Guide to the Human Genome
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Search of human proteins with 88501734

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|88501734 integrin alpha M isoform 2 precursor [Homo sapiens]
         (1152 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|88501734 integrin alpha M isoform 2 precursor [Homo sapiens]      2296   0.0  
gi|224831239 integrin alpha M isoform 1 precursor [Homo sapiens]     2292   0.0  
gi|34452173 integrin alpha X precursor [Homo sapiens]                1358   0.0  
gi|62548866 integrin, alpha D precursor [Homo sapiens]               1329   0.0  
gi|167466215 integrin alpha L isoform a precursor [Homo sapiens]      577   e-164
gi|167466217 integrin alpha L isoform b precursor [Homo sapiens]      473   e-133
gi|148728188 integrin, alpha E precursor [Homo sapiens]               417   e-116
gi|239751058 PREDICTED: hypothetical protein XP_002347690 [Homo ...   406   e-113
gi|31657142 integrin, alpha 1 precursor [Homo sapiens]                397   e-110
gi|52485853 integrin, alpha 11 precursor [Homo sapiens]               380   e-105
gi|38569398 integrin, alpha 10 precursor [Homo sapiens]               380   e-105
gi|116295258 integrin alpha 2 precursor [Homo sapiens]                373   e-103
gi|52485941 integrin, alpha 9 precursor [Homo sapiens]                213   1e-54
gi|67191027 integrin alpha 4 precursor [Homo sapiens]                 212   2e-54
gi|223468595 integrin alpha-V isoform 2 [Homo sapiens]                168   2e-41
gi|4504763 integrin alpha-V isoform 1 precursor [Homo sapiens]        168   2e-41
gi|56237029 integrin alpha 5 precursor [Homo sapiens]                 168   3e-41
gi|223468597 integrin alpha-V isoform 3 precursor [Homo sapiens]      164   3e-40
gi|4504747 integrin alpha 3 isoform a precursor [Homo sapiens]        164   6e-40
gi|6006011 integrin alpha 3 isoform b precursor [Homo sapiens]        161   4e-39
gi|119395742 integrin alpha chain, alpha 6 isoform b precursor [...   155   2e-37
gi|119395740 integrin alpha chain, alpha 6 isoform a precursor [...   153   1e-36
gi|49170034 integrin, alpha 8 [Homo sapiens]                          152   2e-36
gi|88758615 integrin alpha 2b preproprotein [Homo sapiens]            145   2e-34
gi|222418611 integrin alpha 7 isoform 2 precursor [Homo sapiens]      137   6e-32
gi|222418615 integrin alpha 7 isoform 3 [Homo sapiens]                131   4e-30
gi|222418613 integrin alpha 7 isoform 1 precursor [Homo sapiens]      131   4e-30
gi|4505111 matrilin 1, cartilage matrix protein [Homo sapiens]         94   1e-18
gi|55743096 collagen, type XIV, alpha 1 [Homo sapiens]                 91   6e-18
gi|62548862 matrilin 2 isoform b precursor [Homo sapiens]              87   1e-16

>gi|88501734 integrin alpha M isoform 2 precursor [Homo sapiens]
          Length = 1152

 Score = 2296 bits (5951), Expect = 0.0
 Identities = 1152/1152 (100%), Positives = 1152/1152 (100%)

Query: 1    MALRVLLLTALTLCHGFNLDTENAMTFQENARGFGQSVVQLQGSRVVVGAPQEIVAANQR 60
            MALRVLLLTALTLCHGFNLDTENAMTFQENARGFGQSVVQLQGSRVVVGAPQEIVAANQR
Sbjct: 1    MALRVLLLTALTLCHGFNLDTENAMTFQENARGFGQSVVQLQGSRVVVGAPQEIVAANQR 60

Query: 61   GSLYQCDYSTGSCEPIRLQVPVEAVNMSLGLSLAATTSPPQLLACGPTVHQTCSENTYVK 120
            GSLYQCDYSTGSCEPIRLQVPVEAVNMSLGLSLAATTSPPQLLACGPTVHQTCSENTYVK
Sbjct: 61   GSLYQCDYSTGSCEPIRLQVPVEAVNMSLGLSLAATTSPPQLLACGPTVHQTCSENTYVK 120

Query: 121  GLCFLFGSNLRQQPQKFPEALRGCPQEDSDIAFLIDGSGSIIPHDFRRMKEFVSTVMEQL 180
            GLCFLFGSNLRQQPQKFPEALRGCPQEDSDIAFLIDGSGSIIPHDFRRMKEFVSTVMEQL
Sbjct: 121  GLCFLFGSNLRQQPQKFPEALRGCPQEDSDIAFLIDGSGSIIPHDFRRMKEFVSTVMEQL 180

Query: 181  KKSKTLFSLMQYSEEFRIHFTFKEFQNNPNPRSLVKPITQLLGRTHTATGIRKVVRELFN 240
            KKSKTLFSLMQYSEEFRIHFTFKEFQNNPNPRSLVKPITQLLGRTHTATGIRKVVRELFN
Sbjct: 181  KKSKTLFSLMQYSEEFRIHFTFKEFQNNPNPRSLVKPITQLLGRTHTATGIRKVVRELFN 240

Query: 241  ITNGARKNAFKILVVITDGEKFGDPLGYEDVIPEADREGVIRYVIGVGDAFRSEKSRQEL 300
            ITNGARKNAFKILVVITDGEKFGDPLGYEDVIPEADREGVIRYVIGVGDAFRSEKSRQEL
Sbjct: 241  ITNGARKNAFKILVVITDGEKFGDPLGYEDVIPEADREGVIRYVIGVGDAFRSEKSRQEL 300

Query: 301  NTIASKPPRDHVFQVNNFEALKTIQNQLREKIFAIEGTQTGSSSSFEHEMSQEGFSAAIT 360
            NTIASKPPRDHVFQVNNFEALKTIQNQLREKIFAIEGTQTGSSSSFEHEMSQEGFSAAIT
Sbjct: 301  NTIASKPPRDHVFQVNNFEALKTIQNQLREKIFAIEGTQTGSSSSFEHEMSQEGFSAAIT 360

Query: 361  SNGPLLSTVGSYDWAGGVFLYTSKEKSTFINMTRVDSDMNDAYLGYAAAIILRNRVQSLV 420
            SNGPLLSTVGSYDWAGGVFLYTSKEKSTFINMTRVDSDMNDAYLGYAAAIILRNRVQSLV
Sbjct: 361  SNGPLLSTVGSYDWAGGVFLYTSKEKSTFINMTRVDSDMNDAYLGYAAAIILRNRVQSLV 420

Query: 421  LGAPRYQHIGLVAMFRQNTGMWESNANVKGTQIGAYFGASLCSVDVDSNGSTDLVLIGAP 480
            LGAPRYQHIGLVAMFRQNTGMWESNANVKGTQIGAYFGASLCSVDVDSNGSTDLVLIGAP
Sbjct: 421  LGAPRYQHIGLVAMFRQNTGMWESNANVKGTQIGAYFGASLCSVDVDSNGSTDLVLIGAP 480

Query: 481  HYYEQTRGGQVSVCPLPRGRARWQCDAVLYGEQGQPWGRFGAALTVLGDVNGDKLTDVAI 540
            HYYEQTRGGQVSVCPLPRGRARWQCDAVLYGEQGQPWGRFGAALTVLGDVNGDKLTDVAI
Sbjct: 481  HYYEQTRGGQVSVCPLPRGRARWQCDAVLYGEQGQPWGRFGAALTVLGDVNGDKLTDVAI 540

Query: 541  GAPGEEDNRGAVYLFHGTSGSGISPSHSQRIAGSKLSPRLQYFGQSLSGGQDLTMDGLVD 600
            GAPGEEDNRGAVYLFHGTSGSGISPSHSQRIAGSKLSPRLQYFGQSLSGGQDLTMDGLVD
Sbjct: 541  GAPGEEDNRGAVYLFHGTSGSGISPSHSQRIAGSKLSPRLQYFGQSLSGGQDLTMDGLVD 600

Query: 601  LTVGAQGHVLLLRSQPVLRVKAIMEFNPREVARNVFECNDQVVKGKEAGEVRVCLHVQKS 660
            LTVGAQGHVLLLRSQPVLRVKAIMEFNPREVARNVFECNDQVVKGKEAGEVRVCLHVQKS
Sbjct: 601  LTVGAQGHVLLLRSQPVLRVKAIMEFNPREVARNVFECNDQVVKGKEAGEVRVCLHVQKS 660

Query: 661  TRDRLREGQIQSVVTYDLALDSGRPHSRAVFNETKNSTRRQTQVLGLTQTCETLKLQLPN 720
            TRDRLREGQIQSVVTYDLALDSGRPHSRAVFNETKNSTRRQTQVLGLTQTCETLKLQLPN
Sbjct: 661  TRDRLREGQIQSVVTYDLALDSGRPHSRAVFNETKNSTRRQTQVLGLTQTCETLKLQLPN 720

Query: 721  CIEDPVSPIVLRLNFSLVGTPLSAFGNLRPVLAEDAQRLFTALFPFEKNCGNDNICQDDL 780
            CIEDPVSPIVLRLNFSLVGTPLSAFGNLRPVLAEDAQRLFTALFPFEKNCGNDNICQDDL
Sbjct: 721  CIEDPVSPIVLRLNFSLVGTPLSAFGNLRPVLAEDAQRLFTALFPFEKNCGNDNICQDDL 780

Query: 781  SITFSFMSLDCLVVGGPREFNVTVTVRNDGEDSYRTQVTFFFPLDLSYRKVSTLQNQRSQ 840
            SITFSFMSLDCLVVGGPREFNVTVTVRNDGEDSYRTQVTFFFPLDLSYRKVSTLQNQRSQ
Sbjct: 781  SITFSFMSLDCLVVGGPREFNVTVTVRNDGEDSYRTQVTFFFPLDLSYRKVSTLQNQRSQ 840

Query: 841  RSWRLACESASSTEVSGALKSTSCSINHPIFPENSEVTFNITFDVDSKASLGNKLLLKAN 900
            RSWRLACESASSTEVSGALKSTSCSINHPIFPENSEVTFNITFDVDSKASLGNKLLLKAN
Sbjct: 841  RSWRLACESASSTEVSGALKSTSCSINHPIFPENSEVTFNITFDVDSKASLGNKLLLKAN 900

Query: 901  VTSENNMPRTNKTEFQLELPVKYAVYMVVTSHGVSTKYLNFTASENTSRVMQHQYQVSNL 960
            VTSENNMPRTNKTEFQLELPVKYAVYMVVTSHGVSTKYLNFTASENTSRVMQHQYQVSNL
Sbjct: 901  VTSENNMPRTNKTEFQLELPVKYAVYMVVTSHGVSTKYLNFTASENTSRVMQHQYQVSNL 960

Query: 961  GQRSLPISLVFLVPVRLNQTVIWDRPQVTFSENLSSTCHTKERLPSHSDFLAELRKAPVV 1020
            GQRSLPISLVFLVPVRLNQTVIWDRPQVTFSENLSSTCHTKERLPSHSDFLAELRKAPVV
Sbjct: 961  GQRSLPISLVFLVPVRLNQTVIWDRPQVTFSENLSSTCHTKERLPSHSDFLAELRKAPVV 1020

Query: 1021 NCSIAVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYIKTSHNHLLIVSTAEILFNDSVFT 1080
            NCSIAVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYIKTSHNHLLIVSTAEILFNDSVFT
Sbjct: 1021 NCSIAVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYIKTSHNHLLIVSTAEILFNDSVFT 1080

Query: 1081 LLPGQGAFVRSQTETKVEPFEVPNPLPLIVGSSVGGLLLLALITAALYKLGFFKRQYKDM 1140
            LLPGQGAFVRSQTETKVEPFEVPNPLPLIVGSSVGGLLLLALITAALYKLGFFKRQYKDM
Sbjct: 1081 LLPGQGAFVRSQTETKVEPFEVPNPLPLIVGSSVGGLLLLALITAALYKLGFFKRQYKDM 1140

Query: 1141 MSEGGPPGAEPQ 1152
            MSEGGPPGAEPQ
Sbjct: 1141 MSEGGPPGAEPQ 1152


>gi|224831239 integrin alpha M isoform 1 precursor [Homo sapiens]
          Length = 1153

 Score = 2292 bits (5939), Expect = 0.0
 Identities = 1152/1153 (99%), Positives = 1152/1153 (99%), Gaps = 1/1153 (0%)

Query: 1    MALRVLLLTALTLCHGFNLDTENAMTFQENARGFGQSVVQLQGSRVVVGAPQEIVAANQR 60
            MALRVLLLTALTLCHGFNLDTENAMTFQENARGFGQSVVQLQGSRVVVGAPQEIVAANQR
Sbjct: 1    MALRVLLLTALTLCHGFNLDTENAMTFQENARGFGQSVVQLQGSRVVVGAPQEIVAANQR 60

Query: 61   GSLYQCDYSTGSCEPIRLQVPVEAVNMSLGLSLAATTSPPQLLACGPTVHQTCSENTYVK 120
            GSLYQCDYSTGSCEPIRLQVPVEAVNMSLGLSLAATTSPPQLLACGPTVHQTCSENTYVK
Sbjct: 61   GSLYQCDYSTGSCEPIRLQVPVEAVNMSLGLSLAATTSPPQLLACGPTVHQTCSENTYVK 120

Query: 121  GLCFLFGSNLRQQPQKFPEALRGCPQEDSDIAFLIDGSGSIIPHDFRRMKEFVSTVMEQL 180
            GLCFLFGSNLRQQPQKFPEALRGCPQEDSDIAFLIDGSGSIIPHDFRRMKEFVSTVMEQL
Sbjct: 121  GLCFLFGSNLRQQPQKFPEALRGCPQEDSDIAFLIDGSGSIIPHDFRRMKEFVSTVMEQL 180

Query: 181  KKSKTLFSLMQYSEEFRIHFTFKEFQNNPNPRSLVKPITQLLGRTHTATGIRKVVRELFN 240
            KKSKTLFSLMQYSEEFRIHFTFKEFQNNPNPRSLVKPITQLLGRTHTATGIRKVVRELFN
Sbjct: 181  KKSKTLFSLMQYSEEFRIHFTFKEFQNNPNPRSLVKPITQLLGRTHTATGIRKVVRELFN 240

Query: 241  ITNGARKNAFKILVVITDGEKFGDPLGYEDVIPEADREGVIRYVIGVGDAFRSEKSRQEL 300
            ITNGARKNAFKILVVITDGEKFGDPLGYEDVIPEADREGVIRYVIGVGDAFRSEKSRQEL
Sbjct: 241  ITNGARKNAFKILVVITDGEKFGDPLGYEDVIPEADREGVIRYVIGVGDAFRSEKSRQEL 300

Query: 301  NTIASKPPRDHVFQVNNFEALKTIQNQLREKIFAIEGTQTGSSSSFEHEMSQEGFSAAIT 360
            NTIASKPPRDHVFQVNNFEALKTIQNQLREKIFAIEGTQTGSSSSFEHEMSQEGFSAAIT
Sbjct: 301  NTIASKPPRDHVFQVNNFEALKTIQNQLREKIFAIEGTQTGSSSSFEHEMSQEGFSAAIT 360

Query: 361  SNGPLLSTVGSYDWAGGVFLYTSKEKSTFINMTRVDSDMNDAYLGYAAAIILRNRVQSLV 420
            SNGPLLSTVGSYDWAGGVFLYTSKEKSTFINMTRVDSDMNDAYLGYAAAIILRNRVQSLV
Sbjct: 361  SNGPLLSTVGSYDWAGGVFLYTSKEKSTFINMTRVDSDMNDAYLGYAAAIILRNRVQSLV 420

Query: 421  LGAPRYQHIGLVAMFRQNTGMWESNANVKGTQIGAYFGASLCSVDVDSNGSTDLVLIGAP 480
            LGAPRYQHIGLVAMFRQNTGMWESNANVKGTQIGAYFGASLCSVDVDSNGSTDLVLIGAP
Sbjct: 421  LGAPRYQHIGLVAMFRQNTGMWESNANVKGTQIGAYFGASLCSVDVDSNGSTDLVLIGAP 480

Query: 481  HYYEQTRGGQVSVCPLPRG-RARWQCDAVLYGEQGQPWGRFGAALTVLGDVNGDKLTDVA 539
            HYYEQTRGGQVSVCPLPRG RARWQCDAVLYGEQGQPWGRFGAALTVLGDVNGDKLTDVA
Sbjct: 481  HYYEQTRGGQVSVCPLPRGQRARWQCDAVLYGEQGQPWGRFGAALTVLGDVNGDKLTDVA 540

Query: 540  IGAPGEEDNRGAVYLFHGTSGSGISPSHSQRIAGSKLSPRLQYFGQSLSGGQDLTMDGLV 599
            IGAPGEEDNRGAVYLFHGTSGSGISPSHSQRIAGSKLSPRLQYFGQSLSGGQDLTMDGLV
Sbjct: 541  IGAPGEEDNRGAVYLFHGTSGSGISPSHSQRIAGSKLSPRLQYFGQSLSGGQDLTMDGLV 600

Query: 600  DLTVGAQGHVLLLRSQPVLRVKAIMEFNPREVARNVFECNDQVVKGKEAGEVRVCLHVQK 659
            DLTVGAQGHVLLLRSQPVLRVKAIMEFNPREVARNVFECNDQVVKGKEAGEVRVCLHVQK
Sbjct: 601  DLTVGAQGHVLLLRSQPVLRVKAIMEFNPREVARNVFECNDQVVKGKEAGEVRVCLHVQK 660

Query: 660  STRDRLREGQIQSVVTYDLALDSGRPHSRAVFNETKNSTRRQTQVLGLTQTCETLKLQLP 719
            STRDRLREGQIQSVVTYDLALDSGRPHSRAVFNETKNSTRRQTQVLGLTQTCETLKLQLP
Sbjct: 661  STRDRLREGQIQSVVTYDLALDSGRPHSRAVFNETKNSTRRQTQVLGLTQTCETLKLQLP 720

Query: 720  NCIEDPVSPIVLRLNFSLVGTPLSAFGNLRPVLAEDAQRLFTALFPFEKNCGNDNICQDD 779
            NCIEDPVSPIVLRLNFSLVGTPLSAFGNLRPVLAEDAQRLFTALFPFEKNCGNDNICQDD
Sbjct: 721  NCIEDPVSPIVLRLNFSLVGTPLSAFGNLRPVLAEDAQRLFTALFPFEKNCGNDNICQDD 780

Query: 780  LSITFSFMSLDCLVVGGPREFNVTVTVRNDGEDSYRTQVTFFFPLDLSYRKVSTLQNQRS 839
            LSITFSFMSLDCLVVGGPREFNVTVTVRNDGEDSYRTQVTFFFPLDLSYRKVSTLQNQRS
Sbjct: 781  LSITFSFMSLDCLVVGGPREFNVTVTVRNDGEDSYRTQVTFFFPLDLSYRKVSTLQNQRS 840

Query: 840  QRSWRLACESASSTEVSGALKSTSCSINHPIFPENSEVTFNITFDVDSKASLGNKLLLKA 899
            QRSWRLACESASSTEVSGALKSTSCSINHPIFPENSEVTFNITFDVDSKASLGNKLLLKA
Sbjct: 841  QRSWRLACESASSTEVSGALKSTSCSINHPIFPENSEVTFNITFDVDSKASLGNKLLLKA 900

Query: 900  NVTSENNMPRTNKTEFQLELPVKYAVYMVVTSHGVSTKYLNFTASENTSRVMQHQYQVSN 959
            NVTSENNMPRTNKTEFQLELPVKYAVYMVVTSHGVSTKYLNFTASENTSRVMQHQYQVSN
Sbjct: 901  NVTSENNMPRTNKTEFQLELPVKYAVYMVVTSHGVSTKYLNFTASENTSRVMQHQYQVSN 960

Query: 960  LGQRSLPISLVFLVPVRLNQTVIWDRPQVTFSENLSSTCHTKERLPSHSDFLAELRKAPV 1019
            LGQRSLPISLVFLVPVRLNQTVIWDRPQVTFSENLSSTCHTKERLPSHSDFLAELRKAPV
Sbjct: 961  LGQRSLPISLVFLVPVRLNQTVIWDRPQVTFSENLSSTCHTKERLPSHSDFLAELRKAPV 1020

Query: 1020 VNCSIAVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYIKTSHNHLLIVSTAEILFNDSVF 1079
            VNCSIAVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYIKTSHNHLLIVSTAEILFNDSVF
Sbjct: 1021 VNCSIAVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYIKTSHNHLLIVSTAEILFNDSVF 1080

Query: 1080 TLLPGQGAFVRSQTETKVEPFEVPNPLPLIVGSSVGGLLLLALITAALYKLGFFKRQYKD 1139
            TLLPGQGAFVRSQTETKVEPFEVPNPLPLIVGSSVGGLLLLALITAALYKLGFFKRQYKD
Sbjct: 1081 TLLPGQGAFVRSQTETKVEPFEVPNPLPLIVGSSVGGLLLLALITAALYKLGFFKRQYKD 1140

Query: 1140 MMSEGGPPGAEPQ 1152
            MMSEGGPPGAEPQ
Sbjct: 1141 MMSEGGPPGAEPQ 1153


>gi|34452173 integrin alpha X precursor [Homo sapiens]
          Length = 1163

 Score = 1358 bits (3515), Expect = 0.0
 Identities = 701/1140 (61%), Positives = 839/1140 (73%), Gaps = 5/1140 (0%)

Query: 5    VLLLTALTLCHGFNLDTENAMTFQENARGFGQSVVQLQGSRVVVGAPQEIVAANQRGSLY 64
            +LL TAL    GFNLDTE    F+ ++ GFG SVVQ   S VVVGAPQ+I AANQ G LY
Sbjct: 8    LLLFTALATSLGFNLDTEELTAFRVDSAGFGDSVVQYANSWVVVGAPQKITAANQTGGLY 67

Query: 65   QCDYSTGSCEPIRLQVPVEAVNMSLGLSLAATTSPPQLLACGPTVHQTCSENTYVKGLCF 124
            QC YSTG+CEPI LQVP EAVNMSLGLSLA+TTSP QLLACGPTVH  C  N Y+ GLCF
Sbjct: 68   QCGYSTGACEPIGLQVPPEAVNMSLGLSLASTTSPSQLLACGPTVHHECGRNMYLTGLCF 127

Query: 125  LFGSNLRQQPQKFPEALRGCPQEDSDIAFLIDGSGSIIPHDFRRMKEFVSTVMEQLKKSK 184
            L G    Q  Q+ P + + CP+++ DI FLIDGSGSI   +F  M  FV  V+ Q ++  
Sbjct: 128  LLGPT--QLTQRLPVSRQECPRQEQDIVFLIDGSGSISSRNFATMMNFVRAVISQFQRPS 185

Query: 185  TLFSLMQYSEEFRIHFTFKEFQNNPNPRSLVKPITQLLGRTHTATGIRKVVRELFNITNG 244
            T FSLMQ+S +F+ HFTF+EF+ + NP SL+  + QL G T+TAT I+ VV  LF+ + G
Sbjct: 186  TQFSLMQFSNKFQTHFTFEEFRRSSNPLSLLASVHQLQGFTYTATAIQNVVHRLFHASYG 245

Query: 245  ARKNAFKILVVITDGEKFGDPLGYEDVIPEADREGVIRYVIGVGDAFRSEKSRQELNTIA 304
            AR++A KIL+VITDG+K GD L Y+DVIP AD  G+IRY IGVG AF++  S +ELN IA
Sbjct: 246  ARRDAAKILIVITDGKKEGDSLDYKDVIPMADAAGIIRYAIGVGLAFQNRNSWKELNDIA 305

Query: 305  SKPPRDHVFQVNNFEALKTIQNQLREKIFAIEGTQTGSSSSFEHEMSQEGFSAAITSNGP 364
            SKP ++H+F+V +F+ALK IQNQL+EKIFAIEGT+T SSSSFE EM+QEGFSA  T +GP
Sbjct: 306  SKPSQEHIFKVEDFDALKDIQNQLKEKIFAIEGTETTSSSSFELEMAQEGFSAVFTPDGP 365

Query: 365  LLSTVGSYDWAGGVFLYTSKEKSTFINMTRVDSDMNDAYLGYAAAIILRNRVQSLVLGAP 424
            +L  VGS+ W+GG FLY      TFINM++ + DM D+YLGY+  + L   VQSLVLGAP
Sbjct: 366  VLGAVGSFTWSGGAFLYPPNMSPTFINMSQENVDMRDSYLGYSTELALWKGVQSLVLGAP 425

Query: 425  RYQHIGLVAMFRQNTGMWESNANVKGTQIGAYFGASLCSVDVDSNGSTDLVLIGAPHYYE 484
            RYQH G   +F Q +  W   A V GTQIG+YFGASLCSVDVDS+GSTDLVLIGAPHYYE
Sbjct: 426  RYQHTGKAVIFTQVSRQWRMKAEVTGTQIGSYFGASLCSVDVDSDGSTDLVLIGAPHYYE 485

Query: 485  QTRGGQVSVCPLPRGRARWQCDAVLYGEQGQPWGRFGAALTVLGDVNGDKLTDVAIGAPG 544
            QTRGGQVSVCPLPRG  RW CDAVLYGEQG PWGRFGAALTVLGDVNGDKLTDV IGAPG
Sbjct: 486  QTRGGQVSVCPLPRGWRRWWCDAVLYGEQGHPWGRFGAALTVLGDVNGDKLTDVVIGAPG 545

Query: 545  EEDNRGAVYLFHGTSGSGISPSHSQRIAGSKLSPRLQYFGQSLSGGQDLTMDGLVDLTVG 604
            EE+NRGAVYLFHG  G  ISPSHSQRIAGS+LS RLQYFGQ+LSGGQDLT DGLVDL VG
Sbjct: 546  EEENRGAVYLFHGVLGPSISPSHSQRIAGSQLSSRLQYFGQALSGGQDLTQDGLVDLAVG 605

Query: 605  AQGHVLLLRSQPVLRVKAIMEFNPREVARNVFECNDQVVKGKEAGEVRVCLHVQKSTRDR 664
            A+G VLLLR++PVL V   M+F P E+ R+ FEC +QVV  +   +  +CL++ K +++ 
Sbjct: 606  ARGQVLLLRTRPVLWVGVSMQFIPAEIPRSAFECREQVVSEQTLVQSNICLYIDKRSKNL 665

Query: 665  LREGQIQSVVTYDLALDSGRPHSRAVFNETKNSTRRQTQVLGLTQTCETLKLQLPNCIED 724
            L    +QS VT DLALD GR   RA F ETKN +  + +VLGL   CE   L LP+C+ED
Sbjct: 666  LGSRDLQSSVTLDLALDPGRLSPRATFQETKNRSLSRVRVLGLKAHCENFNLLLPSCVED 725

Query: 725  PVSPIVLRLNFSLVGTPLSAFGNLRPVLAEDAQRLFTALFPFEKNCGNDNICQDDLSITF 784
             V+PI LRLNF+LVG PL AF NLRP+LA DAQR FTA  PFEKNCG D+ICQD+L I+F
Sbjct: 726  SVTPITLRLNFTLVGKPLLAFRNLRPMLAADAQRYFTASLPFEKNCGADHICQDNLGISF 785

Query: 785  SFMSLDCLVVGGPREFNVTVTVRNDGEDSYRTQVTFFFPLDLSYRKVSTLQNQRSQRSWR 844
            SF  L  L+VG   E N  V V NDGEDSY T +TF  P  LSYR V+  Q Q   RS  
Sbjct: 786  SFPGLKSLLVGSNLELNAEVMVWNDGEDSYGTTITFSHPAGLSYRYVAEGQKQGQLRSLH 845

Query: 845  LACESASSTEVSGALKSTSCSINHPIFPENSEVTFNITFDVDSKASLGNKLLLKANVTSE 904
            L C+SA     S    STSC INH IF   +++TF  TFDV  KA LG++LLL ANV+SE
Sbjct: 846  LTCDSAPVG--SQGTWSTSCRINHLIFRGGAQITFLATFDVSPKAVLGDRLLLTANVSSE 903

Query: 905  NNMPRTNKTEFQLELPVKYAVYMVVTSHGVSTKYLNFTAS-ENTSRVMQHQYQVSNLGQR 963
            NN PRT+KT FQLELPVKYAVY VV+SH   TKYLNF+ S E  S V  H+YQV+NLGQR
Sbjct: 904  NNTPRTSKTTFQLELPVKYAVYTVVSSHEQFTKYLNFSESEEKESHVAMHRYQVNNLGQR 963

Query: 964  SLPISLVFLVPVRLNQTVIWDRPQVTFSENLSSTCHTKERLPSHSDFLAELRKAPVVNCS 1023
             LP+S+ F VPV LNQ  +W   +V+  +N S  C +++  P  SDFLA ++K PV++CS
Sbjct: 964  DLPVSINFWVPVELNQEAVWMDVEVSHPQNPSLRCSSEKIAPPASDFLAHIQKNPVLDCS 1023

Query: 1024 IAVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYIKTSHNHLLIVSTAEILFNDSVFTLLP 1083
            IA C R +CD+P F +QEE + TLKGNLSF W  +     + +VS AEI F+ SV++ LP
Sbjct: 1024 IAGCLRFRCDVPSFSVQEELDFTLKGNLSFGWVRQILQKKVSVVSVAEITFDTSVYSQLP 1083

Query: 1084 GQGAFVRSQTETKVEPFEVPNPLPLIVGSSVGGLLLLALITAALYKLGFFKRQYKDMMSE 1143
            GQ AF+R+QT T +E ++V NP PLIVGSS+GGLLLLALITA LYK+GFFKRQYK+MM E
Sbjct: 1084 GQEAFMRAQTTTVLEKYKVHNPTPLIVGSSIGGLLLLALITAVLYKVGFFKRQYKEMMEE 1143


>gi|62548866 integrin, alpha D precursor [Homo sapiens]
          Length = 1161

 Score = 1329 bits (3440), Expect = 0.0
 Identities = 683/1140 (59%), Positives = 845/1140 (74%), Gaps = 8/1140 (0%)

Query: 5    VLLLTALTLCHGFNLDTENAMTFQENARGFGQSVVQLQGSRVVVGAPQEIVAANQRGSLY 64
            VLLL+ L   HGFNLD E    FQE+A GFGQSVVQ  GSR+VVGAP E+VAANQ G LY
Sbjct: 6    VLLLSVLASYHGFNLDVEEPTIFQEDAGGFGQSVVQFGGSRLVVGAPLEVVAANQTGRLY 65

Query: 65   QCDYSTGSCEPIRLQVPVEAVNMSLGLSLAATTSPPQLLACGPTVHQTCSENTYVKGLCF 124
             C  +TG C+PI L +  EAVNMSLGL+LAA+T+  +LLACGPT+H+ C EN+Y KG C 
Sbjct: 66   DCAAATGMCQPIPLHIRPEAVNMSLGLTLAASTNGSRLLACGPTLHRVCGENSYSKGSCL 125

Query: 125  LFGSNLRQQPQKFPEALRGCPQEDSDIAFLIDGSGSIIPHDFRRMKEFVSTVMEQLKKSK 184
            L GS   +  Q  P+A   CP ++ DI FLIDGSGSI  +DF +MK FV  VM Q + + 
Sbjct: 126  LLGSRW-EIIQTVPDATPECPHQEMDIVFLIDGSGSIDQNDFNQMKGFVQAVMGQFEGTD 184

Query: 185  TLFSLMQYSEEFRIHFTFKEFQNNPNPRSLVKPITQLLGRTHTATGIRKVVRELFNITNG 244
            TLF+LMQYS   +IHFTF +F+ +P+ +SLV PI QL G T TATGI  VV +LF+  NG
Sbjct: 185  TLFALMQYSNLLKIHFTFTQFRTSPSQQSLVDPIVQLKGLTFTATGILTVVTQLFHHKNG 244

Query: 245  ARKNAFKILVVITDGEKFGDPLGYEDVIPEADREGVIRYVIGVGDAFRSEKSRQELNTIA 304
            ARK+A KIL+VITDG+K+ DPL Y DVIP+A++ G+IRY IGVG AF+   +RQELNTI+
Sbjct: 245  ARKSAKKILIVITDGQKYKDPLEYSDVIPQAEKAGIIRYAIGVGHAFQGPTARQELNTIS 304

Query: 305  SKPPRDHVFQVNNFEALKTIQNQLREKIFAIEGTQTGSSSSFEHEMSQEGFSAAITSNGP 364
            S PP+DHVF+V+NF AL +IQ QL+EKI+A+EGTQ+ +SSSF+HEMSQEGFS A+T +G 
Sbjct: 305  SAPPQDHVFKVDNFAALGSIQKQLQEKIYAVEGTQSRASSSFQHEMSQEGFSTALTMDGL 364

Query: 365  LLSTVGSYDWAGGVFLYTSKEKSTFINMTRVDSDMNDAYLGYAAAIILRNRVQSLVLGAP 424
             L  VGS+ W+GG FLY      TFINM++ + DM D+YLGY+  + L   VQ+LVLGAP
Sbjct: 365  FLGAVGSFSWSGGAFLYPPNMSPTFINMSQENVDMRDSYLGYSTELALWKGVQNLVLGAP 424

Query: 425  RYQHIGLVAMFRQNTGMWESNANVKGTQIGAYFGASLCSVDVDSNGSTDLVLIGAPHYYE 484
            RYQH G   +F Q +  W   A V GTQIG+YFGASLCSVDVDS+GSTDL+LIGAPHYYE
Sbjct: 425  RYQHTGKAVIFTQVSRQWRKKAEVTGTQIGSYFGASLCSVDVDSDGSTDLILIGAPHYYE 484

Query: 485  QTRGGQVSVCPLPRGRARWQCDAVLYGEQGQPWGRFGAALTVLGDVNGDKLTDVAIGAPG 544
            QTRGGQVSVCPLPRGR +WQCDAVL GEQG PWGRFGAALTVLGDVN DKL DVAIGAPG
Sbjct: 485  QTRGGQVSVCPLPRGRVQWQCDAVLRGEQGHPWGRFGAALTVLGDVNEDKLIDVAIGAPG 544

Query: 545  EEDNRGAVYLFHGTSGSGISPSHSQRIAGSKLSPRLQYFGQSLSGGQDLTMDGLVDLTVG 604
            E++NRGAVYLFHG S SGISPSHSQRIA S+LSPRLQYFGQ+LSGGQDLT DGL+DL VG
Sbjct: 545  EQENRGAVYLFHGASESGISPSHSQRIASSQLSPRLQYFGQALSGGQDLTQDGLMDLAVG 604

Query: 605  AQGHVLLLRSQPVLRVKAIMEFNPREVARNVFECNDQVVKGKEAGEVRVCLHVQKSTRDR 664
            A+G VLLLRS PVL+V   M F+P EVA+ V+ C ++     EAG+  VCL +QKS+ D+
Sbjct: 605  ARGQVLLLRSLPVLKVGVAMRFSPVEVAKAVYRCWEEKPSALEAGDATVCLTIQKSSLDQ 664

Query: 665  LREGQIQSVVTYDLALDSGRPHSRAVFNETKNSTRRQTQVLGLTQTCETLKLQLPNCIED 724
            L  G IQS V +DLALD GR  SRA+FNETKN T  + + LGL   CETLKL LP+C+ED
Sbjct: 665  L--GDIQSSVRFDLALDPGRLTSRAIFNETKNPTLTRRKTLGLGIHCETLKLLLPDCVED 722

Query: 725  PVSPIVLRLNFSLVGTPLSAFGNLRPVLAEDAQRLFTALFPFEKNCGNDNICQDDLSITF 784
             VSPI+L LNFSLV  P+ +  NLRPVLA  +Q LFTA  PFEKNCG D +C+ DL +T 
Sbjct: 723  VVSPIILHLNFSLVREPIPSPQNLRPVLAVGSQDLFTASLPFEKNCGQDGLCEGDLGVTL 782

Query: 785  SFMSLDCLVVGGPREFNVTVTVRNDGEDSYRTQVTFFFPLDLSYRKVSTLQNQRSQRSWR 844
            SF  L  L VG   E NV VTV N GEDSY T V+ ++P  LS+R+VS  Q Q  Q + R
Sbjct: 783  SFSGLQTLTVGSSLELNVIVTVWNAGEDSYGTVVSLYYPAGLSHRRVSGAQKQPHQSALR 842

Query: 845  LACESASSTEVSGALKSTSCSINHPIFPENSEVTFNITFDVDSKASLGNKLLLKANVTSE 904
            LACE+   TE  G L+S+ CS+NHPIF E S  TF +TFDV  KA+LG+++L++A+ +SE
Sbjct: 843  LACETV-PTEDEG-LRSSRCSVNHPIFHEGSNGTFIVTFDVSYKATLGDRMLMRASASSE 900

Query: 905  NNMPRTNKTEFQLELPVKYAVYMVVTSHGVSTKYLNF-TASENTSRVMQHQYQVSNLGQR 963
            NN   ++K  FQLELPVKYAVY +++    STKY NF T+ E   +  +H+Y+V+NL QR
Sbjct: 901  NNKASSSKATFQLELPVKYAVYTMISRQEESTKYFNFATSDEKKMKEAEHRYRVNNLSQR 960

Query: 964  SLPISLVFLVPVRLNQTVIWDRPQVTFSENLSSTCHTKERLPSHSDFLAELRKAPVVNCS 1023
             L IS+ F VPV LN   +WD      S++L   C ++ + P HSDFL ++ ++P+++CS
Sbjct: 961  DLAISINFWVPVLLNGVAVWDVVMEAPSQSL--PCVSERKPPQHSDFLTQISRSPMLDCS 1018

Query: 1024 IAVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYIKTSHNHLLIVSTAEILFNDSVFTLLP 1083
            IA C + +CD+P F +QEE + TLKGNLSF W  +T    +L+VS AEI F+ SV++ LP
Sbjct: 1019 IADCLQFRCDVPSFSVQEELDFTLKGNLSFGWVRETLQKKVLVVSVAEITFDTSVYSQLP 1078

Query: 1084 GQGAFVRSQTETKVEPFEVPNPLPLIVGSSVGGLLLLALITAALYKLGFFKRQYKDMMSE 1143
            GQ AF+R+Q E  +E  EV N +P+I+GSSVG LLLLALITA LYKLGFFKR YK+M+ +
Sbjct: 1079 GQEAFMRAQMEMVLEEDEVYNAIPIIMGSSVGALLLLALITATLYKLGFFKRHYKEMLED 1138


>gi|167466215 integrin alpha L isoform a precursor [Homo sapiens]
          Length = 1170

 Score =  577 bits (1487), Expect = e-164
 Identities = 393/1155 (34%), Positives = 603/1155 (52%), Gaps = 64/1155 (5%)

Query: 17   FNLDTENAMTFQENARG--FGQSVVQLQGSRVVVGAPQEIVAANQRGSLYQCDYSTGSCE 74
            +NLD   A +F     G  FG  V+Q+ G+ V+VGAP E    N  GSLYQC   TG C 
Sbjct: 26   YNLDVRGARSFSPPRAGRHFGYRVLQV-GNGVIVGAPGE---GNSTGSLYQCQSGTGHCL 81

Query: 75   PIRLQVPVEAVNMSLGLSLAATTSPPQLLACGPTVHQTCSENTYVKGLCFLFGSNLRQQP 134
            P+ L+      +  LG++LA   +   +LAC P + +TC +NTY+ GLC+LF  NL+   
Sbjct: 82   PVTLRGS-NYTSKYLGMTLATDPTDGSILACDPGLSRTCDQNTYLSGLCYLFRQNLQGPM 140

Query: 135  QKFPEALRGCPQEDSDIAFLIDGSGSIIPHDFRRMKEFVSTVMEQLKKSKTLFSLMQYSE 194
             +     + C + + D+ FL DGS S+ P +F+++ +F+  VM++L  +   F+ +Q+S 
Sbjct: 141  LQGRPGFQECIKGNVDLVFLFDGSMSLQPDEFQKILDFMKDVMKKLSNTSYQFAAVQFST 200

Query: 195  EFRIHFTFKEFQNNPNPRSLVKPITQLLGRTHTATGIRKVVRELFNITNGARKNAFKILV 254
             ++  F F ++    +P +L+K +  +L  T+T   I  V  E+F    GAR +A K+L+
Sbjct: 201  SYKTEFDFSDYVKRKDPDALLKHVKHMLLLTNTFGAINYVATEVFREELGARPDATKVLI 260

Query: 255  VITDGEKFGDPLGYEDVIPEADREGVIRYVIGVGDAFRSEKSRQELNTIASKPPRDHVFQ 314
            +ITDGE      G  D   +     +IRY+IG+G  F++++S++ L+  ASKP  + V  
Sbjct: 261  IITDGE--ATDSGNIDAAKD-----IIRYIIGIGKHFQTKESQETLHKFASKPASEFVKI 313

Query: 315  VNNFEALKTIQNQLREKIFAIEGTQTGSSSSFEHEMSQEGFSAAITSNGPLLSTVGSYDW 374
            ++ FE LK +  +L++KI+ IEGT     +SF  E+S  G SA ++    ++  VG+ DW
Sbjct: 314  LDTFEKLKDLFTELQKKIYVIEGTSKQDLTSFNMELSSSGISADLSRGHAVVGAVGAKDW 373

Query: 375  AGGVF-LYTSKEKSTFINMTRVDSDMNDAYLGYAAA-IILRNRVQSLVLGAPRYQHIGLV 432
            AGG   L    +  TFI    +  ++   YLGY    +  R +   L  GAPRYQH+G V
Sbjct: 374  AGGFLDLKADLQDDTFIGNEPLTPEVRAGYLGYTVTWLPSRQKTSLLASGAPRYQHMGRV 433

Query: 433  AMFR--QNTGMWESNANVKGTQIGAYFGASLCSVDVDSNGSTDLVLIGAPHYYEQTRGGQ 490
             +F+  Q  G W     + GTQIG+YFG  LC VDVD +G T+L+LIGAP +Y + RGG+
Sbjct: 434  LLFQEPQGGGHWSQVQTIHGTQIGSYFGGELCGVDVDQDGETELLLIGAPLFYGEQRGGR 493

Query: 491  VSVCPLPRGRARWQCDAVLYGEQGQPWGRFGAALTVLGDVNGDKLTDVAIGAPGEEDNRG 550
            V +    R +  ++  + L G+ G P GRFG A+T L D+NGD L DVA+GAP EE  +G
Sbjct: 494  VFI--YQRRQLGFEEVSELQGDPGYPLGRFGEAITALTDINGDGLVDVAVGAPLEE--QG 549

Query: 551  AVYLFHGTSGSGISPSHSQRIAGSKLSPRLQYFGQSLSGGQDLTMDGLVDLTVGAQGHVL 610
            AVY+F+G  G G+SP  SQRI G+++   +Q+FG+S+ G +DL  DGL D+ VGA+  ++
Sbjct: 550  AVYIFNGRHG-GLSPQPSQRIEGTQVLSGIQWFGRSIHGVKDLEGDGLADVAVGAESQMI 608

Query: 611  LLRSQPVLRVKAIMEFNPREVARNVFECNDQVV-KGKEAGEVRVCLHVQKSTRDRLREGQ 669
            +L S+PV+ +  +M F+P E+  +  EC+     K KE   + +C  + KS   +  +G+
Sbjct: 609  VLSSRPVVDMVTLMSFSPAEIPVHEVECSYSTSNKMKEGVNITICFQI-KSLIPQF-QGR 666

Query: 670  IQSVVTYDLALDSGRPHSRAVFNETKNSTRRQTQVLGLTQTCETLKLQLPNCIEDPVSPI 729
            + + +TY L LD  R   R +F   ++  RR   V   + +C       P C++D +SPI
Sbjct: 667  LVANLTYTLQLDGHRTRRRGLFPGGRHELRRNIAVT-TSMSCTDFSFHFPVCVQDLISPI 725

Query: 730  VLRLNFSL---VGTPLS--AFGNLRPVLAEDAQRLFTALFPFEKNCGNDNICQDDLSITF 784
             + LNFSL    GTP    A G   P +   +    T   PFEKNCG D  C+ +L ++F
Sbjct: 726  NVSLNFSLWEEEGTPRDQRAQGKDIPPILRPSLHSETWEIPFEKNCGEDKKCEANLRVSF 785

Query: 785  SFMSLDCLVVGGPREFNVTVTVRNDGEDSYRTQVTFFFPLDLSYRKVSTLQNQRSQRSWR 844
            S      L +      +V +++ N  ED+Y  Q+   FP  LS+RKV  L   +      
Sbjct: 786  SPARSRALRLTAFASLSVELSLSNLEEDAYWVQLDLHFPPGLSFRKVEML---KPHSQIP 842

Query: 845  LACESASSTEVSGALKSTSCSINHPIFPENSEVTFNITFDVDSKASLGNKLLLKANVTSE 904
            ++CE     E     ++ SC+++ PIF     V   + F+    +S G+ + L ANVT  
Sbjct: 843  VSCEELPE-ESRLLSRALSCNVSSPIFKAGHSVALQMMFNTLVNSSWGDSVELHANVTCN 901

Query: 905  N-NMPRTNKTEFQLELPVKYAVYMVVTSHGVSTKYLNFTASENTSRVMQHQYQV---SNL 960
            N +            +P+ Y + +++     ST Y++FT        ++H YQV    ++
Sbjct: 902  NEDSDLLEDNSATTIIPILYPINILIQDQEDSTLYVSFTPKGPKIHQVKHMYQVRIQPSI 961

Query: 961  GQRSLP-ISLVFLVPVRLNQTVIWDRPQVTFSENLSSTCHTKERLPSHSD--FLAELRKA 1017
               ++P +  V  VP   ++  I  +  V     +       ERLP  ++      L + 
Sbjct: 962  HDHNIPTLEAVVGVPQPPSEGPITHQWSVQMEPPVPCHYEDLERLPDAAEPCLPGALFRC 1021

Query: 1018 PVVNCSIAVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYIKTSHNHLLIVSTAEILFNDS 1077
            PVV                   ++E    + G L     I+ S +   + S+  I FN S
Sbjct: 1022 PVV------------------FRQEILVQVIGTLELVGEIEAS-SMFSLCSSLSISFNSS 1062

Query: 1078 VFTLLPGQGAFVRSQTETKVEPFEVPNPLPLIVGSSVGGLLLLALITAALYKLGFFKRQY 1137
                L G  A + +Q   KV+       L L V S +GGLLLL LI   LYK+GFFKR  
Sbjct: 1063 KHFHLYGSNASL-AQVVMKVDVVYEKQMLYLYVLSGIGGLLLLLLIFIVLYKVGFFKRNL 1121

Query: 1138 KDMMSEG-GPPGAEP 1151
            K+ M  G G P   P
Sbjct: 1122 KEKMEAGRGVPNGIP 1136


>gi|167466217 integrin alpha L isoform b precursor [Homo sapiens]
          Length = 1086

 Score =  473 bits (1217), Expect = e-133
 Identities = 340/1033 (32%), Positives = 520/1033 (50%), Gaps = 63/1033 (6%)

Query: 143  GCPQEDSDIAFLID---GSGSIIPHDFR----RMKEFVSTVMEQLKKSKTLFSLMQYSEE 195
            G P E +    L     G+G  +P   R      K    T+         LF+ +Q+S  
Sbjct: 59   GAPGEGNSTGSLYQCQSGTGHCLPVTLRGSNYTSKYLGMTLATDPTDGSILFAAVQFSTS 118

Query: 196  FRIHFTFKEFQNNPNPRSLVKPITQLLGRTHTATGIRKVVRELFNITNGARKNAFKILVV 255
            ++  F F ++    +P +L+K +  +L  T+T   I  V  E+F    GAR +A K+L++
Sbjct: 119  YKTEFDFSDYVKRKDPDALLKHVKHMLLLTNTFGAINYVATEVFREELGARPDATKVLII 178

Query: 256  ITDGEKFGDPLGYEDVIPEADREGVIRYVIGVGDAFRSEKSRQELNTIASKPPRDHVFQV 315
            ITDGE      G  D   +     +IRY+IG+G  F++++S++ L+  ASKP  + V  +
Sbjct: 179  ITDGEATDS--GNIDAAKD-----IIRYIIGIGKHFQTKESQETLHKFASKPASEFVKIL 231

Query: 316  NNFEALKTIQNQLREKIFAIEGTQTGSSSSFEHEMSQEGFSAAITSNGPLLSTVGSYDWA 375
            + FE LK +  +L++KI+ IEGT     +SF  E+S  G SA ++    ++  VG+ DWA
Sbjct: 232  DTFEKLKDLFTELQKKIYVIEGTSKQDLTSFNMELSSSGISADLSRGHAVVGAVGAKDWA 291

Query: 376  GGVF-LYTSKEKSTFINMTRVDSDMNDAYLGYAAA-IILRNRVQSLVLGAPRYQHIGLVA 433
            GG   L    +  TFI    +  ++   YLGY    +  R +   L  GAPRYQH+G V 
Sbjct: 292  GGFLDLKADLQDDTFIGNEPLTPEVRAGYLGYTVTWLPSRQKTSLLASGAPRYQHMGRVL 351

Query: 434  MFR--QNTGMWESNANVKGTQIGAYFGASLCSVDVDSNGSTDLVLIGAPHYYEQTRGGQV 491
            +F+  Q  G W     + GTQIG+YFG  LC VDVD +G T+L+LIGAP +Y + RGG+V
Sbjct: 352  LFQEPQGGGHWSQVQTIHGTQIGSYFGGELCGVDVDQDGETELLLIGAPLFYGEQRGGRV 411

Query: 492  SVCPLPRGRARWQCDAVLYGEQGQPWGRFGAALTVLGDVNGDKLTDVAIGAPGEEDNRGA 551
             +    R +  ++  + L G+ G P GRFG A+T L D+NGD L DVA+GAP EE  +GA
Sbjct: 412  FI--YQRRQLGFEEVSELQGDPGYPLGRFGEAITALTDINGDGLVDVAVGAPLEE--QGA 467

Query: 552  VYLFHGTSGSGISPSHSQRIAGSKLSPRLQYFGQSLSGGQDLTMDGLVDLTVGAQGHVLL 611
            VY+F+G  G G+SP  SQRI G+++   +Q+FG+S+ G +DL  DGL D+ VGA+  +++
Sbjct: 468  VYIFNGRHG-GLSPQPSQRIEGTQVLSGIQWFGRSIHGVKDLEGDGLADVAVGAESQMIV 526

Query: 612  LRSQPVLRVKAIMEFNPREVARNVFECNDQVV-KGKEAGEVRVCLHVQKSTRDRLREGQI 670
            L S+PV+ +  +M F+P E+  +  EC+     K KE   + +C  + KS   +  +G++
Sbjct: 527  LSSRPVVDMVTLMSFSPAEIPVHEVECSYSTSNKMKEGVNITICFQI-KSLIPQF-QGRL 584

Query: 671  QSVVTYDLALDSGRPHSRAVFNETKNSTRRQTQVLGLTQTCETLKLQLPNCIEDPVSPIV 730
             + +TY L LD  R   R +F   ++  RR   V   + +C       P C++D +SPI 
Sbjct: 585  VANLTYTLQLDGHRTRRRGLFPGGRHELRRNIAVT-TSMSCTDFSFHFPVCVQDLISPIN 643

Query: 731  LRLNFSL---VGTPL-SAFGNLRPVLAEDAQRLFTALFPFEKNCGNDNICQDDLSITFSF 786
            + LNFSL    GTP     G   P +   +    T   PFEKNCG D  C+ +L ++FS 
Sbjct: 644  VSLNFSLWEEEGTPRDQRAGKDIPPILRPSLHSETWEIPFEKNCGEDKKCEANLRVSFSP 703

Query: 787  MSLDCLVVGGPREFNVTVTVRNDGEDSYRTQVTFFFPLDLSYRKVSTLQNQRSQRSWRLA 846
                 L +      +V +++ N  ED+Y  Q+   FP  LS+RKV  L   +      ++
Sbjct: 704  ARSRALRLTAFASLSVELSLSNLEEDAYWVQLDLHFPPGLSFRKVEML---KPHSQIPVS 760

Query: 847  CESASSTEVSGALKSTSCSINHPIFPENSEVTFNITFDVDSKASLGNKLLLKANVTSEN- 905
            CE     E     ++ SC+++ PIF     V   + F+    +S G+ + L ANVT  N 
Sbjct: 761  CEELPE-ESRLLSRALSCNVSSPIFKAGHSVALQMMFNTLVNSSWGDSVELHANVTCNNE 819

Query: 906  NMPRTNKTEFQLELPVKYAVYMVVTSHGVSTKYLNFTASENTSRVMQHQYQV---SNLGQ 962
            +            +P+ Y + +++     ST Y++FT        ++H YQV    ++  
Sbjct: 820  DSDLLEDNSATTIIPILYPINILIQDQEDSTLYVSFTPKGPKIHQVKHMYQVRIQPSIHD 879

Query: 963  RSLP-ISLVFLVPVRLNQTVIWDRPQVTFSENLSSTCHTKERLPSHSD--FLAELRKAPV 1019
             ++P +  V  VP   ++  I  +  V     +       ERLP  ++      L + PV
Sbjct: 880  HNIPTLEAVVGVPQPPSEGPITHQWSVQMEPPVPCHYEDLERLPDAAEPCLPGALFRCPV 939

Query: 1020 VNCSIAVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYIKTSHNHLLIVSTAEILFNDSVF 1079
            V                   ++E    + G L     I+ S +   + S+  I FN S  
Sbjct: 940  V------------------FRQEILVQVIGTLELVGEIEAS-SMFSLCSSLSISFNSSKH 980

Query: 1080 TLLPGQGAFVRSQTETKVEPFEVPNPLPLIVGSSVGGLLLLALITAALYKLGFFKRQYKD 1139
              L G  A + +Q   KV+       L L V S +GGLLLL LI   LYK+GFFKR  K+
Sbjct: 981  FHLYGSNASL-AQVVMKVDVVYEKQMLYLYVLSGIGGLLLLLLIFIVLYKVGFFKRNLKE 1039

Query: 1140 MMSEG-GPPGAEP 1151
             M  G G P   P
Sbjct: 1040 KMEAGRGVPNGIP 1052



 Score = 58.2 bits (139), Expect = 5e-08
 Identities = 132/529 (24%), Positives = 213/529 (40%), Gaps = 100/529 (18%)

Query: 17  FNLDTENAMTFQENARG--FGQSVVQLQGSRVVVGAPQEIVAANQRGSLYQCDYSTGSCE 74
           +NLD   A +F     G  FG  V+Q+ G+ V+VGAP E    N  GSLYQC   TG C 
Sbjct: 26  YNLDVRGARSFSPPRAGRHFGYRVLQV-GNGVIVGAPGE---GNSTGSLYQCQSGTGHCL 81

Query: 75  PIRLQVPVEAVNMSLGLSLAATTSPPQLLACG---PTVHQTCSE-NTYVKG--------- 121
           P+ L+      +  LG++LA   +   +L       T ++T  + + YVK          
Sbjct: 82  PVTLR-GSNYTSKYLGMTLATDPTDGSILFAAVQFSTSYKTEFDFSDYVKRKDPDALLKH 140

Query: 122 ------LCFLFGSNLRQQPQKFPEALRGCPQEDSDIAFLIDG----SGSI---------- 161
                 L   FG+      + F E L   P     +  + DG    SG+I          
Sbjct: 141 VKHMLLLTNTFGAINYVATEVFREELGARPDATKVLIIITDGEATDSGNIDAAKDIIRYI 200

Query: 162 --------------IPHDF--RRMKEFVSTVMEQLKKSKTLFSLMQYSEEFRIHFTFKEF 205
                           H F  +   EFV  +++  +K K LF+ +Q  + + I  T K+ 
Sbjct: 201 IGIGKHFQTKESQETLHKFASKPASEFVK-ILDTFEKLKDLFTELQ-KKIYVIEGTSKQD 258

Query: 206 QNNPNPRSLVKPITQLLGRTHTATGIRKVVRELFNITNGARKNAFKILVVITDGEKFGDP 265
             + N       I+  L R H   G             GA+  A   L +  D +     
Sbjct: 259 LTSFNMELSSSGISADLSRGHAVVG-----------AVGAKDWAGGFLDLKADLQD-DTF 306

Query: 266 LGYEDVIPEADREGVIRYVIGVGDAFRSEKSRQELNTIASKPPR-DHVFQVNNFEALKTI 324
           +G E + PE  R G + Y +          SRQ+ + +AS  PR  H+ +V  F+  +  
Sbjct: 307 IGNEPLTPEV-RAGYLGYTV------TWLPSRQKTSLLASGAPRYQHMGRVLLFQEPQGG 359

Query: 325 QNQLREKIFAIEGTQTGSSSSFE---HEMSQEGFSAAITSNGPLLSTVGSYDWAGGVFLY 381
            +    ++  I GTQ GS    E    ++ Q+G +  +    PL          G VF+Y
Sbjct: 360 GHW--SQVQTIHGTQIGSYFGGELCGVDVDQDGETELLLIGAPLFY---GEQRGGRVFIY 414

Query: 382 TSKEKSTFINMTRVDSDMNDAYLGYAAAI-----ILRNRVQSLVLGAPRYQHIGLVAMFR 436
             ++   F  ++ +  D       +  AI     I  + +  + +GAP  +  G V +F 
Sbjct: 415 QRRQLG-FEEVSELQGDPGYPLGRFGEAITALTDINGDGLVDVAVGAP-LEEQGAVYIFN 472

Query: 437 QNTG--MWESNANVKGTQIGA---YFGASLCSV-DVDSNGSTDLVLIGA 479
              G    + +  ++GTQ+ +   +FG S+  V D++ +G  D V +GA
Sbjct: 473 GRHGGLSPQPSQRIEGTQVLSGIQWFGRSIHGVKDLEGDGLAD-VAVGA 520


>gi|148728188 integrin, alpha E precursor [Homo sapiens]
          Length = 1179

 Score =  417 bits (1073), Expect = e-116
 Identities = 305/1013 (30%), Positives = 504/1013 (49%), Gaps = 69/1013 (6%)

Query: 149  SDIAFLIDGSGSIIPHDFRRMKEFVSTVMEQL--KKSKTLFSLMQYSEEFRIHFTFKEFQ 206
            ++IA ++DGSGSI P DF+R K+F+S +M     K  +  F+L+QY    +  F  ++ Q
Sbjct: 201  TEIAIILDGSGSIDPPDFQRAKDFISNMMRNFYEKCFECNFALVQYGGVIQTEFDLRDSQ 260

Query: 207  NNPNPRSLVKPITQLLGRTHTATGIRKVVRELFNITNGARKNAFKILVVITDGEKFGDPL 266
            +     + V+ ITQ+   T TA+ ++ V+  +F  ++G+R+ A K++VV+TDG  F DPL
Sbjct: 261  DVMASLARVQNITQVGSVTKTASAMQHVLDSIFTSSHGSRRKASKVMVVLTDGGIFEDPL 320

Query: 267  GYEDVIPEADREGVIRYVIGVGDAFRSEKSRQELNTIASKPPRDHVFQVNNFEALKTIQN 326
                VI     +GV R+ IGVG+ F+S ++ +ELN IAS P   H F+V N+ AL  + +
Sbjct: 321  NLTTVINSPKMQGVERFAIGVGEEFKSARTARELNLIASDPDETHAFKVTNYMALDGLLS 380

Query: 327  QLREKIFAIEGTQTGSSSSFEHEMSQEGFSAAITSNGP-LLSTVGSYDWAGGVFLY-TSK 384
            +LR  I ++EGT      +  ++++Q GFSA I      LL  VG++DW+GG  LY T  
Sbjct: 381  KLRYNIISMEGT---VGDALHYQLAQIGFSAQILDERQVLLGAVGAFDWSGGALLYDTRS 437

Query: 385  EKSTFINMTRVDSDMNDA----YLGYAAAIILRNRVQSLVLGAPRYQHIGLVAMFRQNTG 440
             +  F+N T   +   +A    YLGYA A++ +    S + GAPRY+H G V   ++   
Sbjct: 438  RRGRFLNQTAAAAADAEAAQYSYLGYAVAVLHKTCSLSYIAGAPRYKHHGAVFELQKEGR 497

Query: 441  MWESNANVKGTQIGAYFGASLCSVDVDSNGSTDLVLIGAPHYYEQTRGGQVSVCPLPRGR 500
                   ++G Q+G+YFG+ LC VD+D +GSTD +L+ AP Y+     G+V V  L    
Sbjct: 498  EASFLPVLEGEQMGSYFGSELCPVDIDMDGSTDFLLVAAPFYHVHGEEGRVYVYRLSEQD 557

Query: 501  ARWQCDAVLYGEQGQPWGRFGAALTVLGDVNGDKLTDVAIGAP----GEEDNR--GAVYL 554
              +    +L G  G    RFG A+  +GD++ DKLTDVAIGAP    G +D    G+VY+
Sbjct: 558  GSFSLARILSGHPGFTNARFGFAMAAMGDLSQDKLTDVAIGAPLEGFGADDGASFGSVYI 617

Query: 555  FHGTSGSGISPSHSQRIAGSKLSPRLQYFGQSLSGGQDLTMDGLVDLTVGAQGHVLLLRS 614
            ++G    G+S S SQRI  S ++P LQYFG S++GG D++ DGL D+TVG  G  ++ RS
Sbjct: 618  YNG-HWDGLSASPSQRIRASTVAPGLQYFGMSMAGGFDISGDGLADITVGTLGQAVVFRS 676

Query: 615  QPVLRVKAIMEFNPREVARNVFECNDQVVKGKEAGEVRVCLHVQKSTRDRLREGQIQSVV 674
            +PV+R+K  M F P  +           +       VR+C  +  S       G  ++++
Sbjct: 677  RPVVRLKVSMAFTPSALP----------IGFNGVVNVRLCFEI-SSVTTASESGLREALL 725

Query: 675  TYDLALDSGRPHSRAVFNETKNSTRRQTQVLGLTQTCETLKLQLPN----CIEDPVSPIV 730
             + L +D G+   R   ++ ++      +    +Q CE L L +P     C ED  S   
Sbjct: 726  NFTLDVDVGKQRRRLQCSDVRSCLGCLREWSSGSQLCEDL-LLMPTEGELCEEDCFSNAS 784

Query: 731  LRLNFSLVGTPLSAFGNLRPVLAEDAQRLFTALFPFEKNCGNDNICQDDLSITFSFMSLD 790
            +++++ L  TP     + +P+L    +       P+EK C N   C  +L +  + +S  
Sbjct: 785  VKVSYQL-QTPEGQTDHPQPILDRYTEPFAIFQLPYEKACKNKLFCVAELQLA-TTVSQQ 842

Query: 791  CLVVGGPREFNVTVTVRNDGEDSYRTQVTFFFPLDLSYRKVSTLQNQRSQRSWRLACESA 850
             LVVG  +E  + + + N GEDSY T +   +P +L       L+  +   S  + C+  
Sbjct: 843  ELVVGLTKELTLNINLTNSGEDSYMTSMALNYPRNLQ------LKRMQKPPSPNIQCDDP 896

Query: 851  SSTEVSGALKSTSCSINHPIFPENSEVTFNITFDVDSKASLGNKLLLKANVTSENNMPRT 910
                   ++   +C I HP+  + S    ++ + ++  A       +   VT+ N   R 
Sbjct: 897  QPV---ASVLIMNCRIGHPVL-KRSSAHVSVVWQLEENAFPNRTADITVTVTNSNE--RR 950

Query: 911  NKTEFQLELPVKYAVYMVVTSHGVSTKYLNFTASENTSRVMQHQYQVSNLGQRSLPISLV 970
            +       L  ++    V++    S  Y+N    +  S   +  + V           L 
Sbjct: 951  SLANETHTLQFRHGFVAVLSK--PSIMYVN--TGQGLSHHKEFLFHVHGENLFGAEYQLQ 1006

Query: 971  FLVPVRLNQTVIWDRPQVTFSENLSSTCHTKERLPSHSDFLAELRKAPVVNCSIAVCQRI 1030
              VP +L    +    ++T ++  +    ++ER  ++S  +  + +   V+C IA     
Sbjct: 1007 ICVPTKLRGLQVVAVKKLTRTQASTVCTWSQERACAYSS-VQHVEEWHSVSCVIA----- 1060

Query: 1031 QCDIPFFGIQEEFNATLKGNLSFDWYIKTSHNHLLIVSTAEILFNDSVFTLLPGQGAFVR 1090
                      ++ N T+   +S+D   +   +   +    EI FN S++  L  +    R
Sbjct: 1061 ---------SDKENVTVAAEISWDHSEELLKDVTELQILGEISFNKSLYEGLNAENH--R 1109

Query: 1091 SQTETKVEPFEVPNPLPLIVGSSVGGLLLLALITAALYKLGFFKRQYKDMMSE 1143
            ++        E  + LP+I+  SVGGLL+L +I   L+K GFFKR+Y+ +  E
Sbjct: 1110 TKITVVFLKDEKYHSLPIIIKGSVGGLLVLIVILVILFKCGFFKRKYQQLNLE 1162


>gi|239751058 PREDICTED: hypothetical protein XP_002347690 [Homo
            sapiens]
          Length = 462

 Score =  406 bits (1043), Expect = e-113
 Identities = 231/444 (52%), Positives = 279/444 (62%), Gaps = 53/444 (11%)

Query: 751  VLAEDAQRLFTALFPFEKNCGNDNICQDDLSITFSFMSLDCLVVGGPREFNVTVTVRNDG 810
            +LA DAQR FTA  PFEKNCG D+ICQD+L I+FSF  L  L+VG   E N  V V NDG
Sbjct: 1    MLAADAQRYFTASLPFEKNCGADHICQDNLGISFSFPGLKSLLVGSNLELNAEVMVWNDG 60

Query: 811  EDSYRTQVTFFFPLDLSYRKVSTLQNQRSQRSWRLACESASSTEVSGALKSTSCSINHPI 870
            EDSY T +TF  P  LSYR V+  Q Q   RS  L C+SA     S    STSC INH I
Sbjct: 61   EDSYGTTITFSHPAGLSYRYVAEGQKQGQLRSLHLTCDSAPVG--SQGTWSTSCRINHLI 118

Query: 871  FPENSEVTFNITFDVDSKASLGNKLLLKANVTSENNMPRTNKTEFQLELPVKYAVYMVVT 930
            F   +++TF  TFDV  KA LG++LLL ANV+SENN PRT+KT FQLELPVKYAVY VV+
Sbjct: 119  FRGGAQITFLATFDVSPKAVLGDRLLLTANVSSENNTPRTSKTTFQLELPVKYAVYTVVS 178

Query: 931  SHGVSTKYLNFTAS-ENTSRVMQHQYQ-----------VSNLGQRSLPISLVFLVPVRLN 978
            SH   TKYLNF+ S E  S V  H+YQ           V+NLGQR LP+S+ F VPV LN
Sbjct: 179  SHEQFTKYLNFSESEEKESHVAMHRYQAGGGDAGDWAGVNNLGQRDLPVSINFWVPVELN 238

Query: 979  QTVIW-----DRPQV----------------------------------TFSENLSSTCH 999
            Q  +W       PQV                                   F +N S  C 
Sbjct: 239  QEAVWMDVEVSHPQVPKDCMWLLHECPFYLDSLCPMWVPDVPAETLVLCIFPQNPSLRCS 298

Query: 1000 TKERLPSHSDFLAELRKAPVVNCSIAVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYIKT 1059
            +++  P  SDFLA ++K PV++CSIA C R +CD+P F +QEE + TLKGNLSF W  + 
Sbjct: 299  SEKIAPPASDFLAHIQKNPVLDCSIAGCLRFRCDVPSFSVQEELDFTLKGNLSFGWVRQI 358

Query: 1060 SHNHLLIVSTAEILFNDSVFTLLPGQGAFVRSQTETKVEPFEVPNPLPLIVGSSVGGLLL 1119
                + +VS AEI F+ SV++ LPGQ AF+R+QT T +E ++V NP PLIVGSS+GGLLL
Sbjct: 359  LQKKVSVVSVAEITFDTSVYSQLPGQEAFMRAQTTTVLEKYKVHNPTPLIVGSSIGGLLL 418

Query: 1120 LALITAALYKLGFFKRQYKDMMSE 1143
            LALITA LYK+GFFKRQYK+MM E
Sbjct: 419  LALITAVLYKVGFFKRQYKEMMEE 442


>gi|31657142 integrin, alpha 1 precursor [Homo sapiens]
          Length = 1179

 Score =  397 bits (1021), Expect = e-110
 Identities = 346/1214 (28%), Positives = 554/1214 (45%), Gaps = 128/1214 (10%)

Query: 6    LLLTALTLCHGFNLDTENAMTFQENARG-FGQSVVQLQ---GSRVVVGAPQEIVAANQRG 61
            LL   L  C  FN+D +N+MTF       FG +V Q +   G  V++G+P      N+ G
Sbjct: 18   LLTVVLRCCVSFNVDVKNSMTFSGPVEDMFGYTVQQYENEEGKWVLIGSPLVGQPKNRTG 77

Query: 62   SLYQCDYSTGSCEP-IRLQVPVEAV---------NMSLGLSLAATTSPPQLLACGPTVHQ 111
             +Y+C    G   P ++L +PV            NM+ G +L  T      LACGP    
Sbjct: 78   DVYKCPVGRGESLPCVKLDLPVNTSIPNVTEVKENMTFGSTLV-TNPNGGFLACGPLYAY 136

Query: 112  TCSENTYVKGLCFLFGSNLRQQPQKFPEALRGCPQEDSDIAFLIDGSGSIIPHDFRRMKE 171
             C    Y  G+C       +      P  ++ C  +  DI  ++DGS SI P D   +  
Sbjct: 137  RCGHLHYTTGICSDVSPTFQVVNSIAP--VQECSTQ-LDIVIVLDGSNSIYPWD--SVTA 191

Query: 172  FVSTVMEQLK--KSKTLFSLMQYSEEFRIHFTFKEFQNNPNPRSLVKPITQLLGR-THTA 228
            F++ ++E++     +T   ++QY E     F   ++ +        K I Q  GR T TA
Sbjct: 192  FLNDLLERMDIGPKQTQVGIVQYGENVTHEFNLNKYSSTEEVLVAAKKIVQRGGRQTMTA 251

Query: 229  TGIRKVVRELFNITNGARKNAFKILVVITDGEKFGDPLGYEDVIPEADREGVIRYVIGVG 288
             GI    +E F    GAR+   K++V++TDGE   D    + VI + + E + R+ I + 
Sbjct: 252  LGIDTARKEAFTEARGARRGVKKVMVIVTDGESH-DNHRLKKVIQDCEDENIQRFSIAIL 310

Query: 289  DAFR-----SEKSRQELNTIASKPPRDHVFQVNNFEALKTIQNQLREKIFAIEGTQTGSS 343
             ++      +EK  +E+ +IAS+P   H F V++  AL TI   L E+IFA+E T   S+
Sbjct: 311  GSYNRGNLSTEKFVEEIKSIASEPTEKHFFNVSDELALVTIVKTLGERIFALEATADQSA 370

Query: 344  SSFEHEMSQEGFSAAITSNGPLLSTVGSYDWAGGVFLYTSKE-----KSTFINMTRVDSD 398
            +SFE EMSQ GFSA  + +  +L  VG+YDW G V +  + +      +TF   +   ++
Sbjct: 371  ASFEMEMSQTGFSAHYSQDWVMLGAVGAYDWNGTVVMQKASQIIIPRNTTFNVESTKKNE 430

Query: 399  MNDAYLGYAAAIILRNRVQSL-VLGAPRYQHIGLVAMFRQNTGMWESNANVKGTQIGAYF 457
               +YLGY       +    L + G PRY H G V ++R   G  +    + G QIG+YF
Sbjct: 431  PLASYLGYTVNSATASSGDVLYIAGQPRYNHTGQVIIYRMEDGNIKILQTLSGEQIGSYF 490

Query: 458  GASLCSVDVDSNGSTDLVLIGAPHYY--EQTRGGQVSVCPLPRGRARWQ----------C 505
            G+ L + D+D + +TD++L+GAP Y   E+   G+V V  L + R  +Q          C
Sbjct: 491  GSILTTTDIDKDSNTDILLVGAPMYMGTEKEEQGKVYVYALNQTRFEYQMSLEPIKQTCC 550

Query: 506  DAVLYG-----EQGQPWG-RFGAALTVLGDVNGDKLTDVAIGAPGEEDNRGAVYLFHGTS 559
             +  +       + +P G RFG A+  + D+N D   D+ IGAP E+D+ GAVY++HG S
Sbjct: 551  SSRQHNSCTTENKNEPCGARFGTAIAAVKDLNLDGFNDIVIGAPLEDDHGGAVYIYHG-S 609

Query: 560  GSGISPSHSQRIAGSKLSPRLQYFGQSLSGGQDLTMDGLVDLTVGAQGHVLLLRSQPVLR 619
            G  I   ++QRI        L++FGQS+ G  DL  DGL D+T+G  G   L  S+ V  
Sbjct: 610  GKTIRKEYAQRIPSGGDGKTLKFFGQSIHGEMDLNGDGLTDVTIGGLGGAALFWSRDVAV 669

Query: 620  VKAIMEFNPREVARNVFECNDQVVKGKEAG--EVRVCLHVQ-KSTRDRLREGQIQSVVTY 676
            VK  M F P +V      C+   ++GKE       VC  V+ KS  D + E  +Q    Y
Sbjct: 670  VKVTMNFEPNKVNIQKKNCH---MEGKETVCINATVCFDVKLKSKEDTIYEADLQ----Y 722

Query: 677  DLALDSGRPHSRAVFNET-KNSTRRQTQVLGLTQTCETLKLQLPNCIEDPVSPIVLRLNF 735
             + LDS R  SR+ F+ T +   +R   V     T  +  +   +  +D V    + L+F
Sbjct: 723  RVTLDSLRQISRSFFSGTQERKVQRNITVRKSECTKHSFYMLDKHDFQDSVR---ITLDF 779

Query: 736  SLVGTPLSAFGNLRPVLAEDAQRLFTALFPFEKNCGNDNICQDDLSITFSFMSLDCLVVG 795
            +L            PVL +          PF K+CGN   C  DLS+  +    D L+V 
Sbjct: 780  NLTDPENG------PVLDDSLPNSVHEYIPFAKDCGNKEKCISDLSLHVATTEKDLLIVR 833

Query: 796  GPRE-FNVTVTVRNDGEDSYRTQVTFFFPLDLSYRKVSTLQNQRSQRSWRLACESASSTE 854
               + FNV++TV+N  + +Y T+    +  +L +  +  +Q          +CES     
Sbjct: 834  SQNDKFNVSLTVKNTKDSAYNTRTIVHYSPNLVFSGIEAIQKD--------SCESN---- 881

Query: 855  VSGALKSTSCSINHPIFPENSEVTFNITFDVDSKASLGN-KLLLKANVTSENNMPRTNKT 913
                  + +C + +P       VTF I F  ++   + N  + L A   SE      +  
Sbjct: 882  -----HNITCKVGYPFLRRGEMVTFKILFQFNTSYLMENVTIYLSATSDSEEPPETLSDN 936

Query: 914  EFQLELPVKYAVYMVVTSHGVSTKYLNFTASENTSRVMQHQYQVSN-------------L 960
               + +PVKY V +   S   S  +++  A+E    V+     + N              
Sbjct: 937  VVNISIPVKYEVGLQFYS-SASEYHISIAANETVPEVINSTEDIGNEINIFYLIRKSGSF 995

Query: 961  GQRSLPISLVFLVPVRLNQTVIWDRPQVTFSENLSSTCHTKE---------RLPSHSDFL 1011
                L +S+ F         V++    ++ SEN +   H  E         ++ + +D  
Sbjct: 996  PMPELKLSISFPNMTSNGYPVLYP-TGLSSSENANCRPHIFEDPFSINSGKKMTTSTD-- 1052

Query: 1012 AELRKAPVVNCSIAVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYIKTSHNHLLIVSTAE 1071
              L++  +++C+      I C++    I  + N +L   L    +IK+  + L +    E
Sbjct: 1053 -HLKRGTILDCNTCKFATITCNLTSSDI-SQVNVSL--ILWKPTFIKSYFSSLNLTIRGE 1108

Query: 1072 ILFNDSVFTLLPGQGAFVRSQTETKVEPFEVPNPLPL--IVGSSVGGLLLLALITAALYK 1129
            +   ++   L     +  + +   ++    +P  +PL  I+ S+  GLLLL L+  AL+K
Sbjct: 1109 LRSENASLVL---SSSNQKRELAIQISKDGLPGRVPLWVILLSAFAGLLLLMLLILALWK 1165

Query: 1130 LGFFKRQYKDMMSE 1143
            +GFFKR  K  M +
Sbjct: 1166 IGFFKRPLKKKMEK 1179


>gi|52485853 integrin, alpha 11 precursor [Homo sapiens]
          Length = 1188

 Score =  380 bits (977), Expect = e-105
 Identities = 340/1196 (28%), Positives = 540/1196 (45%), Gaps = 126/1196 (10%)

Query: 17   FNLDTENAMTFQENARGFGQSVVQ---LQGSR-VVVGAPQEIVAANQRGSLYQCDYSTGS 72
            FN+DT        +   F    VQ   + G++ +VVGAP E     + G +Y+C    G+
Sbjct: 23   FNMDTRKPRVIPGSRTAFFGYTVQQHDISGNKWLVVGAPLETNGYQKTGDVYKCPVIHGN 82

Query: 73   CEPIRL------QVPVEAVNMSLGLSLAATTSPPQLLACGPTVHQTCSENTYVKGLCFLF 126
            C  + L       V     NM LGLSLA        LAC P     C  + Y  G+C   
Sbjct: 83   CTKLNLGRVTLSNVSERKDNMRLGLSLATNPKDNSFLACSPLWSHECGSSYYTTGMCSRV 142

Query: 127  GSNLRQQPQKFPEALRGCPQEDSDIAFLIDGSGSIIPHDFRRMKEFVSTVMEQ--LKKSK 184
             SN R      P AL+ C Q   DI  ++DGS SI P  +  ++ F+  ++++  +   +
Sbjct: 143  NSNFRFSKTVAP-ALQRC-QTYMDIVIVLDGSNSIYP--WVEVQHFLINILKKFYIGPGQ 198

Query: 185  TLFSLMQYSEEFRIHFTFKEFQNNPNPRSLVKPITQLLG-RTHTATGIRKVVRELFNITN 243
                ++QY E+    F   ++++  +       I Q  G  T TA GI     E F    
Sbjct: 199  IQVGVVQYGEDVVHEFHLNDYRSVKDVVEAASHIEQRGGTETRTAFGIEFARSEAFQ--K 256

Query: 244  GARKNAFKILVVITDGEKFGDPLGYEDVIPEADREGVIRYVIGVGDAFRS-----EKSRQ 298
            G RK A K+++VITDGE    P   E VI +++R+ V RY + V   +       E    
Sbjct: 257  GGRKGAKKVMIVITDGESHDSP-DLEKVIQQSERDNVTRYAVAVLGYYNRRGINPETFLN 315

Query: 299  ELNTIASKPPRDHVFQVNNFEALKTIQNQLREKIFAIEGTQTGSSSSFEHEMSQEGFSAA 358
            E+  IAS P   H F V +  ALK I + L ++IF++EGT   + +SF  EMSQ GFS+ 
Sbjct: 316  EIKYIASDPDDKHFFNVTDEAALKDIVDALGDRIFSLEGTNK-NETSFGLEMSQTGFSSH 374

Query: 359  ITSNGPLLSTVGSYDWAGGVFLYTSKEK-----STFINMTRVDSDMNDAYLGYAAAIILR 413
            +  +G LL  VG+YDW G V   TS  K      +++     +   + AYLGY    ++ 
Sbjct: 375  VVEDGVLLGAVGAYDWNGAVLKETSAGKVIPLRESYLKEFPEELKNHGAYLGYTVTSVVS 434

Query: 414  NRVQSL-VLGAPRYQHIGLVAMFRQ-NTGMWESNANVKGTQIGAYFGASLCSVDVDSNGS 471
            +R   + V GAPR+ H G V +F   N      +  ++G QIG+YFG+ + SVD+D +G 
Sbjct: 435  SRQGRVYVAGAPRFNHTGKVILFTMHNNRSLTIHQAMRGQQIGSYFGSEITSVDIDGDGV 494

Query: 472  TDLVLIGAPHYYEQTRG-GQVSVCPLPRGRARWQCDAVLYGEQGQPWGRFGAALTVLGDV 530
            TD++L+GAP Y+ + R  G+V V  L +    +  +  L         RFG+++  + D+
Sbjct: 495  TDVLLVGAPMYFNEGRERGKVYVYELRQNLFVY--NGTLKDSHSYQNARFGSSIASVRDL 552

Query: 531  NGDKLTDVAIGAPGEEDNRGAVYLFHGTSGSGISPSHSQRIAGSKLSPRLQYFGQSLSGG 590
            N D   DV +GAP E+++ GA+Y+FHG  GS I  +  QRI  S+L+  LQYFG S+ G 
Sbjct: 553  NQDSYNDVVVGAPLEDNHAGAIYIFHGFRGS-ILKTPKQRITASELATGLQYFGCSIHGQ 611

Query: 591  QDLTMDGLVDLTVGAQGHVLLLRSQPVLRVKAIMEFNPREVARNVF--ECNDQVVKGKEA 648
             DL  DGL+DL VGA G+ ++L S+PV+++ A + F P ++  N+F  +C       K +
Sbjct: 612  LDLNEDGLIDLAVGALGNAVILWSRPVVQINASLHFEPSKI--NIFHRDC-------KRS 662

Query: 649  GEVRVCLHVQKSTRDRLREGQIQSV---VTYDLALDSGRPHSRAVFNETKNS-TRRQTQV 704
            G    CL               Q+    + Y+  +D  R   RA  +E  +  T R   +
Sbjct: 663  GRDATCLAAFLCFTPIFLAPHFQTTTVGIRYNATMDERRYTPRAHLDEGGDRFTNRAVLL 722

Query: 705  LGLTQTCETLKLQLPNCIEDPVSPIVLRLNFSLVGTPLSAFGNLRPVLAEDAQRLFTALF 764
                + CE +   + +   D V P+   + +SL         +  P+L +          
Sbjct: 723  SSGQELCERINFHVLD-TADYVKPVTFSVEYSLEDP------DHGPMLDDGWPTTLRVSV 775

Query: 765  PFEKNCGNDNICQDDL---------------------------SITFSFMSLDCLVVGGP 797
            PF   C  D  C  DL                           + T SF +   ++    
Sbjct: 776  PFWNGCNEDEHCVPDLVLDARSDLPTAMEYCQRVLRKPAQDCSAYTLSFDTTVFIIESTR 835

Query: 798  REFNVTVTVRNDGEDSYRTQVTFFFPLDLSYRKVSTLQNQRSQRSWRLACESASSTEVSG 857
            +   V  T+ N GE++Y T +      +L +   S +Q + S  S     E         
Sbjct: 836  QRVAVEATLENRGENAYSTVLNISQSANLQF--ASLIQKEDSDGSIECVNEER------- 886

Query: 858  ALKSTSCSINHPIFPENSEVTFNITFDVDSKASLGNKLLLKANVTSENNMPRTNKTE--F 915
             L+   C++++P F   ++V F + F+  SK+   + L ++    S++N   + K +   
Sbjct: 887  RLQKQVCNVSYPFFRAKAKVAFRLDFEF-SKSIFLHHLEIELAAGSDSNERDSTKEDNVA 945

Query: 916  QLELPVKYAVYMVVTSHGVSTKYLNFTASENTSRVMQHQ--------YQVSNLGQ---RS 964
             L   +KY   ++ T    S+   ++    N+S              +++ NLG      
Sbjct: 946  PLRFHLKYEADVLFTR---SSSLSHYEVKPNSSLERYDGIGPPFSCIFRIQNLGLFPIHG 1002

Query: 965  LPISLVFLVPVRLNQTVIWDRPQVTFSENLSSTCHTKERLPSHSDFLAELRKAPVVNCSI 1024
            + + +   +  R    ++  R  +T   N S            +    +LR+AP +N S 
Sbjct: 1003 MMMKITIPIATRSGNRLLKLRDFLTDEANTSCNIWGNSTEYRPTPVEEDLRRAPQLNHSN 1062

Query: 1025 AVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYIKTSHNHLLIVSTAEILFNDSVFTLLPG 1084
            +    I C+I      +E N  L GNL   W         L   + +I+ N ++      
Sbjct: 1063 SDVVSINCNIRLVP-NQEINFHLLGNL---WLRSLK---ALKYKSMKIMVNAALQRQFHS 1115

Query: 1085 QGAFVRSQTETKVEPFEVPN------PLPLIVGSSVGGLLLLALITAALYKLGFFK 1134
               F R +  ++   FE+        P+ +IVGS++GGLLLLAL+  AL+KLGFF+
Sbjct: 1116 PFIF-REEDPSRQIVFEISKQEDWQVPIWIIVGSTLGGLLLLALLVLALWKLGFFR 1170


>gi|38569398 integrin, alpha 10 precursor [Homo sapiens]
          Length = 1167

 Score =  380 bits (977), Expect = e-105
 Identities = 345/1173 (29%), Positives = 551/1173 (46%), Gaps = 93/1173 (7%)

Query: 13   LCHGFNLDTENAMTFQENARG-FGQSVVQLQGSR---VVVGAPQEIVAANQRGSLYQC-- 66
            LC  FNLD  +   F       FG SV+Q  G     ++VGAP +  + ++RG +Y+C  
Sbjct: 19   LCSPFNLDEHHPRLFPGPPEAEFGYSVLQHVGGGQRWMLVGAPWDGPSGDRRGDVYRCPV 78

Query: 67   --------------DYSTGSCEPIRLQVPVEAVNMSLGLSLAATTSPPQLLACGPTVHQT 112
                          DY  G+           AVNM LG+SL  T      +AC P   + 
Sbjct: 79   GGAHNAPCAKGHLGDYQLGNSSH-------PAVNMHLGMSLLETDGDGGFMACAPLWSRA 131

Query: 113  CSENTYVKGLCFLFGSNLRQQPQKFPEALRGCPQEDSDIAFLIDGSGSIIPHDFRRMKEF 172
            C  + +  G+C    ++ + Q    P A R CP    D+  ++DGS SI P  +  ++ F
Sbjct: 132  CGSSVFSSGICARVDASFQPQGSLAPTAQR-CPTY-MDVVIVLDGSNSIYP--WSEVQTF 187

Query: 173  VSTVMEQL--KKSKTLFSLMQYSEEFRIHFTFKEFQNNPNPRSLVKPITQLLGR-THTAT 229
            +  ++ +L     +    L+QY E     ++  +F+         K +++  GR T TA 
Sbjct: 188  LRRLVGKLFIDPEQIQVGLVQYGESPVHEWSLGDFRTKEEVVRAAKNLSRREGRETKTAQ 247

Query: 230  GIRKVVRELFNITNGARKNAFKILVVITDGEKF-GDPLGYEDVIPEADREGVIRYVIGV- 287
             I     E F+ ++G R  A ++LVV+TDGE   G+ L       EA R  V RY I V 
Sbjct: 248  AIMVACTEGFSQSHGGRPEAARLLVVVTDGESHDGEELPAALKACEAGR--VTRYGIAVL 305

Query: 288  GDAFRSEKSR----QELNTIASKPPRDHVFQVNNFEALKTIQNQLREKIFAIEGTQTGSS 343
            G   R ++      +E+ TIAS P     F V +  AL  I + L ++IF +EG+   + 
Sbjct: 306  GHYLRRQRDPSSFLREIRTIASDPDERFFFNVTDEAALTDIVDALGDRIFGLEGSHAENE 365

Query: 344  SSFEHEMSQEGFSAAITSNGPLLSTVGSYDWAGGVFLYTSKEKSTFINMTRVDS-----D 398
            SSF  EMSQ GFS     +G L   VG+YDW G V       +     M   D       
Sbjct: 366  SSFGLEMSQIGFSTHRLKDGILFGMVGAYDWGGSVLWLEGGHRLFPPRMALEDEFPPALQ 425

Query: 399  MNDAYLGYA-AAIILRNRVQSLVLGAPRYQHIGLVAMFR-QNTGMWESNANVKGTQIGAY 456
             + AYLGY+ ++++LR   +  + GAPR++H G V  F+ +  G      +++G QIG+Y
Sbjct: 426  NHAAYLGYSVSSMLLRGGRRLFLSGAPRFRHRGKVIAFQLKKDGAVRVAQSLQGEQIGSY 485

Query: 457  FGASLCSVDVDSNGSTDLVLIGAPHYY--EQTRGGQVSVCPLPRGRARWQCDAVLYGEQG 514
            FG+ LC +D D +G+TD++L+ AP +   +    G+V V  L   ++       L  E  
Sbjct: 486  FGSELCPLDTDRDGTTDVLLVAAPMFLGPQNKETGRVYVY-LVGQQSLLTLQGTLQPEPP 544

Query: 515  QPWGRFGAALTVLGDVNGDKLTDVAIGAPGEEDNRGAVYLFHGTSGSGISPSHSQRIAGS 574
            Q   RFG A+  L D+N D   DVA+GAP E+ ++GA+YL+HGT  SG+ P  +QRIA +
Sbjct: 545  QD-ARFGFAMGALPDLNQDGFADVAVGAPLEDGHQGALYLYHGTQ-SGVRPHPAQRIAAA 602

Query: 575  KLSPRLQYFGQSLSGGQDLTMDGLVDLTVGAQGHVLLLRSQPVLRVKAIMEFNPREVARN 634
             +   L YFG+S+ G  DL  D LVD+ VGAQG  +LL S+P++ +   +E  P+ ++  
Sbjct: 603  SMPHALSYFGRSVDGRLDLDGDDLVDVAVGAQGAAILLSSRPIVHLTPSLEVTPQAISVV 662

Query: 635  VFECNDQVVKGKEAGEVRVCLHVQKSTRDRLREGQIQSVVTYDLALDSGRPHSRAVFNET 694
              +C     +G+EA  +   L  Q ++R   R    Q  + +  +LD     +RA F+ +
Sbjct: 663  QRDCRR---RGQEAVCLTAALCFQVTSRTPGRWDH-QFYMRFTASLDEWTAGARAAFDGS 718

Query: 695  --KNSTRRQTQVLGLTQTCETLKLQLPNCIEDPVSPIVLRLNFSLVGTPLSAFGNLRPVL 752
              + S RR    +G   TCE L   + +   D + P+ L + F+L  T         PVL
Sbjct: 719  GQRLSPRRLRLSVG-NVTCEQLHFHVLDT-SDYLRPVALTVTFALDNTTKPG-----PVL 771

Query: 753  AEDAQRLFTALFPFEKNCGNDNICQDDLSITFSF-----MSLDCLVVGGPREFNVTVTVR 807
             E +      L PF K+CG DN C  DL +  +           +V GG R+  V+ T+ 
Sbjct: 772  NEGSPTSIQKLVPFSKDCGPDNECVTDLVLQVNMDIRGSRKAPFVVRGGRRKVLVSTTLE 831

Query: 808  NDGEDSYRTQVTFFFPLDLSYRKVSTLQNQRSQRSWRLACESASSTEVSGALKSTSCSIN 867
            N  E++Y T ++  F  +L    +++L  QR +   ++ C + S+        +  CS+ 
Sbjct: 832  NRKENAYNTSLSLIFSRNLH---LASLTPQR-ESPIKVECAAPSA-------HARLCSVG 880

Query: 868  HPIFPENSEVTFNITFDVDSKASLGNKLLLKANVTS---ENNMPRTNKTEFQLELPVKYA 924
            HP+F   ++VTF + F+  S +SL +++ +K   +S   E N    + T  Q    ++Y 
Sbjct: 881  HPVFQTGAKVTFLLEFEF-SCSSLLSQVFVKLTASSDSLERNGTLQDNTA-QTSAYIQYE 938

Query: 925  VYMVVTSHGVSTKYLNF---TASENTSRVMQHQYQVSNLGQRSLP-ISLVFLVPVRLNQT 980
             +++ +S     +Y      T         +   +V NLG   +  + +  L+P   +  
Sbjct: 939  PHLLFSSESTLHRYEVHPYGTLPVGPGPEFKTTLRVQNLGCYVVSGLIISALLPAVAHGG 998

Query: 981  VIWDRPQVTFSENLSSTCHTKERLPSHSDFLAELRKAPVVNCSIAVCQRIQCDIPFFGIQ 1040
              +       + N S         P       EL+    +N S   CQ ++C +      
Sbjct: 999  NYFLSLSQVITNNASCIVQNLTEPPGPPVHPEELQHTNRLNGSNTQCQVVRCHLGQLAKG 1058

Query: 1041 EEFNATLKGNLSFDWYIKTSHNHLLIVSTAEILFNDSVFTLLPGQGAFVRSQTETKVEPF 1100
             E +  L   +  +++ +     L +VST E+   +     L     +  S  E  V+  
Sbjct: 1059 TEVSVGLLRLVHNEFFRRAKFKSLTVVSTFELGTEEGSVLQLTEASRWSESLLEV-VQTR 1117

Query: 1101 EVPNPLPLIVGSSVGGLLLLALITAALYKLGFF 1133
             +   L +++GS +GGLLLLAL+   L+KLGFF
Sbjct: 1118 PILISLWILIGSVLGGLLLLALLVFCLWKLGFF 1150


>gi|116295258 integrin alpha 2 precursor [Homo sapiens]
          Length = 1181

 Score =  373 bits (957), Expect = e-103
 Identities = 334/1200 (27%), Positives = 541/1200 (45%), Gaps = 127/1200 (10%)

Query: 11   LTLCHGFNLDTENAMTFQ-ENARGFGQSVVQL---QGSRVVVGAPQEIVAANQRGSLYQC 66
            L  C  +N+    A  F   ++  FG +V Q    +G+ ++VG+P      N+ G +Y+C
Sbjct: 24   LNCCLAYNVGLPEAKIFSGPSSEQFGYAVQQFINPKGNWLLVGSPWSGFPENRMGDVYKC 83

Query: 67   --DYSTGSCEPIRLQVPVEA-------VNMSLGLSLAATTSPPQLLACGPTVHQTCSENT 117
              D ST +CE + LQ             NMSLGL L         L CGP   Q C    
Sbjct: 84   PVDLSTATCEKLNLQTSTSIPNVTEMKTNMSLGLILTRNMGTGGFLTCGPLWAQQCGNQY 143

Query: 118  YVKGLCFLFGSNLRQQPQKFPEALRGCPQEDSDIAFLIDGSGSIIPHDFRRMKEFVSTVM 177
            Y  G+C     +  Q    F  A + CP    D+  + D S SI P D   +K F+   +
Sbjct: 144  YTTGVCSDISPDF-QLSASFSPATQPCPSL-IDVVVVCDESNSIYPWD--AVKNFLEKFV 199

Query: 178  EQLK--KSKTLFSLMQYSEEFRIHFTFKEFQNNPNPRSLVKPITQLLGR-THTATGIRKV 234
            + L    +KT   L+QY+   R+ F    ++            +Q  G  T+T   I+  
Sbjct: 200  QGLDIGPTKTQVGLIQYANNPRVVFNLNTYKTKEEMIVATSQTSQYGGDLTNTFGAIQYA 259

Query: 235  VRELFNITNGARKNAFKILVVITDGEKFGDPLGYEDVIPEADREGVIRYVIGV-----GD 289
             +  ++  +G R++A K++VV+TDGE     +  + VI + + + ++R+ I V      +
Sbjct: 260  RKYAYSAASGGRRSATKVMVVVTDGESHDGSM-LKAVIDQCNHDNILRFGIAVLGYLNRN 318

Query: 290  AFRSEKSRQELNTIASKPPRDHVFQVNNFEALKTIQNQLREKIFAIEGTQTGSSSSFEHE 349
            A  ++   +E+  IAS P   + F V++  AL      L E+IF+IEGT  G  + F+ E
Sbjct: 319  ALDTKNLIKEIKAIASIPTERYFFNVSDEAALLEKAGTLGEQIFSIEGTVQGGDN-FQME 377

Query: 350  MSQEGFSAAITSNGPLL--STVGSYDWAGGVFLYTSKEKSTFINMT--RVDSDMN-DAYL 404
            MSQ GFSA  +S   +L    VG++ W+G +   TS     F      ++  D N  +YL
Sbjct: 378  MSQVGFSADYSSQNDILMLGAVGAFGWSGTIVQKTSHGHLIFPKQAFDQILQDRNHSSYL 437

Query: 405  GYAAAIILRNRVQSLVLGAPRYQHIGLVAMFRQNTGMWESNANV------KGTQIGAYFG 458
            GY+ A I        V GAPR  + G + ++  N      N N+      +G QIG+YFG
Sbjct: 438  GYSVAAISTGESTHFVAGAPRANYTGQIVLYSVN-----ENGNITVIQAHRGDQIGSYFG 492

Query: 459  ASLCSVDVDSNGSTDLVLIGAPHYYEQTRG--GQVSVCPLPRGRARWQCDAVLYGEQGQP 516
            + LCSVDVD +  TD++L+GAP Y    +   G+V +  +  G         L G +G  
Sbjct: 493  SVLCSVDVDKDTITDVLLVGAPMYMSDLKKEEGRVYLFTIKEGILGQH--QFLEGPEGIE 550

Query: 517  WGRFGAALTVLGDVNGDKLTDVAIGAPGEEDNRGAVYLFHGTSGSGISPSHSQRIAGSKL 576
              RFG+A+  L D+N D   DV +G+P E  N GAVY+++G  G+ I   +SQ+I GS  
Sbjct: 551  NTRFGSAIAALSDINMDGFNDVIVGSPLENQNSGAVYIYNGHQGT-IRTKYSQKILGSDG 609

Query: 577  SPR--LQYFGQSLSGGQDLTMDGLVDLTVGAQGHVLLLRSQPVLRVKAIMEFNPREVARN 634
            + R  LQYFG+SL G  DL  D + D+++GA G V+ L SQ +  V     F P ++   
Sbjct: 610  AFRSHLQYFGRSLDGYGDLNGDSITDVSIGAFGQVVQLWSQSIADVAIEASFTPEKIT-- 667

Query: 635  VFECNDQVVKGKEAGEVRVCLHVQKSTRDRLREGQIQSVVTYDLALD----SGRPHSRAV 690
            +   N Q++       +++C     S + R  +   Q  + Y++ LD    S R  SR +
Sbjct: 668  LVNKNAQII-------LKLCF----SAKFRPTKQNNQVAIVYNITLDADGFSSRVTSRGL 716

Query: 691  FNETKNSTRRQTQVLGLTQTC--ETLKLQLPNCIEDPVSPIVLRLNFSLVGTPLSAFGNL 748
            F E      ++  V+   Q+C    + +Q P+   D V+ + LR++ SL     S     
Sbjct: 717  FKENNERCLQKNMVVNQAQSCPEHIIYIQEPS---DVVNSLDLRVDISLENPGTS----- 768

Query: 749  RPVLAEDAQRLFTALFPFEKNCGNDNICQDDLSITF----SFMSLDCLVVGGPREFNVTV 804
             P L   ++       PF K+CG D +C  DL +      +      +V    +    +V
Sbjct: 769  -PALEAYSETAKVFSIPFHKDCGEDGLCISDLVLDVRQIPAAQEQPFIVSNQNKRLTFSV 827

Query: 805  TVRNDGEDSYRTQVTFFFPLDLSYRKVSTLQNQRSQRSWRLACESASST-EVSGALKSTS 863
            T++N  E +Y T +   F  +L +             S+ L  +    T +V+ + KS +
Sbjct: 828  TLKNKRESAYNTGIVVDFSENLFFA------------SFSLPVDGTEVTCQVAASQKSVA 875

Query: 864  CSINHPIFPENSEVTFNITFDVDSKASLGNKLLLKANVTSENNMPRTNKTEFQLELPVKY 923
            C + +P      +VTF I FD + + +L N+  L     SE+           L++P+ Y
Sbjct: 876  CDVGYPALKREQQVTFTINFDFNLQ-NLQNQASLSFQALSESQEENKADNLVNLKIPLLY 934

Query: 924  AVYMVVTSHGVSTKYLNFTASENTSRVMQHQYQVSNLGQR---SLPISLVFLVPVRLNQT 980
               +    H   +  +NF    +   V    +   ++G +   SL ++    VPV +  T
Sbjct: 935  DAEI----HLTRSTNINFYEISSDGNVPSIVHSFEDVGPKFIFSLKVT-TGSVPVSM-AT 988

Query: 981  VIWDRPQVTFSENL-------------SSTCHTK------ERLPSHSDFLAE-LRKAPVV 1020
            VI   PQ T  +N                +C+         +  S   F +E  R    +
Sbjct: 989  VIIHIPQYTKEKNPLMYLTGVQTDKAGDISCNADINPLKIGQTSSSVSFKSENFRHTKEL 1048

Query: 1021 NCSIAVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYIKTSHNHLLIVSTAEILFNDSVFT 1080
            NC  A C  + C +    ++ E+   +   +    +  ++   + + + AEI   +    
Sbjct: 1049 NCRTASCSNVTCWLKDVHMKGEYFVNVTTRIWNGTFASSTFQTVQLTAAAEINTYNPEIY 1108

Query: 1081 LLPGQGAFVRSQTETKVEPFEVPNPLPLIVGSSVGGLLLLALITAALYKLGFFKRQYKDM 1140
            ++      +        E  EVP  +  I+GS + G+LLL  + A L+KLGFFKR+Y+ M
Sbjct: 1109 VIEDNTVTIPLMIMKPDEKAEVPTGV--IIGSIIAGILLLLALVAILWKLGFFKRKYEKM 1166


>gi|52485941 integrin, alpha 9 precursor [Homo sapiens]
          Length = 1035

 Score =  213 bits (541), Expect = 1e-54
 Identities = 228/860 (26%), Positives = 386/860 (44%), Gaps = 99/860 (11%)

Query: 347  EHEMSQEGFSAAITSNGPLLSTVGSYDWAGGVFLYTSKEKSTFINMTRVDSDMNDAYLGY 406
            EH   Q G +   T    ++   GS+ WAG + +    + +       V  +    YLGY
Sbjct: 190  EHGSCQAGIAGFFTEELVVMGAPGSFYWAGTIKVLNLTDNTYLKLNDEVIMNRRYTYLGY 249

Query: 407  A--AAIILRNRVQSLVLGAPRYQHIGLVAMFR--QNTGMWESNANVKGTQIGAYFGASLC 462
            A  A          +V GAP+ + IG V +FR  + +G         G ++G+YFG+SLC
Sbjct: 250  AVTAGHFSHPSTIDVVGGAPQDKGIGKVYIFRADRRSGTLIKIFQASGKKMGSYFGSSLC 309

Query: 463  SVDVDSNGSTDLVLIGAPHYYEQTRGGQVSVCPLPRGRARWQCDAVLYGEQGQPWGRFGA 522
            +VD++ +G +DL L+GAP + E    GQV+V  + RG    +    L G+ G     FG 
Sbjct: 310  AVDLNGDGLSDL-LVGAPMFSEIRDEGQVTVY-INRGNGALEEQLALTGD-GAYNAHFGE 366

Query: 523  ALTVLGDVNGDKLTDVAIGAPGEEDNRGAVYLFHGTSGSGISPSHSQRIAGSKLSPRLQY 582
            ++  L D++ D   DVAIGAP E+D  GAVY++HG +G GI P +S +++G K++P L+ 
Sbjct: 367  SIASLDDLDNDGFPDVAIGAPKEDDFAGAVYIYHGDAG-GIVPQYSMKLSGQKINPVLRM 425

Query: 583  FGQSLSGGQDLTMDGLVDLTVGA--QGHVLLLRSQPVLRVKAIMEFNPREVARNVFECND 640
            FGQS+SGG D+  +G  D+TVGA     V+LLR++PV+ V  +  F P  +     +C+D
Sbjct: 426  FGQSISGGIDMDGNGYPDVTVGAFMSDSVVLLRARPVITVD-VSIFLPGSINITAPQCHD 484

Query: 641  QVVKGKEAGEVRV-CLHVQK--STRDRLREGQI--QSVVTYDLALDSGRPHSRAVF---N 692
                    G+  V CL+V    S   +   G+I    V+  D+A        R  F    
Sbjct: 485  --------GQQPVNCLNVTTCFSFHGKHVPGEIGLNYVLMADVAKKEKGQMPRVYFVLLG 536

Query: 693  ETKNSTRRQTQVLGLTQTCETLKLQLPNCIEDPVSPIVLRLNFSL----VGTPLSAFGNL 748
            ET      + Q+  + +TC      +   ++D +SPIV    +SL     G        L
Sbjct: 537  ETMGQVTEKLQLTYMEETCRHYVAHVKRRVQDVISPIVFEAAYSLSEHVTGEEERELPPL 596

Query: 749  RPVL-----AEDAQRLFTALFPFEKNCGNDNICQDDLSITFSFM--SLD----CLVVGGP 797
             PVL      + AQ+  T    FE+NC +++ C  DL +    +  S+D     L +G  
Sbjct: 597  TPVLRWKKGQKIAQKNQTV---FERNCRSED-CAADLQLQGKLLLSSMDEKTLYLALGAV 652

Query: 798  REFNVTVTVRNDGEDSYRTQVTFFFPLDLSYRKVSTLQNQRSQRSWRLACESASSTEVSG 857
            +  ++ +++ N G+D+Y   V+F    +L +       N   +    ++CE   S  +  
Sbjct: 653  KNISLNISISNLGDDAYDANVSFNVSRELFF------INMWQKEEMGISCELLESDFL-- 704

Query: 858  ALKSTSCSINHPIFPENSEVTFNITFDVDSKASLGNKLLLKANVTSEN-NMPRT---NKT 913
                  CS+  P     S+  F++ FD    +  G + +L   VT+++ N  R+   +  
Sbjct: 705  -----KCSVGFPFMRSKSKYEFSVIFDTSHLS--GEEEVLSFIVTAQSGNTERSESLHDN 757

Query: 914  EFQLELPVKYAVYMVVTS--------HGVSTKYLNFTASENTS---RVMQHQYQVSNLGQ 962
               L +P+ + V   +T         +G S    NF   ++     + +    QV N G 
Sbjct: 758  TLVLMVPLMHEVDTSITGIMSPTSFVYGESVDAANFIQLDDLECHFQPINITLQVYNTGP 817

Query: 963  RSLPISLVFL-VPVRLN-----------QTVIWDRPQVTFSENLSSTCHTKERLPSHSDF 1010
             +LP S V +  P RL+             V  ++   +F +N +     +E+       
Sbjct: 818  STLPGSSVSISFPNRLSSGGAEMFHVQEMVVGQEKGNCSFQKNPTPCIIPQEQENIFHTI 877

Query: 1011 LAELRKA--PVVNCSI--AVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYIKTSHNHLLI 1066
             A   K+   V++C      C    C+      +E     +   L+ +   K S + +  
Sbjct: 878  FAFFTKSGRKVLDCEKPGISCLTAHCNFSALAKEESRTIDIYMLLNTEILKKDSSSVIQF 937

Query: 1067 VSTAEILFNDSVFTLLPGQGAFVRSQTETKVEPFEVPNPLPLIVG-----SSVGGLLLLA 1121
            +S A++  + ++  +    G     +     E      P   +VG     S + G+L+  
Sbjct: 938  MSRAKVKVDPALRVVEIAHGN--PEEVTVVFEALHNLEPRGYVVGWIIAISLLVGILIFL 995

Query: 1122 LITAALYKLGFFKRQYKDMM 1141
            L+   L+K+GFF+R+YK+++
Sbjct: 996  LLAVLLWKMGFFRRRYKEII 1015


>gi|67191027 integrin alpha 4 precursor [Homo sapiens]
          Length = 1032

 Score =  212 bits (539), Expect = 2e-54
 Identities = 224/862 (25%), Positives = 366/862 (42%), Gaps = 115/862 (13%)

Query: 352  QEGFSAAITSNGPLLSTVGSYDWAGGVFLY---TSKEKSTFINMTRVDSDMNDAYLGYA- 407
            Q G S+  T +  ++   GS  W G +F+Y   T+K K+      +V      +YLGY+ 
Sbjct: 199  QAGISSFYTKDLIVMGAPGSSYWTGSLFVYNITTNKYKAFLDKQNQVKFG---SYLGYSV 255

Query: 408  -AAIILRNRVQSLVLGAPRYQHIGLVAMFRQNTGMWESNANVKGTQIGAYFGASLCSVDV 466
             A          +V GAP+++ IG   +F  +         +KG ++G+YFGAS+C+VD+
Sbjct: 256  GAGHFRSQHTTEVVGGAPQHEQIGKAYIFSIDEKELNILHEMKGKKLGSYFGASVCAVDL 315

Query: 467  DSNGSTDLVLIGAPHYYEQTRGGQVSV-CPLPRGRARWQCDAVLYGEQGQPWGRFGAALT 525
            +++G +DL L+GAP        G+V V      G      +  L G       RFG ++ 
Sbjct: 316  NADGFSDL-LVGAPMQSTIREEGRVFVYINSGSGAVMNAMETNLVGSDKYA-ARFGESIV 373

Query: 526  VLGDVNGDKLTDVAIGAPGEEDNRGAVYLFHGTSGSGISPSHSQRIAGSKLSPRLQYFGQ 585
             LGD++ D   DVAIGAP E+D +GA+Y+++G +  GIS + SQRI G ++S  L  FGQ
Sbjct: 374  NLGDIDNDGFEDVAIGAPQEDDLQGAIYIYNGRA-DGISSTFSQRIEGLQISKSLSMFGQ 432

Query: 586  SLSGGQDLTMDGLVDLTVGA--QGHVLLLRSQPVLRVKAIMEFNPREVARNVFECNDQVV 643
            S+SG  D   +G VD+ VGA      +LLR++PV+ V A +  +P  V R  F+C     
Sbjct: 433  SISGQIDADNNGYVDVAVGAFRSDSAVLLRTRPVVIVDASLS-HPESVNRTKFDC----- 486

Query: 644  KGKEAGEVRVCLHVQKSTRDRLREGQIQSVVTYDLALDSGR-----PHSRAVFNETKNST 698
               E G   VC+ +      + +E     V+ Y+++LD  R     P      N T +  
Sbjct: 487  --VENGWPSVCIDLTLCFSYKGKEVPGYIVLFYNMSLDVNRKAESPPRFYFSSNGTSDVI 544

Query: 699  RRQTQVLGLTQTCETLKLQLPNCIEDPVSPIVLRLNFSLVGTPLS-----AFGNLRPVLA 753
                QV      C T +  +   + D ++PI +   + L    +S      F  L+P+L 
Sbjct: 545  TGSIQVSSREANCRTHQAFMRKDVRDILTPIQIEAAYHLGPHVISKRSTEEFPPLQPILQ 604

Query: 754  EDAQR-LFTALFPFEKNCGNDNICQDDLSITFSFMSL------DCLVVGGPREFNVTVTV 806
            +  ++ +      F + C ++N C  DL ++     L        L VG  +   + V++
Sbjct: 605  QKKEKDIMKKTINFARFCAHEN-CSADLQVSAKIGFLKPHENKTYLAVGSMKTLMLNVSL 663

Query: 807  RNDGEDSYRTQVTFFFPLDLSYRKVSTLQNQRSQRSWRLACESASSTEVSGALKSTSCSI 866
             N G+D+Y T +    P+ L + K+  L+ +      ++ CE    T+ SG ++   CSI
Sbjct: 664  FNAGDDAYETTLHVKLPVGLYFIKILELEEK------QINCE---VTDNSGVVQ-LDCSI 713

Query: 867  NHPIFPENSEVTFNITFDVDSKASLGNKLLLKANVTSEN--NMPRTNKTEFQLELPVKYA 924
             +      S +  +   DV S +     L +  + T EN   M     +   + +P+KY 
Sbjct: 714  GYIYVDHLSRIDISFLLDVSSLSRAEEDLSITVHATCENEEEMDNLKHSRVTVAIPLKYE 773

Query: 925  VYMVVTSHGVSTKYLNFTASENTSRV-----MQHQYQVSNLGQRSLP-ISLVFLVPVRLN 978
            V + V      T ++  +  EN         M   + V N G    P +S+  +VP   +
Sbjct: 774  VKLTVHGFVNPTSFVYGSNDENEPETCMVEKMNLTFHVINTGNSMAPNVSVEIMVPNSFS 833

Query: 979  QTV-----IWDRPQVT---FSENLSSTCHTKERLPSHSDFLAELRKAPVVNCSIAVCQRI 1030
                    I D    T     EN    C  +++  +       +R     +  +  C  I
Sbjct: 834  PQTDKLFNILDVQTTTGECHFENYQRVCALEQQKSAMQTLKGIVRFLSKTDKRLLYC--I 891

Query: 1031 QCDIPFFGIQEEFNATLKGNLSFDWYIKTSHNHLLIVSTAEILFNDSVFTLLPGQGAFVR 1090
            + D         F     G        K +  H+ +     IL  D    L         
Sbjct: 892  KADPHCLNFLCNFGKMESG--------KEASVHIQLEGRPSILEMDETSAL--------- 934

Query: 1091 SQTETKVEPFEVPNP-----------------------------LPLIVGSSVGGLLLLA 1121
             + E +   F  PNP                             + +I  S + GL++L 
Sbjct: 935  -KFEIRATGFPEPNPRVIELNKDENVAHVLLEGLHHQRPKRYFTIVIISSSLLLGLIVLL 993

Query: 1122 LITAALYKLGFFKRQYKDMMSE 1143
            LI+  ++K GFFKRQYK ++ E
Sbjct: 994  LISYVMWKAGFFKRQYKSILQE 1015



 Score = 33.5 bits (75), Expect = 1.2
 Identities = 39/144 (27%), Positives = 59/144 (40%), Gaps = 14/144 (9%)

Query: 462 CSVDVDSNGSTDLVLIGAPHYYEQTRGGQVSVCPLPRGRARWQCDAVLYGEQGQPWGRFG 521
           C   + S  + DL+++GAP     T  G + V  +   + +    A L  +    +G + 
Sbjct: 198 CQAGISSFYTKDLIVMGAPGSSYWT--GSLFVYNITTNKYK----AFLDKQNQVKFGSYL 251

Query: 522 AALTVLGDVNGDKLTDVAIGAPGEEDNRGAVYLFHGTSGSGISPSHSQRIAGSKLSPRLQ 581
                 G       T+V  GAP + +  G  Y+F       ++  H  +  G KL     
Sbjct: 252 GYSVGAGHFRSQHTTEVVGGAP-QHEQIGKAYIF-SIDEKELNILHEMK--GKKLG---S 304

Query: 582 YFGQSLSGGQDLTMDGLVDLTVGA 605
           YFG S+    DL  DG  DL VGA
Sbjct: 305 YFGASVC-AVDLNADGFSDLLVGA 327



 Score = 32.7 bits (73), Expect = 2.0
 Identities = 44/159 (27%), Positives = 71/159 (44%), Gaps = 27/159 (16%)

Query: 5   VLLLTALTLCHG--FNLDTENAMTFQ-ENARGFGQSVV-QLQGSR--VVVGAPQEIVAAN 58
           V+LL  L +  G  +N+DTE+A+ +Q  +   FG SVV    G+   ++VGAP     AN
Sbjct: 20  VMLLLCLGVPTGRPYNVDTESALLYQGPHNTLFGYSVVLHSHGANRWLLVGAPTANWLAN 79

Query: 59  ----QRGSLYQCDYSTG---SCEPIRLQVP----------VEAVNMSLGLSLAATTSP-P 100
                 G++Y+C        +CE ++L  P           E  N  LG++L+       
Sbjct: 80  ASVINPGAIYRCRIGKNPGQTCEQLQLGSPNGEPCGKTCLEERDNQWLGVTLSRQPGENG 139

Query: 101 QLLACG---PTVHQTCSENTYVKGLCFLFGSNLRQQPQK 136
            ++ CG     +    +EN    G C+    +LR +  K
Sbjct: 140 SIVTCGHRWKNIFYIKNENKLPTGGCYGVPPDLRTELSK 178


>gi|223468595 integrin alpha-V isoform 2 [Homo sapiens]
          Length = 1002

 Score =  168 bits (426), Expect = 2e-41
 Identities = 204/861 (23%), Positives = 362/861 (42%), Gaps = 100/861 (11%)

Query: 352  QEGFSAAIT-SNGPLLSTVGSYDWAGGVF--------------LYTSKEKSTFINMTRVD 396
            Q GFS   T ++  LL   GS+ W G +               +Y+ K  +     T   
Sbjct: 140  QGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPNVYSIKYNNQLATRT-AQ 198

Query: 397  SDMNDAYLGYAAAI--ILRNRVQSLVLGAPRYQH-IGLVAMFRQNTGMWESNANVKGTQI 453
            +  +D+YLGY+ A+     + +   V G PR    +G+V ++        S  N  G Q+
Sbjct: 199  AIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKN--MSSLYNFTGEQM 256

Query: 454  GAYFGASLCSVDVDSNGSTDLVLIGAPHYYEQTRGG------QVSVCPLPRGRARWQCDA 507
             AYFG S+ + D++ +   D V IGAP + ++   G      QVSV  L R    +Q   
Sbjct: 257  AAYFGFSVAATDINGDDYAD-VFIGAPLFMDRGSDGKLQEVGQVSVS-LQRASGDFQTTK 314

Query: 508  VLYGEQGQPWGRFGAALTVLGDVNGDKLTDVAIGAP-GEEDNRGAVYLFHGTSGSGISPS 566
            +      + + RFG+A+  LGD++ D   D+AI AP G ED +G VY+F+G S +G++  
Sbjct: 315  L---NGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRS-TGLNAV 370

Query: 567  HSQRIAGSKLSPRL-QYFGQSLSGGQDLTMDGLVDLTVGAQG--HVLLLRSQPVLRVKAI 623
             SQ + G   +  +   FG S+ G  D+  +G  DL VGA G    +L R++PV+ V A 
Sbjct: 371  PSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAG 430

Query: 624  MEFNPREVARNVFECNDQVVKGK-EAGEVRVCLHVQ-KSTRDRLREGQIQSVVTYDLALD 681
            +E  P  + ++   C+      K     VR CL    K    R    Q++ ++   L   
Sbjct: 431  LEVYPSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLD-KLKQK 489

Query: 682  SGRPHSRAVFNETKNSTRRQTQVLGLTQTCETLKLQLPNCIE--DPVSPIVLRLNFSLVG 739
                 +  +++ + + ++  T   G    CE L   L +  E  D ++PI + + + L  
Sbjct: 490  GAIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEYRLDY 549

Query: 740  TPLSAFGNLRPVLAEDAQRLFTALFPFEKNCGNDNICQDDLSITFSFMSLDCLVVGGPRE 799
               +    L+P+L +      +       +CG DN+C+  L ++        + +G    
Sbjct: 550  RTAADTTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVD-SDQKKIYIGDDNP 608

Query: 800  FNVTVTVRNDGEDSYRTQVTFFFPLDLSYRKVSTLQNQRSQRSWRLACESASSTEVSGAL 859
              + V  +N GE +Y  ++    PL   +  +  ++N  +    RL+C  A  TE     
Sbjct: 609  LTLIVKAQNQGEGAYEAELIVSIPLQADF--IGVVRNNEALA--RLSC--AFKTE--NQT 660

Query: 860  KSTSCSINHPIFPENSEVTFNITFDVDSKASLGNKLLLKANVTSENNMPRTNKTEFQLEL 919
            +   C + +P+    +++   + F V  ++ +   +     + S N   + +     +  
Sbjct: 661  RQVVCDLGNPM-KAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPV---VSH 716

Query: 920  PVKYAVYMVVTSHGVSTK---YL---------NFTASENTSRVMQHQYQVSNLGQRSLPI 967
             V  AV   V   GVS+    +L         N    E+   V+QH Y++ N G  S   
Sbjct: 717  KVDLAVLAAVEIRGVSSPDHIFLPIPNWEHKENPETEEDVGPVVQHIYELRNNGPSSFSK 776

Query: 968  SLVFLV-PVRLNQTVIW-------DRP-------------------QVTFSENLSSTCHT 1000
            +++ L  P + N   +        D P                   Q T   +  +    
Sbjct: 777  AMLHLQWPYKYNNNTLLYILHYDIDGPMNCTSDMEINPLRIKISSLQTTEKNDTVAGQGE 836

Query: 1001 KERLPSHSDFLAELRKAPVVNCSIAVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYI-KT 1059
            ++ L +  D          + C +A C +I C +      +     +K  L  + ++ K 
Sbjct: 837  RDHLITKRDLALSEGDIHTLGCGVAQCLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKE 896

Query: 1060 SHNH-LLIVSTAEILFNDSVFTLLP----GQGAFVRSQTETKVEPFEVPNPLPLIVGSSV 1114
            + NH   + S+A     +  +  LP         V +     ++P  +P P+ +I+ + +
Sbjct: 897  NQNHSYSLKSSASFNVIEFPYKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVL 956

Query: 1115 GGLLLLALITAALYKLGFFKR 1135
             GLLLLA++   +Y++GFFKR
Sbjct: 957  AGLLLLAVLVFVMYRMGFFKR 977


>gi|4504763 integrin alpha-V isoform 1 precursor [Homo sapiens]
          Length = 1048

 Score =  168 bits (426), Expect = 2e-41
 Identities = 204/861 (23%), Positives = 362/861 (42%), Gaps = 100/861 (11%)

Query: 352  QEGFSAAIT-SNGPLLSTVGSYDWAGGVF--------------LYTSKEKSTFINMTRVD 396
            Q GFS   T ++  LL   GS+ W G +               +Y+ K  +     T   
Sbjct: 186  QGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPNVYSIKYNNQLATRT-AQ 244

Query: 397  SDMNDAYLGYAAAI--ILRNRVQSLVLGAPRYQH-IGLVAMFRQNTGMWESNANVKGTQI 453
            +  +D+YLGY+ A+     + +   V G PR    +G+V ++        S  N  G Q+
Sbjct: 245  AIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKN--MSSLYNFTGEQM 302

Query: 454  GAYFGASLCSVDVDSNGSTDLVLIGAPHYYEQTRGG------QVSVCPLPRGRARWQCDA 507
             AYFG S+ + D++ +   D V IGAP + ++   G      QVSV  L R    +Q   
Sbjct: 303  AAYFGFSVAATDINGDDYAD-VFIGAPLFMDRGSDGKLQEVGQVSVS-LQRASGDFQTTK 360

Query: 508  VLYGEQGQPWGRFGAALTVLGDVNGDKLTDVAIGAP-GEEDNRGAVYLFHGTSGSGISPS 566
            +      + + RFG+A+  LGD++ D   D+AI AP G ED +G VY+F+G S +G++  
Sbjct: 361  L---NGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRS-TGLNAV 416

Query: 567  HSQRIAGSKLSPRL-QYFGQSLSGGQDLTMDGLVDLTVGAQG--HVLLLRSQPVLRVKAI 623
             SQ + G   +  +   FG S+ G  D+  +G  DL VGA G    +L R++PV+ V A 
Sbjct: 417  PSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAG 476

Query: 624  MEFNPREVARNVFECNDQVVKGK-EAGEVRVCLHVQ-KSTRDRLREGQIQSVVTYDLALD 681
            +E  P  + ++   C+      K     VR CL    K    R    Q++ ++   L   
Sbjct: 477  LEVYPSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLD-KLKQK 535

Query: 682  SGRPHSRAVFNETKNSTRRQTQVLGLTQTCETLKLQLPNCIE--DPVSPIVLRLNFSLVG 739
                 +  +++ + + ++  T   G    CE L   L +  E  D ++PI + + + L  
Sbjct: 536  GAIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEYRLDY 595

Query: 740  TPLSAFGNLRPVLAEDAQRLFTALFPFEKNCGNDNICQDDLSITFSFMSLDCLVVGGPRE 799
               +    L+P+L +      +       +CG DN+C+  L ++        + +G    
Sbjct: 596  RTAADTTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVD-SDQKKIYIGDDNP 654

Query: 800  FNVTVTVRNDGEDSYRTQVTFFFPLDLSYRKVSTLQNQRSQRSWRLACESASSTEVSGAL 859
              + V  +N GE +Y  ++    PL   +  +  ++N  +    RL+C  A  TE     
Sbjct: 655  LTLIVKAQNQGEGAYEAELIVSIPLQADF--IGVVRNNEALA--RLSC--AFKTE--NQT 706

Query: 860  KSTSCSINHPIFPENSEVTFNITFDVDSKASLGNKLLLKANVTSENNMPRTNKTEFQLEL 919
            +   C + +P+    +++   + F V  ++ +   +     + S N   + +     +  
Sbjct: 707  RQVVCDLGNPM-KAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPV---VSH 762

Query: 920  PVKYAVYMVVTSHGVSTK---YL---------NFTASENTSRVMQHQYQVSNLGQRSLPI 967
             V  AV   V   GVS+    +L         N    E+   V+QH Y++ N G  S   
Sbjct: 763  KVDLAVLAAVEIRGVSSPDHIFLPIPNWEHKENPETEEDVGPVVQHIYELRNNGPSSFSK 822

Query: 968  SLVFLV-PVRLNQTVIW-------DRP-------------------QVTFSENLSSTCHT 1000
            +++ L  P + N   +        D P                   Q T   +  +    
Sbjct: 823  AMLHLQWPYKYNNNTLLYILHYDIDGPMNCTSDMEINPLRIKISSLQTTEKNDTVAGQGE 882

Query: 1001 KERLPSHSDFLAELRKAPVVNCSIAVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYI-KT 1059
            ++ L +  D          + C +A C +I C +      +     +K  L  + ++ K 
Sbjct: 883  RDHLITKRDLALSEGDIHTLGCGVAQCLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKE 942

Query: 1060 SHNH-LLIVSTAEILFNDSVFTLLP----GQGAFVRSQTETKVEPFEVPNPLPLIVGSSV 1114
            + NH   + S+A     +  +  LP         V +     ++P  +P P+ +I+ + +
Sbjct: 943  NQNHSYSLKSSASFNVIEFPYKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVL 1002

Query: 1115 GGLLLLALITAALYKLGFFKR 1135
             GLLLLA++   +Y++GFFKR
Sbjct: 1003 AGLLLLAVLVFVMYRMGFFKR 1023



 Score = 31.6 bits (70), Expect = 4.5
 Identities = 36/137 (26%), Positives = 54/137 (39%), Gaps = 23/137 (16%)

Query: 11  LTLCHGFNLDTENAMTFQ-ENARGFGQSV---VQLQGSR--VVVGAPQEIVAAN---QRG 61
           L LC  FNLD ++   +       FG +V   V    SR  ++VGAP+         + G
Sbjct: 25  LPLCRAFNLDVDSPAEYSGPEGSYFGFAVDFFVPSASSRMFLLVGAPKANTTQPGIVEGG 84

Query: 62  SLYQCDY-STGSCEPIRLQV----------PVEAVNMSLGLSLAATTSPPQLLACGPTVH 110
            + +CD+ ST  C+PI              P+E          +  +   ++LAC P  H
Sbjct: 85  QVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLE-FKSHQWFGASVRSKQDKILACAPLYH 143

Query: 111 --QTCSENTYVKGLCFL 125
                 +     G CFL
Sbjct: 144 WRTEMKQEREPVGTCFL 160


>gi|56237029 integrin alpha 5 precursor [Homo sapiens]
          Length = 1049

 Score =  168 bits (425), Expect = 3e-41
 Identities = 222/862 (25%), Positives = 366/862 (42%), Gaps = 117/862 (13%)

Query: 352  QEGFSAAITSNGPL-LSTVGSYDWAGGVFLYTSKEKST------FINMTR-------VDS 397
            Q GFSA  T  G + L   GSY W G +   T ++ +        IN+ +         S
Sbjct: 206  QGGFSAEFTKTGRVVLGGPGSYFWQGQILSATQEQIAESYYPEYLINLVQGQLQTRQASS 265

Query: 398  DMNDAYLGYAAAI--ILRNRVQSLVLGAPR----YQHIGLVAMFRQNTGMWESNANVKGT 451
              +D+YLGY+ A+     +  +  V G P+    Y ++ ++     N     S  N  G 
Sbjct: 266  IYDDSYLGYSVAVGEFSGDDTEDFVAGVPKGNLTYGYVTIL-----NGSDIRSLYNFSGE 320

Query: 452  QIGAYFGASLCSVDVDSNGSTDLVLIGAPHYYEQTRGGQVSVCPLPRGR--------ARW 503
            Q+ +YFG ++ + DV+ +G  DL L+GAP   ++T  G+    P   GR        A  
Sbjct: 321  QMASYFGYAVAATDVNGDGLDDL-LVGAPLLMDRTPDGR----PQEVGRVYVYLQHPAGI 375

Query: 504  QCDAVLYGEQGQPWGRFGAALTVLGDVNGDKLTDVAIGAP-GEEDNRGAVYLF-HGTSGS 561
            +    L       +GRFG++LT LGD++ D   DVAIGAP G E  +G V++F  G  G 
Sbjct: 376  EPTPTLTLTGHDEFGRFGSSLTPLGDLDQDGYNDVAIGAPFGGETQQGVVFVFPGGPGGL 435

Query: 562  GISPSH-SQRIAGSKLSPRLQYFGQSLSGGQDLTMDGLVDLTVGAQG--HVLLLRSQPVL 618
            G  PS   Q +  +  +P   +FG +L GG+DL  +G  DL VG+ G    ++ R +P++
Sbjct: 436  GSKPSQVLQPLWAASHTP--DFFGSALRGGRDLDGNGYPDLIVGSFGVDKAVVYRGRPIV 493

Query: 619  RVKAIME-----FNPREVARNVFECNDQVVKGKEAGEVRVCLHVQKSTRDRLREGQIQSV 673
               A +      FNP E + ++             G    C+++        +       
Sbjct: 494  SASASLTIFPAMFNPEERSCSL------------EGNPVACINLSFCLNASGKHVADSIG 541

Query: 674  VTYDLALDSGRPHS---RAVFNETKNSTRRQTQVL--GLTQTCETLKLQLPNCIE--DPV 726
             T +L LD  +      RA+F  ++ +T  QT ++  G  + C  +K+ L N  E  D +
Sbjct: 542  FTVELQLDWQKQKGGVRRALFLASRQATLTQTLLIQNGAREDCREMKIYLRNESEFRDKL 601

Query: 727  SPIVLRLNFSL-VGTPLSAFGNLRPVLAEDAQRLFTALFPFEKNCGNDNICQDDLSITFS 785
            SPI + LNFSL    P+ + G LRP L   ++           +CG DNIC  DL +   
Sbjct: 602  SPIHIALNFSLDPQAPVDSHG-LRPALHYQSKSRIEDKAQILLDCGEDNICVPDLQLEV- 659

Query: 786  FMSLDCLVVGGPREFNVTVTVRNDGE-DSYRTQVTFFFPLDLSYRKVSTLQNQRSQRSWR 844
            F   + + +G     N+T   +N GE  +Y  ++    P +  Y  +       S     
Sbjct: 660  FGEQNHVYLGDKNALNLTFHAQNVGEGGAYEAELRVTAPPEAEYSGLVRHPGNFSS---- 715

Query: 845  LACESASSTEVSGALKSTSCSINHPIFPENSEVTFNITFDVDSKASLGNKLLLKANVTSE 904
            L+C+  +  +     +   C + +P+    + +   + F V         +     + S+
Sbjct: 716  LSCDYFAVNQ----SRLLVCDLGNPM-KAGASLWGGLRFTVPHLRDTKKTIQFDFQILSK 770

Query: 905  N-NMPRTNKTEFQLELPVKYAVYMVVTSHGVS-TKYLNFTAS-----------ENTSRVM 951
            N N  +++   F+L +  +      VT +GVS  + + F  S           E+    +
Sbjct: 771  NLNNSQSDVVSFRLSVEAQ----AQVTLNGVSKPEAVLFPVSDWHPRDQPQKEEDLGPAV 826

Query: 952  QHQYQVSNLGQRSLPISLVFL-VPVRLNQTVIWDRPQVT---FSENLSSTCHTKERLPSH 1007
             H Y++ N G  S+   ++ L  P  L    +    +VT    + N        E  P  
Sbjct: 827  HHVYELINQGPSSISQGVLELSCPQALEGQQLLYVTRVTGLNCTTNHPINPKGLELDPEG 886

Query: 1008 SDFLAELRKAP----------VVNCSIAVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYI 1057
            S    + R+AP          ++ C  A C R++C++     QE  +  L   +    ++
Sbjct: 887  SLHHQQKREAPSRSSASSGPQILKCPEAECFRLRCELGPLHQQESQSLQLHFRVWAKTFL 946

Query: 1058 KTSHNHLLIVSTAEILFNDSVFTLLPGQGAFVRSQTETKVEPFEVPN----PLPLIVGSS 1113
            +  H    +   A        + +LP Q      Q  T V+  +       PL +I+ + 
Sbjct: 947  QREHQPFSLQCEAVYKALKMPYRILPRQLPQKERQVATAVQWTKAEGSYGVPLWIIILAI 1006

Query: 1114 VGGLLLLALITAALYKLGFFKR 1135
            + GLLLL L+   LYKLGFFKR
Sbjct: 1007 LFGLLLLGLLIYILYKLGFFKR 1028


>gi|223468597 integrin alpha-V isoform 3 precursor [Homo sapiens]
          Length = 1012

 Score =  164 bits (416), Expect = 3e-40
 Identities = 190/798 (23%), Positives = 340/798 (42%), Gaps = 84/798 (10%)

Query: 400  NDAYLGYAAAI--ILRNRVQSLVLGAPRYQH-IGLVAMFRQNTGMWESNANVKGTQIGAY 456
            +D+YLGY+ A+     + +   V G PR    +G+V ++        S  N  G Q+ AY
Sbjct: 212  DDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKN--MSSLYNFTGEQMAAY 269

Query: 457  FGASLCSVDVDSNGSTDLVLIGAPHYYEQTRGG------QVSVCPLPRGRARWQCDAVLY 510
            FG S+ + D++ +   D V IGAP + ++   G      QVSV  L R    +Q   +  
Sbjct: 270  FGFSVAATDINGDDYAD-VFIGAPLFMDRGSDGKLQEVGQVSVS-LQRASGDFQTTKL-- 325

Query: 511  GEQGQPWGRFGAALTVLGDVNGDKLTDVAIGAP-GEEDNRGAVYLFHGTSGSGISPSHSQ 569
                + + RFG+A+  LGD++ D   D+AI AP G ED +G VY+F+G S +G++   SQ
Sbjct: 326  -NGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRS-TGLNAVPSQ 383

Query: 570  RIAGSKLSPRL-QYFGQSLSGGQDLTMDGLVDLTVGAQG--HVLLLRSQPVLRVKAIMEF 626
             + G   +  +   FG S+ G  D+  +G  DL VGA G    +L R++PV+ V A +E 
Sbjct: 384  ILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAGLEV 443

Query: 627  NPREVARNVFECNDQVVKGK-EAGEVRVCLHVQ-KSTRDRLREGQIQSVVTYDLALDSGR 684
             P  + ++   C+      K     VR CL    K    R    Q++ ++   L      
Sbjct: 444  YPSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLD-KLKQKGAI 502

Query: 685  PHSRAVFNETKNSTRRQTQVLGLTQTCETLKLQLPNCIE--DPVSPIVLRLNFSLVGTPL 742
              +  +++ + + ++  T   G    CE L   L +  E  D ++PI + + + L     
Sbjct: 503  RRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEYRLDYRTA 562

Query: 743  SAFGNLRPVLAEDAQRLFTALFPFEKNCGNDNICQDDLSITFSFMSLDCLVVGGPREFNV 802
            +    L+P+L +      +       +CG DN+C+  L ++        + +G      +
Sbjct: 563  ADTTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVD-SDQKKIYIGDDNPLTL 621

Query: 803  TVTVRNDGEDSYRTQVTFFFPLDLSYRKVSTLQNQRSQRSWRLACESASSTEVSGALKST 862
             V  +N GE +Y  ++    PL   +  +  ++N  +    RL+C  A  TE     +  
Sbjct: 622  IVKAQNQGEGAYEAELIVSIPLQADF--IGVVRNNEALA--RLSC--AFKTE--NQTRQV 673

Query: 863  SCSINHPIFPENSEVTFNITFDVDSKASLGNKLLLKANVTSENNMPRTNKTEFQLELPVK 922
             C + +P+    +++   + F V  ++ +   +     + S N   + +     +   V 
Sbjct: 674  VCDLGNPM-KAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPV---VSHKVD 729

Query: 923  YAVYMVVTSHGVSTK---YL---------NFTASENTSRVMQHQYQVSNLGQRSLPISLV 970
             AV   V   GVS+    +L         N    E+   V+QH Y++ N G  S   +++
Sbjct: 730  LAVLAAVEIRGVSSPDHIFLPIPNWEHKENPETEEDVGPVVQHIYELRNNGPSSFSKAML 789

Query: 971  FLV-PVRLNQTVIW-------DRP-------------------QVTFSENLSSTCHTKER 1003
             L  P + N   +        D P                   Q T   +  +    ++ 
Sbjct: 790  HLQWPYKYNNNTLLYILHYDIDGPMNCTSDMEINPLRIKISSLQTTEKNDTVAGQGERDH 849

Query: 1004 LPSHSDFLAELRKAPVVNCSIAVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYI-KTSHN 1062
            L +  D          + C +A C +I C +      +     +K  L  + ++ K + N
Sbjct: 850  LITKRDLALSEGDIHTLGCGVAQCLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKENQN 909

Query: 1063 H-LLIVSTAEILFNDSVFTLLP----GQGAFVRSQTETKVEPFEVPNPLPLIVGSSVGGL 1117
            H   + S+A     +  +  LP         V +     ++P  +P P+ +I+ + + GL
Sbjct: 910  HSYSLKSSASFNVIEFPYKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAGL 969

Query: 1118 LLLALITAALYKLGFFKR 1135
            LLLA++   +Y++GFFKR
Sbjct: 970  LLLAVLVFVMYRMGFFKR 987



 Score = 31.6 bits (70), Expect = 4.5
 Identities = 36/137 (26%), Positives = 54/137 (39%), Gaps = 23/137 (16%)

Query: 11  LTLCHGFNLDTENAMTFQ-ENARGFGQSV---VQLQGSR--VVVGAPQEIVAAN---QRG 61
           L LC  FNLD ++   +       FG +V   V    SR  ++VGAP+         + G
Sbjct: 25  LPLCRAFNLDVDSPAEYSGPEGSYFGFAVDFFVPSASSRMFLLVGAPKANTTQPGIVEGG 84

Query: 62  SLYQCDY-STGSCEPIRLQV----------PVEAVNMSLGLSLAATTSPPQLLACGPTVH 110
            + +CD+ ST  C+PI              P+E          +  +   ++LAC P  H
Sbjct: 85  QVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLE-FKSHQWFGASVRSKQDKILACAPLYH 143

Query: 111 --QTCSENTYVKGLCFL 125
                 +     G CFL
Sbjct: 144 WRTEMKQEREPVGTCFL 160


>gi|4504747 integrin alpha 3 isoform a precursor [Homo sapiens]
          Length = 1051

 Score =  164 bits (414), Expect = 6e-40
 Identities = 210/871 (24%), Positives = 365/871 (41%), Gaps = 124/871 (14%)

Query: 347  EHEMSQEGFSAAITSNGPLLSTVGSYDWAGGVFLYTSKEKSTFINMTRVDSDMNDAYLGY 406
            E  M Q G S   T N       G+Y+W G  ++   KE        +   D  + Y+GY
Sbjct: 193  ETGMCQLGTSGGFTQNTVYFGAPGAYNWKGNSYMIQRKEWDLSEYSYKDPEDQGNLYIGY 252

Query: 407  AAAI---ILRNRVQSLVLGAPRYQHIGLVAMFRQNTGMWESNANV-KGTQIGAYFGASLC 462
               +   IL  +  ++V GAPR++H+G V +  Q  G       V +G+Q+GAYFG+++ 
Sbjct: 253  TMQVGSFILHPKNITIVTGAPRHRHMGAVFLLSQEAGGDLRRRQVLEGSQVGAYFGSAIA 312

Query: 463  SVDVDSNGSTDLVLIGAPHYYEQTR--GGQVSVCPLPRGRA-RWQCDAVLYGEQGQPWGR 519
              D++++G  DL L+GAP+Y+E+    GG + V     G +       +L+G  G     
Sbjct: 313  LADLNNDGWQDL-LVGAPYYFERKEEVGGAIYVFMNQAGTSFPAHPSLLLHGPSG---SA 368

Query: 520  FGAALTVLGDVNGDKLTDVAIGAPGEEDNRGAVYLFHGTSGSGISPSHSQRIAGSKLS-P 578
            FG ++  +GD+N D   D+A+GAP E    G VY++H +S  G+     Q I G KL  P
Sbjct: 369  FGLSVASIGDINQDGFQDIAVGAPFE--GLGKVYIYH-SSSKGLLRQPQQVIHGEKLGLP 425

Query: 579  RLQYFGQSLSGGQDLTMDGLVDLTVGA-QGHVLLLRSQPVLRV--KAIMEFNPREVARNV 635
             L  FG SLSG  D+  +   DL VG+   H++LLR++PV+ +  K ++   PR    + 
Sbjct: 426  GLATFGYSLSGQMDVDENFYPDLLVGSLSDHIVLLRARPVINIVHKTLV---PRPAVLDP 482

Query: 636  FECNDQVVKGKEAGEVRVCLHVQKSTRDRLREGQIQSVVTYDLALDSGRPHSRAVFNETK 695
              C           +V +C    +S  +      I   + Y L  D  R   R  F  ++
Sbjct: 483  ALCT-----ATSCVQVELCFAYNQSAGNPNYRRNI--TLAYTLEADRDRRPPRLRFAGSE 535

Query: 696  NSTRRQTQVLGLTQTCETLKLQLPNCIEDPVSPIVLRLNFSL-VGTPLSAFGNLR----- 749
            ++       +     C+ L+L L + + D + PI++ +N+SL +  P      LR     
Sbjct: 536  SAVFHGFFSMP-EMRCQKLELLLMDNLRDKLRPIIISMNYSLPLRMPDRPRLGLRSLDAY 594

Query: 750  PVLAEDAQRLFTALFPFEKNCGNDNICQDDLSITFSFMSLDCLVVG------GPREFNVT 803
            P+L +           F+K CG DN C+ +L +  +F+S     +         R+  ++
Sbjct: 595  PILNQAQALENHTEVQFQKECGPDNKCESNLQMRAAFVSEQQQKLSRLQYSRDVRKLLLS 654

Query: 804  VTVRN------DGEDSYRTQVTFFFPLDLSYRKVSTLQNQRSQRSWRLACESASSTEVSG 857
            + V N       GED++   +T   P  L    V              AC+         
Sbjct: 655  INVTNTRTSERSGEDAHEALLTLVVPPALLLSSVRPPG----------ACQ--------- 695

Query: 858  ALKSTSCSINHPIFPENSEVTFNITFDVDSKASLGNKLLLKANVTSENNMPRTNKTEFQL 917
            A ++  C + +P F  N  +   I F+V         L ++  +++ ++  + N     L
Sbjct: 696  ANETIFCELGNP-FKRNQRMELLIAFEVIGVTLHTRDLQVQLQLSTSSH--QDNLWPMIL 752

Query: 918  ELPVKYAVY--MVVTSHGVSTKY-------LNFTASENTSRVMQHQYQVSNLGQRSLPIS 968
             L V Y +   + + +H + + +             E+    +++++QV  +G+  + + 
Sbjct: 753  TLLVDYTLQTSLSMVNHRLQSFFGGTVMGESGMKTVEDVGSPLKYEFQVGPMGEGLVGLG 812

Query: 969  -----------------LVFLVPVRLNQTVIWD-RPQVTFSENLSSTCHTKERLPSHSD- 1009
                             L++   + ++    W  RP       L+ T       PS    
Sbjct: 813  TLVLGLEWPYEVSNGKWLLYPTEITVHGNGSWPCRPPGDLINPLNLTLSDPGDRPSSPQR 872

Query: 1010 ----------------FLAELRKA---PVVNCSI--AVCQRIQCDIPFFGIQEEFNATLK 1048
                             LA  +KA    V+ C+   A C  ++C IP   +    N T+K
Sbjct: 873  RRRQLDPGGGQGPPPVTLAAAKKAKSETVLTCATGRAHCVWLECPIPDAPVVT--NVTVK 930

Query: 1049 GNLSFDWYIK--TSHNHLLIVSTAEILFNDSVFTL-LPGQGAFVRSQTETK-VEPFEVPN 1104
              +    +I+     + + +   A +    S+ T+ +  +  +     +++ VE      
Sbjct: 931  ARVWNSTFIEDYRDFDRVRVNGWATLFLRTSIPTINMENKTTWFSVDIDSELVEELPAEI 990

Query: 1105 PLPLIVGSSVGGLLLLALITAALYKLGFFKR 1135
             L L++ +   GLLLL LI   L+K GFFKR
Sbjct: 991  ELWLVLVAVGAGLLLLGLIILLLWKCGFFKR 1021


>gi|6006011 integrin alpha 3 isoform b precursor [Homo sapiens]
          Length = 1066

 Score =  161 bits (407), Expect = 4e-39
 Identities = 209/871 (23%), Positives = 364/871 (41%), Gaps = 124/871 (14%)

Query: 347  EHEMSQEGFSAAITSNGPLLSTVGSYDWAGGVFLYTSKEKSTFINMTRVDSDMNDAYLGY 406
            E  M Q G S   T N       G+Y+W G  ++   KE        +   D  + Y+GY
Sbjct: 193  ETGMCQLGTSGGFTQNTVYFGAPGAYNWKGNSYMIQRKEWDLSEYSYKDPEDQGNLYIGY 252

Query: 407  AAAI---ILRNRVQSLVLGAPRYQHIGLVAMFRQNTGMWESNANV-KGTQIGAYFGASLC 462
               +   IL  +  ++V GAPR++H+G V +  Q  G       V +G+Q+GAYFG+++ 
Sbjct: 253  TMQVGSFILHPKNITIVTGAPRHRHMGAVFLLSQEAGGDLRRRQVLEGSQVGAYFGSAIA 312

Query: 463  SVDVDSNGSTDLVLIGAPHYYEQTR--GGQVSVCPLPRGRA-RWQCDAVLYGEQGQPWGR 519
              D++++G  DL L+GAP+Y+E+    GG + V     G +       +L+G  G     
Sbjct: 313  LADLNNDGWQDL-LVGAPYYFERKEEVGGAIYVFMNQAGTSFPAHPSLLLHGPSG---SA 368

Query: 520  FGAALTVLGDVNGDKLTDVAIGAPGEEDNRGAVYLFHGTSGSGISPSHSQRIAGSKLS-P 578
            FG ++  +GD+N D   D+A+GAP E    G VY++H +S  G+     Q I G KL  P
Sbjct: 369  FGLSVASIGDINQDGFQDIAVGAPFE--GLGKVYIYH-SSSKGLLRQPQQVIHGEKLGLP 425

Query: 579  RLQYFGQSLSGGQDLTMDGLVDLTVGA-QGHVLLLRSQPVLRV--KAIMEFNPREVARNV 635
             L  FG SLSG  D+  +   DL VG+   H++LLR++PV+ +  K ++   PR    + 
Sbjct: 426  GLATFGYSLSGQMDVDENFYPDLLVGSLSDHIVLLRARPVINIVHKTLV---PRPAVLDP 482

Query: 636  FECNDQVVKGKEAGEVRVCLHVQKSTRDRLREGQIQSVVTYDLALDSGRPHSRAVFNETK 695
              C           +V +C    +S  +      I   + Y L  D  R   R  F  ++
Sbjct: 483  ALCT-----ATSCVQVELCFAYNQSAGNPNYRRNI--TLAYTLEADRDRRPPRLRFAGSE 535

Query: 696  NSTRRQTQVLGLTQTCETLKLQLPNCIEDPVSPIVLRLNFSL-VGTPLSAFGNLR----- 749
            ++       +     C+ L+L L + + D + PI++ +N+SL +  P      LR     
Sbjct: 536  SAVFHGFFSMP-EMRCQKLELLLMDNLRDKLRPIIISMNYSLPLRMPDRPRLGLRSLDAY 594

Query: 750  PVLAEDAQRLFTALFPFEKNCGNDNICQDDLSITFSFMSLDCLVVG------GPREFNVT 803
            P+L +           F+K CG DN C+ +L +  +F+S     +         R+  ++
Sbjct: 595  PILNQAQALENHTEVQFQKECGPDNKCESNLQMRAAFVSEQQQKLSRLQYSRDVRKLLLS 654

Query: 804  VTVRN------DGEDSYRTQVTFFFPLDLSYRKVSTLQNQRSQRSWRLACESASSTEVSG 857
            + V N       GED++   +T   P  L    V              AC+         
Sbjct: 655  INVTNTRTSERSGEDAHEALLTLVVPPALLLSSVRPPG----------ACQ--------- 695

Query: 858  ALKSTSCSINHPIFPENSEVTFNITFDVDSKASLGNKLLLKANVTSENNMPRTNKTEFQL 917
            A ++  C + +P F  N  +   I F+V         L ++  +++ ++  + N     L
Sbjct: 696  ANETIFCELGNP-FKRNQRMELLIAFEVIGVTLHTRDLQVQLQLSTSSH--QDNLWPMIL 752

Query: 918  ELPVKYAVY--MVVTSHGVSTKY-------LNFTASENTSRVMQHQYQVSNLGQRSLPIS 968
             L V Y +   + + +H + + +             E+    +++++QV  +G+  + + 
Sbjct: 753  TLLVDYTLQTSLSMVNHRLQSFFGGTVMGESGMKTVEDVGSPLKYEFQVGPMGEGLVGLG 812

Query: 969  -----------------LVFLVPVRLNQTVIWD-RPQVTFSENLSSTCHTKERLPSHSD- 1009
                             L++   + ++    W  RP       L+ T       PS    
Sbjct: 813  TLVLGLEWPYEVSNGKWLLYPTEITVHGNGSWPCRPPGDLINPLNLTLSDPGDRPSSPQR 872

Query: 1010 ----------------FLAELRKA---PVVNCSI--AVCQRIQCDIPFFGIQEEFNATLK 1048
                             LA  +KA    V+ C+   A C  ++C IP   +    N T+K
Sbjct: 873  RRRQLDPGGGQGPPPVTLAAAKKAKSETVLTCATGRAHCVWLECPIPDAPVVT--NVTVK 930

Query: 1049 GNLSFDWYIK--TSHNHLLIVSTAEILFNDSVFTL-LPGQGAFVRSQTETK-VEPFEVPN 1104
              +    +I+     + + +   A +    S+ T+ +  +  +     +++ VE      
Sbjct: 931  ARVWNSTFIEDYRDFDRVRVNGWATLFLRTSIPTINMENKTTWFSVDIDSELVEELPAEI 990

Query: 1105 PLPLIVGSSVGGLLLLALITAALYKLGFFKR 1135
             L L++ +   GLLLL LI   L+K  FFKR
Sbjct: 991  ELWLVLVAVGAGLLLLGLIILLLWKCDFFKR 1021


>gi|119395742 integrin alpha chain, alpha 6 isoform b precursor [Homo
            sapiens]
          Length = 1073

 Score =  155 bits (393), Expect = 2e-37
 Identities = 216/902 (23%), Positives = 387/902 (42%), Gaps = 156/902 (17%)

Query: 352  QEGFSAAITSNGPLL--STVGSYDWAGGVFLYTSKEKSTFINM-------------TRVD 396
            Q+G +A  T +   +     G+Y+W G   +   ++ +TF +M             T  D
Sbjct: 189  QQGVAATFTKDFHYIVFGAPGTYNWKG--IVRVEQKNNTFFDMNIFEDGPYEVGGETEHD 246

Query: 397  SDM----NDAYLGYAA----AIILRNRVQSLVLGAPRYQHIGLVAMFRQNTGMWESNANV 448
              +     ++YLG++      I+ ++ + + V GAPR  H G V + +++      +A++
Sbjct: 247  ESLVPVPANSYLGFSLDSGKGIVSKDEI-TFVSGAPRANHSGAVVLLKRDM----KSAHL 301

Query: 449  ------KGTQIGAYFGASLCSVDVDSNGSTDLVLIGAPHYYEQTR--GGQVSVCPLPRGR 500
                   G  + + FG  +  VD++ +G  D+V IGAP Y+++    GG V V    +GR
Sbjct: 302  LPEHIFDGEGLASSFGYDVAVVDLNKDGWQDIV-IGAPQYFDRDGEVGGAVYVYMNQQGR 360

Query: 501  ARWQCDAVLYGEQGQPWGRFGAALTVLGDVNGDKLTDVAIGAPGEEDNRGAVYLFHGTSG 560
                    L G +      FG A+  +GD+N D   D+A+GAP   D+ G V+++HG S 
Sbjct: 361  WNNVKPIRLNGTKDS---MFGIAVKNIGDINQDGYPDIAVGAP--YDDLGKVFIYHG-SA 414

Query: 561  SGISPSHSQRIAGSKLSPRLQYFGQSLSGGQDLTMDGLVDLTVGA-QGHVLLLRSQPVLR 619
            +GI+   +Q + G  +SP   YFG S++G  DL  +   D+ VG+    V + RS+PV+ 
Sbjct: 415  NGINTKPTQVLKG--ISP---YFGYSIAGNMDLDRNSYPDVAVGSLSDSVTIFRSRPVIN 469

Query: 620  VKAIMEFNPREVARNVFECNDQVVKGKEAGEVRVCLHVQKSTRDRLREGQIQSVVTYDLA 679
            ++  +   P  +     +   +   G  +G   +CL V+               ++    
Sbjct: 470  IQKTITVTPNRI-----DLRQKTACGAPSG---ICLQVKSCFEYTANPAGYNPSISIVGT 521

Query: 680  LDSGRPHSRAVFNE-----TKNSTRRQTQVLGLTQ----TCETLKLQLPNCIEDPVSPIV 730
            L++ +   ++  +       + S  + TQ L L +     C    L L + I D + PI 
Sbjct: 522  LEAEKERRKSGLSSRVQFRNQGSEPKYTQELTLKRQKQKVCMEETLWLQDNIRDKLRPIP 581

Query: 731  LRLNFSLVGTP----LSAFGNLRPVLAEDAQRLFTALFPFEKN-CGNDNICQDDLSITFS 785
            +  +  +        +++   + P+L  D  +       F K  CG+DN+C  +L + + 
Sbjct: 582  ITASVEIQEPSSRRRVNSLPEVLPILNSDEPKTAHIDVHFLKEGCGDDNVCNSNLKLEYK 641

Query: 786  FMSLDC----------------LVVGGPREFNVTVTVRN----------DGEDSYRTQVT 819
            F + +                 LV+   ++  + +TV N          DG+D++  ++ 
Sbjct: 642  FCTREGNQDKFSYLPIQKGVPELVLKDQKDIALEITVTNSPSNPRNPTKDGDDAHEAKLI 701

Query: 820  FFFPLDLSYRKVSTLQNQRSQRSWRLACESASSTEVSGALKSTSCSINHPIFPENSEVTF 879
              FP  L+Y   S  +  R+    +L+C +  +           C + +P F  NS VTF
Sbjct: 702  ATFPDTLTY---SAYRELRAFPEKQLSCVANQNGS------QADCELGNP-FKRNSNVTF 751

Query: 880  -------NITFDVDSKASLGNKLLLKANVTSENNMPRTNKTEFQLELPVKYA-------V 925
                    +TFD      L   L L+     +N  P T K +  +EL +  +       V
Sbjct: 752  YLVLSTTEVTFDTPD---LDINLKLETTSNQDNLAPITAKAKVVIELLLSVSGVAKPSQV 808

Query: 926  YM---VVTSHGVSTKYLNFTASENTSRVMQHQYQVSNLGQRSLPIS----------LVFL 972
            Y    VV    + ++    +  E   RV+     ++NLG  +L I           L++L
Sbjct: 809  YFGGTVVGEQAMKSEDEVGSLIEYEFRVINLGKPLTNLGTATLNIQWPKEISNGKWLLYL 868

Query: 973  VPVRLN--QTVIWDRPQVTFSENLSSTCH-------TKERLPSHSDF-LAELRKAPVVNC 1022
            V V     + V  +  +   S NL+ + +       T++++  +  F L   RK   +NC
Sbjct: 869  VKVESKGLEKVTCEPQKEINSLNLTESHNSRKKREITEKQIDDNRKFSLFAERKYQTLNC 928

Query: 1023 SIAV-CQRIQCDIPFFGIQEEFNATLKGNLSFDWYIK--TSHNHLLIVSTAEILFNDSVF 1079
            S+ V C  I+C  P  G+  + +  L+  L    +++  +  N+L I+  A I    +  
Sbjct: 929  SVNVNCVNIRC--PLRGLDSKASLILRSRLWNSTFLEEYSKLNYLDILMRAFIDVTAAAE 986

Query: 1080 TL-LPGQGAFVRSQT-ETKVEPFEVPNPLPLIVGSSVGGLLLLALITAALYKLGFFKRQY 1137
             + LP  G  VR     +K        P  +I+ + + G+L+LAL+   L+K GFFKR  
Sbjct: 987  NIRLPNAGTQVRVTVFPSKTVAQYSGVPWWIILVAILAGILMLALLVFILWKCGFFKRNK 1046

Query: 1138 KD 1139
            KD
Sbjct: 1047 KD 1048



 Score = 31.6 bits (70), Expect = 4.5
 Identities = 35/139 (25%), Positives = 59/139 (42%), Gaps = 24/139 (17%)

Query: 17  FNLDTEN---AMTFQENARGFGQSVV---QLQGSR---VVVGAPQE----IVAANQRGSL 63
           FNLDT        + +    FG S+    QLQ      ++VGAP+     +  AN+ G L
Sbjct: 24  FNLDTREDNVIRKYGDPGSLFGFSLAMHWQLQPEDKRLLLVGAPRAEALPLQRANRTGGL 83

Query: 64  YQCDYST-GSCEPIRLQVPVEAVNMS-----LGLSLAATTSPPQLLACGPTVHQ-----T 112
           Y CD +  G C  I      +  + S     +G+++ +     +++ C     +     T
Sbjct: 84  YSCDITARGPCTRIEFDNDADPTSESKEDQWMGVTVQSQGPGGKVVTCAHRYEKRQHVNT 143

Query: 113 CSENTYVKGLCFLFGSNLR 131
             E+  + G C++   NLR
Sbjct: 144 KQESRDIFGRCYVLSQNLR 162


>gi|119395740 integrin alpha chain, alpha 6 isoform a precursor [Homo
            sapiens]
          Length = 1091

 Score =  153 bits (386), Expect = 1e-36
 Identities = 217/902 (24%), Positives = 387/902 (42%), Gaps = 156/902 (17%)

Query: 352  QEGFSAAITSNGPLL--STVGSYDWAGGVFLYTSKEKSTFINM-------------TRVD 396
            Q+G +A  T +   +     G+Y+W G   +   ++ +TF +M             T  D
Sbjct: 189  QQGVAATFTKDFHYIVFGAPGTYNWKG--IVRVEQKNNTFFDMNIFEDGPYEVGGETEHD 246

Query: 397  SDM----NDAYLGYAA----AIILRNRVQSLVLGAPRYQHIGLVAMFRQNTGMWESNANV 448
              +     ++YLG++      I+ ++ + + V GAPR  H G V + +++      +A++
Sbjct: 247  ESLVPVPANSYLGFSLDSGKGIVSKDEI-TFVSGAPRANHSGAVVLLKRDM----KSAHL 301

Query: 449  ------KGTQIGAYFGASLCSVDVDSNGSTDLVLIGAPHYYEQTR--GGQVSVCPLPRGR 500
                   G  + + FG  +  VD++ +G  D+V IGAP Y+++    GG V V    +GR
Sbjct: 302  LPEHIFDGEGLASSFGYDVAVVDLNKDGWQDIV-IGAPQYFDRDGEVGGAVYVYMNQQGR 360

Query: 501  ARWQCDAVLYGEQGQPWGRFGAALTVLGDVNGDKLTDVAIGAPGEEDNRGAVYLFHGTSG 560
                    L G +      FG A+  +GD+N D   D+A+GAP   D+ G V+++HG S 
Sbjct: 361  WNNVKPIRLNGTKDS---MFGIAVKNIGDINQDGYPDIAVGAP--YDDLGKVFIYHG-SA 414

Query: 561  SGISPSHSQRIAGSKLSPRLQYFGQSLSGGQDLTMDGLVDLTVGA-QGHVLLLRSQPVLR 619
            +GI+   +Q + G  +SP   YFG S++G  DL  +   D+ VG+    V + RS+PV+ 
Sbjct: 415  NGINTKPTQVLKG--ISP---YFGYSIAGNMDLDRNSYPDVAVGSLSDSVTIFRSRPVIN 469

Query: 620  VKAIMEFNPREVARNVFECNDQVVKGKEAGEVRVCLHVQKSTRDRLREGQIQSVVTYDLA 679
            ++  +   P     N  +   +   G  +G   +CL V+               ++    
Sbjct: 470  IQKTITVTP-----NRIDLRQKTACGAPSG---ICLQVKSCFEYTANPAGYNPSISIVGT 521

Query: 680  LDSGRPH-----SRAVFNETKNSTRRQTQVLGL----TQTCETLKLQLPNCIEDPVSPIV 730
            L++ +       S  V    + S  + TQ L L     + C    L L + I D + PI 
Sbjct: 522  LEAEKERRKSGLSSRVQFRNQGSEPKYTQELTLKRQKQKVCMEETLWLQDNIRDKLRPIP 581

Query: 731  LRLNFSLVGTP----LSAFGNLRPVLAEDAQRLFTALFPF-EKNCGNDNICQDDLSITFS 785
            +  +  +        +++   + P+L  D  +       F ++ CG+DN+C  +L + + 
Sbjct: 582  ITASVEIQEPSSRRRVNSLPEVLPILNSDEPKTAHIDVHFLKEGCGDDNVCNSNLKLEYK 641

Query: 786  FMSLDC----------------LVVGGPREFNVTVTVRN----------DGEDSYRTQVT 819
            F + +                 LV+   ++  + +TV N          DG+D++  ++ 
Sbjct: 642  FCTREGNQDKFSYLPIQKGVPELVLKDQKDIALEITVTNSPSNPRNPTKDGDDAHEAKLI 701

Query: 820  FFFPLDLSYRKVSTLQNQRSQRSWRLACESASSTEVSGALKSTSCSINHPIFPENSEVTF 879
              FP  L+Y   S  +  R+    +L+C +  +           C + +P F  NS VTF
Sbjct: 702  ATFPDTLTY---SAYRELRAFPEKQLSCVANQNG------SQADCELGNP-FKRNSNVTF 751

Query: 880  -------NITFDVDSKASLGNKLLLKANVTSENNMPRTNKTEFQLELPVKYA-------V 925
                    +TFD      L   L L+     +N  P T K +  +EL +  +       V
Sbjct: 752  YLVLSTTEVTFDT---PDLDINLKLETTSNQDNLAPITAKAKVVIELLLSVSGVAKPSQV 808

Query: 926  YM---VVTSHGVSTKYLNFTASENTSRVMQHQYQVSNLGQRSLPIS----------LVFL 972
            Y    VV    + ++    +  E   RV+     ++NLG  +L I           L++L
Sbjct: 809  YFGGTVVGEQAMKSEDEVGSLIEYEFRVINLGKPLTNLGTATLNIQWPKEISNGKWLLYL 868

Query: 973  VPVRLN--QTVIWDRPQVTFSENLSSTCH-------TKERLPSHSDF-LAELRKAPVVNC 1022
            V V     + V  +  +   S NL+ + +       T++++  +  F L   RK   +NC
Sbjct: 869  VKVESKGLEKVTCEPQKEINSLNLTESHNSRKKREITEKQIDDNRKFSLFAERKYQTLNC 928

Query: 1023 SIAV-CQRIQCDIPFFGIQEEFNATLKGNLSFDWYIK--TSHNHLLIVSTAEILFNDSVF 1079
            S+ V C  I+C  P  G+  + +  L+  L    +++  +  N+L I+  A I    +  
Sbjct: 929  SVNVNCVNIRC--PLRGLDSKASLILRSRLWNSTFLEEYSKLNYLDILMRAFIDVTAAAE 986

Query: 1080 TL-LPGQGAFVR-SQTETKVEPFEVPNPLPLIVGSSVGGLLLLALITAALYKLGFFKRQY 1137
             + LP  G  VR +   +K        P  +I+ + + G+L+LAL+   L+K GFFKR  
Sbjct: 987  NIRLPNAGTQVRVTVFPSKTVAQYSGVPWWIILVAILAGILMLALLVFILWKCGFFKRSR 1046

Query: 1138 KD 1139
             D
Sbjct: 1047 YD 1048



 Score = 31.6 bits (70), Expect = 4.5
 Identities = 35/139 (25%), Positives = 59/139 (42%), Gaps = 24/139 (17%)

Query: 17  FNLDTEN---AMTFQENARGFGQSVV---QLQGSR---VVVGAPQE----IVAANQRGSL 63
           FNLDT        + +    FG S+    QLQ      ++VGAP+     +  AN+ G L
Sbjct: 24  FNLDTREDNVIRKYGDPGSLFGFSLAMHWQLQPEDKRLLLVGAPRAEALPLQRANRTGGL 83

Query: 64  YQCDYST-GSCEPIRLQVPVEAVNMS-----LGLSLAATTSPPQLLACGPTVHQ-----T 112
           Y CD +  G C  I      +  + S     +G+++ +     +++ C     +     T
Sbjct: 84  YSCDITARGPCTRIEFDNDADPTSESKEDQWMGVTVQSQGPGGKVVTCAHRYEKRQHVNT 143

Query: 113 CSENTYVKGLCFLFGSNLR 131
             E+  + G C++   NLR
Sbjct: 144 KQESRDIFGRCYVLSQNLR 162


>gi|49170034 integrin, alpha 8 [Homo sapiens]
          Length = 1063

 Score =  152 bits (384), Expect = 2e-36
 Identities = 204/868 (23%), Positives = 363/868 (41%), Gaps = 111/868 (12%)

Query: 352  QEGFSAAITSNGPLL-STVGSYDWAGGVFL---------YTSKE---KSTFINMTRV-DS 397
            Q GFS     NG L+    GS+ W G V           Y+ K+   K      T V  +
Sbjct: 201  QAGFSLDFYKNGDLIVGGPGSFYWQGQVITASVADIIANYSFKDILRKLAGEKQTEVAPA 260

Query: 398  DMNDAYLGY--AAAIILRNRVQSLVLGAPR-YQHIGLVAMFRQNTGMWESNANVKGTQIG 454
              +D+YLGY  AA     +  Q LV G PR  Q+ G V++   N+       N  G Q+ 
Sbjct: 261  SYDDSYLGYSVAAGEFTGDSQQELVAGIPRGAQNFGYVSII--NSTDMTFIQNFTGEQMA 318

Query: 455  AYFGASLCSVDVDSNGSTDLVLIGAPHYYEQT------RGGQVSVCPLPRGRARWQCDAV 508
            +YFG ++   DV+S+G  D VL+GAP + E+         GQ+ +  L      ++   +
Sbjct: 319  SYFGYTVVVSDVNSDGLDD-VLVGAPLFMEREFESNPREVGQIYLY-LQVSSLLFRDPQI 376

Query: 509  LYGEQGQPWGRFGAALTVLGDVNGDKLTDVAIGAP-GEEDNRGAVYLFHGTSGSGISPSH 567
            L G +   +GRFG+A+  LGD+N D   D+AIG P   +D RG V +++G    G++   
Sbjct: 377  LTGTE--TFGRFGSAMAHLGDLNQDGYNDIAIGVPFAGKDQRGKVLIYNGNK-DGLNTKP 433

Query: 568  SQRIAGSKLSPRL-QYFGQSLSGGQDLTMDGLVDLTVGA--QGHVLLLRSQPVLRVKAIM 624
            SQ + G   S  +   FG +L G  D+  +   DL VGA   G V + R++PV+ V A +
Sbjct: 434  SQVLQGVWASHAVPSGFGFTLRGDSDIDKNDYPDLIVGAFGTGKVAVYRARPVVTVDAQL 493

Query: 625  EFNPREVARNVFECN-DQVVKGKEAGEVRVCLHVQ----KSTRDRLREGQIQSV-----V 674
              +P  +      C     +       +RVC  V      +T   + E Q+ S+     +
Sbjct: 494  LLHPMIINLENKTCQVPDSMTSAACFSLRVCASVTGQSIANTIVLMAEVQLDSLKQKGAI 553

Query: 675  TYDLALDSGRPHS-RAVFNETKNSTRRQTQVLGLTQTCETLKLQLPNCIEDPVSPIVLRL 733
               L LD+ + H    +  + + S + Q  ++ L    E           D +SPI + L
Sbjct: 554  KRTLFLDNHQAHRVFPLVIKRQKSHQCQDFIVYLRDETE---------FRDKLSPINISL 604

Query: 734  NFSLVGTPLSAFGNLRPVLAEDAQRLFTALFPFEKNCGNDNICQDDLSITFSFMSLDCLV 793
            N+SL  +       ++P+L    + + +       +CG DN+C  DL ++ +      ++
Sbjct: 605  NYSLDESTFKEGLEVKPILNYYRENIVSEQAHILVDCGEDNLCVPDLKLS-ARPDKHQVI 663

Query: 794  VGGPREFNVTVTVRNDGEDSYRTQVTFFFPLDLSYRKVSTLQNQRSQRSWR-LACESASS 852
            +G      + +  RN+GE +Y  ++    P +  Y  +     +R+ + +R L+CE    
Sbjct: 664  IGDENHLMLIINARNEGEGAYEAELFVMIPEEADYVGI-----ERNNKGFRPLSCE---- 714

Query: 853  TEVSGALKSTSCSINHPIFPENSEVTFNITFDVDSKASLGNKLLLKANVTSEN-NMPRTN 911
             ++    +   C + +P+    +  +  + F V         +     + S N + P +N
Sbjct: 715  YKMENVTRMVVCDLGNPMV-SGTNYSLGLRFAVPRLEKTNMSINFDLQIRSSNKDNPDSN 773

Query: 912  KTEFQLELPVKYAVYMVVTSH--GVSTKYLNFTASENTSR------VMQHQYQVSNLGQR 963
                Q+ +     V +   SH   +     N+   E   +      +++H Y++ N+G  
Sbjct: 774  FVSLQINITAVAQVEIRGVSHPPQIVLPIHNWEPEEEPHKEEEVGPLVEHIYELHNIGPS 833

Query: 964  SLPISLV-----------FLVPVRLNQTV--IWDRPQVTFSENLSSTCHTKERLPSHSDF 1010
            ++  +++           FL+ +   QT+  +  +P    +        + E  P  S F
Sbjct: 834  TISDTILEVGWPFSARDEFLLYIFHIQTLGPLQCQPNPNINPQDIKPAASPEDTPELSAF 893

Query: 1011 LAE------LRK-------------APVVNCSIAVCQRIQCDIPFFGIQEEFNATLKGNL 1051
            L        +RK             A ++NC+   C +I C +      E     ++  L
Sbjct: 894  LRNSTIPHLVRKRDVHVVEFHRQSPAKILNCTNIECLQISCAVGRLEGGESAVLKVRSRL 953

Query: 1052 SFDWYIKTSHNHLLIVSTAEILFNDSVFT----LLPGQGAFVRSQTETKVEPFEVPNPLP 1107
                +++  ++   + S          +T     LP     +++             PL 
Sbjct: 954  WAHTFLQRKNDPYALASLVSFEVKKMPYTDQPAKLPEGSIAIKTSVIWATPNVSFSIPLW 1013

Query: 1108 LIVGSSVGGLLLLALITAALYKLGFFKR 1135
            +I+ + + GLL+LA++T AL+K GFF R
Sbjct: 1014 VIILAILLGLLVLAILTLALWKCGFFDR 1041


>gi|88758615 integrin alpha 2b preproprotein [Homo sapiens]
          Length = 1039

 Score =  145 bits (366), Expect = 2e-34
 Identities = 212/890 (23%), Positives = 351/890 (39%), Gaps = 154/890 (17%)

Query: 345  SFEHEMSQEGFSAAITSNGPL-LSTVGSYDWAG----------------GVFLYTSKEKS 387
            S++    + GFS+ +T  G L L   G Y + G                G+ L+    +S
Sbjct: 192  SWDKRYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVADIFSSYRPGILLWHVSSQS 251

Query: 388  TFINMTRVDSDMNDAYLGYAAAIILRN---RVQSLVLGAPRYQH-IGLVAMFRQNTGMWE 443
              ++    + +  D Y GY+ A+   +        V+GAP +   +G V +       ++
Sbjct: 252  --LSFDSSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEIL---DSYYQ 306

Query: 444  SNANVKGTQIGAYFGASLCSVDVDSNGSTDLVLIGAPHYYEQTRG------GQVSVCPLP 497
                ++G Q+ +YFG S+   DV+ +G  DL L+GAP Y E          G+V +   P
Sbjct: 307  RLHRLRGEQMASYFGHSVAVTDVNGDGRHDL-LVGAPLYMESRADRKLAEVGRVYLFLQP 365

Query: 498  RGRARWQCDAVLYGEQGQPWGRFGAALTVLGDVNGDKLTDVAIGAP-GEEDNRGAVYLFH 556
            RG       ++L     Q +GRFG+A+  LGD++ D   D+A+ AP G    RG V +F 
Sbjct: 366  RGPHALGAPSLLLTGT-QLYGRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQVLVFL 424

Query: 557  GTSGSGISPSHSQRIAGSKLSPRLQYFGQSLSGGQDLTMDGLVDLTVGAQG--HVLLLRS 614
            G S  G+    SQ +      P    FG SL G  D+  +G  DL VGA G   V + R+
Sbjct: 425  GQS-EGLRSRPSQVLDSP--FPTGSAFGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYRA 481

Query: 615  QPVLRVKAIMEFNPREVARNVFECNDQVVKGKEAGEVRV---CLHVQKSTRDRLREGQIQ 671
            QPV++           V   V +  +  VK     + +    C ++Q            +
Sbjct: 482  QPVVKAS---------VQLLVQDSLNPAVKSCVLPQTKTPVSCFNIQMCVGATGHNIPQK 532

Query: 672  SVVTYDLALDSGRPHSRAVFNETKNSTRRQTQVLGLTQTCETLKLQL-----PNC----- 721
              +  +L LD  +P              R+  +LG  Q   TL L L     P C     
Sbjct: 533  LSLNAELQLDRQKPRQG-----------RRVLLLGSQQAGTTLNLDLGGKHSPICHTTMA 581

Query: 722  -------IEDPVSPIVLRLNFSLVGTPLSAFGNLRPVLAEDAQRLFTALFPFEKNCGNDN 774
                     D +SPIVL LN SL  T       + P +                +CG D+
Sbjct: 582  FLRDEADFRDKLSPIVLSLNVSLPPTE----AGMAPAVVLHGDTHVQEQTRIVLDCGEDD 637

Query: 775  ICQDDLSITFSFMSLDCLVVGGPREFNVTVTVRNDGEDSYRTQVTFFFPLDLSY-RKVST 833
            +C   L +T S      L+VG      + +   N+GE +Y  ++    P    Y R +S 
Sbjct: 638  VCVPQLQLTASVTGSP-LLVGADNVLELQMDAANEGEGAYEAELAVHLPQGAHYMRALSN 696

Query: 834  LQNQRSQRSWRLACESASSTEVSGALKSTSCSINHPIFPENSEVTFNITFDVDSKASLGN 893
            ++        RL C      E    L    C + +P+  +N+++   +   V +    G 
Sbjct: 697  VEGFE-----RLICNQKKENETRVVL----CELGNPM-KKNAQIGIAMLVSVGNLEEAGE 746

Query: 894  KLLLKANVTSENNMPRTNKTEFQLELPVKYAVYMVVTSHGVSTKYLNFTASENTSR---- 949
             +  +  + S+N+    +K    L++PV+    + +  +      +   A+E   R    
Sbjct: 747  SVSFQLQIRSKNSQNPNSKIVL-LDVPVRAEAQVELRGNSFPASLV--VAAEEGEREQNS 803

Query: 950  ------VMQHQYQVSNLGQ--------------RSLPISLVFLVPVRLN----------- 978
                   ++H Y++ N G               +S P  L++++ ++             
Sbjct: 804  LDSWGPKVEHTYELHNNGPGTVNGLHLSIHLPGQSQPSDLLYILDIQPQGGLQCFPQPPV 863

Query: 979  --QTVIWDRPQVTFSENLSSTCHTKER----LPSHSDFLAELRKAPVVNCSIAVCQRIQC 1032
                V W  P +     +    H ++R    LP   +  + L+   +V+C  A C  +QC
Sbjct: 864  NPLKVDWGLP-IPSPSPIHPAHHKRDRRQIFLP-EPEQPSRLQDPVLVSCDSAPCTVVQC 921

Query: 1033 DIPFFGIQEEFNATLKGNLSFDWYIKTSHNHL-LIVSTAEILFNDSVFTL------LPGQ 1085
            D+      +    T+   L+F W        L   V  +   FN S          LP  
Sbjct: 922  DLQEMARGQRAMVTV---LAFLWLPSLYQRPLDQFVLQSHAWFNVSSLPYAVPPLSLPRG 978

Query: 1086 GAFVRSQTETKVEPFEVPNPLPLIVGSSVGGLLLLALITAALYKLGFFKR 1135
             A V +Q    +E  E   P+  ++   +GGLLLL ++  A++K+GFFKR
Sbjct: 979  EAQVWTQLLRALE--ERAIPIWWVLVGVLGGLLLLTILVLAMWKVGFFKR 1026


>gi|222418611 integrin alpha 7 isoform 2 precursor [Homo sapiens]
          Length = 1137

 Score =  137 bits (345), Expect = 6e-32
 Identities = 206/901 (22%), Positives = 359/901 (39%), Gaps = 148/901 (16%)

Query: 352  QEGFSAAIT--SNGPLLSTVGSYDWAGGVFLYT--SKEKSTFINMTRVDSDMN------- 400
            Q+G +AA +  S+  L    G+Y+W G +F+    S +    +  T   +D         
Sbjct: 198  QQGTAAAFSPDSHYLLFGAPGTYNWKGLLFVTNIDSSDPDQLVYKTLDPADRLPGPAGDL 257

Query: 401  --DAYLGYAAAI---ILRNRVQSLVLGAPRYQHIGLVAMFRQNTGM-WESNANVKGTQIG 454
              ++YLG++      ++R    S V GAPR  H G V + R+++         + G ++ 
Sbjct: 258  ALNSYLGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKDSASRLVPEVMLSGERLT 317

Query: 455  AYFGASLCSVDVDSNGSTDLVLIGAPHYYEQTR--GGQVSVCPLPRGRARWQCDAVLYGE 512
            + FG SL   D++S+G  DL+ +GAP+++E+    GG V V  L +G   W   + L   
Sbjct: 318  SGFGYSLAVADLNSDGWPDLI-VGAPYFFERQEELGGAVYVY-LNQG-GHWAGISPLR-L 373

Query: 513  QGQPWGRFGAALTVLGDVNGDKLTDVAIGAPGEEDNRGAVYLFHGTSGSGISPSHSQRIA 572
             G P   FG +L VLGD+N D   D+A+GAP + D  G V+++HG+S  G+    SQ + 
Sbjct: 374  CGSPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGD--GKVFIYHGSS-LGVVAKPSQVLE 430

Query: 573  GSKLSPRLQYFGQSLSGGQDLTMDGLVDLTVGAQGH-VLLLRSQPVLRVKAIMEFNPREV 631
            G  +   ++ FG SLSG  D+  +   DL VG+     +L R++P+L V   +   PR +
Sbjct: 431  GEAVG--IKSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHEVSIAPRSI 488

Query: 632  ARNVFECNDQVVKGKEAGEVRVCLHVQKSTRDRLREGQIQSVVTYDLALDSG-----RPH 686
                  C         AG   VC+ ++               V  D  LD+      R  
Sbjct: 489  DLEQPNC---------AGGHSVCVDLRVCFSYIAVPSSYSPTVALDYVLDADTDRRLRGQ 539

Query: 687  SRAVFNETKNSTRRQTQVLGLT-------QTCETLKLQLPNCIEDPVSPIVLRLNFSLV- 738
               V   ++N    + Q  G         + C     QL   ++D +  IV+ L++SL  
Sbjct: 540  VPRVTFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVTLSYSLQT 599

Query: 739  -----GTPLSAFGNLRPVL-AEDAQRLFTALFPFEKNCGNDNICQDDLSIT--------- 783
                   P      + P+L A         +   ++ CG D ICQ +L +          
Sbjct: 600  PRLRRQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRVS 659

Query: 784  ---FSFMSLD------CLVVGGPREFNVTVTVRN----------DGEDSYRTQVTFFFPL 824
               F  + +D         + G     + + V N          DG+D++  Q+    P 
Sbjct: 660  DTEFQPLPMDVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLPD 719

Query: 825  DLSYRKVSTLQNQRSQRSWRLACESASSTEVSGALKSTSCSINHPIFPENSEVTFNITFD 884
             L Y  V  L    +++   L+ E+AS  E         C + +P+    ++VTF +   
Sbjct: 720  SLHYSGVRAL--DPAEKPLCLSNENASHVE---------CELGNPM-KRGAQVTFYLILS 767

Query: 885  VDSKASLGNKL---LLKANVTSENNMPRTNKTEFQLELPVK---YAVYMVVTSHGVSTKY 938
                +    +L   LL A ++ +   P + +    +ELP+     A+   +   GV    
Sbjct: 768  TSGISIETTELEVELLLATISEQELHPVSARARVFIELPLSIAGMAIPQQLFFSGVVRGE 827

Query: 939  LNFTASENTSRVMQHQYQVSNLGQRSLPISLVF---------------LVPVRL------ 977
                +  +    ++++  VSN GQ    +   F               L P+++      
Sbjct: 828  RAMQSERDVGSKVKYEVTVSNQGQSLRTLGSAFLNIMWPHEIANGKWLLYPMQVELEGGQ 887

Query: 978  ---NQTVIWDRPQVTFSENLSSTCHTKERLPSHSD---------------FLAELRKAPV 1019
                + +   RP +   +  S     +E  P                     AE +K   
Sbjct: 888  GPGQKGLCSPRPNILHLDVDSRDRRRRELEPPEQQEPGERQEPSMSWWPVSSAEKKKNIT 947

Query: 1020 VNCSIAVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYIK--TSHNHLLIVSTAEILFNDS 1077
            ++C+      +    P +         + G L    +++  ++   L ++  A I    S
Sbjct: 948  LDCARGTANCVVFSCPLYSFDRAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRANITVKSS 1007

Query: 1078 VFTLLPGQGAFVRSQTETKVEPFEVPN---PLPLIVGSSVGGLLLLALITAALYKLGFFK 1134
            +  L+    + V       ++P  V     P  +I+ + + GLL+LAL+   L+K+GFFK
Sbjct: 1008 IKNLMLRDASTV-IPVMVYLDPMAVVAEGVPWWVILLAVLAGLLVLALLVLLLWKMGFFK 1066

Query: 1135 R 1135
            R
Sbjct: 1067 R 1067


>gi|222418615 integrin alpha 7 isoform 3 [Homo sapiens]
          Length = 1044

 Score =  131 bits (329), Expect = 4e-30
 Identities = 204/907 (22%), Positives = 356/907 (39%), Gaps = 156/907 (17%)

Query: 352  QEGFSAAIT--SNGPLLSTVGSYDWAGGVFLYTSKEKSTFINMTRVDSDMNDA------- 402
            Q+G +AA +  S+  L    G+Y+W G   +    + S   ++  +D    +A       
Sbjct: 101  QQGTAAAFSPDSHYLLFGAPGTYNWKGTARVELCAQGSA--DLAHLDDGPYEAGGEKEQD 158

Query: 403  ----------YLGYAAAI---ILRNRVQSLVLGAPRYQHIGLVAMFRQNTGM-WESNANV 448
                      Y G++      ++R    S V GAPR  H G V + R+++         +
Sbjct: 159  PRLIPVPANSYFGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKDSASRLVPEVML 218

Query: 449  KGTQIGAYFGASLCSVDVDSNGSTDLVLIGAPHYYEQTR--GGQVSVCPLPRGRARWQCD 506
             G ++ + FG SL   D++S+G  DL+ +GAP+++E+    GG V V  L +G   W   
Sbjct: 219  SGERLTSGFGYSLAVADLNSDGWPDLI-VGAPYFFERQEELGGAVYVY-LNQG-GHWAGI 275

Query: 507  AVLYGEQGQPWGRFGAALTVLGDVNGDKLTDVAIGAPGEEDNRGAVYLFHGTSGSGISPS 566
            + L    G P   FG +L VLGD+N D   D+A+GAP + D  G V+++HG+S  G+   
Sbjct: 276  SPLR-LCGSPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGD--GKVFIYHGSS-LGVVAK 331

Query: 567  HSQRIAGSKLSPRLQYFGQSLSGGQDLTMDGLVDLTVGAQGH-VLLLRSQPVLRVKAIME 625
             SQ + G  +   ++ FG SLSG  D+  +   DL VG+     +L R++P+L V   + 
Sbjct: 332  PSQVLEGEAVG--IKSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHEVS 389

Query: 626  FNPREVARNVFECNDQVVKGKEAGEVRVCLHVQKSTRDRLREGQIQSVVTYDLALDSG-- 683
              PR +      C         AG   VC+ ++               V  D  LD+   
Sbjct: 390  IAPRSIDLEQPNC---------AGGHSVCVDLRVCFSYIAVPSSYSPTVALDYVLDADTD 440

Query: 684  ---RPHSRAVFNETKNSTRRQTQVLGLT-------QTCETLKLQLPNCIEDPVSPIVLRL 733
               R     V   ++N    + Q  G         + C     QL   ++D +  IV+ L
Sbjct: 441  RRLRGQVPRVTFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVTL 500

Query: 734  NFSLV------GTPLSAFGNLRPVL-AEDAQRLFTALFPFEKNCGNDNICQDDLSIT--- 783
            ++SL         P      + P+L A         +   ++ CG D ICQ +L +    
Sbjct: 501  SYSLQTPRLRRQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRAR 560

Query: 784  ---------FSFMSLD------CLVVGGPREFNVTVTVRN----------DGEDSYRTQV 818
                     F  + +D         + G     + + V N          DG+D++  Q+
Sbjct: 561  FCTRVSDTEFQPLPMDVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQL 620

Query: 819  TFFFPLDLSYRKVSTLQNQRSQRSWRLACESASSTEVSGALKSTSCSINHPIFPENSEVT 878
                P  L Y  V  L    +++   L+ E+AS  E         C + +P+    ++VT
Sbjct: 621  LVMLPDSLHYSGVRAL--DPAEKPLCLSNENASHVE---------CELGNPM-KRGAQVT 668

Query: 879  FNITFDVDSKASLGNKL---LLKANVTSENNMPRTNKTEFQLELPVK---YAVYMVVTSH 932
            F +       +    +L   LL A ++ +   P + +    +ELP+     A+   +   
Sbjct: 669  FYLILSTSGISIETTELEVELLLATISEQELHPVSARARVFIELPLSIAGMAIPQQLFFS 728

Query: 933  GVSTKYLNFTASENTSRVMQHQYQVSNLGQRSLPISLVF---------------LVPVRL 977
            GV        +  +    ++++  VSN GQ    +   F               L P+++
Sbjct: 729  GVVRGERAMQSERDVGSKVKYEVTVSNQGQSLRTLGSAFLNIMWPHEIANGKWLLYPMQV 788

Query: 978  ---------NQTVIWDRPQVTFSENLSSTCHTKERLPSHSD---------------FLAE 1013
                      + +   RP +   +  S     +E  P                     AE
Sbjct: 789  ELEGGQGPGQKGLCSPRPNILHLDVDSRDRRRRELEPPEQQEPGERQEPSMSWWPVSSAE 848

Query: 1014 LRKAPVVNCSIAVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYIK--TSHNHLLIVSTAE 1071
             +K   ++C+      +    P +         + G L    +++  ++   L ++  A 
Sbjct: 849  KKKNITLDCARGTANCVVFSCPLYSFDRAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRAN 908

Query: 1072 ILFNDSVFTLLPGQGAFVRSQTETKVEPFEVPN---PLPLIVGSSVGGLLLLALITAALY 1128
            I    S+  L+    + V       ++P  V     P  +I+ + + GLL+LAL+   L+
Sbjct: 909  ITVKSSIKNLMLRDASTV-IPVMVYLDPMAVVAEGVPWWVILLAVLAGLLVLALLVLLLW 967

Query: 1129 KLGFFKR 1135
            K+GFFKR
Sbjct: 968  KMGFFKR 974


>gi|222418613 integrin alpha 7 isoform 1 precursor [Homo sapiens]
          Length = 1141

 Score =  131 bits (329), Expect = 4e-30
 Identities = 204/907 (22%), Positives = 356/907 (39%), Gaps = 156/907 (17%)

Query: 352  QEGFSAAIT--SNGPLLSTVGSYDWAGGVFLYTSKEKSTFINMTRVDSDMNDA------- 402
            Q+G +AA +  S+  L    G+Y+W G   +    + S   ++  +D    +A       
Sbjct: 198  QQGTAAAFSPDSHYLLFGAPGTYNWKGTARVELCAQGSA--DLAHLDDGPYEAGGEKEQD 255

Query: 403  ----------YLGYAAAI---ILRNRVQSLVLGAPRYQHIGLVAMFRQNTGM-WESNANV 448
                      Y G++      ++R    S V GAPR  H G V + R+++         +
Sbjct: 256  PRLIPVPANSYFGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKDSASRLVPEVML 315

Query: 449  KGTQIGAYFGASLCSVDVDSNGSTDLVLIGAPHYYEQTR--GGQVSVCPLPRGRARWQCD 506
             G ++ + FG SL   D++S+G  DL+ +GAP+++E+    GG V V  L +G   W   
Sbjct: 316  SGERLTSGFGYSLAVADLNSDGWPDLI-VGAPYFFERQEELGGAVYVY-LNQG-GHWAGI 372

Query: 507  AVLYGEQGQPWGRFGAALTVLGDVNGDKLTDVAIGAPGEEDNRGAVYLFHGTSGSGISPS 566
            + L    G P   FG +L VLGD+N D   D+A+GAP + D  G V+++HG+S  G+   
Sbjct: 373  SPLR-LCGSPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGD--GKVFIYHGSS-LGVVAK 428

Query: 567  HSQRIAGSKLSPRLQYFGQSLSGGQDLTMDGLVDLTVGAQGH-VLLLRSQPVLRVKAIME 625
             SQ + G  +   ++ FG SLSG  D+  +   DL VG+     +L R++P+L V   + 
Sbjct: 429  PSQVLEGEAVG--IKSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHEVS 486

Query: 626  FNPREVARNVFECNDQVVKGKEAGEVRVCLHVQKSTRDRLREGQIQSVVTYDLALDSG-- 683
              PR +      C         AG   VC+ ++               V  D  LD+   
Sbjct: 487  IAPRSIDLEQPNC---------AGGHSVCVDLRVCFSYIAVPSSYSPTVALDYVLDADTD 537

Query: 684  ---RPHSRAVFNETKNSTRRQTQVLGLT-------QTCETLKLQLPNCIEDPVSPIVLRL 733
               R     V   ++N    + Q  G         + C     QL   ++D +  IV+ L
Sbjct: 538  RRLRGQVPRVTFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVTL 597

Query: 734  NFSLV------GTPLSAFGNLRPVL-AEDAQRLFTALFPFEKNCGNDNICQDDLSIT--- 783
            ++SL         P      + P+L A         +   ++ CG D ICQ +L +    
Sbjct: 598  SYSLQTPRLRRQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRAR 657

Query: 784  ---------FSFMSLD------CLVVGGPREFNVTVTVRN----------DGEDSYRTQV 818
                     F  + +D         + G     + + V N          DG+D++  Q+
Sbjct: 658  FCTRVSDTEFQPLPMDVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQL 717

Query: 819  TFFFPLDLSYRKVSTLQNQRSQRSWRLACESASSTEVSGALKSTSCSINHPIFPENSEVT 878
                P  L Y  V  L    +++   L+ E+AS  E         C + +P+    ++VT
Sbjct: 718  LVMLPDSLHYSGVRAL--DPAEKPLCLSNENASHVE---------CELGNPM-KRGAQVT 765

Query: 879  FNITFDVDSKASLGNKL---LLKANVTSENNMPRTNKTEFQLELPVK---YAVYMVVTSH 932
            F +       +    +L   LL A ++ +   P + +    +ELP+     A+   +   
Sbjct: 766  FYLILSTSGISIETTELEVELLLATISEQELHPVSARARVFIELPLSIAGMAIPQQLFFS 825

Query: 933  GVSTKYLNFTASENTSRVMQHQYQVSNLGQRSLPISLVF---------------LVPVRL 977
            GV        +  +    ++++  VSN GQ    +   F               L P+++
Sbjct: 826  GVVRGERAMQSERDVGSKVKYEVTVSNQGQSLRTLGSAFLNIMWPHEIANGKWLLYPMQV 885

Query: 978  ---------NQTVIWDRPQVTFSENLSSTCHTKERLPSHSD---------------FLAE 1013
                      + +   RP +   +  S     +E  P                     AE
Sbjct: 886  ELEGGQGPGQKGLCSPRPNILHLDVDSRDRRRRELEPPEQQEPGERQEPSMSWWPVSSAE 945

Query: 1014 LRKAPVVNCSIAVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYIK--TSHNHLLIVSTAE 1071
             +K   ++C+      +    P +         + G L    +++  ++   L ++  A 
Sbjct: 946  KKKNITLDCARGTANCVVFSCPLYSFDRAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRAN 1005

Query: 1072 ILFNDSVFTLLPGQGAFVRSQTETKVEPFEVPN---PLPLIVGSSVGGLLLLALITAALY 1128
            I    S+  L+    + V       ++P  V     P  +I+ + + GLL+LAL+   L+
Sbjct: 1006 ITVKSSIKNLMLRDASTV-IPVMVYLDPMAVVAEGVPWWVILLAVLAGLLVLALLVLLLW 1064

Query: 1129 KLGFFKR 1135
            K+GFFKR
Sbjct: 1065 KMGFFKR 1071


>gi|4505111 matrilin 1, cartilage matrix protein [Homo sapiens]
          Length = 496

 Score = 93.6 bits (231), Expect = 1e-18
 Identities = 63/218 (28%), Positives = 109/218 (50%), Gaps = 19/218 (8%)

Query: 149 SDIAFLIDGSGSIIPHDFRRMKEFVSTVMEQLKKSKTL--FSLMQYSEEFRIHFTFKEFQ 206
           +D+ FLIDGS S+ P +F  +K+F+S +++ L  S  L    L+QYS   R  F    F 
Sbjct: 274 TDLVFLIDGSKSVRPENFELVKKFISQIVDTLDVSDKLAQVGLVQYSSSVRQEFPLGRFH 333

Query: 207 NNPNPRSLVKPITQLLGRTHTATGIRKVVRELFNITNGARKNAFKILVVITDGEKFGDPL 266
              + ++ V+ ++ +   T T   ++ ++   F +++GAR  A K+ +V TDG       
Sbjct: 334 TKKDIKAAVRNMSYMEKGTMTGAALKYLIDNSFTVSSGARPGAQKVGIVFTDGRS----- 388

Query: 267 GYEDVIPEADRE----GVIRYVIGVGDAFRSEKSRQELNTIASKPPRDHVFQVNNFEALK 322
             +D I +A ++    G   + +GVG+A        EL  IAS+P  +H F   +F+ + 
Sbjct: 389 --QDYINDAAKKAKDLGFKMFAVGVGNAV-----EDELREIASEPVAEHYFYTADFKTIN 441

Query: 323 TIQNQLREKIFAIEGTQTGSSSSFEHEMSQEGFSAAIT 360
            I  +L++KI  +E       S  + +   EG   A+T
Sbjct: 442 QIGKKLQKKI-CVEEDPCACESLVKFQAKVEGLLQALT 478



 Score = 70.5 bits (171), Expect = 9e-12
 Identities = 49/192 (25%), Positives = 88/192 (45%), Gaps = 13/192 (6%)

Query: 144 CPQEDSDIAFLIDGSGSIIPHDFRRMKEFVSTVMEQLK--KSKTLFSLMQYSEEFRIHFT 201
           C    +D+ F++D S S+ P +F ++K F+S V+E L    + T   ++ Y+   +  F+
Sbjct: 35  CRTRPTDLVFVVDSSRSVRPVEFEKVKVFLSQVIESLDVGPNATRVGMVNYASTVKQEFS 94

Query: 202 FKEFQNNPNPRSLVKPITQLLGRTHTATGIRKVVRELFNITNGARKNA---FKILVVITD 258
            +   +       V+ I  L   T T   I+  + + F    G R  +    K+++V+TD
Sbjct: 95  LRAHVSKAALLQAVRRIQPLSTGTMTGLAIQFAITKAFGDAEGGRSRSPDISKVVIVVTD 154

Query: 259 GEKFGDPLGYEDVIPEADREGVIRYVIGVGDAFRSEKSRQELNTIASKPPRDHVFQVNNF 318
           G         +DV   A   GV  + IGVG        +  L  IAS+P  +HV  V ++
Sbjct: 155 GRPQDS---VQDVSARARASGVELFAIGVGSV-----DKATLRQIASEPQDEHVDYVESY 206

Query: 319 EALKTIQNQLRE 330
             ++ +  + +E
Sbjct: 207 SVIEKLSRKFQE 218


>gi|55743096 collagen, type XIV, alpha 1 [Homo sapiens]
          Length = 1796

 Score = 90.9 bits (224), Expect = 6e-18
 Identities = 61/198 (30%), Positives = 97/198 (48%), Gaps = 11/198 (5%)

Query: 134  PQKFPEALRGCPQEDSDIAFLIDGSGSIIPHDFRRMKEFVSTVMEQLKK---SKTLFSLM 190
            P   P A   C    +D+ F++DGS SI   +F ++  F+ + +  L K     T  +++
Sbjct: 1016 PPTIPPAKEVCKAAKADLVFMVDGSWSIGDENFNKIISFLYSTVGALNKIGTDGTQVAMV 1075

Query: 191  QYSEEFRIHFTFKEFQNNPNPRSLVKPITQLLGRTHTATGIRKVVRELFNITNGARKNAF 250
            Q++++ R  F    ++        +K I+   G T T   I+ V   LF   +G R+   
Sbjct: 1076 QFTDDPRTEFKLNAYKTKETLLDAIKHISYKGGNTKTGKAIKYVRDTLFTAESGTRRGIP 1135

Query: 251  KILVVITDGEKFGDPLGYEDVIPEADREGVIRYVIGVGDAFRSEKSRQELNTIASKPPRD 310
            K++VVITDG    D      +  E   +G   + IGV DA  S     EL +I SKP   
Sbjct: 1136 KVIVVITDGRSQDD---VNKISREMQLDGYSIFAIGVADADYS-----ELVSIGSKPSAR 1187

Query: 311  HVFQVNNFEALKTIQNQL 328
            HVF V++F+A K I+++L
Sbjct: 1188 HVFFVDDFDAFKKIEDEL 1205



 Score = 71.2 bits (173), Expect = 5e-12
 Identities = 54/185 (29%), Positives = 83/185 (44%), Gaps = 16/185 (8%)

Query: 149 SDIAFLIDGSGSIIPHDFRRMKEFVSTVME--QLKKSKTLFSLMQYSEEFRIHFTFKEFQ 206
           +DI  L+DGS SI   +FR ++ F+  ++    +   KT   L QYS + RI +    F 
Sbjct: 157 ADIVILVDGSWSIGRFNFRLVRHFLENLVTAFDVGSEKTRIGLAQYSGDPRIEWHLNAFS 216

Query: 207 NNPNPRSLVKPITQLLGRTHTATGIRKVVRELFNITNGARKNAFKILVVITDGEKFGDPL 266
                   V+ +    G T T   +  +    F    G+R    KI ++ITDG+      
Sbjct: 217 TKDEVIEAVRNLPYKGGNTLTGLALNYIFENSFKPEAGSRTGVSKIGILITDGK------ 270

Query: 267 GYEDVIPEA---DREGVIRYVIGVGDAFRSEKSRQELNTIASKPPRDHVFQVNNFEALKT 323
             +D+IP +      GV  + IGV +A        EL  IAS+P   HV+ V  F+ + T
Sbjct: 271 SQDDIIPPSRNLRESGVELFAIGVKNA-----DVNELQEIASEPDSTHVYNVAEFDLMHT 325

Query: 324 IQNQL 328
           +   L
Sbjct: 326 VVESL 330


>gi|62548862 matrilin 2 isoform b precursor [Homo sapiens]
          Length = 937

 Score = 86.7 bits (213), Expect = 1e-16
 Identities = 64/238 (26%), Positives = 109/238 (45%), Gaps = 18/238 (7%)

Query: 102 LLACGPTVHQTCSENTYVKGLCFLFGSNLRQQPQKFPEAL--RGCPQEDSDIAFLIDGSG 159
           LL  G  V          +G     G + R  PQ    AL    C  + +D+ F+ID S 
Sbjct: 10  LLILGQIVLLPAEARERSRGRSISRGRHARTHPQT---ALLESSCENKRADLVFIIDSSR 66

Query: 160 SIIPHDFRRMKEFVSTVME--QLKKSKTLFSLMQYSEEFRIHFTFKEFQNNPNPRSLVKP 217
           S+  HD+ ++KEF+  +++   +    T   L+QY    +  F+ K F+        VK 
Sbjct: 67  SVNTHDYAKVKEFIVDILQFLDIGPDVTRVGLLQYGSTVKNEFSLKTFKRKSEVERAVKR 126

Query: 218 ITQLLGRTHTATGIRKVVRELFNITNGA---RKNAFKILVVITDGEKFGDPLGYEDVIPE 274
           +  L   T T   I+  +   F+   GA   R+N  ++++++TDG          +V  +
Sbjct: 127 MRHLSTGTMTGLAIQYALNIAFSEAEGARPLRENVPRVIMIVTDGRPQD---SVAEVAAK 183

Query: 275 ADREGVIRYVIGVGDAFRSEKSRQELNTIASKPPRDHVFQVNNFEALKTIQNQLREKI 332
           A   G++ + IGVG     +     L +I S+P  DHVF V NF  ++T+ +  ++K+
Sbjct: 184 ARDTGILIFAIGVG-----QVDFNTLKSIGSEPHEDHVFLVANFSQIETLTSVFQKKL 236



 Score = 75.1 bits (183), Expect = 4e-13
 Identities = 51/194 (26%), Positives = 90/194 (46%), Gaps = 13/194 (6%)

Query: 144 CPQEDSDIAFLIDGSGSIIPHDFRRMKEFVSTVMEQLKKS--KTLFSLMQYSEEFRIHFT 201
           C +   D+ F+IDGS S+   +F  +K+FV+ +++ L  S       L+QYS +    FT
Sbjct: 649 CTEGPIDLVFVIDGSKSLGEENFEVVKQFVTGIIDSLTISPKAARVGLLQYSTQVHTEFT 708

Query: 202 FKEFQNNPNPRSLVKPITQLLGRTHTATGIRKVVRELFNITNGARKNAFKI---LVVITD 258
            + F +  + +  V  +  +   + T   ++ +    F    GAR  + ++    +V TD
Sbjct: 709 LRNFNSAKDMKKAVAHMKYMGKGSMTGLALKHMFERSFTQGEGARPLSTRVPRAAIVFTD 768

Query: 259 GEKFGDPLGYEDVIPEADREGVIRYVIGVGDAFRSEKSRQELNTIASKPPRDHVFQVNNF 318
           G    D     +   +A   G+  Y +GVG A       +EL  IAS+P   H+F   +F
Sbjct: 769 GRAQDD---VSEWASKAKANGITMYAVGVGKAI-----EEELQEIASEPTNKHLFYAEDF 820

Query: 319 EALKTIQNQLREKI 332
             +  I  +L++ I
Sbjct: 821 STMDEISEKLKKGI 834


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.134    0.394 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 42,449,591
Number of Sequences: 37866
Number of extensions: 1883836
Number of successful extensions: 4391
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 57
Number of HSP's successfully gapped in prelim test: 19
Number of HSP's that attempted gapping in prelim test: 3919
Number of HSP's gapped (non-prelim): 189
length of query: 1152
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1039
effective length of database: 13,968,660
effective search space: 14513437740
effective search space used: 14513437740
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 68 (30.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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