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Search of human proteins with 85540447
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|85540447 solute carrier family 26, member 11 [Homo sapiens]
(606 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|85540447 solute carrier family 26, member 11 [Homo sapiens] 1184 0.0
gi|94721259 solute carrier family 26, member 6 isoform 4 [Homo s... 226 5e-59
gi|94721257 solute carrier family 26, member 6 isoform 3 [Homo s... 226 5e-59
gi|94721255 solute carrier family 26, member 6 isoform 2 [Homo s... 226 5e-59
gi|94721253 solute carrier family 26, member 6 isoform 1 [Homo s... 226 5e-59
gi|45827800 prestin isoform b [Homo sapiens] 186 4e-47
gi|39752683 prestin isoform a [Homo sapiens] 186 4e-47
gi|45827802 prestin isoform c [Homo sapiens] 182 6e-46
gi|100913030 solute carrier family 26 member 2 [Homo sapiens] 182 1e-45
gi|4505697 pendrin [Homo sapiens] 177 3e-44
gi|47131207 solute carrier family 26, member 1 isoform a [Homo s... 176 4e-44
gi|20336272 solute carrier family 26, member 1 isoform a [Homo s... 176 4e-44
gi|4557535 solute carrier family 26, member 3 [Homo sapiens] 173 5e-43
gi|16306483 solute carrier family 26, member 7 isoform a [Homo s... 156 6e-38
gi|20336282 solute carrier family 26, member 7 isoform b [Homo s... 156 6e-38
gi|16418413 solute carrier family 26, member 9 isoform a [Homo s... 134 3e-31
gi|217272867 solute carrier family 26, member 9 isoform b [Homo ... 134 3e-31
gi|65506789 solute carrier family 26, member 10 [Homo sapiens] 132 7e-31
gi|16418457 solute carrier family 26, member 8 isoform a [Homo s... 126 7e-29
gi|45827804 prestin isoform d [Homo sapiens] 110 3e-24
gi|20336274 solute carrier family 26, member 1 isoform b [Homo s... 74 4e-13
gi|20336285 solute carrier family 26, member 8 isoform b [Homo s... 70 6e-12
gi|217272870 solute carrier family 26, member 9 isoform c [Homo ... 63 7e-10
gi|31543063 glycerate kinase isoform 1 [Homo sapiens] 32 1.3
gi|22325388 F-box protein FBG4 isoform 1 [Homo sapiens] 32 1.3
gi|18643385 F-box protein FBG4 isoform 2 [Homo sapiens] 32 1.3
gi|4503365 dolichyl-phosphate mannosyltransferase 2 [Homo sapiens] 31 2.9
gi|149944554 somatostatin receptor 4 [Homo sapiens] 30 4.9
gi|66932949 ATPase type 13A4 [Homo sapiens] 30 6.4
gi|22027554 voltage-dependent calcium channel gamma-6 subunit is... 30 8.4
>gi|85540447 solute carrier family 26, member 11 [Homo sapiens]
Length = 606
Score = 1184 bits (3063), Expect = 0.0
Identities = 606/606 (100%), Positives = 606/606 (100%)
Query: 1 MPSSVTALGQARSSGPGMAPSACCCSPAALQRRLPILAWLPSYSLQWLKMDFVAGLSVGL 60
MPSSVTALGQARSSGPGMAPSACCCSPAALQRRLPILAWLPSYSLQWLKMDFVAGLSVGL
Sbjct: 1 MPSSVTALGQARSSGPGMAPSACCCSPAALQRRLPILAWLPSYSLQWLKMDFVAGLSVGL 60
Query: 61 TAIPQALAYAEVAGLPPQYGLYSAFMGCFVYFFLGTSRDVTLGPTAIMSLLVSFYTFHEP 120
TAIPQALAYAEVAGLPPQYGLYSAFMGCFVYFFLGTSRDVTLGPTAIMSLLVSFYTFHEP
Sbjct: 61 TAIPQALAYAEVAGLPPQYGLYSAFMGCFVYFFLGTSRDVTLGPTAIMSLLVSFYTFHEP 120
Query: 121 AYAVLLAFLSGCIQLAMGVLRLGFLLDFISYPVIKGFTSAAAVTIGFGQIKNLLGLQNIP 180
AYAVLLAFLSGCIQLAMGVLRLGFLLDFISYPVIKGFTSAAAVTIGFGQIKNLLGLQNIP
Sbjct: 121 AYAVLLAFLSGCIQLAMGVLRLGFLLDFISYPVIKGFTSAAAVTIGFGQIKNLLGLQNIP 180
Query: 181 RPFFLQVYHTFLRIAETRVGDAVLGLVCMLLLLVLKLMRDHVPPVHPEMPPGVRLSRGLV 240
RPFFLQVYHTFLRIAETRVGDAVLGLVCMLLLLVLKLMRDHVPPVHPEMPPGVRLSRGLV
Sbjct: 181 RPFFLQVYHTFLRIAETRVGDAVLGLVCMLLLLVLKLMRDHVPPVHPEMPPGVRLSRGLV 240
Query: 241 WAATTARNALVVSFAALVAYSFEVTGYQPFILTGETAEGLPPVRIPPFSVTTANGTISFT 300
WAATTARNALVVSFAALVAYSFEVTGYQPFILTGETAEGLPPVRIPPFSVTTANGTISFT
Sbjct: 241 WAATTARNALVVSFAALVAYSFEVTGYQPFILTGETAEGLPPVRIPPFSVTTANGTISFT 300
Query: 301 EMVQDMGAGLAVVPLMGLLESIAVAKAFASQNNYRIDANQELLAIGLTNMLGSLVSSYPV 360
EMVQDMGAGLAVVPLMGLLESIAVAKAFASQNNYRIDANQELLAIGLTNMLGSLVSSYPV
Sbjct: 301 EMVQDMGAGLAVVPLMGLLESIAVAKAFASQNNYRIDANQELLAIGLTNMLGSLVSSYPV 360
Query: 361 TGSFGRTAVNAQSGVCTPAGGLVTGVLVLLSLDYLTSLFYYIPKSALAAVIIMAVAPLFD 420
TGSFGRTAVNAQSGVCTPAGGLVTGVLVLLSLDYLTSLFYYIPKSALAAVIIMAVAPLFD
Sbjct: 361 TGSFGRTAVNAQSGVCTPAGGLVTGVLVLLSLDYLTSLFYYIPKSALAAVIIMAVAPLFD 420
Query: 421 TKIFRTLWRVKRLDLLPLCVTFLLCFWEVQYGILAGALVSLLMLLHSAARPETKVSEGPV 480
TKIFRTLWRVKRLDLLPLCVTFLLCFWEVQYGILAGALVSLLMLLHSAARPETKVSEGPV
Sbjct: 421 TKIFRTLWRVKRLDLLPLCVTFLLCFWEVQYGILAGALVSLLMLLHSAARPETKVSEGPV 480
Query: 481 LVLQPASGLSFPAMEALREEILSRALEVSPPRCLVLECTHVCSIDYTVVLGLGELLQDFQ 540
LVLQPASGLSFPAMEALREEILSRALEVSPPRCLVLECTHVCSIDYTVVLGLGELLQDFQ
Sbjct: 481 LVLQPASGLSFPAMEALREEILSRALEVSPPRCLVLECTHVCSIDYTVVLGLGELLQDFQ 540
Query: 541 KQGVALAFVGLQVPVLRVLLSADLKGFQYFSTLEEAEKRLRQEPGTQPYNIREDSILDQK 600
KQGVALAFVGLQVPVLRVLLSADLKGFQYFSTLEEAEKRLRQEPGTQPYNIREDSILDQK
Sbjct: 541 KQGVALAFVGLQVPVLRVLLSADLKGFQYFSTLEEAEKRLRQEPGTQPYNIREDSILDQK 600
Query: 601 VALLKA 606
VALLKA
Sbjct: 601 VALLKA 606
>gi|94721259 solute carrier family 26, member 6 isoform 4 [Homo
sapiens]
Length = 738
Score = 226 bits (576), Expect = 5e-59
Identities = 149/474 (31%), Positives = 248/474 (52%), Gaps = 53/474 (11%)
Query: 28 AALQRRLPILAWLPSYSLQ-WLKMDFVAGLSVGLTAIPQALAYAEVAGLPPQYGLYSAFM 86
A L + LP+L WLP Y ++ WL D ++GLSV + +PQ LAYA +AGLPP +GLYS+F
Sbjct: 48 ALLLQHLPVLVWLPRYPVRDWLLGDLLSGLSVAIMQLPQGLAYALLAGLPPVFGLYSSFY 107
Query: 87 GCFVYFFLGTSRDVTLGPTAIMSLLVSFYT------------FHEPA-------YAVLLA 127
F+YF GTSR +++G A+MS++V T +E A A L+
Sbjct: 108 PVFIYFLFGTSRHISVGTFAVMSVMVGSVTESLAPQALNDSMINETARDAARVQVASTLS 167
Query: 128 FLSGCIQLAMGVLRLGFLLDFISYPVIKGFTSAAAVTIGFGQIKNLLGLQNIPRPFFLQV 187
L G Q+ +G++ GF++ ++S P+++G+T+AAAV + Q+K + GL L +
Sbjct: 168 VLVGLFQVGLGLIHFGFVVTYLSEPLVRGYTTAAAVQVFVSQLKYVFGLHLSSHSGPLSL 227
Query: 188 YHTFLRIA----ETRVGDAVLGLVCMLLLLVLKLMRDHVPPVHPEMPPGVRLSRGLVWAA 243
+T L + +++VG V V ++L+V+KL+ D + P PG L
Sbjct: 228 IYTVLEVCWKLPQSKVGTVVTAAVAGVVLVVVKLLNDKLQQQLPMPIPGELL-------- 279
Query: 244 TTARNALVVSFAALVAYSFEVTGYQPFILTGETAEGLPPVRIPPFSVTTANGTISFTEMV 303
T A +S+ + + FEV + +P +PP A T F+++V
Sbjct: 280 -TLIGATGISYGMGLKHRFEV----------DVVGNIPAGLVPP----VAPNTQLFSKLV 324
Query: 304 QDMGAGLAVVPLMGLLESIAVAKAFASQNNYRIDANQELLAIGLTNMLGSLVSSYPVTGS 363
+ ++G +I++ K FA ++ YR+D+NQEL+A+GL+N++G + +PV+ S
Sbjct: 325 ----GSAFTIAVVGFAIAISLGKIFALRHGYRVDSNQELVALGLSNLIGGIFQCFPVSCS 380
Query: 364 FGRTAVNAQSGVCTPAGGLVTGVLVLLSLDYLTSLFYYIPKSALAAVIIMAV-APLFDTK 422
R+ V +G + G ++ + +LL + L LF+ +PK+ LAA+II+ + L
Sbjct: 381 MSRSLVQESTGGNSQVAGAISSLFILLIIVKLGELFHDLPKAVLAAIIIVNLKGMLRQLS 440
Query: 423 IFRTLWRVKRLDLLPLCVTF-LLCFWEVQYGILAGALVSLLMLLHSAARPETKV 475
R+LW+ R DLL VTF + G++ + SLL+++ P V
Sbjct: 441 DMRSLWKANRADLLIWLVTFTATILLNLDLGLVVAVIFSLLLVVVRTQMPHYSV 494
>gi|94721257 solute carrier family 26, member 6 isoform 3 [Homo
sapiens]
Length = 740
Score = 226 bits (576), Expect = 5e-59
Identities = 149/474 (31%), Positives = 248/474 (52%), Gaps = 53/474 (11%)
Query: 28 AALQRRLPILAWLPSYSLQ-WLKMDFVAGLSVGLTAIPQALAYAEVAGLPPQYGLYSAFM 86
A L + LP+L WLP Y ++ WL D ++GLSV + +PQ LAYA +AGLPP +GLYS+F
Sbjct: 69 ALLLQHLPVLVWLPRYPVRDWLLGDLLSGLSVAIMQLPQGLAYALLAGLPPVFGLYSSFY 128
Query: 87 GCFVYFFLGTSRDVTLGPTAIMSLLVSFYT------------FHEPA-------YAVLLA 127
F+YF GTSR +++G A+MS++V T +E A A L+
Sbjct: 129 PVFIYFLFGTSRHISVGTFAVMSVMVGSVTESLAPQALNDSMINETARDAARVQVASTLS 188
Query: 128 FLSGCIQLAMGVLRLGFLLDFISYPVIKGFTSAAAVTIGFGQIKNLLGLQNIPRPFFLQV 187
L G Q+ +G++ GF++ ++S P+++G+T+AAAV + Q+K + GL L +
Sbjct: 189 VLVGLFQVGLGLIHFGFVVTYLSEPLVRGYTTAAAVQVFVSQLKYVFGLHLSSHSGPLSL 248
Query: 188 YHTFLRIA----ETRVGDAVLGLVCMLLLLVLKLMRDHVPPVHPEMPPGVRLSRGLVWAA 243
+T L + +++VG V V ++L+V+KL+ D + P PG L
Sbjct: 249 IYTVLEVCWKLPQSKVGTVVTAAVAGVVLVVVKLLNDKLQQQLPMPIPGELL-------- 300
Query: 244 TTARNALVVSFAALVAYSFEVTGYQPFILTGETAEGLPPVRIPPFSVTTANGTISFTEMV 303
T A +S+ + + FEV + +P +PP A T F+++V
Sbjct: 301 -TLIGATGISYGMGLKHRFEV----------DVVGNIPAGLVPP----VAPNTQLFSKLV 345
Query: 304 QDMGAGLAVVPLMGLLESIAVAKAFASQNNYRIDANQELLAIGLTNMLGSLVSSYPVTGS 363
+ ++G +I++ K FA ++ YR+D+NQEL+A+GL+N++G + +PV+ S
Sbjct: 346 ----GSAFTIAVVGFAIAISLGKIFALRHGYRVDSNQELVALGLSNLIGGIFQCFPVSCS 401
Query: 364 FGRTAVNAQSGVCTPAGGLVTGVLVLLSLDYLTSLFYYIPKSALAAVIIMAV-APLFDTK 422
R+ V +G + G ++ + +LL + L LF+ +PK+ LAA+II+ + L
Sbjct: 402 MSRSLVQESTGGNSQVAGAISSLFILLIIVKLGELFHDLPKAVLAAIIIVNLKGMLRQLS 461
Query: 423 IFRTLWRVKRLDLLPLCVTF-LLCFWEVQYGILAGALVSLLMLLHSAARPETKV 475
R+LW+ R DLL VTF + G++ + SLL+++ P V
Sbjct: 462 DMRSLWKANRADLLIWLVTFTATILLNLDLGLVVAVIFSLLLVVVRTQMPHYSV 515
>gi|94721255 solute carrier family 26, member 6 isoform 2 [Homo
sapiens]
Length = 758
Score = 226 bits (576), Expect = 5e-59
Identities = 149/474 (31%), Positives = 248/474 (52%), Gaps = 53/474 (11%)
Query: 28 AALQRRLPILAWLPSYSLQ-WLKMDFVAGLSVGLTAIPQALAYAEVAGLPPQYGLYSAFM 86
A L + LP+L WLP Y ++ WL D ++GLSV + +PQ LAYA +AGLPP +GLYS+F
Sbjct: 69 ALLLQHLPVLVWLPRYPVRDWLLGDLLSGLSVAIMQLPQGLAYALLAGLPPVFGLYSSFY 128
Query: 87 GCFVYFFLGTSRDVTLGPTAIMSLLVSFYT------------FHEPA-------YAVLLA 127
F+YF GTSR +++G A+MS++V T +E A A L+
Sbjct: 129 PVFIYFLFGTSRHISVGTFAVMSVMVGSVTESLAPQALNDSMINETARDAARVQVASTLS 188
Query: 128 FLSGCIQLAMGVLRLGFLLDFISYPVIKGFTSAAAVTIGFGQIKNLLGLQNIPRPFFLQV 187
L G Q+ +G++ GF++ ++S P+++G+T+AAAV + Q+K + GL L +
Sbjct: 189 VLVGLFQVGLGLIHFGFVVTYLSEPLVRGYTTAAAVQVFVSQLKYVFGLHLSSHSGPLSL 248
Query: 188 YHTFLRIA----ETRVGDAVLGLVCMLLLLVLKLMRDHVPPVHPEMPPGVRLSRGLVWAA 243
+T L + +++VG V V ++L+V+KL+ D + P PG L
Sbjct: 249 IYTVLEVCWKLPQSKVGTVVTAAVAGVVLVVVKLLNDKLQQQLPMPIPGELL-------- 300
Query: 244 TTARNALVVSFAALVAYSFEVTGYQPFILTGETAEGLPPVRIPPFSVTTANGTISFTEMV 303
T A +S+ + + FEV + +P +PP A T F+++V
Sbjct: 301 -TLIGATGISYGMGLKHRFEV----------DVVGNIPAGLVPP----VAPNTQLFSKLV 345
Query: 304 QDMGAGLAVVPLMGLLESIAVAKAFASQNNYRIDANQELLAIGLTNMLGSLVSSYPVTGS 363
+ ++G +I++ K FA ++ YR+D+NQEL+A+GL+N++G + +PV+ S
Sbjct: 346 ----GSAFTIAVVGFAIAISLGKIFALRHGYRVDSNQELVALGLSNLIGGIFQCFPVSCS 401
Query: 364 FGRTAVNAQSGVCTPAGGLVTGVLVLLSLDYLTSLFYYIPKSALAAVIIMAV-APLFDTK 422
R+ V +G + G ++ + +LL + L LF+ +PK+ LAA+II+ + L
Sbjct: 402 MSRSLVQESTGGNSQVAGAISSLFILLIIVKLGELFHDLPKAVLAAIIIVNLKGMLRQLS 461
Query: 423 IFRTLWRVKRLDLLPLCVTF-LLCFWEVQYGILAGALVSLLMLLHSAARPETKV 475
R+LW+ R DLL VTF + G++ + SLL+++ P V
Sbjct: 462 DMRSLWKANRADLLIWLVTFTATILLNLDLGLVVAVIFSLLLVVVRTQMPHYSV 515
>gi|94721253 solute carrier family 26, member 6 isoform 1 [Homo
sapiens]
Length = 759
Score = 226 bits (576), Expect = 5e-59
Identities = 149/474 (31%), Positives = 248/474 (52%), Gaps = 53/474 (11%)
Query: 28 AALQRRLPILAWLPSYSLQ-WLKMDFVAGLSVGLTAIPQALAYAEVAGLPPQYGLYSAFM 86
A L + LP+L WLP Y ++ WL D ++GLSV + +PQ LAYA +AGLPP +GLYS+F
Sbjct: 69 ALLLQHLPVLVWLPRYPVRDWLLGDLLSGLSVAIMQLPQGLAYALLAGLPPVFGLYSSFY 128
Query: 87 GCFVYFFLGTSRDVTLGPTAIMSLLVSFYT------------FHEPA-------YAVLLA 127
F+YF GTSR +++G A+MS++V T +E A A L+
Sbjct: 129 PVFIYFLFGTSRHISVGTFAVMSVMVGSVTESLAPQALNDSMINETARDAARVQVASTLS 188
Query: 128 FLSGCIQLAMGVLRLGFLLDFISYPVIKGFTSAAAVTIGFGQIKNLLGLQNIPRPFFLQV 187
L G Q+ +G++ GF++ ++S P+++G+T+AAAV + Q+K + GL L +
Sbjct: 189 VLVGLFQVGLGLIHFGFVVTYLSEPLVRGYTTAAAVQVFVSQLKYVFGLHLSSHSGPLSL 248
Query: 188 YHTFLRIA----ETRVGDAVLGLVCMLLLLVLKLMRDHVPPVHPEMPPGVRLSRGLVWAA 243
+T L + +++VG V V ++L+V+KL+ D + P PG L
Sbjct: 249 IYTVLEVCWKLPQSKVGTVVTAAVAGVVLVVVKLLNDKLQQQLPMPIPGELL-------- 300
Query: 244 TTARNALVVSFAALVAYSFEVTGYQPFILTGETAEGLPPVRIPPFSVTTANGTISFTEMV 303
T A +S+ + + FEV + +P +PP A T F+++V
Sbjct: 301 -TLIGATGISYGMGLKHRFEV----------DVVGNIPAGLVPP----VAPNTQLFSKLV 345
Query: 304 QDMGAGLAVVPLMGLLESIAVAKAFASQNNYRIDANQELLAIGLTNMLGSLVSSYPVTGS 363
+ ++G +I++ K FA ++ YR+D+NQEL+A+GL+N++G + +PV+ S
Sbjct: 346 ----GSAFTIAVVGFAIAISLGKIFALRHGYRVDSNQELVALGLSNLIGGIFQCFPVSCS 401
Query: 364 FGRTAVNAQSGVCTPAGGLVTGVLVLLSLDYLTSLFYYIPKSALAAVIIMAV-APLFDTK 422
R+ V +G + G ++ + +LL + L LF+ +PK+ LAA+II+ + L
Sbjct: 402 MSRSLVQESTGGNSQVAGAISSLFILLIIVKLGELFHDLPKAVLAAIIIVNLKGMLRQLS 461
Query: 423 IFRTLWRVKRLDLLPLCVTF-LLCFWEVQYGILAGALVSLLMLLHSAARPETKV 475
R+LW+ R DLL VTF + G++ + SLL+++ P V
Sbjct: 462 DMRSLWKANRADLLIWLVTFTATILLNLDLGLVVAVIFSLLLVVVRTQMPHYSV 515
>gi|45827800 prestin isoform b [Homo sapiens]
Length = 685
Score = 186 bits (473), Expect = 4e-47
Identities = 140/492 (28%), Positives = 235/492 (47%), Gaps = 68/492 (13%)
Query: 22 ACCCSPAALQRR----LPILAWLPSYSL-QWLKMDFVAGLSVGLTAIPQALAYAEVAGLP 76
A C+P ++ LPI WLP+Y +++ D V+G+S G+ +PQ LA+A +A +P
Sbjct: 49 AFTCTPKKIRNIIYMFLPITKWLPAYKFKEYVLGDLVSGISTGVLQLPQGLAFAMLAAVP 108
Query: 77 PQYGLYSAFMGCFVYFFLGTSRDVTLGPTAIMSLLVSFYTFH------------------ 118
P +GLYS+F +Y FLGTSR +++GP A++SL++
Sbjct: 109 PIFGLYSSFYPVIMYCFLGTSRHISIGPFAVISLMIGGVAVRLVPDDIVIPGGVNATNGT 168
Query: 119 ------EPAYAVLLAFLSGCIQLAMGVLRLGFLLDFISYPVIKGFTSAAAVTIGFGQIKN 172
A+ + LSG IQ +GV R GF+ +++ P+++GFT+AAAV + +K
Sbjct: 169 EARDALRVKVAMSVTLLSGIIQFCLGVCRFGFVAIYLTEPLVRGFTTAAAVHVFTSMLKY 228
Query: 173 LLGLQNIP-RPFFLQVYHT---FLRIAETRVGDAVLGLVCMLLLLVLKLMRDHVPPVHPE 228
L G++ F VY T + V +GL+ LLL K + P
Sbjct: 229 LFGVKTKRYSGIFSVVYSTVAVLQNVKNLNVCSLGVGLMVFGLLLGGKEFNERFKEKLPA 288
Query: 229 MPPGVRLSRGLVWAATTARNALVVSFAALVAYSFEVTGYQPFILTGETAEGLPPVRIPPF 288
P L + A + F +Y+ +V G P L LPP
Sbjct: 289 PIP-------LEFFAVVMGTGISAGFNLKESYNVDVVGTLPLGL-------LPP------ 328
Query: 289 SVTTANGTISFTEMVQDMGAGLAVVPLMGLLESIAVAKAFASQNNYRIDANQELLAIGLT 348
AN S +V +A+V G +I++AK A+++ Y++D NQEL+A+GL
Sbjct: 329 ----ANPDTSLFHLVYVDAIAIAIV---GFSVTISMAKTLANKHGYQVDGNQELIALGLC 381
Query: 349 NMLGSLVSSYPVTGSFGRTAVNAQSGVCTPAGGLVTGVLVLLSLDYLTSLFYYIPKSALA 408
N +GSL ++ ++ S R+ V +G T G + +++LL + LF +P++ L+
Sbjct: 382 NSIGSLFQTFSISCSLSRSLVQEGTGGKTQLAGCLASLMILLVILATGFLFESLPQAVLS 441
Query: 409 AVIIMAVAPLF----DTKIFRTLWRVKRLDLLPLCVTFL-LCFWEVQYGILAGALVSLLM 463
A++I+ + +F D F WR +++L TF+ F + YG++ +++LL
Sbjct: 442 AIVIVNLKGMFMQFSDLPFF---WRTSKIELTIWLTTFVSSLFLGLDYGLITAVIIALLT 498
Query: 464 LLHSAARPETKV 475
+++ P KV
Sbjct: 499 VIYRTQSPSYKV 510
>gi|39752683 prestin isoform a [Homo sapiens]
Length = 744
Score = 186 bits (473), Expect = 4e-47
Identities = 140/492 (28%), Positives = 235/492 (47%), Gaps = 68/492 (13%)
Query: 22 ACCCSPAALQRR----LPILAWLPSYSL-QWLKMDFVAGLSVGLTAIPQALAYAEVAGLP 76
A C+P ++ LPI WLP+Y +++ D V+G+S G+ +PQ LA+A +A +P
Sbjct: 49 AFTCTPKKIRNIIYMFLPITKWLPAYKFKEYVLGDLVSGISTGVLQLPQGLAFAMLAAVP 108
Query: 77 PQYGLYSAFMGCFVYFFLGTSRDVTLGPTAIMSLLVSFYTFH------------------ 118
P +GLYS+F +Y FLGTSR +++GP A++SL++
Sbjct: 109 PIFGLYSSFYPVIMYCFLGTSRHISIGPFAVISLMIGGVAVRLVPDDIVIPGGVNATNGT 168
Query: 119 ------EPAYAVLLAFLSGCIQLAMGVLRLGFLLDFISYPVIKGFTSAAAVTIGFGQIKN 172
A+ + LSG IQ +GV R GF+ +++ P+++GFT+AAAV + +K
Sbjct: 169 EARDALRVKVAMSVTLLSGIIQFCLGVCRFGFVAIYLTEPLVRGFTTAAAVHVFTSMLKY 228
Query: 173 LLGLQNIP-RPFFLQVYHT---FLRIAETRVGDAVLGLVCMLLLLVLKLMRDHVPPVHPE 228
L G++ F VY T + V +GL+ LLL K + P
Sbjct: 229 LFGVKTKRYSGIFSVVYSTVAVLQNVKNLNVCSLGVGLMVFGLLLGGKEFNERFKEKLPA 288
Query: 229 MPPGVRLSRGLVWAATTARNALVVSFAALVAYSFEVTGYQPFILTGETAEGLPPVRIPPF 288
P L + A + F +Y+ +V G P L LPP
Sbjct: 289 PIP-------LEFFAVVMGTGISAGFNLKESYNVDVVGTLPLGL-------LPP------ 328
Query: 289 SVTTANGTISFTEMVQDMGAGLAVVPLMGLLESIAVAKAFASQNNYRIDANQELLAIGLT 348
AN S +V +A+V G +I++AK A+++ Y++D NQEL+A+GL
Sbjct: 329 ----ANPDTSLFHLVYVDAIAIAIV---GFSVTISMAKTLANKHGYQVDGNQELIALGLC 381
Query: 349 NMLGSLVSSYPVTGSFGRTAVNAQSGVCTPAGGLVTGVLVLLSLDYLTSLFYYIPKSALA 408
N +GSL ++ ++ S R+ V +G T G + +++LL + LF +P++ L+
Sbjct: 382 NSIGSLFQTFSISCSLSRSLVQEGTGGKTQLAGCLASLMILLVILATGFLFESLPQAVLS 441
Query: 409 AVIIMAVAPLF----DTKIFRTLWRVKRLDLLPLCVTFL-LCFWEVQYGILAGALVSLLM 463
A++I+ + +F D F WR +++L TF+ F + YG++ +++LL
Sbjct: 442 AIVIVNLKGMFMQFSDLPFF---WRTSKIELTIWLTTFVSSLFLGLDYGLITAVIIALLT 498
Query: 464 LLHSAARPETKV 475
+++ P KV
Sbjct: 499 VIYRTQSPSYKV 510
>gi|45827802 prestin isoform c [Homo sapiens]
Length = 516
Score = 182 bits (463), Expect = 6e-46
Identities = 138/493 (27%), Positives = 236/493 (47%), Gaps = 68/493 (13%)
Query: 22 ACCCSPAALQRR----LPILAWLPSYSL-QWLKMDFVAGLSVGLTAIPQALAYAEVAGLP 76
A C+P ++ LPI WLP+Y +++ D V+G+S G+ +PQ LA+A +A +P
Sbjct: 49 AFTCTPKKIRNIIYMFLPITKWLPAYKFKEYVLGDLVSGISTGVLQLPQGLAFAMLAAVP 108
Query: 77 PQYGLYSAFMGCFVYFFLGTSRDVTLGPTAIMSLLVSFYTFH------------------ 118
P +GLYS+F +Y FLGTSR +++GP A++SL++
Sbjct: 109 PIFGLYSSFYPVIMYCFLGTSRHISIGPFAVISLMIGGVAVRLVPDDIVIPGGVNATNGT 168
Query: 119 ------EPAYAVLLAFLSGCIQLAMGVLRLGFLLDFISYPVIKGFTSAAAVTIGFGQIKN 172
A+ + LSG IQ +GV R GF+ +++ P+++GFT+AAAV + +K
Sbjct: 169 EARDALRVKVAMSVTLLSGIIQFCLGVCRFGFVAIYLTEPLVRGFTTAAAVHVFTSMLKY 228
Query: 173 LLGLQNIP-RPFFLQVYHT---FLRIAETRVGDAVLGLVCMLLLLVLKLMRDHVPPVHPE 228
L G++ F VY T + V +GL+ LLL K + P
Sbjct: 229 LFGVKTKRYSGIFSVVYSTVAVLQNVKNLNVCSLGVGLMVFGLLLGGKEFNERFKEKLPA 288
Query: 229 MPPGVRLSRGLVWAATTARNALVVSFAALVAYSFEVTGYQPFILTGETAEGLPPVRIPPF 288
P L + A + F +Y+ +V G P L LPP
Sbjct: 289 PIP-------LEFFAVVMGTGISAGFNLKESYNVDVVGTLPLGL-------LPP------ 328
Query: 289 SVTTANGTISFTEMVQDMGAGLAVVPLMGLLESIAVAKAFASQNNYRIDANQELLAIGLT 348
AN S +V +A+V G +I++AK A+++ Y++D NQEL+A+GL
Sbjct: 329 ----ANPDTSLFHLVYVDAIAIAIV---GFSVTISMAKTLANKHGYQVDGNQELIALGLC 381
Query: 349 NMLGSLVSSYPVTGSFGRTAVNAQSGVCTPAGGLVTGVLVLLSLDYLTSLFYYIPKSALA 408
N +GSL ++ ++ S R+ V +G T G + +++LL + LF +P++ L+
Sbjct: 382 NSIGSLFQTFSISCSLSRSLVQEGTGGKTQLAGCLASLMILLVILATGFLFESLPQAVLS 441
Query: 409 AVIIMAVAPLF----DTKIFRTLWRVKRLDLLPLCVTFL-LCFWEVQYGILAGALVSLLM 463
A++I+ + +F D F WR +++L TF+ F + YG++ +++LL
Sbjct: 442 AIVIVNLKGMFMQFSDLPFF---WRTSKIELTIWLTTFVSSLFLGLDYGLITAVIIALLT 498
Query: 464 LLHSAARPETKVS 476
+++ T+++
Sbjct: 499 VIYRTQSFHTEMT 511
>gi|100913030 solute carrier family 26 member 2 [Homo sapiens]
Length = 739
Score = 182 bits (461), Expect = 1e-45
Identities = 132/505 (26%), Positives = 237/505 (46%), Gaps = 81/505 (16%)
Query: 23 CCCSPAALQRR----LPILAWLPSYSLQW-LKMDFVAGLSVGLTAIPQALAYAEVAGLPP 77
C CSPA + LP+L WLP Y L+ + D ++GL VG+ +PQ++AY+ +AG P
Sbjct: 78 CQCSPAKAKNMILGFLPVLQWLPKYDLKKNILGDVMSGLIVGILLVPQSIAYSLLAGQEP 137
Query: 78 QYGLYSAFMGCFVYFFLGTSRDVTLGPTAIMSLLVSFYTFHE------------------ 119
YGLY++F +YF LGTSR +++G ++ L++ E
Sbjct: 138 VYGLYTSFFASIIYFLLGTSRHISVGIFGVLCLMIGETVDRELQKAGYDNAHSAPSLGMV 197
Query: 120 -----------------PAYAVLLA----FLSGCIQLAMGVLRLGFLLDFISYPVIKGFT 158
YA+++ F++G Q+AMG ++GF+ ++S ++ GF
Sbjct: 198 SNGSTLLNHTSDRICDKSCYAIMVGSTVTFIAGVYQVAMGFFQVGFVSVYLSDALLSGFV 257
Query: 159 SAAAVTIGFGQIKNLLGLQNIPRP-----FFLQVYHTFLRIAETRVGDAVLGLVCMLLLL 213
+ A+ TI Q K LLGL N+PR H F I +T + D + L+C+L+LL
Sbjct: 258 TGASFTILTSQAKYLLGL-NLPRTNGVGSLITTWIHVFRNIHKTNLCDLITSLLCLLVLL 316
Query: 214 VLKLMRDHVPPVHPEMPPGVRLSRGLVWAATTARNALVVSFAALVA-YSFEVTGYQPFIL 272
K + +H ++ + + +V AAT A + F L Y+ + G+ P
Sbjct: 317 PTKELNEHFKS---KLKAPIPIELVVVVAATLASH-----FGKLHENYNSSIAGHIP--- 365
Query: 273 TGETAEGLPPVRIPPFSVTTANGTISFTEMVQDMGAGLAVVPLMGLLESIAVAKAFASQN 332
G P ++P ++ ++ + + ++G ++++++ FA ++
Sbjct: 366 -----TGFMPPKVPEWN------------LIPSVAVDAIAISIIGFAITVSLSEMFAKKH 408
Query: 333 NYRIDANQELLAIGLTNMLGSLVSSYPVTGSFGRTAVNAQSGVCTPAGGLVTGVLVLLSL 392
Y + ANQE+ AIG N++ S + + + +T V +G T G+VT +++LL L
Sbjct: 409 GYTVKANQEMYAIGFCNIIPSFFHCFTTSAALAKTLVKESTGCHTQLSGVVTALVLLLVL 468
Query: 393 DYLTSLFYYIPKSALAAVIIMAV-APLFDTKIFRTLWRVKRLDLLPLCVTFL-LCFWEVQ 450
+ LFY + KS L + I+ + L + +W + R+D + VT L +
Sbjct: 469 LVIAPLFYSLQKSVLGVITIVNLRGALRKFRDLPKMWSISRMDTVIWFVTMLSSALLSTE 528
Query: 451 YGILAGALVSLLMLLHSAARPETKV 475
G+L G S+ ++ +P++ +
Sbjct: 529 IGLLVGVCFSIFCVILRTQKPKSSL 553
>gi|4505697 pendrin [Homo sapiens]
Length = 780
Score = 177 bits (448), Expect = 3e-44
Identities = 131/484 (27%), Positives = 220/484 (45%), Gaps = 68/484 (14%)
Query: 23 CCCSP----AALQRRLPILAWLPSYSL-QWLKMDFVAGLSVGLTAIPQALAYAEVAGLPP 77
C CS L+ +PIL WLP Y + +WL D ++G+S GL A Q +AYA +A +P
Sbjct: 54 CSCSRKRAFGVLKTLVPILEWLPKYRVKEWLLSDVISGVSTGLVATLQGMAYALLAAVPV 113
Query: 78 QYGLYSAFMGCFVYFFLGTSRDVTLGPTAIMSLLVSFYTFH------------------- 118
YGLYSAF YF GTSR +++GP ++SL+V
Sbjct: 114 GYGLYSAFFPILTYFIFGTSRHISVGPFPVVSLMVGSVVLSMAPDEHFLVSSSNGTVLNT 173
Query: 119 -----------EPAYAVLLAFLSGCIQLAMGVLRLGFLLDFISYPVIKGFTSAAAVTIGF 167
A L L G IQL G L++GF++ +++ P++ GFT+AAA +
Sbjct: 174 TMIDTAARDTARVLIASALTLLVGIIQLIFGGLQIGFIVRYLADPLVGGFTTAAAFQVLV 233
Query: 168 GQIKNLLGLQNIPRPFFLQVYHT----FLRIAETRVGDAVLGLVCMLLLLVLKLMRDHVP 223
Q+K +L + L + +T F I +T + D GL+ +++ + +K + D
Sbjct: 234 SQLKIVLNVSTKNYNGVLSIIYTLVEIFQNIGDTNLADFTAGLLTIVVCMAVKELNDRFR 293
Query: 224 PVHPEMPPGVRLSRGLVWAATTARNALVVSFAALVAYSFEVTGYQPFILTGETAEGLPPV 283
P P +V A ++Y + + G P
Sbjct: 294 HKIPVPIP---------------IEVIVTIIATAISYGANLEKNYNAGIVKSIPRGFLPP 338
Query: 284 RIPPFSVTTANGTISFTEMVQDMGAGLAVVPLMGLLESIAVAKAFASQNNYRIDANQELL 343
+PP S+ F+EM+ A + ++ +++V K +A++ +Y ID NQE +
Sbjct: 339 ELPPVSL--------FSEML----AASFSIAVVAYAIAVSVGKVYATKYDYTIDGNQEFI 386
Query: 344 AIGLTNMLGSLVSSYPVTGSFGRTAVNAQSGVCTPAGGLVTGVLVLLSLDYLTSLFYYIP 403
A G++N+ S + T + RTAV +G T G+++ +V++++ L L +
Sbjct: 387 AFGISNIFSGFFSCFVATTALSRTAVQESTGGKTQVAGIISAAIVMIAILALGKLLEPLQ 446
Query: 404 KSALAAVIIMAVAPLF-DTKIFRTLWRVKRLDLLPLCVTFLL-CFWEVQYGILAGALVSL 461
KS LAAV+I + +F LWR ++D + T ++ + G+LAG + L
Sbjct: 447 KSVLAAVVIANLKGMFMQLCDIPRLWRQNKIDAVIWVFTCIVSIILGLDLGLLAGLIFGL 506
Query: 462 LMLL 465
L ++
Sbjct: 507 LTVV 510
>gi|47131207 solute carrier family 26, member 1 isoform a [Homo
sapiens]
Length = 701
Score = 176 bits (447), Expect = 4e-44
Identities = 142/494 (28%), Positives = 229/494 (46%), Gaps = 73/494 (14%)
Query: 25 CSPAALQRRLPILAWLPSYS-LQWLKMDFVAGLSVGLTAIPQALAYAEVAGLPPQYGLYS 83
C A +Q LP WL Y ++L D ++GL +G+ +PQA+AY+ +AGL P Y LY+
Sbjct: 45 CVRALVQDLLPATRWLRQYRPREYLAGDVMSGLVIGIILVPQAIAYSLLAGLQPIYSLYT 104
Query: 84 AFMGCFVYFFLGTSRDVTLGPTAIMSLLVSFYTFHE------------------------ 119
+F +YF +GTSR V++G +++ L+V E
Sbjct: 105 SFFANLIYFLMGTSRHVSVGIFSLLCLMVGQVVDRELQLAGFDPSQDGLQPGANSSTLNG 164
Query: 120 ---------PAYAVLLA----FLSGCIQLAMGVLRLGFLLDFISYPVIKGFTSAAAVTIG 166
YA+ +A ++G Q+ MGVLRLGF+ ++S P++ GF A+VTI
Sbjct: 165 SAAMLDCGRDCYAIRVATALTLMTGLYQVLMGVLRLGFVSAYLSQPLLDGFAMGASVTIL 224
Query: 167 FGQIKNLLGLQNIPRP----FFLQVYHTFLRIA-ETRVGDAVLGLVCMLLLLVLKLMRDH 221
Q+K+LLG++ IPR + + + LR A + V D V VC+ +LL K + D
Sbjct: 225 TSQLKHLLGVR-IPRHQGPGMVVLTWLSLLRGAGQANVCDVVTSTVCLAVLLAAKELSDR 283
Query: 222 VPPVHPEMPPGVRLSRGLVWAATTARNALVVSFAALVAYSFEVTGYQPFILTGETAEGLP 281
H P LV+ A LV++ ++ + G+ G
Sbjct: 284 YR--HRLRVP-------------LPTELLVIVVATLVSHFGQLHKRFGSSVAGDIPTGFM 328
Query: 282 PVRIPPFSVTTANGTISFTEMVQDMGAGLAVVPLMGLLESIAVAKAFASQNNYRIDANQE 341
P ++P ++Q + + L+ SI++A+ FA + Y + ANQE
Sbjct: 329 PPQVPE------------PRLMQRVALDAVALALVAAAFSISLAEMFARSHGYSVRANQE 376
Query: 342 LLAIGLTNMLGSLVSSYPVTGSFGRTAVNAQSGVCTPAGGLVTGVLVLLSLDYLTSLFYY 401
LLA+G N+L + + + + + ++ V +G T +V+ +VLL L L LF+
Sbjct: 377 LLAVGCCNVLPAFLHCFATSAALAKSLVKTATGCRTQLSSVVSATVVLLVLLALAPLFHD 436
Query: 402 IPKSALAAVIIMAV-APLFDTKIFRTLWRVKRLDLLPLCVTFLLCFW-EVQYGILAGALV 459
+ +S LA VI++++ L LWR+ D L T C + G+LAG ++
Sbjct: 437 LQRSVLACVIVVSLRGALRKVWDLPRLWRMSPADALVWAGTAATCMLVSTEAGLLAGVIL 496
Query: 460 SLLMLLHSAARPET 473
SLL L RP T
Sbjct: 497 SLLSLAGRTQRPRT 510
>gi|20336272 solute carrier family 26, member 1 isoform a [Homo
sapiens]
Length = 701
Score = 176 bits (447), Expect = 4e-44
Identities = 142/494 (28%), Positives = 229/494 (46%), Gaps = 73/494 (14%)
Query: 25 CSPAALQRRLPILAWLPSYS-LQWLKMDFVAGLSVGLTAIPQALAYAEVAGLPPQYGLYS 83
C A +Q LP WL Y ++L D ++GL +G+ +PQA+AY+ +AGL P Y LY+
Sbjct: 45 CVRALVQDLLPATRWLRQYRPREYLAGDVMSGLVIGIILVPQAIAYSLLAGLQPIYSLYT 104
Query: 84 AFMGCFVYFFLGTSRDVTLGPTAIMSLLVSFYTFHE------------------------ 119
+F +YF +GTSR V++G +++ L+V E
Sbjct: 105 SFFANLIYFLMGTSRHVSVGIFSLLCLMVGQVVDRELQLAGFDPSQDGLQPGANSSTLNG 164
Query: 120 ---------PAYAVLLA----FLSGCIQLAMGVLRLGFLLDFISYPVIKGFTSAAAVTIG 166
YA+ +A ++G Q+ MGVLRLGF+ ++S P++ GF A+VTI
Sbjct: 165 SAAMLDCGRDCYAIRVATALTLMTGLYQVLMGVLRLGFVSAYLSQPLLDGFAMGASVTIL 224
Query: 167 FGQIKNLLGLQNIPRP----FFLQVYHTFLRIA-ETRVGDAVLGLVCMLLLLVLKLMRDH 221
Q+K+LLG++ IPR + + + LR A + V D V VC+ +LL K + D
Sbjct: 225 TSQLKHLLGVR-IPRHQGPGMVVLTWLSLLRGAGQANVCDVVTSTVCLAVLLAAKELSDR 283
Query: 222 VPPVHPEMPPGVRLSRGLVWAATTARNALVVSFAALVAYSFEVTGYQPFILTGETAEGLP 281
H P LV+ A LV++ ++ + G+ G
Sbjct: 284 YR--HRLRVP-------------LPTELLVIVVATLVSHFGQLHKRFGSSVAGDIPTGFM 328
Query: 282 PVRIPPFSVTTANGTISFTEMVQDMGAGLAVVPLMGLLESIAVAKAFASQNNYRIDANQE 341
P ++P ++Q + + L+ SI++A+ FA + Y + ANQE
Sbjct: 329 PPQVPE------------PRLMQRVALDAVALALVAAAFSISLAEMFARSHGYSVRANQE 376
Query: 342 LLAIGLTNMLGSLVSSYPVTGSFGRTAVNAQSGVCTPAGGLVTGVLVLLSLDYLTSLFYY 401
LLA+G N+L + + + + + ++ V +G T +V+ +VLL L L LF+
Sbjct: 377 LLAVGCCNVLPAFLHCFATSAALAKSLVKTATGCRTQLSSVVSATVVLLVLLALAPLFHD 436
Query: 402 IPKSALAAVIIMAV-APLFDTKIFRTLWRVKRLDLLPLCVTFLLCFW-EVQYGILAGALV 459
+ +S LA VI++++ L LWR+ D L T C + G+LAG ++
Sbjct: 437 LQRSVLACVIVVSLRGALRKVWDLPRLWRMSPADALVWAGTAATCMLVSTEAGLLAGVIL 496
Query: 460 SLLMLLHSAARPET 473
SLL L RP T
Sbjct: 497 SLLSLAGRTQRPRT 510
>gi|4557535 solute carrier family 26, member 3 [Homo sapiens]
Length = 764
Score = 173 bits (438), Expect = 5e-43
Identities = 137/492 (27%), Positives = 225/492 (45%), Gaps = 69/492 (14%)
Query: 23 CCCSPAALQRRL----PILAWLPSYSL-QWLKMDFVAGLSVGLTAIPQALAYAEVAGLPP 77
C CSP +R + PI +WLP+Y L +WL D V+G+S G+ A+ Q LA+A + +PP
Sbjct: 43 CSCSPQKAKRIVLSLFPIASWLPAYRLKEWLLSDIVSGISTGIVAVLQGLAFALLVDIPP 102
Query: 78 QYGLYSAFMGCFVYFFLGTSRDVTLGPTAIMSLLVSFY---------------TFHEP-- 120
YGLY++F +Y F GTSR +++GP I+S++V T P
Sbjct: 103 VYGLYASFFPAIIYLFFGTSRHISVGPFPILSMMVGLAVSGAVSKAVPDRNATTLGLPNN 162
Query: 121 --------------AYAVLLAFLSGCIQLAMGVLRLGFLLDFISYPVIKGFTSAAAVTIG 166
A A + LSG IQLA G+LR+GF++ ++S +I GFT+AAAV +
Sbjct: 163 SNNSSLLDDERVRVAAAASVTVLSGIIQLAFGILRIGFVVIYLSESLISGFTTAAAVHVL 222
Query: 167 FGQIKNLLGL----QNIPRPFFLQVYHTFLRIAETRVGDAVLGLVCMLLLLVLKLMRDHV 222
Q+K + L P F +Y F +I +T + D V L+ +L++ ++K +
Sbjct: 223 VSQLKFIFQLTVPSHTDPVSIFKVLYSVFSQIEKTNIADLVTALIVLLVVSIVKEINQRF 282
Query: 223 PPVHPEMPPGVRLSRGLVWAATTARNALVVSFAALVAYSFEVTGYQPFILTGETAEGLPP 282
P P ++ AA V+Y + + G+ G P
Sbjct: 283 KDKLPVPIP---------------IEFIMTVIAAGVSYGCDFKNRFKVAVVGDMNPGFQP 327
Query: 283 VRIPPFSVTTANGTISFTEMVQDMGAGLAVVPLMGLLESIAVAKAFASQNNYRIDANQEL 342
P +F V D G+A+V + +VA ++ + +Y +D NQEL
Sbjct: 328 PITPDVE--------TFQNTVGDC-FGIAMV---AFAVAFSVASVYSLKYDYPLDGNQEL 375
Query: 343 LAIGLTNMLGSLVSSYPVTGSFGRTAVNAQSGVCTPAGGLVTGVLVLLSLDYLTSLFYYI 402
+A+GL N++ + + + + R+AV +G T GL+ ++VL+ + + L +
Sbjct: 376 IALGLGNIVCGVFRGFAGSTALSRSAVQESTGGKTQIAGLIGAIIVLIVVLAIGFLLAPL 435
Query: 403 PKSALAAVIIMAV-APLFDTKIFRTLWRVKRLDLLPLCVTFLLCF-WEVQYGILAGALVS 460
KS LAA+ + + L LWR + D L +TF+ + G+ A
Sbjct: 436 QKSVLAALALGNLKGMLMQFAEIGRLWRKDKYDCLIWIMTFIFTIVLGLGLGLAASVAFQ 495
Query: 461 LLMLLHSAARPE 472
LL ++ P+
Sbjct: 496 LLTIVFRTQFPK 507
>gi|16306483 solute carrier family 26, member 7 isoform a [Homo
sapiens]
Length = 656
Score = 156 bits (394), Expect = 6e-38
Identities = 128/477 (26%), Positives = 220/477 (46%), Gaps = 62/477 (12%)
Query: 31 QRRLPILAWLPSYSLQW-LKMDFVAGLSVGLTAIPQALAYAEVAGLPPQYGLYSAFMGCF 89
+RRLPIL W P Y+L+ L D V+G+ + + + Q LA+A ++ + P +GLY +
Sbjct: 29 RRRLPILDWAPHYNLKENLLPDTVSGIMLAVQQVTQGLAFAVLSSVHPVFGLYGSLFPAI 88
Query: 90 VYFFLGTSRDVTLGPTAIMSLL--------------------------VSFYTFHEPAYA 123
+Y G V G A+ SL+ +S + A
Sbjct: 89 IYAIFGMGHHVATGTFALTSLISANAVERIVPQNMQNLTTQSNTSVLGLSDFEMQRIHVA 148
Query: 124 VLLAFLSGCIQLAMGVLRLGFLLDFISYPVIKGFTSAAAVTIGFGQIKNLLGLQ----NI 179
++FL G IQ+AM VL+LG ++ PVI T+ AA + Q+K LLG++ +
Sbjct: 149 AAVSFLGGVIQVAMFVLQLGSATFVVTEPVISAMTTGAATHVVTSQVKYLLGMKMPYISG 208
Query: 180 PRPFFLQVYHTFLRIAETRVGDAVLGLVCMLLLLVLKLMRDHVPPVHPEMPPGVRLSRGL 239
P FF + F I R+ +L L+ +++L+++K + + + P + L
Sbjct: 209 PLGFFYIYAYVFENIKSVRLEALLLSLLSIVVLVLVKELNEQFKRKIKVVLP---VDLVL 265
Query: 240 VWAATTARNALVVSFAALVAYSFEVTGYQPFILTGETAEGLPPVRIPPFSVTTANGTISF 299
+ AA+ A + Y EV G+ P +G+P R PP ++ +A T +F
Sbjct: 266 IIAASFACYCTNMENT----YGLEVVGHIP--------QGIPSPRAPPMNILSAVITEAF 313
Query: 300 TEMVQDMGAGLAVVPLMGLLESIAVAKAFASQNNYRIDANQELLAIGLTNMLGSLVSSYP 359
V L+G + S+A+A+ A + Y ID NQE LA GL+N++ S P
Sbjct: 314 G------------VALVGYVASLALAQGSAKKFKYSIDDNQEFLAHGLSNIVSSFFFCIP 361
Query: 360 VTGSFGRTAVNAQSGVCTPAGGLVTGVLVLLSLDYLTSLFYYIPKSALAAVIIMAV-APL 418
+ GRTA +G T L++ + VL+ + + L Y++P LA++I++ + L
Sbjct: 362 SAAAMGRTAGLYSTGAKTQVACLISCIFVLIVIYAIGPLLYWLPMCVLASIIVVGLKGML 421
Query: 419 FDTKIFRTLWRVKRLD--LLPLCVTFLLCFWEVQYGILAGALVSLLMLLHSAARPET 473
+ + W V ++D + F +CF G+L G + ++ +++ R T
Sbjct: 422 IQFRDLKKYWNVDKIDWGIWVSTYVFTICF-AANVGLLFGVVCTIAIVIGRFPRAMT 477
>gi|20336282 solute carrier family 26, member 7 isoform b [Homo
sapiens]
Length = 663
Score = 156 bits (394), Expect = 6e-38
Identities = 128/477 (26%), Positives = 220/477 (46%), Gaps = 62/477 (12%)
Query: 31 QRRLPILAWLPSYSLQW-LKMDFVAGLSVGLTAIPQALAYAEVAGLPPQYGLYSAFMGCF 89
+RRLPIL W P Y+L+ L D V+G+ + + + Q LA+A ++ + P +GLY +
Sbjct: 29 RRRLPILDWAPHYNLKENLLPDTVSGIMLAVQQVTQGLAFAVLSSVHPVFGLYGSLFPAI 88
Query: 90 VYFFLGTSRDVTLGPTAIMSLL--------------------------VSFYTFHEPAYA 123
+Y G V G A+ SL+ +S + A
Sbjct: 89 IYAIFGMGHHVATGTFALTSLISANAVERIVPQNMQNLTTQSNTSVLGLSDFEMQRIHVA 148
Query: 124 VLLAFLSGCIQLAMGVLRLGFLLDFISYPVIKGFTSAAAVTIGFGQIKNLLGLQ----NI 179
++FL G IQ+AM VL+LG ++ PVI T+ AA + Q+K LLG++ +
Sbjct: 149 AAVSFLGGVIQVAMFVLQLGSATFVVTEPVISAMTTGAATHVVTSQVKYLLGMKMPYISG 208
Query: 180 PRPFFLQVYHTFLRIAETRVGDAVLGLVCMLLLLVLKLMRDHVPPVHPEMPPGVRLSRGL 239
P FF + F I R+ +L L+ +++L+++K + + + P + L
Sbjct: 209 PLGFFYIYAYVFENIKSVRLEALLLSLLSIVVLVLVKELNEQFKRKIKVVLP---VDLVL 265
Query: 240 VWAATTARNALVVSFAALVAYSFEVTGYQPFILTGETAEGLPPVRIPPFSVTTANGTISF 299
+ AA+ A + Y EV G+ P +G+P R PP ++ +A T +F
Sbjct: 266 IIAASFACYCTNMENT----YGLEVVGHIP--------QGIPSPRAPPMNILSAVITEAF 313
Query: 300 TEMVQDMGAGLAVVPLMGLLESIAVAKAFASQNNYRIDANQELLAIGLTNMLGSLVSSYP 359
V L+G + S+A+A+ A + Y ID NQE LA GL+N++ S P
Sbjct: 314 G------------VALVGYVASLALAQGSAKKFKYSIDDNQEFLAHGLSNIVSSFFFCIP 361
Query: 360 VTGSFGRTAVNAQSGVCTPAGGLVTGVLVLLSLDYLTSLFYYIPKSALAAVIIMAV-APL 418
+ GRTA +G T L++ + VL+ + + L Y++P LA++I++ + L
Sbjct: 362 SAAAMGRTAGLYSTGAKTQVACLISCIFVLIVIYAIGPLLYWLPMCVLASIIVVGLKGML 421
Query: 419 FDTKIFRTLWRVKRLD--LLPLCVTFLLCFWEVQYGILAGALVSLLMLLHSAARPET 473
+ + W V ++D + F +CF G+L G + ++ +++ R T
Sbjct: 422 IQFRDLKKYWNVDKIDWGIWVSTYVFTICF-AANVGLLFGVVCTIAIVIGRFPRAMT 477
>gi|16418413 solute carrier family 26, member 9 isoform a [Homo
sapiens]
Length = 791
Score = 134 bits (336), Expect = 3e-31
Identities = 115/470 (24%), Positives = 207/470 (44%), Gaps = 69/470 (14%)
Query: 34 LPILAWLPSYSLQ-WLKMDFVAGLSVGLTAIPQALAYAEVAGLPPQYGLYSAFMGCFVYF 92
LP+L+WLP Y ++ ++ D + GLS G +PQ +A+A +A LP GLYS+F YF
Sbjct: 56 LPVLSWLPKYKIKDYIIPDLLGGLSGGSIQVPQGMAFALLANLPAVNGLYSSFFPLLTYF 115
Query: 93 FLGTSRDVTLGPTAIMSLLV-----------SFYTFHEPA----------------YAVL 125
FLG + G A++S+LV F F+ +
Sbjct: 116 FLGGVHQMVPGTFAVISILVGNICLQLAPESKFQVFNNATNESYVDTAAMEAERLHVSAT 175
Query: 126 LAFLSGCIQLAMGVLRLGFLLDFISYPVIKGFTSAAAVTIGFGQIKNLLGLQNIPRPFFL 185
LA L+ IQ+ +G ++ GF+ ++S I+GF +AA + I +K + GL
Sbjct: 176 LACLTAIIQMGLGFMQFGFVAIYLSESFIRGFMTAAGLQILISVLKYIFGLTIPSYTGPG 235
Query: 186 QVYHTFLRIAE----TRVGDAVLGLVC-MLLLLVLKLMRDHVPPVHPEMPPGVRLSRGLV 240
+ TF+ I + T + + L+ L+LV +L ++ + +P
Sbjct: 236 SIVFTFIDICKNLPHTNIASLIFALISGAFLVLVKELNARYMHKIRFPIP---------- 285
Query: 241 WAATTARNALVVSFAALVAYSFEVTGYQPFILTGETAEGLPPVRIPPFSVTTANGTISFT 300
+VV A ++ ++ + GE G P P S
Sbjct: 286 ------TEMIVVVVATAISGGCKMPKKYHMQIVGEIQRGFPTPVSPVVS----------- 328
Query: 301 EMVQDMGAGLAVVPLMGLLESIAVAKAFASQNNYRIDANQELLAIGLTNMLGSLVSSYPV 360
+DM + ++ + ++A+ + A+++ Y +D+NQE++A+G +N GS + +
Sbjct: 329 -QWKDMIGTAFSLAIVSYVINLAMGRTLANKHGYDVDSNQEMIALGCSNFFGSFFKIHVI 387
Query: 361 TGSFGRTAVNAQSGVCTPAGGLVTGVLVLLSLDYLTSLFYYIPKSALAAVIIM----AVA 416
+ T +G + L ++V++++ L Y +PKS L A+I + ++
Sbjct: 388 CCALSVTLAVDGAGGKSQVASLCVSLVVMITMLVLGIYLYPLPKSVLGALIAVNLKNSLK 447
Query: 417 PLFDTKIFRTLWRVKRLDLLPLCVTFLLCFW-EVQYGILAGALVSLLMLL 465
L D LWR +LD V+FL F+ + YG+ G S+L+++
Sbjct: 448 QLTDPYY---LWRKSKLDCCIWVVSFLSSFFLSLPYGVAVGVAFSVLVVV 494
>gi|217272867 solute carrier family 26, member 9 isoform b [Homo
sapiens]
Length = 887
Score = 134 bits (336), Expect = 3e-31
Identities = 115/470 (24%), Positives = 207/470 (44%), Gaps = 69/470 (14%)
Query: 34 LPILAWLPSYSLQ-WLKMDFVAGLSVGLTAIPQALAYAEVAGLPPQYGLYSAFMGCFVYF 92
LP+L+WLP Y ++ ++ D + GLS G +PQ +A+A +A LP GLYS+F YF
Sbjct: 56 LPVLSWLPKYKIKDYIIPDLLGGLSGGSIQVPQGMAFALLANLPAVNGLYSSFFPLLTYF 115
Query: 93 FLGTSRDVTLGPTAIMSLLV-----------SFYTFHEPA----------------YAVL 125
FLG + G A++S+LV F F+ +
Sbjct: 116 FLGGVHQMVPGTFAVISILVGNICLQLAPESKFQVFNNATNESYVDTAAMEAERLHVSAT 175
Query: 126 LAFLSGCIQLAMGVLRLGFLLDFISYPVIKGFTSAAAVTIGFGQIKNLLGLQNIPRPFFL 185
LA L+ IQ+ +G ++ GF+ ++S I+GF +AA + I +K + GL
Sbjct: 176 LACLTAIIQMGLGFMQFGFVAIYLSESFIRGFMTAAGLQILISVLKYIFGLTIPSYTGPG 235
Query: 186 QVYHTFLRIAE----TRVGDAVLGLVC-MLLLLVLKLMRDHVPPVHPEMPPGVRLSRGLV 240
+ TF+ I + T + + L+ L+LV +L ++ + +P
Sbjct: 236 SIVFTFIDICKNLPHTNIASLIFALISGAFLVLVKELNARYMHKIRFPIP---------- 285
Query: 241 WAATTARNALVVSFAALVAYSFEVTGYQPFILTGETAEGLPPVRIPPFSVTTANGTISFT 300
+VV A ++ ++ + GE G P P S
Sbjct: 286 ------TEMIVVVVATAISGGCKMPKKYHMQIVGEIQRGFPTPVSPVVS----------- 328
Query: 301 EMVQDMGAGLAVVPLMGLLESIAVAKAFASQNNYRIDANQELLAIGLTNMLGSLVSSYPV 360
+DM + ++ + ++A+ + A+++ Y +D+NQE++A+G +N GS + +
Sbjct: 329 -QWKDMIGTAFSLAIVSYVINLAMGRTLANKHGYDVDSNQEMIALGCSNFFGSFFKIHVI 387
Query: 361 TGSFGRTAVNAQSGVCTPAGGLVTGVLVLLSLDYLTSLFYYIPKSALAAVIIM----AVA 416
+ T +G + L ++V++++ L Y +PKS L A+I + ++
Sbjct: 388 CCALSVTLAVDGAGGKSQVASLCVSLVVMITMLVLGIYLYPLPKSVLGALIAVNLKNSLK 447
Query: 417 PLFDTKIFRTLWRVKRLDLLPLCVTFLLCFW-EVQYGILAGALVSLLMLL 465
L D LWR +LD V+FL F+ + YG+ G S+L+++
Sbjct: 448 QLTDPYY---LWRKSKLDCCIWVVSFLSSFFLSLPYGVAVGVAFSVLVVV 494
>gi|65506789 solute carrier family 26, member 10 [Homo sapiens]
Length = 563
Score = 132 bits (333), Expect = 7e-31
Identities = 109/403 (27%), Positives = 183/403 (45%), Gaps = 56/403 (13%)
Query: 61 TAIPQALAYAEVAGLPPQYGLYSAFMGCFVYFFLGTSRDVTLGPTAIMSLLVSFYT---F 117
T+IP +A+A +A +PP +GLY++F +Y LGT R ++ G AI+SL+
Sbjct: 37 TSIP-GMAFALLASVPPVFGLYTSFFPVLIYSLLGTGRHLSTGTFAILSLMTGSAVERLV 95
Query: 118 HEP------------------AYAVLLAFLSGCIQLAMGVLRLGFLLDFISYPVIKGFTS 159
EP A +AF SG + L M VL+LG L F+S PV+K TS
Sbjct: 96 PEPLVGNLSGIEKEQLDAQRVGVAAAVAFGSGALMLGMFVLQLGVLSTFLSEPVVKALTS 155
Query: 160 AAAVTIGFGQIKNLLGLQNIPR-----PFFLQVYHTFLRIAETRVGDAVLGLVCMLLLLV 214
AA+ + Q+ +LLGL ++PR F + + + + + + + LL+
Sbjct: 156 GAALHVLLSQLPSLLGL-SLPRQIGCFSLFKTLASLLTALPRSSPAELTISALSLALLVP 214
Query: 215 LKLMRDHVPPVHPEMPPGVRLSRGLVWAATTARNALVVSFAALVAYSFEVTGYQPFILTG 274
+K + P PG ++V A+++ ++ V + G
Sbjct: 215 VKELNVRFRDRLPTPIPG---------------EVVLVLLASVLCFTSSVDTRYQVQIVG 259
Query: 275 ETAEGLPPVRIPPFSVTTANGTISFTEMVQDMGAGLAVVPLMGLLESIAVAKAFASQNNY 334
G P +P + E+ + + L + L+ S ++A A + +Y
Sbjct: 260 LLPGGFPQPLLP-----------NLAELPRILADSLPIA-LVSFAVSASLASIHADKYSY 307
Query: 335 RIDANQELLAIGLTNMLGSLVSSYPVTGSFGRTAVNAQSGVCTPAGGLVTGVLVLLSLDY 394
ID+NQE LA G +N++ SL S +P + + T + +G T GL + +VL L +
Sbjct: 308 TIDSNQEFLAHGASNLISSLFSCFPNSATLATTNLLVDAGGKTQLAGLFSCTVVLSVLLW 367
Query: 395 LTSLFYYIPKSALAAVIIMAVAPLF-DTKIFRTLWRVKRLDLL 436
L FYY+PK+ LA + I ++ +F + LW + R+D L
Sbjct: 368 LGPFFYYLPKAVLACINISSMRQVFCQMQELPQLWHISRVDFL 410
>gi|16418457 solute carrier family 26, member 8 isoform a [Homo
sapiens]
Length = 970
Score = 126 bits (316), Expect = 7e-29
Identities = 118/468 (25%), Positives = 201/468 (42%), Gaps = 74/468 (15%)
Query: 35 PILAWLPSYSLQ-WLKMDFVAGLSVGLTAIPQALAYAEVAG--LPPQYGLYSAFMGCFVY 91
P L W+ Y L+ WL D +AG+SVGL +PQ L + +A +PP Y+AF +Y
Sbjct: 78 PFLEWMCMYRLKDWLLGDLLAGISVGLVQVPQGLTLSLLARQLIPPLNIAYAAFCSSVIY 137
Query: 92 FFLGTSRDVTLGPTAIMSLLV-----------------SFYT--FHEPAYAV-------- 124
G+ +++G ++S L+ SF F P+Y +
Sbjct: 138 VIFGSCHQMSIGSFFLVSALLINVLKVSPFNNGQLVMGSFVKNEFSAPSYLMGYNKSLSV 197
Query: 125 --LLAFLSGCIQLAMGVLRLGFLLDFISYPVIKGFTSAAAVTIGFGQIKNLLGLQNI--- 179
FL+G IQL MGVL LGF+ ++ + + +A A+ I Q+ + G+
Sbjct: 198 VATTTFLTGIIQLIMGVLGLGFIATYLPESAMSAYLAAVALHIMLSQLTFIFGIMISFHA 257
Query: 180 -PRPFFLQVYHTFLRIAETRVGDAVLGLVCMLLLLVLKLMRDHVPPVHPEMPPGVRLSRG 238
P FF + + + + + ++ L ++ L + K +R E P + L G
Sbjct: 258 GPISFFYDIINYCVALPKANSTSILVFLTVVVALRINKCIRISFNQYPIEFPMELFLIIG 317
Query: 239 LVWAATTARNALVVS--FAALVAYSFEVTGYQPFILTGETAEGLPPVRIPPFSVTTANGT 296
A A S ++ YSF + F L LP + + FS++ +
Sbjct: 318 FTVIANKISMATETSQTLIDMIPYSFLLPVTPDFSL-------LPKIILQAFSLSLVSSF 370
Query: 297 ISFTEMVQDMGAGLAVVPLMGLLESIAVAKAFASQNNYRIDANQELLAIGLTNMLGSLVS 356
+ I + K AS +NY +++NQ+L+AIGL N++ S
Sbjct: 371 LL-----------------------IFLGKKIASLHNYSVNSNQDLIAIGLCNVVSSFFR 407
Query: 357 SYPVTGSFGRTAVNAQSGVCTPAGGLVTGVLVLLSLDYLTSLFYYIPKSALAAVIIMAVA 416
S TG+ RT + +SG LV ++LL + + FY +P + LA +I+ V
Sbjct: 408 SCVFTGAIARTIIQDKSGGRQQFASLVGAGVMLLLMVKMGHFFYTLPNAVLAGIILSNVI 467
Query: 417 PLFDT-KIFRTLWRVKRLDLLPLCVTFLLCF-WEVQYGILAGALVSLL 462
P +T +LWR + D C +++ F + G+ G ++S++
Sbjct: 468 PYLETISNLPSLWRQDQYD----CALWMMTFSSSIFLGLDIGLIISVV 511
>gi|45827804 prestin isoform d [Homo sapiens]
Length = 335
Score = 110 bits (276), Expect = 3e-24
Identities = 72/224 (32%), Positives = 113/224 (50%), Gaps = 38/224 (16%)
Query: 22 ACCCSPAALQRR----LPILAWLPSYSL-QWLKMDFVAGLSVGLTAIPQALAYAEVAGLP 76
A C+P ++ LPI WLP+Y +++ D V+G+S G+ +PQ LA+A +A +P
Sbjct: 49 AFTCTPKKIRNIIYMFLPITKWLPAYKFKEYVLGDLVSGISTGVLQLPQGLAFAMLAAVP 108
Query: 77 PQYGLYSAFMGCFVYFFLGTSRDVTLGPTAIMSLLVSFYTFH------------------ 118
P +GLYS+F +Y FLGTSR +++GP A++SL++
Sbjct: 109 PIFGLYSSFYPVIMYCFLGTSRHISIGPFAVISLMIGGVAVRLVPDDIVIPGGVNATNGT 168
Query: 119 ------EPAYAVLLAFLSGCIQLAMGVLRLGFLLDFISYPVIKGFTSAAAVTIGFGQIKN 172
A+ + LSG IQ +GV R GF+ +++ P+++GFT+AAAV + +K
Sbjct: 169 EARDALRVKVAMSVTLLSGIIQFCLGVCRFGFVAIYLTEPLVRGFTTAAAVHVFTSMLKY 228
Query: 173 LLGLQNIP-RPFFLQVYHTF--------LRIAETRVGDAVLGLV 207
L G++ F VY T L + VG V GL+
Sbjct: 229 LFGVKTKRYSGIFSVVYSTVAVLQNVKNLNVCSLGVGLMVFGLL 272
>gi|20336274 solute carrier family 26, member 1 isoform b [Homo
sapiens]
Length = 224
Score = 73.9 bits (180), Expect = 4e-13
Identities = 36/89 (40%), Positives = 57/89 (64%), Gaps = 1/89 (1%)
Query: 25 CSPAALQRRLPILAWLPSYS-LQWLKMDFVAGLSVGLTAIPQALAYAEVAGLPPQYGLYS 83
C A +Q LP WL Y ++L D ++GL +G+ +PQA+AY+ +AGL P Y LY+
Sbjct: 45 CVRALVQDLLPATRWLRQYRPREYLAGDVMSGLVIGIILVPQAIAYSLLAGLQPIYSLYT 104
Query: 84 AFMGCFVYFFLGTSRDVTLGPTAIMSLLV 112
+F +YF +GTSR V++G +++ L+V
Sbjct: 105 SFFANLIYFLMGTSRHVSVGIFSLLCLMV 133
>gi|20336285 solute carrier family 26, member 8 isoform b [Homo
sapiens]
Length = 865
Score = 70.1 bits (170), Expect = 6e-12
Identities = 44/143 (30%), Positives = 76/143 (53%), Gaps = 6/143 (4%)
Query: 322 IAVAKAFASQNNYRIDANQELLAIGLTNMLGSLVSSYPVTGSFGRTAVNAQSGVCTPAGG 381
I + K AS +NY +++NQ+L+AIGL N++ S S TG+ RT + +SG
Sbjct: 268 IFLGKKIASLHNYSVNSNQDLIAIGLCNVVSSFFRSCVFTGAIARTIIQDKSGGRQQFAS 327
Query: 382 LVTGVLVLLSLDYLTSLFYYIPKSALAAVIIMAVAPLFDT-KIFRTLWRVKRLDLLPLCV 440
LV ++LL + + FY +P + LA +I+ V P +T +LWR + D C
Sbjct: 328 LVGAGVMLLLMVKMGHFFYTLPNAVLAGIILSNVIPYLETISNLPSLWRQDQYD----CA 383
Query: 441 TFLLCF-WEVQYGILAGALVSLL 462
+++ F + G+ G ++S++
Sbjct: 384 LWMMTFSSSIFLGLDIGLIISVV 406
Score = 53.1 bits (126), Expect = 7e-07
Identities = 57/206 (27%), Positives = 87/206 (42%), Gaps = 38/206 (18%)
Query: 35 PILAWLPSYSLQ-WLKMDFVAGLSVGLTAIPQALAYAEVAG--LPPQYGLYSAFMGCFVY 91
P L W+ Y L+ WL D +AG+SVGL +PQ L + +A +PP Y+AF +Y
Sbjct: 78 PFLEWMCMYRLKDWLLGDLLAGISVGLVQVPQGLTLSLLARQLIPPLNIAYAAFCSSVIY 137
Query: 92 FFLGTSRDVTLGPTAIMSLLVSFYTFHEPAYAVLLAFLSGCIQLAMGVLRLGFLLDFISY 151
G+ +++G ++S L+ P F +G QL MG F+ + S
Sbjct: 138 VIFGSCHQMSIGSFFLVSALLINVLKVSP-------FNNG--QLVMG----SFVKNEFSA 184
Query: 152 P-VIKGFTSAAAVT------------IGFGQIKNLLGLQN---------IPRPFFLQVYH 189
P + G+ + +V IGF I N + + IP F L V
Sbjct: 185 PSYLMGYNKSLSVVATTTFLTGIIQIIGFTVIANKISMATETSQTLIDMIPYSFLLPVTP 244
Query: 190 TFLRIAETRVGDAVLGLVCMLLLLVL 215
F + + + L LV LL+ L
Sbjct: 245 DFSLLPKIILQAFSLSLVSSFLLIFL 270
>gi|217272870 solute carrier family 26, member 9 isoform c [Homo
sapiens]
Length = 459
Score = 63.2 bits (152), Expect = 7e-10
Identities = 40/150 (26%), Positives = 78/150 (52%), Gaps = 8/150 (5%)
Query: 321 SIAVAKAFASQNNYRIDANQELLAIGLTNMLGSLVSSYPVTGSFGRTAVNAQSGVCTPAG 380
++A+ + A+++ Y +D+NQE++A+G +N GS + + + T +G +
Sbjct: 16 NLAMGRTLANKHGYDVDSNQEMIALGCSNFFGSFFKIHVICCALSVTLAVDGAGGKSQVA 75
Query: 381 GLVTGVLVLLSLDYLTSLFYYIPKSALAAVIIM----AVAPLFDTKIFRTLWRVKRLDLL 436
L ++V++++ L Y +PKS L A+I + ++ L D LWR +LD
Sbjct: 76 SLCVSLVVMITMLVLGIYLYPLPKSVLGALIAVNLKNSLKQLTDPYY---LWRKSKLDCC 132
Query: 437 PLCVTFLLCFW-EVQYGILAGALVSLLMLL 465
V+FL F+ + YG+ G S+L+++
Sbjct: 133 IWVVSFLSSFFLSLPYGVAVGVAFSVLVVV 162
>gi|31543063 glycerate kinase isoform 1 [Homo sapiens]
Length = 523
Score = 32.3 bits (72), Expect = 1.3
Identities = 26/87 (29%), Positives = 37/87 (42%), Gaps = 4/87 (4%)
Query: 520 HVCSIDYTVVLGLGEL-LQDFQKQGVALAFVGLQVPVLRVLLSADLKGFQYFSTLEEAEK 578
H C V++G L L + Q+Q AL G Q VL + D+K F L
Sbjct: 299 HTCGHVLNVIIGSNVLALAEAQRQAEAL---GYQAVVLSAAMQGDVKSMAQFYGLLAHVA 355
Query: 579 RLRQEPGTQPYNIREDSILDQKVALLK 605
R R P ++ ED+ L + A L+
Sbjct: 356 RTRLTPSMAGASVEEDAQLHELAAELQ 382
>gi|22325388 F-box protein FBG4 isoform 1 [Homo sapiens]
Length = 287
Score = 32.3 bits (72), Expect = 1.3
Identities = 22/58 (37%), Positives = 30/58 (51%), Gaps = 4/58 (6%)
Query: 493 AMEALREEILSRALEVSPPRCLVLECTHVCSIDYTVVLG----LGELLQDFQKQGVAL 546
A++AL E+L + L PPR LV C VC +V G L +L +D +G AL
Sbjct: 26 ALDALPPELLVQVLSHVPPRSLVTRCRPVCRAWRDIVDGPTVWLLQLARDRSAEGRAL 83
>gi|18643385 F-box protein FBG4 isoform 2 [Homo sapiens]
Length = 278
Score = 32.3 bits (72), Expect = 1.3
Identities = 22/58 (37%), Positives = 30/58 (51%), Gaps = 4/58 (6%)
Query: 493 AMEALREEILSRALEVSPPRCLVLECTHVCSIDYTVVLG----LGELLQDFQKQGVAL 546
A++AL E+L + L PPR LV C VC +V G L +L +D +G AL
Sbjct: 17 ALDALPPELLVQVLSHVPPRSLVTRCRPVCRAWRDIVDGPTVWLLQLARDRSAEGRAL 74
>gi|4503365 dolichyl-phosphate mannosyltransferase 2 [Homo sapiens]
Length = 84
Score = 31.2 bits (69), Expect = 2.9
Identities = 24/76 (31%), Positives = 37/76 (48%), Gaps = 19/76 (25%)
Query: 95 GTSRDVTLGPTAIMSLLVSFYTFHEPAYAVLLAFLSG---------------CIQLAMGV 139
GT + V LG A+ ++ ++YT A+ +LL F+ I LA G+
Sbjct: 4 GTDQVVGLGLVAVSLIIFTYYT----AWVILLPFIDSQHVIHKYFLPRAYAVAIPLAAGL 59
Query: 140 LRLGFLLDFISYPVIK 155
L L F+ FISY ++K
Sbjct: 60 LLLLFVGLFISYVMLK 75
>gi|149944554 somatostatin receptor 4 [Homo sapiens]
Length = 388
Score = 30.4 bits (67), Expect = 4.9
Identities = 16/48 (33%), Positives = 23/48 (47%), Gaps = 1/48 (2%)
Query: 36 ILAWLPSYSLQWLKMDFVAGLSVGLTAIPQALAYAEVAGLPPQYGLYS 83
+L W+P Y +Q L + FV L + + L+YA P YG S
Sbjct: 269 VLCWMPFYVVQLLNL-FVTSLDATVNHVSLILSYANSCANPILYGFLS 315
>gi|66932949 ATPase type 13A4 [Homo sapiens]
Length = 1196
Score = 30.0 bits (66), Expect = 6.4
Identities = 24/96 (25%), Positives = 45/96 (46%), Gaps = 9/96 (9%)
Query: 156 GFTSAAAVTIGFGQIK-NLLGLQNIPRPFFLQVYHTFLRIAETRVGDAVLGLVCMLLLLV 214
G A + GF K +L+ P+P Q+Y +R VG A +G++ L + V
Sbjct: 362 GTVRAVVLQTGFNTAKGDLVRSILYPKPVNFQLYRDAIRFLLCLVGTATIGMIYTLCVYV 421
Query: 215 L------KLMRDHVPPVHPEMPPGV--RLSRGLVWA 242
L +++R + + +PP + L+ G+++A
Sbjct: 422 LSGEPPEEVVRKALDVITIAVPPALPAALTTGIIYA 457
>gi|22027554 voltage-dependent calcium channel gamma-6 subunit
isoform a [Homo sapiens]
Length = 260
Score = 29.6 bits (65), Expect = 8.4
Identities = 19/49 (38%), Positives = 25/49 (51%), Gaps = 4/49 (8%)
Query: 198 RVGDAVLGLVCMLLLLVLKLMRDHV----PPVHPEMPPGVRLSRGLVWA 242
RVG GL +LLL+ L++ R V V PE PP RL+ W+
Sbjct: 172 RVGAVCFGLSGLLLLVSLEVFRHSVRALLQRVSPEPPPAPRLTYEYSWS 220
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.325 0.140 0.416
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,692,341
Number of Sequences: 37866
Number of extensions: 899149
Number of successful extensions: 3169
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 25
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 3065
Number of HSP's gapped (non-prelim): 42
length of query: 606
length of database: 18,247,518
effective HSP length: 108
effective length of query: 498
effective length of database: 14,157,990
effective search space: 7050679020
effective search space used: 7050679020
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.