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Search of human proteins with 8923179
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|8923179 F-box and leucine-rich repeat protein 12 [Homo
sapiens]
(326 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|8923179 F-box and leucine-rich repeat protein 12 [Homo sapiens] 660 0.0
gi|6912466 F-box and leucine-rich repeat protein 7 [Homo sapiens] 73 3e-13
gi|27734755 F-box and leucine-rich repeat protein 20 [Homo sapiens] 62 7e-10
gi|16306582 F-box and leucine-rich repeat protein 2 [Homo sapiens] 57 3e-08
gi|16306595 S-phase kinase-associated protein 2 isoform 1 [Homo ... 52 5e-07
gi|14249170 S-phase kinase-associated protein 2 isoform 2 [Homo ... 52 5e-07
gi|22748931 F-box and leucine-rich repeat protein 14 [Homo sapiens] 51 2e-06
gi|24025682 F-box and leucine-rich repeat protein 16 [Homo sapiens] 44 3e-04
gi|148922963 F-box and leucine-rich repeat protein 21 [Homo sapi... 43 4e-04
gi|30089926 F-box only protein 11 isoform 1 [Homo sapiens] 42 6e-04
gi|30089924 F-box only protein 11 isoform 2 [Homo sapiens] 42 6e-04
gi|30089922 F-box only protein 11 isoform 3 [Homo sapiens] 42 6e-04
gi|16306580 F-box and leucine-rich repeat protein 11 [Homo sapiens] 41 0.001
gi|229576894 F-box and WD repeat domain containing 12 isoform 2 ... 41 0.002
gi|229576873 F-box and WD repeat domain containing 12 isoform 1 ... 41 0.002
gi|54112382 F-box and leucine-rich repeat protein 10 isoform a [... 41 0.002
gi|54112380 F-box and leucine-rich repeat protein 10 isoform b [... 41 0.002
gi|161333854 F-box and leucine-rich repeat protein 13 isoform 2 ... 40 0.002
gi|23397500 F-box protein 39 [Homo sapiens] 39 0.005
gi|8922188 F-box only protein 6 [Homo sapiens] 39 0.005
gi|16306574 F-box and leucine-rich repeat protein 5 isoform 2 [H... 39 0.005
gi|16306572 F-box and leucine-rich repeat protein 5 isoform 1 [H... 39 0.005
gi|15812198 F-box only protein 2 [Homo sapiens] 39 0.005
gi|161333852 F-box and leucine-rich repeat protein 13 isoform 1 ... 39 0.006
gi|124248558 F-box and WD-40 domain protein 9 [Homo sapiens] 39 0.006
gi|83035136 F-box protein 31 [Homo sapiens] 39 0.008
gi|16306584 F-box and leucine-rich repeat protein 3 [Homo sapiens] 39 0.008
gi|34878749 F-box protein 44 isoform 2 [Homo sapiens] 39 0.008
gi|34878735 F-box protein 44 isoform 1 [Homo sapiens] 39 0.008
gi|34878753 F-box protein 44 isoform 2 [Homo sapiens] 39 0.008
>gi|8923179 F-box and leucine-rich repeat protein 12 [Homo sapiens]
Length = 326
Score = 660 bits (1704), Expect = 0.0
Identities = 326/326 (100%), Positives = 326/326 (100%)
Query: 1 MATLVELPDSVLLEIFSYLPVRDRIRISRVCHRWKRLVDDRWLWRHVDLTLYTMRPKVMW 60
MATLVELPDSVLLEIFSYLPVRDRIRISRVCHRWKRLVDDRWLWRHVDLTLYTMRPKVMW
Sbjct: 1 MATLVELPDSVLLEIFSYLPVRDRIRISRVCHRWKRLVDDRWLWRHVDLTLYTMRPKVMW 60
Query: 61 HLLRRYMASRLHSLRMGGYLFSGSQAPQLSPALLRALGQKCPNLKRLCLHVADLSMVPIT 120
HLLRRYMASRLHSLRMGGYLFSGSQAPQLSPALLRALGQKCPNLKRLCLHVADLSMVPIT
Sbjct: 61 HLLRRYMASRLHSLRMGGYLFSGSQAPQLSPALLRALGQKCPNLKRLCLHVADLSMVPIT 120
Query: 121 SLPSTLRTLELHSCEISMAWLHKQQDPTVLPLLECIVLDRVPAFRDEHLQGLTRFRALRS 180
SLPSTLRTLELHSCEISMAWLHKQQDPTVLPLLECIVLDRVPAFRDEHLQGLTRFRALRS
Sbjct: 121 SLPSTLRTLELHSCEISMAWLHKQQDPTVLPLLECIVLDRVPAFRDEHLQGLTRFRALRS 180
Query: 181 LVLGGTYRVTETGLDAGLQELSYLQRLEVLGCTLSADSTLLAISRHLRDVRKIRLTVRGL 240
LVLGGTYRVTETGLDAGLQELSYLQRLEVLGCTLSADSTLLAISRHLRDVRKIRLTVRGL
Sbjct: 181 LVLGGTYRVTETGLDAGLQELSYLQRLEVLGCTLSADSTLLAISRHLRDVRKIRLTVRGL 240
Query: 241 SAPGLAVLEGMPALESLCLQGPLVTPEMPSPTEILSSCLTMPKLRVLELQGLGWEGQEAE 300
SAPGLAVLEGMPALESLCLQGPLVTPEMPSPTEILSSCLTMPKLRVLELQGLGWEGQEAE
Sbjct: 241 SAPGLAVLEGMPALESLCLQGPLVTPEMPSPTEILSSCLTMPKLRVLELQGLGWEGQEAE 300
Query: 301 KILCKGLPHCMVIVRACPKESMDWWM 326
KILCKGLPHCMVIVRACPKESMDWWM
Sbjct: 301 KILCKGLPHCMVIVRACPKESMDWWM 326
>gi|6912466 F-box and leucine-rich repeat protein 7 [Homo sapiens]
Length = 491
Score = 73.2 bits (178), Expect = 3e-13
Identities = 69/258 (26%), Positives = 114/258 (44%), Gaps = 31/258 (12%)
Query: 2 ATLVELPDSVLLEIFSYLPVRDRIRISRVCHRWKRLVDDRWLWRHVDLTLYTMRPKVMWH 61
A++ LPD +++IFS+LP R +RVC RW L D LWR + LT T+
Sbjct: 112 ASIDRLPDHSMVQIFSFLPTNQLCRCARVCRRWYNLAWDPRLWRTIRLTGETINVDRALK 171
Query: 62 LLRRYMASRLHSLRMGGYLFSGSQAPQLSPALLRALGQKCPNLKRL----CLHVADLSMV 117
+L R + ++ + + S +L+ L + Q CP L+RL C ++++ ++
Sbjct: 172 VLTRRLCQDTPNVCLMLETVTVSGCRRLTDRGLYTIAQCCPELRRLEVSGCYNISNEAVF 231
Query: 118 PITSLPSTLRTLELHSC------------EISMAWLH-KQQDPTVLPLLECIVLDRVPAF 164
+ SL L L++ C I ++ LH KQ L + +C VL+
Sbjct: 232 DVVSLCPNLEHLDVSGCSKVTCISLTREASIKLSPLHGKQISIRYLDMTDCFVLE----- 286
Query: 165 RDEHLQGL-TRFRALRSLVLGGTYRVTETGLDAGLQELSYLQRLEVLGCTLSADSTLLAI 223
DE L + L L L R+T+ GL + + ++ L V C +D
Sbjct: 287 -DEGLHTIAAHCTQLTHLYLRRCVRLTDEGLRYLVIYCASIKELSVSDCRFVSDF----- 340
Query: 224 SRHLRDVRKIRLTVRGLS 241
LR++ K+ +R LS
Sbjct: 341 --GLREIAKLESRLRYLS 356
>gi|27734755 F-box and leucine-rich repeat protein 20 [Homo sapiens]
Length = 436
Score = 62.0 bits (149), Expect = 7e-10
Identities = 76/294 (25%), Positives = 122/294 (41%), Gaps = 50/294 (17%)
Query: 6 ELPDSVLLEIFSYLPVRDRIRISRVCHRWKRLVDDRWLWRHVDLTLY--TMRPKVMWHLL 63
+LP +LL IFS+L V R ++V W L D W+ +DL + + +V+ ++
Sbjct: 27 KLPKELLLRIFSFLDVVTLCRCAQVSRAWNVLALDGSNWQRIDLFDFQRDIEGRVVENIS 86
Query: 64 RRYMASRLHSLRMGGYLFSGSQAPQLSPALLRALGQKCPNLKRL----CLHVADLSMVPI 119
+R L L + G L G A LR Q C N++ L C D + +
Sbjct: 87 KR-CGGFLRKLSLRGCLGVGDNA-------LRTFAQNCRNIEVLNLNGCTKTTDATCTSL 138
Query: 120 TSLPSTLRTLELHSCEISMAWLHKQQDPTVLPLLECIVLDRVPAFRDEHLQGLTRFRALR 179
+ S LR L+L SC S+ + + PLLE
Sbjct: 139 SKFCSKLRHLDLASC-TSITNMSLKALSEGCPLLE------------------------- 172
Query: 180 SLVLGGTYRVTETGLDAGLQELSYLQRLEVLGCTLSADSTLLAISRHLRDVRKIRL-TVR 238
L + +VT+ G+ A ++ L+ L + GCT D L I H ++ + L T
Sbjct: 173 QLNISWCDQVTKDGIQALVRGCGGLKALFLKGCTQLEDEALKYIGAHCPELVTLNLQTCL 232
Query: 239 GLSAPGL-AVLEGMPALESLCLQGPLVTPEMPSPTEILSSCL--TMPKLRVLEL 289
++ GL + G L+SLC G + T+ + + L P+LR+LE+
Sbjct: 233 QITDEGLITICRGCHKLQSLCASG------CSNITDAILNALGQNCPRLRILEV 280
>gi|16306582 F-box and leucine-rich repeat protein 2 [Homo sapiens]
Length = 423
Score = 56.6 bits (135), Expect = 3e-08
Identities = 65/296 (21%), Positives = 123/296 (41%), Gaps = 56/296 (18%)
Query: 6 ELPDSVLLEIFSYLPVRDRIRISRVCHRWKRLVDDRWLWRHVDLTLY--TMRPKVMWHLL 63
+LP +LL IFS+L + R +++ W L D W+ +DL + + +V+ ++
Sbjct: 14 KLPKELLLRIFSFLDIVTLCRCAQISKAWNILALDGSNWQRIDLFNFQIDVEGRVVENIS 73
Query: 64 RRYMASRLHSLRMGGYLFSGSQAPQLSPALLRALGQKCPNLKRL----CLHVADLSMVPI 119
+R L L + G + G + L+ Q C N++ L C + D + +
Sbjct: 74 KR-CGGFLRKLSLRGCIGVGDSS-------LKTFAQNCRNIEHLNLNGCTKITDSTCYSL 125
Query: 120 TSLPSTLRTLELHSCEISMAWLHKQQDPTVLPLLECIVLDRVPAFRDEHLQGLTR-FRAL 178
+ S L+ L+L SC + + L+G++ R L
Sbjct: 126 SRFCSKLKHLDLTSC---------------------------VSITNSSLKGISEGCRNL 158
Query: 179 RSLVLGGTYRVTETGLDAGLQELSYLQRLEVLGCTLSADSTLLAISRHLRDVRKI----- 233
L L ++T+ G++A ++ L+ L + GCT D L I + ++ +
Sbjct: 159 EYLNLSWCDQITKDGIEALVRGCRGLKALLLRGCTQLEDEALKHIQNYCHELVSLNLQSC 218
Query: 234 -RLTVRGLSAPGLAVLEGMPALESLCLQGPLVTPEMPSPTEILSSCLTMPKLRVLE 288
R+T G+ + + G L++LCL G + + + L P+L++LE
Sbjct: 219 SRITDEGV----VQICRGCHRLQALCLSG----CSNLTDASLTALGLNCPRLQILE 266
Score = 30.4 bits (67), Expect = 2.2
Identities = 37/164 (22%), Positives = 66/164 (40%), Gaps = 18/164 (10%)
Query: 84 SQAPQLSPALLRALGQKCPNLKRL----CLHVADLSMVPITSLPSTLRTLELHSCEISMA 139
S Q++ + AL + C LK L C + D ++ I + L +L L SC
Sbjct: 164 SWCDQITKDGIEALVRGCRGLKALLLRGCTQLEDEALKHIQNYCHELVSLNLQSCS---- 219
Query: 140 WLHKQQDPTVLPL------LECIVLDRVPAFRDEHLQGL-TRFRALRSLVLGGTYRVTET 192
+ D V+ + L+ + L D L L L+ L +T+
Sbjct: 220 ---RITDEGVVQICRGCHRLQALCLSGCSNLTDASLTALGLNCPRLQILEAARCSHLTDA 276
Query: 193 GLDAGLQELSYLQRLEVLGCTLSADSTLLAISRHLRDVRKIRLT 236
G + L+++++ C L DSTL+ +S H ++ + L+
Sbjct: 277 GFTLLARNCHELEKMDLEECILITDSTLIQLSIHCPKLQALSLS 320
>gi|16306595 S-phase kinase-associated protein 2 isoform 1 [Homo
sapiens]
Length = 424
Score = 52.4 bits (124), Expect = 5e-07
Identities = 26/57 (45%), Positives = 35/57 (61%)
Query: 7 LPDSVLLEIFSYLPVRDRIRISRVCHRWKRLVDDRWLWRHVDLTLYTMRPKVMWHLL 63
LPD +LL IFS L + + +++S VC RW RL D LW+ +DLT + P V LL
Sbjct: 100 LPDELLLGIFSCLCLPELLKVSGVCKRWYRLASDESLWQTLDLTGKNLHPDVTGRLL 156
>gi|14249170 S-phase kinase-associated protein 2 isoform 2 [Homo
sapiens]
Length = 410
Score = 52.4 bits (124), Expect = 5e-07
Identities = 26/57 (45%), Positives = 35/57 (61%)
Query: 7 LPDSVLLEIFSYLPVRDRIRISRVCHRWKRLVDDRWLWRHVDLTLYTMRPKVMWHLL 63
LPD +LL IFS L + + +++S VC RW RL D LW+ +DLT + P V LL
Sbjct: 100 LPDELLLGIFSCLCLPELLKVSGVCKRWYRLASDESLWQTLDLTGKNLHPDVTGRLL 156
>gi|22748931 F-box and leucine-rich repeat protein 14 [Homo sapiens]
Length = 418
Score = 50.8 bits (120), Expect = 2e-06
Identities = 76/285 (26%), Positives = 118/285 (41%), Gaps = 47/285 (16%)
Query: 11 VLLEIFSYLPVRDRIRISRVCHRWKRLVDDRWLWRHVDLTLYTMRP-------------- 56
+L IF YL VRD+ R ++VC W+ + +WR V+ L+ R
Sbjct: 12 LLAMIFGYLDVRDKGRAAQVCTAWRDAAYHKSVWRGVEAKLHLRRANPSLFPSLQARGIR 71
Query: 57 KVMWHLLRRYMA------SRLHSLRMGG-YLFSGSQAPQLSPALLRALGQKCPNLKRLCL 109
+V LRR ++ + + SL + G Y + + L A ++ +G LC
Sbjct: 72 RVQILSLRRSLSYVIQGMANIESLNLSGCYNLTDN---GLGHAFVQEIGSLRALNLSLCK 128
Query: 110 HVADLSMVPITSLPSTLRTLELHSCE-------ISMAWLHKQQDPTVLPLLECIVLDRVP 162
+ D S+ I L LEL C + +AW Q L L C L V
Sbjct: 129 QITDSSLGRIAQYLKGLEVLELGGCSNITNTGLLLIAW--GLQRLKSLNLRSCRHLSDVG 186
Query: 163 AFRDEHLQGLTRFRA-----LRSLVLGGTYRVTETGLDAGLQELSYLQRLEVLGCTLSAD 217
HL G+TR A L L L ++T+ L + L+ L+ L + C +D
Sbjct: 187 I---GHLAGMTRSAAEGCLGLEQLTLQDCQKLTDLSLKHISRGLTGLRLLNLSFCGGISD 243
Query: 218 STLLAISRHLRDVRKIRL-TVRGLSAPGLAVLEGMPALESLCLQG 261
+ LL +S H+ +R + L + +S G+ L A+ SL L G
Sbjct: 244 AGLLHLS-HMGSLRSLNLRSCDNISDTGIMHL----AMGSLRLSG 283
Score = 33.5 bits (75), Expect = 0.26
Identities = 28/113 (24%), Positives = 54/113 (47%), Gaps = 11/113 (9%)
Query: 106 RLCLHVADLSMVPITSLPSTLRTLELHSCEI----SMAWLHKQQDPTV-LPLLECIVLDR 160
R C +++D ++ + L L++ C+ S+A++ + D L L C + D
Sbjct: 261 RSCDNISDTGIMHLAMGSLRLSGLDVSFCDKVGDQSLAYIAQGLDGLKSLSLCSCHISD- 319
Query: 161 VPAFRDEHLQGLTRFRALRSLVLGGTYRVTETGLDAGLQELSYLQRLEVLGCT 213
D + + + LR+L +G R+T+ GL+ + LS L +++ GCT
Sbjct: 320 -----DGINRMVRQMHGLRTLNIGQCVRITDKGLELIAEHLSQLTGIDLYGCT 367
>gi|24025682 F-box and leucine-rich repeat protein 16 [Homo sapiens]
Length = 479
Score = 43.5 bits (101), Expect = 3e-04
Identities = 68/230 (29%), Positives = 98/230 (42%), Gaps = 21/230 (9%)
Query: 94 LRALGQKCPNLKRLCL---HVADLSMVPITSLPS-TLRTLELHSC-EIS----MAWLHKQ 144
+ A+ Q PNL L L HV D ++ T+ + TL L SC EI+ + +H
Sbjct: 260 IAAISQLLPNLAELSLQAYHVTDTALAYFTARQGHSTHTLRLLSCWEITNHGVVNVVHSL 319
Query: 145 QDPTVLPLLECI-VLDRVPAFRDEHLQGLTRFRALRSLVLGGTYRVTETGLDAGLQELSY 203
+ T L L C V D E+L R LRSL L R+T+ L+ +L
Sbjct: 320 PNLTALSLSGCSKVTDDGVELVAENL------RKLRSLDLSWCPRITDMALEYVACDLHR 373
Query: 204 LQRLEVLGCTLSADSTLLAISRHLRDVRKIRLTVRGLSAPGLAVLEGMPALESLCLQGPL 263
L+ L + C D+ L +S + +R + L R L+ + AL SL L P
Sbjct: 374 LEELVLDRCVRITDTGLSYLST-MSSLRSLYL--RWCCQVQDFGLKHLLALGSLRLLSPA 430
Query: 264 VTPEMPSPTEILSSCLTMPKLRVLELQGLGWEGQEAEKILCKGLPHCMVI 313
P + T LS + + +L LEL E K + LP C+VI
Sbjct: 431 GCPLLT--TTGLSGLVQLQELEELELTNCPGATPELFKYFSQHLPRCLVI 478
>gi|148922963 F-box and leucine-rich repeat protein 21 [Homo
sapiens]
Length = 434
Score = 42.7 bits (99), Expect = 4e-04
Identities = 20/45 (44%), Positives = 25/45 (55%)
Query: 7 LPDSVLLEIFSYLPVRDRIRISRVCHRWKRLVDDRWLWRHVDLTL 51
LP V+L+IF YLP+ DR S VC RW + LWR + L
Sbjct: 45 LPHHVVLQIFQYLPLLDRACASSVCRRWNEVFHISDLWRKFEFEL 89
>gi|30089926 F-box only protein 11 isoform 1 [Homo sapiens]
Length = 843
Score = 42.4 bits (98), Expect = 6e-04
Identities = 19/47 (40%), Positives = 31/47 (65%)
Query: 6 ELPDSVLLEIFSYLPVRDRIRISRVCHRWKRLVDDRWLWRHVDLTLY 52
+LPD V+L+IFSYL +D R + VC R+ L +D LW+ + + ++
Sbjct: 74 KLPDEVVLKIFSYLLEQDLCRAACVCKRFSELANDPILWKRLYMEVF 120
>gi|30089924 F-box only protein 11 isoform 2 [Homo sapiens]
Length = 686
Score = 42.4 bits (98), Expect = 6e-04
Identities = 19/47 (40%), Positives = 31/47 (65%)
Query: 6 ELPDSVLLEIFSYLPVRDRIRISRVCHRWKRLVDDRWLWRHVDLTLY 52
+LPD V+L+IFSYL +D R + VC R+ L +D LW+ + + ++
Sbjct: 74 KLPDEVVLKIFSYLLEQDLCRAACVCKRFSELANDPILWKRLYMEVF 120
>gi|30089922 F-box only protein 11 isoform 3 [Homo sapiens]
Length = 585
Score = 42.4 bits (98), Expect = 6e-04
Identities = 19/47 (40%), Positives = 31/47 (65%)
Query: 6 ELPDSVLLEIFSYLPVRDRIRISRVCHRWKRLVDDRWLWRHVDLTLY 52
+LPD V+L+IFSYL +D R + VC R+ L +D LW+ + + ++
Sbjct: 74 KLPDEVVLKIFSYLLEQDLCRAACVCKRFSELANDPILWKRLYMEVF 120
>gi|16306580 F-box and leucine-rich repeat protein 11 [Homo sapiens]
Length = 1162
Score = 41.2 bits (95), Expect = 0.001
Identities = 54/212 (25%), Positives = 84/212 (39%), Gaps = 30/212 (14%)
Query: 11 VLLEIFSYLPVRDRIRISRVCHRWKRLVDDRWLWRHVDLT-LYTMRPKVMWHLLRRYMAS 69
V + +F YL R+ RVC W + D+ LW +DL+ + P+ + +++R S
Sbjct: 897 VWMSVFRYLSRRELCECMRVCKTWYKWCCDKRLWTKIDLSRCKAIVPQALSGIIKRQPVS 956
Query: 70 RLHSLRMGGYLFSGSQAPQLSPALLRALGQKCPNLKRLCLHVADLSMVPITSLPS--TLR 127
S +S L L + P LK L L S V S S LR
Sbjct: 957 LDLSW------------TNISKKQLTWLVNRLPGLKDLLLAGCSWSAVSALSTSSCPLLR 1004
Query: 128 TLELHSCEISMAWLHKQQDPTVLPLLECIVLDRVPAFRDEHLQGLTRFRALRSLVLGGTY 187
TL+L W +DP + LL D+ L+ +T FR L G
Sbjct: 1005 TLDLR-------WAVGIKDPQIRDLL-TPPADKPGQDNRSKLRNMTDFR------LAG-L 1049
Query: 188 RVTETGLDAGLQELSYLQRLEVLGCTLSADST 219
+T+ L ++ + L RL++ C+ D +
Sbjct: 1050 DITDATLRLIIRHMPLLSRLDLSHCSHLTDQS 1081
>gi|229576894 F-box and WD repeat domain containing 12 isoform 2
[Homo sapiens]
Length = 394
Score = 40.8 bits (94), Expect = 0.002
Identities = 17/45 (37%), Positives = 27/45 (60%)
Query: 5 VELPDSVLLEIFSYLPVRDRIRISRVCHRWKRLVDDRWLWRHVDL 49
+ LPD L IFS+L + +++S+V W R+ D +LWR + L
Sbjct: 3 IRLPDLALKRIFSFLDLFGLLQVSQVNKHWNRIADSDYLWRSLSL 47
>gi|229576873 F-box and WD repeat domain containing 12 isoform 1
[Homo sapiens]
Length = 464
Score = 40.8 bits (94), Expect = 0.002
Identities = 17/45 (37%), Positives = 27/45 (60%)
Query: 5 VELPDSVLLEIFSYLPVRDRIRISRVCHRWKRLVDDRWLWRHVDL 49
+ LPD L IFS+L + +++S+V W R+ D +LWR + L
Sbjct: 3 IRLPDLALKRIFSFLDLFGLLQVSQVNKHWNRIADSDYLWRSLSL 47
>gi|54112382 F-box and leucine-rich repeat protein 10 isoform a [Homo
sapiens]
Length = 1336
Score = 40.8 bits (94), Expect = 0.002
Identities = 56/227 (24%), Positives = 93/227 (40%), Gaps = 35/227 (15%)
Query: 11 VLLEIFSYLPVRDRIRISRVCHRWKRLVDDRWLWRHVDLT-LYTMRPKVMWHLLRRYMAS 69
V + +FSYL +D RVC W R D+ LW +DL ++ P ++ ++RR S
Sbjct: 1069 VWMAVFSYLSHQDLCVCMRVCRTWNRWCCDKRLWTRIDLNHCKSITPLMLSGIIRRQPVS 1128
Query: 70 RLHSLRMGGYLFSGSQAPQLSPALLRALGQKCPNLKRLCLHVADLSMVPITSLPST---- 125
S +S L L + P L+ L L + S + +++L S+
Sbjct: 1129 LDLSW------------TNISKKQLSWLINRLPGLRDLVL--SGCSWIAVSALCSSSCPL 1174
Query: 126 LRTLELHSCEISMAWLHKQQDPTVLPLLECIVLDRVPAFRDEHLQGLTRFRALRSLVLGG 185
LRTL++ W+ +D + LL D P D ++ R + L L G
Sbjct: 1175 LRTLDVQ-------WVEGLKDAQMRDLLS-PPTDNRPGQMDNR----SKLRNIVELRLAG 1222
Query: 186 TYRVTETGLDAGLQELSYLQRLEVLGCTLSADST---LLAISRHLRD 229
+T+ L ++ + L +L + C D + L A+ RD
Sbjct: 1223 -LDITDASLRLIIRHMPLLSKLHLSYCNHVTDQSINLLTAVGTTTRD 1268
>gi|54112380 F-box and leucine-rich repeat protein 10 isoform b [Homo
sapiens]
Length = 1265
Score = 40.8 bits (94), Expect = 0.002
Identities = 56/227 (24%), Positives = 93/227 (40%), Gaps = 35/227 (15%)
Query: 11 VLLEIFSYLPVRDRIRISRVCHRWKRLVDDRWLWRHVDLT-LYTMRPKVMWHLLRRYMAS 69
V + +FSYL +D RVC W R D+ LW +DL ++ P ++ ++RR S
Sbjct: 1000 VWMAVFSYLSHQDLCVCMRVCRTWNRWCCDKRLWTRIDLNHCKSITPLMLSGIIRRQPVS 1059
Query: 70 RLHSLRMGGYLFSGSQAPQLSPALLRALGQKCPNLKRLCLHVADLSMVPITSLPST---- 125
S +S L L + P L+ L L + S + +++L S+
Sbjct: 1060 LDLSW------------TNISKKQLSWLINRLPGLRDLVL--SGCSWIAVSALCSSSCPL 1105
Query: 126 LRTLELHSCEISMAWLHKQQDPTVLPLLECIVLDRVPAFRDEHLQGLTRFRALRSLVLGG 185
LRTL++ W+ +D + LL D P D ++ R + L L G
Sbjct: 1106 LRTLDVQ-------WVEGLKDAQMRDLLS-PPTDNRPGQMDNR----SKLRNIVELRLAG 1153
Query: 186 TYRVTETGLDAGLQELSYLQRLEVLGCTLSADST---LLAISRHLRD 229
+T+ L ++ + L +L + C D + L A+ RD
Sbjct: 1154 -LDITDASLRLIIRHMPLLSKLHLSYCNHVTDQSINLLTAVGTTTRD 1199
>gi|161333854 F-box and leucine-rich repeat protein 13 isoform 2
[Homo sapiens]
Length = 690
Score = 40.4 bits (93), Expect = 0.002
Identities = 40/163 (24%), Positives = 71/163 (43%), Gaps = 40/163 (24%)
Query: 84 SQAPQLSPALLRALGQKCPNLK----RLCLHVADLSMVPITSLPSTLRTLELHSCEISMA 139
S +LS A + L ++CPNL R C H+ + I ++ S L +++L +IS
Sbjct: 487 SNCVRLSDASVMKLSERCPNLNYLSLRNCEHLTAQGIGYIVNIFS-LVSIDLSGTDIS-- 543
Query: 140 WLHKQQDPTVLPLLECIVLDRVPAFRDEHLQGLTRFRALRSLVLGGTYRVTETGL---DA 196
+E L L+R + L+ L + YR+T+ G+ D+
Sbjct: 544 --------------------------NEGLNVLSRHKKLKELSVSECYRITDDGIQITDS 577
Query: 197 GLQELS----YLQRLEVLGCTLSADSTLLAISRHLRDVRKIRL 235
++ LS YL L++ GC L D L + + +R +++
Sbjct: 578 AMEMLSAKCHYLHILDISGCVLLTDQILEDLQIGCKQLRILKM 620
Score = 38.9 bits (89), Expect = 0.006
Identities = 41/162 (25%), Positives = 70/162 (43%), Gaps = 30/162 (18%)
Query: 7 LPDSVLLEIFSYLPVRDRIRISRVCHRWKRLVDDRWLWRHVDLTLY--TMRPKVMWHLLR 64
LP+ +L+IF YL ++D I +V H W + LW +D + + K + L+
Sbjct: 158 LPERAILQIFFYLSLKDVIICGQVNHAWMLMTQLNSLWNAIDFSSVKNVIPDKYIVSTLQ 217
Query: 65 RYMASRLHSLRMG--GYL-----------------FSGSQAPQLSPALLRALGQKCPNLK 105
R+ RL+ LR+ G L + S P + +R + + CP +
Sbjct: 218 RW---RLNVLRLNFRGCLLRPKTFRSVSHCRNLQELNVSDCPTFTDESMRHISEGCPGV- 273
Query: 106 RLCLHVADLSMVPITSLPSTLRTLELHSCE-ISMAWLHKQQD 146
LCL +LS IT+ L H+ + +S+A+ + D
Sbjct: 274 -LCL---NLSNTTITNRTMRLLPRHFHNLQNLSLAYCRRFTD 311
>gi|23397500 F-box protein 39 [Homo sapiens]
Length = 442
Score = 39.3 bits (90), Expect = 0.005
Identities = 19/50 (38%), Positives = 30/50 (60%), Gaps = 1/50 (2%)
Query: 7 LPDSVLLEIFSYLPVRDRIRISRVCHRWKRLVDDRWLWRHVDLTLYTMRP 56
LPD L +F +L RDR R + VC +W +++ LWR+ +T ++ RP
Sbjct: 19 LPDLCLCRVFWWLGDRDRSRAALVCRKWNQMMYSAELWRYRTIT-FSGRP 67
>gi|8922188 F-box only protein 6 [Homo sapiens]
Length = 293
Score = 39.3 bits (90), Expect = 0.005
Identities = 17/41 (41%), Positives = 28/41 (68%), Gaps = 1/41 (2%)
Query: 6 ELPDSVLLEIFSYLPVRDRIRISR-VCHRWKRLVDDRWLWR 45
ELP+++LLE+F+++P R + R VC W+ L+D LW+
Sbjct: 15 ELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLMTLWK 55
>gi|16306574 F-box and leucine-rich repeat protein 5 isoform 2 [Homo
sapiens]
Length = 565
Score = 39.3 bits (90), Expect = 0.005
Identities = 17/44 (38%), Positives = 26/44 (59%)
Query: 4 LVELPDSVLLEIFSYLPVRDRIRISRVCHRWKRLVDDRWLWRHV 47
+ LP V+L IFSYL ++ R S+V +W +L LW+H+
Sbjct: 79 ITHLPPEVMLSIFSYLNPQELCRCSQVSMKWSQLTKTGSLWKHL 122
>gi|16306572 F-box and leucine-rich repeat protein 5 isoform 1 [Homo
sapiens]
Length = 691
Score = 39.3 bits (90), Expect = 0.005
Identities = 17/44 (38%), Positives = 26/44 (59%)
Query: 4 LVELPDSVLLEIFSYLPVRDRIRISRVCHRWKRLVDDRWLWRHV 47
+ LP V+L IFSYL ++ R S+V +W +L LW+H+
Sbjct: 205 ITHLPPEVMLSIFSYLNPQELCRCSQVSMKWSQLTKTGSLWKHL 248
>gi|15812198 F-box only protein 2 [Homo sapiens]
Length = 296
Score = 39.3 bits (90), Expect = 0.005
Identities = 20/44 (45%), Positives = 27/44 (61%), Gaps = 1/44 (2%)
Query: 2 ATLVELPDSVLLEIFSYLPVRDRIRISR-VCHRWKRLVDDRWLW 44
A L ELP+ +LL + + LP + ++ R VC RWK LVD LW
Sbjct: 45 AYLDELPEPLLLRVLAALPAAELVQACRLVCLRWKELVDGAPLW 88
>gi|161333852 F-box and leucine-rich repeat protein 13 isoform 1
[Homo sapiens]
Length = 735
Score = 38.9 bits (89), Expect = 0.006
Identities = 41/162 (25%), Positives = 70/162 (43%), Gaps = 30/162 (18%)
Query: 7 LPDSVLLEIFSYLPVRDRIRISRVCHRWKRLVDDRWLWRHVDLTLY--TMRPKVMWHLLR 64
LP+ +L+IF YL ++D I +V H W + LW +D + + K + L+
Sbjct: 158 LPERAILQIFFYLSLKDVIICGQVNHAWMLMTQLNSLWNAIDFSSVKNVIPDKYIVSTLQ 217
Query: 65 RYMASRLHSLRMG--GYL-----------------FSGSQAPQLSPALLRALGQKCPNLK 105
R+ RL+ LR+ G L + S P + +R + + CP +
Sbjct: 218 RW---RLNVLRLNFRGCLLRPKTFRSVSHCRNLQELNVSDCPTFTDESMRHISEGCPGV- 273
Query: 106 RLCLHVADLSMVPITSLPSTLRTLELHSCE-ISMAWLHKQQD 146
LCL +LS IT+ L H+ + +S+A+ + D
Sbjct: 274 -LCL---NLSNTTITNRTMRLLPRHFHNLQNLSLAYCRRFTD 311
Score = 34.7 bits (78), Expect = 0.12
Identities = 44/180 (24%), Positives = 79/180 (43%), Gaps = 29/180 (16%)
Query: 84 SQAPQLSPALLRALGQKCPNLKRL----CLHVADLSMVPITSLPSTLRTLELHSCEISMA 139
S +LS A + L ++CPNL L C H+ + I ++ S L +++L +IS
Sbjct: 487 SNCVRLSDASVMKLSERCPNLNYLSLRNCEHLTAQGIGYIVNIFS-LVSIDLSGTDISNE 545
Query: 140 WLH---KQQDPTVLPLLEC--IVLDRVPAFRD-----EHL-------------QGLTRFR 176
L+ + + L + EC I D + AF EHL + L +
Sbjct: 546 GLNVLSRHKKLKELSVSECYRITDDGIQAFCKSSLILEHLDVSYCSQLSDMIIKALAIYC 605
Query: 177 A-LRSLVLGGTYRVTETGLDAGLQELSYLQRLEVLGCTLSADSTLLAISRHLRDVRKIRL 235
L SL + G ++T++ ++ + YL L++ GC L D L + + +R +++
Sbjct: 606 INLTSLSIAGCPKITDSAMEMLSAKCHYLHILDISGCVLLTDQILEDLQIGCKQLRILKM 665
>gi|124248558 F-box and WD-40 domain protein 9 [Homo sapiens]
Length = 458
Score = 38.9 bits (89), Expect = 0.006
Identities = 21/43 (48%), Positives = 26/43 (60%), Gaps = 1/43 (2%)
Query: 4 LVELPDSVLLEIFSYLPVRDRIRI-SRVCHRWKRLVDDRWLWR 45
L+ LP +LLEI SYL R + + SRVCH + LV D WR
Sbjct: 79 LLSLPPELLLEICSYLDARLVLHVLSRVCHALRDLVSDHVTWR 121
>gi|83035136 F-box protein 31 [Homo sapiens]
Length = 539
Score = 38.5 bits (88), Expect = 0.008
Identities = 16/43 (37%), Positives = 30/43 (69%)
Query: 3 TLVELPDSVLLEIFSYLPVRDRIRISRVCHRWKRLVDDRWLWR 45
+L+ELP +L+EIF+ LP D +++VC +++R++ +WR
Sbjct: 66 SLLELPPELLVEIFASLPGTDLPSLAQVCTKFRRILHTDTIWR 108
>gi|16306584 F-box and leucine-rich repeat protein 3 [Homo
sapiens]
Length = 428
Score = 38.5 bits (88), Expect = 0.008
Identities = 16/45 (35%), Positives = 25/45 (55%)
Query: 7 LPDSVLLEIFSYLPVRDRIRISRVCHRWKRLVDDRWLWRHVDLTL 51
L ++L++F YLP+ DR S+VC W ++ LWR + L
Sbjct: 39 LLQDIILQVFKYLPLLDRAHASQVCRNWNQVFHMPDLWRCFEFEL 83
>gi|34878749 F-box protein 44 isoform 2 [Homo sapiens]
Length = 224
Score = 38.5 bits (88), Expect = 0.008
Identities = 17/41 (41%), Positives = 28/41 (68%), Gaps = 1/41 (2%)
Query: 6 ELPDSVLLEIFSYLPVRDRIRISR-VCHRWKRLVDDRWLWR 45
ELP+++LLE+F+++P R + R VC W+ L+D LW+
Sbjct: 8 ELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLVTLWK 48
>gi|34878735 F-box protein 44 isoform 1 [Homo sapiens]
Length = 255
Score = 38.5 bits (88), Expect = 0.008
Identities = 17/41 (41%), Positives = 28/41 (68%), Gaps = 1/41 (2%)
Query: 6 ELPDSVLLEIFSYLPVRDRIRISR-VCHRWKRLVDDRWLWR 45
ELP+++LLE+F+++P R + R VC W+ L+D LW+
Sbjct: 8 ELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLVTLWK 48
>gi|34878753 F-box protein 44 isoform 2 [Homo sapiens]
Length = 224
Score = 38.5 bits (88), Expect = 0.008
Identities = 17/41 (41%), Positives = 28/41 (68%), Gaps = 1/41 (2%)
Query: 6 ELPDSVLLEIFSYLPVRDRIRISR-VCHRWKRLVDDRWLWR 45
ELP+++LLE+F+++P R + R VC W+ L+D LW+
Sbjct: 8 ELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLVTLWK 48
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.326 0.139 0.438
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,776,453
Number of Sequences: 37866
Number of extensions: 578392
Number of successful extensions: 1846
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 55
Number of HSP's successfully gapped in prelim test: 35
Number of HSP's that attempted gapping in prelim test: 1730
Number of HSP's gapped (non-prelim): 121
length of query: 326
length of database: 18,247,518
effective HSP length: 103
effective length of query: 223
effective length of database: 14,347,320
effective search space: 3199452360
effective search space used: 3199452360
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.