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Search of human proteins with 82880658
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|82880658 heat shock 70kDa protein 14 isoform 1 [Homo
sapiens]
(509 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|82880658 heat shock 70kDa protein 14 isoform 1 [Homo sapiens] 991 0.0
gi|13676857 heat shock 70kDa protein 2 [Homo sapiens] 321 1e-87
gi|34419635 heat shock 70kDa protein 6 (HSP70B') [Homo sapiens] 319 4e-87
gi|167466173 heat shock 70kDa protein 1B [Homo sapiens] 316 3e-86
gi|194248072 heat shock 70kDa protein 1A [Homo sapiens] 316 3e-86
gi|124256496 heat shock 70kDa protein 1-like [Homo sapiens] 314 1e-85
gi|5729877 heat shock 70kDa protein 8 isoform 1 [Homo sapiens] 310 2e-84
gi|16507237 heat shock 70kDa protein 5 [Homo sapiens] 307 2e-83
gi|24234686 heat shock 70kDa protein 8 isoform 2 [Homo sapiens] 296 2e-80
gi|24234688 heat shock 70kDa protein 9 precursor [Homo sapiens] 243 4e-64
gi|42544159 heat shock 105kD [Homo sapiens] 192 5e-49
gi|38327039 heat shock 70kDa protein 4 [Homo sapiens] 191 1e-48
gi|31541941 heat shock 70kDa protein 4-like [Homo sapiens] 189 7e-48
gi|48928056 heat shock protein 70kDa family member 13 precursor ... 170 3e-42
gi|195976805 hypoxia up-regulated 1 precursor [Homo sapiens] 154 2e-37
gi|5453832 hypoxia up-regulated 1 precursor [Homo sapiens] 154 2e-37
gi|48527957 galactokinase 2 isoform 2 [Homo sapiens] 30 4.0
gi|4503897 galactokinase 2 isoform 1 [Homo sapiens] 30 4.0
gi|226958575 RAS protein activator like 2 isoform 2 [Homo sapiens] 30 5.2
gi|4506889 mitogen-activated protein kinase kinase 4 [Homo sapiens] 29 8.9
>gi|82880658 heat shock 70kDa protein 14 isoform 1 [Homo sapiens]
Length = 509
Score = 991 bits (2563), Expect = 0.0
Identities = 509/509 (100%), Positives = 509/509 (100%)
Query: 1 MAAIGVHLGCTSACVAVYKDGRAGVVANDAGDRVTPAVVAYSENEEIVGLAAKQSRIRNI 60
MAAIGVHLGCTSACVAVYKDGRAGVVANDAGDRVTPAVVAYSENEEIVGLAAKQSRIRNI
Sbjct: 1 MAAIGVHLGCTSACVAVYKDGRAGVVANDAGDRVTPAVVAYSENEEIVGLAAKQSRIRNI 60
Query: 61 SNTVMKVKQILGRSSSDPQAQKYIAESKCLVIEKNGKLRYEIDTGEETKFVNPEDVARLI 120
SNTVMKVKQILGRSSSDPQAQKYIAESKCLVIEKNGKLRYEIDTGEETKFVNPEDVARLI
Sbjct: 61 SNTVMKVKQILGRSSSDPQAQKYIAESKCLVIEKNGKLRYEIDTGEETKFVNPEDVARLI 120
Query: 121 FSKMKETAHSVLGSDANDVVITVPFDFGEKQKNALGEAARAAGFNVLRLIHEPSAALLAY 180
FSKMKETAHSVLGSDANDVVITVPFDFGEKQKNALGEAARAAGFNVLRLIHEPSAALLAY
Sbjct: 121 FSKMKETAHSVLGSDANDVVITVPFDFGEKQKNALGEAARAAGFNVLRLIHEPSAALLAY 180
Query: 181 GIGQDSPTGKSNILVFKLGGTSLSLSVMEVNSGIYRVLSTNTDDNIGGAHFTETLAQYLA 240
GIGQDSPTGKSNILVFKLGGTSLSLSVMEVNSGIYRVLSTNTDDNIGGAHFTETLAQYLA
Sbjct: 181 GIGQDSPTGKSNILVFKLGGTSLSLSVMEVNSGIYRVLSTNTDDNIGGAHFTETLAQYLA 240
Query: 241 SEFQRSFKHDVRGNARAMMKLTNSAEVAKHSLSTLGSANCFLDSLYEGQDFDCNVSRARF 300
SEFQRSFKHDVRGNARAMMKLTNSAEVAKHSLSTLGSANCFLDSLYEGQDFDCNVSRARF
Sbjct: 241 SEFQRSFKHDVRGNARAMMKLTNSAEVAKHSLSTLGSANCFLDSLYEGQDFDCNVSRARF 300
Query: 301 ELLCSPLFNKCIEAIRGLLDQNGFTADDINKVVLCGGSSRIPKLQQLIKDLFPAVELLNS 360
ELLCSPLFNKCIEAIRGLLDQNGFTADDINKVVLCGGSSRIPKLQQLIKDLFPAVELLNS
Sbjct: 301 ELLCSPLFNKCIEAIRGLLDQNGFTADDINKVVLCGGSSRIPKLQQLIKDLFPAVELLNS 360
Query: 361 IPPDEVIPIGAAIEAGILIGKENLLVEDSLMIECSARDILVKGVDESGASRFTVLFPSGT 420
IPPDEVIPIGAAIEAGILIGKENLLVEDSLMIECSARDILVKGVDESGASRFTVLFPSGT
Sbjct: 361 IPPDEVIPIGAAIEAGILIGKENLLVEDSLMIECSARDILVKGVDESGASRFTVLFPSGT 420
Query: 421 PLPARRQHTLQAPGSISSVCLELYESDGKNSAKEETKFAQVVLQDLDKKENGLRDILAVL 480
PLPARRQHTLQAPGSISSVCLELYESDGKNSAKEETKFAQVVLQDLDKKENGLRDILAVL
Sbjct: 421 PLPARRQHTLQAPGSISSVCLELYESDGKNSAKEETKFAQVVLQDLDKKENGLRDILAVL 480
Query: 481 TMKRDGSLHVTCTDQETGKCEAISIEIAS 509
TMKRDGSLHVTCTDQETGKCEAISIEIAS
Sbjct: 481 TMKRDGSLHVTCTDQETGKCEAISIEIAS 509
>gi|13676857 heat shock 70kDa protein 2 [Homo sapiens]
Length = 639
Score = 321 bits (822), Expect = 1e-87
Identities = 180/505 (35%), Positives = 289/505 (57%), Gaps = 7/505 (1%)
Query: 3 AIGVHLGCTSACVAVYKDGRAGVVANDAGDRVTPAVVAYSENEEIVGLAAKQSRIRNISN 62
AIG+ LG T +CV V++ G+ ++AND G+R TP+ VA+++ E ++G AAK N +N
Sbjct: 7 AIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTN 66
Query: 63 TVMKVKQILGRSSSDPQAQKYIAESKCLVIEKNGKLRYEIDTGEETKFVNPEDVARLIFS 122
T+ K+++GR D Q + V+ + GK + +++ ETK PE+++ ++ +
Sbjct: 67 TIFDAKRLIGRKFEDATVQSDMKHWPFRVVSEGGKPKVQVEYKGETKTFFPEEISSMVLT 126
Query: 123 KMKETAHSVLGSDANDVVITVPFDFGEKQKNALGEAARAAGFNVLRLIHEPSAALLAYGI 182
KMKE A + LG + VITVP F + Q+ A +A G NVLR+I+EP+AA +AYG+
Sbjct: 127 KMKEIAEAYLGGKVHSAVITVPAYFNDSQRQATKDAGTITGLNVLRIINEPTAAAIAYGL 186
Query: 183 GQDSPTG-KSNILVFKLGGTSLSLSVMEVNSGIYRVLSTNTDDNIGGAHFTETLAQYLAS 241
+ G + N+L+F LGG + +S++ + GI+ V ST D ++GG F + +LA
Sbjct: 187 DKKGCAGGEKNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVSHLAE 246
Query: 242 EFQRSFKHDVRGNARAMMKLTNSAEVAKHSLSTLGSANCFLDSLYEGQDFDCNVSRARFE 301
EF+R K D+ N RA+ +L + E AK +LS+ A+ +DSLYEG DF +++RARFE
Sbjct: 247 EFKRKHKKDIGPNKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGVDFYTSITRARFE 306
Query: 302 LLCSPLFNKCIEAIRGLLDQNGFTADDINKVVLCGGSSRIPKLQQLIKDLFPAVELLNSI 361
L + LF +E + L I ++VL GGS+RIPK+Q+L++D F EL SI
Sbjct: 307 ELNADLFRGTLEPVEKALRDAKLDKGQIQEIVLVGGSTRIPKIQKLLQDFFNGKELNKSI 366
Query: 362 PPDEVIPIGAAIEAGILIGKENLLVEDSLMIECSARDILVKGVDESGASRFTVLFPSGTP 421
PDE + GAA++A ILIG ++ V+D L+++ + L G++ +G T L T
Sbjct: 367 NPDEAVAYGAAVQAAILIGDKSENVQDLLLLDVTP---LSLGIETAGGV-MTPLIKRNTT 422
Query: 422 LPARRQHTLQA-PGSISSVCLELYESDGKNSAKEETKFAQVVLQDLDKKENGLRDILAVL 480
+P ++ T + SSV +++YE + + K+ + L + G+ I
Sbjct: 423 IPTKQTQTFTTYSDNQSSVLVQVYEGE-RAMTKDNNLLGKFDLTGIPPAPRGVPQIEVTF 481
Query: 481 TMKRDGSLHVTCTDQETGKCEAISI 505
+ +G L+VT D+ TGK I+I
Sbjct: 482 DIDANGILNVTAADKSTGKENKITI 506
>gi|34419635 heat shock 70kDa protein 6 (HSP70B') [Homo sapiens]
Length = 643
Score = 319 bits (817), Expect = 4e-87
Identities = 180/504 (35%), Positives = 283/504 (56%), Gaps = 7/504 (1%)
Query: 3 AIGVHLGCTSACVAVYKDGRAGVVANDAGDRVTPAVVAYSENEEIVGLAAKQSRIRNISN 62
A+G+ LG T +CV V++ GR ++AND G+R TP+ VA+++ E +VG AAK N N
Sbjct: 8 AVGIDLGTTYSCVGVFQQGRVEILANDQGNRTTPSYVAFTDTERLVGDAAKSQAALNPHN 67
Query: 63 TVMKVKQILGRSSSDPQAQKYIAESKCLVIEKNGKLRYEIDTGEETKFVNPEDVARLIFS 122
TV K+++GR +D Q + V+ + GK + + E K PE+++ ++ S
Sbjct: 68 TVFDAKRLIGRKFADTTVQSDMKHWPFRVVSEGGKPKVRVCYRGEDKTFYPEEISSMVLS 127
Query: 123 KMKETAHSVLGSDANDVVITVPFDFGEKQKNALGEAARAAGFNVLRLIHEPSAALLAYGI 182
KMKETA + LG VITVP F + Q+ A +A AG NVLR+I+EP+AA +AYG+
Sbjct: 128 KMKETAEAYLGQPVKHAVITVPAYFNDSQRQATKDAGAIAGLNVLRIINEPTAAAIAYGL 187
Query: 183 GQDSPTGKSNILVFKLGGTSLSLSVMEVNSGIYRVLSTNTDDNIGGAHFTETLAQYLASE 242
+ G+ N+L+F LGG + +SV+ +++G++ V +T D ++GG F L + E
Sbjct: 188 DRRG-AGERNVLIFDLGGGTFDVSVLSIDAGVFEVKATAGDTHLGGEDFDNRLVNHFMEE 246
Query: 243 FQRSFKHDVRGNARAMMKLTNSAEVAKHSLSTLGSANCFLDSLYEGQDFDCNVSRARFEL 302
F+R D+ GN RA+ +L + E AK +LS+ A +DSL+EG DF +++RARFE
Sbjct: 247 FRRKHGKDLSGNKRALRRLRTACERAKRTLSSSTQATLEIDSLFEGVDFYTSITRARFEE 306
Query: 303 LCSPLFNKCIEAIRGLLDQNGFTADDINKVVLCGGSSRIPKLQQLIKDLFPAVELLNSIP 362
LCS LF +E + L I+ VVL GGS+RIPK+Q+L++D F EL SI
Sbjct: 307 LCSDLFRSTLEPVEKALRDAKLDKAQIHDVVLVGGSTRIPKVQKLLQDFFNGKELNKSIN 366
Query: 363 PDEVIPIGAAIEAGILIGKENLLVEDSLMIECSARDILVKGVDESGASRFTVLFPSGTPL 422
PDE + GAA++A +L+G + V+D L+++ + L G++ +G T L +
Sbjct: 367 PDEAVAYGAAVQAAVLMGDKCEKVQDLLLLDVAP---LSLGLETAGGV-MTTLIQRNATI 422
Query: 423 PARRQHTLQA-PGSISSVCLELYESDGKNSAKEETKFAQVVLQDLDKKENGLRDILAVLT 481
P ++ T + V +++YE + + K+ + L + G+ I
Sbjct: 423 PTKQTQTFTTYSDNQPGVFIQVYEGE-RAMTKDNNLLGRFELSGIPPAPRGVPQIEVTFD 481
Query: 482 MKRDGSLHVTCTDQETGKCEAISI 505
+ +G L VT TD+ TGK I+I
Sbjct: 482 IDANGILSVTATDRSTGKANKITI 505
>gi|167466173 heat shock 70kDa protein 1B [Homo sapiens]
Length = 641
Score = 316 bits (810), Expect = 3e-86
Identities = 178/505 (35%), Positives = 286/505 (56%), Gaps = 7/505 (1%)
Query: 2 AAIGVHLGCTSACVAVYKDGRAGVVANDAGDRVTPAVVAYSENEEIVGLAAKQSRIRNIS 61
AAIG+ LG T +CV V++ G+ ++AND G+R TP+ VA+++ E ++G AAK N
Sbjct: 5 AAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVALNPQ 64
Query: 62 NTVMKVKQILGRSSSDPQAQKYIAESKCLVIEKNGKLRYEIDTGEETKFVNPEDVARLIF 121
NTV K+++GR DP Q + VI K + ++ ETK PE+++ ++
Sbjct: 65 NTVFDAKRLIGRKFGDPVVQSDMKHWPFQVINDGDKPKVQVSYKGETKAFYPEEISSMVL 124
Query: 122 SKMKETAHSVLGSDANDVVITVPFDFGEKQKNALGEAARAAGFNVLRLIHEPSAALLAYG 181
+KMKE A + LG + VITVP F + Q+ A +A AG NVLR+I+EP+AA +AYG
Sbjct: 125 TKMKEIAEAYLGYPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYG 184
Query: 182 IGQDSPTGKSNILVFKLGGTSLSLSVMEVNSGIYRVLSTNTDDNIGGAHFTETLAQYLAS 241
+ + G+ N+L+F LGG + +S++ ++ GI+ V +T D ++GG F L +
Sbjct: 185 LDRTGK-GERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVNHFVE 243
Query: 242 EFQRSFKHDVRGNARAMMKLTNSAEVAKHSLSTLGSANCFLDSLYEGQDFDCNVSRARFE 301
EF+R K D+ N RA+ +L + E AK +LS+ A+ +DSL+EG DF +++RARFE
Sbjct: 244 EFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEIDSLFEGIDFYTSITRARFE 303
Query: 302 LLCSPLFNKCIEAIRGLLDQNGFTADDINKVVLCGGSSRIPKLQQLIKDLFPAVELLNSI 361
LCS LF +E + L I+ +VL GGS+RIPK+Q+L++D F +L SI
Sbjct: 304 ELCSDLFRSTLEPVEKALRDAKLDKAQIHDLVLVGGSTRIPKVQKLLQDFFNGRDLNKSI 363
Query: 362 PPDEVIPIGAAIEAGILIGKENLLVEDSLMIECSARDILVKGVDESGASRFTVLFPSGTP 421
PDE + GAA++A IL+G ++ V+D L+++ + L G++ +G T L +
Sbjct: 364 NPDEAVAYGAAVQAAILMGDKSENVQDLLLLDVAP---LSLGLETAGGV-MTALIKRNST 419
Query: 422 LPARRQHTLQA-PGSISSVCLELYESDGKNSAKEETKFAQVVLQDLDKKENGLRDILAVL 480
+P ++ + V +++YE + + K+ + L + G+ I
Sbjct: 420 IPTKQTQIFTTYSDNQPGVLIQVYEGE-RAMTKDNNLLGRFELSGIPPAPRGVPQIEVTF 478
Query: 481 TMKRDGSLHVTCTDQETGKCEAISI 505
+ +G L+VT TD+ TGK I+I
Sbjct: 479 DIDANGILNVTATDKSTGKANKITI 503
>gi|194248072 heat shock 70kDa protein 1A [Homo sapiens]
Length = 641
Score = 316 bits (810), Expect = 3e-86
Identities = 178/505 (35%), Positives = 286/505 (56%), Gaps = 7/505 (1%)
Query: 2 AAIGVHLGCTSACVAVYKDGRAGVVANDAGDRVTPAVVAYSENEEIVGLAAKQSRIRNIS 61
AAIG+ LG T +CV V++ G+ ++AND G+R TP+ VA+++ E ++G AAK N
Sbjct: 5 AAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVALNPQ 64
Query: 62 NTVMKVKQILGRSSSDPQAQKYIAESKCLVIEKNGKLRYEIDTGEETKFVNPEDVARLIF 121
NTV K+++GR DP Q + VI K + ++ ETK PE+++ ++
Sbjct: 65 NTVFDAKRLIGRKFGDPVVQSDMKHWPFQVINDGDKPKVQVSYKGETKAFYPEEISSMVL 124
Query: 122 SKMKETAHSVLGSDANDVVITVPFDFGEKQKNALGEAARAAGFNVLRLIHEPSAALLAYG 181
+KMKE A + LG + VITVP F + Q+ A +A AG NVLR+I+EP+AA +AYG
Sbjct: 125 TKMKEIAEAYLGYPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYG 184
Query: 182 IGQDSPTGKSNILVFKLGGTSLSLSVMEVNSGIYRVLSTNTDDNIGGAHFTETLAQYLAS 241
+ + G+ N+L+F LGG + +S++ ++ GI+ V +T D ++GG F L +
Sbjct: 185 LDRTGK-GERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVNHFVE 243
Query: 242 EFQRSFKHDVRGNARAMMKLTNSAEVAKHSLSTLGSANCFLDSLYEGQDFDCNVSRARFE 301
EF+R K D+ N RA+ +L + E AK +LS+ A+ +DSL+EG DF +++RARFE
Sbjct: 244 EFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEIDSLFEGIDFYTSITRARFE 303
Query: 302 LLCSPLFNKCIEAIRGLLDQNGFTADDINKVVLCGGSSRIPKLQQLIKDLFPAVELLNSI 361
LCS LF +E + L I+ +VL GGS+RIPK+Q+L++D F +L SI
Sbjct: 304 ELCSDLFRSTLEPVEKALRDAKLDKAQIHDLVLVGGSTRIPKVQKLLQDFFNGRDLNKSI 363
Query: 362 PPDEVIPIGAAIEAGILIGKENLLVEDSLMIECSARDILVKGVDESGASRFTVLFPSGTP 421
PDE + GAA++A IL+G ++ V+D L+++ + L G++ +G T L +
Sbjct: 364 NPDEAVAYGAAVQAAILMGDKSENVQDLLLLDVAP---LSLGLETAGGV-MTALIKRNST 419
Query: 422 LPARRQHTLQA-PGSISSVCLELYESDGKNSAKEETKFAQVVLQDLDKKENGLRDILAVL 480
+P ++ + V +++YE + + K+ + L + G+ I
Sbjct: 420 IPTKQTQIFTTYSDNQPGVLIQVYEGE-RAMTKDNNLLGRFELSGIPPAPRGVPQIEVTF 478
Query: 481 TMKRDGSLHVTCTDQETGKCEAISI 505
+ +G L+VT TD+ TGK I+I
Sbjct: 479 DIDANGILNVTATDKSTGKANKITI 503
>gi|124256496 heat shock 70kDa protein 1-like [Homo sapiens]
Length = 641
Score = 314 bits (804), Expect = 1e-85
Identities = 177/504 (35%), Positives = 287/504 (56%), Gaps = 7/504 (1%)
Query: 3 AIGVHLGCTSACVAVYKDGRAGVVANDAGDRVTPAVVAYSENEEIVGLAAKQSRIRNISN 62
AIG+ LG T +CV V++ G+ ++AND G+R TP+ VA+++ E ++G AAK N N
Sbjct: 8 AIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPQN 67
Query: 63 TVMKVKQILGRSSSDPQAQKYIAESKCLVIEKNGKLRYEIDTGEETKFVNPEDVARLIFS 122
TV K+++GR +DP Q + VI + GK + + E K PE+++ ++ +
Sbjct: 68 TVFDAKRLIGRKFNDPVVQADMKLWPFQVINEGGKPKVLVSYKGENKAFYPEEISSMVLT 127
Query: 123 KMKETAHSVLGSDANDVVITVPFDFGEKQKNALGEAARAAGFNVLRLIHEPSAALLAYGI 182
K+KETA + LG + VITVP F + Q+ A +A AG NVLR+I+EP+AA +AYG+
Sbjct: 128 KLKETAEAFLGHPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGL 187
Query: 183 GQDSPTGKSNILVFKLGGTSLSLSVMEVNSGIYRVLSTNTDDNIGGAHFTETLAQYLASE 242
+ G+ ++L+F LGG + +S++ ++ GI+ V +T D ++GG F L + E
Sbjct: 188 DKGGQ-GERHVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVSHFVEE 246
Query: 243 FQRSFKHDVRGNARAMMKLTNSAEVAKHSLSTLGSANCFLDSLYEGQDFDCNVSRARFEL 302
F+R K D+ N RA+ +L + E AK +LS+ AN +DSLYEG DF +++RARFE
Sbjct: 247 FKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQANLEIDSLYEGIDFYTSITRARFEE 306
Query: 303 LCSPLFNKCIEAIRGLLDQNGFTADDINKVVLCGGSSRIPKLQQLIKDLFPAVELLNSIP 362
LC+ LF +E + L I+ +VL GGS+RIPK+Q+L++D F +L SI
Sbjct: 307 LCADLFRGTLEPVEKALRDAKMDKAKIHDIVLVGGSTRIPKVQRLLQDYFNGRDLNKSIN 366
Query: 363 PDEVIPIGAAIEAGILIGKENLLVEDSLMIECSARDILVKGVDESGASRFTVLFPSGTPL 422
PDE + GAA++A IL+G ++ V+D L+++ + L G++ +G T L + +
Sbjct: 367 PDEAVAYGAAVQAAILMGDKSEKVQDLLLLDVAP---LSLGLETAGGV-MTALIKRNSTI 422
Query: 423 PARRQHTLQA-PGSISSVCLELYESDGKNSAKEETKFAQVVLQDLDKKENGLRDILAVLT 481
P ++ + V +++YE + + K+ + L + G+ I
Sbjct: 423 PTKQTQIFTTYSDNQPGVLIQVYEGE-RAMTKDNNLLGRFDLTGIPPAPRGVPQIEVTFD 481
Query: 482 MKRDGSLHVTCTDQETGKCEAISI 505
+ +G L+VT TD+ TGK I+I
Sbjct: 482 IDANGILNVTATDKSTGKVNKITI 505
>gi|5729877 heat shock 70kDa protein 8 isoform 1 [Homo sapiens]
Length = 646
Score = 310 bits (795), Expect = 2e-84
Identities = 175/505 (34%), Positives = 287/505 (56%), Gaps = 9/505 (1%)
Query: 3 AIGVHLGCTSACVAVYKDGRAGVVANDAGDRVTPAVVAYSENEEIVGLAAKQSRIRNISN 62
A+G+ LG T +CV V++ G+ ++AND G+R TP+ VA+++ E ++G AAK N +N
Sbjct: 6 AVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTN 65
Query: 63 TVMKVKQILGRSSSDPQAQKYIAESKCLVIEKNGKLRYEIDTGEETKFVNPEDVARLIFS 122
TV K+++GR D Q + +V+ G+ + +++ ETK PE+V+ ++ +
Sbjct: 66 TVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYPEEVSSMVLT 125
Query: 123 KMKETAHSVLGSDANDVVITVPFDFGEKQKNALGEAARAAGFNVLRLIHEPSAALLAYGI 182
KMKE A + LG + V+TVP F + Q+ A +A AG NVLR+I+EP+AA +AYG+
Sbjct: 126 KMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGL 185
Query: 183 GQDSPTG-KSNILVFKLGGTSLSLSVMEVNSGIYRVLSTNTDDNIGGAHFTETLAQYLAS 241
D G + N+L+F LGG + +S++ + GI+ V ST D ++GG F + + +
Sbjct: 186 --DKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNHFIA 243
Query: 242 EFQRSFKHDVRGNARAMMKLTNSAEVAKHSLSTLGSANCFLDSLYEGQDFDCNVSRARFE 301
EF+R K D+ N RA+ +L + E AK +LS+ A+ +DSLYEG DF +++RARFE
Sbjct: 244 EFKRKHKKDISENKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGIDFYTSITRARFE 303
Query: 302 LLCSPLFNKCIEAIRGLLDQNGFTADDINKVVLCGGSSRIPKLQQLIKDLFPAVELLNSI 361
L + LF ++ + L I+ +VL GGS+RIPK+Q+L++D F EL SI
Sbjct: 304 ELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKELNKSI 363
Query: 362 PPDEVIPIGAAIEAGILIGKENLLVEDSLMIECSARDILVKGVDESGASRFTVLFPSGTP 421
PDE + GAA++A IL G ++ V+D L+++ + L G++ +G TVL T
Sbjct: 364 NPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTP---LSLGIETAGGV-MTVLIKRNTT 419
Query: 422 LPARRQHTLQA-PGSISSVCLELYESDGKNSAKEETKFAQVVLQDLDKKENGLRDILAVL 480
+P ++ T + V +++YE + + K+ + L + G+ I
Sbjct: 420 IPTKQTQTFTTYSDNQPGVLIQVYEGE-RAMTKDNNLLGKFELTGIPPAPRGVPQIEVTF 478
Query: 481 TMKRDGSLHVTCTDQETGKCEAISI 505
+ +G L+V+ D+ TGK I+I
Sbjct: 479 DIDANGILNVSAVDKSTGKENKITI 503
>gi|16507237 heat shock 70kDa protein 5 [Homo sapiens]
Length = 654
Score = 307 bits (786), Expect = 2e-83
Identities = 175/505 (34%), Positives = 290/505 (57%), Gaps = 12/505 (2%)
Query: 4 IGVHLGCTSACVAVYKDGRAGVVANDAGDRVTPAVVAYS-ENEEIVGLAAKQSRIRNISN 62
+G+ LG T +CV V+K+GR ++AND G+R+TP+ VA++ E E ++G AAK N N
Sbjct: 31 VGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSNPEN 90
Query: 63 TVMKVKQILGRSSSDPQAQKYIAESKCLVIEKNGKLRYEIDTGE-ETKFVNPEDVARLIF 121
TV K+++GR+ +DP Q+ I V+EK K ++D G +TK PE+++ ++
Sbjct: 91 TVFDAKRLIGRTWNDPSVQQDIKFLPFKVVEKKTKPYIQVDIGGGQTKTFAPEEISAMVL 150
Query: 122 SKMKETAHSVLGSDANDVVITVPFDFGEKQKNALGEAARAAGFNVLRLIHEPSAALLAYG 181
+KMKETA + LG V+TVP F + Q+ A +A AG NV+R+I+EP+AA +AYG
Sbjct: 151 TKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAIAYG 210
Query: 182 IGQDSPTGKSNILVFKLGGTSLSLSVMEVNSGIYRVLSTNTDDNIGGAHFTETLAQYLAS 241
+ D G+ NILVF LGG + +S++ +++G++ V++TN D ++GG F + + ++
Sbjct: 211 L--DKREGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHFIK 268
Query: 242 EFQRSFKHDVRGNARAMMKLTNSAEVAKHSLSTLGSANCFLDSLYEGQDFDCNVSRARFE 301
+++ DVR + RA+ KL E AK +LS+ A ++S YEG+DF ++RA+FE
Sbjct: 269 LYKKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQARIEIESFYEGEDFSETLTRAKFE 328
Query: 302 LLCSPLFNKCIEAIRGLLDQNGFTADDINKVVLCGGSSRIPKLQQLIKDLFPAVELLNSI 361
L LF ++ ++ +L+ + DI+++VL GGS+RIPK+QQL+K+ F E I
Sbjct: 329 ELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIVLVGGSTRIPKIQQLVKEFFNGKEPSRGI 388
Query: 362 PPDEVIPIGAAIEAGILIGKENLLVEDSLMIECSARDILVKGVDESGASRFTVLFPSGTP 421
PDE + GAA++AG+L G ++ D ++++ L G++ G T L P T
Sbjct: 389 NPDEAVAYGAAVQAGVLSGDQD--TGDLVLLDVCP---LTLGIETVGGV-MTKLIPRNTV 442
Query: 422 LPARRQHTLQ-APGSISSVCLELYESDGKNSAKEETKFAQVVLQDLDKKENGLRDILAVL 480
+P ++ A + +V +++YE + + K+ L + G+ I
Sbjct: 443 VPTKKSQIFSTASDNQPTVTIKVYEGE-RPLTKDNHLLGTFDLTGIPPAPRGVPQIEVTF 501
Query: 481 TMKRDGSLHVTCTDQETGKCEAISI 505
+ +G L VT D+ TG I+I
Sbjct: 502 EIDVNGILRVTAEDKGTGNKNKITI 526
>gi|24234686 heat shock 70kDa protein 8 isoform 2 [Homo sapiens]
Length = 493
Score = 296 bits (759), Expect = 2e-80
Identities = 162/447 (36%), Positives = 263/447 (58%), Gaps = 8/447 (1%)
Query: 3 AIGVHLGCTSACVAVYKDGRAGVVANDAGDRVTPAVVAYSENEEIVGLAAKQSRIRNISN 62
A+G+ LG T +CV V++ G+ ++AND G+R TP+ VA+++ E ++G AAK N +N
Sbjct: 6 AVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTN 65
Query: 63 TVMKVKQILGRSSSDPQAQKYIAESKCLVIEKNGKLRYEIDTGEETKFVNPEDVARLIFS 122
TV K+++GR D Q + +V+ G+ + +++ ETK PE+V+ ++ +
Sbjct: 66 TVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYPEEVSSMVLT 125
Query: 123 KMKETAHSVLGSDANDVVITVPFDFGEKQKNALGEAARAAGFNVLRLIHEPSAALLAYGI 182
KMKE A + LG + V+TVP F + Q+ A +A AG NVLR+I+EP+AA +AYG+
Sbjct: 126 KMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGL 185
Query: 183 GQDSPTG-KSNILVFKLGGTSLSLSVMEVNSGIYRVLSTNTDDNIGGAHFTETLAQYLAS 241
D G + N+L+F LGG + +S++ + GI+ V ST D ++GG F + + +
Sbjct: 186 --DKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNHFIA 243
Query: 242 EFQRSFKHDVRGNARAMMKLTNSAEVAKHSLSTLGSANCFLDSLYEGQDFDCNVSRARFE 301
EF+R K D+ N RA+ +L + E AK +LS+ A+ +DSLYEG DF +++RARFE
Sbjct: 244 EFKRKHKKDISENKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGIDFYTSITRARFE 303
Query: 302 LLCSPLFNKCIEAIRGLLDQNGFTADDINKVVLCGGSSRIPKLQQLIKDLFPAVELLNSI 361
L + LF ++ + L I+ +VL GGS+RIPK+Q+L++D F EL SI
Sbjct: 304 ELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKELNKSI 363
Query: 362 PPDEVIPIGAAIEAGILIGKENLLVEDSLMIECSARDILVKGVDESGASRFTVLFPSGTP 421
PDE + GAA++A IL G ++ V+D L+++ + L G++ +G TVL T
Sbjct: 364 NPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTP---LSLGIETAGGV-MTVLIKRNTT 419
Query: 422 LPARRQHTLQA-PGSISSVCLELYESD 447
+P ++ T + V +++YE +
Sbjct: 420 IPTKQTQTFTTYSDNQPGVLIQVYEGE 446
>gi|24234688 heat shock 70kDa protein 9 precursor [Homo sapiens]
Length = 679
Score = 243 bits (619), Expect = 4e-64
Identities = 159/512 (31%), Positives = 264/512 (51%), Gaps = 24/512 (4%)
Query: 2 AAIGVHLGCTSACVAVYKDGRAGVVANDAGDRVTPAVVAYS-ENEEIVGLAAKQSRIRNI 60
A +G+ LG T++CVAV + +A V+ N G R TP+VVA++ + E +VG+ AK+ + N
Sbjct: 54 AVVGIDLGTTNSCVAVMEGKQAKVLENAEGARTTPSVVAFTADGERLVGMPAKRQAVTNP 113
Query: 61 SNTVMKVKQILGRSSSDPQAQKYIAESKCLVIE-KNGKLRYEIDTGEETKFVNPEDVARL 119
+NT K+++GR DP+ QK I ++ NG E K +P +
Sbjct: 114 NNTFYATKRLIGRRYDDPEVQKDIKNVPFKIVRASNGDAWVEA----HGKLYSPSQIGAF 169
Query: 120 IFSKMKETAHSVLGSDANDVVITVPFDFGEKQKNALGEAARAAGFNVLRLIHEPSAALLA 179
+ KMKETA + LG A + VITVP F + Q+ A +A + +G NVLR+I+EP+AA LA
Sbjct: 170 VLMKMKETAENYLGHTAKNAVITVPAYFNDSQRQATKDAGQISGLNVLRVINEPTAAALA 229
Query: 180 YGIGQDSPTGKSNILVFKLGGTSLSLSVMEVNSGIYRVLSTNTDDNIGGAHFTETLAQYL 239
YG+ + I V+ LGG + +S++E+ G++ V STN D +GG F + L +++
Sbjct: 230 YGLDKSE---DKVIAVYDLGGGTFDISILEIQKGVFEVKSTNGDTFLGGEDFDQALLRHI 286
Query: 240 ASEFQRSFKHDVRGNARAMMKLTNSAEVAKHSLSTLGSANCFLDSLYEG----QDFDCNV 295
EF+R D+ + A+ ++ +AE AK LS+ + L L + + +
Sbjct: 287 VKEFKRETGVDLTKDNMALQRVREAAEKAKCELSSSVQTDINLPYLTMDSSGPKHLNMKL 346
Query: 296 SRARFELLCSPLFNKCIEAIRGLLDQNGFTADDINKVVLCGGSSRIPKLQQLIKDLFPAV 355
+RA+FE + + L + I + + + DI +V+L GG +R+PK+QQ ++DLF
Sbjct: 347 TRAQFEGIVTDLIRRTIAPCQKAMQDAEVSKSDIGEVILVGGMTRMPKVQQTVQDLFGRA 406
Query: 356 ELLNSIPPDEVIPIGAAIEAGILIGKENLLVEDSLMIECSARDILVKGVDESGASRFTVL 415
++ PDE + IGAAI+ G+L G V D L+++ + L G++ G FT L
Sbjct: 407 P-SKAVNPDEAVAIGAAIQGGVLAGD----VTDVLLLDVTP---LSLGIETLGGV-FTKL 457
Query: 416 FPSGTPLPARRQHTLQAPGSISSVCLELYESDGKNSAKEETK-FAQVVLQDLDKKENGLR 474
T +P ++ +E+ G+ + K Q L + G+
Sbjct: 458 INRNTTIPTKKSQVFSTAAD-GQTQVEIKVCQGEREMAGDNKLLGQFTLIGIPPAPRGVP 516
Query: 475 DILAVLTMKRDGSLHVTCTDQETGKCEAISIE 506
I + +G +HV+ D+ TG+ + I I+
Sbjct: 517 QIEVTFDIDANGIVHVSAKDKGTGREQQIVIQ 548
>gi|42544159 heat shock 105kD [Homo sapiens]
Length = 858
Score = 192 bits (489), Expect = 5e-49
Identities = 137/485 (28%), Positives = 240/485 (49%), Gaps = 25/485 (5%)
Query: 1 MAAIGVHLGCTSACVAVYKDGRAGVVANDAGDRVTPAVVAYSENEEIVGLAAKQSRIRNI 60
M+ +G+ +G S +AV + G +AN+ DR TP+V+++ +G+AAK +I +
Sbjct: 1 MSVVGLDVGSQSCYIAVARAGGIETIANEFSDRCTPSVISFGSKNRTIGVAAKNQQITHA 60
Query: 61 SNTVMKVKQILGRSSSDPQAQKYIAE-SKCLVIEKNGKLRYEIDTGEETKFVNPEDVARL 119
+NTV K+ GR+ +DP QK S LV KNG + ++ E + E + +
Sbjct: 61 NNTVSNFKRFHGRAFNDPFIQKEKENLSYDLVPLKNGGVGIKVMYMGEEHLFSVEQITAM 120
Query: 120 IFSKMKETAHSVLGSDANDVVITVPFDFGEKQKNALGEAARAAGFNVLRLIHEPSAALLA 179
+ +K+KETA + L D VI+VP F + ++ ++ +AA+ G N LRL+++ +A L
Sbjct: 121 LLTKLKETAENSLKKPVTDCVISVPSFFTDAERRSVLDAAQIVGLNCLRLMNDMTAVALN 180
Query: 180 YGI-GQDSPT--GKSNILVF-KLGGTSLSLSVMEVNSGIYRVLSTNTDDNIGGAHFTETL 235
YGI QD P+ K I+VF +G ++ +S N G +VL T D +GG +F E L
Sbjct: 181 YGIYKQDLPSLDEKPRIVVFVDMGHSAFQVSACAFNKGKLKVLGTAFDPFLGGKNFDEKL 240
Query: 236 AQYLASEFQRSFKHDVRGNARAMMKLTNSAEVAKHSLSTLG-----SANCFLDSLYEGQD 290
++ +EF+ +K D + RA+++L E K +S+ + CF++ +D
Sbjct: 241 VEHFCAEFKTKYKLDAKSKIRALLRLYQECEKLKKLMSSNSTDLPLNIECFMND----KD 296
Query: 291 FDCNVSRARFELLCSPLFNKCIEAIRGLLDQNGFTADDINKVVLCGGSSRIPKLQQLIKD 350
++R++FE LC+ L K + LL+Q +D++ V + GG++RIP +++ I
Sbjct: 297 VSGKMNRSQFEELCAELLQKIEVPLYSLLEQTHLKVEDVSAVEIVGGATRIPAVKERIAK 356
Query: 351 LFPAVELLNSIPPDEVIPIGAAIEAGIL---IGKENLLVEDSLMIECSARDILVKGVDES 407
F ++ ++ DE + G A++ IL V D++ S L+ D
Sbjct: 357 FF-GKDISTTLNADEAVARGCALQCAILSPAFKVREFSVTDAVPFPIS----LIWNHDSE 411
Query: 408 GASRFTVLFPSGTPLPARRQHTLQAPGSISSVCLELYESDGKNSAKEETKFAQVVLQDLD 467
+F P + T G LE + SD + E K + V+Q++
Sbjct: 412 DTEGVHEVFSRNHAAPFSKVLTFLRRGPFE---LEAFYSDPQGVPYPEAKIGRFVVQNVS 468
Query: 468 KKENG 472
+++G
Sbjct: 469 AQKDG 473
>gi|38327039 heat shock 70kDa protein 4 [Homo sapiens]
Length = 840
Score = 191 bits (485), Expect = 1e-48
Identities = 123/391 (31%), Positives = 200/391 (51%), Gaps = 21/391 (5%)
Query: 1 MAAIGVHLGCTSACVAVYKDGRAGVVANDAGDRVTPAVVAYSENEEIVGLAAKQSRIRNI 60
M+ +G+ LG S VAV + G +AN+ DR TPA +++ +G AAK I N
Sbjct: 1 MSVVGIDLGFQSCYVAVARAGGIETIANEYSDRCTPACISFGPKNRSIGAAAKSQVISNA 60
Query: 61 SNTVMKVKQILGRSSSDPQAQKYIAESKCLVIE----KNGKLRYEIDTGEETKFVNPEDV 116
NTV K+ GR+ SDP + AE L + G ++ EE + E V
Sbjct: 61 KNTVQGFKRFHGRAFSDPFVE---AEKSNLAYDIVQLPTGLTGIKVTYMEEERNFTTEQV 117
Query: 117 ARLIFSKMKETAHSVLGSDANDVVITVPFDFGEKQKNALGEAARAAGFNVLRLIHEPSAA 176
++ SK+KETA SVL D V++VP + + ++ ++ +A + AG N LRL++E +A
Sbjct: 118 TAMLLSKLKETAESVLKKPVVDCVVSVPCFYTDAERRSVMDATQIAGLNCLRLMNETTAV 177
Query: 177 LLAYGI-GQDSPTGKS---NILVFKLGGTSLSLSVMEVNSGIYRVLSTNTDDNIGGAHFT 232
LAYGI QD P + N++ +G ++ +SV N G +VL+T D +GG F
Sbjct: 178 ALAYGIYKQDLPALEEKPRNVVFVDMGHSAYQVSVCAFNRGKLKVLATAFDTTLGGRKFD 237
Query: 233 ETLAQYLASEFQRSFKHDVRGNARAMMKLTNSAEVAKHSLSTLG-----SANCFLDSLYE 287
E L + EF + +K D++ RA+++L+ E K +S S CF++ +
Sbjct: 238 EVLVNHFCEEFGKKYKLDIKSKIRALLRLSQECEKLKKLMSANASDLPLSIECFMNDV-- 295
Query: 288 GQDFDCNVSRARFELLCSPLFNKCIEAIRGLLDQNGFTADDINKVVLCGGSSRIPKLQQL 347
D ++R +F +C+ L + +R +L+Q +DI V + GG++RIP +++
Sbjct: 296 --DVSGTMNRGKFLEMCNDLLARVEPPLRSVLEQTKLKKEDIYAVEIVGGATRIPAVKEK 353
Query: 348 IKDLFPAVELLNSIPPDEVIPIGAAIEAGIL 378
I F EL ++ DE + G A++ IL
Sbjct: 354 ISKFF-GKELSTTLNADEAVTRGCALQCAIL 383
>gi|31541941 heat shock 70kDa protein 4-like [Homo sapiens]
Length = 839
Score = 189 bits (479), Expect = 7e-48
Identities = 118/388 (30%), Positives = 202/388 (52%), Gaps = 15/388 (3%)
Query: 1 MAAIGVHLGCTSACVAVYKDGRAGVVANDAGDRVTPAVVAYSENEEIVGLAAKQSRIRNI 60
M+ +G+ LG + +AV + G +AN+ DR TPA ++ +G AAK + N+
Sbjct: 1 MSVVGIDLGFLNCYIAVARSGGIETIANEYSDRCTPACISLGSRTRAIGNAAKSQIVTNV 60
Query: 61 SNTVMKVKQILGRSSSDPQAQ-KYIAESKCLVIEKNGKLRYEIDTGEETKFVNPEDVARL 119
NT+ K++ GRS DP Q + I L NG ++ EE + E V +
Sbjct: 61 RNTIHGFKKLHGRSFDDPIVQTERIRLPYELQKMPNGSAGVKVRYLEEERPFAIEQVTGM 120
Query: 120 IFSKMKETAHSVLGSDANDVVITVPFDFGEKQKNALGEAARAAGFNVLRLIHEPSAALLA 179
+ +K+KET+ + L D VI++P F + ++ ++ AA+ AG N LRL++E +A LA
Sbjct: 121 LLAKLKETSENALKKPVADCVISIPSFFTDAERRSVMAAAQVAGLNCLRLMNETTAVALA 180
Query: 180 YGI-GQDSP---TGKSNILVFKLGGTSLSLSVMEVNSGIYRVLSTNTDDNIGGAHFTETL 235
YGI QD P N++ +G ++ + V N G +VL+T D +GG +F E L
Sbjct: 181 YGIYKQDLPPLDEKPRNVVFIDMGHSAYQVLVCAFNKGKLKVLATTFDPYLGGRNFDEAL 240
Query: 236 AQYLASEFQRSFKHDVRGNARAMMKLTNSAEVAKHSLSTLGS-----ANCFLDSLYEGQD 290
Y EF+ +K +V+ N+RA+++L E K +S S CF++ L D
Sbjct: 241 VDYFCDEFKTKYKINVKENSRALLRLYQECEKLKKLMSANASDLPLNIECFMNDL----D 296
Query: 291 FDCNVSRARFELLCSPLFNKCIEAIRGLLDQNGFTADDINKVVLCGGSSRIPKLQQLIKD 350
++RA+FE LC+ L + ++ +++Q +DI+ + + GG++RIP +++ I
Sbjct: 297 VSSKMNRAQFEQLCASLLARVEPPLKAVMEQANLQREDISSIEIVGGATRIPAVKEQITK 356
Query: 351 LFPAVELLNSIPPDEVIPIGAAIEAGIL 378
F ++ ++ DE + G A++ IL
Sbjct: 357 FF-LKDISTTLNADEAVARGCALQCAIL 383
>gi|48928056 heat shock protein 70kDa family member 13 precursor
[Homo sapiens]
Length = 471
Score = 170 bits (430), Expect = 3e-42
Identities = 118/419 (28%), Positives = 206/419 (49%), Gaps = 51/419 (12%)
Query: 4 IGVHLGCTSACVAVY--KDGRAGVVANDAGDRVTPAVVAYSENEEIVGLAAKQSRIRNIS 61
IG+ LG T V V+ G+ V+ ++ G P++V++++N+ VG + + N
Sbjct: 34 IGIDLGTTYCSVGVFFPGTGKVKVIPDENGHISIPSMVSFTDNDVYVGYESVELADSNPQ 93
Query: 62 NTVMKVKQILGRSSSDPQAQKYIAESKCLVIEKNGKLRYEIDTGEETKFVNPEDVARLIF 121
NT+ K+ +G+ + + + I V+ KNG + + + T ET V+PE V +
Sbjct: 94 NTIYDAKRFIGKIFTAEELEAEIGRYPFKVLNKNGMVEFSV-TSNETITVSPEYVGSRLL 152
Query: 122 SKMKETAHSVLGSDANDVVITVPFDFGEKQKNALGEAARAAGFNVLRLIHEPSAALLAYG 181
K+KE A + LG + VI+VP +F KQ+N+ EAA AG +LR+I+EP+AA +AYG
Sbjct: 153 LKLKEMAEAYLGMPVANAVISVPAEFDLKQRNSTIEAANLAGLKILRVINEPTAAAMAYG 212
Query: 182 IGQDSPTGKSNILVFKLGGTSLSLSVMEVNSGIYRVLSTNTDDNIGGAHFTETLAQYLAS 241
+ + ++LV LGG +L +S++ G++ + + ++ +GG F + L QYL
Sbjct: 213 LHK---ADVFHVLVIDLGGGTLDVSLLNKQGGMFLTRAMSGNNKLGGQDFNQRLLQYLYK 269
Query: 242 EFQRSFKHDVRGNARAMMKLTNSAEVAKHSLSTLGSANCFLDSLYEGQD----------- 290
+ +++ V + +L + E+ K +L+ SA + E QD
Sbjct: 270 QIYQTYGF-VPSRKEEIHRLRQAVEMVKLNLTLHQSAQLSVLLTVEEQDRKEPHSSDTEL 328
Query: 291 --------------------------------FDCNVSRARFELLCSPLFNKCIEAIRGL 318
F+ +SR F+ L LF K + I+ +
Sbjct: 329 PKDKLSSADDHRVNSGFGRGLSDKKSGESQVLFETEISRKLFDTLNEDLFQKILVPIQQV 388
Query: 319 LDQNGFTADDINKVVLCGGSSRIPKLQQLIKDLFPAVELLNSIPPDEVIPIGAAIEAGI 377
L + +I++VVL GGS+RIP+++Q+I++ F + S+ PD + G AI+AGI
Sbjct: 389 LKEGHLEKTEIDEVVLVGGSTRIPRIRQVIQEFF-GKDPNTSVDPDLAVVTGVAIQAGI 446
>gi|195976805 hypoxia up-regulated 1 precursor [Homo sapiens]
Length = 999
Score = 154 bits (388), Expect = 2e-37
Identities = 114/397 (28%), Positives = 188/397 (47%), Gaps = 22/397 (5%)
Query: 1 MAAIGVHLGCTSACVAVYKDG-RAGVVANDAGDRVTPAVVAYSENEEIVGLAAKQSRIRN 59
+A + V LG S VA+ K G +V N R TP +V ENE G +A I+N
Sbjct: 33 LAVMSVDLGSESMKVAIVKPGVPMEIVLNKESRRKTPVIVTLKENERFFGDSAASMAIKN 92
Query: 60 ISNTVMKVKQILGRSSSDPQAQKYIA---ESKCLVIEKNGKLRYEIDTGEETKFVNPEDV 116
T+ + +LG+ + +P Y A E + + + ++I + + +F +PE+V
Sbjct: 93 PKATLRYFQHLLGKQADNPHVALYQARFPEHELTFDPQRQTVHFQISS--QLQF-SPEEV 149
Query: 117 ARLIFSKMKETAHSVLGSDANDVVITVPFDFGEKQKNALGEAARAAGFNVLRLIHEPSAA 176
++ + + A D VITVP F + ++ A+ +AAR AG VL+LI++ +A
Sbjct: 150 LGMVLNYSRSLAEDFAEQPIKDAVITVPVFFNQAERRAVLQAARMAGLKVLQLINDNTAT 209
Query: 177 LLAYGI--GQDSPTGKSNILVFKLGGTSLSLSVMEVN------SGIY---RVLSTNTDDN 225
L+YG+ +D T NI+ + +G S +++ +G+ ++ D
Sbjct: 210 ALSYGVFRRKDINTTAQNIMFYDMGSGSTVCTIVTYQMVKTKEAGMQPQLQIRGVGFDRT 269
Query: 226 IGGAHFTETLAQYLASEFQRSFK----HDVRGNARAMMKLTNSAEVAKHSLSTLGSANCF 281
+GG L + LA F K DVR N RAM KL A K LS
Sbjct: 270 LGGLEMELRLRERLAGLFNEQRKGQRAKDVRENPRAMAKLLREANRLKTVLSANADHMAQ 329
Query: 282 LDSLYEGQDFDCNVSRARFELLCSPLFNKCIEAIRGLLDQNGFTADDINKVVLCGGSSRI 341
++ L + DF V+R FE LC+ LF + ++ L + D+I +V+L GG++R+
Sbjct: 330 IEGLMDDVDFKAKVTRVEFEELCADLFERVPGPVQQALQSAEMSLDEIEQVILVGGATRV 389
Query: 342 PKLQQLIKDLFPAVELLNSIPPDEVIPIGAAIEAGIL 378
P++Q+++ EL +I DE +GA +A L
Sbjct: 390 PRVQEVLLKAVGKEELGKNINADEAAAMGAVYQAAAL 426
>gi|5453832 hypoxia up-regulated 1 precursor [Homo sapiens]
Length = 999
Score = 154 bits (388), Expect = 2e-37
Identities = 114/397 (28%), Positives = 188/397 (47%), Gaps = 22/397 (5%)
Query: 1 MAAIGVHLGCTSACVAVYKDG-RAGVVANDAGDRVTPAVVAYSENEEIVGLAAKQSRIRN 59
+A + V LG S VA+ K G +V N R TP +V ENE G +A I+N
Sbjct: 33 LAVMSVDLGSESMKVAIVKPGVPMEIVLNKESRRKTPVIVTLKENERFFGDSAASMAIKN 92
Query: 60 ISNTVMKVKQILGRSSSDPQAQKYIA---ESKCLVIEKNGKLRYEIDTGEETKFVNPEDV 116
T+ + +LG+ + +P Y A E + + + ++I + + +F +PE+V
Sbjct: 93 PKATLRYFQHLLGKQADNPHVALYQARFPEHELTFDPQRQTVHFQISS--QLQF-SPEEV 149
Query: 117 ARLIFSKMKETAHSVLGSDANDVVITVPFDFGEKQKNALGEAARAAGFNVLRLIHEPSAA 176
++ + + A D VITVP F + ++ A+ +AAR AG VL+LI++ +A
Sbjct: 150 LGMVLNYSRSLAEDFAEQPIKDAVITVPVFFNQAERRAVLQAARMAGLKVLQLINDNTAT 209
Query: 177 LLAYGI--GQDSPTGKSNILVFKLGGTSLSLSVMEVN------SGIY---RVLSTNTDDN 225
L+YG+ +D T NI+ + +G S +++ +G+ ++ D
Sbjct: 210 ALSYGVFRRKDINTTAQNIMFYDMGSGSTVCTIVTYQMVKTKEAGMQPQLQIRGVGFDRT 269
Query: 226 IGGAHFTETLAQYLASEFQRSFK----HDVRGNARAMMKLTNSAEVAKHSLSTLGSANCF 281
+GG L + LA F K DVR N RAM KL A K LS
Sbjct: 270 LGGLEMELRLRERLAGLFNEQRKGQRAKDVRENPRAMAKLLREANRLKTVLSANADHMAQ 329
Query: 282 LDSLYEGQDFDCNVSRARFELLCSPLFNKCIEAIRGLLDQNGFTADDINKVVLCGGSSRI 341
++ L + DF V+R FE LC+ LF + ++ L + D+I +V+L GG++R+
Sbjct: 330 IEGLMDDVDFKAKVTRVEFEELCADLFERVPGPVQQALQSAEMSLDEIEQVILVGGATRV 389
Query: 342 PKLQQLIKDLFPAVELLNSIPPDEVIPIGAAIEAGIL 378
P++Q+++ EL +I DE +GA +A L
Sbjct: 390 PRVQEVLLKAVGKEELGKNINADEAAAMGAVYQAAAL 426
>gi|48527957 galactokinase 2 isoform 2 [Homo sapiens]
Length = 447
Score = 30.4 bits (67), Expect = 4.0
Identities = 16/53 (30%), Positives = 27/53 (50%), Gaps = 3/53 (5%)
Query: 112 NPEDVARLIFSKMKETAHSVLGSDANDVVITVPFDFGEKQKNALGEAARAAGF 164
NPE++ R + ++E +L + DV+I F ++ K+ EAAR F
Sbjct: 285 NPEEICRCLGISLEELRTQILSPNTQDVLI---FKLYQRAKHVYSEAARVLQF 334
>gi|4503897 galactokinase 2 isoform 1 [Homo sapiens]
Length = 458
Score = 30.4 bits (67), Expect = 4.0
Identities = 16/53 (30%), Positives = 27/53 (50%), Gaps = 3/53 (5%)
Query: 112 NPEDVARLIFSKMKETAHSVLGSDANDVVITVPFDFGEKQKNALGEAARAAGF 164
NPE++ R + ++E +L + DV+I F ++ K+ EAAR F
Sbjct: 296 NPEEICRCLGISLEELRTQILSPNTQDVLI---FKLYQRAKHVYSEAARVLQF 345
>gi|226958575 RAS protein activator like 2 isoform 2 [Homo sapiens]
Length = 1280
Score = 30.0 bits (66), Expect = 5.2
Identities = 18/57 (31%), Positives = 31/57 (54%), Gaps = 6/57 (10%)
Query: 350 DLFPAVELLNSIPP---DEVIPIGAAIEAGILIGKENLLVEDSLMIECSARDILVKG 403
++FPA+E + +PP D V+P+ A+ G+L + +L+E + R VKG
Sbjct: 18 EMFPALESDSPLPPEDLDAVVPVSGAVAGGML---DRILLESVCQQQSWVRVYDVKG 71
>gi|4506889 mitogen-activated protein kinase kinase 4 [Homo sapiens]
Length = 399
Score = 29.3 bits (64), Expect = 8.9
Identities = 18/68 (26%), Positives = 32/68 (47%), Gaps = 2/68 (2%)
Query: 112 NPEDVARLIFSKMKETAHSVLGSDANDVVITVPFDFGEKQKNALGEAARAAGFNVLRLIH 171
NP V +++ HS+ S + +DF + LGE R A +V +++H
Sbjct: 64 NPTGVQNPHIERLR--THSIESSGKLKISPEQHWDFTAEDLKDLGEIGRGAYGSVNKMVH 121
Query: 172 EPSAALLA 179
+PS ++A
Sbjct: 122 KPSGQIMA 129
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.133 0.372
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,811,325
Number of Sequences: 37866
Number of extensions: 761496
Number of successful extensions: 1999
Number of sequences better than 10.0: 20
Number of HSP's better than 10.0 without gapping: 16
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 1945
Number of HSP's gapped (non-prelim): 22
length of query: 509
length of database: 18,247,518
effective HSP length: 107
effective length of query: 402
effective length of database: 14,195,856
effective search space: 5706734112
effective search space used: 5706734112
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.