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Search of human proteins with 87196347
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|87196347 zinc finger, B-box domain containing [Homo sapiens]
(800 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|87196347 zinc finger, B-box domain containing [Homo sapiens] 1597 0.0
gi|71061468 centromere protein E [Homo sapiens] 52 3e-06
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 43 0.001
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 41 0.004
gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens] 41 0.005
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 40 0.007
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 40 0.011
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa... 40 0.011
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 40 0.011
gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens] 39 0.019
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 39 0.019
gi|154354990 ankyrin repeat domain 26 [Homo sapiens] 39 0.025
gi|30794488 kinesin family member 27 [Homo sapiens] 38 0.042
gi|90819229 cutaneous T-cell lymphoma-associated antigen 1 isofo... 37 0.055
gi|55770834 centromere protein F [Homo sapiens] 37 0.072
gi|156139122 CXXC finger 6 [Homo sapiens] 37 0.095
gi|150378543 MYST histone acetyltransferase (monocytic leukemia)... 37 0.095
gi|150378463 MYST histone acetyltransferase (monocytic leukemia)... 37 0.095
gi|150378493 MYST histone acetyltransferase (monocytic leukemia)... 37 0.095
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 36 0.12
gi|149363642 coiled-coil domain containing 144A [Homo sapiens] 36 0.12
gi|87298937 centrosomal protein 110kDa [Homo sapiens] 36 0.16
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 35 0.21
gi|19913392 regulator of G-protein signalling 3 isoform 4 [Homo ... 35 0.21
gi|114155127 regulator of G-protein signalling 3 isoform 6 [Homo... 35 0.21
gi|62865656 regulator of G-protein signalling 3 isoform 5 [Homo ... 35 0.21
gi|10864075 regulator of G-protein signalling 3 isoform 2 [Homo ... 35 0.21
gi|62865651 regulator of G-protein signalling 3 isoform 1 [Homo ... 35 0.21
gi|32967605 bromodomain adjacent to zinc finger domain, 1A isofo... 35 0.21
gi|32967603 bromodomain adjacent to zinc finger domain, 1A isofo... 35 0.21
>gi|87196347 zinc finger, B-box domain containing [Homo sapiens]
Length = 800
Score = 1597 bits (4136), Expect = 0.0
Identities = 800/800 (100%), Positives = 800/800 (100%)
Query: 1 MNRKDFVVLPWGKPGNSVKLKYRNAQELRMEKVQLEFENQEMEKKLQEFRSTRNKEKEDR 60
MNRKDFVVLPWGKPGNSVKLKYRNAQELRMEKVQLEFENQEMEKKLQEFRSTRNKEKEDR
Sbjct: 1 MNRKDFVVLPWGKPGNSVKLKYRNAQELRMEKVQLEFENQEMEKKLQEFRSTRNKEKEDR 60
Query: 61 ESSEYYWKSGKVGKLVNQSYMMSQNKGNVVKFSAGKVKLKLLKEQIQEPVKPTVNYKMAN 120
ESSEYYWKSGKVGKLVNQSYMMSQNKGNVVKFSAGKVKLKLLKEQIQEPVKPTVNYKMAN
Sbjct: 61 ESSEYYWKSGKVGKLVNQSYMMSQNKGNVVKFSAGKVKLKLLKEQIQEPVKPTVNYKMAN 120
Query: 121 SSECEKPKINGKVCGQCENKAALLVCLECGEDYCSGCFAKVHQKGALKLHRTTLLQAKSQ 180
SSECEKPKINGKVCGQCENKAALLVCLECGEDYCSGCFAKVHQKGALKLHRTTLLQAKSQ
Sbjct: 121 SSECEKPKINGKVCGQCENKAALLVCLECGEDYCSGCFAKVHQKGALKLHRTTLLQAKSQ 180
Query: 181 ILFNVLDVAHQFIKDVNPDEPKEENNSTKETSKIQHKPKSVLLQRSSSEVEITTMKRAQR 240
ILFNVLDVAHQFIKDVNPDEPKEENNSTKETSKIQHKPKSVLLQRSSSEVEITTMKRAQR
Sbjct: 181 ILFNVLDVAHQFIKDVNPDEPKEENNSTKETSKIQHKPKSVLLQRSSSEVEITTMKRAQR 240
Query: 241 TKPRKSLLCEGSFDEEASAQSFQEVLSQWRTGNHDDNKKQNLHAAVKDSLEECEVQTNLK 300
TKPRKSLLCEGSFDEEASAQSFQEVLSQWRTGNHDDNKKQNLHAAVKDSLEECEVQTNLK
Sbjct: 241 TKPRKSLLCEGSFDEEASAQSFQEVLSQWRTGNHDDNKKQNLHAAVKDSLEECEVQTNLK 300
Query: 301 IWREPLNIELKEDILSYMEKLWLKKHRRTPQEQLFKMLPDTFPHPHETTGDAQCSQNEND 360
IWREPLNIELKEDILSYMEKLWLKKHRRTPQEQLFKMLPDTFPHPHETTGDAQCSQNEND
Sbjct: 301 IWREPLNIELKEDILSYMEKLWLKKHRRTPQEQLFKMLPDTFPHPHETTGDAQCSQNEND 360
Query: 361 EDSDGEETKVQHTALLLPVETLNIERPEPSLKIVELDDTYEEEFEEAENIVPYKVKLADA 420
EDSDGEETKVQHTALLLPVETLNIERPEPSLKIVELDDTYEEEFEEAENIVPYKVKLADA
Sbjct: 361 EDSDGEETKVQHTALLLPVETLNIERPEPSLKIVELDDTYEEEFEEAENIVPYKVKLADA 420
Query: 421 DSQRSCAFHDCQKNSFPYENGIHQHHVFDKGKRDFLNLCLRNSSTYYKDNSKAETSNTDF 480
DSQRSCAFHDCQKNSFPYENGIHQHHVFDKGKRDFLNLCLRNSSTYYKDNSKAETSNTDF
Sbjct: 421 DSQRSCAFHDCQKNSFPYENGIHQHHVFDKGKRDFLNLCLRNSSTYYKDNSKAETSNTDF 480
Query: 481 DNIVDPDVYSSDIEKIEESTSFERNLKEKNIGLESNQKSDDSCVSLESKDTLLGRDLEKA 540
DNIVDPDVYSSDIEKIEESTSFERNLKEKNIGLESNQKSDDSCVSLESKDTLLGRDLEKA
Sbjct: 481 DNIVDPDVYSSDIEKIEESTSFERNLKEKNIGLESNQKSDDSCVSLESKDTLLGRDLEKA 540
Query: 541 PIEEKLSQDIKESLELSNLYKRPSFEESKTTKSSLLLQEIACRSKPITKQYQGLERFFIF 600
PIEEKLSQDIKESLELSNLYKRPSFEESKTTKSSLLLQEIACRSKPITKQYQGLERFFIF
Sbjct: 541 PIEEKLSQDIKESLELSNLYKRPSFEESKTTKSSLLLQEIACRSKPITKQYQGLERFFIF 600
Query: 601 DTNERLNLLPSHRLECNNSSTRITLAGQKSQRPSTANFPLSNSVKESSSCLSSSHPRSRS 660
DTNERLNLLPSHRLECNNSSTRITLAGQKSQRPSTANFPLSNSVKESSSCLSSSHPRSRS
Sbjct: 601 DTNERLNLLPSHRLECNNSSTRITLAGQKSQRPSTANFPLSNSVKESSSCLSSSHPRSRS 660
Query: 661 AAAQSSSRAASEISEIEYIDITDQNELSLDDTTDQHTLDNLEKELQVLRSLADTSEKLYS 720
AAAQSSSRAASEISEIEYIDITDQNELSLDDTTDQHTLDNLEKELQVLRSLADTSEKLYS
Sbjct: 661 AAAQSSSRAASEISEIEYIDITDQNELSLDDTTDQHTLDNLEKELQVLRSLADTSEKLYS 720
Query: 721 LTSEEFPDFSSQSLNISQISTDFLKTSHVRGPCGVEELSCSGRDTKIQSLLSLSESSTDE 780
LTSEEFPDFSSQSLNISQISTDFLKTSHVRGPCGVEELSCSGRDTKIQSLLSLSESSTDE
Sbjct: 721 LTSEEFPDFSSQSLNISQISTDFLKTSHVRGPCGVEELSCSGRDTKIQSLLSLSESSTDE 780
Query: 781 EEEDFLNKQHVITLPWSKST 800
EEEDFLNKQHVITLPWSKST
Sbjct: 781 EEEDFLNKQHVITLPWSKST 800
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 51.6 bits (122), Expect = 3e-06
Identities = 155/784 (19%), Positives = 306/784 (39%), Gaps = 142/784 (18%)
Query: 18 VKLKYRNAQELRMEKVQLEFENQEMEKKLQEFRSTRNKEKEDRESSEYY-WKSGKVGKLV 76
+K K + QE + + + ++ E EM+KK+ E + +N+ K + E+ + ++ + +
Sbjct: 1129 LKEKSQQLQEKQQQLLNVQEEMSEMQKKINEIENLKNELKNKELTLEHMETERLELAQKL 1188
Query: 77 NQSYMMSQNKGNVVKFSAGKVKLKLLKEQIQEPVKPTVNYKMANSSECEKPKINGKVCGQ 136
N++Y + ++ K + K+LKE + S E E+ + G +
Sbjct: 1189 NENY---EEVKSITK------ERKVLKE-------------LQKSFETERDHLRGYI--- 1223
Query: 137 CENKAALLVCLECGEDYCSGCFAKVHQKGALKLHRTTLLQAKSQILFNVLDVAHQFIKDV 196
E +A L E E + K HQ+ +L R+ + I L+ +H +++
Sbjct: 1224 REIEATGLQTKE--ELKIAHIHLKEHQETIDELRRSVSEKTAQIINTQDLEKSHTKLQEE 1281
Query: 197 NP--DEPKEENNSTKETSKIQHKPKSV-LLQRSSSEVEITTMKRAQRTKPRKSLLCEGSF 253
P E +E + KE S+ Q + LL S+ + TT+ R + + R +
Sbjct: 1282 IPVLHEEQELLPNVKEVSETQETMNELELLTEQSTTKDSTTLARIEMERLRLN------- 1334
Query: 254 DEEASAQSFQEVLSQWRTGNHDDNKKQNLHAAVKDSLEECEVQTNLKIWREPLNI---EL 310
+ FQE ++ + + K+ + NLK +E L + +L
Sbjct: 1335 ------EKFQE-------------SQEEIKSLTKE-------RDNLKTIKEALEVKHDQL 1368
Query: 311 KEDILSYMEKLWLKKHRRTPQEQLFKMLPDTFPHPHETTGDAQCSQNENDEDSDGEETKV 370
KE I + K+ + ++ QEQ M +ETT S+ E+ K
Sbjct: 1369 KEHIRETLAKI---QESQSKQEQSLNMK----EKDNETTKIV----------SEMEQFKP 1411
Query: 371 QHTALLLPVETLNIERPEPSLKIVELDDTYEEEFEEAENIVPYKVKLADADSQRSCAFHD 430
+ +ALL + IE S ++ E D + +E +++ + L Q +
Sbjct: 1412 KDSALL----RIEIEMLGLSKRLQESHDEMKSVAKEKDDLQRLQEVLQSESDQLKENIKE 1467
Query: 431 CQKNSFPYENGIHQHHVFDKGKRDFLNLCLRNSSTYYKDNS----KAETSNTDFDNIVDP 486
E + H K + + +N N S + S + E N N +
Sbjct: 1468 IVAKHLETEEELKVAHCCLKEQEETINELRVNLSEKETEISTIQKQLEAINDKLQNKIQE 1527
Query: 487 DVYSSDIEKIEESTSFERNLKEKNIGLESNQKSDDSCVSLESKDTLLGRDLEKAPIEEKL 546
+ I++ + + + E E + D + S+ESK L L+++ +E++
Sbjct: 1528 IYEKEEQFNIKQISEVQEKVNELKQFKEHRKAKDSALQSIESKMLELTNRLQES--QEEI 1585
Query: 547 SQDIKESLELSNLYKRPSFEESKTTKSSLLLQEIACRSKPI-TKQYQGLERFFIFDTNER 605
IKE E+ + + E + +++ +EI + K K+YQ L+ + +T E+
Sbjct: 1586 QIMIKEKEEMKRVQEALQIERDQLKENT---KEIVAKMKESQEKEYQFLKMTAVNETQEK 1642
Query: 606 LNLLPSHRLECNNSSTRITLAGQKSQRPSTANFPLSNSVKESSSCLSSSHPRSRSAAAQS 665
+ E + + + T N L+ + E+ + S +
Sbjct: 1643 M-------CEIEHLKEQFETQKLNLENIETENIRLTQILHENLEEMRS------VTKERD 1689
Query: 666 SSRAASEISEIEYIDITDQNELSLDDTTDQHTLDNLEKELQV------LRSLADTSEKLY 719
R+ E ++E DQ + +L +T + +LEK+ ++ L+ +T +KL
Sbjct: 1690 DLRSVEETLKVE----RDQLKENLRETITR----DLEKQEELKIVHMHLKEHQETIDKLR 1741
Query: 720 SLTSEEFPDFSSQSLNISQISTDFLKTSHVRGPCGVEELSCSGRDTKIQSLLSLSESSTD 779
+ SE+ + S+ ++ S D LK +D KIQ L ++
Sbjct: 1742 GIVSEKTNEISNMQKDLEH-SNDALK----------------AQDLKIQEELRIAHMHLK 1784
Query: 780 EEEE 783
E++E
Sbjct: 1785 EQQE 1788
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 42.7 bits (99), Expect = 0.001
Identities = 145/700 (20%), Positives = 267/700 (38%), Gaps = 90/700 (12%)
Query: 26 QELRMEKVQLEFENQEMEKKLQEFRSTRNKEKEDRESSEYYWKSGKVGKLVNQSYMMSQN 85
QELR ++ Q E E++K L+E T+N E + ++ + + + + +L Q +
Sbjct: 1166 QELRTKREQ---EVAELKKALEE--ETKNHEAQIQDMRQRH--ATALEELSEQLEQAKRF 1218
Query: 86 KGNVVKFSAGKVKLKLLKEQIQEPVKPTVNYKMANSSECEKPKINGKVCGQCENKAALLV 145
K N+ K G L+ +++ VK V ++ SE ++ K++ +V
Sbjct: 1219 KANLEKNKQG---LETDNKELACEVK--VLQQVKAESEHKRKKLDAQV------------ 1261
Query: 146 CLECGEDYCSGCFAKVHQKGALKLHRTTLLQAKSQILFNVLDVAHQFIKDVNPDEPKEEN 205
AKV + L++ L K+ L N LD +++ K
Sbjct: 1262 ---------QELHAKVSEGDRLRVE----LAEKASKLQNELDNVSTLLEEAEKKGIKFAK 1308
Query: 206 NSTKETSKIQHKPKSVLLQRSSSEVEITTMKRAQRTKPRKSLLCEGSFDEEASAQSFQEV 265
++ S++Q + LLQ + + ++ R ++ + K+ L E +EE + ++ ++
Sbjct: 1309 DAASLESQLQDTQE--LLQEETRQ-KLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQ 1365
Query: 266 LSQWRTGNHDDNKKQNLHAAVKDSLEECEVQTNLKIWREPLNIELKEDILSYMEKLWLKK 325
+ ++ D KK + +SLE E + L E L+ L+E L+Y + L+K
Sbjct: 1366 VLALQSQLADTKKKVDDDLGTIESLE--EAKKKLLKDAEALSQRLEEKALAYDK---LEK 1420
Query: 326 HRRTPQEQLFKMLPDTFPHPHETTGDAQCSQNENDEDSDGEETKVQHTALLLPVETLNIE 385
+ Q++L + D H + + + Q + D+ E K + E
Sbjct: 1421 TKNRLQQELDDLTVD-LDHQRQVASNLEKKQKKFDQLL--AEEKSISARYAEERDRAEAE 1477
Query: 386 RPEPSLKIVELDDTYEEEFEEAENIVPYKVKL-ADADSQRSCA------FHDCQKNSFPY 438
E K + L EE E E +L AD + S H+ +K+
Sbjct: 1478 AREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRAL 1537
Query: 439 ENGIHQHHVFDKGKRDFLNLCLRNSSTYYKDNSKAETSNTDFDNIVDPDVYSSDIEKIEE 498
E + + + D L ++ + N +A + + D+ + D + E+
Sbjct: 1538 EQQVEEMRTQLEELEDELQ-ATEDAKLRLEVNMQAMKAQ------FERDLQTRDEQNEEK 1590
Query: 499 STSFERNLKEKNIGLESNQKSDDSCVSLESKDTLLGRDLEKAPIEEKLSQDIKESLELSN 558
+ ++E LE +K V+ + K + +DLE A IE + +L
Sbjct: 1591 KRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLE-AQIEAANKARDEVIKQLRK 1649
Query: 559 LYKRPSFEESKTTKSSLLLQEIACRSKPITKQYQGLERFFIFDTNERLNLLPSHRLECNN 618
L + + + ++ EI +SK K+ + LE + E L S R +
Sbjct: 1650 LQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEE---LASSERARRHA 1706
Query: 619 SSTRITLAGQKSQRPSTANFPLSNSVKESSSCLSSSHPRSRSAAAQSSSRAASEISEIEY 678
R LA + ++NS S+ L R + AQ E S +E
Sbjct: 1707 EQERDELADE-----------ITNSASGKSALLDEKR-RLEARIAQLEEELEEEQSNMEL 1754
Query: 679 IDITDQNELSLDDTTDQHTL--DNLEKELQVLRSLADTSE 716
L+D + TL D L EL RS A S+
Sbjct: 1755 ----------LNDRFRKTTLQVDTLNAELAAERSAAQKSD 1784
Score = 38.1 bits (87), Expect = 0.033
Identities = 157/809 (19%), Positives = 296/809 (36%), Gaps = 99/809 (12%)
Query: 26 QELRMEKVQLEFENQEMEKK---LQEFRSTRNKEK---EDR------ESSEYYWKSGKVG 73
Q+L++EKV E + ++ME++ L++ S KEK EDR + +E K+ +
Sbjct: 967 QKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLA 1026
Query: 74 KLVNQSYMMSQN------KGNVVKFSAGKVKLKL------LKEQIQEPVKPTVNYKM--- 118
K+ N+ +M + K + K K KL L++QI E K+
Sbjct: 1027 KIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLA 1086
Query: 119 ANSSECEKPKINGKVCGQCENKAALLV------CLECGEDYCSGCFAKVHQKGALKLHR- 171
E + G +N A +V E ED+ S K + A K R
Sbjct: 1087 KKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFES---EKASRNKAEKQKRD 1143
Query: 172 -TTLLQAKSQILFNVLD--VAHQFIKDVNPDEPKEENNSTKETSKIQHKPKSVLLQRSSS 228
+ L+A L + LD A Q ++ E E + +E +K + QR ++
Sbjct: 1144 LSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHAT 1203
Query: 229 EVEITT--MKRAQRTKPRKSLLCEGSFDEEASAQSFQEVLSQWRTGNHDDNKK-----QN 281
+E + +++A+R K +G + +VL Q + + KK Q
Sbjct: 1204 ALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQE 1263
Query: 282 LHAAVKDSLEECEVQTNLKIWREPLNIELKEDILSYMEKLWLKKHRRTPQEQLFKMLPDT 341
LHA V + + V+ K + ++ +L EK +K + L L DT
Sbjct: 1264 LHAKVSEG-DRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAK--DAASLESQLQDT 1320
Query: 342 FPHPHETTGD--------AQCSQNENDEDSDGEETKVQHTALLLPVETLNIERPEPSLKI 393
E T Q + +N EE + L V L + + K+
Sbjct: 1321 QELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKV 1380
Query: 394 VELDDTYEEEFEEAENIVPYKVKLADADSQRSCAFHDCQKNSFPYENGI--------HQH 445
+ T E E + ++ L+ +++ A+ +K + + HQ
Sbjct: 1381 DDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQR 1440
Query: 446 HV---FDKGKRDFLNLCLRN---SSTYYKDNSKAETSNTDFDNIVDPDVYSSDIEKIEES 499
V +K ++ F L S+ Y ++ +AE + + + + E +E
Sbjct: 1441 QVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALE-EALEAK 1499
Query: 500 TSFERNLKEKNIGLESNQKSDD-----------SCVSLESKDTLLGRDLEKAPIEEKLSQ 548
FER K+ +E S D S +LE + + LE+ E + ++
Sbjct: 1500 EEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATE 1559
Query: 549 DIKESLELSNLYKRPSFEESKTTKSSLLLQEIACRSKPITKQYQGLERFFIFDTNERLNL 608
D K LE++ + FE T+ ++ + + + KQ + LE + +R
Sbjct: 1560 DAKLRLEVNMQAMKAQFERDLQTRD----EQNEEKKRLLIKQVRELEAELEDERKQRALA 1615
Query: 609 LPSHR---LECNNSSTRITLAGQKSQRPSTANFPLSNSVKESSSCLSSSHPRSRSAAAQS 665
+ S + ++ + +I A + L +K+ L + SR
Sbjct: 1616 VASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEAR-ASRDEIFAQ 1674
Query: 666 SSRAASEISEIEYIDITDQNELSLDDTTDQHT-------LDNLEKELQVLRSLADTSEKL 718
S + ++ +E + Q EL+ + +H D + +L D +L
Sbjct: 1675 SKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRL 1734
Query: 719 YSLTSEEFPDFSSQSLNISQISTDFLKTS 747
+ ++ + + N+ ++ F KT+
Sbjct: 1735 EARIAQLEEELEEEQSNMELLNDRFRKTT 1763
Score = 32.3 bits (72), Expect = 1.8
Identities = 67/319 (21%), Positives = 126/319 (39%), Gaps = 43/319 (13%)
Query: 494 EKIEESTSFERNLKEKNIGLESNQKSDDSC-------VSLESKDTLLGRDLEKAPIEEKL 546
E++E++ F+ NL++ GLE++ K + +C V ES+ D + + K+
Sbjct: 1210 EQLEQAKRFKANLEKNKQGLETDNK-ELACEVKVLQQVKAESEHKRKKLDAQVQELHAKV 1268
Query: 547 SQDIKESLELSNLYKRPSFEESKTTKSSLLLQEIACRSKPITKQYQGLERFFIFDTNERL 606
S+ + +EL+ ++ S +++ S LL+E + K LE + DT E
Sbjct: 1269 SEGDRLRVELA---EKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLES-QLQDTQE-- 1322
Query: 607 NLLPSHRLECNNSSTRITLAGQKSQRPSTANFPLSNSVKESSSCLSSSHPRSRSAAAQSS 666
LL + N S+RI ++ + + +E+ L +S A +
Sbjct: 1323 -LLQEETRQKLNLSSRI----RQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTK 1377
Query: 667 SRAASEISEIEYIDITDQNELSLDDTTDQHTLDNLEKELQVLRSLADTSEKLYSLTSEEF 726
+ ++ IE ++ + L + L + L+ D EK + +E
Sbjct: 1378 KKVDDDLGTIESLEEAKKKLLK--------DAEALSQRLEEKALAYDKLEKTKNRLQQEL 1429
Query: 727 PDFSSQSLNISQISTDFLKTSHVRGPCGVEELSCSGR---------------DTKIQSLL 771
D + + Q++++ K EE S S R +TK SL
Sbjct: 1430 DDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLA 1489
Query: 772 -SLSESSTDEEEEDFLNKQ 789
+L E+ +EE + NKQ
Sbjct: 1490 RALEEALEAKEEFERQNKQ 1508
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin
(with transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 41.2 bits (95), Expect = 0.004
Identities = 100/496 (20%), Positives = 192/496 (38%), Gaps = 46/496 (9%)
Query: 255 EEASAQSFQEVLSQWRTGNHDDNKKQNLHAAVKDS-----LEECEVQTNLKIWREPLNIE 309
++ Q E L + R + KK LHA K + +EE + Q + EP + E
Sbjct: 71 KDVQLQQKDEALQEERKAADNKIKKLKLHAKAKLTSLNKYIEEMKAQGGTVLPTEPQSEE 130
Query: 310 L--KEDILSYMEKLWLKK--HRRTPQEQLFKMLPDTFPHPHETTGDAQCSQNENDEDSDG 365
K D S E++ ++K H+ +E+L L ++ E
Sbjct: 131 QLSKHDKSSTEEEMEIEKIKHKLQEKEELISTLQAQLTQAQAEQPAQSSTEMEEFVMMKQ 190
Query: 366 EETKVQHTALLLPVETLNIERPEPSLKIV-ELDDTYEEEFEEAENIVPYKVKLADADSQR 424
+ + + L + + + + ++V E D +E + E+ + V AD +++
Sbjct: 191 QLQEKEEFISTLQAQLSQTQAEQAAQQVVREKDARFETQVRLHEDELLQLVTQADVETEM 250
Query: 425 SCAFHDCQKNSFPYENG-IHQHHVFDKGKRDFLNLCLRNSSTYYKDNSKAETSNTDFDNI 483
Q+ +E + + V D +++ L + + + + E + N
Sbjct: 251 QQKLRVLQRKLEEHEESLVGRAQVVDLLQQE-LTAAEQRNQILSQQLQQMEAEHNTLRNT 309
Query: 484 VDPDVYSS-------DIEKIEESTSFERNLKEKNIGLESNQKSDDSCVSLESKDTLLGRD 536
V+ + S ++E E SF +E + LE +++ + LES+ + L +
Sbjct: 310 VETEREESKILLEKMELEVAERKLSFHNLQEEMHHLLEQFEQAGQAQAELESRYSALEQK 369
Query: 537 LEKAPIEEKLSQDIKESLELSNLYKRPSFEESKTTKSSLLLQ--EIACRSKPITKQYQGL 594
KA +EEK S + SL+ + + + + K S LL E A +S +Q +
Sbjct: 370 -HKAEMEEKTSHIL--SLQKTGQELQSACDALKDQNSKLLQDKNEQAVQSAQTIQQLEDQ 426
Query: 595 ERFFIFDTNERLNLLPSHRLECNNSSTRITLAGQKSQRPSTANFP-LSNSVKESSS---- 649
+ + ++ LN LP + E + ++ + + +Q + N L V E +
Sbjct: 427 LQQKSKEISQFLNRLPLQQHETASQTSFPDVYNEGTQAVTEENIASLQKRVVELENEKGA 486
Query: 650 -CLSSSHPRSRSA-------------AAQSSSRAASEISEIEYIDITDQNELSLDDTTD- 694
LSS A A + A E+SEI +DI ++ S +++
Sbjct: 487 LLLSSIELEELKAENEKLSSQITLLEAQNRTGEADREVSEISIVDIANKRSSSAEESGQD 546
Query: 695 --QHTLDNLEKELQVL 708
++T KEL VL
Sbjct: 547 VLENTFSQKHKELSVL 562
Score = 34.3 bits (77), Expect = 0.47
Identities = 107/592 (18%), Positives = 214/592 (36%), Gaps = 58/592 (9%)
Query: 202 KEENNSTKETSKIQHKPKSVLLQRSSSEVEITTMKRAQRTKPRKSLLCEGSFDEEASAQS 261
K+E S KE+ K Q K K L+R + E +K + + + L E +
Sbjct: 2102 KKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGE 2161
Query: 262 FQEVLSQWRTGNHDDNKKQNLHAAVKDSLEECEVQTNLKIWREPLNIELKEDILSYMEKL 321
Q L+ + ++NL + V + ++L+ R+ + E K+ + + +
Sbjct: 2162 IQVTLN--KKDKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAI 2219
Query: 322 WLKKHRRTPQEQLFKMLPDTFPHPHETTGDAQCSQNENDEDSDGEETKVQHTALLLP--V 379
K+ +E +L D + + + + + D E+K Q L
Sbjct: 2220 QSKEEEIRLKEDNCSVLKDQLRQMSIHMEELKINISRLEHDKQIWESKAQTEVQLQQKVC 2279
Query: 380 ETLNIERPEPSLKIVELDDTYEEEFEEAENIVPYKVKLADADSQRSCAFHDCQKNSFPYE 439
+TL E E ++ E Y E + L D + S + C++ E
Sbjct: 2280 DTLQGENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLE 2339
Query: 440 NGIHQHHVFDKGKRDFLNLCLRNSSTYYKDNSKAETSNTDFDNIVDPDVYSSDIEKIEES 499
I Q +A+ N+ F + +D++ E
Sbjct: 2340 GIIRQ--------------------------QEADIQNSKFSY----EQLETDLQASREL 2369
Query: 500 TS---FERNLKEKNIGLESNQKSDDSCVSLESKDTLLGRDLEKAPIEEKLSQDIKESLEL 556
TS E N+KE+ I S + + + + D E +E LSQ+ +E++ L
Sbjct: 2370 TSRLHEEINMKEQKI--ISLLSGKEEAIQVAIAELRQQHDKEIKELENLLSQEEEENIVL 2427
Query: 557 SNLYKRPSFEESKTTKSSLLLQEIACRSKPITKQYQGLERFFIFDT---NERLNLLPSHR 613
K+ K++ L++ + K +Q L+ F + N+R ++ ++
Sbjct: 2428 EEENKK------AVDKTNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQ 2481
Query: 614 LECNNSSTRITLAGQKSQRPSTANFPLSNSVKESSSCLSSSHPRSRSAAAQSSSRAASEI 673
+ I Q Q + N L ++ S + + + A+ + ++
Sbjct: 2482 QLEERHLSIILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAE-LIQYREDL 2540
Query: 674 SEIEYIDITDQNELSLDDTTDQHTLDN----LEKELQVLRSLADTSEKLYSLTSEEFPDF 729
+++ I + Q +L L+N LE++L+ + + ++ EE D
Sbjct: 2541 NQVITIKDSQQKQLLEVQLQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDL 2600
Query: 730 S----SQSLNISQISTDFLKTSHVRGPCGVEELSCSGRDTKIQSLLSLSESS 777
S S ++ISQ+ T + G G+ ++ ++ L +L SS
Sbjct: 2601 SKEIESLKVSISQL-TRQVTALQEEGTLGLYHAQLKVKEEEVHRLSALFSSS 2651
>gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens]
Length = 1979
Score = 40.8 bits (94), Expect = 0.005
Identities = 148/771 (19%), Positives = 277/771 (35%), Gaps = 122/771 (15%)
Query: 23 RNAQELRMEKVQLEFENQEMEKKLQEFRSTRNKEKEDRESSEYYWKSGKVGKLVNQSYMM 82
+ Q L++EKV+ + +++E K+++ + + DR+ + + +N
Sbjct: 292 KTIQVLQIEKVESTKKMEQLEDKIKDINKKLSSAENDRDILR------REQEQLNVEKRQ 345
Query: 83 SQNKGNVVKFSAGKVKLKLLKEQIQEPVKPTVNYKMANSSECEKPKINGKVCGQCENKAA 142
+ +K K++ +K+ K + +A S+ E+ + EN+
Sbjct: 346 IMEECENLKLECSKLQPSAVKQSDTMTEKERI---LAQSASVEEVFRLQQALSDAENEIM 402
Query: 143 LLVCLECGEDYCSGCFAKVHQKGALKLHRTTLLQAKSQILFNVLDVAHQF-------IKD 195
L L + L+ ++ L Q K ++ ++L + +++ +D
Sbjct: 403 RLSSLNQDNSLAEDNLKLKMRIEVLEKEKSLLSQEKEELQMSLLKLNNEYEVIKSTATRD 462
Query: 196 VNPDEPKEENNSTKETSKIQHKPKSVLLQRSSSEVEITTMKRAQRTKPRKSLLCEGSFDE 255
++ D + E +K Q +S+ ++ + EI + R + + +L + +
Sbjct: 463 ISLDSELHDLRLNLE-AKEQELNQSI-SEKETLIAEIEELDRQNQEATKHMILIKDQLSK 520
Query: 256 EASAQSFQEVLSQWRTGNHDDNKK-QNLHAAVKDSLEECEVQTNLKIWRE---------- 304
+ + ++S+ + +D+ K+ L D +E +VQ I E
Sbjct: 521 QQN--EGDSIISKLKQDLNDEKKRVHQLEDDKMDITKELDVQKEKLIQSEVALNDLHLTK 578
Query: 305 ------------PLNIELKEDILSYMEKLWLKKHRRTPQEQLFKMLPDTFPHPHETTGDA 352
LN + ++ E L LK+H R +E+L ++ +E
Sbjct: 579 QKLEDKVENLVDQLNKSQESNVSIQKENLELKEHIRQNEEELSRI-------RNELMQSL 631
Query: 353 QCSQNENDEDSDGEETKVQHTALLLPVETLNIERPEPSLKIVELDDTYEEEFEEAENIVP 412
N N +D+ +E + + L + L E+ +LK V D E E
Sbjct: 632 NQDSNSNFKDTLLKEREAEVRNLKQNLSEL--EQLNENLKKVAFDVKMENE--------- 680
Query: 413 YKVKLADADSQRSCAFHDCQKNSFPYE-NGIHQHHVFDKGKRDFLNLCLRNSSTYYKDNS 471
K+ LA D + N E N I + +KG+ + LC + N
Sbjct: 681 -KLVLACEDVRHQLEECLAGNNQLSLEKNTIVETLKMEKGEIE-AELCWAKKRLLEEANK 738
Query: 472 KAETSNTDFDNIVDPDVYSSDIEKIEESTSFERNLKEKNIGLES------NQKSDDSCVS 525
EK E S RNL + LE NQK D
Sbjct: 739 ---------------------YEKTIEELSNARNLNTSALQLEHEHLIKLNQKKDMEIAE 777
Query: 526 LESKDTLLGRDLEKAPIEEKLSQDIKESLELSNLY-KRPSFEESKTTKSSLLLQEI---- 580
L K + D + ++ LS ++E +L+ L K+ F E +SS L +E+
Sbjct: 778 L--KKNIEQMDTDHKETKDVLSSSLEEQKQLTQLINKKEIFIEKLKERSSKLQEELDKYS 835
Query: 581 -ACRSKPITKQYQGLERFFIFDTNERLNLLPS--HRLECNNSST----------RITLAG 627
A R I +Q + + E N L RL S T +T
Sbjct: 836 QALRKNEILRQTIEEKDRSLGSMKEENNHLQEELERLREEQSRTAPVADPKTLDSVTELA 895
Query: 628 QKSQRPSTANFPLSNSVKESSSCLSSSHPRSRSAAAQSSSRAASEISEIEYIDITDQNEL 687
+ + +T L +K + + +S+ QS E+ E Y Q+E
Sbjct: 896 SEVSQLNTIKEHLEEEIKHHQKIIEDQN-QSKMQLLQSLQEQKKEMDEFRY-----QHE- 948
Query: 688 SLDDTTDQHTLDNLEKELQVLRSLADTSEKLYSLTSEEFPDFSSQSLNISQ 738
HT LEK+ + ++SL T E++ + EE D + + +I Q
Sbjct: 949 ---QMNATHTQLFLEKD-EEIKSLQKTIEQIKTQLHEERQDIQTDNSDIFQ 995
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 40.4 bits (93), Expect = 0.007
Identities = 68/340 (20%), Positives = 128/340 (37%), Gaps = 10/340 (2%)
Query: 450 KGKRDFLNLCLRNSSTYYKDNSKAETSNTDFDNIVDPDVYSSDIEKIEESTSFERNLKEK 509
KGK D + +SS + +++ ++D ++ D D SD +S S + +
Sbjct: 544 KGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSD 603
Query: 510 NIGLESNQKSDDSCVSLESKDTLLGRDLEKAPIEEKL-SQDIKESLELSNLYKRPSFEES 568
+ + S DS S +SK + + + + K S D S N S S
Sbjct: 604 SSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSS 663
Query: 569 KTTKSSLLLQEIACRSKPITKQYQGLERFFIFDTNERLNLLPSHRLECNNSSTRITLAGQ 628
++ SS + S + D+++ N S + ++SS +
Sbjct: 664 NSSDSS-----DSSDSSDSSSSSDSSNSSDSSDSSDSSN--SSESSDSSDSSDSDSSDSS 716
Query: 629 KSQRPSTANFPLSNSVKESSSCLSS-SHPRSRSAAAQSSSRAASEISEIEYIDITDQNEL 687
S ++++ SNS S S SS S S S+ + SS ++ + + D +D ++
Sbjct: 717 DSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDS 776
Query: 688 SLDDTTDQHTLDNLEKELQVLRSLADTSEKLYSLTSEEFPDFSSQSLNISQISTDFLKTS 747
S + + + + +D+S S S + D S + + S S+D +S
Sbjct: 777 SDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSS 836
Query: 748 HVRGPCGVEELSCSGRDTKIQSLLSLSESSTDEEEEDFLN 787
+ + S G D+ + S SS + D N
Sbjct: 837 NSSDSSDSSD-SSDGSDSDSSNRSDSSNSSDSSDSSDSSN 875
Score = 40.0 bits (92), Expect = 0.009
Identities = 64/328 (19%), Positives = 124/328 (37%), Gaps = 10/328 (3%)
Query: 462 NSSTYYKDNSKAETSNTDFDNIVDPDVYSSDIEKIEESTSFERNLKEKNIGLESNQKSDD 521
+ S+ D+S + +S++D N D S+ + + S S + + ++ S D
Sbjct: 710 SDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSD 769
Query: 522 SCVSLESKDTLLGRDLEKAPIEEKLSQDIKESLELSNLYKRPSFEESKTTKSSLLLQEIA 581
S S +S D+ D + S D S + SN S + S ++ S +
Sbjct: 770 SSDSSDSSDSSNSSDSNDSSNSSD-SSDSSNSSDSSN--SSDSSDSSDSSDSDSSNSSDS 826
Query: 582 CRSKPITKQYQGLERFFIFDTNERLNLLPSHRLECNNSS--TRITLAGQKSQRPSTANFP 639
S + + D+++ + S+R + +NSS + + + S +++
Sbjct: 827 SNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSN 886
Query: 640 LSNSVKESSSCLSSSHPRSRSAAAQSSSRAASEISEIEYIDITDQNELSLDDTTDQHTLD 699
S++ +SS +SS S ++ S S +S S+ + N S D + + D
Sbjct: 887 ESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSD 946
Query: 700 NLEKELQVLRSLADTSEKLYSLTSEEFPDFSSQSLNISQISTDFLKTSHVRGPCGVEELS 759
+ + + +D+S S S + D +S + S S+D +S + S
Sbjct: 947 SSDSS-----NSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSS 1001
Query: 760 CSGRDTKIQSLLSLSESSTDEEEEDFLN 787
S + S SS D N
Sbjct: 1002 NSSDSSDSSDSSDSSNSSDSSNSSDSSN 1029
Score = 38.9 bits (89), Expect = 0.019
Identities = 71/368 (19%), Positives = 134/368 (36%), Gaps = 15/368 (4%)
Query: 418 ADADSQRSCAFHDCQKNSFPYENGIHQHHVFDKGKRDFLNLCLRNSSTYYKDNSKAETSN 477
+D+DS S D +S ++ + D N + S+ D+S + S+
Sbjct: 724 SDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSS 783
Query: 478 TDFDNIVDPDVYSSDIEKIEESTSFERNLKEKNIGLESNQKSDDSCVSLESKDTLLGRDL 537
D+ D SSD +S++ + + + S DS S +S D+ D
Sbjct: 784 DSNDSSNSSD--SSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDS 841
Query: 538 EKAPIEEKLSQDIKESLELSNLYKRPSFEESKTTKSSLLLQEIACRSKPITKQYQGLERF 597
S D + + + + S S ++ SS + S + E
Sbjct: 842 SD-------SSDSSDGSDSDSSNRSDSSNSSDSSDSS-----DSSNSSDSSDSSDSNESS 889
Query: 598 FIFDTNERLNLLPSHRLECNNSSTRITLAGQKSQRPSTANFPLSNSVKESSSCLSSSHPR 657
D+++ N S + +NSS + S+ + SNS S+S SS
Sbjct: 890 NSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSD 949
Query: 658 SRSAAAQSSSRAASEISEIEYIDITDQNELSLDDTTDQHTLDNLEKELQVLRSLADTSEK 717
S +++ S+S +S S+ + +D ++ S + + + + + +D+S+
Sbjct: 950 SSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDS 1009
Query: 718 LYSLTSEEFPDFSSQS-LNISQISTDFLKTSHVRGPCGVEELSCSGRDTKIQSLLSLSES 776
S S D S+ S + S S+D +S + S S + S+S
Sbjct: 1010 SDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDS 1069
Query: 777 STDEEEED 784
S + D
Sbjct: 1070 SDSSDSSD 1077
Score = 30.4 bits (67), Expect = 6.8
Identities = 24/102 (23%), Positives = 48/102 (47%), Gaps = 1/102 (0%)
Query: 642 NSVKESSSCLSSSHPRSRSAAAQSS-SRAASEISEIEYIDITDQNELSLDDTTDQHTLDN 700
N+ + + S +S S+ + SS S +S+ S+ D +D N S D++D + D+
Sbjct: 531 NNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDS 590
Query: 701 LEKELQVLRSLADTSEKLYSLTSEEFPDFSSQSLNISQISTD 742
+ + + +D+S+ S S + D S + S+ +D
Sbjct: 591 SDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESD 632
>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
sapiens]
Length = 1938
Score = 39.7 bits (91), Expect = 0.011
Identities = 104/546 (19%), Positives = 217/546 (39%), Gaps = 56/546 (10%)
Query: 200 EPKEENNSTKETSKIQHKPKSVLLQRSSSEVEITTMKRAQRTKPRKSLLCEGSFDEEASA 259
E +EE NS K + K L+R ++E+T K + ++ + + EE +A
Sbjct: 931 EEEEEMNSELVAKKRNLEDKCSSLKRDIDDLELTLTKVEKEKHATENKV--KNLSEEMTA 988
Query: 260 QSFQEVLSQWRTGNHDDNKKQNLHAAVKDSLEECEVQTNLKIWREPLNIELKEDILSYME 319
+E +S+ +K++L A + +L++ +V+ + +N +L++
Sbjct: 989 --LEENISKL------TKEKKSLQEAHQQTLDDLQVEEDKVNGLIKINAKLEQQTDDLEG 1040
Query: 320 KLWLKKHRRTPQEQLFKMLPDTFPHPHETTGDAQCSQNENDEDSDGEETKVQHTALLLPV 379
L +K R E+ + L E+ D + + + +E +E ++ + L +
Sbjct: 1041 SLEQEKKLRADLERAKRKLEGDLKMSQESIMDLENDKQQIEEKLKKKEFEL--SQLQAKI 1098
Query: 380 ETLNIERPEPSLKIVELDDTYEEEFEEAENIVPYKVKLADADSQRSCAFHDCQK------ 433
+ + + KI EL EE EE E + K+ + QRS + ++
Sbjct: 1099 DDEQVHSLQFQKKIKELQARIEELEEEIEAEHTLRAKI---EKQRSDLARELEEISERLE 1155
Query: 434 -----NSFPYENGIHQHHVFDKGKRDFLNLCLRNSSTYYKDNSKAETSNTDFDNIVDP-D 487
S E + F K +RD L++ +T K S + +D
Sbjct: 1156 EASGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKQADSVAELGEQIDNLQ 1215
Query: 488 VYSSDIEKIEESTSFERNLKEKNIGLESNQKS--DDSCVSLESK-DTLLGRDLEKAPIEE 544
+EK + E + NI S KS + +C ++E + + +D ++ +
Sbjct: 1216 RVKQKLEKEKSELKMEIDDMASNIEALSKSKSNIERTCRTVEDQFSEIKAKDEQQTQLIH 1275
Query: 545 KLSQDIKESLELSNLYKRPSFEESKTTKSSLLLQEIACRSKPITKQYQGLERFFIFDT-- 602
L+ K L+ N EE ++ L+ ++ + +T+Q + L+R +T
Sbjct: 1276 DLNMQ-KARLQTQNGELSHRVEEKES-----LISQLTKSKQALTQQLEELKRQMEEETKA 1329
Query: 603 -NERLNLLPSHRLECNNSSTRITLAGQKSQRPSTANFPLSNSVKESSSCLSSSHPRSRSA 661
N + L S R +C+ L ++ + A L ++ +++S ++ + +
Sbjct: 1330 KNAMAHALQSSRHDCD-------LLREQYEEEQEAKAELQRALSKANSEVAQWRTKYETD 1382
Query: 662 AAQ-------SSSRAASEISEIEYIDITDQNE-LSLDDTTD--QHTLDNLEKELQVLRSL 711
A Q + + A + E E T ++ SL+ T Q +++L ++L+ +
Sbjct: 1383 AIQRTEELEEAKKKLAQRLQEAEENTETANSKCASLEKTKQRLQGEVEDLMRDLERSHTA 1442
Query: 712 ADTSEK 717
T +K
Sbjct: 1443 CATLDK 1448
>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
sapiens]
Length = 1843
Score = 39.7 bits (91), Expect = 0.011
Identities = 73/320 (22%), Positives = 134/320 (41%), Gaps = 47/320 (14%)
Query: 19 KLKYRNAQELRMEKVQLEFENQEMEKKLQEFRSTRNK-EKEDRESSEYYWKSGKVGKLVN 77
K K A+EL E LE EN+ ++KK+ + T K E ++E+SE ++ K+ K ++
Sbjct: 621 KEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLD 680
Query: 78 QSYMMSQNKGNVVKFSAGKVKLKLLKEQIQEPVKPTVNYKMANSSECEKPKINGKVCGQC 137
++ ++ K ++ + L + E +K + KMA Q
Sbjct: 681 SFKNLTFQLESLEKENSQLDEENLELRRNVESLK-CASMKMAQL--------------QL 725
Query: 138 ENKAALLVCLECGEDYCSGCFAKVHQKGALKLHRTTLLQAKSQILFNVLDVAHQFIKDVN 197
ENK LE ++ +KG L + + ++ + LD+ +Q ++
Sbjct: 726 ENKE-----LESEKEQL--------KKGLELLKASFKKTERLEVSYQGLDIENQRLQKTL 772
Query: 198 PDEPKEENNSTKETSKIQHKPKSVLLQRSSSEVEITTMKRAQRTKPRKSLLCEGSFDEEA 257
+ K+ E ++ + ++ LQ++ E++I++ + Q K KSL E S E+
Sbjct: 773 ENSNKKIQQLESELQDLEMENQT--LQKNLEELKISSKRLEQLEKENKSLEQETSQLEKD 830
Query: 258 SAQSFQEVLSQWRTGNHDDNKKQNLHAAVKDSLEECEVQTNLKIWR-EPLNIELKEDILS 316
Q +E NK+ A +KD+ E + N+KI E N L ++I
Sbjct: 831 KKQLEKE------------NKRLRQQAEIKDTTLE---ENNVKIGNLEKENKTLSKEIGI 875
Query: 317 YMEKLWLKKHRRTPQEQLFK 336
Y E K ++L K
Sbjct: 876 YKESCVRLKELEKENKELVK 895
Score = 37.4 bits (85), Expect = 0.055
Identities = 103/582 (17%), Positives = 229/582 (39%), Gaps = 53/582 (9%)
Query: 33 VQLEFENQEMEKKLQEFRST-----RNKEKEDRESSEYYWKSGKVGKLVNQSYMMSQNKG 87
++LE ENQ + K ++E R+T N K + E S KV L N+ Q+
Sbjct: 463 LKLEMENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQ 522
Query: 88 NVVKFSAGKVKLKLLKEQIQEPVKPTVNYKMANSSECEKPKINGKVCGQCENKAALLVCL 147
N S +K K E+ E ++ + + E E +N V L
Sbjct: 523 NCQNLSKDLMKEKAQLEKTIETLREN-SERQIKILEQENEHLNQTVSS-----------L 570
Query: 148 ECGEDYCSGCFAKVHQKGALKLHRTTLLQAKSQILFNVLDVAHQFIKDVNPDEPKEENNS 207
+ K +K LH + ++ S L + Q K++ + K E
Sbjct: 571 RQRSQISAEARVKDIEKENKILHES--IKETSSKLSKIEFEKRQIKKELEHYKEKGERAE 628
Query: 208 TKETSKIQHKPKSVLLQRSSSEVEITTMKRAQRTKPRKSLLCEGSFDEEASAQSFQEVLS 267
E + ++ LLQ+ + ++I T ++ + + S L + + + SF+ +
Sbjct: 629 ELENELHHLEKENELLQKKITNLKI-TCEKIEALEQENSELERENRKLKKTLDSFKNLTF 687
Query: 268 QWRTGNHDDNKKQNLHAAVKDSLE--ECEVQTNLKIWREPLNIELKEDILSYMEKLWLKK 325
Q + ++++ + ++ ++E +C ++ E +E +++ L +L
Sbjct: 688 QLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKAS 747
Query: 326 HRRTPQEQLFKMLPDTFPHPHETT---GDAQCSQNEND-EDSDGEETKVQHTALLLPVET 381
++T + ++ D + T + + Q E++ +D + E +Q L + +
Sbjct: 748 FKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISS 807
Query: 382 LNIERPEPSLKIVELDDTY----EEEFEEAENIVPYKVKLADADSQRSCAFHDCQKNSFP 437
+E+ E K +E + + +++ E+ + + ++ D ++N+
Sbjct: 808 KRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDT---------TLEENNVK 858
Query: 438 YENGIHQHHVFDKGKRDFLNLCLRNSSTYYKDNSKAETSNTDFDNIVD--PDVYSSDIEK 495
N ++ K + C+R ++ + + D +V D+ S ++
Sbjct: 859 IGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKT 918
Query: 496 IEESTSFERNLKE-KNIGLESNQKSDDSCVSLESKDTLLGRDLEKAPIEEKLSQDIKESL 554
+ + E+ E + IGL + D + +S+ LL E KL +K+SL
Sbjct: 919 QQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSRYKLL---------ESKLESTLKKSL 969
Query: 555 ELSNLYKRPSFEESKTTKSSLLLQEIACRSKPITKQYQGLER 596
E+ ++ + E++ +S+ Q++ K + K Y+ L++
Sbjct: 970 EIKE--EKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQ 1009
Score = 30.8 bits (68), Expect = 5.2
Identities = 23/96 (23%), Positives = 48/96 (50%), Gaps = 5/96 (5%)
Query: 18 VKLKYRNAQELRMEKVQLEFENQEMEKKLQEFRSTRNKEKEDRESSEYYWKSG--KVGKL 75
+K+ + ++L E LE E ++EK ++ + ++ E + + K+G L
Sbjct: 803 LKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNL 862
Query: 76 VNQSYMMSQNKGNVVKFSAGKVKLKLLKEQIQEPVK 111
++ +S+ G + K S V+LK L+++ +E VK
Sbjct: 863 EKENKTLSKEIG-IYKESC--VRLKELEKENKELVK 895
>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
sapiens]
Length = 1870
Score = 39.7 bits (91), Expect = 0.011
Identities = 73/320 (22%), Positives = 134/320 (41%), Gaps = 47/320 (14%)
Query: 19 KLKYRNAQELRMEKVQLEFENQEMEKKLQEFRSTRNK-EKEDRESSEYYWKSGKVGKLVN 77
K K A+EL E LE EN+ ++KK+ + T K E ++E+SE ++ K+ K ++
Sbjct: 621 KEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLD 680
Query: 78 QSYMMSQNKGNVVKFSAGKVKLKLLKEQIQEPVKPTVNYKMANSSECEKPKINGKVCGQC 137
++ ++ K ++ + L + E +K + KMA Q
Sbjct: 681 SFKNLTFQLESLEKENSQLDEENLELRRNVESLK-CASMKMAQL--------------QL 725
Query: 138 ENKAALLVCLECGEDYCSGCFAKVHQKGALKLHRTTLLQAKSQILFNVLDVAHQFIKDVN 197
ENK LE ++ +KG L + + ++ + LD+ +Q ++
Sbjct: 726 ENKE-----LESEKEQL--------KKGLELLKASFKKTERLEVSYQGLDIENQRLQKTL 772
Query: 198 PDEPKEENNSTKETSKIQHKPKSVLLQRSSSEVEITTMKRAQRTKPRKSLLCEGSFDEEA 257
+ K+ E ++ + ++ LQ++ E++I++ + Q K KSL E S E+
Sbjct: 773 ENSNKKIQQLESELQDLEMENQT--LQKNLEELKISSKRLEQLEKENKSLEQETSQLEKD 830
Query: 258 SAQSFQEVLSQWRTGNHDDNKKQNLHAAVKDSLEECEVQTNLKIWR-EPLNIELKEDILS 316
Q +E NK+ A +KD+ E + N+KI E N L ++I
Sbjct: 831 KKQLEKE------------NKRLRQQAEIKDTTLE---ENNVKIGNLEKENKTLSKEIGI 875
Query: 317 YMEKLWLKKHRRTPQEQLFK 336
Y E K ++L K
Sbjct: 876 YKESCVRLKELEKENKELVK 895
Score = 38.9 bits (89), Expect = 0.019
Identities = 143/757 (18%), Positives = 300/757 (39%), Gaps = 73/757 (9%)
Query: 33 VQLEFENQEMEKKLQEFRST-----RNKEKEDRESSEYYWKSGKVGKLVNQSYMMSQNKG 87
++LE ENQ + K ++E R+T N K + E S KV L N+ Q+
Sbjct: 463 LKLEMENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQ 522
Query: 88 NVVKFSAGKVKLKLLKEQIQEPVKPTVNYKMANSSECEKPKINGKVCGQCENKAALLVCL 147
N S +K K E+ E ++ + + E E +N V L
Sbjct: 523 NCQNLSKDLMKEKAQLEKTIETLREN-SERQIKILEQENEHLNQTVSS-----------L 570
Query: 148 ECGEDYCSGCFAKVHQKGALKLHRTTLLQAKSQILFNVLDVAHQFIKDVNPDEPKEENNS 207
+ K +K LH + ++ S L + Q K++ + K E
Sbjct: 571 RQRSQISAEARVKDIEKENKILHES--IKETSSKLSKIEFEKRQIKKELEHYKEKGERAE 628
Query: 208 TKETSKIQHKPKSVLLQRSSSEVEITTMKRAQRTKPRKSLLCEGSFDEEASAQSFQEVLS 267
E + ++ LLQ+ + ++I T ++ + + S L + + + SF+ +
Sbjct: 629 ELENELHHLEKENELLQKKITNLKI-TCEKIEALEQENSELERENRKLKKTLDSFKNLTF 687
Query: 268 QWRTGNHDDNKKQNLHAAVKDSLE--ECEVQTNLKIWREPLNIELKEDILSYMEKLWLKK 325
Q + ++++ + ++ ++E +C ++ E +E +++ L +L
Sbjct: 688 QLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKAS 747
Query: 326 HRRTPQEQLFKMLPDTFPHPHETT---GDAQCSQNEND-EDSDGEETKVQHTALLLPVET 381
++T + ++ D + T + + Q E++ +D + E +Q L + +
Sbjct: 748 FKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISS 807
Query: 382 LNIERPEPSLKIVELDDTY----EEEFEEAENIVPYKVKLADADSQRSCAFHDCQKNSFP 437
+E+ E K +E + + +++ E+ + + ++ D ++N+
Sbjct: 808 KRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDT---------TLEENNVK 858
Query: 438 YENGIHQHHVFDKGKRDFLNLCLRNSSTYYKDNSKAETSNTDFDNIVD--PDVYSSDIEK 495
N ++ K + C+R ++ + + D +V D+ S ++
Sbjct: 859 IGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKT 918
Query: 496 IEESTSFERNLKE-KNIG------LESNQKSDDSCVSLESK-DTLLGRDLEKAPIEEKLS 547
+ + E+ E + IG L Q +DD LESK ++ L + LE I+E+
Sbjct: 919 QQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDRYKLLESKLESTLKKSLE---IKEEKI 975
Query: 548 QDIKESLELSNLYKRPSFEESKTTKSSLLL-------QEIACRSKPITKQYQGLERFFIF 600
++ LE S Y + +E KT K + + + S PI+ + ER
Sbjct: 976 AALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSSPPISGEDNKWERESQE 1035
Query: 601 DTNERLNLLPS-HRLECNNSSTRITLAGQKSQ--RPSTANFPLSNSVKESSSCLSSSHPR 657
T E L + +E NN++ + K+Q + T N L + S +
Sbjct: 1036 TTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQ 1095
Query: 658 SRSAAAQSSS-RAASEISEIEYIDITDQN-ELSLDDTTDQHTLDNLEKELQVLRSLADT- 714
+ + Q++ + + + + +QN +L + ++ ++ +++ KE + L+SL D+
Sbjct: 1096 NTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSL 1155
Query: 715 ---SEKLYSLTSEEFPDFSSQSLNISQISTDFLKTSH 748
EKL L + ++ S IS+ T LK++H
Sbjct: 1156 IKDHEKLELLHERQASEYESL---ISKHGT--LKSAH 1187
Score = 30.8 bits (68), Expect = 5.2
Identities = 23/96 (23%), Positives = 48/96 (50%), Gaps = 5/96 (5%)
Query: 18 VKLKYRNAQELRMEKVQLEFENQEMEKKLQEFRSTRNKEKEDRESSEYYWKSG--KVGKL 75
+K+ + ++L E LE E ++EK ++ + ++ E + + K+G L
Sbjct: 803 LKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNL 862
Query: 76 VNQSYMMSQNKGNVVKFSAGKVKLKLLKEQIQEPVK 111
++ +S+ G + K S V+LK L+++ +E VK
Sbjct: 863 EKENKTLSKEIG-IYKESC--VRLKELEKENKELVK 895
>gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens]
Length = 1684
Score = 38.9 bits (89), Expect = 0.019
Identities = 74/331 (22%), Positives = 129/331 (38%), Gaps = 39/331 (11%)
Query: 469 DNSKAETSNTDFDNIVDPDVYSSDIEKIEESTSFERNLKEKNIGLESNQKSDDSCVSLES 528
+N + TSN + DN + + ++E+T E+ + EK LE D+ LES
Sbjct: 300 ENLRKATSNANQDNQICSIL-------LQENTFVEQVVNEKVKHLE------DTLKELES 346
Query: 529 KDTLLGRDLEKAPIEEKLSQDIKESLELSNLYKRPSFE------ESKTTKSSLLLQEIAC 582
+ ++L +D E ++K LE+ + + F E K + L +E C
Sbjct: 347 QHSIL-KD------EVTYMNNLKLKLEMDAQHIKDEFFHEREDLEFKINELLLAKEEQGC 399
Query: 583 RSKPITKQYQGLERFFIFDTNER----LNLLPSHRLECNNSSTRITLAGQKSQRPSTANF 638
+ + + GL + F + + +L H+ E S T + T F
Sbjct: 400 VIEKLKSELAGLNKQFCYTVEQHNREVQSLKEQHQKEI--SELNETFLSDSEKEKLTLMF 457
Query: 639 PLSNSVKESSSCLSSSHPRSRSAAAQSSSRAASEISEIEYIDITDQNELSLDDTTDQHTL 698
+ +KE C + + + S R EI + E + + + Q
Sbjct: 458 EIQG-LKEQ--CENLQQEKQEAILNYESLREIMEILQTELGESAGKISQEFESMKQQQAS 514
Query: 699 DNLEKELQVLRSLADTSEKLYSLTSEEFPDFSSQSLNISQISTDFLKT-SHVRGPCGVEE 757
D ELQ A T + T + + L+ ++ + T +++ GV
Sbjct: 515 D--VHELQQKLRTAFTEKDALLETVNRLQGENEKLLSQQELVPELENTIKNLQEKNGVYL 572
Query: 758 LSCSGRDTKIQSLLSLSESSTDEEEEDFLNK 788
LS S RDT ++ L S T EE++DF+NK
Sbjct: 573 LSLSQRDTMLKELEGKINSLT-EEKDDFINK 602
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 38.9 bits (89), Expect = 0.019
Identities = 76/425 (17%), Positives = 168/425 (39%), Gaps = 39/425 (9%)
Query: 19 KLKYRNA------QELRMEKVQLEFENQEMEKKLQEFR----STRNKEKEDRESSEYYWK 68
+LK +NA Q + EK +++ +E+++KL+ + + + + D E
Sbjct: 279 ELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSV 338
Query: 69 SGKVGKLVNQSYMMSQ-NKGNVVKFSAGKVKLKLLKEQIQEPVKPTVNYKMANSSECEKP 127
S K+ V ++ + ++ N+ K + K++ +E+IQE + + + EK
Sbjct: 339 SAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKM 398
Query: 128 KINGKVCGQCENKAALLVCLECGEDYCSGCFAKVHQKGALKLHRTTLLQAKSQILFNVLD 187
+ ++ + E K + E+ + +K + ++ K + + + +
Sbjct: 399 RRQEEMMWEKEEK------MRRQEEM-------MWEKEEKMRRQEEMMWEKEEKIRELEE 445
Query: 188 VAHQFIKDVNPDEPKEENNSTKETSKIQHKPKSVLLQRSSSEVEITTMKRAQRTKPRKSL 247
H+ K +E ++E +E K Q + + Q E +I + R + K
Sbjct: 446 KMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQ----EEKIREQEEKIREQEEKMW 501
Query: 248 LCEGSFDEEASA---QSFQEVLSQWRTGNHDDNKKQNLHAAVKDSLEECEVQTNL---KI 301
E E+ + QE WR + ++Q K+ + E E + K+
Sbjct: 502 RQEEKIHEQEKIREEEKRQEQEEMWR--QEEKIREQEEIWRQKEKIHEQEEKIRKQEEKM 559
Query: 302 WREPLNI-ELKEDILSYMEKLWLKKHRRTPQEQLFKMLPDTFPHPHETTGDAQCSQNEND 360
WR+ + + +E I EK+W ++ + QE+ + + E T + + E +
Sbjct: 560 WRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQE 619
Query: 361 EDSDGEETKVQHTALLLPVETLNIERPEPSLKIVELDDTYEEEF--EEAENIVPYKVKLA 418
E +E K+Q + + I E ++ E +EE E+ E + + K+
Sbjct: 620 EKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMC 679
Query: 419 DADSQ 423
+ + +
Sbjct: 680 EQEEK 684
>gi|154354990 ankyrin repeat domain 26 [Homo sapiens]
Length = 1710
Score = 38.5 bits (88), Expect = 0.025
Identities = 145/825 (17%), Positives = 313/825 (37%), Gaps = 110/825 (13%)
Query: 2 NRKDFVVLPWGKPGNSVKLKYRNAQELRMEKVQLEFENQEMEKKLQEFRSTRNKEKEDRE 61
N + + + K + V + R E + K QLE + E E++L R + N+E+E R
Sbjct: 744 NHCELLTVKIKKMEDKVNVLQRELSETKEIKSQLEHQKVEWERELCSLRFSLNQEEEKRR 803
Query: 62 SSE-YYWKSGKVGKLVNQSYMMSQNKGNVVKFSAG--KVKLKLLKEQIQEPVKPTVNYKM 118
+++ Y K + + + Y ++ S +++L+ +K + + V+ + +
Sbjct: 804 NADTLYEKIREQLRRKEEQYRKEVEVKQQLELSLQTLEMELRTVKSNLNQVVQERNDAQR 863
Query: 119 ANSSECEKPKINGKVCGQCENKAALLVCLECGEDYCSGCFAKVHQKGALKLHRTTLLQAK 178
S E + G N + +E + + + H++ H+ ++LQ +
Sbjct: 864 QLSREQNARMLQD---GILTNHLSKQKEIEMAQKKMNSENSHSHEEEKDLSHKNSMLQEE 920
Query: 179 SQILFNVLDVAHQFIKDVNPDEP----------KEENNSTKETSKIQHKPKSVLLQRSSS 228
+L +D IK+ N ++ KE+N ++T K + + + + +
Sbjct: 921 IAMLRLEIDT----IKNQNQEKEKKCFEDLKIVKEKNEDLQKTIKQNEETLTQTISQYNG 976
Query: 229 EVEITTMKRA------QRTKPRKSLLCEGSFDEEASAQSFQEVL-SQWRTGNHDDNKKQN 281
+ + T + A + K K L EA +S+ L + + + K+
Sbjct: 977 RLSVLTAENAMLNSKLENEKQSKERL-------EAEVESYHSRLAAAIHDRDQSETSKRE 1029
Query: 282 LHAAVKDSLEECEVQTNLKIWREPLNIELKEDILSYMEKLWLKKHRRTPQEQLFKMLPDT 341
L A + + +EC + K+ + N++ +ILS ++L+ + + E F D
Sbjct: 1030 LELAFQRARDECS-RLQDKMNFDVSNLKDNNEILS--QQLFKTESKLNSLEIEFHHTRDA 1086
Query: 342 -------FPHPHETTGDAQCSQNENDEDSDGEETKV-QHTALLLPV-ETLNIERPEPSLK 392
+ QC E ++ E+ KV ++ V E L+ + E L
Sbjct: 1087 LREKTLGLERVQKDLSQTQCQMKEMEQKYQNEQVKVNKYIGKQESVEERLSQLQSENMLL 1146
Query: 393 IVELDDTYEEEFEEAENIVPYK------VKLADADSQRSCAF------------HDCQKN 434
+LDD + + + + ++ + V+ A+S++ + ++
Sbjct: 1147 RQQLDDAHNKADNKEKTVINIQDQFHAIVQKLQAESEKQSLLLEERNKELISECNHLKER 1206
Query: 435 SFPYENGIHQHHVF---------DKGKRDFLNLCLRNSSTYYKDNSKAETSNT-----DF 480
+ YEN + V D K+ ++ ++ Y+ N + ET +
Sbjct: 1207 QYQYENEKAEREVVVRQLQQELADTLKKQSMSEASLEVTSRYRINLEDETQDLKKKLGQI 1266
Query: 481 DNIVD--PDVYSSDIEKIEESTSFERNLKEKNIGLESNQKSDDSCVSLESKDTLLGRDLE 538
N + D ++ + E+ ++ L++ N L+ K + E + LL +L
Sbjct: 1267 RNQLQEAQDRHTEAVRCAEKMQDHKQKLEKDNAKLKVTVKKQMDKIE-ELQKNLLNANLS 1325
Query: 539 KAPIEE-KLSQDIKESLELS---NLYKRPSFEESKTTKSSLLLQEIACRSKPITKQYQGL 594
+ E+ K ++K+SLE + + K E T +LL ++ +Y+
Sbjct: 1326 EDEKEQLKKLMELKQSLECNLDQEMKKNVELEREITGFKNLLKM-----TRKKLNEYENG 1380
Query: 595 ERFF-------IFDTNERLNLLPSHRLECNNSSTRITLAGQKSQRPSTANFPLS------ 641
E F F+ + ++N L H+++ + + + AG K T N L
Sbjct: 1381 EFSFHGDLKTSQFEMDIQINKL-KHKID--DLTAELETAGSKCLHLDTKNQILQEELLSM 1437
Query: 642 NSVKESSSCLSSSHPRSRSAAAQSSSRAASEISEIEYIDITDQNELSLDDTTDQHTLDNL 701
+V++ L + + S + E+ + Q + +++ Q + L
Sbjct: 1438 KTVQKKCEKLQKNKKKLEQEVINLRSHIERNMVELGQV---KQYKQEIEERARQEIAEKL 1494
Query: 702 EKELQVLRSLADTSEKLYSLTSEEFPDFSSQ-SLNISQISTDFLK 745
++ L++ A + E L F SQ L I + ++ K
Sbjct: 1495 KEVNLFLQAQAASQENLEQFRENNFASMKSQMELRIKDLESELSK 1539
>gi|30794488 kinesin family member 27 [Homo sapiens]
Length = 1401
Score = 37.7 bits (86), Expect = 0.042
Identities = 90/447 (20%), Positives = 173/447 (38%), Gaps = 71/447 (15%)
Query: 353 QCSQNENDEDSDGEE---TKVQHTALLLPVETLNIERPEPSLKIVELDDTYEEEFEEAEN 409
Q S N +DE+S+G+E T+ + + I++P+ +VEL DT +E
Sbjct: 641 QFSDNSDDEESEGQEKSGTRCRSRSW--------IQKPDSVCSLVELSDTQDE------- 685
Query: 410 IVPYKVKLADADSQRSCAFHDCQKNSFPYENGIHQHHVFDKGKRDFLNLCLRNSSTYYKD 469
K L + D + C + N +N + + K+ L + + K+
Sbjct: 686 --TQKSDLENEDLKIDCLQESQELNLQKLKN---SERILTEAKQKMRELTI---NIKMKE 737
Query: 470 NSKAETSNTDFDNIVDPDVYSSDIEKIEESTSFERNLKEKNIGLESNQKSDDSCVSLESK 529
+ E T D YS + K+ E + ++ + L QK LE+K
Sbjct: 738 DLIKELIKTGNDAKSVSKQYSLKVTKL------EHDAEQAKVELIETQK---QLQELENK 788
Query: 530 DTLLGRDLEKAPIEEKLSQDIKESLELSNLYKRPSFEESKTTKSSLLLQEIACRSKPITK 589
DL ++ KL ++ ++ ++ + L + ++ + +K ++A S K
Sbjct: 789 ------DLSDVAMKVKLQKEFRKKMDAAKLRVQVLQKKQQDSK------KLASLSIQNEK 836
Query: 590 QYQGLERFFIFDTNERLNLLPSHRLECNNSSTRITLAGQKSQRPSTANFPLSNSVKESSS 649
+ LE+ +++ L +L N + A K + L +E
Sbjct: 837 RANELEQSVDHMKYQKIQL--QRKLREENEKRKQLDAVIKRDQQKIKEIQLKTGQEEGLK 894
Query: 650 CLSSSHPRSRSAAAQSSSRAASEISEIEYIDITDQNELSLDDTTD-----QHTLDNLEKE 704
P++ A + R I+++ D+ + LD+ + + L+ LE +
Sbjct: 895 ------PKAEDLDACNLKRRKGSFGSIDHLQKLDEQKKWLDEEVEKVLNQRQELEELEAD 948
Query: 705 LQVLRSLADTSEKLYSLTSEEFPDFSSQSLNISQ-ISTDFLKTSHVRGPCGVEELSCSGR 763
L+ ++ E L +E ++ L SQ ++TD LK S R +ELS
Sbjct: 949 LKKREAIVSKKEALL----QEKSHLENKKLRSSQALNTDSLKIS-TRLNLLEQELS---- 999
Query: 764 DTKIQSLLSLSESSTD-EEEEDFLNKQ 789
+ +Q S +E T E+ + L K+
Sbjct: 1000 EKNVQLQTSTAEEKTKISEQVEVLQKE 1026
>gi|90819229 cutaneous T-cell lymphoma-associated antigen 1 isoform
1 [Homo sapiens]
Length = 745
Score = 37.4 bits (85), Expect = 0.055
Identities = 57/250 (22%), Positives = 103/250 (41%), Gaps = 58/250 (23%)
Query: 187 DVAHQFI---KDVNPDEPK--EENNSTKETSK----IQHKPKSVLLQRSSSEVEITTMKR 237
++ H+ + K++ ++ K E+N + SK ++ + KS+ Q + +++ T KR
Sbjct: 110 ELVHEILCLEKELKEEKSKHSEQNELMADISKRIQSLEDESKSLKSQVAEAKM---TFKR 166
Query: 238 AQRTKPRKSLLCEGSFDEEASAQSFQEVLSQWRTGNHDDNKKQNLHAAVKDSLEECEVQT 297
Q + R + + ++ E + Q Q+ L L+E EV
Sbjct: 167 FQANEERLEIEIQDAWKENSELQESQKQL-----------------------LQEAEV-- 201
Query: 298 NLKIWREPLNIELK-----EDILSYMEKLWLKK--HRRTPQEQLFKMLPDTFPHPHETTG 350
W+E ++ +K ED + E++ K H +T E+L KM + T
Sbjct: 202 ----WKEQVSELIKQKRTFEDSKVHAEQVLNDKENHIKTLTERLLKMKDGVAMLEEDVTD 257
Query: 351 DAQCSQNENDEDSDGEE---------TKVQHTALL-LPVETLNIERPEPSLKIVELDDTY 400
D N E DG K+ H A L ++TL ER + +++ E+D T
Sbjct: 258 DDNLELEMNSESEDGAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTK 317
Query: 401 EEEFEEAENI 410
EE E +N+
Sbjct: 318 EELTEHIKNL 327
>gi|55770834 centromere protein F [Homo sapiens]
Length = 3114
Score = 37.0 bits (84), Expect = 0.072
Identities = 66/323 (20%), Positives = 129/323 (39%), Gaps = 36/323 (11%)
Query: 469 DNSKAETSNTDFDNIVDPDVYSSDIEKIEESTSFERNLKEKNIGLESNQKSDDSCVSLES 528
+N K E +N +N ++ S +EK ++ S E +KE + + Q + S +
Sbjct: 56 ENEKTEGTNLKRENQRLMEICES-LEKTKQKISHELQVKESQVNFQEGQLN-----SGKK 109
Query: 529 KDTLLGRDLEKAPIEEKLSQDIKESLELSNLYKRPSFEESKTTKSSLLLQEIACRSKPIT 588
+ L ++L++ E + SQ +S ++S P K + L + SK
Sbjct: 110 QIEKLEQELKRCKSELERSQQAAQSADVS---LNPCNTPQKIFTTPLTPSQYYSGSK--- 163
Query: 589 KQYQGLERFFIFDTNERLNLLPSHR-LECNNSSTRI---TLAGQKSQRPSTANFPLSNSV 644
Y+ L+ + + ER L + L+ +S + T+ + R ++ S
Sbjct: 164 --YEDLKEKYNKEVEERKRLEAEVKALQAKKASQTLPQATMNHRDIARHQASSSVFSWQQ 221
Query: 645 KESSSCLSSSHPRSR-----SAAAQSSSRAASEISEIEYIDITDQNELSLDDTTDQHTLD 699
+++ S LSS+ R+ SA+ S + + I D N D+++ H LD
Sbjct: 222 EKTPSHLSSNSQRTPIRRDFSASYFSGEQEVTPSRSTLQIGKRDANSSFFDNSSSPHLLD 281
Query: 700 NLEKELQVLRSLADTSE-KLYSLTSE---EFPDFSSQSLNISQISTDFLKTSHVRGPCGV 755
L+ + Q LR+ + E +L E + F L + + + ++ V C
Sbjct: 282 QLKAQNQELRNKINELELRLQGHEKEMKGQVNKFQELQLQLEKAKVELIEKEKVLNKC-- 339
Query: 756 EELSCSGRDTKIQSLLSLSESST 778
RD +++ ++ST
Sbjct: 340 -------RDELVRTTAQYDQAST 355
Score = 34.3 bits (77), Expect = 0.47
Identities = 53/216 (24%), Positives = 94/216 (43%), Gaps = 25/216 (11%)
Query: 199 DEPKE---ENNSTKETSKIQHKPKSVLLQRSSSEVEITTMKRAQRTKPRKSLLCEGSFDE 255
D+ KE EN+ K++ HK + + E+ ++ + K ++LL + +
Sbjct: 2662 DQLKELTLENSELKKSLDCMHKDQVEKEGKVREEIAEYQLRLHEAEKKHQALLLDTNKQY 2721
Query: 256 EASAQSFQEVLSQWRTGNHDDNKKQNLHAAVKDSLEECEVQTNLKIWREPLNIELKE--- 312
E Q+++E L T + Q L + S +E E+ +LK + L ELK+
Sbjct: 2722 EVEIQTYREKL----TSKEECLSSQKLEIDLLKSSKE-ELNNSLKATTQILE-ELKKTKM 2775
Query: 313 DILSYMEKLWLKKHRRTPQEQLFKMLPDTFPHPHETTGDAQCSQNENDEDSDGEETKVQH 372
D L Y+ + LKK Q ++ K+L + E + + Q E + +E +
Sbjct: 2776 DNLKYVNQ--LKKENERAQGKM-KLLIKSCKQLEE---EKEILQKELSQLQAAQEKQKTG 2829
Query: 373 TALLLPVETLNIERPEPSLKIVELDDTYEEEFEEAE 408
T + V+ L E I EL +T EE+ +EA+
Sbjct: 2830 TVMDTKVDELTTE-------IKELKETLEEKTKEAD 2858
>gi|156139122 CXXC finger 6 [Homo sapiens]
Length = 2136
Score = 36.6 bits (83), Expect = 0.095
Identities = 54/207 (26%), Positives = 93/207 (44%), Gaps = 19/207 (9%)
Query: 537 LEKAPIEEKLSQDIKESLELSNLYKRPSFEESKTTKSSLLLQEIACRSKPITKQYQGLER 596
LE+ E L+Q + E S+ K EES+ +SLL +C++ T + + L+
Sbjct: 888 LEQVVAIEALTQLSEAPSENSSPSKSEKDEESEQRTASLLN---SCKAILYTVR-KDLQD 943
Query: 597 FFIFDTNERLNLLPSHRLECNNSSTRITLAGQKSQRPSTANFPLSNSVKESSSCLSSSHP 656
+ +LN PS LE +S + GQ + + +N ++++ ++S+ SH
Sbjct: 944 PNLQGEPPKLNHCPS--LEKQSSCNTVVFNGQTT---TLSNSHINSATNQAST---KSHE 995
Query: 657 RSRSAAAQSSSRAASEISEIEYIDITDQNELSLDD-TTDQHTLDNLEKELQVLRSLADTS 715
S+ + S S S+I+ Q ++LD+ + D H L E++ L D+S
Sbjct: 996 YSKVTNSLSLFIPKSNSSKIDTNKSIAQGIITLDNCSNDLHQLPPRNNEVEYCNQLLDSS 1055
Query: 716 EKLYSLTSEEFPDFSSQSLNISQISTD 742
+KL S D S Q +QI D
Sbjct: 1056 KKLDS------DDLSCQDATHTQIEED 1076
>gi|150378543 MYST histone acetyltransferase (monocytic leukemia) 3
[Homo sapiens]
Length = 2004
Score = 36.6 bits (83), Expect = 0.095
Identities = 48/238 (20%), Positives = 94/238 (39%), Gaps = 25/238 (10%)
Query: 340 DTFPHPHETTGDAQCSQNENDEDSDGEETKVQHTAL--LLPVETLN----------IERP 387
+ P P E + + Q E +E +GEE + + P ++ N +E
Sbjct: 1215 EDMPLPEERKEEEEM-QAEAEEAEEGEEEDAASSEVPAASPADSSNSPETETKEPEVEEE 1273
Query: 388 EPSLKIVELDDTYEEEFEEAENIVPYKVKLADADSQRSCAFHDCQKNSFPYENGIHQHHV 447
E ++ E EEE +E E P + + A A++ ++ HD + + +
Sbjct: 1274 EEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDD-HDADDEDDGHLESTKKKEL 1332
Query: 448 FDKGKRD-----------FLNLCLRNSSTYYKDNSKAETSNTDFDNIVDPDVYSSDIEKI 496
++ R+ FL+ ++ S KD + E + + D V S +
Sbjct: 1333 EEQPTREDVKEEPGVQESFLDANMQKSREKIKDKEETELDSEEEQPSHDTSVVSEQMAGS 1392
Query: 497 EESTSFERNLKEKNIGLESNQKSDDSCVSLESKDTLLGRDLEKAPIEEKLSQDIKESL 554
E+ + + KE+ I L+ ++ S + LE+ + E++ E QD +E+L
Sbjct: 1393 EDDHEEDSHTKEELIELKEEEEIPHSELDLETVQAVQSLTQEESSEHEGAYQDCEETL 1450
>gi|150378463 MYST histone acetyltransferase (monocytic leukemia) 3
[Homo sapiens]
Length = 2004
Score = 36.6 bits (83), Expect = 0.095
Identities = 48/238 (20%), Positives = 94/238 (39%), Gaps = 25/238 (10%)
Query: 340 DTFPHPHETTGDAQCSQNENDEDSDGEETKVQHTAL--LLPVETLN----------IERP 387
+ P P E + + Q E +E +GEE + + P ++ N +E
Sbjct: 1215 EDMPLPEERKEEEEM-QAEAEEAEEGEEEDAASSEVPAASPADSSNSPETETKEPEVEEE 1273
Query: 388 EPSLKIVELDDTYEEEFEEAENIVPYKVKLADADSQRSCAFHDCQKNSFPYENGIHQHHV 447
E ++ E EEE +E E P + + A A++ ++ HD + + +
Sbjct: 1274 EEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDD-HDADDEDDGHLESTKKKEL 1332
Query: 448 FDKGKRD-----------FLNLCLRNSSTYYKDNSKAETSNTDFDNIVDPDVYSSDIEKI 496
++ R+ FL+ ++ S KD + E + + D V S +
Sbjct: 1333 EEQPTREDVKEEPGVQESFLDANMQKSREKIKDKEETELDSEEEQPSHDTSVVSEQMAGS 1392
Query: 497 EESTSFERNLKEKNIGLESNQKSDDSCVSLESKDTLLGRDLEKAPIEEKLSQDIKESL 554
E+ + + KE+ I L+ ++ S + LE+ + E++ E QD +E+L
Sbjct: 1393 EDDHEEDSHTKEELIELKEEEEIPHSELDLETVQAVQSLTQEESSEHEGAYQDCEETL 1450
>gi|150378493 MYST histone acetyltransferase (monocytic leukemia) 3
[Homo sapiens]
Length = 2004
Score = 36.6 bits (83), Expect = 0.095
Identities = 48/238 (20%), Positives = 94/238 (39%), Gaps = 25/238 (10%)
Query: 340 DTFPHPHETTGDAQCSQNENDEDSDGEETKVQHTAL--LLPVETLN----------IERP 387
+ P P E + + Q E +E +GEE + + P ++ N +E
Sbjct: 1215 EDMPLPEERKEEEEM-QAEAEEAEEGEEEDAASSEVPAASPADSSNSPETETKEPEVEEE 1273
Query: 388 EPSLKIVELDDTYEEEFEEAENIVPYKVKLADADSQRSCAFHDCQKNSFPYENGIHQHHV 447
E ++ E EEE +E E P + + A A++ ++ HD + + +
Sbjct: 1274 EEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDD-HDADDEDDGHLESTKKKEL 1332
Query: 448 FDKGKRD-----------FLNLCLRNSSTYYKDNSKAETSNTDFDNIVDPDVYSSDIEKI 496
++ R+ FL+ ++ S KD + E + + D V S +
Sbjct: 1333 EEQPTREDVKEEPGVQESFLDANMQKSREKIKDKEETELDSEEEQPSHDTSVVSEQMAGS 1392
Query: 497 EESTSFERNLKEKNIGLESNQKSDDSCVSLESKDTLLGRDLEKAPIEEKLSQDIKESL 554
E+ + + KE+ I L+ ++ S + LE+ + E++ E QD +E+L
Sbjct: 1393 EDDHEEDSHTKEELIELKEEEEIPHSELDLETVQAVQSLTQEESSEHEGAYQDCEETL 1450
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 36.2 bits (82), Expect = 0.12
Identities = 88/407 (21%), Positives = 150/407 (36%), Gaps = 50/407 (12%)
Query: 38 ENQEMEKKLQEFRSTRNKEKEDRESSEYYWKSGKVGKLVNQSYMMSQN--KGNV------ 89
E+++ KK++E RS N E + S+ + +S K G+ NQ N GN
Sbjct: 166 EDEDNSKKIKE-RSRINSSGESGDESDEFLQSRK-GQKKNQKNKPGPNIESGNEDDDASF 223
Query: 90 -----------------VKFSAGKVKLKLLKEQIQ-EPVKPTVNYKMANSSECEKPKING 131
K K KL+ LKE+ + E K + + + + E+ +
Sbjct: 224 KIKTVAQKKAEKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKS 283
Query: 132 KVCGQC------ENKAALLVCLECGEDYCSGCFAKVHQKGALKLHRTTLLQAKSQILFNV 185
KV E KA E + K +KG + + S+
Sbjct: 284 KVTVDTGVIPASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKA 343
Query: 186 LDVAHQFIKDVNPDEPKEENNSTKETSKIQHKPKSV--LLQRSSSEVEITTMKRAQRTKP 243
+ A +K+ + +EE K +++ K K L Q + +R +R K
Sbjct: 344 MQEALAKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKERKERLKK 403
Query: 244 RKSLLCEGSFDEEASAQSFQEVLSQWRTGNHDDNKKQNLHAAVKDSL-EECEVQTNLKIW 302
LL + + A A++ ++L + Q + KDSL ++ + + K
Sbjct: 404 EGKLLTKSQREARARAEATLKLL-----------QAQGVEVPSKDSLPKKRPIYEDKKRK 452
Query: 303 REPLNIELKEDILSYMEKLWLKKHRRTPQEQLFKMLPDTFPHPHETTGDAQCSQNENDED 362
+ P +E KE + ME + + + P P E T DA E
Sbjct: 453 KIPQQLESKE-VSESMELCAAVEVMEQGVPEKEETPPPVEPEEEEDTEDAGLDDWEAMA- 510
Query: 363 SDGEETKVQHTALLLPVETLNIERPEPSLKIVELDDTYEEEFEEAEN 409
SD E KV+ + + V+ E E + E +++ EEE EE E+
Sbjct: 511 SDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEEEEEEEGES 557
>gi|149363642 coiled-coil domain containing 144A [Homo sapiens]
Length = 1427
Score = 36.2 bits (82), Expect = 0.12
Identities = 42/236 (17%), Positives = 96/236 (40%), Gaps = 31/236 (13%)
Query: 16 NSVKLKYRNAQELRMEKVQLEFENQEMEKKLQEFRSTRNKEKEDRESSEYYW-------- 67
N V + E + K+QLE + E EK+L + R +E E++ +++ +
Sbjct: 668 NMVSVLQNELSETKKTKLQLELQKIEWEKELYDLRLALKQENEEKRNADMLYNKDSEQLR 727
Query: 68 -KSGKVGKLVNQSYMMSQNKGNVVKFSAGKVKLKLLKEQIQEPVKPTVNYKMANSSECEK 126
K + GK+V + N +VK +L+ ++ + V+ + + S E +
Sbjct: 728 IKEEECGKVVETKQQLKWNLRRLVK------ELRTVRNNLDLVVQERNDAQKQLSEEQDA 781
Query: 127 PKINGKVCGQCENKAALLVCLECGEDYCSGCFAKVHQKGALKLHRTTLLQAKSQILFNVL 186
+ ++ + + LE + + HQK H +LQ + +L +
Sbjct: 782 RILQDQILTSKQKE------LEMARKKMNSEISHRHQKEKDLFHEDCMLQEEIALLRLEI 835
Query: 187 DV--------AHQFIKDVNPDEPKEENNSTKETSKIQHKPKSVLLQRSSSEVEITT 234
D ++ +D+ + KE+N++ ++ K+ + + + + S ++ T
Sbjct: 836 DTIKNQNKQKEKKYFEDI--EAVKEKNDNLQKIIKLNEETLTETILQYSGQLNNLT 889
>gi|87298937 centrosomal protein 110kDa [Homo sapiens]
Length = 2325
Score = 35.8 bits (81), Expect = 0.16
Identities = 151/769 (19%), Positives = 292/769 (37%), Gaps = 131/769 (17%)
Query: 19 KLKYRNAQE----LRMEKVQLEFENQEMEKKLQEFRSTRNKEKEDRESSEYYWKSGKVGK 74
K K +NA E + +Q E + +E+E++ QE K + S + K + K
Sbjct: 1453 KEKTKNAVEKFTDAKRSLLQTESDAEELERRAQETAVNLVKADQQLRSLQADAKDLEQHK 1512
Query: 75 LVNQSYMMSQNKGNVVKFSAGKVKLKLLKEQIQEPVKPTVNYKMANSSE----------- 123
+ + + NK K S + K ++ +E K + +MA +E
Sbjct: 1513 IKQEEILKEINKIVAAKDSDFQCLSKKKEKLTEELQKLQKDIEMAERNEDHHLQVLKESE 1572
Query: 124 -------CEKPKINGKVCGQCENKAALLVCLECGEDYCSGCFAKVHQKGALKLHRTTLLQ 176
E K+ +V Q + A L D G H+K L L + +++Q
Sbjct: 1573 VLLQAKRAELEKLKSQVTSQQQEMAVL--------DRQLG-----HKKEELHLLQGSMVQ 1619
Query: 177 AKSQILFNVLDVAHQFIKDVNPDEPKEENNSTKETSKIQHKPKSVLLQRSSSEVEITTMK 236
AK+ + Q + E E+ N +E KS+L + S + E+
Sbjct: 1620 AKADL---------QEALRLGETEVTEKCNHIREV-------KSLLEELSFQKGELNV-- 1661
Query: 237 RAQRTKPRKSLLCEGSFDEEASAQSFQEVLSQWRTGNHDDNKKQNLHAAVKDSLEECEVQ 296
+ RK+ L + E ++ Q VL Q H K L LE E+Q
Sbjct: 1662 ---QISERKTQLTLIKQEIEKEEENLQVVLRQM--SKHKTELKNILDML---QLENHELQ 1713
Query: 297 TNLKIWREPLNIELKEDILSYME-KLWLKKHRRTPQEQLFKMLPDTFPHPHETTGDAQCS 355
LK+ + EL++ ++ +E KL L+ ++ Q+Q G+ +
Sbjct: 1714 -GLKLQHDQRVSELEKTQVAVLEEKLELENLQQISQQQ---------------KGEIEWQ 1757
Query: 356 QNENDEDS-DGEETKVQHTALLLPVETLNIERPEPSLKIVELDDTYEEEFEEAENIVPYK 414
+ + D + E + AL VE L+ E+ + + E D +E++ + + ++
Sbjct: 1758 KQLLERDKREIERMTAESRALQSCVECLSKEKED----LQEKCDIWEKKLAQTKRVLA-- 1811
Query: 415 VKLADADSQRSCAFHDCQKNSFPYENGIHQ-HHVFDKGKRDFLNLCLRNSSTYYKDNSKA 473
A+ +S+ Q N E + + D+ RD L+L S+ + K
Sbjct: 1812 --AAEENSKME------QSNLEKLELNVRKLQQELDQLNRDKLSLHNDISAMQQQLQEKR 1863
Query: 474 ETSNT---------DFDNIVDPDVYSSDIEK---IEESTSFERNLKEKNIGLESNQKSDD 521
E N+ D N+ D+ + + + E T ++++ E E QK +
Sbjct: 1864 EAVNSLQEELANVQDHLNLAKQDLLHTTKHQDVLLSEQTRLQKDISEWANRFEDCQKEE- 1922
Query: 522 SCVSLESKDTLLGRDLEKAPIEEKLSQDIKESLELSNLYKRPSFEESKTTKSSLLLQEIA 581
E+K L + + IEE + +++ + L K EESK S + L+E
Sbjct: 1923 -----ETKQQQL--QVLQNEIEENKLKLVQQEMMFQRLQKERESEESKLETSKVTLKEQQ 1975
Query: 582 CR-SKPITKQYQGLERFF--IFDTNERLNLLPSHRLECNN-----SSTRITLAGQKSQRP 633
+ K +T Q L++ + ER+ L C + S T+ L+ ++ Q
Sbjct: 1976 HQLEKELTDQKSKLDQVLSKVLAAEERVRTLQEEERWCESLEKTLSQTKRQLSEREQQLV 2035
Query: 634 STANFPLSNSVKESSSCLSSSHPRSRSAAAQSSSRAASEISEIEYIDITDQNELSLDDTT 693
+ L ++++ + + + R+ +A +++ ++ +++L +
Sbjct: 2036 EKSGELL--ALQKEADSMRADFSLLRNQFLTERKKAEKQVASLKEALKIQRSQLEKNLLE 2093
Query: 694 DQHTLDNLEKELQVLRSLA-DTSEKLYSLTSE------EFPDFSSQSLN 735
+ ++KE+ + +A D E+ L E E+ + Q N
Sbjct: 2094 QKQENSCIQKEMATIELVAQDNHERARRLMKELNQMQYEYTELKKQMAN 2142
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 35.4 bits (80), Expect = 0.21
Identities = 66/361 (18%), Positives = 147/361 (40%), Gaps = 25/361 (6%)
Query: 19 KLKYRNA------QELRMEKVQLEFENQEMEKKLQEFR----STRNKEKEDRESSEYYWK 68
+LK +NA Q + EK +++ +E+++KL+ + + + + D E
Sbjct: 218 ELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSV 277
Query: 69 SGKVGKLVNQSYMMSQ-NKGNVVKFSAGKVKLKLLKEQIQEPVKPTVNYKMANSSECEKP 127
S K+ V ++ + ++ N+ K + K++ +E+IQE + + + EK
Sbjct: 278 SAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKM 337
Query: 128 KINGKVCGQCENKAALLVCLECGEDYCSGCFAKVHQKGALKLHRTT-LLQAKSQILFNVL 186
+ ++ + E K + ++ ++ + K+ R ++ K + + +
Sbjct: 338 RRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELE 397
Query: 187 DVAHQFIKDVNPDEPKEENNSTKETSKIQHKPKSVLLQRSSSEVEITTMKRAQRTKPRKS 246
+ H+ K +E ++E +E K Q + + Q E +I + R + +K
Sbjct: 398 EKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQ----EEKIREQEEKIREQEKKM 453
Query: 247 LLCEGSFDEEASA---QSFQEVLSQWRTGN--HDDNKKQNLHAAVKDSLEECEVQTNLKI 301
E E+ + QE WR H+ + + + E+ Q K+
Sbjct: 454 WRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEE-KV 512
Query: 302 WREPLNI-ELKEDILSYMEKLWLKKHRRTPQEQLFKMLPDTFPHPHETTGDAQCSQNEND 360
WR+ I E +E I EK+W ++ + QE++++ + H E + + Q + D
Sbjct: 513 WRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWR--EEEKMHEQEKIWEEEKRQEQED 570
Query: 361 E 361
+
Sbjct: 571 K 571
Score = 33.9 bits (76), Expect = 0.61
Identities = 43/229 (18%), Positives = 94/229 (41%), Gaps = 29/229 (12%)
Query: 196 VNPDEPKEENNSTKETSKIQHKPKSVLLQRSSSEVEITTMKRAQRTKPRKSLLCEGSFDE 255
+ +E KE+N +K+Q K + L++ SE+++ + ++ + K LL +
Sbjct: 214 ITDEELKEKN------AKLQEKLQ--LVESEKSEIQLNVKELKRKLERAKLLLPQQQLQA 265
Query: 256 EASAQSFQEVLSQWRTGNHDDNKKQNLHAAVKDSLEECEVQTNLKIWREPLNIELKEDIL 315
EA +H + Q++ A ++ +EE E+ L +E +E I
Sbjct: 266 EA---------------DHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQ 310
Query: 316 SYMEKLWLKKHRRTPQEQLFKMLPDTFPHPHETTGDAQCSQNENDEDSDGEETKVQHTAL 375
+ EK+ ++ + QE+ + + E + + +E +E K++
Sbjct: 311 EWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQ-- 368
Query: 376 LLPVETLNIERPEPSLKIVELDDTYEEEFEEAENIVPYKVKLADADSQR 424
E + E+ E + E+ EE+ E E + + K+ + + +R
Sbjct: 369 ----EEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKR 413
>gi|19913392 regulator of G-protein signalling 3 isoform 4 [Homo
sapiens]
Length = 168
Score = 35.4 bits (80), Expect = 0.21
Identities = 27/81 (33%), Positives = 44/81 (54%), Gaps = 7/81 (8%)
Query: 664 QSSSRAASEISEI--EYIDITDQNELSLDDTTDQHTLDNLEKELQVLRSLADTSEK-LYS 720
+S S+ AS+ +I EYI I E++LD T +HT DNL+ V R D ++K ++
Sbjct: 83 KSQSKMASKAKKIFAEYIAIQACKEVNLDSYTREHTKDNLQ---SVTRGCFDLAQKRIFG 139
Query: 721 LTSEE-FPDFSSQSLNISQIS 740
L ++ +P F L + I+
Sbjct: 140 LMEKDSYPRFLRSDLYLDLIN 160
>gi|114155127 regulator of G-protein signalling 3 isoform 6 [Homo
sapiens]
Length = 1198
Score = 35.4 bits (80), Expect = 0.21
Identities = 27/81 (33%), Positives = 44/81 (54%), Gaps = 7/81 (8%)
Query: 664 QSSSRAASEISEI--EYIDITDQNELSLDDTTDQHTLDNLEKELQVLRSLADTSEK-LYS 720
+S S+ AS+ +I EYI I E++LD T +HT DNL+ V R D ++K ++
Sbjct: 1113 KSQSKMASKAKKIFAEYIAIQACKEVNLDSYTREHTKDNLQ---SVTRGCFDLAQKRIFG 1169
Query: 721 LTSEE-FPDFSSQSLNISQIS 740
L ++ +P F L + I+
Sbjct: 1170 LMEKDSYPRFLRSDLYLDLIN 1190
>gi|62865656 regulator of G-protein signalling 3 isoform 5 [Homo
sapiens]
Length = 311
Score = 35.4 bits (80), Expect = 0.21
Identities = 27/81 (33%), Positives = 44/81 (54%), Gaps = 7/81 (8%)
Query: 664 QSSSRAASEISEI--EYIDITDQNELSLDDTTDQHTLDNLEKELQVLRSLADTSEK-LYS 720
+S S+ AS+ +I EYI I E++LD T +HT DNL+ V R D ++K ++
Sbjct: 226 KSQSKMASKAKKIFAEYIAIQACKEVNLDSYTREHTKDNLQ---SVTRGCFDLAQKRIFG 282
Query: 721 LTSEE-FPDFSSQSLNISQIS 740
L ++ +P F L + I+
Sbjct: 283 LMEKDSYPRFLRSDLYLDLIN 303
>gi|10864075 regulator of G-protein signalling 3 isoform 2 [Homo
sapiens]
Length = 519
Score = 35.4 bits (80), Expect = 0.21
Identities = 27/81 (33%), Positives = 44/81 (54%), Gaps = 7/81 (8%)
Query: 664 QSSSRAASEISEI--EYIDITDQNELSLDDTTDQHTLDNLEKELQVLRSLADTSEK-LYS 720
+S S+ AS+ +I EYI I E++LD T +HT DNL+ V R D ++K ++
Sbjct: 434 KSQSKMASKAKKIFAEYIAIQACKEVNLDSYTREHTKDNLQ---SVTRGCFDLAQKRIFG 490
Query: 721 LTSEE-FPDFSSQSLNISQIS 740
L ++ +P F L + I+
Sbjct: 491 LMEKDSYPRFLRSDLYLDLIN 511
>gi|62865651 regulator of G-protein signalling 3 isoform 1 [Homo
sapiens]
Length = 917
Score = 35.4 bits (80), Expect = 0.21
Identities = 27/81 (33%), Positives = 44/81 (54%), Gaps = 7/81 (8%)
Query: 664 QSSSRAASEISEI--EYIDITDQNELSLDDTTDQHTLDNLEKELQVLRSLADTSEK-LYS 720
+S S+ AS+ +I EYI I E++LD T +HT DNL+ V R D ++K ++
Sbjct: 832 KSQSKMASKAKKIFAEYIAIQACKEVNLDSYTREHTKDNLQ---SVTRGCFDLAQKRIFG 888
Query: 721 LTSEE-FPDFSSQSLNISQIS 740
L ++ +P F L + I+
Sbjct: 889 LMEKDSYPRFLRSDLYLDLIN 909
>gi|32967605 bromodomain adjacent to zinc finger domain, 1A isoform
b [Homo sapiens]
Length = 1524
Score = 35.4 bits (80), Expect = 0.21
Identities = 72/294 (24%), Positives = 116/294 (39%), Gaps = 45/294 (15%)
Query: 158 FAKVH---QKGALKLHRTTLLQAKSQILFNVLDVAHQFIKDVNPDEPKEENNSTKETSKI 214
F K H Q G +K+ ++L K +A Q PD+P S +
Sbjct: 227 FLKQHCEPQDGVIKIKASSLSTYK---------IAEQDFSYFFPDDPPTFIFSPANRRR- 276
Query: 215 QHKPKSVLLQRSSSEVEITTMK--RAQRTKPRKSLLCEG-----SFDEEASAQSFQEVLS 267
PK + + + + T+ R++ TK R LL + +F++ + + L
Sbjct: 277 GRPPKRIHISQEDNVANKQTLASYRSKATKERDKLLKQEEMKSLAFEKAKLKREKADALE 336
Query: 268 QWRTGNHDDNKK-QNLHAAVKDS-LEECEVQTNLKIWREPLNIELKEDILSYME--KLWL 323
+ D KK + L V++ L++ E + LK+ RE +L+E+ Y+E K W
Sbjct: 337 AKKKEKEDKEKKREELKKIVEEERLKKKEEKERLKVEREKEREKLREEKRKYVEYLKQWS 396
Query: 324 KKHRRTPQEQLFKMLPDTFP----HPHETTGDAQCSQ----------NENDEDSDGEETK 369
K + L K LP+ P P E GDA + DE DG +
Sbjct: 397 KPREDMECDDL-KELPEPTPVKTRLPPEIFGDALMVLEFLNAFGELFDLQDEFPDGVTLE 455
Query: 370 VQHTALLLPVETLNIERPEPSLKIVELDDTYEEEFEEAENIVPYKVKLADADSQ 423
V AL+ + E P L L ++ EE E + K +L DAD++
Sbjct: 456 VLEEALV----GNDSEGPLCELLFFFLTAIFQAIAEEEEEVA--KEQLTDADTK 503
>gi|32967603 bromodomain adjacent to zinc finger domain, 1A isoform
a [Homo sapiens]
Length = 1556
Score = 35.4 bits (80), Expect = 0.21
Identities = 72/294 (24%), Positives = 116/294 (39%), Gaps = 45/294 (15%)
Query: 158 FAKVH---QKGALKLHRTTLLQAKSQILFNVLDVAHQFIKDVNPDEPKEENNSTKETSKI 214
F K H Q G +K+ ++L K +A Q PD+P S +
Sbjct: 227 FLKQHCEPQDGVIKIKASSLSTYK---------IAEQDFSYFFPDDPPTFIFSPANRRR- 276
Query: 215 QHKPKSVLLQRSSSEVEITTMK--RAQRTKPRKSLLCEG-----SFDEEASAQSFQEVLS 267
PK + + + + T+ R++ TK R LL + +F++ + + L
Sbjct: 277 GRPPKRIHISQEDNVANKQTLASYRSKATKERDKLLKQEEMKSLAFEKAKLKREKADALE 336
Query: 268 QWRTGNHDDNKK-QNLHAAVKDS-LEECEVQTNLKIWREPLNIELKEDILSYME--KLWL 323
+ D KK + L V++ L++ E + LK+ RE +L+E+ Y+E K W
Sbjct: 337 AKKKEKEDKEKKREELKKIVEEERLKKKEEKERLKVEREKEREKLREEKRKYVEYLKQWS 396
Query: 324 KKHRRTPQEQLFKMLPDTFP----HPHETTGDAQCSQ----------NENDEDSDGEETK 369
K + L K LP+ P P E GDA + DE DG +
Sbjct: 397 KPREDMECDDL-KELPEPTPVKTRLPPEIFGDALMVLEFLNAFGELFDLQDEFPDGVTLE 455
Query: 370 VQHTALLLPVETLNIERPEPSLKIVELDDTYEEEFEEAENIVPYKVKLADADSQ 423
V AL+ + E P L L ++ EE E + K +L DAD++
Sbjct: 456 VLEEALV----GNDSEGPLCELLFFFLTAIFQAIAEEEEEVA--KEQLTDADTK 503
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.126 0.352
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,028,710
Number of Sequences: 37866
Number of extensions: 1372975
Number of successful extensions: 7130
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 30
Number of HSP's successfully gapped in prelim test: 158
Number of HSP's that attempted gapping in prelim test: 6625
Number of HSP's gapped (non-prelim): 619
length of query: 800
length of database: 18,247,518
effective HSP length: 110
effective length of query: 690
effective length of database: 14,082,258
effective search space: 9716758020
effective search space used: 9716758020
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.