BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|88501734 integrin alpha M isoform 2 precursor [Homo sapiens] (1152 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|88501734 integrin alpha M isoform 2 precursor [Homo sapiens] 2296 0.0 gi|224831239 integrin alpha M isoform 1 precursor [Homo sapiens] 2292 0.0 gi|34452173 integrin alpha X precursor [Homo sapiens] 1358 0.0 gi|62548866 integrin, alpha D precursor [Homo sapiens] 1329 0.0 gi|167466215 integrin alpha L isoform a precursor [Homo sapiens] 577 e-164 gi|167466217 integrin alpha L isoform b precursor [Homo sapiens] 473 e-133 gi|148728188 integrin, alpha E precursor [Homo sapiens] 417 e-116 gi|239751058 PREDICTED: hypothetical protein XP_002347690 [Homo ... 406 e-113 gi|31657142 integrin, alpha 1 precursor [Homo sapiens] 397 e-110 gi|52485853 integrin, alpha 11 precursor [Homo sapiens] 380 e-105 gi|38569398 integrin, alpha 10 precursor [Homo sapiens] 380 e-105 gi|116295258 integrin alpha 2 precursor [Homo sapiens] 373 e-103 gi|52485941 integrin, alpha 9 precursor [Homo sapiens] 213 1e-54 gi|67191027 integrin alpha 4 precursor [Homo sapiens] 212 2e-54 gi|223468595 integrin alpha-V isoform 2 [Homo sapiens] 168 2e-41 gi|4504763 integrin alpha-V isoform 1 precursor [Homo sapiens] 168 2e-41 gi|56237029 integrin alpha 5 precursor [Homo sapiens] 168 3e-41 gi|223468597 integrin alpha-V isoform 3 precursor [Homo sapiens] 164 3e-40 gi|4504747 integrin alpha 3 isoform a precursor [Homo sapiens] 164 6e-40 gi|6006011 integrin alpha 3 isoform b precursor [Homo sapiens] 161 4e-39 gi|119395742 integrin alpha chain, alpha 6 isoform b precursor [... 155 2e-37 gi|119395740 integrin alpha chain, alpha 6 isoform a precursor [... 153 1e-36 gi|49170034 integrin, alpha 8 [Homo sapiens] 152 2e-36 gi|88758615 integrin alpha 2b preproprotein [Homo sapiens] 145 2e-34 gi|222418611 integrin alpha 7 isoform 2 precursor [Homo sapiens] 137 6e-32 gi|222418615 integrin alpha 7 isoform 3 [Homo sapiens] 131 4e-30 gi|222418613 integrin alpha 7 isoform 1 precursor [Homo sapiens] 131 4e-30 gi|4505111 matrilin 1, cartilage matrix protein [Homo sapiens] 94 1e-18 gi|55743096 collagen, type XIV, alpha 1 [Homo sapiens] 91 6e-18 gi|62548862 matrilin 2 isoform b precursor [Homo sapiens] 87 1e-16 >gi|88501734 integrin alpha M isoform 2 precursor [Homo sapiens] Length = 1152 Score = 2296 bits (5951), Expect = 0.0 Identities = 1152/1152 (100%), Positives = 1152/1152 (100%) Query: 1 MALRVLLLTALTLCHGFNLDTENAMTFQENARGFGQSVVQLQGSRVVVGAPQEIVAANQR 60 MALRVLLLTALTLCHGFNLDTENAMTFQENARGFGQSVVQLQGSRVVVGAPQEIVAANQR Sbjct: 1 MALRVLLLTALTLCHGFNLDTENAMTFQENARGFGQSVVQLQGSRVVVGAPQEIVAANQR 60 Query: 61 GSLYQCDYSTGSCEPIRLQVPVEAVNMSLGLSLAATTSPPQLLACGPTVHQTCSENTYVK 120 GSLYQCDYSTGSCEPIRLQVPVEAVNMSLGLSLAATTSPPQLLACGPTVHQTCSENTYVK Sbjct: 61 GSLYQCDYSTGSCEPIRLQVPVEAVNMSLGLSLAATTSPPQLLACGPTVHQTCSENTYVK 120 Query: 121 GLCFLFGSNLRQQPQKFPEALRGCPQEDSDIAFLIDGSGSIIPHDFRRMKEFVSTVMEQL 180 GLCFLFGSNLRQQPQKFPEALRGCPQEDSDIAFLIDGSGSIIPHDFRRMKEFVSTVMEQL Sbjct: 121 GLCFLFGSNLRQQPQKFPEALRGCPQEDSDIAFLIDGSGSIIPHDFRRMKEFVSTVMEQL 180 Query: 181 KKSKTLFSLMQYSEEFRIHFTFKEFQNNPNPRSLVKPITQLLGRTHTATGIRKVVRELFN 240 KKSKTLFSLMQYSEEFRIHFTFKEFQNNPNPRSLVKPITQLLGRTHTATGIRKVVRELFN Sbjct: 181 KKSKTLFSLMQYSEEFRIHFTFKEFQNNPNPRSLVKPITQLLGRTHTATGIRKVVRELFN 240 Query: 241 ITNGARKNAFKILVVITDGEKFGDPLGYEDVIPEADREGVIRYVIGVGDAFRSEKSRQEL 300 ITNGARKNAFKILVVITDGEKFGDPLGYEDVIPEADREGVIRYVIGVGDAFRSEKSRQEL Sbjct: 241 ITNGARKNAFKILVVITDGEKFGDPLGYEDVIPEADREGVIRYVIGVGDAFRSEKSRQEL 300 Query: 301 NTIASKPPRDHVFQVNNFEALKTIQNQLREKIFAIEGTQTGSSSSFEHEMSQEGFSAAIT 360 NTIASKPPRDHVFQVNNFEALKTIQNQLREKIFAIEGTQTGSSSSFEHEMSQEGFSAAIT Sbjct: 301 NTIASKPPRDHVFQVNNFEALKTIQNQLREKIFAIEGTQTGSSSSFEHEMSQEGFSAAIT 360 Query: 361 SNGPLLSTVGSYDWAGGVFLYTSKEKSTFINMTRVDSDMNDAYLGYAAAIILRNRVQSLV 420 SNGPLLSTVGSYDWAGGVFLYTSKEKSTFINMTRVDSDMNDAYLGYAAAIILRNRVQSLV Sbjct: 361 SNGPLLSTVGSYDWAGGVFLYTSKEKSTFINMTRVDSDMNDAYLGYAAAIILRNRVQSLV 420 Query: 421 LGAPRYQHIGLVAMFRQNTGMWESNANVKGTQIGAYFGASLCSVDVDSNGSTDLVLIGAP 480 LGAPRYQHIGLVAMFRQNTGMWESNANVKGTQIGAYFGASLCSVDVDSNGSTDLVLIGAP Sbjct: 421 LGAPRYQHIGLVAMFRQNTGMWESNANVKGTQIGAYFGASLCSVDVDSNGSTDLVLIGAP 480 Query: 481 HYYEQTRGGQVSVCPLPRGRARWQCDAVLYGEQGQPWGRFGAALTVLGDVNGDKLTDVAI 540 HYYEQTRGGQVSVCPLPRGRARWQCDAVLYGEQGQPWGRFGAALTVLGDVNGDKLTDVAI Sbjct: 481 HYYEQTRGGQVSVCPLPRGRARWQCDAVLYGEQGQPWGRFGAALTVLGDVNGDKLTDVAI 540 Query: 541 GAPGEEDNRGAVYLFHGTSGSGISPSHSQRIAGSKLSPRLQYFGQSLSGGQDLTMDGLVD 600 GAPGEEDNRGAVYLFHGTSGSGISPSHSQRIAGSKLSPRLQYFGQSLSGGQDLTMDGLVD Sbjct: 541 GAPGEEDNRGAVYLFHGTSGSGISPSHSQRIAGSKLSPRLQYFGQSLSGGQDLTMDGLVD 600 Query: 601 LTVGAQGHVLLLRSQPVLRVKAIMEFNPREVARNVFECNDQVVKGKEAGEVRVCLHVQKS 660 LTVGAQGHVLLLRSQPVLRVKAIMEFNPREVARNVFECNDQVVKGKEAGEVRVCLHVQKS Sbjct: 601 LTVGAQGHVLLLRSQPVLRVKAIMEFNPREVARNVFECNDQVVKGKEAGEVRVCLHVQKS 660 Query: 661 TRDRLREGQIQSVVTYDLALDSGRPHSRAVFNETKNSTRRQTQVLGLTQTCETLKLQLPN 720 TRDRLREGQIQSVVTYDLALDSGRPHSRAVFNETKNSTRRQTQVLGLTQTCETLKLQLPN Sbjct: 661 TRDRLREGQIQSVVTYDLALDSGRPHSRAVFNETKNSTRRQTQVLGLTQTCETLKLQLPN 720 Query: 721 CIEDPVSPIVLRLNFSLVGTPLSAFGNLRPVLAEDAQRLFTALFPFEKNCGNDNICQDDL 780 CIEDPVSPIVLRLNFSLVGTPLSAFGNLRPVLAEDAQRLFTALFPFEKNCGNDNICQDDL Sbjct: 721 CIEDPVSPIVLRLNFSLVGTPLSAFGNLRPVLAEDAQRLFTALFPFEKNCGNDNICQDDL 780 Query: 781 SITFSFMSLDCLVVGGPREFNVTVTVRNDGEDSYRTQVTFFFPLDLSYRKVSTLQNQRSQ 840 SITFSFMSLDCLVVGGPREFNVTVTVRNDGEDSYRTQVTFFFPLDLSYRKVSTLQNQRSQ Sbjct: 781 SITFSFMSLDCLVVGGPREFNVTVTVRNDGEDSYRTQVTFFFPLDLSYRKVSTLQNQRSQ 840 Query: 841 RSWRLACESASSTEVSGALKSTSCSINHPIFPENSEVTFNITFDVDSKASLGNKLLLKAN 900 RSWRLACESASSTEVSGALKSTSCSINHPIFPENSEVTFNITFDVDSKASLGNKLLLKAN Sbjct: 841 RSWRLACESASSTEVSGALKSTSCSINHPIFPENSEVTFNITFDVDSKASLGNKLLLKAN 900 Query: 901 VTSENNMPRTNKTEFQLELPVKYAVYMVVTSHGVSTKYLNFTASENTSRVMQHQYQVSNL 960 VTSENNMPRTNKTEFQLELPVKYAVYMVVTSHGVSTKYLNFTASENTSRVMQHQYQVSNL Sbjct: 901 VTSENNMPRTNKTEFQLELPVKYAVYMVVTSHGVSTKYLNFTASENTSRVMQHQYQVSNL 960 Query: 961 GQRSLPISLVFLVPVRLNQTVIWDRPQVTFSENLSSTCHTKERLPSHSDFLAELRKAPVV 1020 GQRSLPISLVFLVPVRLNQTVIWDRPQVTFSENLSSTCHTKERLPSHSDFLAELRKAPVV Sbjct: 961 GQRSLPISLVFLVPVRLNQTVIWDRPQVTFSENLSSTCHTKERLPSHSDFLAELRKAPVV 1020 Query: 1021 NCSIAVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYIKTSHNHLLIVSTAEILFNDSVFT 1080 NCSIAVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYIKTSHNHLLIVSTAEILFNDSVFT Sbjct: 1021 NCSIAVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYIKTSHNHLLIVSTAEILFNDSVFT 1080 Query: 1081 LLPGQGAFVRSQTETKVEPFEVPNPLPLIVGSSVGGLLLLALITAALYKLGFFKRQYKDM 1140 LLPGQGAFVRSQTETKVEPFEVPNPLPLIVGSSVGGLLLLALITAALYKLGFFKRQYKDM Sbjct: 1081 LLPGQGAFVRSQTETKVEPFEVPNPLPLIVGSSVGGLLLLALITAALYKLGFFKRQYKDM 1140 Query: 1141 MSEGGPPGAEPQ 1152 MSEGGPPGAEPQ Sbjct: 1141 MSEGGPPGAEPQ 1152 >gi|224831239 integrin alpha M isoform 1 precursor [Homo sapiens] Length = 1153 Score = 2292 bits (5939), Expect = 0.0 Identities = 1152/1153 (99%), Positives = 1152/1153 (99%), Gaps = 1/1153 (0%) Query: 1 MALRVLLLTALTLCHGFNLDTENAMTFQENARGFGQSVVQLQGSRVVVGAPQEIVAANQR 60 MALRVLLLTALTLCHGFNLDTENAMTFQENARGFGQSVVQLQGSRVVVGAPQEIVAANQR Sbjct: 1 MALRVLLLTALTLCHGFNLDTENAMTFQENARGFGQSVVQLQGSRVVVGAPQEIVAANQR 60 Query: 61 GSLYQCDYSTGSCEPIRLQVPVEAVNMSLGLSLAATTSPPQLLACGPTVHQTCSENTYVK 120 GSLYQCDYSTGSCEPIRLQVPVEAVNMSLGLSLAATTSPPQLLACGPTVHQTCSENTYVK Sbjct: 61 GSLYQCDYSTGSCEPIRLQVPVEAVNMSLGLSLAATTSPPQLLACGPTVHQTCSENTYVK 120 Query: 121 GLCFLFGSNLRQQPQKFPEALRGCPQEDSDIAFLIDGSGSIIPHDFRRMKEFVSTVMEQL 180 GLCFLFGSNLRQQPQKFPEALRGCPQEDSDIAFLIDGSGSIIPHDFRRMKEFVSTVMEQL Sbjct: 121 GLCFLFGSNLRQQPQKFPEALRGCPQEDSDIAFLIDGSGSIIPHDFRRMKEFVSTVMEQL 180 Query: 181 KKSKTLFSLMQYSEEFRIHFTFKEFQNNPNPRSLVKPITQLLGRTHTATGIRKVVRELFN 240 KKSKTLFSLMQYSEEFRIHFTFKEFQNNPNPRSLVKPITQLLGRTHTATGIRKVVRELFN Sbjct: 181 KKSKTLFSLMQYSEEFRIHFTFKEFQNNPNPRSLVKPITQLLGRTHTATGIRKVVRELFN 240 Query: 241 ITNGARKNAFKILVVITDGEKFGDPLGYEDVIPEADREGVIRYVIGVGDAFRSEKSRQEL 300 ITNGARKNAFKILVVITDGEKFGDPLGYEDVIPEADREGVIRYVIGVGDAFRSEKSRQEL Sbjct: 241 ITNGARKNAFKILVVITDGEKFGDPLGYEDVIPEADREGVIRYVIGVGDAFRSEKSRQEL 300 Query: 301 NTIASKPPRDHVFQVNNFEALKTIQNQLREKIFAIEGTQTGSSSSFEHEMSQEGFSAAIT 360 NTIASKPPRDHVFQVNNFEALKTIQNQLREKIFAIEGTQTGSSSSFEHEMSQEGFSAAIT Sbjct: 301 NTIASKPPRDHVFQVNNFEALKTIQNQLREKIFAIEGTQTGSSSSFEHEMSQEGFSAAIT 360 Query: 361 SNGPLLSTVGSYDWAGGVFLYTSKEKSTFINMTRVDSDMNDAYLGYAAAIILRNRVQSLV 420 SNGPLLSTVGSYDWAGGVFLYTSKEKSTFINMTRVDSDMNDAYLGYAAAIILRNRVQSLV Sbjct: 361 SNGPLLSTVGSYDWAGGVFLYTSKEKSTFINMTRVDSDMNDAYLGYAAAIILRNRVQSLV 420 Query: 421 LGAPRYQHIGLVAMFRQNTGMWESNANVKGTQIGAYFGASLCSVDVDSNGSTDLVLIGAP 480 LGAPRYQHIGLVAMFRQNTGMWESNANVKGTQIGAYFGASLCSVDVDSNGSTDLVLIGAP Sbjct: 421 LGAPRYQHIGLVAMFRQNTGMWESNANVKGTQIGAYFGASLCSVDVDSNGSTDLVLIGAP 480 Query: 481 HYYEQTRGGQVSVCPLPRG-RARWQCDAVLYGEQGQPWGRFGAALTVLGDVNGDKLTDVA 539 HYYEQTRGGQVSVCPLPRG RARWQCDAVLYGEQGQPWGRFGAALTVLGDVNGDKLTDVA Sbjct: 481 HYYEQTRGGQVSVCPLPRGQRARWQCDAVLYGEQGQPWGRFGAALTVLGDVNGDKLTDVA 540 Query: 540 IGAPGEEDNRGAVYLFHGTSGSGISPSHSQRIAGSKLSPRLQYFGQSLSGGQDLTMDGLV 599 IGAPGEEDNRGAVYLFHGTSGSGISPSHSQRIAGSKLSPRLQYFGQSLSGGQDLTMDGLV Sbjct: 541 IGAPGEEDNRGAVYLFHGTSGSGISPSHSQRIAGSKLSPRLQYFGQSLSGGQDLTMDGLV 600 Query: 600 DLTVGAQGHVLLLRSQPVLRVKAIMEFNPREVARNVFECNDQVVKGKEAGEVRVCLHVQK 659 DLTVGAQGHVLLLRSQPVLRVKAIMEFNPREVARNVFECNDQVVKGKEAGEVRVCLHVQK Sbjct: 601 DLTVGAQGHVLLLRSQPVLRVKAIMEFNPREVARNVFECNDQVVKGKEAGEVRVCLHVQK 660 Query: 660 STRDRLREGQIQSVVTYDLALDSGRPHSRAVFNETKNSTRRQTQVLGLTQTCETLKLQLP 719 STRDRLREGQIQSVVTYDLALDSGRPHSRAVFNETKNSTRRQTQVLGLTQTCETLKLQLP Sbjct: 661 STRDRLREGQIQSVVTYDLALDSGRPHSRAVFNETKNSTRRQTQVLGLTQTCETLKLQLP 720 Query: 720 NCIEDPVSPIVLRLNFSLVGTPLSAFGNLRPVLAEDAQRLFTALFPFEKNCGNDNICQDD 779 NCIEDPVSPIVLRLNFSLVGTPLSAFGNLRPVLAEDAQRLFTALFPFEKNCGNDNICQDD Sbjct: 721 NCIEDPVSPIVLRLNFSLVGTPLSAFGNLRPVLAEDAQRLFTALFPFEKNCGNDNICQDD 780 Query: 780 LSITFSFMSLDCLVVGGPREFNVTVTVRNDGEDSYRTQVTFFFPLDLSYRKVSTLQNQRS 839 LSITFSFMSLDCLVVGGPREFNVTVTVRNDGEDSYRTQVTFFFPLDLSYRKVSTLQNQRS Sbjct: 781 LSITFSFMSLDCLVVGGPREFNVTVTVRNDGEDSYRTQVTFFFPLDLSYRKVSTLQNQRS 840 Query: 840 QRSWRLACESASSTEVSGALKSTSCSINHPIFPENSEVTFNITFDVDSKASLGNKLLLKA 899 QRSWRLACESASSTEVSGALKSTSCSINHPIFPENSEVTFNITFDVDSKASLGNKLLLKA Sbjct: 841 QRSWRLACESASSTEVSGALKSTSCSINHPIFPENSEVTFNITFDVDSKASLGNKLLLKA 900 Query: 900 NVTSENNMPRTNKTEFQLELPVKYAVYMVVTSHGVSTKYLNFTASENTSRVMQHQYQVSN 959 NVTSENNMPRTNKTEFQLELPVKYAVYMVVTSHGVSTKYLNFTASENTSRVMQHQYQVSN Sbjct: 901 NVTSENNMPRTNKTEFQLELPVKYAVYMVVTSHGVSTKYLNFTASENTSRVMQHQYQVSN 960 Query: 960 LGQRSLPISLVFLVPVRLNQTVIWDRPQVTFSENLSSTCHTKERLPSHSDFLAELRKAPV 1019 LGQRSLPISLVFLVPVRLNQTVIWDRPQVTFSENLSSTCHTKERLPSHSDFLAELRKAPV Sbjct: 961 LGQRSLPISLVFLVPVRLNQTVIWDRPQVTFSENLSSTCHTKERLPSHSDFLAELRKAPV 1020 Query: 1020 VNCSIAVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYIKTSHNHLLIVSTAEILFNDSVF 1079 VNCSIAVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYIKTSHNHLLIVSTAEILFNDSVF Sbjct: 1021 VNCSIAVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYIKTSHNHLLIVSTAEILFNDSVF 1080 Query: 1080 TLLPGQGAFVRSQTETKVEPFEVPNPLPLIVGSSVGGLLLLALITAALYKLGFFKRQYKD 1139 TLLPGQGAFVRSQTETKVEPFEVPNPLPLIVGSSVGGLLLLALITAALYKLGFFKRQYKD Sbjct: 1081 TLLPGQGAFVRSQTETKVEPFEVPNPLPLIVGSSVGGLLLLALITAALYKLGFFKRQYKD 1140 Query: 1140 MMSEGGPPGAEPQ 1152 MMSEGGPPGAEPQ Sbjct: 1141 MMSEGGPPGAEPQ 1153 >gi|34452173 integrin alpha X precursor [Homo sapiens] Length = 1163 Score = 1358 bits (3515), Expect = 0.0 Identities = 701/1140 (61%), Positives = 839/1140 (73%), Gaps = 5/1140 (0%) Query: 5 VLLLTALTLCHGFNLDTENAMTFQENARGFGQSVVQLQGSRVVVGAPQEIVAANQRGSLY 64 +LL TAL GFNLDTE F+ ++ GFG SVVQ S VVVGAPQ+I AANQ G LY Sbjct: 8 LLLFTALATSLGFNLDTEELTAFRVDSAGFGDSVVQYANSWVVVGAPQKITAANQTGGLY 67 Query: 65 QCDYSTGSCEPIRLQVPVEAVNMSLGLSLAATTSPPQLLACGPTVHQTCSENTYVKGLCF 124 QC YSTG+CEPI LQVP EAVNMSLGLSLA+TTSP QLLACGPTVH C N Y+ GLCF Sbjct: 68 QCGYSTGACEPIGLQVPPEAVNMSLGLSLASTTSPSQLLACGPTVHHECGRNMYLTGLCF 127 Query: 125 LFGSNLRQQPQKFPEALRGCPQEDSDIAFLIDGSGSIIPHDFRRMKEFVSTVMEQLKKSK 184 L G Q Q+ P + + CP+++ DI FLIDGSGSI +F M FV V+ Q ++ Sbjct: 128 LLGPT--QLTQRLPVSRQECPRQEQDIVFLIDGSGSISSRNFATMMNFVRAVISQFQRPS 185 Query: 185 TLFSLMQYSEEFRIHFTFKEFQNNPNPRSLVKPITQLLGRTHTATGIRKVVRELFNITNG 244 T FSLMQ+S +F+ HFTF+EF+ + NP SL+ + QL G T+TAT I+ VV LF+ + G Sbjct: 186 TQFSLMQFSNKFQTHFTFEEFRRSSNPLSLLASVHQLQGFTYTATAIQNVVHRLFHASYG 245 Query: 245 ARKNAFKILVVITDGEKFGDPLGYEDVIPEADREGVIRYVIGVGDAFRSEKSRQELNTIA 304 AR++A KIL+VITDG+K GD L Y+DVIP AD G+IRY IGVG AF++ S +ELN IA Sbjct: 246 ARRDAAKILIVITDGKKEGDSLDYKDVIPMADAAGIIRYAIGVGLAFQNRNSWKELNDIA 305 Query: 305 SKPPRDHVFQVNNFEALKTIQNQLREKIFAIEGTQTGSSSSFEHEMSQEGFSAAITSNGP 364 SKP ++H+F+V +F+ALK IQNQL+EKIFAIEGT+T SSSSFE EM+QEGFSA T +GP Sbjct: 306 SKPSQEHIFKVEDFDALKDIQNQLKEKIFAIEGTETTSSSSFELEMAQEGFSAVFTPDGP 365 Query: 365 LLSTVGSYDWAGGVFLYTSKEKSTFINMTRVDSDMNDAYLGYAAAIILRNRVQSLVLGAP 424 +L VGS+ W+GG FLY TFINM++ + DM D+YLGY+ + L VQSLVLGAP Sbjct: 366 VLGAVGSFTWSGGAFLYPPNMSPTFINMSQENVDMRDSYLGYSTELALWKGVQSLVLGAP 425 Query: 425 RYQHIGLVAMFRQNTGMWESNANVKGTQIGAYFGASLCSVDVDSNGSTDLVLIGAPHYYE 484 RYQH G +F Q + W A V GTQIG+YFGASLCSVDVDS+GSTDLVLIGAPHYYE Sbjct: 426 RYQHTGKAVIFTQVSRQWRMKAEVTGTQIGSYFGASLCSVDVDSDGSTDLVLIGAPHYYE 485 Query: 485 QTRGGQVSVCPLPRGRARWQCDAVLYGEQGQPWGRFGAALTVLGDVNGDKLTDVAIGAPG 544 QTRGGQVSVCPLPRG RW CDAVLYGEQG PWGRFGAALTVLGDVNGDKLTDV IGAPG Sbjct: 486 QTRGGQVSVCPLPRGWRRWWCDAVLYGEQGHPWGRFGAALTVLGDVNGDKLTDVVIGAPG 545 Query: 545 EEDNRGAVYLFHGTSGSGISPSHSQRIAGSKLSPRLQYFGQSLSGGQDLTMDGLVDLTVG 604 EE+NRGAVYLFHG G ISPSHSQRIAGS+LS RLQYFGQ+LSGGQDLT DGLVDL VG Sbjct: 546 EEENRGAVYLFHGVLGPSISPSHSQRIAGSQLSSRLQYFGQALSGGQDLTQDGLVDLAVG 605 Query: 605 AQGHVLLLRSQPVLRVKAIMEFNPREVARNVFECNDQVVKGKEAGEVRVCLHVQKSTRDR 664 A+G VLLLR++PVL V M+F P E+ R+ FEC +QVV + + +CL++ K +++ Sbjct: 606 ARGQVLLLRTRPVLWVGVSMQFIPAEIPRSAFECREQVVSEQTLVQSNICLYIDKRSKNL 665 Query: 665 LREGQIQSVVTYDLALDSGRPHSRAVFNETKNSTRRQTQVLGLTQTCETLKLQLPNCIED 724 L +QS VT DLALD GR RA F ETKN + + +VLGL CE L LP+C+ED Sbjct: 666 LGSRDLQSSVTLDLALDPGRLSPRATFQETKNRSLSRVRVLGLKAHCENFNLLLPSCVED 725 Query: 725 PVSPIVLRLNFSLVGTPLSAFGNLRPVLAEDAQRLFTALFPFEKNCGNDNICQDDLSITF 784 V+PI LRLNF+LVG PL AF NLRP+LA DAQR FTA PFEKNCG D+ICQD+L I+F Sbjct: 726 SVTPITLRLNFTLVGKPLLAFRNLRPMLAADAQRYFTASLPFEKNCGADHICQDNLGISF 785 Query: 785 SFMSLDCLVVGGPREFNVTVTVRNDGEDSYRTQVTFFFPLDLSYRKVSTLQNQRSQRSWR 844 SF L L+VG E N V V NDGEDSY T +TF P LSYR V+ Q Q RS Sbjct: 786 SFPGLKSLLVGSNLELNAEVMVWNDGEDSYGTTITFSHPAGLSYRYVAEGQKQGQLRSLH 845 Query: 845 LACESASSTEVSGALKSTSCSINHPIFPENSEVTFNITFDVDSKASLGNKLLLKANVTSE 904 L C+SA S STSC INH IF +++TF TFDV KA LG++LLL ANV+SE Sbjct: 846 LTCDSAPVG--SQGTWSTSCRINHLIFRGGAQITFLATFDVSPKAVLGDRLLLTANVSSE 903 Query: 905 NNMPRTNKTEFQLELPVKYAVYMVVTSHGVSTKYLNFTAS-ENTSRVMQHQYQVSNLGQR 963 NN PRT+KT FQLELPVKYAVY VV+SH TKYLNF+ S E S V H+YQV+NLGQR Sbjct: 904 NNTPRTSKTTFQLELPVKYAVYTVVSSHEQFTKYLNFSESEEKESHVAMHRYQVNNLGQR 963 Query: 964 SLPISLVFLVPVRLNQTVIWDRPQVTFSENLSSTCHTKERLPSHSDFLAELRKAPVVNCS 1023 LP+S+ F VPV LNQ +W +V+ +N S C +++ P SDFLA ++K PV++CS Sbjct: 964 DLPVSINFWVPVELNQEAVWMDVEVSHPQNPSLRCSSEKIAPPASDFLAHIQKNPVLDCS 1023 Query: 1024 IAVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYIKTSHNHLLIVSTAEILFNDSVFTLLP 1083 IA C R +CD+P F +QEE + TLKGNLSF W + + +VS AEI F+ SV++ LP Sbjct: 1024 IAGCLRFRCDVPSFSVQEELDFTLKGNLSFGWVRQILQKKVSVVSVAEITFDTSVYSQLP 1083 Query: 1084 GQGAFVRSQTETKVEPFEVPNPLPLIVGSSVGGLLLLALITAALYKLGFFKRQYKDMMSE 1143 GQ AF+R+QT T +E ++V NP PLIVGSS+GGLLLLALITA LYK+GFFKRQYK+MM E Sbjct: 1084 GQEAFMRAQTTTVLEKYKVHNPTPLIVGSSIGGLLLLALITAVLYKVGFFKRQYKEMMEE 1143 >gi|62548866 integrin, alpha D precursor [Homo sapiens] Length = 1161 Score = 1329 bits (3440), Expect = 0.0 Identities = 683/1140 (59%), Positives = 845/1140 (74%), Gaps = 8/1140 (0%) Query: 5 VLLLTALTLCHGFNLDTENAMTFQENARGFGQSVVQLQGSRVVVGAPQEIVAANQRGSLY 64 VLLL+ L HGFNLD E FQE+A GFGQSVVQ GSR+VVGAP E+VAANQ G LY Sbjct: 6 VLLLSVLASYHGFNLDVEEPTIFQEDAGGFGQSVVQFGGSRLVVGAPLEVVAANQTGRLY 65 Query: 65 QCDYSTGSCEPIRLQVPVEAVNMSLGLSLAATTSPPQLLACGPTVHQTCSENTYVKGLCF 124 C +TG C+PI L + EAVNMSLGL+LAA+T+ +LLACGPT+H+ C EN+Y KG C Sbjct: 66 DCAAATGMCQPIPLHIRPEAVNMSLGLTLAASTNGSRLLACGPTLHRVCGENSYSKGSCL 125 Query: 125 LFGSNLRQQPQKFPEALRGCPQEDSDIAFLIDGSGSIIPHDFRRMKEFVSTVMEQLKKSK 184 L GS + Q P+A CP ++ DI FLIDGSGSI +DF +MK FV VM Q + + Sbjct: 126 LLGSRW-EIIQTVPDATPECPHQEMDIVFLIDGSGSIDQNDFNQMKGFVQAVMGQFEGTD 184 Query: 185 TLFSLMQYSEEFRIHFTFKEFQNNPNPRSLVKPITQLLGRTHTATGIRKVVRELFNITNG 244 TLF+LMQYS +IHFTF +F+ +P+ +SLV PI QL G T TATGI VV +LF+ NG Sbjct: 185 TLFALMQYSNLLKIHFTFTQFRTSPSQQSLVDPIVQLKGLTFTATGILTVVTQLFHHKNG 244 Query: 245 ARKNAFKILVVITDGEKFGDPLGYEDVIPEADREGVIRYVIGVGDAFRSEKSRQELNTIA 304 ARK+A KIL+VITDG+K+ DPL Y DVIP+A++ G+IRY IGVG AF+ +RQELNTI+ Sbjct: 245 ARKSAKKILIVITDGQKYKDPLEYSDVIPQAEKAGIIRYAIGVGHAFQGPTARQELNTIS 304 Query: 305 SKPPRDHVFQVNNFEALKTIQNQLREKIFAIEGTQTGSSSSFEHEMSQEGFSAAITSNGP 364 S PP+DHVF+V+NF AL +IQ QL+EKI+A+EGTQ+ +SSSF+HEMSQEGFS A+T +G Sbjct: 305 SAPPQDHVFKVDNFAALGSIQKQLQEKIYAVEGTQSRASSSFQHEMSQEGFSTALTMDGL 364 Query: 365 LLSTVGSYDWAGGVFLYTSKEKSTFINMTRVDSDMNDAYLGYAAAIILRNRVQSLVLGAP 424 L VGS+ W+GG FLY TFINM++ + DM D+YLGY+ + L VQ+LVLGAP Sbjct: 365 FLGAVGSFSWSGGAFLYPPNMSPTFINMSQENVDMRDSYLGYSTELALWKGVQNLVLGAP 424 Query: 425 RYQHIGLVAMFRQNTGMWESNANVKGTQIGAYFGASLCSVDVDSNGSTDLVLIGAPHYYE 484 RYQH G +F Q + W A V GTQIG+YFGASLCSVDVDS+GSTDL+LIGAPHYYE Sbjct: 425 RYQHTGKAVIFTQVSRQWRKKAEVTGTQIGSYFGASLCSVDVDSDGSTDLILIGAPHYYE 484 Query: 485 QTRGGQVSVCPLPRGRARWQCDAVLYGEQGQPWGRFGAALTVLGDVNGDKLTDVAIGAPG 544 QTRGGQVSVCPLPRGR +WQCDAVL GEQG PWGRFGAALTVLGDVN DKL DVAIGAPG Sbjct: 485 QTRGGQVSVCPLPRGRVQWQCDAVLRGEQGHPWGRFGAALTVLGDVNEDKLIDVAIGAPG 544 Query: 545 EEDNRGAVYLFHGTSGSGISPSHSQRIAGSKLSPRLQYFGQSLSGGQDLTMDGLVDLTVG 604 E++NRGAVYLFHG S SGISPSHSQRIA S+LSPRLQYFGQ+LSGGQDLT DGL+DL VG Sbjct: 545 EQENRGAVYLFHGASESGISPSHSQRIASSQLSPRLQYFGQALSGGQDLTQDGLMDLAVG 604 Query: 605 AQGHVLLLRSQPVLRVKAIMEFNPREVARNVFECNDQVVKGKEAGEVRVCLHVQKSTRDR 664 A+G VLLLRS PVL+V M F+P EVA+ V+ C ++ EAG+ VCL +QKS+ D+ Sbjct: 605 ARGQVLLLRSLPVLKVGVAMRFSPVEVAKAVYRCWEEKPSALEAGDATVCLTIQKSSLDQ 664 Query: 665 LREGQIQSVVTYDLALDSGRPHSRAVFNETKNSTRRQTQVLGLTQTCETLKLQLPNCIED 724 L G IQS V +DLALD GR SRA+FNETKN T + + LGL CETLKL LP+C+ED Sbjct: 665 L--GDIQSSVRFDLALDPGRLTSRAIFNETKNPTLTRRKTLGLGIHCETLKLLLPDCVED 722 Query: 725 PVSPIVLRLNFSLVGTPLSAFGNLRPVLAEDAQRLFTALFPFEKNCGNDNICQDDLSITF 784 VSPI+L LNFSLV P+ + NLRPVLA +Q LFTA PFEKNCG D +C+ DL +T Sbjct: 723 VVSPIILHLNFSLVREPIPSPQNLRPVLAVGSQDLFTASLPFEKNCGQDGLCEGDLGVTL 782 Query: 785 SFMSLDCLVVGGPREFNVTVTVRNDGEDSYRTQVTFFFPLDLSYRKVSTLQNQRSQRSWR 844 SF L L VG E NV VTV N GEDSY T V+ ++P LS+R+VS Q Q Q + R Sbjct: 783 SFSGLQTLTVGSSLELNVIVTVWNAGEDSYGTVVSLYYPAGLSHRRVSGAQKQPHQSALR 842 Query: 845 LACESASSTEVSGALKSTSCSINHPIFPENSEVTFNITFDVDSKASLGNKLLLKANVTSE 904 LACE+ TE G L+S+ CS+NHPIF E S TF +TFDV KA+LG+++L++A+ +SE Sbjct: 843 LACETV-PTEDEG-LRSSRCSVNHPIFHEGSNGTFIVTFDVSYKATLGDRMLMRASASSE 900 Query: 905 NNMPRTNKTEFQLELPVKYAVYMVVTSHGVSTKYLNF-TASENTSRVMQHQYQVSNLGQR 963 NN ++K FQLELPVKYAVY +++ STKY NF T+ E + +H+Y+V+NL QR Sbjct: 901 NNKASSSKATFQLELPVKYAVYTMISRQEESTKYFNFATSDEKKMKEAEHRYRVNNLSQR 960 Query: 964 SLPISLVFLVPVRLNQTVIWDRPQVTFSENLSSTCHTKERLPSHSDFLAELRKAPVVNCS 1023 L IS+ F VPV LN +WD S++L C ++ + P HSDFL ++ ++P+++CS Sbjct: 961 DLAISINFWVPVLLNGVAVWDVVMEAPSQSL--PCVSERKPPQHSDFLTQISRSPMLDCS 1018 Query: 1024 IAVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYIKTSHNHLLIVSTAEILFNDSVFTLLP 1083 IA C + +CD+P F +QEE + TLKGNLSF W +T +L+VS AEI F+ SV++ LP Sbjct: 1019 IADCLQFRCDVPSFSVQEELDFTLKGNLSFGWVRETLQKKVLVVSVAEITFDTSVYSQLP 1078 Query: 1084 GQGAFVRSQTETKVEPFEVPNPLPLIVGSSVGGLLLLALITAALYKLGFFKRQYKDMMSE 1143 GQ AF+R+Q E +E EV N +P+I+GSSVG LLLLALITA LYKLGFFKR YK+M+ + Sbjct: 1079 GQEAFMRAQMEMVLEEDEVYNAIPIIMGSSVGALLLLALITATLYKLGFFKRHYKEMLED 1138 >gi|167466215 integrin alpha L isoform a precursor [Homo sapiens] Length = 1170 Score = 577 bits (1487), Expect = e-164 Identities = 393/1155 (34%), Positives = 603/1155 (52%), Gaps = 64/1155 (5%) Query: 17 FNLDTENAMTFQENARG--FGQSVVQLQGSRVVVGAPQEIVAANQRGSLYQCDYSTGSCE 74 +NLD A +F G FG V+Q+ G+ V+VGAP E N GSLYQC TG C Sbjct: 26 YNLDVRGARSFSPPRAGRHFGYRVLQV-GNGVIVGAPGE---GNSTGSLYQCQSGTGHCL 81 Query: 75 PIRLQVPVEAVNMSLGLSLAATTSPPQLLACGPTVHQTCSENTYVKGLCFLFGSNLRQQP 134 P+ L+ + LG++LA + +LAC P + +TC +NTY+ GLC+LF NL+ Sbjct: 82 PVTLRGS-NYTSKYLGMTLATDPTDGSILACDPGLSRTCDQNTYLSGLCYLFRQNLQGPM 140 Query: 135 QKFPEALRGCPQEDSDIAFLIDGSGSIIPHDFRRMKEFVSTVMEQLKKSKTLFSLMQYSE 194 + + C + + D+ FL DGS S+ P +F+++ +F+ VM++L + F+ +Q+S Sbjct: 141 LQGRPGFQECIKGNVDLVFLFDGSMSLQPDEFQKILDFMKDVMKKLSNTSYQFAAVQFST 200 Query: 195 EFRIHFTFKEFQNNPNPRSLVKPITQLLGRTHTATGIRKVVRELFNITNGARKNAFKILV 254 ++ F F ++ +P +L+K + +L T+T I V E+F GAR +A K+L+ Sbjct: 201 SYKTEFDFSDYVKRKDPDALLKHVKHMLLLTNTFGAINYVATEVFREELGARPDATKVLI 260 Query: 255 VITDGEKFGDPLGYEDVIPEADREGVIRYVIGVGDAFRSEKSRQELNTIASKPPRDHVFQ 314 +ITDGE G D + +IRY+IG+G F++++S++ L+ ASKP + V Sbjct: 261 IITDGE--ATDSGNIDAAKD-----IIRYIIGIGKHFQTKESQETLHKFASKPASEFVKI 313 Query: 315 VNNFEALKTIQNQLREKIFAIEGTQTGSSSSFEHEMSQEGFSAAITSNGPLLSTVGSYDW 374 ++ FE LK + +L++KI+ IEGT +SF E+S G SA ++ ++ VG+ DW Sbjct: 314 LDTFEKLKDLFTELQKKIYVIEGTSKQDLTSFNMELSSSGISADLSRGHAVVGAVGAKDW 373 Query: 375 AGGVF-LYTSKEKSTFINMTRVDSDMNDAYLGYAAA-IILRNRVQSLVLGAPRYQHIGLV 432 AGG L + TFI + ++ YLGY + R + L GAPRYQH+G V Sbjct: 374 AGGFLDLKADLQDDTFIGNEPLTPEVRAGYLGYTVTWLPSRQKTSLLASGAPRYQHMGRV 433 Query: 433 AMFR--QNTGMWESNANVKGTQIGAYFGASLCSVDVDSNGSTDLVLIGAPHYYEQTRGGQ 490 +F+ Q G W + GTQIG+YFG LC VDVD +G T+L+LIGAP +Y + RGG+ Sbjct: 434 LLFQEPQGGGHWSQVQTIHGTQIGSYFGGELCGVDVDQDGETELLLIGAPLFYGEQRGGR 493 Query: 491 VSVCPLPRGRARWQCDAVLYGEQGQPWGRFGAALTVLGDVNGDKLTDVAIGAPGEEDNRG 550 V + R + ++ + L G+ G P GRFG A+T L D+NGD L DVA+GAP EE +G Sbjct: 494 VFI--YQRRQLGFEEVSELQGDPGYPLGRFGEAITALTDINGDGLVDVAVGAPLEE--QG 549 Query: 551 AVYLFHGTSGSGISPSHSQRIAGSKLSPRLQYFGQSLSGGQDLTMDGLVDLTVGAQGHVL 610 AVY+F+G G G+SP SQRI G+++ +Q+FG+S+ G +DL DGL D+ VGA+ ++ Sbjct: 550 AVYIFNGRHG-GLSPQPSQRIEGTQVLSGIQWFGRSIHGVKDLEGDGLADVAVGAESQMI 608 Query: 611 LLRSQPVLRVKAIMEFNPREVARNVFECNDQVV-KGKEAGEVRVCLHVQKSTRDRLREGQ 669 +L S+PV+ + +M F+P E+ + EC+ K KE + +C + KS + +G+ Sbjct: 609 VLSSRPVVDMVTLMSFSPAEIPVHEVECSYSTSNKMKEGVNITICFQI-KSLIPQF-QGR 666 Query: 670 IQSVVTYDLALDSGRPHSRAVFNETKNSTRRQTQVLGLTQTCETLKLQLPNCIEDPVSPI 729 + + +TY L LD R R +F ++ RR V + +C P C++D +SPI Sbjct: 667 LVANLTYTLQLDGHRTRRRGLFPGGRHELRRNIAVT-TSMSCTDFSFHFPVCVQDLISPI 725 Query: 730 VLRLNFSL---VGTPLS--AFGNLRPVLAEDAQRLFTALFPFEKNCGNDNICQDDLSITF 784 + LNFSL GTP A G P + + T PFEKNCG D C+ +L ++F Sbjct: 726 NVSLNFSLWEEEGTPRDQRAQGKDIPPILRPSLHSETWEIPFEKNCGEDKKCEANLRVSF 785 Query: 785 SFMSLDCLVVGGPREFNVTVTVRNDGEDSYRTQVTFFFPLDLSYRKVSTLQNQRSQRSWR 844 S L + +V +++ N ED+Y Q+ FP LS+RKV L + Sbjct: 786 SPARSRALRLTAFASLSVELSLSNLEEDAYWVQLDLHFPPGLSFRKVEML---KPHSQIP 842 Query: 845 LACESASSTEVSGALKSTSCSINHPIFPENSEVTFNITFDVDSKASLGNKLLLKANVTSE 904 ++CE E ++ SC+++ PIF V + F+ +S G+ + L ANVT Sbjct: 843 VSCEELPE-ESRLLSRALSCNVSSPIFKAGHSVALQMMFNTLVNSSWGDSVELHANVTCN 901 Query: 905 N-NMPRTNKTEFQLELPVKYAVYMVVTSHGVSTKYLNFTASENTSRVMQHQYQV---SNL 960 N + +P+ Y + +++ ST Y++FT ++H YQV ++ Sbjct: 902 NEDSDLLEDNSATTIIPILYPINILIQDQEDSTLYVSFTPKGPKIHQVKHMYQVRIQPSI 961 Query: 961 GQRSLP-ISLVFLVPVRLNQTVIWDRPQVTFSENLSSTCHTKERLPSHSD--FLAELRKA 1017 ++P + V VP ++ I + V + ERLP ++ L + Sbjct: 962 HDHNIPTLEAVVGVPQPPSEGPITHQWSVQMEPPVPCHYEDLERLPDAAEPCLPGALFRC 1021 Query: 1018 PVVNCSIAVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYIKTSHNHLLIVSTAEILFNDS 1077 PVV ++E + G L I+ S + + S+ I FN S Sbjct: 1022 PVV------------------FRQEILVQVIGTLELVGEIEAS-SMFSLCSSLSISFNSS 1062 Query: 1078 VFTLLPGQGAFVRSQTETKVEPFEVPNPLPLIVGSSVGGLLLLALITAALYKLGFFKRQY 1137 L G A + +Q KV+ L L V S +GGLLLL LI LYK+GFFKR Sbjct: 1063 KHFHLYGSNASL-AQVVMKVDVVYEKQMLYLYVLSGIGGLLLLLLIFIVLYKVGFFKRNL 1121 Query: 1138 KDMMSEG-GPPGAEP 1151 K+ M G G P P Sbjct: 1122 KEKMEAGRGVPNGIP 1136 >gi|167466217 integrin alpha L isoform b precursor [Homo sapiens] Length = 1086 Score = 473 bits (1217), Expect = e-133 Identities = 340/1033 (32%), Positives = 520/1033 (50%), Gaps = 63/1033 (6%) Query: 143 GCPQEDSDIAFLID---GSGSIIPHDFR----RMKEFVSTVMEQLKKSKTLFSLMQYSEE 195 G P E + L G+G +P R K T+ LF+ +Q+S Sbjct: 59 GAPGEGNSTGSLYQCQSGTGHCLPVTLRGSNYTSKYLGMTLATDPTDGSILFAAVQFSTS 118 Query: 196 FRIHFTFKEFQNNPNPRSLVKPITQLLGRTHTATGIRKVVRELFNITNGARKNAFKILVV 255 ++ F F ++ +P +L+K + +L T+T I V E+F GAR +A K+L++ Sbjct: 119 YKTEFDFSDYVKRKDPDALLKHVKHMLLLTNTFGAINYVATEVFREELGARPDATKVLII 178 Query: 256 ITDGEKFGDPLGYEDVIPEADREGVIRYVIGVGDAFRSEKSRQELNTIASKPPRDHVFQV 315 ITDGE G D + +IRY+IG+G F++++S++ L+ ASKP + V + Sbjct: 179 ITDGEATDS--GNIDAAKD-----IIRYIIGIGKHFQTKESQETLHKFASKPASEFVKIL 231 Query: 316 NNFEALKTIQNQLREKIFAIEGTQTGSSSSFEHEMSQEGFSAAITSNGPLLSTVGSYDWA 375 + FE LK + +L++KI+ IEGT +SF E+S G SA ++ ++ VG+ DWA Sbjct: 232 DTFEKLKDLFTELQKKIYVIEGTSKQDLTSFNMELSSSGISADLSRGHAVVGAVGAKDWA 291 Query: 376 GGVF-LYTSKEKSTFINMTRVDSDMNDAYLGYAAA-IILRNRVQSLVLGAPRYQHIGLVA 433 GG L + TFI + ++ YLGY + R + L GAPRYQH+G V Sbjct: 292 GGFLDLKADLQDDTFIGNEPLTPEVRAGYLGYTVTWLPSRQKTSLLASGAPRYQHMGRVL 351 Query: 434 MFR--QNTGMWESNANVKGTQIGAYFGASLCSVDVDSNGSTDLVLIGAPHYYEQTRGGQV 491 +F+ Q G W + GTQIG+YFG LC VDVD +G T+L+LIGAP +Y + RGG+V Sbjct: 352 LFQEPQGGGHWSQVQTIHGTQIGSYFGGELCGVDVDQDGETELLLIGAPLFYGEQRGGRV 411 Query: 492 SVCPLPRGRARWQCDAVLYGEQGQPWGRFGAALTVLGDVNGDKLTDVAIGAPGEEDNRGA 551 + R + ++ + L G+ G P GRFG A+T L D+NGD L DVA+GAP EE +GA Sbjct: 412 FI--YQRRQLGFEEVSELQGDPGYPLGRFGEAITALTDINGDGLVDVAVGAPLEE--QGA 467 Query: 552 VYLFHGTSGSGISPSHSQRIAGSKLSPRLQYFGQSLSGGQDLTMDGLVDLTVGAQGHVLL 611 VY+F+G G G+SP SQRI G+++ +Q+FG+S+ G +DL DGL D+ VGA+ +++ Sbjct: 468 VYIFNGRHG-GLSPQPSQRIEGTQVLSGIQWFGRSIHGVKDLEGDGLADVAVGAESQMIV 526 Query: 612 LRSQPVLRVKAIMEFNPREVARNVFECNDQVV-KGKEAGEVRVCLHVQKSTRDRLREGQI 670 L S+PV+ + +M F+P E+ + EC+ K KE + +C + KS + +G++ Sbjct: 527 LSSRPVVDMVTLMSFSPAEIPVHEVECSYSTSNKMKEGVNITICFQI-KSLIPQF-QGRL 584 Query: 671 QSVVTYDLALDSGRPHSRAVFNETKNSTRRQTQVLGLTQTCETLKLQLPNCIEDPVSPIV 730 + +TY L LD R R +F ++ RR V + +C P C++D +SPI Sbjct: 585 VANLTYTLQLDGHRTRRRGLFPGGRHELRRNIAVT-TSMSCTDFSFHFPVCVQDLISPIN 643 Query: 731 LRLNFSL---VGTPL-SAFGNLRPVLAEDAQRLFTALFPFEKNCGNDNICQDDLSITFSF 786 + LNFSL GTP G P + + T PFEKNCG D C+ +L ++FS Sbjct: 644 VSLNFSLWEEEGTPRDQRAGKDIPPILRPSLHSETWEIPFEKNCGEDKKCEANLRVSFSP 703 Query: 787 MSLDCLVVGGPREFNVTVTVRNDGEDSYRTQVTFFFPLDLSYRKVSTLQNQRSQRSWRLA 846 L + +V +++ N ED+Y Q+ FP LS+RKV L + ++ Sbjct: 704 ARSRALRLTAFASLSVELSLSNLEEDAYWVQLDLHFPPGLSFRKVEML---KPHSQIPVS 760 Query: 847 CESASSTEVSGALKSTSCSINHPIFPENSEVTFNITFDVDSKASLGNKLLLKANVTSEN- 905 CE E ++ SC+++ PIF V + F+ +S G+ + L ANVT N Sbjct: 761 CEELPE-ESRLLSRALSCNVSSPIFKAGHSVALQMMFNTLVNSSWGDSVELHANVTCNNE 819 Query: 906 NMPRTNKTEFQLELPVKYAVYMVVTSHGVSTKYLNFTASENTSRVMQHQYQV---SNLGQ 962 + +P+ Y + +++ ST Y++FT ++H YQV ++ Sbjct: 820 DSDLLEDNSATTIIPILYPINILIQDQEDSTLYVSFTPKGPKIHQVKHMYQVRIQPSIHD 879 Query: 963 RSLP-ISLVFLVPVRLNQTVIWDRPQVTFSENLSSTCHTKERLPSHSD--FLAELRKAPV 1019 ++P + V VP ++ I + V + ERLP ++ L + PV Sbjct: 880 HNIPTLEAVVGVPQPPSEGPITHQWSVQMEPPVPCHYEDLERLPDAAEPCLPGALFRCPV 939 Query: 1020 VNCSIAVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYIKTSHNHLLIVSTAEILFNDSVF 1079 V ++E + G L I+ S + + S+ I FN S Sbjct: 940 V------------------FRQEILVQVIGTLELVGEIEAS-SMFSLCSSLSISFNSSKH 980 Query: 1080 TLLPGQGAFVRSQTETKVEPFEVPNPLPLIVGSSVGGLLLLALITAALYKLGFFKRQYKD 1139 L G A + +Q KV+ L L V S +GGLLLL LI LYK+GFFKR K+ Sbjct: 981 FHLYGSNASL-AQVVMKVDVVYEKQMLYLYVLSGIGGLLLLLLIFIVLYKVGFFKRNLKE 1039 Query: 1140 MMSEG-GPPGAEP 1151 M G G P P Sbjct: 1040 KMEAGRGVPNGIP 1052 Score = 58.2 bits (139), Expect = 5e-08 Identities = 132/529 (24%), Positives = 213/529 (40%), Gaps = 100/529 (18%) Query: 17 FNLDTENAMTFQENARG--FGQSVVQLQGSRVVVGAPQEIVAANQRGSLYQCDYSTGSCE 74 +NLD A +F G FG V+Q+ G+ V+VGAP E N GSLYQC TG C Sbjct: 26 YNLDVRGARSFSPPRAGRHFGYRVLQV-GNGVIVGAPGE---GNSTGSLYQCQSGTGHCL 81 Query: 75 PIRLQVPVEAVNMSLGLSLAATTSPPQLLACG---PTVHQTCSE-NTYVKG--------- 121 P+ L+ + LG++LA + +L T ++T + + YVK Sbjct: 82 PVTLR-GSNYTSKYLGMTLATDPTDGSILFAAVQFSTSYKTEFDFSDYVKRKDPDALLKH 140 Query: 122 ------LCFLFGSNLRQQPQKFPEALRGCPQEDSDIAFLIDG----SGSI---------- 161 L FG+ + F E L P + + DG SG+I Sbjct: 141 VKHMLLLTNTFGAINYVATEVFREELGARPDATKVLIIITDGEATDSGNIDAAKDIIRYI 200 Query: 162 --------------IPHDF--RRMKEFVSTVMEQLKKSKTLFSLMQYSEEFRIHFTFKEF 205 H F + EFV +++ +K K LF+ +Q + + I T K+ Sbjct: 201 IGIGKHFQTKESQETLHKFASKPASEFVK-ILDTFEKLKDLFTELQ-KKIYVIEGTSKQD 258 Query: 206 QNNPNPRSLVKPITQLLGRTHTATGIRKVVRELFNITNGARKNAFKILVVITDGEKFGDP 265 + N I+ L R H G GA+ A L + D + Sbjct: 259 LTSFNMELSSSGISADLSRGHAVVG-----------AVGAKDWAGGFLDLKADLQD-DTF 306 Query: 266 LGYEDVIPEADREGVIRYVIGVGDAFRSEKSRQELNTIASKPPR-DHVFQVNNFEALKTI 324 +G E + PE R G + Y + SRQ+ + +AS PR H+ +V F+ + Sbjct: 307 IGNEPLTPEV-RAGYLGYTV------TWLPSRQKTSLLASGAPRYQHMGRVLLFQEPQGG 359 Query: 325 QNQLREKIFAIEGTQTGSSSSFE---HEMSQEGFSAAITSNGPLLSTVGSYDWAGGVFLY 381 + ++ I GTQ GS E ++ Q+G + + PL G VF+Y Sbjct: 360 GHW--SQVQTIHGTQIGSYFGGELCGVDVDQDGETELLLIGAPLFY---GEQRGGRVFIY 414 Query: 382 TSKEKSTFINMTRVDSDMNDAYLGYAAAI-----ILRNRVQSLVLGAPRYQHIGLVAMFR 436 ++ F ++ + D + AI I + + + +GAP + G V +F Sbjct: 415 QRRQLG-FEEVSELQGDPGYPLGRFGEAITALTDINGDGLVDVAVGAP-LEEQGAVYIFN 472 Query: 437 QNTG--MWESNANVKGTQIGA---YFGASLCSV-DVDSNGSTDLVLIGA 479 G + + ++GTQ+ + +FG S+ V D++ +G D V +GA Sbjct: 473 GRHGGLSPQPSQRIEGTQVLSGIQWFGRSIHGVKDLEGDGLAD-VAVGA 520 >gi|148728188 integrin, alpha E precursor [Homo sapiens] Length = 1179 Score = 417 bits (1073), Expect = e-116 Identities = 305/1013 (30%), Positives = 504/1013 (49%), Gaps = 69/1013 (6%) Query: 149 SDIAFLIDGSGSIIPHDFRRMKEFVSTVMEQL--KKSKTLFSLMQYSEEFRIHFTFKEFQ 206 ++IA ++DGSGSI P DF+R K+F+S +M K + F+L+QY + F ++ Q Sbjct: 201 TEIAIILDGSGSIDPPDFQRAKDFISNMMRNFYEKCFECNFALVQYGGVIQTEFDLRDSQ 260 Query: 207 NNPNPRSLVKPITQLLGRTHTATGIRKVVRELFNITNGARKNAFKILVVITDGEKFGDPL 266 + + V+ ITQ+ T TA+ ++ V+ +F ++G+R+ A K++VV+TDG F DPL Sbjct: 261 DVMASLARVQNITQVGSVTKTASAMQHVLDSIFTSSHGSRRKASKVMVVLTDGGIFEDPL 320 Query: 267 GYEDVIPEADREGVIRYVIGVGDAFRSEKSRQELNTIASKPPRDHVFQVNNFEALKTIQN 326 VI +GV R+ IGVG+ F+S ++ +ELN IAS P H F+V N+ AL + + Sbjct: 321 NLTTVINSPKMQGVERFAIGVGEEFKSARTARELNLIASDPDETHAFKVTNYMALDGLLS 380 Query: 327 QLREKIFAIEGTQTGSSSSFEHEMSQEGFSAAITSNGP-LLSTVGSYDWAGGVFLY-TSK 384 +LR I ++EGT + ++++Q GFSA I LL VG++DW+GG LY T Sbjct: 381 KLRYNIISMEGT---VGDALHYQLAQIGFSAQILDERQVLLGAVGAFDWSGGALLYDTRS 437 Query: 385 EKSTFINMTRVDSDMNDA----YLGYAAAIILRNRVQSLVLGAPRYQHIGLVAMFRQNTG 440 + F+N T + +A YLGYA A++ + S + GAPRY+H G V ++ Sbjct: 438 RRGRFLNQTAAAAADAEAAQYSYLGYAVAVLHKTCSLSYIAGAPRYKHHGAVFELQKEGR 497 Query: 441 MWESNANVKGTQIGAYFGASLCSVDVDSNGSTDLVLIGAPHYYEQTRGGQVSVCPLPRGR 500 ++G Q+G+YFG+ LC VD+D +GSTD +L+ AP Y+ G+V V L Sbjct: 498 EASFLPVLEGEQMGSYFGSELCPVDIDMDGSTDFLLVAAPFYHVHGEEGRVYVYRLSEQD 557 Query: 501 ARWQCDAVLYGEQGQPWGRFGAALTVLGDVNGDKLTDVAIGAP----GEEDNR--GAVYL 554 + +L G G RFG A+ +GD++ DKLTDVAIGAP G +D G+VY+ Sbjct: 558 GSFSLARILSGHPGFTNARFGFAMAAMGDLSQDKLTDVAIGAPLEGFGADDGASFGSVYI 617 Query: 555 FHGTSGSGISPSHSQRIAGSKLSPRLQYFGQSLSGGQDLTMDGLVDLTVGAQGHVLLLRS 614 ++G G+S S SQRI S ++P LQYFG S++GG D++ DGL D+TVG G ++ RS Sbjct: 618 YNG-HWDGLSASPSQRIRASTVAPGLQYFGMSMAGGFDISGDGLADITVGTLGQAVVFRS 676 Query: 615 QPVLRVKAIMEFNPREVARNVFECNDQVVKGKEAGEVRVCLHVQKSTRDRLREGQIQSVV 674 +PV+R+K M F P + + VR+C + S G ++++ Sbjct: 677 RPVVRLKVSMAFTPSALP----------IGFNGVVNVRLCFEI-SSVTTASESGLREALL 725 Query: 675 TYDLALDSGRPHSRAVFNETKNSTRRQTQVLGLTQTCETLKLQLPN----CIEDPVSPIV 730 + L +D G+ R ++ ++ + +Q CE L L +P C ED S Sbjct: 726 NFTLDVDVGKQRRRLQCSDVRSCLGCLREWSSGSQLCEDL-LLMPTEGELCEEDCFSNAS 784 Query: 731 LRLNFSLVGTPLSAFGNLRPVLAEDAQRLFTALFPFEKNCGNDNICQDDLSITFSFMSLD 790 +++++ L TP + +P+L + P+EK C N C +L + + +S Sbjct: 785 VKVSYQL-QTPEGQTDHPQPILDRYTEPFAIFQLPYEKACKNKLFCVAELQLA-TTVSQQ 842 Query: 791 CLVVGGPREFNVTVTVRNDGEDSYRTQVTFFFPLDLSYRKVSTLQNQRSQRSWRLACESA 850 LVVG +E + + + N GEDSY T + +P +L L+ + S + C+ Sbjct: 843 ELVVGLTKELTLNINLTNSGEDSYMTSMALNYPRNLQ------LKRMQKPPSPNIQCDDP 896 Query: 851 SSTEVSGALKSTSCSINHPIFPENSEVTFNITFDVDSKASLGNKLLLKANVTSENNMPRT 910 ++ +C I HP+ + S ++ + ++ A + VT+ N R Sbjct: 897 QPV---ASVLIMNCRIGHPVL-KRSSAHVSVVWQLEENAFPNRTADITVTVTNSNE--RR 950 Query: 911 NKTEFQLELPVKYAVYMVVTSHGVSTKYLNFTASENTSRVMQHQYQVSNLGQRSLPISLV 970 + L ++ V++ S Y+N + S + + V L Sbjct: 951 SLANETHTLQFRHGFVAVLSK--PSIMYVN--TGQGLSHHKEFLFHVHGENLFGAEYQLQ 1006 Query: 971 FLVPVRLNQTVIWDRPQVTFSENLSSTCHTKERLPSHSDFLAELRKAPVVNCSIAVCQRI 1030 VP +L + ++T ++ + ++ER ++S + + + V+C IA Sbjct: 1007 ICVPTKLRGLQVVAVKKLTRTQASTVCTWSQERACAYSS-VQHVEEWHSVSCVIA----- 1060 Query: 1031 QCDIPFFGIQEEFNATLKGNLSFDWYIKTSHNHLLIVSTAEILFNDSVFTLLPGQGAFVR 1090 ++ N T+ +S+D + + + EI FN S++ L + R Sbjct: 1061 ---------SDKENVTVAAEISWDHSEELLKDVTELQILGEISFNKSLYEGLNAENH--R 1109 Query: 1091 SQTETKVEPFEVPNPLPLIVGSSVGGLLLLALITAALYKLGFFKRQYKDMMSE 1143 ++ E + LP+I+ SVGGLL+L +I L+K GFFKR+Y+ + E Sbjct: 1110 TKITVVFLKDEKYHSLPIIIKGSVGGLLVLIVILVILFKCGFFKRKYQQLNLE 1162 >gi|239751058 PREDICTED: hypothetical protein XP_002347690 [Homo sapiens] Length = 462 Score = 406 bits (1043), Expect = e-113 Identities = 231/444 (52%), Positives = 279/444 (62%), Gaps = 53/444 (11%) Query: 751 VLAEDAQRLFTALFPFEKNCGNDNICQDDLSITFSFMSLDCLVVGGPREFNVTVTVRNDG 810 +LA DAQR FTA PFEKNCG D+ICQD+L I+FSF L L+VG E N V V NDG Sbjct: 1 MLAADAQRYFTASLPFEKNCGADHICQDNLGISFSFPGLKSLLVGSNLELNAEVMVWNDG 60 Query: 811 EDSYRTQVTFFFPLDLSYRKVSTLQNQRSQRSWRLACESASSTEVSGALKSTSCSINHPI 870 EDSY T +TF P LSYR V+ Q Q RS L C+SA S STSC INH I Sbjct: 61 EDSYGTTITFSHPAGLSYRYVAEGQKQGQLRSLHLTCDSAPVG--SQGTWSTSCRINHLI 118 Query: 871 FPENSEVTFNITFDVDSKASLGNKLLLKANVTSENNMPRTNKTEFQLELPVKYAVYMVVT 930 F +++TF TFDV KA LG++LLL ANV+SENN PRT+KT FQLELPVKYAVY VV+ Sbjct: 119 FRGGAQITFLATFDVSPKAVLGDRLLLTANVSSENNTPRTSKTTFQLELPVKYAVYTVVS 178 Query: 931 SHGVSTKYLNFTAS-ENTSRVMQHQYQ-----------VSNLGQRSLPISLVFLVPVRLN 978 SH TKYLNF+ S E S V H+YQ V+NLGQR LP+S+ F VPV LN Sbjct: 179 SHEQFTKYLNFSESEEKESHVAMHRYQAGGGDAGDWAGVNNLGQRDLPVSINFWVPVELN 238 Query: 979 QTVIW-----DRPQV----------------------------------TFSENLSSTCH 999 Q +W PQV F +N S C Sbjct: 239 QEAVWMDVEVSHPQVPKDCMWLLHECPFYLDSLCPMWVPDVPAETLVLCIFPQNPSLRCS 298 Query: 1000 TKERLPSHSDFLAELRKAPVVNCSIAVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYIKT 1059 +++ P SDFLA ++K PV++CSIA C R +CD+P F +QEE + TLKGNLSF W + Sbjct: 299 SEKIAPPASDFLAHIQKNPVLDCSIAGCLRFRCDVPSFSVQEELDFTLKGNLSFGWVRQI 358 Query: 1060 SHNHLLIVSTAEILFNDSVFTLLPGQGAFVRSQTETKVEPFEVPNPLPLIVGSSVGGLLL 1119 + +VS AEI F+ SV++ LPGQ AF+R+QT T +E ++V NP PLIVGSS+GGLLL Sbjct: 359 LQKKVSVVSVAEITFDTSVYSQLPGQEAFMRAQTTTVLEKYKVHNPTPLIVGSSIGGLLL 418 Query: 1120 LALITAALYKLGFFKRQYKDMMSE 1143 LALITA LYK+GFFKRQYK+MM E Sbjct: 419 LALITAVLYKVGFFKRQYKEMMEE 442 >gi|31657142 integrin, alpha 1 precursor [Homo sapiens] Length = 1179 Score = 397 bits (1021), Expect = e-110 Identities = 346/1214 (28%), Positives = 554/1214 (45%), Gaps = 128/1214 (10%) Query: 6 LLLTALTLCHGFNLDTENAMTFQENARG-FGQSVVQLQ---GSRVVVGAPQEIVAANQRG 61 LL L C FN+D +N+MTF FG +V Q + G V++G+P N+ G Sbjct: 18 LLTVVLRCCVSFNVDVKNSMTFSGPVEDMFGYTVQQYENEEGKWVLIGSPLVGQPKNRTG 77 Query: 62 SLYQCDYSTGSCEP-IRLQVPVEAV---------NMSLGLSLAATTSPPQLLACGPTVHQ 111 +Y+C G P ++L +PV NM+ G +L T LACGP Sbjct: 78 DVYKCPVGRGESLPCVKLDLPVNTSIPNVTEVKENMTFGSTLV-TNPNGGFLACGPLYAY 136 Query: 112 TCSENTYVKGLCFLFGSNLRQQPQKFPEALRGCPQEDSDIAFLIDGSGSIIPHDFRRMKE 171 C Y G+C + P ++ C + DI ++DGS SI P D + Sbjct: 137 RCGHLHYTTGICSDVSPTFQVVNSIAP--VQECSTQ-LDIVIVLDGSNSIYPWD--SVTA 191 Query: 172 FVSTVMEQLK--KSKTLFSLMQYSEEFRIHFTFKEFQNNPNPRSLVKPITQLLGR-THTA 228 F++ ++E++ +T ++QY E F ++ + K I Q GR T TA Sbjct: 192 FLNDLLERMDIGPKQTQVGIVQYGENVTHEFNLNKYSSTEEVLVAAKKIVQRGGRQTMTA 251 Query: 229 TGIRKVVRELFNITNGARKNAFKILVVITDGEKFGDPLGYEDVIPEADREGVIRYVIGVG 288 GI +E F GAR+ K++V++TDGE D + VI + + E + R+ I + Sbjct: 252 LGIDTARKEAFTEARGARRGVKKVMVIVTDGESH-DNHRLKKVIQDCEDENIQRFSIAIL 310 Query: 289 DAFR-----SEKSRQELNTIASKPPRDHVFQVNNFEALKTIQNQLREKIFAIEGTQTGSS 343 ++ +EK +E+ +IAS+P H F V++ AL TI L E+IFA+E T S+ Sbjct: 311 GSYNRGNLSTEKFVEEIKSIASEPTEKHFFNVSDELALVTIVKTLGERIFALEATADQSA 370 Query: 344 SSFEHEMSQEGFSAAITSNGPLLSTVGSYDWAGGVFLYTSKE-----KSTFINMTRVDSD 398 +SFE EMSQ GFSA + + +L VG+YDW G V + + + +TF + ++ Sbjct: 371 ASFEMEMSQTGFSAHYSQDWVMLGAVGAYDWNGTVVMQKASQIIIPRNTTFNVESTKKNE 430 Query: 399 MNDAYLGYAAAIILRNRVQSL-VLGAPRYQHIGLVAMFRQNTGMWESNANVKGTQIGAYF 457 +YLGY + L + G PRY H G V ++R G + + G QIG+YF Sbjct: 431 PLASYLGYTVNSATASSGDVLYIAGQPRYNHTGQVIIYRMEDGNIKILQTLSGEQIGSYF 490 Query: 458 GASLCSVDVDSNGSTDLVLIGAPHYY--EQTRGGQVSVCPLPRGRARWQ----------C 505 G+ L + D+D + +TD++L+GAP Y E+ G+V V L + R +Q C Sbjct: 491 GSILTTTDIDKDSNTDILLVGAPMYMGTEKEEQGKVYVYALNQTRFEYQMSLEPIKQTCC 550 Query: 506 DAVLYG-----EQGQPWG-RFGAALTVLGDVNGDKLTDVAIGAPGEEDNRGAVYLFHGTS 559 + + + +P G RFG A+ + D+N D D+ IGAP E+D+ GAVY++HG S Sbjct: 551 SSRQHNSCTTENKNEPCGARFGTAIAAVKDLNLDGFNDIVIGAPLEDDHGGAVYIYHG-S 609 Query: 560 GSGISPSHSQRIAGSKLSPRLQYFGQSLSGGQDLTMDGLVDLTVGAQGHVLLLRSQPVLR 619 G I ++QRI L++FGQS+ G DL DGL D+T+G G L S+ V Sbjct: 610 GKTIRKEYAQRIPSGGDGKTLKFFGQSIHGEMDLNGDGLTDVTIGGLGGAALFWSRDVAV 669 Query: 620 VKAIMEFNPREVARNVFECNDQVVKGKEAG--EVRVCLHVQ-KSTRDRLREGQIQSVVTY 676 VK M F P +V C+ ++GKE VC V+ KS D + E +Q Y Sbjct: 670 VKVTMNFEPNKVNIQKKNCH---MEGKETVCINATVCFDVKLKSKEDTIYEADLQ----Y 722 Query: 677 DLALDSGRPHSRAVFNET-KNSTRRQTQVLGLTQTCETLKLQLPNCIEDPVSPIVLRLNF 735 + LDS R SR+ F+ T + +R V T + + + +D V + L+F Sbjct: 723 RVTLDSLRQISRSFFSGTQERKVQRNITVRKSECTKHSFYMLDKHDFQDSVR---ITLDF 779 Query: 736 SLVGTPLSAFGNLRPVLAEDAQRLFTALFPFEKNCGNDNICQDDLSITFSFMSLDCLVVG 795 +L PVL + PF K+CGN C DLS+ + D L+V Sbjct: 780 NLTDPENG------PVLDDSLPNSVHEYIPFAKDCGNKEKCISDLSLHVATTEKDLLIVR 833 Query: 796 GPRE-FNVTVTVRNDGEDSYRTQVTFFFPLDLSYRKVSTLQNQRSQRSWRLACESASSTE 854 + FNV++TV+N + +Y T+ + +L + + +Q +CES Sbjct: 834 SQNDKFNVSLTVKNTKDSAYNTRTIVHYSPNLVFSGIEAIQKD--------SCESN---- 881 Query: 855 VSGALKSTSCSINHPIFPENSEVTFNITFDVDSKASLGN-KLLLKANVTSENNMPRTNKT 913 + +C + +P VTF I F ++ + N + L A SE + Sbjct: 882 -----HNITCKVGYPFLRRGEMVTFKILFQFNTSYLMENVTIYLSATSDSEEPPETLSDN 936 Query: 914 EFQLELPVKYAVYMVVTSHGVSTKYLNFTASENTSRVMQHQYQVSN-------------L 960 + +PVKY V + S S +++ A+E V+ + N Sbjct: 937 VVNISIPVKYEVGLQFYS-SASEYHISIAANETVPEVINSTEDIGNEINIFYLIRKSGSF 995 Query: 961 GQRSLPISLVFLVPVRLNQTVIWDRPQVTFSENLSSTCHTKE---------RLPSHSDFL 1011 L +S+ F V++ ++ SEN + H E ++ + +D Sbjct: 996 PMPELKLSISFPNMTSNGYPVLYP-TGLSSSENANCRPHIFEDPFSINSGKKMTTSTD-- 1052 Query: 1012 AELRKAPVVNCSIAVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYIKTSHNHLLIVSTAE 1071 L++ +++C+ I C++ I + N +L L +IK+ + L + E Sbjct: 1053 -HLKRGTILDCNTCKFATITCNLTSSDI-SQVNVSL--ILWKPTFIKSYFSSLNLTIRGE 1108 Query: 1072 ILFNDSVFTLLPGQGAFVRSQTETKVEPFEVPNPLPL--IVGSSVGGLLLLALITAALYK 1129 + ++ L + + + ++ +P +PL I+ S+ GLLLL L+ AL+K Sbjct: 1109 LRSENASLVL---SSSNQKRELAIQISKDGLPGRVPLWVILLSAFAGLLLLMLLILALWK 1165 Query: 1130 LGFFKRQYKDMMSE 1143 +GFFKR K M + Sbjct: 1166 IGFFKRPLKKKMEK 1179 >gi|52485853 integrin, alpha 11 precursor [Homo sapiens] Length = 1188 Score = 380 bits (977), Expect = e-105 Identities = 340/1196 (28%), Positives = 540/1196 (45%), Gaps = 126/1196 (10%) Query: 17 FNLDTENAMTFQENARGFGQSVVQ---LQGSR-VVVGAPQEIVAANQRGSLYQCDYSTGS 72 FN+DT + F VQ + G++ +VVGAP E + G +Y+C G+ Sbjct: 23 FNMDTRKPRVIPGSRTAFFGYTVQQHDISGNKWLVVGAPLETNGYQKTGDVYKCPVIHGN 82 Query: 73 CEPIRL------QVPVEAVNMSLGLSLAATTSPPQLLACGPTVHQTCSENTYVKGLCFLF 126 C + L V NM LGLSLA LAC P C + Y G+C Sbjct: 83 CTKLNLGRVTLSNVSERKDNMRLGLSLATNPKDNSFLACSPLWSHECGSSYYTTGMCSRV 142 Query: 127 GSNLRQQPQKFPEALRGCPQEDSDIAFLIDGSGSIIPHDFRRMKEFVSTVMEQ--LKKSK 184 SN R P AL+ C Q DI ++DGS SI P + ++ F+ ++++ + + Sbjct: 143 NSNFRFSKTVAP-ALQRC-QTYMDIVIVLDGSNSIYP--WVEVQHFLINILKKFYIGPGQ 198 Query: 185 TLFSLMQYSEEFRIHFTFKEFQNNPNPRSLVKPITQLLG-RTHTATGIRKVVRELFNITN 243 ++QY E+ F ++++ + I Q G T TA GI E F Sbjct: 199 IQVGVVQYGEDVVHEFHLNDYRSVKDVVEAASHIEQRGGTETRTAFGIEFARSEAFQ--K 256 Query: 244 GARKNAFKILVVITDGEKFGDPLGYEDVIPEADREGVIRYVIGVGDAFRS-----EKSRQ 298 G RK A K+++VITDGE P E VI +++R+ V RY + V + E Sbjct: 257 GGRKGAKKVMIVITDGESHDSP-DLEKVIQQSERDNVTRYAVAVLGYYNRRGINPETFLN 315 Query: 299 ELNTIASKPPRDHVFQVNNFEALKTIQNQLREKIFAIEGTQTGSSSSFEHEMSQEGFSAA 358 E+ IAS P H F V + ALK I + L ++IF++EGT + +SF EMSQ GFS+ Sbjct: 316 EIKYIASDPDDKHFFNVTDEAALKDIVDALGDRIFSLEGTNK-NETSFGLEMSQTGFSSH 374 Query: 359 ITSNGPLLSTVGSYDWAGGVFLYTSKEK-----STFINMTRVDSDMNDAYLGYAAAIILR 413 + +G LL VG+YDW G V TS K +++ + + AYLGY ++ Sbjct: 375 VVEDGVLLGAVGAYDWNGAVLKETSAGKVIPLRESYLKEFPEELKNHGAYLGYTVTSVVS 434 Query: 414 NRVQSL-VLGAPRYQHIGLVAMFRQ-NTGMWESNANVKGTQIGAYFGASLCSVDVDSNGS 471 +R + V GAPR+ H G V +F N + ++G QIG+YFG+ + SVD+D +G Sbjct: 435 SRQGRVYVAGAPRFNHTGKVILFTMHNNRSLTIHQAMRGQQIGSYFGSEITSVDIDGDGV 494 Query: 472 TDLVLIGAPHYYEQTRG-GQVSVCPLPRGRARWQCDAVLYGEQGQPWGRFGAALTVLGDV 530 TD++L+GAP Y+ + R G+V V L + + + L RFG+++ + D+ Sbjct: 495 TDVLLVGAPMYFNEGRERGKVYVYELRQNLFVY--NGTLKDSHSYQNARFGSSIASVRDL 552 Query: 531 NGDKLTDVAIGAPGEEDNRGAVYLFHGTSGSGISPSHSQRIAGSKLSPRLQYFGQSLSGG 590 N D DV +GAP E+++ GA+Y+FHG GS I + QRI S+L+ LQYFG S+ G Sbjct: 553 NQDSYNDVVVGAPLEDNHAGAIYIFHGFRGS-ILKTPKQRITASELATGLQYFGCSIHGQ 611 Query: 591 QDLTMDGLVDLTVGAQGHVLLLRSQPVLRVKAIMEFNPREVARNVF--ECNDQVVKGKEA 648 DL DGL+DL VGA G+ ++L S+PV+++ A + F P ++ N+F +C K + Sbjct: 612 LDLNEDGLIDLAVGALGNAVILWSRPVVQINASLHFEPSKI--NIFHRDC-------KRS 662 Query: 649 GEVRVCLHVQKSTRDRLREGQIQSV---VTYDLALDSGRPHSRAVFNETKNS-TRRQTQV 704 G CL Q+ + Y+ +D R RA +E + T R + Sbjct: 663 GRDATCLAAFLCFTPIFLAPHFQTTTVGIRYNATMDERRYTPRAHLDEGGDRFTNRAVLL 722 Query: 705 LGLTQTCETLKLQLPNCIEDPVSPIVLRLNFSLVGTPLSAFGNLRPVLAEDAQRLFTALF 764 + CE + + + D V P+ + +SL + P+L + Sbjct: 723 SSGQELCERINFHVLD-TADYVKPVTFSVEYSLEDP------DHGPMLDDGWPTTLRVSV 775 Query: 765 PFEKNCGNDNICQDDL---------------------------SITFSFMSLDCLVVGGP 797 PF C D C DL + T SF + ++ Sbjct: 776 PFWNGCNEDEHCVPDLVLDARSDLPTAMEYCQRVLRKPAQDCSAYTLSFDTTVFIIESTR 835 Query: 798 REFNVTVTVRNDGEDSYRTQVTFFFPLDLSYRKVSTLQNQRSQRSWRLACESASSTEVSG 857 + V T+ N GE++Y T + +L + S +Q + S S E Sbjct: 836 QRVAVEATLENRGENAYSTVLNISQSANLQF--ASLIQKEDSDGSIECVNEER------- 886 Query: 858 ALKSTSCSINHPIFPENSEVTFNITFDVDSKASLGNKLLLKANVTSENNMPRTNKTE--F 915 L+ C++++P F ++V F + F+ SK+ + L ++ S++N + K + Sbjct: 887 RLQKQVCNVSYPFFRAKAKVAFRLDFEF-SKSIFLHHLEIELAAGSDSNERDSTKEDNVA 945 Query: 916 QLELPVKYAVYMVVTSHGVSTKYLNFTASENTSRVMQHQ--------YQVSNLGQ---RS 964 L +KY ++ T S+ ++ N+S +++ NLG Sbjct: 946 PLRFHLKYEADVLFTR---SSSLSHYEVKPNSSLERYDGIGPPFSCIFRIQNLGLFPIHG 1002 Query: 965 LPISLVFLVPVRLNQTVIWDRPQVTFSENLSSTCHTKERLPSHSDFLAELRKAPVVNCSI 1024 + + + + R ++ R +T N S + +LR+AP +N S Sbjct: 1003 MMMKITIPIATRSGNRLLKLRDFLTDEANTSCNIWGNSTEYRPTPVEEDLRRAPQLNHSN 1062 Query: 1025 AVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYIKTSHNHLLIVSTAEILFNDSVFTLLPG 1084 + I C+I +E N L GNL W L + +I+ N ++ Sbjct: 1063 SDVVSINCNIRLVP-NQEINFHLLGNL---WLRSLK---ALKYKSMKIMVNAALQRQFHS 1115 Query: 1085 QGAFVRSQTETKVEPFEVPN------PLPLIVGSSVGGLLLLALITAALYKLGFFK 1134 F R + ++ FE+ P+ +IVGS++GGLLLLAL+ AL+KLGFF+ Sbjct: 1116 PFIF-REEDPSRQIVFEISKQEDWQVPIWIIVGSTLGGLLLLALLVLALWKLGFFR 1170 >gi|38569398 integrin, alpha 10 precursor [Homo sapiens] Length = 1167 Score = 380 bits (977), Expect = e-105 Identities = 345/1173 (29%), Positives = 551/1173 (46%), Gaps = 93/1173 (7%) Query: 13 LCHGFNLDTENAMTFQENARG-FGQSVVQLQGSR---VVVGAPQEIVAANQRGSLYQC-- 66 LC FNLD + F FG SV+Q G ++VGAP + + ++RG +Y+C Sbjct: 19 LCSPFNLDEHHPRLFPGPPEAEFGYSVLQHVGGGQRWMLVGAPWDGPSGDRRGDVYRCPV 78 Query: 67 --------------DYSTGSCEPIRLQVPVEAVNMSLGLSLAATTSPPQLLACGPTVHQT 112 DY G+ AVNM LG+SL T +AC P + Sbjct: 79 GGAHNAPCAKGHLGDYQLGNSSH-------PAVNMHLGMSLLETDGDGGFMACAPLWSRA 131 Query: 113 CSENTYVKGLCFLFGSNLRQQPQKFPEALRGCPQEDSDIAFLIDGSGSIIPHDFRRMKEF 172 C + + G+C ++ + Q P A R CP D+ ++DGS SI P + ++ F Sbjct: 132 CGSSVFSSGICARVDASFQPQGSLAPTAQR-CPTY-MDVVIVLDGSNSIYP--WSEVQTF 187 Query: 173 VSTVMEQL--KKSKTLFSLMQYSEEFRIHFTFKEFQNNPNPRSLVKPITQLLGR-THTAT 229 + ++ +L + L+QY E ++ +F+ K +++ GR T TA Sbjct: 188 LRRLVGKLFIDPEQIQVGLVQYGESPVHEWSLGDFRTKEEVVRAAKNLSRREGRETKTAQ 247 Query: 230 GIRKVVRELFNITNGARKNAFKILVVITDGEKF-GDPLGYEDVIPEADREGVIRYVIGV- 287 I E F+ ++G R A ++LVV+TDGE G+ L EA R V RY I V Sbjct: 248 AIMVACTEGFSQSHGGRPEAARLLVVVTDGESHDGEELPAALKACEAGR--VTRYGIAVL 305 Query: 288 GDAFRSEKSR----QELNTIASKPPRDHVFQVNNFEALKTIQNQLREKIFAIEGTQTGSS 343 G R ++ +E+ TIAS P F V + AL I + L ++IF +EG+ + Sbjct: 306 GHYLRRQRDPSSFLREIRTIASDPDERFFFNVTDEAALTDIVDALGDRIFGLEGSHAENE 365 Query: 344 SSFEHEMSQEGFSAAITSNGPLLSTVGSYDWAGGVFLYTSKEKSTFINMTRVDS-----D 398 SSF EMSQ GFS +G L VG+YDW G V + M D Sbjct: 366 SSFGLEMSQIGFSTHRLKDGILFGMVGAYDWGGSVLWLEGGHRLFPPRMALEDEFPPALQ 425 Query: 399 MNDAYLGYA-AAIILRNRVQSLVLGAPRYQHIGLVAMFR-QNTGMWESNANVKGTQIGAY 456 + AYLGY+ ++++LR + + GAPR++H G V F+ + G +++G QIG+Y Sbjct: 426 NHAAYLGYSVSSMLLRGGRRLFLSGAPRFRHRGKVIAFQLKKDGAVRVAQSLQGEQIGSY 485 Query: 457 FGASLCSVDVDSNGSTDLVLIGAPHYY--EQTRGGQVSVCPLPRGRARWQCDAVLYGEQG 514 FG+ LC +D D +G+TD++L+ AP + + G+V V L ++ L E Sbjct: 486 FGSELCPLDTDRDGTTDVLLVAAPMFLGPQNKETGRVYVY-LVGQQSLLTLQGTLQPEPP 544 Query: 515 QPWGRFGAALTVLGDVNGDKLTDVAIGAPGEEDNRGAVYLFHGTSGSGISPSHSQRIAGS 574 Q RFG A+ L D+N D DVA+GAP E+ ++GA+YL+HGT SG+ P +QRIA + Sbjct: 545 QD-ARFGFAMGALPDLNQDGFADVAVGAPLEDGHQGALYLYHGTQ-SGVRPHPAQRIAAA 602 Query: 575 KLSPRLQYFGQSLSGGQDLTMDGLVDLTVGAQGHVLLLRSQPVLRVKAIMEFNPREVARN 634 + L YFG+S+ G DL D LVD+ VGAQG +LL S+P++ + +E P+ ++ Sbjct: 603 SMPHALSYFGRSVDGRLDLDGDDLVDVAVGAQGAAILLSSRPIVHLTPSLEVTPQAISVV 662 Query: 635 VFECNDQVVKGKEAGEVRVCLHVQKSTRDRLREGQIQSVVTYDLALDSGRPHSRAVFNET 694 +C +G+EA + L Q ++R R Q + + +LD +RA F+ + Sbjct: 663 QRDCRR---RGQEAVCLTAALCFQVTSRTPGRWDH-QFYMRFTASLDEWTAGARAAFDGS 718 Query: 695 --KNSTRRQTQVLGLTQTCETLKLQLPNCIEDPVSPIVLRLNFSLVGTPLSAFGNLRPVL 752 + S RR +G TCE L + + D + P+ L + F+L T PVL Sbjct: 719 GQRLSPRRLRLSVG-NVTCEQLHFHVLDT-SDYLRPVALTVTFALDNTTKPG-----PVL 771 Query: 753 AEDAQRLFTALFPFEKNCGNDNICQDDLSITFSF-----MSLDCLVVGGPREFNVTVTVR 807 E + L PF K+CG DN C DL + + +V GG R+ V+ T+ Sbjct: 772 NEGSPTSIQKLVPFSKDCGPDNECVTDLVLQVNMDIRGSRKAPFVVRGGRRKVLVSTTLE 831 Query: 808 NDGEDSYRTQVTFFFPLDLSYRKVSTLQNQRSQRSWRLACESASSTEVSGALKSTSCSIN 867 N E++Y T ++ F +L +++L QR + ++ C + S+ + CS+ Sbjct: 832 NRKENAYNTSLSLIFSRNLH---LASLTPQR-ESPIKVECAAPSA-------HARLCSVG 880 Query: 868 HPIFPENSEVTFNITFDVDSKASLGNKLLLKANVTS---ENNMPRTNKTEFQLELPVKYA 924 HP+F ++VTF + F+ S +SL +++ +K +S E N + T Q ++Y Sbjct: 881 HPVFQTGAKVTFLLEFEF-SCSSLLSQVFVKLTASSDSLERNGTLQDNTA-QTSAYIQYE 938 Query: 925 VYMVVTSHGVSTKYLNF---TASENTSRVMQHQYQVSNLGQRSLP-ISLVFLVPVRLNQT 980 +++ +S +Y T + +V NLG + + + L+P + Sbjct: 939 PHLLFSSESTLHRYEVHPYGTLPVGPGPEFKTTLRVQNLGCYVVSGLIISALLPAVAHGG 998 Query: 981 VIWDRPQVTFSENLSSTCHTKERLPSHSDFLAELRKAPVVNCSIAVCQRIQCDIPFFGIQ 1040 + + N S P EL+ +N S CQ ++C + Sbjct: 999 NYFLSLSQVITNNASCIVQNLTEPPGPPVHPEELQHTNRLNGSNTQCQVVRCHLGQLAKG 1058 Query: 1041 EEFNATLKGNLSFDWYIKTSHNHLLIVSTAEILFNDSVFTLLPGQGAFVRSQTETKVEPF 1100 E + L + +++ + L +VST E+ + L + S E V+ Sbjct: 1059 TEVSVGLLRLVHNEFFRRAKFKSLTVVSTFELGTEEGSVLQLTEASRWSESLLEV-VQTR 1117 Query: 1101 EVPNPLPLIVGSSVGGLLLLALITAALYKLGFF 1133 + L +++GS +GGLLLLAL+ L+KLGFF Sbjct: 1118 PILISLWILIGSVLGGLLLLALLVFCLWKLGFF 1150 >gi|116295258 integrin alpha 2 precursor [Homo sapiens] Length = 1181 Score = 373 bits (957), Expect = e-103 Identities = 334/1200 (27%), Positives = 541/1200 (45%), Gaps = 127/1200 (10%) Query: 11 LTLCHGFNLDTENAMTFQ-ENARGFGQSVVQL---QGSRVVVGAPQEIVAANQRGSLYQC 66 L C +N+ A F ++ FG +V Q +G+ ++VG+P N+ G +Y+C Sbjct: 24 LNCCLAYNVGLPEAKIFSGPSSEQFGYAVQQFINPKGNWLLVGSPWSGFPENRMGDVYKC 83 Query: 67 --DYSTGSCEPIRLQVPVEA-------VNMSLGLSLAATTSPPQLLACGPTVHQTCSENT 117 D ST +CE + LQ NMSLGL L L CGP Q C Sbjct: 84 PVDLSTATCEKLNLQTSTSIPNVTEMKTNMSLGLILTRNMGTGGFLTCGPLWAQQCGNQY 143 Query: 118 YVKGLCFLFGSNLRQQPQKFPEALRGCPQEDSDIAFLIDGSGSIIPHDFRRMKEFVSTVM 177 Y G+C + Q F A + CP D+ + D S SI P D +K F+ + Sbjct: 144 YTTGVCSDISPDF-QLSASFSPATQPCPSL-IDVVVVCDESNSIYPWD--AVKNFLEKFV 199 Query: 178 EQLK--KSKTLFSLMQYSEEFRIHFTFKEFQNNPNPRSLVKPITQLLGR-THTATGIRKV 234 + L +KT L+QY+ R+ F ++ +Q G T+T I+ Sbjct: 200 QGLDIGPTKTQVGLIQYANNPRVVFNLNTYKTKEEMIVATSQTSQYGGDLTNTFGAIQYA 259 Query: 235 VRELFNITNGARKNAFKILVVITDGEKFGDPLGYEDVIPEADREGVIRYVIGV-----GD 289 + ++ +G R++A K++VV+TDGE + + VI + + + ++R+ I V + Sbjct: 260 RKYAYSAASGGRRSATKVMVVVTDGESHDGSM-LKAVIDQCNHDNILRFGIAVLGYLNRN 318 Query: 290 AFRSEKSRQELNTIASKPPRDHVFQVNNFEALKTIQNQLREKIFAIEGTQTGSSSSFEHE 349 A ++ +E+ IAS P + F V++ AL L E+IF+IEGT G + F+ E Sbjct: 319 ALDTKNLIKEIKAIASIPTERYFFNVSDEAALLEKAGTLGEQIFSIEGTVQGGDN-FQME 377 Query: 350 MSQEGFSAAITSNGPLL--STVGSYDWAGGVFLYTSKEKSTFINMT--RVDSDMN-DAYL 404 MSQ GFSA +S +L VG++ W+G + TS F ++ D N +YL Sbjct: 378 MSQVGFSADYSSQNDILMLGAVGAFGWSGTIVQKTSHGHLIFPKQAFDQILQDRNHSSYL 437 Query: 405 GYAAAIILRNRVQSLVLGAPRYQHIGLVAMFRQNTGMWESNANV------KGTQIGAYFG 458 GY+ A I V GAPR + G + ++ N N N+ +G QIG+YFG Sbjct: 438 GYSVAAISTGESTHFVAGAPRANYTGQIVLYSVN-----ENGNITVIQAHRGDQIGSYFG 492 Query: 459 ASLCSVDVDSNGSTDLVLIGAPHYYEQTRG--GQVSVCPLPRGRARWQCDAVLYGEQGQP 516 + LCSVDVD + TD++L+GAP Y + G+V + + G L G +G Sbjct: 493 SVLCSVDVDKDTITDVLLVGAPMYMSDLKKEEGRVYLFTIKEGILGQH--QFLEGPEGIE 550 Query: 517 WGRFGAALTVLGDVNGDKLTDVAIGAPGEEDNRGAVYLFHGTSGSGISPSHSQRIAGSKL 576 RFG+A+ L D+N D DV +G+P E N GAVY+++G G+ I +SQ+I GS Sbjct: 551 NTRFGSAIAALSDINMDGFNDVIVGSPLENQNSGAVYIYNGHQGT-IRTKYSQKILGSDG 609 Query: 577 SPR--LQYFGQSLSGGQDLTMDGLVDLTVGAQGHVLLLRSQPVLRVKAIMEFNPREVARN 634 + R LQYFG+SL G DL D + D+++GA G V+ L SQ + V F P ++ Sbjct: 610 AFRSHLQYFGRSLDGYGDLNGDSITDVSIGAFGQVVQLWSQSIADVAIEASFTPEKIT-- 667 Query: 635 VFECNDQVVKGKEAGEVRVCLHVQKSTRDRLREGQIQSVVTYDLALD----SGRPHSRAV 690 + N Q++ +++C S + R + Q + Y++ LD S R SR + Sbjct: 668 LVNKNAQII-------LKLCF----SAKFRPTKQNNQVAIVYNITLDADGFSSRVTSRGL 716 Query: 691 FNETKNSTRRQTQVLGLTQTC--ETLKLQLPNCIEDPVSPIVLRLNFSLVGTPLSAFGNL 748 F E ++ V+ Q+C + +Q P+ D V+ + LR++ SL S Sbjct: 717 FKENNERCLQKNMVVNQAQSCPEHIIYIQEPS---DVVNSLDLRVDISLENPGTS----- 768 Query: 749 RPVLAEDAQRLFTALFPFEKNCGNDNICQDDLSITF----SFMSLDCLVVGGPREFNVTV 804 P L ++ PF K+CG D +C DL + + +V + +V Sbjct: 769 -PALEAYSETAKVFSIPFHKDCGEDGLCISDLVLDVRQIPAAQEQPFIVSNQNKRLTFSV 827 Query: 805 TVRNDGEDSYRTQVTFFFPLDLSYRKVSTLQNQRSQRSWRLACESASST-EVSGALKSTS 863 T++N E +Y T + F +L + S+ L + T +V+ + KS + Sbjct: 828 TLKNKRESAYNTGIVVDFSENLFFA------------SFSLPVDGTEVTCQVAASQKSVA 875 Query: 864 CSINHPIFPENSEVTFNITFDVDSKASLGNKLLLKANVTSENNMPRTNKTEFQLELPVKY 923 C + +P +VTF I FD + + +L N+ L SE+ L++P+ Y Sbjct: 876 CDVGYPALKREQQVTFTINFDFNLQ-NLQNQASLSFQALSESQEENKADNLVNLKIPLLY 934 Query: 924 AVYMVVTSHGVSTKYLNFTASENTSRVMQHQYQVSNLGQR---SLPISLVFLVPVRLNQT 980 + H + +NF + V + ++G + SL ++ VPV + T Sbjct: 935 DAEI----HLTRSTNINFYEISSDGNVPSIVHSFEDVGPKFIFSLKVT-TGSVPVSM-AT 988 Query: 981 VIWDRPQVTFSENL-------------SSTCHTK------ERLPSHSDFLAE-LRKAPVV 1020 VI PQ T +N +C+ + S F +E R + Sbjct: 989 VIIHIPQYTKEKNPLMYLTGVQTDKAGDISCNADINPLKIGQTSSSVSFKSENFRHTKEL 1048 Query: 1021 NCSIAVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYIKTSHNHLLIVSTAEILFNDSVFT 1080 NC A C + C + ++ E+ + + + ++ + + + AEI + Sbjct: 1049 NCRTASCSNVTCWLKDVHMKGEYFVNVTTRIWNGTFASSTFQTVQLTAAAEINTYNPEIY 1108 Query: 1081 LLPGQGAFVRSQTETKVEPFEVPNPLPLIVGSSVGGLLLLALITAALYKLGFFKRQYKDM 1140 ++ + E EVP + I+GS + G+LLL + A L+KLGFFKR+Y+ M Sbjct: 1109 VIEDNTVTIPLMIMKPDEKAEVPTGV--IIGSIIAGILLLLALVAILWKLGFFKRKYEKM 1166 >gi|52485941 integrin, alpha 9 precursor [Homo sapiens] Length = 1035 Score = 213 bits (541), Expect = 1e-54 Identities = 228/860 (26%), Positives = 386/860 (44%), Gaps = 99/860 (11%) Query: 347 EHEMSQEGFSAAITSNGPLLSTVGSYDWAGGVFLYTSKEKSTFINMTRVDSDMNDAYLGY 406 EH Q G + T ++ GS+ WAG + + + + V + YLGY Sbjct: 190 EHGSCQAGIAGFFTEELVVMGAPGSFYWAGTIKVLNLTDNTYLKLNDEVIMNRRYTYLGY 249 Query: 407 A--AAIILRNRVQSLVLGAPRYQHIGLVAMFR--QNTGMWESNANVKGTQIGAYFGASLC 462 A A +V GAP+ + IG V +FR + +G G ++G+YFG+SLC Sbjct: 250 AVTAGHFSHPSTIDVVGGAPQDKGIGKVYIFRADRRSGTLIKIFQASGKKMGSYFGSSLC 309 Query: 463 SVDVDSNGSTDLVLIGAPHYYEQTRGGQVSVCPLPRGRARWQCDAVLYGEQGQPWGRFGA 522 +VD++ +G +DL L+GAP + E GQV+V + RG + L G+ G FG Sbjct: 310 AVDLNGDGLSDL-LVGAPMFSEIRDEGQVTVY-INRGNGALEEQLALTGD-GAYNAHFGE 366 Query: 523 ALTVLGDVNGDKLTDVAIGAPGEEDNRGAVYLFHGTSGSGISPSHSQRIAGSKLSPRLQY 582 ++ L D++ D DVAIGAP E+D GAVY++HG +G GI P +S +++G K++P L+ Sbjct: 367 SIASLDDLDNDGFPDVAIGAPKEDDFAGAVYIYHGDAG-GIVPQYSMKLSGQKINPVLRM 425 Query: 583 FGQSLSGGQDLTMDGLVDLTVGA--QGHVLLLRSQPVLRVKAIMEFNPREVARNVFECND 640 FGQS+SGG D+ +G D+TVGA V+LLR++PV+ V + F P + +C+D Sbjct: 426 FGQSISGGIDMDGNGYPDVTVGAFMSDSVVLLRARPVITVD-VSIFLPGSINITAPQCHD 484 Query: 641 QVVKGKEAGEVRV-CLHVQK--STRDRLREGQI--QSVVTYDLALDSGRPHSRAVF---N 692 G+ V CL+V S + G+I V+ D+A R F Sbjct: 485 --------GQQPVNCLNVTTCFSFHGKHVPGEIGLNYVLMADVAKKEKGQMPRVYFVLLG 536 Query: 693 ETKNSTRRQTQVLGLTQTCETLKLQLPNCIEDPVSPIVLRLNFSL----VGTPLSAFGNL 748 ET + Q+ + +TC + ++D +SPIV +SL G L Sbjct: 537 ETMGQVTEKLQLTYMEETCRHYVAHVKRRVQDVISPIVFEAAYSLSEHVTGEEERELPPL 596 Query: 749 RPVL-----AEDAQRLFTALFPFEKNCGNDNICQDDLSITFSFM--SLD----CLVVGGP 797 PVL + AQ+ T FE+NC +++ C DL + + S+D L +G Sbjct: 597 TPVLRWKKGQKIAQKNQTV---FERNCRSED-CAADLQLQGKLLLSSMDEKTLYLALGAV 652 Query: 798 REFNVTVTVRNDGEDSYRTQVTFFFPLDLSYRKVSTLQNQRSQRSWRLACESASSTEVSG 857 + ++ +++ N G+D+Y V+F +L + N + ++CE S + Sbjct: 653 KNISLNISISNLGDDAYDANVSFNVSRELFF------INMWQKEEMGISCELLESDFL-- 704 Query: 858 ALKSTSCSINHPIFPENSEVTFNITFDVDSKASLGNKLLLKANVTSEN-NMPRT---NKT 913 CS+ P S+ F++ FD + G + +L VT+++ N R+ + Sbjct: 705 -----KCSVGFPFMRSKSKYEFSVIFDTSHLS--GEEEVLSFIVTAQSGNTERSESLHDN 757 Query: 914 EFQLELPVKYAVYMVVTS--------HGVSTKYLNFTASENTS---RVMQHQYQVSNLGQ 962 L +P+ + V +T +G S NF ++ + + QV N G Sbjct: 758 TLVLMVPLMHEVDTSITGIMSPTSFVYGESVDAANFIQLDDLECHFQPINITLQVYNTGP 817 Query: 963 RSLPISLVFL-VPVRLN-----------QTVIWDRPQVTFSENLSSTCHTKERLPSHSDF 1010 +LP S V + P RL+ V ++ +F +N + +E+ Sbjct: 818 STLPGSSVSISFPNRLSSGGAEMFHVQEMVVGQEKGNCSFQKNPTPCIIPQEQENIFHTI 877 Query: 1011 LAELRKA--PVVNCSI--AVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYIKTSHNHLLI 1066 A K+ V++C C C+ +E + L+ + K S + + Sbjct: 878 FAFFTKSGRKVLDCEKPGISCLTAHCNFSALAKEESRTIDIYMLLNTEILKKDSSSVIQF 937 Query: 1067 VSTAEILFNDSVFTLLPGQGAFVRSQTETKVEPFEVPNPLPLIVG-----SSVGGLLLLA 1121 +S A++ + ++ + G + E P +VG S + G+L+ Sbjct: 938 MSRAKVKVDPALRVVEIAHGN--PEEVTVVFEALHNLEPRGYVVGWIIAISLLVGILIFL 995 Query: 1122 LITAALYKLGFFKRQYKDMM 1141 L+ L+K+GFF+R+YK+++ Sbjct: 996 LLAVLLWKMGFFRRRYKEII 1015 >gi|67191027 integrin alpha 4 precursor [Homo sapiens] Length = 1032 Score = 212 bits (539), Expect = 2e-54 Identities = 224/862 (25%), Positives = 366/862 (42%), Gaps = 115/862 (13%) Query: 352 QEGFSAAITSNGPLLSTVGSYDWAGGVFLY---TSKEKSTFINMTRVDSDMNDAYLGYA- 407 Q G S+ T + ++ GS W G +F+Y T+K K+ +V +YLGY+ Sbjct: 199 QAGISSFYTKDLIVMGAPGSSYWTGSLFVYNITTNKYKAFLDKQNQVKFG---SYLGYSV 255 Query: 408 -AAIILRNRVQSLVLGAPRYQHIGLVAMFRQNTGMWESNANVKGTQIGAYFGASLCSVDV 466 A +V GAP+++ IG +F + +KG ++G+YFGAS+C+VD+ Sbjct: 256 GAGHFRSQHTTEVVGGAPQHEQIGKAYIFSIDEKELNILHEMKGKKLGSYFGASVCAVDL 315 Query: 467 DSNGSTDLVLIGAPHYYEQTRGGQVSV-CPLPRGRARWQCDAVLYGEQGQPWGRFGAALT 525 +++G +DL L+GAP G+V V G + L G RFG ++ Sbjct: 316 NADGFSDL-LVGAPMQSTIREEGRVFVYINSGSGAVMNAMETNLVGSDKYA-ARFGESIV 373 Query: 526 VLGDVNGDKLTDVAIGAPGEEDNRGAVYLFHGTSGSGISPSHSQRIAGSKLSPRLQYFGQ 585 LGD++ D DVAIGAP E+D +GA+Y+++G + GIS + SQRI G ++S L FGQ Sbjct: 374 NLGDIDNDGFEDVAIGAPQEDDLQGAIYIYNGRA-DGISSTFSQRIEGLQISKSLSMFGQ 432 Query: 586 SLSGGQDLTMDGLVDLTVGA--QGHVLLLRSQPVLRVKAIMEFNPREVARNVFECNDQVV 643 S+SG D +G VD+ VGA +LLR++PV+ V A + +P V R F+C Sbjct: 433 SISGQIDADNNGYVDVAVGAFRSDSAVLLRTRPVVIVDASLS-HPESVNRTKFDC----- 486 Query: 644 KGKEAGEVRVCLHVQKSTRDRLREGQIQSVVTYDLALDSGR-----PHSRAVFNETKNST 698 E G VC+ + + +E V+ Y+++LD R P N T + Sbjct: 487 --VENGWPSVCIDLTLCFSYKGKEVPGYIVLFYNMSLDVNRKAESPPRFYFSSNGTSDVI 544 Query: 699 RRQTQVLGLTQTCETLKLQLPNCIEDPVSPIVLRLNFSLVGTPLS-----AFGNLRPVLA 753 QV C T + + + D ++PI + + L +S F L+P+L Sbjct: 545 TGSIQVSSREANCRTHQAFMRKDVRDILTPIQIEAAYHLGPHVISKRSTEEFPPLQPILQ 604 Query: 754 EDAQR-LFTALFPFEKNCGNDNICQDDLSITFSFMSL------DCLVVGGPREFNVTVTV 806 + ++ + F + C ++N C DL ++ L L VG + + V++ Sbjct: 605 QKKEKDIMKKTINFARFCAHEN-CSADLQVSAKIGFLKPHENKTYLAVGSMKTLMLNVSL 663 Query: 807 RNDGEDSYRTQVTFFFPLDLSYRKVSTLQNQRSQRSWRLACESASSTEVSGALKSTSCSI 866 N G+D+Y T + P+ L + K+ L+ + ++ CE T+ SG ++ CSI Sbjct: 664 FNAGDDAYETTLHVKLPVGLYFIKILELEEK------QINCE---VTDNSGVVQ-LDCSI 713 Query: 867 NHPIFPENSEVTFNITFDVDSKASLGNKLLLKANVTSEN--NMPRTNKTEFQLELPVKYA 924 + S + + DV S + L + + T EN M + + +P+KY Sbjct: 714 GYIYVDHLSRIDISFLLDVSSLSRAEEDLSITVHATCENEEEMDNLKHSRVTVAIPLKYE 773 Query: 925 VYMVVTSHGVSTKYLNFTASENTSRV-----MQHQYQVSNLGQRSLP-ISLVFLVPVRLN 978 V + V T ++ + EN M + V N G P +S+ +VP + Sbjct: 774 VKLTVHGFVNPTSFVYGSNDENEPETCMVEKMNLTFHVINTGNSMAPNVSVEIMVPNSFS 833 Query: 979 QTV-----IWDRPQVT---FSENLSSTCHTKERLPSHSDFLAELRKAPVVNCSIAVCQRI 1030 I D T EN C +++ + +R + + C I Sbjct: 834 PQTDKLFNILDVQTTTGECHFENYQRVCALEQQKSAMQTLKGIVRFLSKTDKRLLYC--I 891 Query: 1031 QCDIPFFGIQEEFNATLKGNLSFDWYIKTSHNHLLIVSTAEILFNDSVFTLLPGQGAFVR 1090 + D F G K + H+ + IL D L Sbjct: 892 KADPHCLNFLCNFGKMESG--------KEASVHIQLEGRPSILEMDETSAL--------- 934 Query: 1091 SQTETKVEPFEVPNP-----------------------------LPLIVGSSVGGLLLLA 1121 + E + F PNP + +I S + GL++L Sbjct: 935 -KFEIRATGFPEPNPRVIELNKDENVAHVLLEGLHHQRPKRYFTIVIISSSLLLGLIVLL 993 Query: 1122 LITAALYKLGFFKRQYKDMMSE 1143 LI+ ++K GFFKRQYK ++ E Sbjct: 994 LISYVMWKAGFFKRQYKSILQE 1015 Score = 33.5 bits (75), Expect = 1.2 Identities = 39/144 (27%), Positives = 59/144 (40%), Gaps = 14/144 (9%) Query: 462 CSVDVDSNGSTDLVLIGAPHYYEQTRGGQVSVCPLPRGRARWQCDAVLYGEQGQPWGRFG 521 C + S + DL+++GAP T G + V + + + A L + +G + Sbjct: 198 CQAGISSFYTKDLIVMGAPGSSYWT--GSLFVYNITTNKYK----AFLDKQNQVKFGSYL 251 Query: 522 AALTVLGDVNGDKLTDVAIGAPGEEDNRGAVYLFHGTSGSGISPSHSQRIAGSKLSPRLQ 581 G T+V GAP + + G Y+F ++ H + G KL Sbjct: 252 GYSVGAGHFRSQHTTEVVGGAP-QHEQIGKAYIF-SIDEKELNILHEMK--GKKLG---S 304 Query: 582 YFGQSLSGGQDLTMDGLVDLTVGA 605 YFG S+ DL DG DL VGA Sbjct: 305 YFGASVC-AVDLNADGFSDLLVGA 327 Score = 32.7 bits (73), Expect = 2.0 Identities = 44/159 (27%), Positives = 71/159 (44%), Gaps = 27/159 (16%) Query: 5 VLLLTALTLCHG--FNLDTENAMTFQ-ENARGFGQSVV-QLQGSR--VVVGAPQEIVAAN 58 V+LL L + G +N+DTE+A+ +Q + FG SVV G+ ++VGAP AN Sbjct: 20 VMLLLCLGVPTGRPYNVDTESALLYQGPHNTLFGYSVVLHSHGANRWLLVGAPTANWLAN 79 Query: 59 ----QRGSLYQCDYSTG---SCEPIRLQVP----------VEAVNMSLGLSLAATTSP-P 100 G++Y+C +CE ++L P E N LG++L+ Sbjct: 80 ASVINPGAIYRCRIGKNPGQTCEQLQLGSPNGEPCGKTCLEERDNQWLGVTLSRQPGENG 139 Query: 101 QLLACG---PTVHQTCSENTYVKGLCFLFGSNLRQQPQK 136 ++ CG + +EN G C+ +LR + K Sbjct: 140 SIVTCGHRWKNIFYIKNENKLPTGGCYGVPPDLRTELSK 178 >gi|223468595 integrin alpha-V isoform 2 [Homo sapiens] Length = 1002 Score = 168 bits (426), Expect = 2e-41 Identities = 204/861 (23%), Positives = 362/861 (42%), Gaps = 100/861 (11%) Query: 352 QEGFSAAIT-SNGPLLSTVGSYDWAGGVF--------------LYTSKEKSTFINMTRVD 396 Q GFS T ++ LL GS+ W G + +Y+ K + T Sbjct: 140 QGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPNVYSIKYNNQLATRT-AQ 198 Query: 397 SDMNDAYLGYAAAI--ILRNRVQSLVLGAPRYQH-IGLVAMFRQNTGMWESNANVKGTQI 453 + +D+YLGY+ A+ + + V G PR +G+V ++ S N G Q+ Sbjct: 199 AIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKN--MSSLYNFTGEQM 256 Query: 454 GAYFGASLCSVDVDSNGSTDLVLIGAPHYYEQTRGG------QVSVCPLPRGRARWQCDA 507 AYFG S+ + D++ + D V IGAP + ++ G QVSV L R +Q Sbjct: 257 AAYFGFSVAATDINGDDYAD-VFIGAPLFMDRGSDGKLQEVGQVSVS-LQRASGDFQTTK 314 Query: 508 VLYGEQGQPWGRFGAALTVLGDVNGDKLTDVAIGAP-GEEDNRGAVYLFHGTSGSGISPS 566 + + + RFG+A+ LGD++ D D+AI AP G ED +G VY+F+G S +G++ Sbjct: 315 L---NGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRS-TGLNAV 370 Query: 567 HSQRIAGSKLSPRL-QYFGQSLSGGQDLTMDGLVDLTVGAQG--HVLLLRSQPVLRVKAI 623 SQ + G + + FG S+ G D+ +G DL VGA G +L R++PV+ V A Sbjct: 371 PSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAG 430 Query: 624 MEFNPREVARNVFECNDQVVKGK-EAGEVRVCLHVQ-KSTRDRLREGQIQSVVTYDLALD 681 +E P + ++ C+ K VR CL K R Q++ ++ L Sbjct: 431 LEVYPSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLD-KLKQK 489 Query: 682 SGRPHSRAVFNETKNSTRRQTQVLGLTQTCETLKLQLPNCIE--DPVSPIVLRLNFSLVG 739 + +++ + + ++ T G CE L L + E D ++PI + + + L Sbjct: 490 GAIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEYRLDY 549 Query: 740 TPLSAFGNLRPVLAEDAQRLFTALFPFEKNCGNDNICQDDLSITFSFMSLDCLVVGGPRE 799 + L+P+L + + +CG DN+C+ L ++ + +G Sbjct: 550 RTAADTTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVD-SDQKKIYIGDDNP 608 Query: 800 FNVTVTVRNDGEDSYRTQVTFFFPLDLSYRKVSTLQNQRSQRSWRLACESASSTEVSGAL 859 + V +N GE +Y ++ PL + + ++N + RL+C A TE Sbjct: 609 LTLIVKAQNQGEGAYEAELIVSIPLQADF--IGVVRNNEALA--RLSC--AFKTE--NQT 660 Query: 860 KSTSCSINHPIFPENSEVTFNITFDVDSKASLGNKLLLKANVTSENNMPRTNKTEFQLEL 919 + C + +P+ +++ + F V ++ + + + S N + + + Sbjct: 661 RQVVCDLGNPM-KAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPV---VSH 716 Query: 920 PVKYAVYMVVTSHGVSTK---YL---------NFTASENTSRVMQHQYQVSNLGQRSLPI 967 V AV V GVS+ +L N E+ V+QH Y++ N G S Sbjct: 717 KVDLAVLAAVEIRGVSSPDHIFLPIPNWEHKENPETEEDVGPVVQHIYELRNNGPSSFSK 776 Query: 968 SLVFLV-PVRLNQTVIW-------DRP-------------------QVTFSENLSSTCHT 1000 +++ L P + N + D P Q T + + Sbjct: 777 AMLHLQWPYKYNNNTLLYILHYDIDGPMNCTSDMEINPLRIKISSLQTTEKNDTVAGQGE 836 Query: 1001 KERLPSHSDFLAELRKAPVVNCSIAVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYI-KT 1059 ++ L + D + C +A C +I C + + +K L + ++ K Sbjct: 837 RDHLITKRDLALSEGDIHTLGCGVAQCLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKE 896 Query: 1060 SHNH-LLIVSTAEILFNDSVFTLLP----GQGAFVRSQTETKVEPFEVPNPLPLIVGSSV 1114 + NH + S+A + + LP V + ++P +P P+ +I+ + + Sbjct: 897 NQNHSYSLKSSASFNVIEFPYKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVL 956 Query: 1115 GGLLLLALITAALYKLGFFKR 1135 GLLLLA++ +Y++GFFKR Sbjct: 957 AGLLLLAVLVFVMYRMGFFKR 977 >gi|4504763 integrin alpha-V isoform 1 precursor [Homo sapiens] Length = 1048 Score = 168 bits (426), Expect = 2e-41 Identities = 204/861 (23%), Positives = 362/861 (42%), Gaps = 100/861 (11%) Query: 352 QEGFSAAIT-SNGPLLSTVGSYDWAGGVF--------------LYTSKEKSTFINMTRVD 396 Q GFS T ++ LL GS+ W G + +Y+ K + T Sbjct: 186 QGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPNVYSIKYNNQLATRT-AQ 244 Query: 397 SDMNDAYLGYAAAI--ILRNRVQSLVLGAPRYQH-IGLVAMFRQNTGMWESNANVKGTQI 453 + +D+YLGY+ A+ + + V G PR +G+V ++ S N G Q+ Sbjct: 245 AIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKN--MSSLYNFTGEQM 302 Query: 454 GAYFGASLCSVDVDSNGSTDLVLIGAPHYYEQTRGG------QVSVCPLPRGRARWQCDA 507 AYFG S+ + D++ + D V IGAP + ++ G QVSV L R +Q Sbjct: 303 AAYFGFSVAATDINGDDYAD-VFIGAPLFMDRGSDGKLQEVGQVSVS-LQRASGDFQTTK 360 Query: 508 VLYGEQGQPWGRFGAALTVLGDVNGDKLTDVAIGAP-GEEDNRGAVYLFHGTSGSGISPS 566 + + + RFG+A+ LGD++ D D+AI AP G ED +G VY+F+G S +G++ Sbjct: 361 L---NGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRS-TGLNAV 416 Query: 567 HSQRIAGSKLSPRL-QYFGQSLSGGQDLTMDGLVDLTVGAQG--HVLLLRSQPVLRVKAI 623 SQ + G + + FG S+ G D+ +G DL VGA G +L R++PV+ V A Sbjct: 417 PSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAG 476 Query: 624 MEFNPREVARNVFECNDQVVKGK-EAGEVRVCLHVQ-KSTRDRLREGQIQSVVTYDLALD 681 +E P + ++ C+ K VR CL K R Q++ ++ L Sbjct: 477 LEVYPSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLD-KLKQK 535 Query: 682 SGRPHSRAVFNETKNSTRRQTQVLGLTQTCETLKLQLPNCIE--DPVSPIVLRLNFSLVG 739 + +++ + + ++ T G CE L L + E D ++PI + + + L Sbjct: 536 GAIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEYRLDY 595 Query: 740 TPLSAFGNLRPVLAEDAQRLFTALFPFEKNCGNDNICQDDLSITFSFMSLDCLVVGGPRE 799 + L+P+L + + +CG DN+C+ L ++ + +G Sbjct: 596 RTAADTTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVD-SDQKKIYIGDDNP 654 Query: 800 FNVTVTVRNDGEDSYRTQVTFFFPLDLSYRKVSTLQNQRSQRSWRLACESASSTEVSGAL 859 + V +N GE +Y ++ PL + + ++N + RL+C A TE Sbjct: 655 LTLIVKAQNQGEGAYEAELIVSIPLQADF--IGVVRNNEALA--RLSC--AFKTE--NQT 706 Query: 860 KSTSCSINHPIFPENSEVTFNITFDVDSKASLGNKLLLKANVTSENNMPRTNKTEFQLEL 919 + C + +P+ +++ + F V ++ + + + S N + + + Sbjct: 707 RQVVCDLGNPM-KAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPV---VSH 762 Query: 920 PVKYAVYMVVTSHGVSTK---YL---------NFTASENTSRVMQHQYQVSNLGQRSLPI 967 V AV V GVS+ +L N E+ V+QH Y++ N G S Sbjct: 763 KVDLAVLAAVEIRGVSSPDHIFLPIPNWEHKENPETEEDVGPVVQHIYELRNNGPSSFSK 822 Query: 968 SLVFLV-PVRLNQTVIW-------DRP-------------------QVTFSENLSSTCHT 1000 +++ L P + N + D P Q T + + Sbjct: 823 AMLHLQWPYKYNNNTLLYILHYDIDGPMNCTSDMEINPLRIKISSLQTTEKNDTVAGQGE 882 Query: 1001 KERLPSHSDFLAELRKAPVVNCSIAVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYI-KT 1059 ++ L + D + C +A C +I C + + +K L + ++ K Sbjct: 883 RDHLITKRDLALSEGDIHTLGCGVAQCLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKE 942 Query: 1060 SHNH-LLIVSTAEILFNDSVFTLLP----GQGAFVRSQTETKVEPFEVPNPLPLIVGSSV 1114 + NH + S+A + + LP V + ++P +P P+ +I+ + + Sbjct: 943 NQNHSYSLKSSASFNVIEFPYKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVL 1002 Query: 1115 GGLLLLALITAALYKLGFFKR 1135 GLLLLA++ +Y++GFFKR Sbjct: 1003 AGLLLLAVLVFVMYRMGFFKR 1023 Score = 31.6 bits (70), Expect = 4.5 Identities = 36/137 (26%), Positives = 54/137 (39%), Gaps = 23/137 (16%) Query: 11 LTLCHGFNLDTENAMTFQ-ENARGFGQSV---VQLQGSR--VVVGAPQEIVAAN---QRG 61 L LC FNLD ++ + FG +V V SR ++VGAP+ + G Sbjct: 25 LPLCRAFNLDVDSPAEYSGPEGSYFGFAVDFFVPSASSRMFLLVGAPKANTTQPGIVEGG 84 Query: 62 SLYQCDY-STGSCEPIRLQV----------PVEAVNMSLGLSLAATTSPPQLLACGPTVH 110 + +CD+ ST C+PI P+E + + ++LAC P H Sbjct: 85 QVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLE-FKSHQWFGASVRSKQDKILACAPLYH 143 Query: 111 --QTCSENTYVKGLCFL 125 + G CFL Sbjct: 144 WRTEMKQEREPVGTCFL 160 >gi|56237029 integrin alpha 5 precursor [Homo sapiens] Length = 1049 Score = 168 bits (425), Expect = 3e-41 Identities = 222/862 (25%), Positives = 366/862 (42%), Gaps = 117/862 (13%) Query: 352 QEGFSAAITSNGPL-LSTVGSYDWAGGVFLYTSKEKST------FINMTR-------VDS 397 Q GFSA T G + L GSY W G + T ++ + IN+ + S Sbjct: 206 QGGFSAEFTKTGRVVLGGPGSYFWQGQILSATQEQIAESYYPEYLINLVQGQLQTRQASS 265 Query: 398 DMNDAYLGYAAAI--ILRNRVQSLVLGAPR----YQHIGLVAMFRQNTGMWESNANVKGT 451 +D+YLGY+ A+ + + V G P+ Y ++ ++ N S N G Sbjct: 266 IYDDSYLGYSVAVGEFSGDDTEDFVAGVPKGNLTYGYVTIL-----NGSDIRSLYNFSGE 320 Query: 452 QIGAYFGASLCSVDVDSNGSTDLVLIGAPHYYEQTRGGQVSVCPLPRGR--------ARW 503 Q+ +YFG ++ + DV+ +G DL L+GAP ++T G+ P GR A Sbjct: 321 QMASYFGYAVAATDVNGDGLDDL-LVGAPLLMDRTPDGR----PQEVGRVYVYLQHPAGI 375 Query: 504 QCDAVLYGEQGQPWGRFGAALTVLGDVNGDKLTDVAIGAP-GEEDNRGAVYLF-HGTSGS 561 + L +GRFG++LT LGD++ D DVAIGAP G E +G V++F G G Sbjct: 376 EPTPTLTLTGHDEFGRFGSSLTPLGDLDQDGYNDVAIGAPFGGETQQGVVFVFPGGPGGL 435 Query: 562 GISPSH-SQRIAGSKLSPRLQYFGQSLSGGQDLTMDGLVDLTVGAQG--HVLLLRSQPVL 618 G PS Q + + +P +FG +L GG+DL +G DL VG+ G ++ R +P++ Sbjct: 436 GSKPSQVLQPLWAASHTP--DFFGSALRGGRDLDGNGYPDLIVGSFGVDKAVVYRGRPIV 493 Query: 619 RVKAIME-----FNPREVARNVFECNDQVVKGKEAGEVRVCLHVQKSTRDRLREGQIQSV 673 A + FNP E + ++ G C+++ + Sbjct: 494 SASASLTIFPAMFNPEERSCSL------------EGNPVACINLSFCLNASGKHVADSIG 541 Query: 674 VTYDLALDSGRPHS---RAVFNETKNSTRRQTQVL--GLTQTCETLKLQLPNCIE--DPV 726 T +L LD + RA+F ++ +T QT ++ G + C +K+ L N E D + Sbjct: 542 FTVELQLDWQKQKGGVRRALFLASRQATLTQTLLIQNGAREDCREMKIYLRNESEFRDKL 601 Query: 727 SPIVLRLNFSL-VGTPLSAFGNLRPVLAEDAQRLFTALFPFEKNCGNDNICQDDLSITFS 785 SPI + LNFSL P+ + G LRP L ++ +CG DNIC DL + Sbjct: 602 SPIHIALNFSLDPQAPVDSHG-LRPALHYQSKSRIEDKAQILLDCGEDNICVPDLQLEV- 659 Query: 786 FMSLDCLVVGGPREFNVTVTVRNDGE-DSYRTQVTFFFPLDLSYRKVSTLQNQRSQRSWR 844 F + + +G N+T +N GE +Y ++ P + Y + S Sbjct: 660 FGEQNHVYLGDKNALNLTFHAQNVGEGGAYEAELRVTAPPEAEYSGLVRHPGNFSS---- 715 Query: 845 LACESASSTEVSGALKSTSCSINHPIFPENSEVTFNITFDVDSKASLGNKLLLKANVTSE 904 L+C+ + + + C + +P+ + + + F V + + S+ Sbjct: 716 LSCDYFAVNQ----SRLLVCDLGNPM-KAGASLWGGLRFTVPHLRDTKKTIQFDFQILSK 770 Query: 905 N-NMPRTNKTEFQLELPVKYAVYMVVTSHGVS-TKYLNFTAS-----------ENTSRVM 951 N N +++ F+L + + VT +GVS + + F S E+ + Sbjct: 771 NLNNSQSDVVSFRLSVEAQ----AQVTLNGVSKPEAVLFPVSDWHPRDQPQKEEDLGPAV 826 Query: 952 QHQYQVSNLGQRSLPISLVFL-VPVRLNQTVIWDRPQVT---FSENLSSTCHTKERLPSH 1007 H Y++ N G S+ ++ L P L + +VT + N E P Sbjct: 827 HHVYELINQGPSSISQGVLELSCPQALEGQQLLYVTRVTGLNCTTNHPINPKGLELDPEG 886 Query: 1008 SDFLAELRKAP----------VVNCSIAVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYI 1057 S + R+AP ++ C A C R++C++ QE + L + ++ Sbjct: 887 SLHHQQKREAPSRSSASSGPQILKCPEAECFRLRCELGPLHQQESQSLQLHFRVWAKTFL 946 Query: 1058 KTSHNHLLIVSTAEILFNDSVFTLLPGQGAFVRSQTETKVEPFEVPN----PLPLIVGSS 1113 + H + A + +LP Q Q T V+ + PL +I+ + Sbjct: 947 QREHQPFSLQCEAVYKALKMPYRILPRQLPQKERQVATAVQWTKAEGSYGVPLWIIILAI 1006 Query: 1114 VGGLLLLALITAALYKLGFFKR 1135 + GLLLL L+ LYKLGFFKR Sbjct: 1007 LFGLLLLGLLIYILYKLGFFKR 1028 >gi|223468597 integrin alpha-V isoform 3 precursor [Homo sapiens] Length = 1012 Score = 164 bits (416), Expect = 3e-40 Identities = 190/798 (23%), Positives = 340/798 (42%), Gaps = 84/798 (10%) Query: 400 NDAYLGYAAAI--ILRNRVQSLVLGAPRYQH-IGLVAMFRQNTGMWESNANVKGTQIGAY 456 +D+YLGY+ A+ + + V G PR +G+V ++ S N G Q+ AY Sbjct: 212 DDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKN--MSSLYNFTGEQMAAY 269 Query: 457 FGASLCSVDVDSNGSTDLVLIGAPHYYEQTRGG------QVSVCPLPRGRARWQCDAVLY 510 FG S+ + D++ + D V IGAP + ++ G QVSV L R +Q + Sbjct: 270 FGFSVAATDINGDDYAD-VFIGAPLFMDRGSDGKLQEVGQVSVS-LQRASGDFQTTKL-- 325 Query: 511 GEQGQPWGRFGAALTVLGDVNGDKLTDVAIGAP-GEEDNRGAVYLFHGTSGSGISPSHSQ 569 + + RFG+A+ LGD++ D D+AI AP G ED +G VY+F+G S +G++ SQ Sbjct: 326 -NGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRS-TGLNAVPSQ 383 Query: 570 RIAGSKLSPRL-QYFGQSLSGGQDLTMDGLVDLTVGAQG--HVLLLRSQPVLRVKAIMEF 626 + G + + FG S+ G D+ +G DL VGA G +L R++PV+ V A +E Sbjct: 384 ILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAGLEV 443 Query: 627 NPREVARNVFECNDQVVKGK-EAGEVRVCLHVQ-KSTRDRLREGQIQSVVTYDLALDSGR 684 P + ++ C+ K VR CL K R Q++ ++ L Sbjct: 444 YPSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLD-KLKQKGAI 502 Query: 685 PHSRAVFNETKNSTRRQTQVLGLTQTCETLKLQLPNCIE--DPVSPIVLRLNFSLVGTPL 742 + +++ + + ++ T G CE L L + E D ++PI + + + L Sbjct: 503 RRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEYRLDYRTA 562 Query: 743 SAFGNLRPVLAEDAQRLFTALFPFEKNCGNDNICQDDLSITFSFMSLDCLVVGGPREFNV 802 + L+P+L + + +CG DN+C+ L ++ + +G + Sbjct: 563 ADTTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVD-SDQKKIYIGDDNPLTL 621 Query: 803 TVTVRNDGEDSYRTQVTFFFPLDLSYRKVSTLQNQRSQRSWRLACESASSTEVSGALKST 862 V +N GE +Y ++ PL + + ++N + RL+C A TE + Sbjct: 622 IVKAQNQGEGAYEAELIVSIPLQADF--IGVVRNNEALA--RLSC--AFKTE--NQTRQV 673 Query: 863 SCSINHPIFPENSEVTFNITFDVDSKASLGNKLLLKANVTSENNMPRTNKTEFQLELPVK 922 C + +P+ +++ + F V ++ + + + S N + + + V Sbjct: 674 VCDLGNPM-KAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPV---VSHKVD 729 Query: 923 YAVYMVVTSHGVSTK---YL---------NFTASENTSRVMQHQYQVSNLGQRSLPISLV 970 AV V GVS+ +L N E+ V+QH Y++ N G S +++ Sbjct: 730 LAVLAAVEIRGVSSPDHIFLPIPNWEHKENPETEEDVGPVVQHIYELRNNGPSSFSKAML 789 Query: 971 FLV-PVRLNQTVIW-------DRP-------------------QVTFSENLSSTCHTKER 1003 L P + N + D P Q T + + ++ Sbjct: 790 HLQWPYKYNNNTLLYILHYDIDGPMNCTSDMEINPLRIKISSLQTTEKNDTVAGQGERDH 849 Query: 1004 LPSHSDFLAELRKAPVVNCSIAVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYI-KTSHN 1062 L + D + C +A C +I C + + +K L + ++ K + N Sbjct: 850 LITKRDLALSEGDIHTLGCGVAQCLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKENQN 909 Query: 1063 H-LLIVSTAEILFNDSVFTLLP----GQGAFVRSQTETKVEPFEVPNPLPLIVGSSVGGL 1117 H + S+A + + LP V + ++P +P P+ +I+ + + GL Sbjct: 910 HSYSLKSSASFNVIEFPYKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAGL 969 Query: 1118 LLLALITAALYKLGFFKR 1135 LLLA++ +Y++GFFKR Sbjct: 970 LLLAVLVFVMYRMGFFKR 987 Score = 31.6 bits (70), Expect = 4.5 Identities = 36/137 (26%), Positives = 54/137 (39%), Gaps = 23/137 (16%) Query: 11 LTLCHGFNLDTENAMTFQ-ENARGFGQSV---VQLQGSR--VVVGAPQEIVAAN---QRG 61 L LC FNLD ++ + FG +V V SR ++VGAP+ + G Sbjct: 25 LPLCRAFNLDVDSPAEYSGPEGSYFGFAVDFFVPSASSRMFLLVGAPKANTTQPGIVEGG 84 Query: 62 SLYQCDY-STGSCEPIRLQV----------PVEAVNMSLGLSLAATTSPPQLLACGPTVH 110 + +CD+ ST C+PI P+E + + ++LAC P H Sbjct: 85 QVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLE-FKSHQWFGASVRSKQDKILACAPLYH 143 Query: 111 --QTCSENTYVKGLCFL 125 + G CFL Sbjct: 144 WRTEMKQEREPVGTCFL 160 >gi|4504747 integrin alpha 3 isoform a precursor [Homo sapiens] Length = 1051 Score = 164 bits (414), Expect = 6e-40 Identities = 210/871 (24%), Positives = 365/871 (41%), Gaps = 124/871 (14%) Query: 347 EHEMSQEGFSAAITSNGPLLSTVGSYDWAGGVFLYTSKEKSTFINMTRVDSDMNDAYLGY 406 E M Q G S T N G+Y+W G ++ KE + D + Y+GY Sbjct: 193 ETGMCQLGTSGGFTQNTVYFGAPGAYNWKGNSYMIQRKEWDLSEYSYKDPEDQGNLYIGY 252 Query: 407 AAAI---ILRNRVQSLVLGAPRYQHIGLVAMFRQNTGMWESNANV-KGTQIGAYFGASLC 462 + IL + ++V GAPR++H+G V + Q G V +G+Q+GAYFG+++ Sbjct: 253 TMQVGSFILHPKNITIVTGAPRHRHMGAVFLLSQEAGGDLRRRQVLEGSQVGAYFGSAIA 312 Query: 463 SVDVDSNGSTDLVLIGAPHYYEQTR--GGQVSVCPLPRGRA-RWQCDAVLYGEQGQPWGR 519 D++++G DL L+GAP+Y+E+ GG + V G + +L+G G Sbjct: 313 LADLNNDGWQDL-LVGAPYYFERKEEVGGAIYVFMNQAGTSFPAHPSLLLHGPSG---SA 368 Query: 520 FGAALTVLGDVNGDKLTDVAIGAPGEEDNRGAVYLFHGTSGSGISPSHSQRIAGSKLS-P 578 FG ++ +GD+N D D+A+GAP E G VY++H +S G+ Q I G KL P Sbjct: 369 FGLSVASIGDINQDGFQDIAVGAPFE--GLGKVYIYH-SSSKGLLRQPQQVIHGEKLGLP 425 Query: 579 RLQYFGQSLSGGQDLTMDGLVDLTVGA-QGHVLLLRSQPVLRV--KAIMEFNPREVARNV 635 L FG SLSG D+ + DL VG+ H++LLR++PV+ + K ++ PR + Sbjct: 426 GLATFGYSLSGQMDVDENFYPDLLVGSLSDHIVLLRARPVINIVHKTLV---PRPAVLDP 482 Query: 636 FECNDQVVKGKEAGEVRVCLHVQKSTRDRLREGQIQSVVTYDLALDSGRPHSRAVFNETK 695 C +V +C +S + I + Y L D R R F ++ Sbjct: 483 ALCT-----ATSCVQVELCFAYNQSAGNPNYRRNI--TLAYTLEADRDRRPPRLRFAGSE 535 Query: 696 NSTRRQTQVLGLTQTCETLKLQLPNCIEDPVSPIVLRLNFSL-VGTPLSAFGNLR----- 749 ++ + C+ L+L L + + D + PI++ +N+SL + P LR Sbjct: 536 SAVFHGFFSMP-EMRCQKLELLLMDNLRDKLRPIIISMNYSLPLRMPDRPRLGLRSLDAY 594 Query: 750 PVLAEDAQRLFTALFPFEKNCGNDNICQDDLSITFSFMSLDCLVVG------GPREFNVT 803 P+L + F+K CG DN C+ +L + +F+S + R+ ++ Sbjct: 595 PILNQAQALENHTEVQFQKECGPDNKCESNLQMRAAFVSEQQQKLSRLQYSRDVRKLLLS 654 Query: 804 VTVRN------DGEDSYRTQVTFFFPLDLSYRKVSTLQNQRSQRSWRLACESASSTEVSG 857 + V N GED++ +T P L V AC+ Sbjct: 655 INVTNTRTSERSGEDAHEALLTLVVPPALLLSSVRPPG----------ACQ--------- 695 Query: 858 ALKSTSCSINHPIFPENSEVTFNITFDVDSKASLGNKLLLKANVTSENNMPRTNKTEFQL 917 A ++ C + +P F N + I F+V L ++ +++ ++ + N L Sbjct: 696 ANETIFCELGNP-FKRNQRMELLIAFEVIGVTLHTRDLQVQLQLSTSSH--QDNLWPMIL 752 Query: 918 ELPVKYAVY--MVVTSHGVSTKY-------LNFTASENTSRVMQHQYQVSNLGQRSLPIS 968 L V Y + + + +H + + + E+ +++++QV +G+ + + Sbjct: 753 TLLVDYTLQTSLSMVNHRLQSFFGGTVMGESGMKTVEDVGSPLKYEFQVGPMGEGLVGLG 812 Query: 969 -----------------LVFLVPVRLNQTVIWD-RPQVTFSENLSSTCHTKERLPSHSD- 1009 L++ + ++ W RP L+ T PS Sbjct: 813 TLVLGLEWPYEVSNGKWLLYPTEITVHGNGSWPCRPPGDLINPLNLTLSDPGDRPSSPQR 872 Query: 1010 ----------------FLAELRKA---PVVNCSI--AVCQRIQCDIPFFGIQEEFNATLK 1048 LA +KA V+ C+ A C ++C IP + N T+K Sbjct: 873 RRRQLDPGGGQGPPPVTLAAAKKAKSETVLTCATGRAHCVWLECPIPDAPVVT--NVTVK 930 Query: 1049 GNLSFDWYIK--TSHNHLLIVSTAEILFNDSVFTL-LPGQGAFVRSQTETK-VEPFEVPN 1104 + +I+ + + + A + S+ T+ + + + +++ VE Sbjct: 931 ARVWNSTFIEDYRDFDRVRVNGWATLFLRTSIPTINMENKTTWFSVDIDSELVEELPAEI 990 Query: 1105 PLPLIVGSSVGGLLLLALITAALYKLGFFKR 1135 L L++ + GLLLL LI L+K GFFKR Sbjct: 991 ELWLVLVAVGAGLLLLGLIILLLWKCGFFKR 1021 >gi|6006011 integrin alpha 3 isoform b precursor [Homo sapiens] Length = 1066 Score = 161 bits (407), Expect = 4e-39 Identities = 209/871 (23%), Positives = 364/871 (41%), Gaps = 124/871 (14%) Query: 347 EHEMSQEGFSAAITSNGPLLSTVGSYDWAGGVFLYTSKEKSTFINMTRVDSDMNDAYLGY 406 E M Q G S T N G+Y+W G ++ KE + D + Y+GY Sbjct: 193 ETGMCQLGTSGGFTQNTVYFGAPGAYNWKGNSYMIQRKEWDLSEYSYKDPEDQGNLYIGY 252 Query: 407 AAAI---ILRNRVQSLVLGAPRYQHIGLVAMFRQNTGMWESNANV-KGTQIGAYFGASLC 462 + IL + ++V GAPR++H+G V + Q G V +G+Q+GAYFG+++ Sbjct: 253 TMQVGSFILHPKNITIVTGAPRHRHMGAVFLLSQEAGGDLRRRQVLEGSQVGAYFGSAIA 312 Query: 463 SVDVDSNGSTDLVLIGAPHYYEQTR--GGQVSVCPLPRGRA-RWQCDAVLYGEQGQPWGR 519 D++++G DL L+GAP+Y+E+ GG + V G + +L+G G Sbjct: 313 LADLNNDGWQDL-LVGAPYYFERKEEVGGAIYVFMNQAGTSFPAHPSLLLHGPSG---SA 368 Query: 520 FGAALTVLGDVNGDKLTDVAIGAPGEEDNRGAVYLFHGTSGSGISPSHSQRIAGSKLS-P 578 FG ++ +GD+N D D+A+GAP E G VY++H +S G+ Q I G KL P Sbjct: 369 FGLSVASIGDINQDGFQDIAVGAPFE--GLGKVYIYH-SSSKGLLRQPQQVIHGEKLGLP 425 Query: 579 RLQYFGQSLSGGQDLTMDGLVDLTVGA-QGHVLLLRSQPVLRV--KAIMEFNPREVARNV 635 L FG SLSG D+ + DL VG+ H++LLR++PV+ + K ++ PR + Sbjct: 426 GLATFGYSLSGQMDVDENFYPDLLVGSLSDHIVLLRARPVINIVHKTLV---PRPAVLDP 482 Query: 636 FECNDQVVKGKEAGEVRVCLHVQKSTRDRLREGQIQSVVTYDLALDSGRPHSRAVFNETK 695 C +V +C +S + I + Y L D R R F ++ Sbjct: 483 ALCT-----ATSCVQVELCFAYNQSAGNPNYRRNI--TLAYTLEADRDRRPPRLRFAGSE 535 Query: 696 NSTRRQTQVLGLTQTCETLKLQLPNCIEDPVSPIVLRLNFSL-VGTPLSAFGNLR----- 749 ++ + C+ L+L L + + D + PI++ +N+SL + P LR Sbjct: 536 SAVFHGFFSMP-EMRCQKLELLLMDNLRDKLRPIIISMNYSLPLRMPDRPRLGLRSLDAY 594 Query: 750 PVLAEDAQRLFTALFPFEKNCGNDNICQDDLSITFSFMSLDCLVVG------GPREFNVT 803 P+L + F+K CG DN C+ +L + +F+S + R+ ++ Sbjct: 595 PILNQAQALENHTEVQFQKECGPDNKCESNLQMRAAFVSEQQQKLSRLQYSRDVRKLLLS 654 Query: 804 VTVRN------DGEDSYRTQVTFFFPLDLSYRKVSTLQNQRSQRSWRLACESASSTEVSG 857 + V N GED++ +T P L V AC+ Sbjct: 655 INVTNTRTSERSGEDAHEALLTLVVPPALLLSSVRPPG----------ACQ--------- 695 Query: 858 ALKSTSCSINHPIFPENSEVTFNITFDVDSKASLGNKLLLKANVTSENNMPRTNKTEFQL 917 A ++ C + +P F N + I F+V L ++ +++ ++ + N L Sbjct: 696 ANETIFCELGNP-FKRNQRMELLIAFEVIGVTLHTRDLQVQLQLSTSSH--QDNLWPMIL 752 Query: 918 ELPVKYAVY--MVVTSHGVSTKY-------LNFTASENTSRVMQHQYQVSNLGQRSLPIS 968 L V Y + + + +H + + + E+ +++++QV +G+ + + Sbjct: 753 TLLVDYTLQTSLSMVNHRLQSFFGGTVMGESGMKTVEDVGSPLKYEFQVGPMGEGLVGLG 812 Query: 969 -----------------LVFLVPVRLNQTVIWD-RPQVTFSENLSSTCHTKERLPSHSD- 1009 L++ + ++ W RP L+ T PS Sbjct: 813 TLVLGLEWPYEVSNGKWLLYPTEITVHGNGSWPCRPPGDLINPLNLTLSDPGDRPSSPQR 872 Query: 1010 ----------------FLAELRKA---PVVNCSI--AVCQRIQCDIPFFGIQEEFNATLK 1048 LA +KA V+ C+ A C ++C IP + N T+K Sbjct: 873 RRRQLDPGGGQGPPPVTLAAAKKAKSETVLTCATGRAHCVWLECPIPDAPVVT--NVTVK 930 Query: 1049 GNLSFDWYIK--TSHNHLLIVSTAEILFNDSVFTL-LPGQGAFVRSQTETK-VEPFEVPN 1104 + +I+ + + + A + S+ T+ + + + +++ VE Sbjct: 931 ARVWNSTFIEDYRDFDRVRVNGWATLFLRTSIPTINMENKTTWFSVDIDSELVEELPAEI 990 Query: 1105 PLPLIVGSSVGGLLLLALITAALYKLGFFKR 1135 L L++ + GLLLL LI L+K FFKR Sbjct: 991 ELWLVLVAVGAGLLLLGLIILLLWKCDFFKR 1021 >gi|119395742 integrin alpha chain, alpha 6 isoform b precursor [Homo sapiens] Length = 1073 Score = 155 bits (393), Expect = 2e-37 Identities = 216/902 (23%), Positives = 387/902 (42%), Gaps = 156/902 (17%) Query: 352 QEGFSAAITSNGPLL--STVGSYDWAGGVFLYTSKEKSTFINM-------------TRVD 396 Q+G +A T + + G+Y+W G + ++ +TF +M T D Sbjct: 189 QQGVAATFTKDFHYIVFGAPGTYNWKG--IVRVEQKNNTFFDMNIFEDGPYEVGGETEHD 246 Query: 397 SDM----NDAYLGYAA----AIILRNRVQSLVLGAPRYQHIGLVAMFRQNTGMWESNANV 448 + ++YLG++ I+ ++ + + V GAPR H G V + +++ +A++ Sbjct: 247 ESLVPVPANSYLGFSLDSGKGIVSKDEI-TFVSGAPRANHSGAVVLLKRDM----KSAHL 301 Query: 449 ------KGTQIGAYFGASLCSVDVDSNGSTDLVLIGAPHYYEQTR--GGQVSVCPLPRGR 500 G + + FG + VD++ +G D+V IGAP Y+++ GG V V +GR Sbjct: 302 LPEHIFDGEGLASSFGYDVAVVDLNKDGWQDIV-IGAPQYFDRDGEVGGAVYVYMNQQGR 360 Query: 501 ARWQCDAVLYGEQGQPWGRFGAALTVLGDVNGDKLTDVAIGAPGEEDNRGAVYLFHGTSG 560 L G + FG A+ +GD+N D D+A+GAP D+ G V+++HG S Sbjct: 361 WNNVKPIRLNGTKDS---MFGIAVKNIGDINQDGYPDIAVGAP--YDDLGKVFIYHG-SA 414 Query: 561 SGISPSHSQRIAGSKLSPRLQYFGQSLSGGQDLTMDGLVDLTVGA-QGHVLLLRSQPVLR 619 +GI+ +Q + G +SP YFG S++G DL + D+ VG+ V + RS+PV+ Sbjct: 415 NGINTKPTQVLKG--ISP---YFGYSIAGNMDLDRNSYPDVAVGSLSDSVTIFRSRPVIN 469 Query: 620 VKAIMEFNPREVARNVFECNDQVVKGKEAGEVRVCLHVQKSTRDRLREGQIQSVVTYDLA 679 ++ + P + + + G +G +CL V+ ++ Sbjct: 470 IQKTITVTPNRI-----DLRQKTACGAPSG---ICLQVKSCFEYTANPAGYNPSISIVGT 521 Query: 680 LDSGRPHSRAVFNE-----TKNSTRRQTQVLGLTQ----TCETLKLQLPNCIEDPVSPIV 730 L++ + ++ + + S + TQ L L + C L L + I D + PI Sbjct: 522 LEAEKERRKSGLSSRVQFRNQGSEPKYTQELTLKRQKQKVCMEETLWLQDNIRDKLRPIP 581 Query: 731 LRLNFSLVGTP----LSAFGNLRPVLAEDAQRLFTALFPFEKN-CGNDNICQDDLSITFS 785 + + + +++ + P+L D + F K CG+DN+C +L + + Sbjct: 582 ITASVEIQEPSSRRRVNSLPEVLPILNSDEPKTAHIDVHFLKEGCGDDNVCNSNLKLEYK 641 Query: 786 FMSLDC----------------LVVGGPREFNVTVTVRN----------DGEDSYRTQVT 819 F + + LV+ ++ + +TV N DG+D++ ++ Sbjct: 642 FCTREGNQDKFSYLPIQKGVPELVLKDQKDIALEITVTNSPSNPRNPTKDGDDAHEAKLI 701 Query: 820 FFFPLDLSYRKVSTLQNQRSQRSWRLACESASSTEVSGALKSTSCSINHPIFPENSEVTF 879 FP L+Y S + R+ +L+C + + C + +P F NS VTF Sbjct: 702 ATFPDTLTY---SAYRELRAFPEKQLSCVANQNGS------QADCELGNP-FKRNSNVTF 751 Query: 880 -------NITFDVDSKASLGNKLLLKANVTSENNMPRTNKTEFQLELPVKYA-------V 925 +TFD L L L+ +N P T K + +EL + + V Sbjct: 752 YLVLSTTEVTFDTPD---LDINLKLETTSNQDNLAPITAKAKVVIELLLSVSGVAKPSQV 808 Query: 926 YM---VVTSHGVSTKYLNFTASENTSRVMQHQYQVSNLGQRSLPIS----------LVFL 972 Y VV + ++ + E RV+ ++NLG +L I L++L Sbjct: 809 YFGGTVVGEQAMKSEDEVGSLIEYEFRVINLGKPLTNLGTATLNIQWPKEISNGKWLLYL 868 Query: 973 VPVRLN--QTVIWDRPQVTFSENLSSTCH-------TKERLPSHSDF-LAELRKAPVVNC 1022 V V + V + + S NL+ + + T++++ + F L RK +NC Sbjct: 869 VKVESKGLEKVTCEPQKEINSLNLTESHNSRKKREITEKQIDDNRKFSLFAERKYQTLNC 928 Query: 1023 SIAV-CQRIQCDIPFFGIQEEFNATLKGNLSFDWYIK--TSHNHLLIVSTAEILFNDSVF 1079 S+ V C I+C P G+ + + L+ L +++ + N+L I+ A I + Sbjct: 929 SVNVNCVNIRC--PLRGLDSKASLILRSRLWNSTFLEEYSKLNYLDILMRAFIDVTAAAE 986 Query: 1080 TL-LPGQGAFVRSQT-ETKVEPFEVPNPLPLIVGSSVGGLLLLALITAALYKLGFFKRQY 1137 + LP G VR +K P +I+ + + G+L+LAL+ L+K GFFKR Sbjct: 987 NIRLPNAGTQVRVTVFPSKTVAQYSGVPWWIILVAILAGILMLALLVFILWKCGFFKRNK 1046 Query: 1138 KD 1139 KD Sbjct: 1047 KD 1048 Score = 31.6 bits (70), Expect = 4.5 Identities = 35/139 (25%), Positives = 59/139 (42%), Gaps = 24/139 (17%) Query: 17 FNLDTEN---AMTFQENARGFGQSVV---QLQGSR---VVVGAPQE----IVAANQRGSL 63 FNLDT + + FG S+ QLQ ++VGAP+ + AN+ G L Sbjct: 24 FNLDTREDNVIRKYGDPGSLFGFSLAMHWQLQPEDKRLLLVGAPRAEALPLQRANRTGGL 83 Query: 64 YQCDYST-GSCEPIRLQVPVEAVNMS-----LGLSLAATTSPPQLLACGPTVHQ-----T 112 Y CD + G C I + + S +G+++ + +++ C + T Sbjct: 84 YSCDITARGPCTRIEFDNDADPTSESKEDQWMGVTVQSQGPGGKVVTCAHRYEKRQHVNT 143 Query: 113 CSENTYVKGLCFLFGSNLR 131 E+ + G C++ NLR Sbjct: 144 KQESRDIFGRCYVLSQNLR 162 >gi|119395740 integrin alpha chain, alpha 6 isoform a precursor [Homo sapiens] Length = 1091 Score = 153 bits (386), Expect = 1e-36 Identities = 217/902 (24%), Positives = 387/902 (42%), Gaps = 156/902 (17%) Query: 352 QEGFSAAITSNGPLL--STVGSYDWAGGVFLYTSKEKSTFINM-------------TRVD 396 Q+G +A T + + G+Y+W G + ++ +TF +M T D Sbjct: 189 QQGVAATFTKDFHYIVFGAPGTYNWKG--IVRVEQKNNTFFDMNIFEDGPYEVGGETEHD 246 Query: 397 SDM----NDAYLGYAA----AIILRNRVQSLVLGAPRYQHIGLVAMFRQNTGMWESNANV 448 + ++YLG++ I+ ++ + + V GAPR H G V + +++ +A++ Sbjct: 247 ESLVPVPANSYLGFSLDSGKGIVSKDEI-TFVSGAPRANHSGAVVLLKRDM----KSAHL 301 Query: 449 ------KGTQIGAYFGASLCSVDVDSNGSTDLVLIGAPHYYEQTR--GGQVSVCPLPRGR 500 G + + FG + VD++ +G D+V IGAP Y+++ GG V V +GR Sbjct: 302 LPEHIFDGEGLASSFGYDVAVVDLNKDGWQDIV-IGAPQYFDRDGEVGGAVYVYMNQQGR 360 Query: 501 ARWQCDAVLYGEQGQPWGRFGAALTVLGDVNGDKLTDVAIGAPGEEDNRGAVYLFHGTSG 560 L G + FG A+ +GD+N D D+A+GAP D+ G V+++HG S Sbjct: 361 WNNVKPIRLNGTKDS---MFGIAVKNIGDINQDGYPDIAVGAP--YDDLGKVFIYHG-SA 414 Query: 561 SGISPSHSQRIAGSKLSPRLQYFGQSLSGGQDLTMDGLVDLTVGA-QGHVLLLRSQPVLR 619 +GI+ +Q + G +SP YFG S++G DL + D+ VG+ V + RS+PV+ Sbjct: 415 NGINTKPTQVLKG--ISP---YFGYSIAGNMDLDRNSYPDVAVGSLSDSVTIFRSRPVIN 469 Query: 620 VKAIMEFNPREVARNVFECNDQVVKGKEAGEVRVCLHVQKSTRDRLREGQIQSVVTYDLA 679 ++ + P N + + G +G +CL V+ ++ Sbjct: 470 IQKTITVTP-----NRIDLRQKTACGAPSG---ICLQVKSCFEYTANPAGYNPSISIVGT 521 Query: 680 LDSGRPH-----SRAVFNETKNSTRRQTQVLGL----TQTCETLKLQLPNCIEDPVSPIV 730 L++ + S V + S + TQ L L + C L L + I D + PI Sbjct: 522 LEAEKERRKSGLSSRVQFRNQGSEPKYTQELTLKRQKQKVCMEETLWLQDNIRDKLRPIP 581 Query: 731 LRLNFSLVGTP----LSAFGNLRPVLAEDAQRLFTALFPF-EKNCGNDNICQDDLSITFS 785 + + + +++ + P+L D + F ++ CG+DN+C +L + + Sbjct: 582 ITASVEIQEPSSRRRVNSLPEVLPILNSDEPKTAHIDVHFLKEGCGDDNVCNSNLKLEYK 641 Query: 786 FMSLDC----------------LVVGGPREFNVTVTVRN----------DGEDSYRTQVT 819 F + + LV+ ++ + +TV N DG+D++ ++ Sbjct: 642 FCTREGNQDKFSYLPIQKGVPELVLKDQKDIALEITVTNSPSNPRNPTKDGDDAHEAKLI 701 Query: 820 FFFPLDLSYRKVSTLQNQRSQRSWRLACESASSTEVSGALKSTSCSINHPIFPENSEVTF 879 FP L+Y S + R+ +L+C + + C + +P F NS VTF Sbjct: 702 ATFPDTLTY---SAYRELRAFPEKQLSCVANQNG------SQADCELGNP-FKRNSNVTF 751 Query: 880 -------NITFDVDSKASLGNKLLLKANVTSENNMPRTNKTEFQLELPVKYA-------V 925 +TFD L L L+ +N P T K + +EL + + V Sbjct: 752 YLVLSTTEVTFDT---PDLDINLKLETTSNQDNLAPITAKAKVVIELLLSVSGVAKPSQV 808 Query: 926 YM---VVTSHGVSTKYLNFTASENTSRVMQHQYQVSNLGQRSLPIS----------LVFL 972 Y VV + ++ + E RV+ ++NLG +L I L++L Sbjct: 809 YFGGTVVGEQAMKSEDEVGSLIEYEFRVINLGKPLTNLGTATLNIQWPKEISNGKWLLYL 868 Query: 973 VPVRLN--QTVIWDRPQVTFSENLSSTCH-------TKERLPSHSDF-LAELRKAPVVNC 1022 V V + V + + S NL+ + + T++++ + F L RK +NC Sbjct: 869 VKVESKGLEKVTCEPQKEINSLNLTESHNSRKKREITEKQIDDNRKFSLFAERKYQTLNC 928 Query: 1023 SIAV-CQRIQCDIPFFGIQEEFNATLKGNLSFDWYIK--TSHNHLLIVSTAEILFNDSVF 1079 S+ V C I+C P G+ + + L+ L +++ + N+L I+ A I + Sbjct: 929 SVNVNCVNIRC--PLRGLDSKASLILRSRLWNSTFLEEYSKLNYLDILMRAFIDVTAAAE 986 Query: 1080 TL-LPGQGAFVR-SQTETKVEPFEVPNPLPLIVGSSVGGLLLLALITAALYKLGFFKRQY 1137 + LP G VR + +K P +I+ + + G+L+LAL+ L+K GFFKR Sbjct: 987 NIRLPNAGTQVRVTVFPSKTVAQYSGVPWWIILVAILAGILMLALLVFILWKCGFFKRSR 1046 Query: 1138 KD 1139 D Sbjct: 1047 YD 1048 Score = 31.6 bits (70), Expect = 4.5 Identities = 35/139 (25%), Positives = 59/139 (42%), Gaps = 24/139 (17%) Query: 17 FNLDTEN---AMTFQENARGFGQSVV---QLQGSR---VVVGAPQE----IVAANQRGSL 63 FNLDT + + FG S+ QLQ ++VGAP+ + AN+ G L Sbjct: 24 FNLDTREDNVIRKYGDPGSLFGFSLAMHWQLQPEDKRLLLVGAPRAEALPLQRANRTGGL 83 Query: 64 YQCDYST-GSCEPIRLQVPVEAVNMS-----LGLSLAATTSPPQLLACGPTVHQ-----T 112 Y CD + G C I + + S +G+++ + +++ C + T Sbjct: 84 YSCDITARGPCTRIEFDNDADPTSESKEDQWMGVTVQSQGPGGKVVTCAHRYEKRQHVNT 143 Query: 113 CSENTYVKGLCFLFGSNLR 131 E+ + G C++ NLR Sbjct: 144 KQESRDIFGRCYVLSQNLR 162 >gi|49170034 integrin, alpha 8 [Homo sapiens] Length = 1063 Score = 152 bits (384), Expect = 2e-36 Identities = 204/868 (23%), Positives = 363/868 (41%), Gaps = 111/868 (12%) Query: 352 QEGFSAAITSNGPLL-STVGSYDWAGGVFL---------YTSKE---KSTFINMTRV-DS 397 Q GFS NG L+ GS+ W G V Y+ K+ K T V + Sbjct: 201 QAGFSLDFYKNGDLIVGGPGSFYWQGQVITASVADIIANYSFKDILRKLAGEKQTEVAPA 260 Query: 398 DMNDAYLGY--AAAIILRNRVQSLVLGAPR-YQHIGLVAMFRQNTGMWESNANVKGTQIG 454 +D+YLGY AA + Q LV G PR Q+ G V++ N+ N G Q+ Sbjct: 261 SYDDSYLGYSVAAGEFTGDSQQELVAGIPRGAQNFGYVSII--NSTDMTFIQNFTGEQMA 318 Query: 455 AYFGASLCSVDVDSNGSTDLVLIGAPHYYEQT------RGGQVSVCPLPRGRARWQCDAV 508 +YFG ++ DV+S+G D VL+GAP + E+ GQ+ + L ++ + Sbjct: 319 SYFGYTVVVSDVNSDGLDD-VLVGAPLFMEREFESNPREVGQIYLY-LQVSSLLFRDPQI 376 Query: 509 LYGEQGQPWGRFGAALTVLGDVNGDKLTDVAIGAP-GEEDNRGAVYLFHGTSGSGISPSH 567 L G + +GRFG+A+ LGD+N D D+AIG P +D RG V +++G G++ Sbjct: 377 LTGTE--TFGRFGSAMAHLGDLNQDGYNDIAIGVPFAGKDQRGKVLIYNGNK-DGLNTKP 433 Query: 568 SQRIAGSKLSPRL-QYFGQSLSGGQDLTMDGLVDLTVGA--QGHVLLLRSQPVLRVKAIM 624 SQ + G S + FG +L G D+ + DL VGA G V + R++PV+ V A + Sbjct: 434 SQVLQGVWASHAVPSGFGFTLRGDSDIDKNDYPDLIVGAFGTGKVAVYRARPVVTVDAQL 493 Query: 625 EFNPREVARNVFECN-DQVVKGKEAGEVRVCLHVQ----KSTRDRLREGQIQSV-----V 674 +P + C + +RVC V +T + E Q+ S+ + Sbjct: 494 LLHPMIINLENKTCQVPDSMTSAACFSLRVCASVTGQSIANTIVLMAEVQLDSLKQKGAI 553 Query: 675 TYDLALDSGRPHS-RAVFNETKNSTRRQTQVLGLTQTCETLKLQLPNCIEDPVSPIVLRL 733 L LD+ + H + + + S + Q ++ L E D +SPI + L Sbjct: 554 KRTLFLDNHQAHRVFPLVIKRQKSHQCQDFIVYLRDETE---------FRDKLSPINISL 604 Query: 734 NFSLVGTPLSAFGNLRPVLAEDAQRLFTALFPFEKNCGNDNICQDDLSITFSFMSLDCLV 793 N+SL + ++P+L + + + +CG DN+C DL ++ + ++ Sbjct: 605 NYSLDESTFKEGLEVKPILNYYRENIVSEQAHILVDCGEDNLCVPDLKLS-ARPDKHQVI 663 Query: 794 VGGPREFNVTVTVRNDGEDSYRTQVTFFFPLDLSYRKVSTLQNQRSQRSWR-LACESASS 852 +G + + RN+GE +Y ++ P + Y + +R+ + +R L+CE Sbjct: 664 IGDENHLMLIINARNEGEGAYEAELFVMIPEEADYVGI-----ERNNKGFRPLSCE---- 714 Query: 853 TEVSGALKSTSCSINHPIFPENSEVTFNITFDVDSKASLGNKLLLKANVTSEN-NMPRTN 911 ++ + C + +P+ + + + F V + + S N + P +N Sbjct: 715 YKMENVTRMVVCDLGNPMV-SGTNYSLGLRFAVPRLEKTNMSINFDLQIRSSNKDNPDSN 773 Query: 912 KTEFQLELPVKYAVYMVVTSH--GVSTKYLNFTASENTSR------VMQHQYQVSNLGQR 963 Q+ + V + SH + N+ E + +++H Y++ N+G Sbjct: 774 FVSLQINITAVAQVEIRGVSHPPQIVLPIHNWEPEEEPHKEEEVGPLVEHIYELHNIGPS 833 Query: 964 SLPISLV-----------FLVPVRLNQTV--IWDRPQVTFSENLSSTCHTKERLPSHSDF 1010 ++ +++ FL+ + QT+ + +P + + E P S F Sbjct: 834 TISDTILEVGWPFSARDEFLLYIFHIQTLGPLQCQPNPNINPQDIKPAASPEDTPELSAF 893 Query: 1011 LAE------LRK-------------APVVNCSIAVCQRIQCDIPFFGIQEEFNATLKGNL 1051 L +RK A ++NC+ C +I C + E ++ L Sbjct: 894 LRNSTIPHLVRKRDVHVVEFHRQSPAKILNCTNIECLQISCAVGRLEGGESAVLKVRSRL 953 Query: 1052 SFDWYIKTSHNHLLIVSTAEILFNDSVFT----LLPGQGAFVRSQTETKVEPFEVPNPLP 1107 +++ ++ + S +T LP +++ PL Sbjct: 954 WAHTFLQRKNDPYALASLVSFEVKKMPYTDQPAKLPEGSIAIKTSVIWATPNVSFSIPLW 1013 Query: 1108 LIVGSSVGGLLLLALITAALYKLGFFKR 1135 +I+ + + GLL+LA++T AL+K GFF R Sbjct: 1014 VIILAILLGLLVLAILTLALWKCGFFDR 1041 >gi|88758615 integrin alpha 2b preproprotein [Homo sapiens] Length = 1039 Score = 145 bits (366), Expect = 2e-34 Identities = 212/890 (23%), Positives = 351/890 (39%), Gaps = 154/890 (17%) Query: 345 SFEHEMSQEGFSAAITSNGPL-LSTVGSYDWAG----------------GVFLYTSKEKS 387 S++ + GFS+ +T G L L G Y + G G+ L+ +S Sbjct: 192 SWDKRYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVADIFSSYRPGILLWHVSSQS 251 Query: 388 TFINMTRVDSDMNDAYLGYAAAIILRN---RVQSLVLGAPRYQH-IGLVAMFRQNTGMWE 443 ++ + + D Y GY+ A+ + V+GAP + +G V + ++ Sbjct: 252 --LSFDSSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEIL---DSYYQ 306 Query: 444 SNANVKGTQIGAYFGASLCSVDVDSNGSTDLVLIGAPHYYEQTRG------GQVSVCPLP 497 ++G Q+ +YFG S+ DV+ +G DL L+GAP Y E G+V + P Sbjct: 307 RLHRLRGEQMASYFGHSVAVTDVNGDGRHDL-LVGAPLYMESRADRKLAEVGRVYLFLQP 365 Query: 498 RGRARWQCDAVLYGEQGQPWGRFGAALTVLGDVNGDKLTDVAIGAP-GEEDNRGAVYLFH 556 RG ++L Q +GRFG+A+ LGD++ D D+A+ AP G RG V +F Sbjct: 366 RGPHALGAPSLLLTGT-QLYGRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQVLVFL 424 Query: 557 GTSGSGISPSHSQRIAGSKLSPRLQYFGQSLSGGQDLTMDGLVDLTVGAQG--HVLLLRS 614 G S G+ SQ + P FG SL G D+ +G DL VGA G V + R+ Sbjct: 425 GQS-EGLRSRPSQVLDSP--FPTGSAFGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYRA 481 Query: 615 QPVLRVKAIMEFNPREVARNVFECNDQVVKGKEAGEVRV---CLHVQKSTRDRLREGQIQ 671 QPV++ V V + + VK + + C ++Q + Sbjct: 482 QPVVKAS---------VQLLVQDSLNPAVKSCVLPQTKTPVSCFNIQMCVGATGHNIPQK 532 Query: 672 SVVTYDLALDSGRPHSRAVFNETKNSTRRQTQVLGLTQTCETLKLQL-----PNC----- 721 + +L LD +P R+ +LG Q TL L L P C Sbjct: 533 LSLNAELQLDRQKPRQG-----------RRVLLLGSQQAGTTLNLDLGGKHSPICHTTMA 581 Query: 722 -------IEDPVSPIVLRLNFSLVGTPLSAFGNLRPVLAEDAQRLFTALFPFEKNCGNDN 774 D +SPIVL LN SL T + P + +CG D+ Sbjct: 582 FLRDEADFRDKLSPIVLSLNVSLPPTE----AGMAPAVVLHGDTHVQEQTRIVLDCGEDD 637 Query: 775 ICQDDLSITFSFMSLDCLVVGGPREFNVTVTVRNDGEDSYRTQVTFFFPLDLSY-RKVST 833 +C L +T S L+VG + + N+GE +Y ++ P Y R +S Sbjct: 638 VCVPQLQLTASVTGSP-LLVGADNVLELQMDAANEGEGAYEAELAVHLPQGAHYMRALSN 696 Query: 834 LQNQRSQRSWRLACESASSTEVSGALKSTSCSINHPIFPENSEVTFNITFDVDSKASLGN 893 ++ RL C E L C + +P+ +N+++ + V + G Sbjct: 697 VEGFE-----RLICNQKKENETRVVL----CELGNPM-KKNAQIGIAMLVSVGNLEEAGE 746 Query: 894 KLLLKANVTSENNMPRTNKTEFQLELPVKYAVYMVVTSHGVSTKYLNFTASENTSR---- 949 + + + S+N+ +K L++PV+ + + + + A+E R Sbjct: 747 SVSFQLQIRSKNSQNPNSKIVL-LDVPVRAEAQVELRGNSFPASLV--VAAEEGEREQNS 803 Query: 950 ------VMQHQYQVSNLGQ--------------RSLPISLVFLVPVRLN----------- 978 ++H Y++ N G +S P L++++ ++ Sbjct: 804 LDSWGPKVEHTYELHNNGPGTVNGLHLSIHLPGQSQPSDLLYILDIQPQGGLQCFPQPPV 863 Query: 979 --QTVIWDRPQVTFSENLSSTCHTKER----LPSHSDFLAELRKAPVVNCSIAVCQRIQC 1032 V W P + + H ++R LP + + L+ +V+C A C +QC Sbjct: 864 NPLKVDWGLP-IPSPSPIHPAHHKRDRRQIFLP-EPEQPSRLQDPVLVSCDSAPCTVVQC 921 Query: 1033 DIPFFGIQEEFNATLKGNLSFDWYIKTSHNHL-LIVSTAEILFNDSVFTL------LPGQ 1085 D+ + T+ L+F W L V + FN S LP Sbjct: 922 DLQEMARGQRAMVTV---LAFLWLPSLYQRPLDQFVLQSHAWFNVSSLPYAVPPLSLPRG 978 Query: 1086 GAFVRSQTETKVEPFEVPNPLPLIVGSSVGGLLLLALITAALYKLGFFKR 1135 A V +Q +E E P+ ++ +GGLLLL ++ A++K+GFFKR Sbjct: 979 EAQVWTQLLRALE--ERAIPIWWVLVGVLGGLLLLTILVLAMWKVGFFKR 1026 >gi|222418611 integrin alpha 7 isoform 2 precursor [Homo sapiens] Length = 1137 Score = 137 bits (345), Expect = 6e-32 Identities = 206/901 (22%), Positives = 359/901 (39%), Gaps = 148/901 (16%) Query: 352 QEGFSAAIT--SNGPLLSTVGSYDWAGGVFLYT--SKEKSTFINMTRVDSDMN------- 400 Q+G +AA + S+ L G+Y+W G +F+ S + + T +D Sbjct: 198 QQGTAAAFSPDSHYLLFGAPGTYNWKGLLFVTNIDSSDPDQLVYKTLDPADRLPGPAGDL 257 Query: 401 --DAYLGYAAAI---ILRNRVQSLVLGAPRYQHIGLVAMFRQNTGM-WESNANVKGTQIG 454 ++YLG++ ++R S V GAPR H G V + R+++ + G ++ Sbjct: 258 ALNSYLGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKDSASRLVPEVMLSGERLT 317 Query: 455 AYFGASLCSVDVDSNGSTDLVLIGAPHYYEQTR--GGQVSVCPLPRGRARWQCDAVLYGE 512 + FG SL D++S+G DL+ +GAP+++E+ GG V V L +G W + L Sbjct: 318 SGFGYSLAVADLNSDGWPDLI-VGAPYFFERQEELGGAVYVY-LNQG-GHWAGISPLR-L 373 Query: 513 QGQPWGRFGAALTVLGDVNGDKLTDVAIGAPGEEDNRGAVYLFHGTSGSGISPSHSQRIA 572 G P FG +L VLGD+N D D+A+GAP + D G V+++HG+S G+ SQ + Sbjct: 374 CGSPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGD--GKVFIYHGSS-LGVVAKPSQVLE 430 Query: 573 GSKLSPRLQYFGQSLSGGQDLTMDGLVDLTVGAQGH-VLLLRSQPVLRVKAIMEFNPREV 631 G + ++ FG SLSG D+ + DL VG+ +L R++P+L V + PR + Sbjct: 431 GEAVG--IKSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHEVSIAPRSI 488 Query: 632 ARNVFECNDQVVKGKEAGEVRVCLHVQKSTRDRLREGQIQSVVTYDLALDSG-----RPH 686 C AG VC+ ++ V D LD+ R Sbjct: 489 DLEQPNC---------AGGHSVCVDLRVCFSYIAVPSSYSPTVALDYVLDADTDRRLRGQ 539 Query: 687 SRAVFNETKNSTRRQTQVLGLT-------QTCETLKLQLPNCIEDPVSPIVLRLNFSLV- 738 V ++N + Q G + C QL ++D + IV+ L++SL Sbjct: 540 VPRVTFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVTLSYSLQT 599 Query: 739 -----GTPLSAFGNLRPVL-AEDAQRLFTALFPFEKNCGNDNICQDDLSIT--------- 783 P + P+L A + ++ CG D ICQ +L + Sbjct: 600 PRLRRQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRVS 659 Query: 784 ---FSFMSLD------CLVVGGPREFNVTVTVRN----------DGEDSYRTQVTFFFPL 824 F + +D + G + + V N DG+D++ Q+ P Sbjct: 660 DTEFQPLPMDVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLPD 719 Query: 825 DLSYRKVSTLQNQRSQRSWRLACESASSTEVSGALKSTSCSINHPIFPENSEVTFNITFD 884 L Y V L +++ L+ E+AS E C + +P+ ++VTF + Sbjct: 720 SLHYSGVRAL--DPAEKPLCLSNENASHVE---------CELGNPM-KRGAQVTFYLILS 767 Query: 885 VDSKASLGNKL---LLKANVTSENNMPRTNKTEFQLELPVK---YAVYMVVTSHGVSTKY 938 + +L LL A ++ + P + + +ELP+ A+ + GV Sbjct: 768 TSGISIETTELEVELLLATISEQELHPVSARARVFIELPLSIAGMAIPQQLFFSGVVRGE 827 Query: 939 LNFTASENTSRVMQHQYQVSNLGQRSLPISLVF---------------LVPVRL------ 977 + + ++++ VSN GQ + F L P+++ Sbjct: 828 RAMQSERDVGSKVKYEVTVSNQGQSLRTLGSAFLNIMWPHEIANGKWLLYPMQVELEGGQ 887 Query: 978 ---NQTVIWDRPQVTFSENLSSTCHTKERLPSHSD---------------FLAELRKAPV 1019 + + RP + + S +E P AE +K Sbjct: 888 GPGQKGLCSPRPNILHLDVDSRDRRRRELEPPEQQEPGERQEPSMSWWPVSSAEKKKNIT 947 Query: 1020 VNCSIAVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYIK--TSHNHLLIVSTAEILFNDS 1077 ++C+ + P + + G L +++ ++ L ++ A I S Sbjct: 948 LDCARGTANCVVFSCPLYSFDRAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRANITVKSS 1007 Query: 1078 VFTLLPGQGAFVRSQTETKVEPFEVPN---PLPLIVGSSVGGLLLLALITAALYKLGFFK 1134 + L+ + V ++P V P +I+ + + GLL+LAL+ L+K+GFFK Sbjct: 1008 IKNLMLRDASTV-IPVMVYLDPMAVVAEGVPWWVILLAVLAGLLVLALLVLLLWKMGFFK 1066 Query: 1135 R 1135 R Sbjct: 1067 R 1067 >gi|222418615 integrin alpha 7 isoform 3 [Homo sapiens] Length = 1044 Score = 131 bits (329), Expect = 4e-30 Identities = 204/907 (22%), Positives = 356/907 (39%), Gaps = 156/907 (17%) Query: 352 QEGFSAAIT--SNGPLLSTVGSYDWAGGVFLYTSKEKSTFINMTRVDSDMNDA------- 402 Q+G +AA + S+ L G+Y+W G + + S ++ +D +A Sbjct: 101 QQGTAAAFSPDSHYLLFGAPGTYNWKGTARVELCAQGSA--DLAHLDDGPYEAGGEKEQD 158 Query: 403 ----------YLGYAAAI---ILRNRVQSLVLGAPRYQHIGLVAMFRQNTGM-WESNANV 448 Y G++ ++R S V GAPR H G V + R+++ + Sbjct: 159 PRLIPVPANSYFGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKDSASRLVPEVML 218 Query: 449 KGTQIGAYFGASLCSVDVDSNGSTDLVLIGAPHYYEQTR--GGQVSVCPLPRGRARWQCD 506 G ++ + FG SL D++S+G DL+ +GAP+++E+ GG V V L +G W Sbjct: 219 SGERLTSGFGYSLAVADLNSDGWPDLI-VGAPYFFERQEELGGAVYVY-LNQG-GHWAGI 275 Query: 507 AVLYGEQGQPWGRFGAALTVLGDVNGDKLTDVAIGAPGEEDNRGAVYLFHGTSGSGISPS 566 + L G P FG +L VLGD+N D D+A+GAP + D G V+++HG+S G+ Sbjct: 276 SPLR-LCGSPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGD--GKVFIYHGSS-LGVVAK 331 Query: 567 HSQRIAGSKLSPRLQYFGQSLSGGQDLTMDGLVDLTVGAQGH-VLLLRSQPVLRVKAIME 625 SQ + G + ++ FG SLSG D+ + DL VG+ +L R++P+L V + Sbjct: 332 PSQVLEGEAVG--IKSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHEVS 389 Query: 626 FNPREVARNVFECNDQVVKGKEAGEVRVCLHVQKSTRDRLREGQIQSVVTYDLALDSG-- 683 PR + C AG VC+ ++ V D LD+ Sbjct: 390 IAPRSIDLEQPNC---------AGGHSVCVDLRVCFSYIAVPSSYSPTVALDYVLDADTD 440 Query: 684 ---RPHSRAVFNETKNSTRRQTQVLGLT-------QTCETLKLQLPNCIEDPVSPIVLRL 733 R V ++N + Q G + C QL ++D + IV+ L Sbjct: 441 RRLRGQVPRVTFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVTL 500 Query: 734 NFSLV------GTPLSAFGNLRPVL-AEDAQRLFTALFPFEKNCGNDNICQDDLSIT--- 783 ++SL P + P+L A + ++ CG D ICQ +L + Sbjct: 501 SYSLQTPRLRRQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRAR 560 Query: 784 ---------FSFMSLD------CLVVGGPREFNVTVTVRN----------DGEDSYRTQV 818 F + +D + G + + V N DG+D++ Q+ Sbjct: 561 FCTRVSDTEFQPLPMDVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQL 620 Query: 819 TFFFPLDLSYRKVSTLQNQRSQRSWRLACESASSTEVSGALKSTSCSINHPIFPENSEVT 878 P L Y V L +++ L+ E+AS E C + +P+ ++VT Sbjct: 621 LVMLPDSLHYSGVRAL--DPAEKPLCLSNENASHVE---------CELGNPM-KRGAQVT 668 Query: 879 FNITFDVDSKASLGNKL---LLKANVTSENNMPRTNKTEFQLELPVK---YAVYMVVTSH 932 F + + +L LL A ++ + P + + +ELP+ A+ + Sbjct: 669 FYLILSTSGISIETTELEVELLLATISEQELHPVSARARVFIELPLSIAGMAIPQQLFFS 728 Query: 933 GVSTKYLNFTASENTSRVMQHQYQVSNLGQRSLPISLVF---------------LVPVRL 977 GV + + ++++ VSN GQ + F L P+++ Sbjct: 729 GVVRGERAMQSERDVGSKVKYEVTVSNQGQSLRTLGSAFLNIMWPHEIANGKWLLYPMQV 788 Query: 978 ---------NQTVIWDRPQVTFSENLSSTCHTKERLPSHSD---------------FLAE 1013 + + RP + + S +E P AE Sbjct: 789 ELEGGQGPGQKGLCSPRPNILHLDVDSRDRRRRELEPPEQQEPGERQEPSMSWWPVSSAE 848 Query: 1014 LRKAPVVNCSIAVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYIK--TSHNHLLIVSTAE 1071 +K ++C+ + P + + G L +++ ++ L ++ A Sbjct: 849 KKKNITLDCARGTANCVVFSCPLYSFDRAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRAN 908 Query: 1072 ILFNDSVFTLLPGQGAFVRSQTETKVEPFEVPN---PLPLIVGSSVGGLLLLALITAALY 1128 I S+ L+ + V ++P V P +I+ + + GLL+LAL+ L+ Sbjct: 909 ITVKSSIKNLMLRDASTV-IPVMVYLDPMAVVAEGVPWWVILLAVLAGLLVLALLVLLLW 967 Query: 1129 KLGFFKR 1135 K+GFFKR Sbjct: 968 KMGFFKR 974 >gi|222418613 integrin alpha 7 isoform 1 precursor [Homo sapiens] Length = 1141 Score = 131 bits (329), Expect = 4e-30 Identities = 204/907 (22%), Positives = 356/907 (39%), Gaps = 156/907 (17%) Query: 352 QEGFSAAIT--SNGPLLSTVGSYDWAGGVFLYTSKEKSTFINMTRVDSDMNDA------- 402 Q+G +AA + S+ L G+Y+W G + + S ++ +D +A Sbjct: 198 QQGTAAAFSPDSHYLLFGAPGTYNWKGTARVELCAQGSA--DLAHLDDGPYEAGGEKEQD 255 Query: 403 ----------YLGYAAAI---ILRNRVQSLVLGAPRYQHIGLVAMFRQNTGM-WESNANV 448 Y G++ ++R S V GAPR H G V + R+++ + Sbjct: 256 PRLIPVPANSYFGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKDSASRLVPEVML 315 Query: 449 KGTQIGAYFGASLCSVDVDSNGSTDLVLIGAPHYYEQTR--GGQVSVCPLPRGRARWQCD 506 G ++ + FG SL D++S+G DL+ +GAP+++E+ GG V V L +G W Sbjct: 316 SGERLTSGFGYSLAVADLNSDGWPDLI-VGAPYFFERQEELGGAVYVY-LNQG-GHWAGI 372 Query: 507 AVLYGEQGQPWGRFGAALTVLGDVNGDKLTDVAIGAPGEEDNRGAVYLFHGTSGSGISPS 566 + L G P FG +L VLGD+N D D+A+GAP + D G V+++HG+S G+ Sbjct: 373 SPLR-LCGSPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGD--GKVFIYHGSS-LGVVAK 428 Query: 567 HSQRIAGSKLSPRLQYFGQSLSGGQDLTMDGLVDLTVGAQGH-VLLLRSQPVLRVKAIME 625 SQ + G + ++ FG SLSG D+ + DL VG+ +L R++P+L V + Sbjct: 429 PSQVLEGEAVG--IKSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHEVS 486 Query: 626 FNPREVARNVFECNDQVVKGKEAGEVRVCLHVQKSTRDRLREGQIQSVVTYDLALDSG-- 683 PR + C AG VC+ ++ V D LD+ Sbjct: 487 IAPRSIDLEQPNC---------AGGHSVCVDLRVCFSYIAVPSSYSPTVALDYVLDADTD 537 Query: 684 ---RPHSRAVFNETKNSTRRQTQVLGLT-------QTCETLKLQLPNCIEDPVSPIVLRL 733 R V ++N + Q G + C QL ++D + IV+ L Sbjct: 538 RRLRGQVPRVTFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVTL 597 Query: 734 NFSLV------GTPLSAFGNLRPVL-AEDAQRLFTALFPFEKNCGNDNICQDDLSIT--- 783 ++SL P + P+L A + ++ CG D ICQ +L + Sbjct: 598 SYSLQTPRLRRQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRAR 657 Query: 784 ---------FSFMSLD------CLVVGGPREFNVTVTVRN----------DGEDSYRTQV 818 F + +D + G + + V N DG+D++ Q+ Sbjct: 658 FCTRVSDTEFQPLPMDVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQL 717 Query: 819 TFFFPLDLSYRKVSTLQNQRSQRSWRLACESASSTEVSGALKSTSCSINHPIFPENSEVT 878 P L Y V L +++ L+ E+AS E C + +P+ ++VT Sbjct: 718 LVMLPDSLHYSGVRAL--DPAEKPLCLSNENASHVE---------CELGNPM-KRGAQVT 765 Query: 879 FNITFDVDSKASLGNKL---LLKANVTSENNMPRTNKTEFQLELPVK---YAVYMVVTSH 932 F + + +L LL A ++ + P + + +ELP+ A+ + Sbjct: 766 FYLILSTSGISIETTELEVELLLATISEQELHPVSARARVFIELPLSIAGMAIPQQLFFS 825 Query: 933 GVSTKYLNFTASENTSRVMQHQYQVSNLGQRSLPISLVF---------------LVPVRL 977 GV + + ++++ VSN GQ + F L P+++ Sbjct: 826 GVVRGERAMQSERDVGSKVKYEVTVSNQGQSLRTLGSAFLNIMWPHEIANGKWLLYPMQV 885 Query: 978 ---------NQTVIWDRPQVTFSENLSSTCHTKERLPSHSD---------------FLAE 1013 + + RP + + S +E P AE Sbjct: 886 ELEGGQGPGQKGLCSPRPNILHLDVDSRDRRRRELEPPEQQEPGERQEPSMSWWPVSSAE 945 Query: 1014 LRKAPVVNCSIAVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYIK--TSHNHLLIVSTAE 1071 +K ++C+ + P + + G L +++ ++ L ++ A Sbjct: 946 KKKNITLDCARGTANCVVFSCPLYSFDRAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRAN 1005 Query: 1072 ILFNDSVFTLLPGQGAFVRSQTETKVEPFEVPN---PLPLIVGSSVGGLLLLALITAALY 1128 I S+ L+ + V ++P V P +I+ + + GLL+LAL+ L+ Sbjct: 1006 ITVKSSIKNLMLRDASTV-IPVMVYLDPMAVVAEGVPWWVILLAVLAGLLVLALLVLLLW 1064 Query: 1129 KLGFFKR 1135 K+GFFKR Sbjct: 1065 KMGFFKR 1071 >gi|4505111 matrilin 1, cartilage matrix protein [Homo sapiens] Length = 496 Score = 93.6 bits (231), Expect = 1e-18 Identities = 63/218 (28%), Positives = 109/218 (50%), Gaps = 19/218 (8%) Query: 149 SDIAFLIDGSGSIIPHDFRRMKEFVSTVMEQLKKSKTL--FSLMQYSEEFRIHFTFKEFQ 206 +D+ FLIDGS S+ P +F +K+F+S +++ L S L L+QYS R F F Sbjct: 274 TDLVFLIDGSKSVRPENFELVKKFISQIVDTLDVSDKLAQVGLVQYSSSVRQEFPLGRFH 333 Query: 207 NNPNPRSLVKPITQLLGRTHTATGIRKVVRELFNITNGARKNAFKILVVITDGEKFGDPL 266 + ++ V+ ++ + T T ++ ++ F +++GAR A K+ +V TDG Sbjct: 334 TKKDIKAAVRNMSYMEKGTMTGAALKYLIDNSFTVSSGARPGAQKVGIVFTDGRS----- 388 Query: 267 GYEDVIPEADRE----GVIRYVIGVGDAFRSEKSRQELNTIASKPPRDHVFQVNNFEALK 322 +D I +A ++ G + +GVG+A EL IAS+P +H F +F+ + Sbjct: 389 --QDYINDAAKKAKDLGFKMFAVGVGNAV-----EDELREIASEPVAEHYFYTADFKTIN 441 Query: 323 TIQNQLREKIFAIEGTQTGSSSSFEHEMSQEGFSAAIT 360 I +L++KI +E S + + EG A+T Sbjct: 442 QIGKKLQKKI-CVEEDPCACESLVKFQAKVEGLLQALT 478 Score = 70.5 bits (171), Expect = 9e-12 Identities = 49/192 (25%), Positives = 88/192 (45%), Gaps = 13/192 (6%) Query: 144 CPQEDSDIAFLIDGSGSIIPHDFRRMKEFVSTVMEQLK--KSKTLFSLMQYSEEFRIHFT 201 C +D+ F++D S S+ P +F ++K F+S V+E L + T ++ Y+ + F+ Sbjct: 35 CRTRPTDLVFVVDSSRSVRPVEFEKVKVFLSQVIESLDVGPNATRVGMVNYASTVKQEFS 94 Query: 202 FKEFQNNPNPRSLVKPITQLLGRTHTATGIRKVVRELFNITNGARKNA---FKILVVITD 258 + + V+ I L T T I+ + + F G R + K+++V+TD Sbjct: 95 LRAHVSKAALLQAVRRIQPLSTGTMTGLAIQFAITKAFGDAEGGRSRSPDISKVVIVVTD 154 Query: 259 GEKFGDPLGYEDVIPEADREGVIRYVIGVGDAFRSEKSRQELNTIASKPPRDHVFQVNNF 318 G +DV A GV + IGVG + L IAS+P +HV V ++ Sbjct: 155 GRPQDS---VQDVSARARASGVELFAIGVGSV-----DKATLRQIASEPQDEHVDYVESY 206 Query: 319 EALKTIQNQLRE 330 ++ + + +E Sbjct: 207 SVIEKLSRKFQE 218 >gi|55743096 collagen, type XIV, alpha 1 [Homo sapiens] Length = 1796 Score = 90.9 bits (224), Expect = 6e-18 Identities = 61/198 (30%), Positives = 97/198 (48%), Gaps = 11/198 (5%) Query: 134 PQKFPEALRGCPQEDSDIAFLIDGSGSIIPHDFRRMKEFVSTVMEQLKK---SKTLFSLM 190 P P A C +D+ F++DGS SI +F ++ F+ + + L K T +++ Sbjct: 1016 PPTIPPAKEVCKAAKADLVFMVDGSWSIGDENFNKIISFLYSTVGALNKIGTDGTQVAMV 1075 Query: 191 QYSEEFRIHFTFKEFQNNPNPRSLVKPITQLLGRTHTATGIRKVVRELFNITNGARKNAF 250 Q++++ R F ++ +K I+ G T T I+ V LF +G R+ Sbjct: 1076 QFTDDPRTEFKLNAYKTKETLLDAIKHISYKGGNTKTGKAIKYVRDTLFTAESGTRRGIP 1135 Query: 251 KILVVITDGEKFGDPLGYEDVIPEADREGVIRYVIGVGDAFRSEKSRQELNTIASKPPRD 310 K++VVITDG D + E +G + IGV DA S EL +I SKP Sbjct: 1136 KVIVVITDGRSQDD---VNKISREMQLDGYSIFAIGVADADYS-----ELVSIGSKPSAR 1187 Query: 311 HVFQVNNFEALKTIQNQL 328 HVF V++F+A K I+++L Sbjct: 1188 HVFFVDDFDAFKKIEDEL 1205 Score = 71.2 bits (173), Expect = 5e-12 Identities = 54/185 (29%), Positives = 83/185 (44%), Gaps = 16/185 (8%) Query: 149 SDIAFLIDGSGSIIPHDFRRMKEFVSTVME--QLKKSKTLFSLMQYSEEFRIHFTFKEFQ 206 +DI L+DGS SI +FR ++ F+ ++ + KT L QYS + RI + F Sbjct: 157 ADIVILVDGSWSIGRFNFRLVRHFLENLVTAFDVGSEKTRIGLAQYSGDPRIEWHLNAFS 216 Query: 207 NNPNPRSLVKPITQLLGRTHTATGIRKVVRELFNITNGARKNAFKILVVITDGEKFGDPL 266 V+ + G T T + + F G+R KI ++ITDG+ Sbjct: 217 TKDEVIEAVRNLPYKGGNTLTGLALNYIFENSFKPEAGSRTGVSKIGILITDGK------ 270 Query: 267 GYEDVIPEA---DREGVIRYVIGVGDAFRSEKSRQELNTIASKPPRDHVFQVNNFEALKT 323 +D+IP + GV + IGV +A EL IAS+P HV+ V F+ + T Sbjct: 271 SQDDIIPPSRNLRESGVELFAIGVKNA-----DVNELQEIASEPDSTHVYNVAEFDLMHT 325 Query: 324 IQNQL 328 + L Sbjct: 326 VVESL 330 >gi|62548862 matrilin 2 isoform b precursor [Homo sapiens] Length = 937 Score = 86.7 bits (213), Expect = 1e-16 Identities = 64/238 (26%), Positives = 109/238 (45%), Gaps = 18/238 (7%) Query: 102 LLACGPTVHQTCSENTYVKGLCFLFGSNLRQQPQKFPEAL--RGCPQEDSDIAFLIDGSG 159 LL G V +G G + R PQ AL C + +D+ F+ID S Sbjct: 10 LLILGQIVLLPAEARERSRGRSISRGRHARTHPQT---ALLESSCENKRADLVFIIDSSR 66 Query: 160 SIIPHDFRRMKEFVSTVME--QLKKSKTLFSLMQYSEEFRIHFTFKEFQNNPNPRSLVKP 217 S+ HD+ ++KEF+ +++ + T L+QY + F+ K F+ VK Sbjct: 67 SVNTHDYAKVKEFIVDILQFLDIGPDVTRVGLLQYGSTVKNEFSLKTFKRKSEVERAVKR 126 Query: 218 ITQLLGRTHTATGIRKVVRELFNITNGA---RKNAFKILVVITDGEKFGDPLGYEDVIPE 274 + L T T I+ + F+ GA R+N ++++++TDG +V + Sbjct: 127 MRHLSTGTMTGLAIQYALNIAFSEAEGARPLRENVPRVIMIVTDGRPQD---SVAEVAAK 183 Query: 275 ADREGVIRYVIGVGDAFRSEKSRQELNTIASKPPRDHVFQVNNFEALKTIQNQLREKI 332 A G++ + IGVG + L +I S+P DHVF V NF ++T+ + ++K+ Sbjct: 184 ARDTGILIFAIGVG-----QVDFNTLKSIGSEPHEDHVFLVANFSQIETLTSVFQKKL 236 Score = 75.1 bits (183), Expect = 4e-13 Identities = 51/194 (26%), Positives = 90/194 (46%), Gaps = 13/194 (6%) Query: 144 CPQEDSDIAFLIDGSGSIIPHDFRRMKEFVSTVMEQLKKS--KTLFSLMQYSEEFRIHFT 201 C + D+ F+IDGS S+ +F +K+FV+ +++ L S L+QYS + FT Sbjct: 649 CTEGPIDLVFVIDGSKSLGEENFEVVKQFVTGIIDSLTISPKAARVGLLQYSTQVHTEFT 708 Query: 202 FKEFQNNPNPRSLVKPITQLLGRTHTATGIRKVVRELFNITNGARKNAFKI---LVVITD 258 + F + + + V + + + T ++ + F GAR + ++ +V TD Sbjct: 709 LRNFNSAKDMKKAVAHMKYMGKGSMTGLALKHMFERSFTQGEGARPLSTRVPRAAIVFTD 768 Query: 259 GEKFGDPLGYEDVIPEADREGVIRYVIGVGDAFRSEKSRQELNTIASKPPRDHVFQVNNF 318 G D + +A G+ Y +GVG A +EL IAS+P H+F +F Sbjct: 769 GRAQDD---VSEWASKAKANGITMYAVGVGKAI-----EEELQEIASEPTNKHLFYAEDF 820 Query: 319 EALKTIQNQLREKI 332 + I +L++ I Sbjct: 821 STMDEISEKLKKGI 834 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.319 0.134 0.394 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 42,449,591 Number of Sequences: 37866 Number of extensions: 1883836 Number of successful extensions: 4391 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 57 Number of HSP's successfully gapped in prelim test: 19 Number of HSP's that attempted gapping in prelim test: 3919 Number of HSP's gapped (non-prelim): 189 length of query: 1152 length of database: 18,247,518 effective HSP length: 113 effective length of query: 1039 effective length of database: 13,968,660 effective search space: 14513437740 effective search space used: 14513437740 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.