLEAQNKRHDVLSKLKEYEQRLNELQEERQRRQEEKQ 421
Query: 103 PLKEHVDALRMTLGLQR-------LPDLCEEEEKLSLDYFEKQKAEWQTEPQEPPIPESL 155
E V + L +R L E+E ++ EK+KA + E
Sbjct: 422 ARDEAVQERKRALEAERQARVEELLMKRKEQEARIEQQRQEKEKAREDAARERARDREER 481
Query: 156 AAAAAAAQQ 164
AA AAQQ
Sbjct: 482 LAALTAAQQ 490
>gi|225579092 S-phase cyclin A-associated protein in the ER isoform
a [Homo sapiens]
Length = 1400
Score = 42.0 bits (97), Expect = 4e-04
Identities = 50/189 (26%), Positives = 82/189 (43%), Gaps = 29/189 (15%)
Query: 5 QEIMCKLESIKEI--RNKTLQMEKIKARLKA----EFEALESEERHLKE------YKQEM 52
+E K + ++E KTL+++K+ R K + E L+ R ++E +K+E+
Sbjct: 548 EEKQMKAQQLREKLREEKTLKLQKLLEREKDVRKWKEELLDQRRRMMEEKLLHAEFKREV 607
Query: 53 DLLLQEKMAHVEELRLIH-ADINVME---------NTIKQSENDLNKLLESTRRLHDEYK 102
L K A EE ++ A IN +E + +K+ E LN+L E +R +E +
Sbjct: 608 QLQAIVKKAQEEEAKVNEIAFINTLEAQNKRHDVLSKLKEYEQRLNELQEERQRRQEEKQ 667
Query: 103 PLKEHVDALRMTLGLQR-------LPDLCEEEEKLSLDYFEKQKAEWQTEPQEPPIPESL 155
E V + L +R L E+E ++ EK+KA + E
Sbjct: 668 ARDEAVQERKRALEAERQARVEELLMKRKEQEARIEQQRQEKEKAREDAARERARDREER 727
Query: 156 AAAAAAAQQ 164
AA AAQQ
Sbjct: 728 LAALTAAQQ 736
>gi|14165274 golgi-associated microtubule-binding protein HOOK3
[Homo sapiens]
Length = 718
Score = 42.0 bits (97), Expect = 4e-04
Identities = 32/116 (27%), Positives = 61/116 (52%), Gaps = 4/116 (3%)
Query: 1 MADE-QEIMCKLESIKEIRNKTLQMEKIKARLKAEFEALESEERHLKEYKQEMDLLLQEK 59
+ADE Q + +++ ++ +K ++E K + E L R +K +++ + +Q
Sbjct: 292 LADEAQSLKDEIDVLRHSSDKVSKLEGQVESYKKKLEDLGDLRRQVKLLEEKNTMYMQNT 351
Query: 60 MAHVEELRLIHADINVMENTIKQSENDLNKLLESTR---RLHDEYKPLKEHVDALR 112
++ EELR +A + +E +Q N+L E ++ +L EYK LKE VD+L+
Sbjct: 352 VSLEEELRKANAARSQLETYKRQVVELQNRLSEESKKADKLDFEYKRLKEKVDSLQ 407
>gi|239745299 PREDICTED: hypothetical protein [Homo sapiens]
Length = 523
Score = 41.6 bits (96), Expect = 6e-04
Identities = 41/163 (25%), Positives = 76/163 (46%), Gaps = 10/163 (6%)
Query: 15 KEIRNKTLQMEKIKARLKAEFEALESEERHLKEYKQEMDLLLQEKMAHVEELRLIHADIN 74
+ +R + ++ + + RL+ + E L +E L+E QE L QE+ +E RL +
Sbjct: 199 ERLREQEERLREQEERLREQEERLCEQEERLRE--QEERLREQEERLCEQEERLREHEER 256
Query: 75 VMENTIKQSENDLNKLLESTRRLHDEYKPLKEHVDALRMTLGLQRLPDLCEEEEKLSLDY 134
+ E + E + +L E RLH++ + L E + LR ++ LCE+EE+L
Sbjct: 257 LCEQEERLCEQE-ERLREQEERLHEQEERLCEQEERLR-----EQEERLCEQEERLREQE 310
Query: 135 FEKQKAEWQTEPQEPPI--PESLAAAAAAAQQLQVARKQDTRQ 175
+ E + QE + E L ++++ +Q+ RQ
Sbjct: 311 ERLCEQEERLREQEERLCEQEKLPGQERLLEEVEKLLEQERRQ 353
Score = 32.3 bits (72), Expect = 0.34
Identities = 46/167 (27%), Positives = 76/167 (45%), Gaps = 13/167 (7%)
Query: 1 MADEQEIMCKLES-IKEIRNKTLQMEKI--KARLKAEFEALESEERHLKEYKQEMDLLLQ 57
+ +++E +C+ E ++E + + EK+ + RL E E L +ER +E QE L +
Sbjct: 306 LREQEERLCEQEERLREQEERLCEQEKLPGQERLLEEVEKLLEQERRQEE--QERLLERE 363
Query: 58 EKMAHVEELRLIHADINVMENTIKQSE--NDLNKLLESTRRLHDEYKPLKEHVDALRMTL 115
+ VEEL L + + + Q E +L +L E R L ++ L E R
Sbjct: 364 RLLEEVEEL-LEQERLRQQDERLWQQETLQELERLRELERMLELGWEALYEQRAEPRS-- 420
Query: 116 GLQRLPDLCEEEEKLSLDYFEKQKAEWQTEPQEPPIPESLAAAAAAA 162
G + L + E + L L+ K+ + +EP ES AAA A
Sbjct: 421 GFEELNN--ENKSTLQLEQQVKELKK-SGGAEEPRGSESAAAARPVA 464
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 41.6 bits (96), Expect = 6e-04
Identities = 44/175 (25%), Positives = 83/175 (47%), Gaps = 22/175 (12%)
Query: 4 EQEIMCKLESIKEIRNKTLQMEKIKARLKAEFEALESEERHLKEYKQEMDLLLQEKMAHV 63
+QE+ K++ K +++ + +K +++ E+ LK+ +++LLL+E+ H+
Sbjct: 718 KQELEAKMDE-----QKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHL 772
Query: 64 EE----LRLIHADINVMENTIKQSENDLNKLLESTRRLHDEYKPLKEHVDALRMTLGLQR 119
+E + + ADI E ++Q+ L+ H++ K +E + L+ Q+
Sbjct: 773 KEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQ-----QK 827
Query: 120 LPDLCEEEEKLSLDYFEKQKAEWQTEPQEPPIPESLAAAAAAAQQL-QVARKQDT 173
L DL E E++ L KQ AE E Q+ + L A Q L Q KQ++
Sbjct: 828 LLDL--ETERILL---TKQVAE--VEAQKKDVCTELDAHKIQVQDLMQQLEKQNS 875
Score = 38.1 bits (87), Expect = 0.006
Identities = 37/190 (19%), Positives = 81/190 (42%), Gaps = 29/190 (15%)
Query: 12 ESIKEIRNKTLQMEKIKARLKAEFEALESEERHLKEYKQEMDLLLQEKMA---------- 61
E + E +E ++ R+K + L+ + ++ +K++ LL EK A
Sbjct: 269 EPVVEDGTSVKTLETLQQRVKRQENLLKRCKETIQSHKEQCTLLTSEKEALQEQLDERLQ 328
Query: 62 --------HVEELRLIHADINVMENTIKQSENDLNKLL-ESTRRLHDEYKPLKEHVDALR 112
H+ E + + +N I+Q E D ++ E+ R++H+ + +E + LR
Sbjct: 329 ELEKIKDLHMAEKTKLITQLRDAKNLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLR 388
Query: 113 -----MTLGLQRLPDLCEEEEKLSLDYFEK-----QKAEWQTEPQEPPIPESLAAAAAAA 162
MT + L + E+ E+ + + EK QK E + + E + +
Sbjct: 389 SRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTS 448
Query: 163 QQLQVARKQD 172
++ +++ +Q+
Sbjct: 449 EEERISLQQE 458
Score = 35.8 bits (81), Expect = 0.030
Identities = 36/151 (23%), Positives = 71/151 (47%), Gaps = 17/151 (11%)
Query: 1 MADEQEIMCKLESI--KEIRNKTLQMEKIKARLKAEFEALESEERHLKEYKQEMDL---L 55
M D++ M K ES E++++T ++ +++ + + +ES LK Y Q+ D+
Sbjct: 1502 MEDDKSKMEKKESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKDIEHKE 1561
Query: 56 LQEKMAHVEELRLIHADINVMENTIKQSENDLNKLLESTRRLHDEYKPLKEHVDALRMTL 115
L +K+ H +EL +N +K++E + L + E + K+ ++ + +++
Sbjct: 1562 LVQKLQHFQELG------EEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSV 1615
Query: 116 -----GLQRLPDLCEEEEKLSLDYFEKQKAE 141
L+ L D E E L K+KAE
Sbjct: 1616 KSKEEELKALEDRLESESAAKLAEL-KRKAE 1645
Score = 29.6 bits (65), Expect = 2.2
Identities = 37/195 (18%), Positives = 83/195 (42%), Gaps = 24/195 (12%)
Query: 11 LESIKEIRNKTLQMEKIKARLK-------AEFEALESEERHLKEYKQEMDLLL---QEKM 60
+E I KT+++E + LK E + L + +H +E +E D + +EK+
Sbjct: 1528 MELEDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKI 1587
Query: 61 AHVE--------ELRLIHADINVMENTIKQSENDLNKL-----LESTRRLHDEYKPLKEH 107
+E EL ++ + ++K E +L L ES +L + + ++
Sbjct: 1588 LTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAEQK 1647
Query: 108 VDALRMTLGLQRLPDLCEEEEKLSLDYFEKQKAEWQTEPQEPPIPESLAAAAAAAQQLQV 167
+ A++ L L ++ + E+ +K + + + + Q +E I E + ++Q +
Sbjct: 1648 IAAIKKQL-LSQMEEKEEQYKKGTESHLSELNTKLQEREREVHILEEKLKSVESSQSETL 1706
Query: 168 ARKQDTRQTATFRQQ 182
+ + A + +Q
Sbjct: 1707 IVPRSAKNVAAYTEQ 1721
>gi|21735548 centrosomal protein 2 [Homo sapiens]
Length = 2442
Score = 41.2 bits (95), Expect = 7e-04
Identities = 38/172 (22%), Positives = 74/172 (43%), Gaps = 4/172 (2%)
Query: 4 EQEIMCKLESIKEIRNK-TLQMEKIKARLKAEFEALESEERHLKEYKQEMDLLLQEKMAH 62
EQEI+ + ++E R + L+ + ++++L AL ++ L+ +QE ++
Sbjct: 1777 EQEIVVLQQQLQEAREQGELKEQSLQSQLDEAQRALAQRDQELEALQQEQQQAQGQEERV 1836
Query: 63 VEELRLIHADINVMENTIKQSENDLNKLLESTRRLHDEYKPLKEHVDALRMTLGLQRLPD 122
E+ + + T+K+ +L E RRL +E V AL LG R
Sbjct: 1837 KEKADALQGALEQAHMTLKERHGELQDHKEQARRLEEELAVEGRRVQALEEVLGDLRAES 1896
Query: 123 LCEEEEKLSLDY---FEKQKAEWQTEPQEPPIPESLAAAAAAAQQLQVARKQ 171
+E+ L+L + Q+ E +T + ++ A Q+L+ R +
Sbjct: 1897 REQEKALLALQQQCAEQAQEHEVETRALQDSWLQAQAVLKERDQELEALRAE 1948
Score = 36.2 bits (82), Expect = 0.023
Identities = 40/167 (23%), Positives = 79/167 (47%), Gaps = 20/167 (11%)
Query: 4 EQEIMCKLESIKEIRNKTLQMEKIKARLKAEFEALESEERHLKEYKQEMDLLLQEKMAHV 63
+Q + + E ++ + + +EK A+ E + E+++L + ++E
Sbjct: 2041 QQALAQRDEELRHQQEREQLLEKSLAQRVQE--NMIQEKQNLGQEREE------------ 2086
Query: 64 EELRLIHADINVMENTIKQSENDLNKLLESTRRLHDEYKPLKEHVDAL-RMTLGLQRL-P 121
EE+R +H + ++ T+ Q E ++ +L E+ +R + E P + +L L L P
Sbjct: 2087 EEIRGLHQSVRELQLTLAQKEQEILELRETQQRNNLEALPHSHKTSPMEEQSLKLDSLEP 2146
Query: 122 DLCEEEEKL--SLDYFEKQKAEWQTEPQEPPIPESLAAAAAAAQQLQ 166
L E E+L +L E ++ EW+ + Q+ + SLA A+ LQ
Sbjct: 2147 RLQRELERLQAALRQTEAREIEWREKAQD--LALSLAQTKASVSSLQ 2191
Score = 35.0 bits (79), Expect = 0.052
Identities = 41/174 (23%), Positives = 78/174 (44%), Gaps = 16/174 (9%)
Query: 23 QMEKIKARLKAEFEA-------LESEERHLKEYKQEMDLLLQEKMAHVEELRLIHADINV 75
Q+E +K++L A+ ++ ++ + R +EY + L +EK + L + V
Sbjct: 1011 QVEDLKSQLVAQDDSQRLVEQEVQEKLRETQEYNRIQKELEREKASLTLSLMEKEQRLLV 1070
Query: 76 MENTIKQSENDLNKLLESTRRLHDEYKPLKEHVDALRMTLGLQRLPDLCEEEEKLSLDYF 135
++ + +L+ L + + E K L ++ LR + + L +E + L
Sbjct: 1071 LQEADSIRQQELSALRQDMQEAQGEQKELSAQMELLRQEVKEKEADFLAQEAQLL----- 1125
Query: 136 EKQKAEWQTEPQEPPIPESLAAAAAAAQQLQV-ARKQDTRQTATFRQQPPPMKA 188
E+ +A TE Q + SL A A A QLQ+ R +++ A +Q P +A
Sbjct: 1126 EELEASHITEQQ---LRASLWAQEAKAAQLQLRLRSTESQLEALAAEQQPGNQA 1176
Score = 32.0 bits (71), Expect = 0.44
Identities = 35/194 (18%), Positives = 83/194 (42%), Gaps = 41/194 (21%)
Query: 11 LESIKEIRNKTLQMEKIKARLKAEF-----------EALESEERHLKE-----------Y 48
L++ KE+ + + Q+E+++ +K + L+ +R LKE
Sbjct: 935 LQTQKELADASQQLERLRQDMKVQKLKEQETTGILQTQLQEAQRELKEAARQHRDDLAAL 994
Query: 49 KQEMDLLLQEKMAHVEELRLIHADINVMENTIKQSENDLNKLLESTRRLHDEYKPLKEHV 108
++E LLQ+KM +++ + + + +++ + E ++ + L T+ EY +++ +
Sbjct: 995 QEESSSLLQDKMDLQKQVEDLKSQLVAQDDSQRLVEQEVQEKLRETQ----EYNRIQKEL 1050
Query: 109 DALRMTLGLQRLPDLCEEEEKLSLDYFEKQKAEWQTEPQEPPIPESLAAAAAAAQQLQVA 168
+ E+ L+L EK++ + + + L+A Q+ Q
Sbjct: 1051 E---------------REKASLTLSLMEKEQRLLVLQEADSIRQQELSALRQDMQEAQGE 1095
Query: 169 RKQDTRQTATFRQQ 182
+K+ + Q RQ+
Sbjct: 1096 QKELSAQMELLRQE 1109
Score = 30.4 bits (67), Expect = 1.3
Identities = 23/89 (25%), Positives = 44/89 (49%), Gaps = 7/89 (7%)
Query: 12 ESIKEIRNKTLQMEKIKARLKAEFEALESEERHLKEYKQEMDLLLQEKMAHVEELRLIHA 71
E ++ +R + ++EK + KA E L + LK+ QE+D L QE++ +E+ R +
Sbjct: 1435 EEVETLRGQIQELEKQREMQKAALELLSLD---LKKRNQEVD-LQQEQIQELEKCRSV-- 1488
Query: 72 DINVMENTIKQSENDLNKLLESTRRLHDE 100
+ + +++ E L E R L +
Sbjct: 1489 -LEHLPMAVQEREQKLTVQREQIRELEKD 1516
Score = 28.9 bits (63), Expect = 3.7
Identities = 39/175 (22%), Positives = 71/175 (40%), Gaps = 18/175 (10%)
Query: 17 IRNKTLQMEKIKARLKA-EFEALESEERHLKEYKQEMDLLLQEKMAHVEELRLIHADINV 75
I ++ Q++ +K +L E ALE EE H K Q+ + E + + L H +++
Sbjct: 1538 IESQRGQVQDLKKQLVTLECLALELEENHHKMECQQKLIKELEGQRETQRVALTHLTLDL 1597
Query: 76 MENT---------IKQSENDLNKLLESTRRLHDEYKPLKEHVDALRMTLGLQRLPDLCEE 126
E + I E+ L + E K +E ++ L+ DL
Sbjct: 1598 EERSQELQAQSSQIHDLESHSTVLARELQERDQEVKSQREQIEELQRQKE-HLTQDLERR 1656
Query: 127 EEKLSLDYFEKQKAEWQTEPQEPPIPESLAAAAAAAQQLQVARKQDTRQTATFRQ 181
+++L L Q E Q Q + E L +Q++++ ++ R+ T RQ
Sbjct: 1657 DQELMLQKERIQVLEDQRTRQTKILEEDL-------EQIKLSLRERGRELTTQRQ 1704
>gi|156104908 myosin heavy chain 6 [Homo sapiens]
Length = 1939
Score = 41.2 bits (95), Expect = 7e-04
Identities = 35/121 (28%), Positives = 51/121 (42%), Gaps = 25/121 (20%)
Query: 20 KTLQMEKIKARLKAEF----EALESEERHLKEYKQEMDLLLQEK-----MAHVEELRL-- 68
K+ + EK A +K EF E LE E KE +++M LLQEK E+ L
Sbjct: 843 KSAETEKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLND 902
Query: 69 --------------IHADINVMENTIKQSENDLNKLLESTRRLHDEYKPLKEHVDALRMT 114
+ A + M ++ E +L R+L DE LK+ +D L +T
Sbjct: 903 AEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELT 962
Query: 115 L 115
L
Sbjct: 963 L 963
Score = 30.4 bits (67), Expect = 1.3
Identities = 34/132 (25%), Positives = 63/132 (47%), Gaps = 15/132 (11%)
Query: 5 QEIMCKLESI-KEIRNKTLQMEKIKARLKAEFEALESEERHLKEYKQEMDLLLQEKMAHV 63
+E +LES KE R+ + ++ K+K A E HL+ +K+E L +E
Sbjct: 1463 EESQSELESSQKEARSLSTELFKLK-------NAYEESLEHLETFKRENKNLQEEISDLT 1515
Query: 64 EELRLIHADINVMENTIKQSE---NDLNKLLESTRRL--HDEYKPLKEHVDALRMTLGLQ 118
E+L +++ +E KQ E +L LE H+E K L+ ++ ++ ++
Sbjct: 1516 EQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIE 1575
Query: 119 RLPDLCEEEEKL 130
R L E++E++
Sbjct: 1576 R--KLAEKDEEM 1585
Score = 29.6 bits (65), Expect = 2.2
Identities = 27/120 (22%), Positives = 53/120 (44%), Gaps = 8/120 (6%)
Query: 16 EIRNKTLQMEKIKARLKAEFEALESEERHLKEYKQEMDLLLQEKMAHVEELRLIHADINV 75
+++ +E+ L+AE E L + +++ ++ L QE + E ++L+H+
Sbjct: 1668 DLKENIAIVERRNNLLQAELEELRAV---VEQTERSRKLAEQELIETSERVQLLHSQNTS 1724
Query: 76 MENTIKQSENDLNKLLESTRRL-----HDEYKPLKEHVDALRMTLGLQRLPDLCEEEEKL 130
+ N K+ E+DL +L + E K K DA M L++ D E++
Sbjct: 1725 LINQKKKMESDLTQLQSEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERM 1784
Score = 29.3 bits (64), Expect = 2.8
Identities = 35/186 (18%), Positives = 73/186 (39%), Gaps = 26/186 (13%)
Query: 15 KEIRNKTLQMEKIKARLKAEFEALESEERHLKEYKQEMDLLLQEKMAHVEELRLIHADIN 74
+E+ + ++E+ + E + E ++ +++++ + A LR HAD
Sbjct: 1143 RELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHAD-- 1200
Query: 75 VMENTIKQSENDLNKLLESTRRLHDEYKPLKEHVD--------ALRMTLGLQRLPDLCE- 125
++ + ++ L ++L E K +D ++ L+++ E
Sbjct: 1201 ----SVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLED 1256
Query: 126 ---------EEEKLSLDYFEKQKAEWQTEPQEPPIPESLAAAAAAAQQLQVARKQDTRQT 176
EE + SL+ F Q+A+ QTE E + L A QL + T+Q
Sbjct: 1257 QANEYRVKLEEAQRSLNDFTTQRAKLQTENGE--LARQLEEKEALISQLTRGKLSYTQQM 1314
Query: 177 ATFRQQ 182
++Q
Sbjct: 1315 EDLKRQ 1320
Score = 28.9 bits (63), Expect = 3.7
Identities = 34/145 (23%), Positives = 58/145 (40%), Gaps = 15/145 (10%)
Query: 21 TLQMEKIKARLKAEFEALESEERHLKEYKQEMDLLLQEKMAHVEELRLIHADINVMENTI 80
T QME +K +L+ E +A + L+ + + DLL ++ E + ++ + +
Sbjct: 1311 TQQMEDLKRQLEEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEV 1370
Query: 81 KQSENDL-NKLLESTRRLHDEYKPLKEHVDALRMTLGLQRLPDLCEEEEKLS--LDYFEK 137
Q ++ T L + K L QRL D E E ++ EK
Sbjct: 1371 AQWRTKYETDAIQRTEELEEAKKKL------------AQRLQDAEEAVEAVNAKCSSLEK 1418
Query: 138 QKAEWQTEPQEPPIPESLAAAAAAA 162
K Q E ++ + + AAAAA
Sbjct: 1419 TKHRLQNEIEDLMVDVERSNAAAAA 1443
Score = 28.1 bits (61), Expect = 6.3
Identities = 27/94 (28%), Positives = 48/94 (51%), Gaps = 10/94 (10%)
Query: 4 EQEIMCKLESIKEIRNKTLQME-KIKARLKAEFEALESEERHLKEYKQEMDLLLQEKM-- 60
E ++ ESI ++ N LQ+E K+K K EF+ +++ E +Q + L LQ+K+
Sbjct: 1058 EGDLKLTQESIMDLENDKLQLEEKLK---KKEFDI--NQQNSKIEDEQVLALQLQKKLKE 1112
Query: 61 --AHVEELRLIHADINVMENTIKQSENDLNKLLE 92
A +EEL +++ +DL++ LE
Sbjct: 1113 NQARIEELEEELEAERTARAKVEKLRSDLSRELE 1146
>gi|229577185 epidermal growth factor receptor pathway substrate 15
isoform B [Homo sapiens]
Length = 582
Score = 40.8 bits (94), Expect = 0.001
Identities = 37/151 (24%), Positives = 71/151 (47%), Gaps = 13/151 (8%)
Query: 4 EQEIMCKLESIKEIRNKTLQMEKIKARLKAEFEALESEERHLKEYKQEMD---LLLQEKM 60
EQ++ K ++IK+ ++ ++ R + L+++++ ++E E+D L+E++
Sbjct: 39 EQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEEQL 98
Query: 61 AHV-----EELRLI---HADINVMENTIKQSENDLNKLLESTRRLHDEYKPLKEHVDALR 112
V EE +LI A++ E+ I E +L K E RL E L+E V++ +
Sbjct: 99 KEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEESVESGK 158
Query: 113 MTLG--LQRLPDLCEEEEKLSLDYFEKQKAE 141
L Q L D +E + + E + E
Sbjct: 159 AQLEPLQQHLQDSQQEISSMQMKLMEMKDLE 189
Score = 37.4 bits (85), Expect = 0.010
Identities = 24/101 (23%), Positives = 50/101 (49%), Gaps = 5/101 (4%)
Query: 3 DEQEIMCKLESIKEIRNKTLQMEKIKARLKAEFEALESE----ERHLKEYKQEMDLLLQE 58
DEQ+ + E +KE+R K + ++ + LKAE + ES+ E L + ++E+ L QE
Sbjct: 88 DEQKAQLE-EQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQE 146
Query: 59 KMAHVEELRLIHADINVMENTIKQSENDLNKLLESTRRLHD 99
E + A + ++ ++ S+ +++ + + D
Sbjct: 147 TAELEESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKD 187
Score = 28.1 bits (61), Expect = 6.3
Identities = 28/127 (22%), Positives = 53/127 (41%), Gaps = 19/127 (14%)
Query: 69 IHADINVMENTIKQSENDLNKLLESTRRLHDEYKPLKEHVDALRMTLGLQRLPDLCEEEE 128
+ D+ E+TIKQ +++ L + +R E+ + ++ Q++ +L
Sbjct: 38 VEQDLKEKEDTIKQRTSEVQDLQDEVQR---------ENTNLQKLQAQKQQVQEL----- 83
Query: 129 KLSLDYFEKQKAEWQTEPQEPPIPESLAAAAAAAQQLQVARKQDTRQTATFRQQPPPMKA 188
LD ++QKA Q E Q + + A A L+ Q +T+ ++ +
Sbjct: 84 ---LDELDEQKA--QLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKARE 138
Query: 189 CLSCHQQ 195
LS QQ
Sbjct: 139 ELSRLQQ 145
>gi|4503593 epidermal growth factor receptor pathway substrate 15
isoform A [Homo sapiens]
Length = 896
Score = 40.8 bits (94), Expect = 0.001
Identities = 37/151 (24%), Positives = 71/151 (47%), Gaps = 13/151 (8%)
Query: 4 EQEIMCKLESIKEIRNKTLQMEKIKARLKAEFEALESEERHLKEYKQEMD---LLLQEKM 60
EQ++ K ++IK+ ++ ++ R + L+++++ ++E E+D L+E++
Sbjct: 353 EQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEEQL 412
Query: 61 AHV-----EELRLI---HADINVMENTIKQSENDLNKLLESTRRLHDEYKPLKEHVDALR 112
V EE +LI A++ E+ I E +L K E RL E L+E V++ +
Sbjct: 413 KEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEESVESGK 472
Query: 113 MTLG--LQRLPDLCEEEEKLSLDYFEKQKAE 141
L Q L D +E + + E + E
Sbjct: 473 AQLEPLQQHLQDSQQEISSMQMKLMEMKDLE 503
Score = 37.4 bits (85), Expect = 0.010
Identities = 24/101 (23%), Positives = 50/101 (49%), Gaps = 5/101 (4%)
Query: 3 DEQEIMCKLESIKEIRNKTLQMEKIKARLKAEFEALESE----ERHLKEYKQEMDLLLQE 58
DEQ+ + E +KE+R K + ++ + LKAE + ES+ E L + ++E+ L QE
Sbjct: 402 DEQKAQLE-EQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQE 460
Query: 59 KMAHVEELRLIHADINVMENTIKQSENDLNKLLESTRRLHD 99
E + A + ++ ++ S+ +++ + + D
Sbjct: 461 TAELEESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKD 501
Score = 32.0 bits (71), Expect = 0.44
Identities = 33/146 (22%), Positives = 61/146 (41%), Gaps = 19/146 (13%)
Query: 50 QEMDLLLQEKMAHVEELRLIHADINVMENTIKQSENDLNKLLESTRRLHDEYKPLKEHVD 109
+E+D L E + E + D+ E+TIKQ +++ L + +R E+ +
Sbjct: 333 KELDTLNNEIVDLQREKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQR---------ENTN 383
Query: 110 ALRMTLGLQRLPDLCEEEEKLSLDYFEKQKAEWQTEPQEPPIPESLAAAAAAAQQLQVAR 169
++ Q++ +L LD ++QKA Q E Q + + A A L+
Sbjct: 384 LQKLQAQKQQVQEL--------LDELDEQKA--QLEEQLKEVRKKCAEEAQLISSLKAEL 433
Query: 170 KQDTRQTATFRQQPPPMKACLSCHQQ 195
Q +T+ ++ + LS QQ
Sbjct: 434 TSQESQISTYEEELAKAREELSRLQQ 459
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 40.8 bits (94), Expect = 0.001
Identities = 36/171 (21%), Positives = 73/171 (42%), Gaps = 8/171 (4%)
Query: 12 ESIKEIRNKTLQMEKIKARLKAEFEALESEERHLKEYKQEMDLLLQEKMAHVEELRLIHA 71
E I+E K + E+ R + + E K +QE +EK+ EE+
Sbjct: 484 EKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKE 543
Query: 72 DINVMENTIKQSENDLNKLLESTRRLHDEYKPLKEHVDALRMTLGLQRLPDLCEEEEKLS 131
I+ E I++ E K+ ++HD+ + ++E + + ++ + E+EEK+
Sbjct: 544 KIHEQEEKIRKQE---EKMWRQEEKMHDQEEKIREQEEKV-----WRQEEKIREQEEKIR 595
Query: 132 LDYFEKQKAEWQTEPQEPPIPESLAAAAAAAQQLQVARKQDTRQTATFRQQ 182
+ ++ E T+ QE + E +++Q ++ RQ R+Q
Sbjct: 596 EQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQ 646
Score = 39.3 bits (90), Expect = 0.003
Identities = 40/184 (21%), Positives = 75/184 (40%), Gaps = 6/184 (3%)
Query: 4 EQEIMCKLESIKEIRNKTLQMEKIKARLKAEFEALESEERHLKEYKQEMDLLLQEKMAHV 63
EQE + + E +E Q EKI+ + + + + E+ K KQE + QE+ H
Sbjct: 509 EQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHD 568
Query: 64 EELRLIHADINVMENTIKQSENDLNKLLESTRRLHDEYKPLKEHVDALRMTLGLQRLPDL 123
+E + I E + + E + + E R ++ + +E +G Q +
Sbjct: 569 QEEK-----IREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQE-EKM 622
Query: 124 CEEEEKLSLDYFEKQKAEWQTEPQEPPIPESLAAAAAAAQQLQVARKQDTRQTATFRQQP 183
CE+EEK+ + ++ E + QE I E + +Q ++ Q +Q
Sbjct: 623 CEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQE 682
Query: 184 PPMK 187
M+
Sbjct: 683 EKMQ 686
>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 40.8 bits (94), Expect = 0.001
Identities = 40/119 (33%), Positives = 61/119 (51%), Gaps = 16/119 (13%)
Query: 12 ESIKEIRNKTLQMEKIKARL-KAEFEALESEERHLKEYKQEMDLLLQ-----EKMAHVEE 65
E+ KE+ + +KIK L K+E + E EE+ + K++ DL LQ E +A EE
Sbjct: 850 ETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEE 909
Query: 66 L--RLIHADINVMENTIKQ------SENDLN-KLLESTRRLHDEYKPLKEHVDALRMTL 115
+LI I +E IK+ E ++N +L R+L DE LK+ +D L +TL
Sbjct: 910 RCDQLIKTKIQ-LEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTL 967
Score = 33.9 bits (76), Expect = 0.12
Identities = 29/127 (22%), Positives = 60/127 (47%), Gaps = 12/127 (9%)
Query: 11 LESIKEIRNKTLQMEKIKARLKAEFEALESEERHLKEYKQEMDLLLQEKMAHVEELRLIH 70
L S ++++ + +E+ L+AE E L + L++ ++ + QE + E ++L+H
Sbjct: 1667 LRSQEDLKEQLAMVERRANLLQAEIEELRAT---LEQTERSRKIAEQELLDASERVQLLH 1723
Query: 71 ADINVMENTIKQSENDLNK-------LLESTRRLHDEYKPLKEHVDALRMTLGLQRLPDL 123
+ NT K+ E D+++ +L+ R ++ K K DA M L++ D
Sbjct: 1724 TQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAK--KAITDAAMMAEELKKEQDT 1781
Query: 124 CEEEEKL 130
E++
Sbjct: 1782 SAHLERM 1788
Score = 32.0 bits (71), Expect = 0.44
Identities = 52/218 (23%), Positives = 87/218 (39%), Gaps = 50/218 (22%)
Query: 4 EQEIMCKLESIKEIRNKTLQMEKIKARL---KAEFEA--------LESEE-------RHL 45
+QEI E I E + ++EKIK ++ K E +A LE EE L
Sbjct: 1512 QQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLEL 1571
Query: 46 KEYKQEMDLLLQEKMAHVEELRLIHADI-NVMENTI--------------KQSENDLNKL 90
+ K E+D + EK +++L+ H I M++T+ K+ E DLN++
Sbjct: 1572 NQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEM 1631
Query: 91 --------------LESTRRLHDEYKPLKEHV-DALRMTLGLQRLPDLCEEEEKLSLDYF 135
L + R K + H+ DALR L+ + E L
Sbjct: 1632 EIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEI 1691
Query: 136 EKQKAEWQTEPQEPPIPESLAAAAAAAQQLQVARKQDT 173
E+ +A + + I E A++++Q+ Q+T
Sbjct: 1692 EELRATLEQTERSRKIAEQ--ELLDASERVQLLHTQNT 1727
Score = 31.6 bits (70), Expect = 0.57
Identities = 35/155 (22%), Positives = 69/155 (44%), Gaps = 28/155 (18%)
Query: 21 TLQMEKIKARLKAEFEALESEERHLKEYKQEMDLL---LQEKMAHVEELR--LIHADINV 75
T Q+E++K +L+ E +A + L+ + + DLL +E+ EL+ L A+ V
Sbjct: 1315 TQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEV 1374
Query: 76 MENTIKQSENDLNK---LLESTRRLHDEYKPLKEHVDALR-------------------M 113
+ K + + + L E+ ++L + +EHV+A+ +
Sbjct: 1375 AQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDL 1434
Query: 114 TLGLQRLPDLCEEEEKLSLDYFEKQKAEWQTEPQE 148
L ++R C +K + F+K AEW+ + +E
Sbjct: 1435 MLDVERTNAACAALDKKQRN-FDKILAEWKQKCEE 1468
Score = 30.0 bits (66), Expect = 1.7
Identities = 34/155 (21%), Positives = 63/155 (40%), Gaps = 7/155 (4%)
Query: 20 KTLQMEKIKARLKAEFEALESEERHLKEYKQEMDLLLQEKMAHVEELRLIHADINVMENT 79
+T ++E+ K +L +A E + ++ Q VE+L L N
Sbjct: 1388 RTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAA 1447
Query: 80 IKQSENDLNKLLESTRRLHDEYKPLKEHVDALRMTLG--LQRLPDLCEEEEKLSLDYFEK 137
+ + + + +K+L ++ +E E +LG L ++ + EE SLD E
Sbjct: 1448 LDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEE----SLDQLET 1503
Query: 138 QKAEWQTEPQE-PPIPESLAAAAAAAQQLQVARKQ 171
K E + QE + E +A +L+ +KQ
Sbjct: 1504 LKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQ 1538
Score = 30.0 bits (66), Expect = 1.7
Identities = 31/129 (24%), Positives = 65/129 (50%), Gaps = 9/129 (6%)
Query: 5 QEIMCKLE-SIKEIRNKTLQMEKIKARLKAEFEALESEERHLKEYKQEMDLLLQEKMAHV 63
+E +LE S KE R+ ++ KIK + + LE+ +R K +QE+ L ++
Sbjct: 1467 EETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQ---IA 1523
Query: 64 EELRLIHADINVMENTIKQSENDLNKLLESTRRL--HDEYKPLKEHVDALRMTLGLQRLP 121
E + IH ++ ++ ++Q + +L LE H+E K L+ ++ ++ + R
Sbjct: 1524 EGGKRIH-ELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDR-- 1580
Query: 122 DLCEEEEKL 130
+ E++E++
Sbjct: 1581 KIAEKDEEI 1589
>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 40.8 bits (94), Expect = 0.001
Identities = 40/119 (33%), Positives = 61/119 (51%), Gaps = 16/119 (13%)
Query: 12 ESIKEIRNKTLQMEKIKARL-KAEFEALESEERHLKEYKQEMDLLLQ-----EKMAHVEE 65
E+ KE+ + +KIK L K+E + E EE+ + K++ DL LQ E +A EE
Sbjct: 850 ETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEE 909
Query: 66 L--RLIHADINVMENTIKQ------SENDLN-KLLESTRRLHDEYKPLKEHVDALRMTL 115
+LI I +E IK+ E ++N +L R+L DE LK+ +D L +TL
Sbjct: 910 RCDQLIKTKIQ-LEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTL 967
Score = 33.9 bits (76), Expect = 0.12
Identities = 29/127 (22%), Positives = 60/127 (47%), Gaps = 12/127 (9%)
Query: 11 LESIKEIRNKTLQMEKIKARLKAEFEALESEERHLKEYKQEMDLLLQEKMAHVEELRLIH 70
L S ++++ + +E+ L+AE E L + L++ ++ + QE + E ++L+H
Sbjct: 1667 LRSQEDLKEQLAMVERRANLLQAEIEELRAT---LEQTERSRKIAEQELLDASERVQLLH 1723
Query: 71 ADINVMENTIKQSENDLNK-------LLESTRRLHDEYKPLKEHVDALRMTLGLQRLPDL 123
+ NT K+ E D+++ +L+ R ++ K K DA M L++ D
Sbjct: 1724 TQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAK--KAITDAAMMAEELKKEQDT 1781
Query: 124 CEEEEKL 130
E++
Sbjct: 1782 SAHLERM 1788
Score = 32.0 bits (71), Expect = 0.44
Identities = 52/218 (23%), Positives = 87/218 (39%), Gaps = 50/218 (22%)
Query: 4 EQEIMCKLESIKEIRNKTLQMEKIKARL---KAEFEA--------LESEE-------RHL 45
+QEI E I E + ++EKIK ++ K E +A LE EE L
Sbjct: 1512 QQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLEL 1571
Query: 46 KEYKQEMDLLLQEKMAHVEELRLIHADI-NVMENTI--------------KQSENDLNKL 90
+ K E+D + EK +++L+ H I M++T+ K+ E DLN++
Sbjct: 1572 NQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEM 1631
Query: 91 --------------LESTRRLHDEYKPLKEHV-DALRMTLGLQRLPDLCEEEEKLSLDYF 135
L + R K + H+ DALR L+ + E L
Sbjct: 1632 EIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEI 1691
Query: 136 EKQKAEWQTEPQEPPIPESLAAAAAAAQQLQVARKQDT 173
E+ +A + + I E A++++Q+ Q+T
Sbjct: 1692 EELRATLEQTERSRKIAEQ--ELLDASERVQLLHTQNT 1727
Score = 31.6 bits (70), Expect = 0.57
Identities = 35/155 (22%), Positives = 69/155 (44%), Gaps = 28/155 (18%)
Query: 21 TLQMEKIKARLKAEFEALESEERHLKEYKQEMDLL---LQEKMAHVEELR--LIHADINV 75
T Q+E++K +L+ E +A + L+ + + DLL +E+ EL+ L A+ V
Sbjct: 1315 TQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEV 1374
Query: 76 MENTIKQSENDLNK---LLESTRRLHDEYKPLKEHVDALR-------------------M 113
+ K + + + L E+ ++L + +EHV+A+ +
Sbjct: 1375 AQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDL 1434
Query: 114 TLGLQRLPDLCEEEEKLSLDYFEKQKAEWQTEPQE 148
L ++R C +K + F+K AEW+ + +E
Sbjct: 1435 MLDVERTNAACAALDKKQRN-FDKILAEWKQKCEE 1468
Score = 30.0 bits (66), Expect = 1.7
Identities = 34/155 (21%), Positives = 63/155 (40%), Gaps = 7/155 (4%)
Query: 20 KTLQMEKIKARLKAEFEALESEERHLKEYKQEMDLLLQEKMAHVEELRLIHADINVMENT 79
+T ++E+ K +L +A E + ++ Q VE+L L N
Sbjct: 1388 RTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAA 1447
Query: 80 IKQSENDLNKLLESTRRLHDEYKPLKEHVDALRMTLG--LQRLPDLCEEEEKLSLDYFEK 137
+ + + + +K+L ++ +E E +LG L ++ + EE SLD E
Sbjct: 1448 LDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEE----SLDQLET 1503
Query: 138 QKAEWQTEPQE-PPIPESLAAAAAAAQQLQVARKQ 171
K E + QE + E +A +L+ +KQ
Sbjct: 1504 LKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQ 1538
Score = 30.0 bits (66), Expect = 1.7
Identities = 31/129 (24%), Positives = 65/129 (50%), Gaps = 9/129 (6%)
Query: 5 QEIMCKLE-SIKEIRNKTLQMEKIKARLKAEFEALESEERHLKEYKQEMDLLLQEKMAHV 63
+E +LE S KE R+ ++ KIK + + LE+ +R K +QE+ L ++
Sbjct: 1467 EETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQ---IA 1523
Query: 64 EELRLIHADINVMENTIKQSENDLNKLLESTRRL--HDEYKPLKEHVDALRMTLGLQRLP 121
E + IH ++ ++ ++Q + +L LE H+E K L+ ++ ++ + R
Sbjct: 1524 EGGKRIH-ELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDR-- 1580
Query: 122 DLCEEEEKL 130
+ E++E++
Sbjct: 1581 KIAEKDEEI 1589
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 40.4 bits (93), Expect = 0.001
Identities = 43/227 (18%), Positives = 99/227 (43%), Gaps = 10/227 (4%)
Query: 1 MADEQEIMC-KLESIKEIRNKTLQMEKIKARLKAEFEALESEERHLKEYKQEMDLLLQEK 59
M ++E+M K E I+E+ K + EKI+ + + E + E+ K +QE + QE+
Sbjct: 332 MRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQE-KRQEQEAKMWRQEE 390
Query: 60 MAHVEELRLIHADINVMENTIKQSENDLNKLLESTRRLHDEYKPLKEHVDALRMTLGLQR 119
+E ++ + + E K E + K+ E + ++ + ++ + +R ++
Sbjct: 391 KIREQEEKIREQEEMMQEQEEKMGEQE-EKMWEQEEEMQEQEEKMRRQEEKIR-----EQ 444
Query: 120 LPDLCEEEEKLSLDYFEKQKAEWQTEPQEPPIPESLAAAAAAAQQLQVARKQDTRQTATF 179
+ E+EEK+ Q+ E + QE + E A ++++ ++ Q
Sbjct: 445 EKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKI 504
Query: 180 RQQPPPMKACLSCHQQIHRN--APICPLCKAKSRSRNPKKPKRKQDE 224
R+Q ++ Q+ +C+ + + + ++ R+Q+E
Sbjct: 505 REQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEE 551
>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
sapiens]
Length = 1939
Score = 40.4 bits (93), Expect = 0.001
Identities = 39/119 (32%), Positives = 60/119 (50%), Gaps = 16/119 (13%)
Query: 12 ESIKEIRNKTLQMEKIKARL-KAEFEALESEERHLKEYKQEMDLLLQ-----EKMAHVEE 65
E+ KE+ N + EK K L K E + E EE+ + +++ DL LQ + +A EE
Sbjct: 848 ETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADSLADAEE 907
Query: 66 L--RLIHADINVMENTIKQ------SENDLN-KLLESTRRLHDEYKPLKEHVDALRMTL 115
+LI I +E IK+ E ++N +L R+L DE LK+ +D L +TL
Sbjct: 908 RCDQLIKTKIQ-LEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTL 965
Score = 33.1 bits (74), Expect = 0.20
Identities = 28/125 (22%), Positives = 58/125 (46%), Gaps = 8/125 (6%)
Query: 11 LESIKEIRNKTLQMEKIKARLKAEFEALESEERHLKEYKQEMDLLLQEKMAHVEELRLIH 70
L S ++++ + +E+ L+AE E L + L++ ++ + QE + E ++L+H
Sbjct: 1665 LRSQEDLKEQLAMVERRANLLQAEIEELRAT---LEQTERSRKIAEQELLDASERVQLLH 1721
Query: 71 ADINVMENTIKQSENDLNKLLESTRRL-----HDEYKPLKEHVDALRMTLGLQRLPDLCE 125
+ NT K+ E D++++ + + E K K DA M L++ D
Sbjct: 1722 TQNTSLINTKKKLETDISQIQGEMEDIIQEARNAEEKAKKAITDAAMMAEELKKEQDTSA 1781
Query: 126 EEEKL 130
E++
Sbjct: 1782 HLERM 1786
Score = 32.3 bits (72), Expect = 0.34
Identities = 31/129 (24%), Positives = 67/129 (51%), Gaps = 9/129 (6%)
Query: 5 QEIMCKLE-SIKEIRNKTLQMEKIKARLKAEFEALESEERHLKEYKQEMDLLLQEKMAHV 63
+E +LE S KE R+ + ++ KIK + + LE+ +R K +QE+ L ++
Sbjct: 1465 EETHAELEASQKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQ---IA 1521
Query: 64 EELRLIHADINVMENTIKQSENDLNKLLESTRRL--HDEYKPLKEHVDALRMTLGLQRLP 121
E + IH ++ ++ ++Q +++L LE H+E K L+ ++ ++ + R
Sbjct: 1522 EGGKRIH-ELEKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDR-- 1578
Query: 122 DLCEEEEKL 130
+ E++E++
Sbjct: 1579 KIAEKDEEI 1587
Score = 31.6 bits (70), Expect = 0.57
Identities = 52/218 (23%), Positives = 90/218 (41%), Gaps = 50/218 (22%)
Query: 4 EQEIMCKLESIKEIRNKTLQMEKIKARL---KAEFEA--------LESEE-------RHL 45
+QEI E I E + ++EKIK ++ K+E +A LE EE L
Sbjct: 1510 QQEISDLTEQIAEGGKRIHELEKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLEL 1569
Query: 46 KEYKQEMDLLLQEKMAHVEELRLIHADI-NVMENTI--------------KQSENDLNKL 90
+ K E+D + EK +++++ H I M++T+ K+ E DLN++
Sbjct: 1570 NQVKSEVDRKIAEKDEEIDQMKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEM 1629
Query: 91 -----------LESTRRLHDEYKPLKE---HV-DALRMTLGLQRLPDLCEEEEKLSLDYF 135
E+ R + LK+ H+ DALR L+ + E L
Sbjct: 1630 EIQLNHANRMAAEALRNYRNTQAILKDTQLHLDDALRSQEDLKEQLAMVERRANLLQAEI 1689
Query: 136 EKQKAEWQTEPQEPPIPESLAAAAAAAQQLQVARKQDT 173
E+ +A + + I E A++++Q+ Q+T
Sbjct: 1690 EELRATLEQTERSRKIAEQ--ELLDASERVQLLHTQNT 1725
Score = 29.6 bits (65), Expect = 2.2
Identities = 33/155 (21%), Positives = 67/155 (43%), Gaps = 28/155 (18%)
Query: 21 TLQMEKIKARLKAEFEALESEERHLKEYKQEMDLLL----QEKMAHVEELRLIHADINVM 76
T Q+E++K +L+ E +A + L+ + + DLL +E+ A E R + + +
Sbjct: 1313 TQQIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQEAKAELQRAMSKANSEV 1372
Query: 77 ENTIKQSEND----LNKLLESTRRLHDEYKPLKEHVDALR-------------------M 113
+ E D +L E+ ++L + +EHV+A+ +
Sbjct: 1373 AQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDL 1432
Query: 114 TLGLQRLPDLCEEEEKLSLDYFEKQKAEWQTEPQE 148
+ ++R C +K + F+K AEW+ + +E
Sbjct: 1433 MIDVERTNAACAALDKKQRN-FDKILAEWKQKCEE 1466
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.127 0.357
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,991,998
Number of Sequences: 37866
Number of extensions: 432888
Number of successful extensions: 4190
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 167
Number of HSP's successfully gapped in prelim test: 487
Number of HSP's that attempted gapping in prelim test: 2916
Number of HSP's gapped (non-prelim): 1594
length of query: 224
length of database: 18,247,518
effective HSP length: 98
effective length of query: 126
effective length of database: 14,536,650
effective search space: 1831617900
effective search space used: 1831617900
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.