Guide to the Human Genome
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Search of human proteins with 82659091

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|82659091 staufen isoform c [Homo sapiens]
         (502 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|82659091 staufen isoform c [Homo sapiens]                         1011   0.0  
gi|82659089 staufen isoform a [Homo sapiens]                          992   0.0  
gi|82659087 staufen isoform b [Homo sapiens]                          992   0.0  
gi|82659085 staufen isoform a [Homo sapiens]                          992   0.0  
gi|82659083 staufen isoform a [Homo sapiens]                          992   0.0  
gi|7657625 staufen homolog 2 [Homo sapiens]                           364   e-100
gi|19743838 TAR RNA binding protein 2 isoform b [Homo sapiens]         77   4e-14
gi|19743840 TAR RNA binding protein 2 isoform a [Homo sapiens]         77   4e-14
gi|85068512 TAR RNA binding protein 2 isoform b [Homo sapiens]         77   4e-14
gi|213417919 protein kinase, interferon-inducible double strande...    69   1e-11
gi|213417911 protein kinase, interferon-inducible double strande...    69   1e-11
gi|4505581 protein kinase, interferon-inducible double stranded ...    69   1e-11
gi|24234756 interleukin enhancer binding factor 3 isoform c [Hom...    57   3e-08
gi|24234753 interleukin enhancer binding factor 3 isoform b [Hom...    57   3e-08
gi|24234750 interleukin enhancer binding factor 3 isoform a [Hom...    57   3e-08
gi|212549555 interleukin enhancer binding factor 3 isoform e [Ho...    57   4e-08
gi|212549553 interleukin enhancer binding factor 3 isoform d [Ho...    57   4e-08
gi|237681091 RNA-specific adenosine deaminase B1 isoform 7 [Homo...    56   7e-08
gi|7669479 RNA-specific adenosine deaminase B1 isoform 3 [Homo s...    56   7e-08
gi|7669477 RNA-specific adenosine deaminase B1 isoform 2 [Homo s...    56   7e-08
gi|4501919 RNA-specific adenosine deaminase B1 isoform 1 [Homo s...    56   7e-08
gi|21361745 spermatid perinuclear RNA binding protein [Homo sapi...    55   1e-07
gi|208431829 eukaryotic translation initiation factor 2-alpha ki...    44   3e-04
gi|208431827 eukaryotic translation initiation factor 2-alpha ki...    44   3e-04
gi|4506103 eukaryotic translation initiation factor 2-alpha kina...    44   3e-04
gi|8922077 adenosine deaminase, RNA-specific, B2 [Homo sapiens]        42   0.001
gi|70167032 adenosine deaminase, RNA-specific isoform c [Homo sa...    40   0.006
gi|70167113 adenosine deaminase, RNA-specific isoform d [Homo sa...    39   0.014
gi|70166944 adenosine deaminase, RNA-specific isoform b [Homo sa...    39   0.014
gi|70166852 adenosine deaminase, RNA-specific isoform a [Homo sa...    39   0.014

>gi|82659091 staufen isoform c [Homo sapiens]
          Length = 502

 Score = 1011 bits (2613), Expect = 0.0
 Identities = 502/502 (100%), Positives = 502/502 (100%)

Query: 1   MKLGKKPMYKPVDPYSRMQSTYNYNMRGGAYPPRYFYPFPVPPLLYQVELSVGGQQFNGK 60
           MKLGKKPMYKPVDPYSRMQSTYNYNMRGGAYPPRYFYPFPVPPLLYQVELSVGGQQFNGK
Sbjct: 1   MKLGKKPMYKPVDPYSRMQSTYNYNMRGGAYPPRYFYPFPVPPLLYQVELSVGGQQFNGK 60

Query: 61  GKTRQAAKHDAAAKALRILQNEPLPERLEVNGRESEEENLNKSEISQVFEIALKRNLPVN 120
           GKTRQAAKHDAAAKALRILQNEPLPERLEVNGRESEEENLNKSEISQVFEIALKRNLPVN
Sbjct: 61  GKTRQAAKHDAAAKALRILQNEPLPERLEVNGRESEEENLNKSEISQVFEIALKRNLPVN 120

Query: 121 FESFPLKQVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLPPL 180
           FESFPLKQVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLPPL
Sbjct: 121 FESFPLKQVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLPPL 180

Query: 181 PAVERVKPRIKKKTKPIVKPQTSPEYGQGINPISRLAQIQQAKKEKEPEYTLLTERGLPR 240
           PAVERVKPRIKKKTKPIVKPQTSPEYGQGINPISRLAQIQQAKKEKEPEYTLLTERGLPR
Sbjct: 181 PAVERVKPRIKKKTKPIVKPQTSPEYGQGINPISRLAQIQQAKKEKEPEYTLLTERGLPR 240

Query: 241 RREFVMQVKVGNHTAEGTGTNKKVAKRNAAENMLEILGFKVPQAQPTKPALKSEEKTPIK 300
           RREFVMQVKVGNHTAEGTGTNKKVAKRNAAENMLEILGFKVPQAQPTKPALKSEEKTPIK
Sbjct: 241 RREFVMQVKVGNHTAEGTGTNKKVAKRNAAENMLEILGFKVPQAQPTKPALKSEEKTPIK 300

Query: 301 KPGDGRKVTFFEPGSGDENGTSNKEDEFRMPYLSHQQLPAGILPMVPEVAQAVGVSQGHH 360
           KPGDGRKVTFFEPGSGDENGTSNKEDEFRMPYLSHQQLPAGILPMVPEVAQAVGVSQGHH
Sbjct: 301 KPGDGRKVTFFEPGSGDENGTSNKEDEFRMPYLSHQQLPAGILPMVPEVAQAVGVSQGHH 360

Query: 361 TKDFTRAAPNPAKATVTAMIARELLYGGTSPTAETILKNNISSGHVPHGPLTRPSEQLDY 420
           TKDFTRAAPNPAKATVTAMIARELLYGGTSPTAETILKNNISSGHVPHGPLTRPSEQLDY
Sbjct: 361 TKDFTRAAPNPAKATVTAMIARELLYGGTSPTAETILKNNISSGHVPHGPLTRPSEQLDY 420

Query: 421 LSRVQGFQVEYKDFPKNNKNEFVSLINCSSQPPLISHGIGKDVESCHDMAALNILKLLSE 480
           LSRVQGFQVEYKDFPKNNKNEFVSLINCSSQPPLISHGIGKDVESCHDMAALNILKLLSE
Sbjct: 421 LSRVQGFQVEYKDFPKNNKNEFVSLINCSSQPPLISHGIGKDVESCHDMAALNILKLLSE 480

Query: 481 LDQQSTEMPRTGNGPMSVCGRC 502
           LDQQSTEMPRTGNGPMSVCGRC
Sbjct: 481 LDQQSTEMPRTGNGPMSVCGRC 502


>gi|82659089 staufen isoform a [Homo sapiens]
          Length = 496

 Score =  992 bits (2565), Expect = 0.0
 Identities = 496/502 (98%), Positives = 496/502 (98%), Gaps = 6/502 (1%)

Query: 1   MKLGKKPMYKPVDPYSRMQSTYNYNMRGGAYPPRYFYPFPVPPLLYQVELSVGGQQFNGK 60
           MKLGKKPMYKPVDPYSRMQSTYNYNMRGGAYPPRYFYPFPVPPLLYQVELSVGGQQFNGK
Sbjct: 1   MKLGKKPMYKPVDPYSRMQSTYNYNMRGGAYPPRYFYPFPVPPLLYQVELSVGGQQFNGK 60

Query: 61  GKTRQAAKHDAAAKALRILQNEPLPERLEVNGRESEEENLNKSEISQVFEIALKRNLPVN 120
           GKTRQAAKHDAAAKALRILQNEPLPERLEVNGRESEEENLNKSEISQVFEIALKRNLPVN
Sbjct: 61  GKTRQAAKHDAAAKALRILQNEPLPERLEVNGRESEEENLNKSEISQVFEIALKRNLPVN 120

Query: 121 FESFPLKQVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLPPL 180
           FE      VARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLPPL
Sbjct: 121 FE------VARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLPPL 174

Query: 181 PAVERVKPRIKKKTKPIVKPQTSPEYGQGINPISRLAQIQQAKKEKEPEYTLLTERGLPR 240
           PAVERVKPRIKKKTKPIVKPQTSPEYGQGINPISRLAQIQQAKKEKEPEYTLLTERGLPR
Sbjct: 175 PAVERVKPRIKKKTKPIVKPQTSPEYGQGINPISRLAQIQQAKKEKEPEYTLLTERGLPR 234

Query: 241 RREFVMQVKVGNHTAEGTGTNKKVAKRNAAENMLEILGFKVPQAQPTKPALKSEEKTPIK 300
           RREFVMQVKVGNHTAEGTGTNKKVAKRNAAENMLEILGFKVPQAQPTKPALKSEEKTPIK
Sbjct: 235 RREFVMQVKVGNHTAEGTGTNKKVAKRNAAENMLEILGFKVPQAQPTKPALKSEEKTPIK 294

Query: 301 KPGDGRKVTFFEPGSGDENGTSNKEDEFRMPYLSHQQLPAGILPMVPEVAQAVGVSQGHH 360
           KPGDGRKVTFFEPGSGDENGTSNKEDEFRMPYLSHQQLPAGILPMVPEVAQAVGVSQGHH
Sbjct: 295 KPGDGRKVTFFEPGSGDENGTSNKEDEFRMPYLSHQQLPAGILPMVPEVAQAVGVSQGHH 354

Query: 361 TKDFTRAAPNPAKATVTAMIARELLYGGTSPTAETILKNNISSGHVPHGPLTRPSEQLDY 420
           TKDFTRAAPNPAKATVTAMIARELLYGGTSPTAETILKNNISSGHVPHGPLTRPSEQLDY
Sbjct: 355 TKDFTRAAPNPAKATVTAMIARELLYGGTSPTAETILKNNISSGHVPHGPLTRPSEQLDY 414

Query: 421 LSRVQGFQVEYKDFPKNNKNEFVSLINCSSQPPLISHGIGKDVESCHDMAALNILKLLSE 480
           LSRVQGFQVEYKDFPKNNKNEFVSLINCSSQPPLISHGIGKDVESCHDMAALNILKLLSE
Sbjct: 415 LSRVQGFQVEYKDFPKNNKNEFVSLINCSSQPPLISHGIGKDVESCHDMAALNILKLLSE 474

Query: 481 LDQQSTEMPRTGNGPMSVCGRC 502
           LDQQSTEMPRTGNGPMSVCGRC
Sbjct: 475 LDQQSTEMPRTGNGPMSVCGRC 496


>gi|82659087 staufen isoform b [Homo sapiens]
          Length = 577

 Score =  992 bits (2565), Expect = 0.0
 Identities = 496/502 (98%), Positives = 496/502 (98%), Gaps = 6/502 (1%)

Query: 1   MKLGKKPMYKPVDPYSRMQSTYNYNMRGGAYPPRYFYPFPVPPLLYQVELSVGGQQFNGK 60
           MKLGKKPMYKPVDPYSRMQSTYNYNMRGGAYPPRYFYPFPVPPLLYQVELSVGGQQFNGK
Sbjct: 82  MKLGKKPMYKPVDPYSRMQSTYNYNMRGGAYPPRYFYPFPVPPLLYQVELSVGGQQFNGK 141

Query: 61  GKTRQAAKHDAAAKALRILQNEPLPERLEVNGRESEEENLNKSEISQVFEIALKRNLPVN 120
           GKTRQAAKHDAAAKALRILQNEPLPERLEVNGRESEEENLNKSEISQVFEIALKRNLPVN
Sbjct: 142 GKTRQAAKHDAAAKALRILQNEPLPERLEVNGRESEEENLNKSEISQVFEIALKRNLPVN 201

Query: 121 FESFPLKQVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLPPL 180
           FE      VARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLPPL
Sbjct: 202 FE------VARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLPPL 255

Query: 181 PAVERVKPRIKKKTKPIVKPQTSPEYGQGINPISRLAQIQQAKKEKEPEYTLLTERGLPR 240
           PAVERVKPRIKKKTKPIVKPQTSPEYGQGINPISRLAQIQQAKKEKEPEYTLLTERGLPR
Sbjct: 256 PAVERVKPRIKKKTKPIVKPQTSPEYGQGINPISRLAQIQQAKKEKEPEYTLLTERGLPR 315

Query: 241 RREFVMQVKVGNHTAEGTGTNKKVAKRNAAENMLEILGFKVPQAQPTKPALKSEEKTPIK 300
           RREFVMQVKVGNHTAEGTGTNKKVAKRNAAENMLEILGFKVPQAQPTKPALKSEEKTPIK
Sbjct: 316 RREFVMQVKVGNHTAEGTGTNKKVAKRNAAENMLEILGFKVPQAQPTKPALKSEEKTPIK 375

Query: 301 KPGDGRKVTFFEPGSGDENGTSNKEDEFRMPYLSHQQLPAGILPMVPEVAQAVGVSQGHH 360
           KPGDGRKVTFFEPGSGDENGTSNKEDEFRMPYLSHQQLPAGILPMVPEVAQAVGVSQGHH
Sbjct: 376 KPGDGRKVTFFEPGSGDENGTSNKEDEFRMPYLSHQQLPAGILPMVPEVAQAVGVSQGHH 435

Query: 361 TKDFTRAAPNPAKATVTAMIARELLYGGTSPTAETILKNNISSGHVPHGPLTRPSEQLDY 420
           TKDFTRAAPNPAKATVTAMIARELLYGGTSPTAETILKNNISSGHVPHGPLTRPSEQLDY
Sbjct: 436 TKDFTRAAPNPAKATVTAMIARELLYGGTSPTAETILKNNISSGHVPHGPLTRPSEQLDY 495

Query: 421 LSRVQGFQVEYKDFPKNNKNEFVSLINCSSQPPLISHGIGKDVESCHDMAALNILKLLSE 480
           LSRVQGFQVEYKDFPKNNKNEFVSLINCSSQPPLISHGIGKDVESCHDMAALNILKLLSE
Sbjct: 496 LSRVQGFQVEYKDFPKNNKNEFVSLINCSSQPPLISHGIGKDVESCHDMAALNILKLLSE 555

Query: 481 LDQQSTEMPRTGNGPMSVCGRC 502
           LDQQSTEMPRTGNGPMSVCGRC
Sbjct: 556 LDQQSTEMPRTGNGPMSVCGRC 577


>gi|82659085 staufen isoform a [Homo sapiens]
          Length = 496

 Score =  992 bits (2565), Expect = 0.0
 Identities = 496/502 (98%), Positives = 496/502 (98%), Gaps = 6/502 (1%)

Query: 1   MKLGKKPMYKPVDPYSRMQSTYNYNMRGGAYPPRYFYPFPVPPLLYQVELSVGGQQFNGK 60
           MKLGKKPMYKPVDPYSRMQSTYNYNMRGGAYPPRYFYPFPVPPLLYQVELSVGGQQFNGK
Sbjct: 1   MKLGKKPMYKPVDPYSRMQSTYNYNMRGGAYPPRYFYPFPVPPLLYQVELSVGGQQFNGK 60

Query: 61  GKTRQAAKHDAAAKALRILQNEPLPERLEVNGRESEEENLNKSEISQVFEIALKRNLPVN 120
           GKTRQAAKHDAAAKALRILQNEPLPERLEVNGRESEEENLNKSEISQVFEIALKRNLPVN
Sbjct: 61  GKTRQAAKHDAAAKALRILQNEPLPERLEVNGRESEEENLNKSEISQVFEIALKRNLPVN 120

Query: 121 FESFPLKQVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLPPL 180
           FE      VARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLPPL
Sbjct: 121 FE------VARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLPPL 174

Query: 181 PAVERVKPRIKKKTKPIVKPQTSPEYGQGINPISRLAQIQQAKKEKEPEYTLLTERGLPR 240
           PAVERVKPRIKKKTKPIVKPQTSPEYGQGINPISRLAQIQQAKKEKEPEYTLLTERGLPR
Sbjct: 175 PAVERVKPRIKKKTKPIVKPQTSPEYGQGINPISRLAQIQQAKKEKEPEYTLLTERGLPR 234

Query: 241 RREFVMQVKVGNHTAEGTGTNKKVAKRNAAENMLEILGFKVPQAQPTKPALKSEEKTPIK 300
           RREFVMQVKVGNHTAEGTGTNKKVAKRNAAENMLEILGFKVPQAQPTKPALKSEEKTPIK
Sbjct: 235 RREFVMQVKVGNHTAEGTGTNKKVAKRNAAENMLEILGFKVPQAQPTKPALKSEEKTPIK 294

Query: 301 KPGDGRKVTFFEPGSGDENGTSNKEDEFRMPYLSHQQLPAGILPMVPEVAQAVGVSQGHH 360
           KPGDGRKVTFFEPGSGDENGTSNKEDEFRMPYLSHQQLPAGILPMVPEVAQAVGVSQGHH
Sbjct: 295 KPGDGRKVTFFEPGSGDENGTSNKEDEFRMPYLSHQQLPAGILPMVPEVAQAVGVSQGHH 354

Query: 361 TKDFTRAAPNPAKATVTAMIARELLYGGTSPTAETILKNNISSGHVPHGPLTRPSEQLDY 420
           TKDFTRAAPNPAKATVTAMIARELLYGGTSPTAETILKNNISSGHVPHGPLTRPSEQLDY
Sbjct: 355 TKDFTRAAPNPAKATVTAMIARELLYGGTSPTAETILKNNISSGHVPHGPLTRPSEQLDY 414

Query: 421 LSRVQGFQVEYKDFPKNNKNEFVSLINCSSQPPLISHGIGKDVESCHDMAALNILKLLSE 480
           LSRVQGFQVEYKDFPKNNKNEFVSLINCSSQPPLISHGIGKDVESCHDMAALNILKLLSE
Sbjct: 415 LSRVQGFQVEYKDFPKNNKNEFVSLINCSSQPPLISHGIGKDVESCHDMAALNILKLLSE 474

Query: 481 LDQQSTEMPRTGNGPMSVCGRC 502
           LDQQSTEMPRTGNGPMSVCGRC
Sbjct: 475 LDQQSTEMPRTGNGPMSVCGRC 496


>gi|82659083 staufen isoform a [Homo sapiens]
          Length = 496

 Score =  992 bits (2565), Expect = 0.0
 Identities = 496/502 (98%), Positives = 496/502 (98%), Gaps = 6/502 (1%)

Query: 1   MKLGKKPMYKPVDPYSRMQSTYNYNMRGGAYPPRYFYPFPVPPLLYQVELSVGGQQFNGK 60
           MKLGKKPMYKPVDPYSRMQSTYNYNMRGGAYPPRYFYPFPVPPLLYQVELSVGGQQFNGK
Sbjct: 1   MKLGKKPMYKPVDPYSRMQSTYNYNMRGGAYPPRYFYPFPVPPLLYQVELSVGGQQFNGK 60

Query: 61  GKTRQAAKHDAAAKALRILQNEPLPERLEVNGRESEEENLNKSEISQVFEIALKRNLPVN 120
           GKTRQAAKHDAAAKALRILQNEPLPERLEVNGRESEEENLNKSEISQVFEIALKRNLPVN
Sbjct: 61  GKTRQAAKHDAAAKALRILQNEPLPERLEVNGRESEEENLNKSEISQVFEIALKRNLPVN 120

Query: 121 FESFPLKQVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLPPL 180
           FE      VARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLPPL
Sbjct: 121 FE------VARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLPPL 174

Query: 181 PAVERVKPRIKKKTKPIVKPQTSPEYGQGINPISRLAQIQQAKKEKEPEYTLLTERGLPR 240
           PAVERVKPRIKKKTKPIVKPQTSPEYGQGINPISRLAQIQQAKKEKEPEYTLLTERGLPR
Sbjct: 175 PAVERVKPRIKKKTKPIVKPQTSPEYGQGINPISRLAQIQQAKKEKEPEYTLLTERGLPR 234

Query: 241 RREFVMQVKVGNHTAEGTGTNKKVAKRNAAENMLEILGFKVPQAQPTKPALKSEEKTPIK 300
           RREFVMQVKVGNHTAEGTGTNKKVAKRNAAENMLEILGFKVPQAQPTKPALKSEEKTPIK
Sbjct: 235 RREFVMQVKVGNHTAEGTGTNKKVAKRNAAENMLEILGFKVPQAQPTKPALKSEEKTPIK 294

Query: 301 KPGDGRKVTFFEPGSGDENGTSNKEDEFRMPYLSHQQLPAGILPMVPEVAQAVGVSQGHH 360
           KPGDGRKVTFFEPGSGDENGTSNKEDEFRMPYLSHQQLPAGILPMVPEVAQAVGVSQGHH
Sbjct: 295 KPGDGRKVTFFEPGSGDENGTSNKEDEFRMPYLSHQQLPAGILPMVPEVAQAVGVSQGHH 354

Query: 361 TKDFTRAAPNPAKATVTAMIARELLYGGTSPTAETILKNNISSGHVPHGPLTRPSEQLDY 420
           TKDFTRAAPNPAKATVTAMIARELLYGGTSPTAETILKNNISSGHVPHGPLTRPSEQLDY
Sbjct: 355 TKDFTRAAPNPAKATVTAMIARELLYGGTSPTAETILKNNISSGHVPHGPLTRPSEQLDY 414

Query: 421 LSRVQGFQVEYKDFPKNNKNEFVSLINCSSQPPLISHGIGKDVESCHDMAALNILKLLSE 480
           LSRVQGFQVEYKDFPKNNKNEFVSLINCSSQPPLISHGIGKDVESCHDMAALNILKLLSE
Sbjct: 415 LSRVQGFQVEYKDFPKNNKNEFVSLINCSSQPPLISHGIGKDVESCHDMAALNILKLLSE 474

Query: 481 LDQQSTEMPRTGNGPMSVCGRC 502
           LDQQSTEMPRTGNGPMSVCGRC
Sbjct: 475 LDQQSTEMPRTGNGPMSVCGRC 496


>gi|7657625 staufen homolog 2 [Homo sapiens]
          Length = 479

 Score =  364 bits (934), Expect = e-100
 Identities = 231/448 (51%), Positives = 283/448 (63%), Gaps = 60/448 (13%)

Query: 1   MKLGKKPMYKPVDPYSRMQSTYNYNMRGGAYPPRYFYPFPVPPLLYQVELSVGGQQFNGK 60
           MK G+  +Y+P+DP        NYN RG  Y  RY  P P    ++ V+L+VG  +F G+
Sbjct: 73  MKRGEPAIYRPLDPKPFPNYRANYNFRG-MYNQRYHCPVPK---IFYVQLTVGNNEFFGE 128

Query: 61  GKTRQAAKHDAAAKALRILQNEPLPERLEVNGRES----EEENLNKSEISQVFEIALKRN 116
           GKTRQAA+H+AA KAL+ LQNEP+PER   NG       ++++ NKSEIS VFEIALKRN
Sbjct: 129 GKTRQAARHNAAMKALQALQNEPIPERSPQNGESGKDMDDDKDANKSEISLVFEIALKRN 188

Query: 117 LPVNFESFPLKQVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKK 176
           +PV+FE      V +ESGPPHMK+FVT+VSVGEF  EGEG SKK+SKK AA  VL+ELKK
Sbjct: 189 MPVSFE------VIKESGPPHMKSFVTRVSVGEFSAEGEGNSKKLSKKRAATTVLQELKK 242

Query: 177 LPPLPAVERVKPRIKKKTKPIVKPQTSPEYGQGINPISRLAQIQQAKKEKEPEYTLLTER 236
           LPPLP VE+ K   KK+ K IVK    PEYGQG+NPISRLAQIQQAKKEKEP+Y LL+ER
Sbjct: 243 LPPLPVVEKPKLFFKKRPKTIVK--AGPEYGQGMNPISRLAQIQQAKKEKEPDYVLLSER 300

Query: 237 GLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNAAENMLEILGFKVPQAQPTKPALKSEEK 296
           G+PRRREFVMQVKVGN  A GTG NKK+AK+NAAE ML  LG+K      +       EK
Sbjct: 301 GMPRRREFVMQVKVGNEVATGTGPNKKIAKKNAAEAMLLQLGYKA-----STNLQDQLEK 355

Query: 297 TPIKKPGDGRKVTFFEPGSGDENGTSNKEDEFRMPYLSHQQLPAGILPMVPEVAQAV--- 353
           T   K   G K  F EP       T+N               P GIL + P+V Q +   
Sbjct: 356 TGENKGWSGPKPGFPEP-------TNN--------------TPKGILHLSPDVYQEMEAS 394

Query: 354 ------GVSQGH-HTKDFTRAAPN----PAKATVTAMIARELLYGGTSPTAETI-LKNNI 401
                 G + G+   KD  + + +       +  +A IARELL  GTS TAE I LK   
Sbjct: 395 RHKVISGTTLGYLSPKDMNQPSSSFFSISPTSNSSATIARELLMNGTSSTAEAIGLKG-- 452

Query: 402 SSGHVPHGPLTRPSEQLDYLSRVQGFQV 429
           SS   P  P+ +PS+QL+YL+R+QGFQV
Sbjct: 453 SSPTPPCSPV-QPSKQLEYLARIQGFQV 479



 Score = 69.3 bits (168), Expect = 8e-12
 Identities = 71/274 (25%), Positives = 120/274 (43%), Gaps = 33/274 (12%)

Query: 45  LYQVELSVGGQQFNGKGKTRQAAKHDAAAKALRILQNEPLPERLEVNGRESEEENLNKSE 104
           ++ V+LS+G Q +  +G + + A+   A KA   L    LP+   V        N N   
Sbjct: 7   MFSVQLSLGEQTWESEGSSIKKAQQAVANKA---LTESTLPK--PVQKPPKSNVNNNPGS 61

Query: 105 ISQVFE---IALKRNLPVNFESFPLKQVARESGP-------------PHMKNFVTKVSVG 148
           I+   E   +A+KR  P  +     K                     P  K F  +++VG
Sbjct: 62  ITPTVELNGLAMKRGEPAIYRPLDPKPFPNYRANYNFRGMYNQRYHCPVPKIFYVQLTVG 121

Query: 149 EFVGEGEGKSKKISKKNAAIAVLEELKKLPPLPAVERVKPRIKKKTKPIVKPQTSPEYGQ 208
                GEGK+++ ++ NAA+  L+ L+  P    +    P+  +  K +   + + +   
Sbjct: 122 NNEFFGEGKTRQAARHNAAMKALQALQNEP----IPERSPQNGESGKDMDDDKDANK--- 174

Query: 209 GINPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRN 268
             + IS + +I   K+     + ++ E G P  + FV +V VG  +AEG G +KK++K+ 
Sbjct: 175 --SEISLVFEI-ALKRNMPVSFEVIKESGPPHMKSFVTRVSVGEFSAEGEGNSKKLSKKR 231

Query: 269 AAENMLEILGFKVPQAQPTKPAL--KSEEKTPIK 300
           AA  +L+ L    P     KP L  K   KT +K
Sbjct: 232 AATTVLQELKKLPPLPVVEKPKLFFKKRPKTIVK 265


>gi|19743838 TAR RNA binding protein 2 isoform b [Homo sapiens]
          Length = 345

 Score = 77.0 bits (188), Expect = 4e-14
 Identities = 56/192 (29%), Positives = 86/192 (44%), Gaps = 29/192 (15%)

Query: 111 IALKRNLPVNFESFPLKQVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAV 170
           I+L +         P+  + +  G  H  NF  +V+VG+    G+G SKK +K  AA   
Sbjct: 11  ISLLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTVGDTSCTGQGPSKKAAKHKAAEVA 70

Query: 171 LEELK------------------------KLPPLPAVERVKPR---IKKKTKPI-VKPQT 202
           L+ LK                         +P   A     P    +  ++ P+ ++P  
Sbjct: 71  LKHLKGGSMLEPALEDSSSFSPLDSSLPEDIPVFTAAAAATPVPSVVLTRSPPMELQPPV 130

Query: 203 SPEYGQGINPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNK 262
           SP+  +  NP+  L ++   K  + PEYT+  E G   R+EF M  +V      G+GT+K
Sbjct: 131 SPQQSE-CNPVGALQELVVQKGWRLPEYTVTQESGPAHRKEFTMTCRVERFIEIGSGTSK 189

Query: 263 KVAKRNAAENML 274
           K+AKRNAA  ML
Sbjct: 190 KLAKRNAAAKML 201



 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 53/213 (24%), Positives = 88/213 (41%), Gaps = 49/213 (23%)

Query: 4   GKKPMYKPVDPYSRMQSTYNYNM---RGGAYPPRYFYPFPVPPLLYQVELSVGGQQFNGK 60
           GK P+    +  +R+  T  Y++    G A+ P + +            ++VG     G+
Sbjct: 7   GKTPISLLQEYGTRIGKTPVYDLLKAEGQAHQPNFTF-----------RVTVGDTSCTGQ 55

Query: 61  GKTRQAAKHDAAAKALRILQNEPLPE-RLEVNGRESEEENLNKSEI---------SQVFE 110
           G +++AAKH AA  AL+ L+   + E  LE +   S  ++    +I         + V  
Sbjct: 56  GPSKKAAKHKAAEVALKHLKGGSMLEPALEDSSSFSPLDSSLPEDIPVFTAAAAATPVPS 115

Query: 111 IALKRNLPVNFES-------------------------FPLKQVARESGPPHMKNFVTKV 145
           + L R+ P+  +                           P   V +ESGP H K F    
Sbjct: 116 VVLTRSPPMELQPPVSPQQSECNPVGALQELVVQKGWRLPEYTVTQESGPAHRKEFTMTC 175

Query: 146 SVGEFVGEGEGKSKKISKKNAAIAVLEELKKLP 178
            V  F+  G G SKK++K+NAA  +L  +  +P
Sbjct: 176 RVERFIEIGSGTSKKLAKRNAAAKMLLRVHTVP 208



 Score = 40.0 bits (92), Expect = 0.005
 Identities = 27/69 (39%), Positives = 34/69 (49%), Gaps = 1/69 (1%)

Query: 209 GINPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRN 268
           G  PIS L Q    +  K P Y LL   G   +  F  +V VG+ +  G G +KK AK  
Sbjct: 7   GKTPIS-LLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTVGDTSCTGQGPSKKAAKHK 65

Query: 269 AAENMLEIL 277
           AAE  L+ L
Sbjct: 66  AAEVALKHL 74


>gi|19743840 TAR RNA binding protein 2 isoform a [Homo sapiens]
          Length = 366

 Score = 77.0 bits (188), Expect = 4e-14
 Identities = 56/192 (29%), Positives = 86/192 (44%), Gaps = 29/192 (15%)

Query: 111 IALKRNLPVNFESFPLKQVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAV 170
           I+L +         P+  + +  G  H  NF  +V+VG+    G+G SKK +K  AA   
Sbjct: 32  ISLLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTVGDTSCTGQGPSKKAAKHKAAEVA 91

Query: 171 LEELK------------------------KLPPLPAVERVKPR---IKKKTKPI-VKPQT 202
           L+ LK                         +P   A     P    +  ++ P+ ++P  
Sbjct: 92  LKHLKGGSMLEPALEDSSSFSPLDSSLPEDIPVFTAAAAATPVPSVVLTRSPPMELQPPV 151

Query: 203 SPEYGQGINPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNK 262
           SP+  +  NP+  L ++   K  + PEYT+  E G   R+EF M  +V      G+GT+K
Sbjct: 152 SPQQSE-CNPVGALQELVVQKGWRLPEYTVTQESGPAHRKEFTMTCRVERFIEIGSGTSK 210

Query: 263 KVAKRNAAENML 274
           K+AKRNAA  ML
Sbjct: 211 KLAKRNAAAKML 222



 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 53/213 (24%), Positives = 88/213 (41%), Gaps = 49/213 (23%)

Query: 4   GKKPMYKPVDPYSRMQSTYNYNM---RGGAYPPRYFYPFPVPPLLYQVELSVGGQQFNGK 60
           GK P+    +  +R+  T  Y++    G A+ P + +            ++VG     G+
Sbjct: 28  GKTPISLLQEYGTRIGKTPVYDLLKAEGQAHQPNFTF-----------RVTVGDTSCTGQ 76

Query: 61  GKTRQAAKHDAAAKALRILQNEPLPE-RLEVNGRESEEENLNKSEI---------SQVFE 110
           G +++AAKH AA  AL+ L+   + E  LE +   S  ++    +I         + V  
Sbjct: 77  GPSKKAAKHKAAEVALKHLKGGSMLEPALEDSSSFSPLDSSLPEDIPVFTAAAAATPVPS 136

Query: 111 IALKRNLPVNFES-------------------------FPLKQVARESGPPHMKNFVTKV 145
           + L R+ P+  +                           P   V +ESGP H K F    
Sbjct: 137 VVLTRSPPMELQPPVSPQQSECNPVGALQELVVQKGWRLPEYTVTQESGPAHRKEFTMTC 196

Query: 146 SVGEFVGEGEGKSKKISKKNAAIAVLEELKKLP 178
            V  F+  G G SKK++K+NAA  +L  +  +P
Sbjct: 197 RVERFIEIGSGTSKKLAKRNAAAKMLLRVHTVP 229



 Score = 40.0 bits (92), Expect = 0.005
 Identities = 27/69 (39%), Positives = 34/69 (49%), Gaps = 1/69 (1%)

Query: 209 GINPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRN 268
           G  PIS L Q    +  K P Y LL   G   +  F  +V VG+ +  G G +KK AK  
Sbjct: 28  GKTPIS-LLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTVGDTSCTGQGPSKKAAKHK 86

Query: 269 AAENMLEIL 277
           AAE  L+ L
Sbjct: 87  AAEVALKHL 95


>gi|85068512 TAR RNA binding protein 2 isoform b [Homo sapiens]
          Length = 345

 Score = 77.0 bits (188), Expect = 4e-14
 Identities = 56/192 (29%), Positives = 86/192 (44%), Gaps = 29/192 (15%)

Query: 111 IALKRNLPVNFESFPLKQVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAV 170
           I+L +         P+  + +  G  H  NF  +V+VG+    G+G SKK +K  AA   
Sbjct: 11  ISLLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTVGDTSCTGQGPSKKAAKHKAAEVA 70

Query: 171 LEELK------------------------KLPPLPAVERVKPR---IKKKTKPI-VKPQT 202
           L+ LK                         +P   A     P    +  ++ P+ ++P  
Sbjct: 71  LKHLKGGSMLEPALEDSSSFSPLDSSLPEDIPVFTAAAAATPVPSVVLTRSPPMELQPPV 130

Query: 203 SPEYGQGINPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNK 262
           SP+  +  NP+  L ++   K  + PEYT+  E G   R+EF M  +V      G+GT+K
Sbjct: 131 SPQQSE-CNPVGALQELVVQKGWRLPEYTVTQESGPAHRKEFTMTCRVERFIEIGSGTSK 189

Query: 263 KVAKRNAAENML 274
           K+AKRNAA  ML
Sbjct: 190 KLAKRNAAAKML 201



 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 53/213 (24%), Positives = 88/213 (41%), Gaps = 49/213 (23%)

Query: 4   GKKPMYKPVDPYSRMQSTYNYNM---RGGAYPPRYFYPFPVPPLLYQVELSVGGQQFNGK 60
           GK P+    +  +R+  T  Y++    G A+ P + +            ++VG     G+
Sbjct: 7   GKTPISLLQEYGTRIGKTPVYDLLKAEGQAHQPNFTF-----------RVTVGDTSCTGQ 55

Query: 61  GKTRQAAKHDAAAKALRILQNEPLPE-RLEVNGRESEEENLNKSEI---------SQVFE 110
           G +++AAKH AA  AL+ L+   + E  LE +   S  ++    +I         + V  
Sbjct: 56  GPSKKAAKHKAAEVALKHLKGGSMLEPALEDSSSFSPLDSSLPEDIPVFTAAAAATPVPS 115

Query: 111 IALKRNLPVNFES-------------------------FPLKQVARESGPPHMKNFVTKV 145
           + L R+ P+  +                           P   V +ESGP H K F    
Sbjct: 116 VVLTRSPPMELQPPVSPQQSECNPVGALQELVVQKGWRLPEYTVTQESGPAHRKEFTMTC 175

Query: 146 SVGEFVGEGEGKSKKISKKNAAIAVLEELKKLP 178
            V  F+  G G SKK++K+NAA  +L  +  +P
Sbjct: 176 RVERFIEIGSGTSKKLAKRNAAAKMLLRVHTVP 208



 Score = 40.0 bits (92), Expect = 0.005
 Identities = 27/69 (39%), Positives = 34/69 (49%), Gaps = 1/69 (1%)

Query: 209 GINPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRN 268
           G  PIS L Q    +  K P Y LL   G   +  F  +V VG+ +  G G +KK AK  
Sbjct: 7   GKTPIS-LLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTVGDTSCTGQGPSKKAAKHK 65

Query: 269 AAENMLEIL 277
           AAE  L+ L
Sbjct: 66  AAEVALKHL 74


>gi|213417919 protein kinase, interferon-inducible double stranded
           RNA dependent activator isoform 3 [Homo sapiens]
          Length = 288

 Score = 68.9 bits (167), Expect = 1e-11
 Identities = 47/153 (30%), Positives = 70/153 (45%), Gaps = 10/153 (6%)

Query: 122 ESFPLKQVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLPPLP 181
           ++ P+ +  R     H+  F  +V+VG+    GEG SKK++K  AA A +  LK      
Sbjct: 22  KNIPVYECERSDVQIHVPTFTFRVTVGDITCTGEGTSKKLAKHRAAEAAINILK------ 75

Query: 182 AVERVKPRIKKKTKPIVKPQTSPEYGQGINPISRLAQIQQAKKEKEPEYTLLTERGLPRR 241
                   I       + P  S +    +NPI  L ++      + PEYTL  E G   +
Sbjct: 76  ----ANASICFAVPDPLMPDPSKQPKNQLNPIGSLQELAIHHGWRLPEYTLSQEGGPAHK 131

Query: 242 REFVMQVKVGNHTAEGTGTNKKVAKRNAAENML 274
           RE+    ++ +    G G +KK AKRNAAE  L
Sbjct: 132 REYTTICRLESFMETGKGASKKQAKRNAAEKFL 164



 Score = 53.1 bits (126), Expect = 6e-07
 Identities = 40/144 (27%), Positives = 70/144 (48%), Gaps = 14/144 (9%)

Query: 41  VPPLLYQVELSVGGQQFNGKGKTRQAAKHDAAAKALRILQNEP-----LPERLEVNGRES 95
           VP   ++V  +VG     G+G +++ AKH AA  A+ IL+        +P+ L  +  + 
Sbjct: 38  VPTFTFRV--TVGDITCTGEGTSKKLAKHRAAEAAINILKANASICFAVPDPLMPDPSKQ 95

Query: 96  EEENLNKSEISQVFEIALKRNLPVNFESFPLKQVARESGPPHMKNFVTKVSVGEFVGEGE 155
            +  LN   I  + E+A+     +     P   +++E GP H + + T   +  F+  G+
Sbjct: 96  PKNQLNP--IGSLQELAIHHGWRL-----PEYTLSQEGGPAHKREYTTICRLESFMETGK 148

Query: 156 GKSKKISKKNAAIAVLEELKKLPP 179
           G SKK +K+NAA   L +   + P
Sbjct: 149 GASKKQAKRNAAEKFLAKFSNISP 172



 Score = 42.7 bits (99), Expect = 8e-04
 Identities = 60/249 (24%), Positives = 97/249 (38%), Gaps = 22/249 (8%)

Query: 244 FVMQVKVGNHTAEGTGTNKKVAKRNAAENMLEILG------FKVPQAQPTKPALKSEEKT 297
           F  +V VG+ T  G GT+KK+AK  AAE  + IL       F VP   P  P    + K 
Sbjct: 41  FTFRVTVGDITCTGEGTSKKLAKHRAAEAAINILKANASICFAVP--DPLMPDPSKQPKN 98

Query: 298 PIKKPGDGRKVTFF------EPGSGDENGTSNKEDEFRMPYL-SHQQLPAGILPMVPEVA 350
            +   G  +++         E     E G ++K +   +  L S  +   G         
Sbjct: 99  QLNPIGSLQELAIHHGWRLPEYTLSQEGGPAHKREYTTICRLESFMETGKG-----ASKK 153

Query: 351 QAVGVSQGHHTKDFTRAAPNPAKATVTAMIARELLYGGTSPTAETILKNNISSGHVPHGP 410
           QA   +       F+  +P     ++T ++   L     S       K N+    +   P
Sbjct: 154 QAKRNAAEKFLAKFSNISPE-NHISLTNVVGHSLGCTWHSLRNSPGEKINLLKRSLLSIP 212

Query: 411 LTRPSEQLDYLSRVQGFQVEYKDFPKNNKN-EFVSLINCSSQPPLISHGIGKDVESCHDM 469
            T   + L  +++ QGF + Y D  + + N ++  L   S+ P  + HG G    +    
Sbjct: 213 NTDYIQLLSEIAKEQGFNITYLDIDELSANGQYQCLAELSTSPITVCHGSGISCGNAQSD 272

Query: 470 AALNILKLL 478
           AA N L+ L
Sbjct: 273 AAHNALQYL 281


>gi|213417911 protein kinase, interferon-inducible double stranded
           RNA dependent activator isoform 2 [Homo sapiens]
          Length = 302

 Score = 68.9 bits (167), Expect = 1e-11
 Identities = 47/153 (30%), Positives = 70/153 (45%), Gaps = 10/153 (6%)

Query: 122 ESFPLKQVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLPPLP 181
           ++ P+ +  R     H+  F  +V+VG+    GEG SKK++K  AA A +  LK      
Sbjct: 36  KNIPVYECERSDVQIHVPTFTFRVTVGDITCTGEGTSKKLAKHRAAEAAINILK------ 89

Query: 182 AVERVKPRIKKKTKPIVKPQTSPEYGQGINPISRLAQIQQAKKEKEPEYTLLTERGLPRR 241
                   I       + P  S +    +NPI  L ++      + PEYTL  E G   +
Sbjct: 90  ----ANASICFAVPDPLMPDPSKQPKNQLNPIGSLQELAIHHGWRLPEYTLSQEGGPAHK 145

Query: 242 REFVMQVKVGNHTAEGTGTNKKVAKRNAAENML 274
           RE+    ++ +    G G +KK AKRNAAE  L
Sbjct: 146 REYTTICRLESFMETGKGASKKQAKRNAAEKFL 178



 Score = 53.5 bits (127), Expect = 4e-07
 Identities = 50/186 (26%), Positives = 84/186 (45%), Gaps = 20/186 (10%)

Query: 3   LGKKPMYKPVDPYSRMQSTYNYNMRGGAYP----PRYFYPFPVPPLLYQVELSVGGQQFN 58
           LGK    KP    + +Q  + Y M+    P     R      VP   ++V  +VG     
Sbjct: 12  LGKMITAKPGK--TPIQVLHEYGMKTKNIPVYECERSDVQIHVPTFTFRV--TVGDITCT 67

Query: 59  GKGKTRQAAKHDAAAKALRILQNEP-----LPERLEVNGRESEEENLNKSEISQVFEIAL 113
           G+G +++ AKH AA  A+ IL+        +P+ L  +  +  +  LN   I  + E+A+
Sbjct: 68  GEGTSKKLAKHRAAEAAINILKANASICFAVPDPLMPDPSKQPKNQLNP--IGSLQELAI 125

Query: 114 KRNLPVNFESFPLKQVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEE 173
                +     P   +++E GP H + + T   +  F+  G+G SKK +K+NAA   L +
Sbjct: 126 HHGWRL-----PEYTLSQEGGPAHKREYTTICRLESFMETGKGASKKQAKRNAAEKFLAK 180

Query: 174 LKKLPP 179
              + P
Sbjct: 181 FSNISP 186



 Score = 42.7 bits (99), Expect = 8e-04
 Identities = 60/249 (24%), Positives = 97/249 (38%), Gaps = 22/249 (8%)

Query: 244 FVMQVKVGNHTAEGTGTNKKVAKRNAAENMLEILG------FKVPQAQPTKPALKSEEKT 297
           F  +V VG+ T  G GT+KK+AK  AAE  + IL       F VP   P  P    + K 
Sbjct: 55  FTFRVTVGDITCTGEGTSKKLAKHRAAEAAINILKANASICFAVP--DPLMPDPSKQPKN 112

Query: 298 PIKKPGDGRKVTFF------EPGSGDENGTSNKEDEFRMPYL-SHQQLPAGILPMVPEVA 350
            +   G  +++         E     E G ++K +   +  L S  +   G         
Sbjct: 113 QLNPIGSLQELAIHHGWRLPEYTLSQEGGPAHKREYTTICRLESFMETGKG-----ASKK 167

Query: 351 QAVGVSQGHHTKDFTRAAPNPAKATVTAMIARELLYGGTSPTAETILKNNISSGHVPHGP 410
           QA   +       F+  +P     ++T ++   L     S       K N+    +   P
Sbjct: 168 QAKRNAAEKFLAKFSNISPE-NHISLTNVVGHSLGCTWHSLRNSPGEKINLLKRSLLSIP 226

Query: 411 LTRPSEQLDYLSRVQGFQVEYKDFPKNNKN-EFVSLINCSSQPPLISHGIGKDVESCHDM 469
            T   + L  +++ QGF + Y D  + + N ++  L   S+ P  + HG G    +    
Sbjct: 227 NTDYIQLLSEIAKEQGFNITYLDIDELSANGQYQCLAELSTSPITVCHGSGISCGNAQSD 286

Query: 470 AALNILKLL 478
           AA N L+ L
Sbjct: 287 AAHNALQYL 295


>gi|4505581 protein kinase, interferon-inducible double stranded RNA
           dependent activator isoform 1 [Homo sapiens]
          Length = 313

 Score = 68.9 bits (167), Expect = 1e-11
 Identities = 47/153 (30%), Positives = 70/153 (45%), Gaps = 10/153 (6%)

Query: 122 ESFPLKQVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLPPLP 181
           ++ P+ +  R     H+  F  +V+VG+    GEG SKK++K  AA A +  LK      
Sbjct: 47  KNIPVYECERSDVQIHVPTFTFRVTVGDITCTGEGTSKKLAKHRAAEAAINILK------ 100

Query: 182 AVERVKPRIKKKTKPIVKPQTSPEYGQGINPISRLAQIQQAKKEKEPEYTLLTERGLPRR 241
                   I       + P  S +    +NPI  L ++      + PEYTL  E G   +
Sbjct: 101 ----ANASICFAVPDPLMPDPSKQPKNQLNPIGSLQELAIHHGWRLPEYTLSQEGGPAHK 156

Query: 242 REFVMQVKVGNHTAEGTGTNKKVAKRNAAENML 274
           RE+    ++ +    G G +KK AKRNAAE  L
Sbjct: 157 REYTTICRLESFMETGKGASKKQAKRNAAEKFL 189



 Score = 53.5 bits (127), Expect = 4e-07
 Identities = 50/186 (26%), Positives = 84/186 (45%), Gaps = 20/186 (10%)

Query: 3   LGKKPMYKPVDPYSRMQSTYNYNMRGGAYP----PRYFYPFPVPPLLYQVELSVGGQQFN 58
           LGK    KP    + +Q  + Y M+    P     R      VP   ++V  +VG     
Sbjct: 23  LGKMITAKPGK--TPIQVLHEYGMKTKNIPVYECERSDVQIHVPTFTFRV--TVGDITCT 78

Query: 59  GKGKTRQAAKHDAAAKALRILQNEP-----LPERLEVNGRESEEENLNKSEISQVFEIAL 113
           G+G +++ AKH AA  A+ IL+        +P+ L  +  +  +  LN   I  + E+A+
Sbjct: 79  GEGTSKKLAKHRAAEAAINILKANASICFAVPDPLMPDPSKQPKNQLNP--IGSLQELAI 136

Query: 114 KRNLPVNFESFPLKQVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEE 173
                +     P   +++E GP H + + T   +  F+  G+G SKK +K+NAA   L +
Sbjct: 137 HHGWRL-----PEYTLSQEGGPAHKREYTTICRLESFMETGKGASKKQAKRNAAEKFLAK 191

Query: 174 LKKLPP 179
              + P
Sbjct: 192 FSNISP 197



 Score = 42.7 bits (99), Expect = 8e-04
 Identities = 60/249 (24%), Positives = 97/249 (38%), Gaps = 22/249 (8%)

Query: 244 FVMQVKVGNHTAEGTGTNKKVAKRNAAENMLEILG------FKVPQAQPTKPALKSEEKT 297
           F  +V VG+ T  G GT+KK+AK  AAE  + IL       F VP   P  P    + K 
Sbjct: 66  FTFRVTVGDITCTGEGTSKKLAKHRAAEAAINILKANASICFAVP--DPLMPDPSKQPKN 123

Query: 298 PIKKPGDGRKVTFF------EPGSGDENGTSNKEDEFRMPYL-SHQQLPAGILPMVPEVA 350
            +   G  +++         E     E G ++K +   +  L S  +   G         
Sbjct: 124 QLNPIGSLQELAIHHGWRLPEYTLSQEGGPAHKREYTTICRLESFMETGKG-----ASKK 178

Query: 351 QAVGVSQGHHTKDFTRAAPNPAKATVTAMIARELLYGGTSPTAETILKNNISSGHVPHGP 410
           QA   +       F+  +P     ++T ++   L     S       K N+    +   P
Sbjct: 179 QAKRNAAEKFLAKFSNISPE-NHISLTNVVGHSLGCTWHSLRNSPGEKINLLKRSLLSIP 237

Query: 411 LTRPSEQLDYLSRVQGFQVEYKDFPKNNKN-EFVSLINCSSQPPLISHGIGKDVESCHDM 469
            T   + L  +++ QGF + Y D  + + N ++  L   S+ P  + HG G    +    
Sbjct: 238 NTDYIQLLSEIAKEQGFNITYLDIDELSANGQYQCLAELSTSPITVCHGSGISCGNAQSD 297

Query: 470 AALNILKLL 478
           AA N L+ L
Sbjct: 298 AAHNALQYL 306


>gi|24234756 interleukin enhancer binding factor 3 isoform c [Homo
           sapiens]
          Length = 690

 Score = 57.4 bits (137), Expect = 3e-08
 Identities = 51/182 (28%), Positives = 78/182 (42%), Gaps = 30/182 (16%)

Query: 128 QVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEEL------------- 174
           ++  ++GP H   F   V V     E  G SKK +K + A+ VL+++             
Sbjct: 419 KLVSQTGPVHAPIFTMSVEVDGNSFEASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSK 478

Query: 175 -----KKLPPLPAVERVKPRIKKKTKPIVK--PQTSPEYG-----QGINPISRLAQIQQA 222
                ++    PAV    P ++  + P        + E G      G NP+  L +    
Sbjct: 479 GEDSAEETEAKPAVVAPAPVVEAVSTPSAAFPSDATAEQGPILTKHGKNPVMELNE---- 534

Query: 223 KKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNAAENMLEILGFKVP 282
            K +  +Y L++E G    + FVM+V+V     +G G+NKKVAK  AA   LE L    P
Sbjct: 535 -KRRGLKYELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAALEKLFPDTP 593

Query: 283 QA 284
            A
Sbjct: 594 LA 595



 Score = 46.6 bits (109), Expect = 5e-05
 Identities = 53/205 (25%), Positives = 82/205 (40%), Gaps = 39/205 (19%)

Query: 40  PVPPLLYQVELSVGGQQFNGKGKTRQAAKHDAAAKALRILQNEPLPERLE----VNGRES 95
           PV   ++ + + V G  F   G +++ AK   A K   +LQ+  LP   E      G +S
Sbjct: 426 PVHAPIFTMSVEVDGNSFEASGPSKKTAKLHVAVK---VLQDMGLPTGAEGRDSSKGEDS 482

Query: 96  EEENLNKSEISQVFEIALKRNLP--------------------------VNFESFPLK-Q 128
            EE   K  +     +    + P                          +N +   LK +
Sbjct: 483 AEETEAKPAVVAPAPVVEAVSTPSAAFPSDATAEQGPILTKHGKNPVMELNEKRRGLKYE 542

Query: 129 VARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLPPLPAVERVKP 188
           +  E+G  H K FV +V V     +G G +KK++K  AA+A LE+L    PL      K 
Sbjct: 543 LISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAALEKLFPDTPLALDANKKK 602

Query: 189 R----IKKKTKPIVKPQTSPEYGQG 209
           R    ++   K   KP  +P +G G
Sbjct: 603 RAPVPVRGGPKFAAKPH-NPGFGMG 626



 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 30/104 (28%), Positives = 52/104 (50%), Gaps = 7/104 (6%)

Query: 192 KKTKPIVKPQTSPEYGQGINPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVG 251
           KK K I K +   E  Q +N + RL Q++        +Y L+++ G      F M V+V 
Sbjct: 385 KKKKKIQKKEEKAEPPQAMNALMRLNQLKPGL-----QYKLVSQTGPVHAPIFTMSVEVD 439

Query: 252 NHTAEGTGTNKKVAKRNAAENMLEILGFKVPQAQPTKPALKSEE 295
            ++ E +G +KK AK + A  +L+ +G  +P     + + K E+
Sbjct: 440 GNSFEASGPSKKTAKLHVAVKVLQDMG--LPTGAEGRDSSKGED 481


>gi|24234753 interleukin enhancer binding factor 3 isoform b [Homo
           sapiens]
          Length = 702

 Score = 57.4 bits (137), Expect = 3e-08
 Identities = 51/182 (28%), Positives = 78/182 (42%), Gaps = 30/182 (16%)

Query: 128 QVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEEL------------- 174
           ++  ++GP H   F   V V     E  G SKK +K + A+ VL+++             
Sbjct: 419 KLVSQTGPVHAPIFTMSVEVDGNSFEASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSK 478

Query: 175 -----KKLPPLPAVERVKPRIKKKTKPIVK--PQTSPEYG-----QGINPISRLAQIQQA 222
                ++    PAV    P ++  + P        + E G      G NP+  L +    
Sbjct: 479 GEDSAEETEAKPAVVAPAPVVEAVSTPSAAFPSDATAEQGPILTKHGKNPVMELNE---- 534

Query: 223 KKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNAAENMLEILGFKVP 282
            K +  +Y L++E G    + FVM+V+V     +G G+NKKVAK  AA   LE L    P
Sbjct: 535 -KRRGLKYELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAALEKLFPDTP 593

Query: 283 QA 284
            A
Sbjct: 594 LA 595



 Score = 46.6 bits (109), Expect = 5e-05
 Identities = 53/205 (25%), Positives = 82/205 (40%), Gaps = 39/205 (19%)

Query: 40  PVPPLLYQVELSVGGQQFNGKGKTRQAAKHDAAAKALRILQNEPLPERLE----VNGRES 95
           PV   ++ + + V G  F   G +++ AK   A K   +LQ+  LP   E      G +S
Sbjct: 426 PVHAPIFTMSVEVDGNSFEASGPSKKTAKLHVAVK---VLQDMGLPTGAEGRDSSKGEDS 482

Query: 96  EEENLNKSEISQVFEIALKRNLP--------------------------VNFESFPLK-Q 128
            EE   K  +     +    + P                          +N +   LK +
Sbjct: 483 AEETEAKPAVVAPAPVVEAVSTPSAAFPSDATAEQGPILTKHGKNPVMELNEKRRGLKYE 542

Query: 129 VARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLPPLPAVERVKP 188
           +  E+G  H K FV +V V     +G G +KK++K  AA+A LE+L    PL      K 
Sbjct: 543 LISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAALEKLFPDTPLALDANKKK 602

Query: 189 R----IKKKTKPIVKPQTSPEYGQG 209
           R    ++   K   KP  +P +G G
Sbjct: 603 RAPVPVRGGPKFAAKPH-NPGFGMG 626



 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 30/104 (28%), Positives = 52/104 (50%), Gaps = 7/104 (6%)

Query: 192 KKTKPIVKPQTSPEYGQGINPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVG 251
           KK K I K +   E  Q +N + RL Q++        +Y L+++ G      F M V+V 
Sbjct: 385 KKKKKIQKKEEKAEPPQAMNALMRLNQLKPGL-----QYKLVSQTGPVHAPIFTMSVEVD 439

Query: 252 NHTAEGTGTNKKVAKRNAAENMLEILGFKVPQAQPTKPALKSEE 295
            ++ E +G +KK AK + A  +L+ +G  +P     + + K E+
Sbjct: 440 GNSFEASGPSKKTAKLHVAVKVLQDMG--LPTGAEGRDSSKGED 481


>gi|24234750 interleukin enhancer binding factor 3 isoform a [Homo
           sapiens]
          Length = 894

 Score = 57.4 bits (137), Expect = 3e-08
 Identities = 51/182 (28%), Positives = 78/182 (42%), Gaps = 30/182 (16%)

Query: 128 QVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEEL------------- 174
           ++  ++GP H   F   V V     E  G SKK +K + A+ VL+++             
Sbjct: 419 KLVSQTGPVHAPIFTMSVEVDGNSFEASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSK 478

Query: 175 -----KKLPPLPAVERVKPRIKKKTKPIVK--PQTSPEYG-----QGINPISRLAQIQQA 222
                ++    PAV    P ++  + P        + E G      G NP+  L +    
Sbjct: 479 GEDSAEETEAKPAVVAPAPVVEAVSTPSAAFPSDATAEQGPILTKHGKNPVMELNE---- 534

Query: 223 KKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNAAENMLEILGFKVP 282
            K +  +Y L++E G    + FVM+V+V     +G G+NKKVAK  AA   LE L    P
Sbjct: 535 -KRRGLKYELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAALEKLFPDTP 593

Query: 283 QA 284
            A
Sbjct: 594 LA 595



 Score = 46.6 bits (109), Expect = 5e-05
 Identities = 53/205 (25%), Positives = 82/205 (40%), Gaps = 39/205 (19%)

Query: 40  PVPPLLYQVELSVGGQQFNGKGKTRQAAKHDAAAKALRILQNEPLPERLE----VNGRES 95
           PV   ++ + + V G  F   G +++ AK   A K   +LQ+  LP   E      G +S
Sbjct: 426 PVHAPIFTMSVEVDGNSFEASGPSKKTAKLHVAVK---VLQDMGLPTGAEGRDSSKGEDS 482

Query: 96  EEENLNKSEISQVFEIALKRNLP--------------------------VNFESFPLK-Q 128
            EE   K  +     +    + P                          +N +   LK +
Sbjct: 483 AEETEAKPAVVAPAPVVEAVSTPSAAFPSDATAEQGPILTKHGKNPVMELNEKRRGLKYE 542

Query: 129 VARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLPPLPAVERVKP 188
           +  E+G  H K FV +V V     +G G +KK++K  AA+A LE+L    PL      K 
Sbjct: 543 LISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAALEKLFPDTPLALDANKKK 602

Query: 189 R----IKKKTKPIVKPQTSPEYGQG 209
           R    ++   K   KP  +P +G G
Sbjct: 603 RAPVPVRGGPKFAAKPH-NPGFGMG 626



 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 30/104 (28%), Positives = 52/104 (50%), Gaps = 7/104 (6%)

Query: 192 KKTKPIVKPQTSPEYGQGINPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVG 251
           KK K I K +   E  Q +N + RL Q++        +Y L+++ G      F M V+V 
Sbjct: 385 KKKKKIQKKEEKAEPPQAMNALMRLNQLKPGL-----QYKLVSQTGPVHAPIFTMSVEVD 439

Query: 252 NHTAEGTGTNKKVAKRNAAENMLEILGFKVPQAQPTKPALKSEE 295
            ++ E +G +KK AK + A  +L+ +G  +P     + + K E+
Sbjct: 440 GNSFEASGPSKKTAKLHVAVKVLQDMG--LPTGAEGRDSSKGED 481


>gi|212549555 interleukin enhancer binding factor 3 isoform e [Homo
           sapiens]
          Length = 706

 Score = 57.0 bits (136), Expect = 4e-08
 Identities = 52/186 (27%), Positives = 78/186 (41%), Gaps = 34/186 (18%)

Query: 128 QVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEEL------------- 174
           ++  ++GP H   F   V V     E  G SKK +K + A+ VL+++             
Sbjct: 419 KLVSQTGPVHAPIFTMSVEVDGNSFEASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSK 478

Query: 175 -----KKLPPLPAVERVKPRIKKKTKPI-----------VKPQTSPEYGQGINPISRLAQ 218
                ++    PAV    P ++  + P            VK Q       G NP+  L +
Sbjct: 479 GEDSAEETEAKPAVVAPAPVVEAVSTPSAAFPSDATAENVKQQGPILTKHGKNPVMELNE 538

Query: 219 IQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNAAENMLEILG 278
                K +  +Y L++E G    + FVM+V+V     +G G+NKKVAK  AA   LE L 
Sbjct: 539 -----KRRGLKYELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAALEKLF 593

Query: 279 FKVPQA 284
              P A
Sbjct: 594 PDTPLA 599



 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 55/209 (26%), Positives = 83/209 (39%), Gaps = 43/209 (20%)

Query: 40  PVPPLLYQVELSVGGQQFNGKGKTRQAAKHDAAAKALRILQNEPLPERLE----VNGRES 95
           PV   ++ + + V G  F   G +++ AK   A K   +LQ+  LP   E      G +S
Sbjct: 426 PVHAPIFTMSVEVDGNSFEASGPSKKTAKLHVAVK---VLQDMGLPTGAEGRDSSKGEDS 482

Query: 96  EEENLNK--------------------------SEISQVFEIALKRN----LPVNFESFP 125
            EE   K                            + Q   I  K      + +N +   
Sbjct: 483 AEETEAKPAVVAPAPVVEAVSTPSAAFPSDATAENVKQQGPILTKHGKNPVMELNEKRRG 542

Query: 126 LK-QVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLPPLPAVE 184
           LK ++  E+G  H K FV +V V     +G G +KK++K  AA+A LE+L    PL    
Sbjct: 543 LKYELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAALEKLFPDTPLALDA 602

Query: 185 RVKPR----IKKKTKPIVKPQTSPEYGQG 209
             K R    ++   K   KP  +P +G G
Sbjct: 603 NKKKRAPVPVRGGPKFAAKPH-NPGFGMG 630



 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 30/104 (28%), Positives = 52/104 (50%), Gaps = 7/104 (6%)

Query: 192 KKTKPIVKPQTSPEYGQGINPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVG 251
           KK K I K +   E  Q +N + RL Q++        +Y L+++ G      F M V+V 
Sbjct: 385 KKKKKIQKKEEKAEPPQAMNALMRLNQLKPGL-----QYKLVSQTGPVHAPIFTMSVEVD 439

Query: 252 NHTAEGTGTNKKVAKRNAAENMLEILGFKVPQAQPTKPALKSEE 295
            ++ E +G +KK AK + A  +L+ +G  +P     + + K E+
Sbjct: 440 GNSFEASGPSKKTAKLHVAVKVLQDMG--LPTGAEGRDSSKGED 481


>gi|212549553 interleukin enhancer binding factor 3 isoform d [Homo
           sapiens]
          Length = 898

 Score = 57.0 bits (136), Expect = 4e-08
 Identities = 52/186 (27%), Positives = 78/186 (41%), Gaps = 34/186 (18%)

Query: 128 QVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEEL------------- 174
           ++  ++GP H   F   V V     E  G SKK +K + A+ VL+++             
Sbjct: 419 KLVSQTGPVHAPIFTMSVEVDGNSFEASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSK 478

Query: 175 -----KKLPPLPAVERVKPRIKKKTKPI-----------VKPQTSPEYGQGINPISRLAQ 218
                ++    PAV    P ++  + P            VK Q       G NP+  L +
Sbjct: 479 GEDSAEETEAKPAVVAPAPVVEAVSTPSAAFPSDATAENVKQQGPILTKHGKNPVMELNE 538

Query: 219 IQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNAAENMLEILG 278
                K +  +Y L++E G    + FVM+V+V     +G G+NKKVAK  AA   LE L 
Sbjct: 539 -----KRRGLKYELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAALEKLF 593

Query: 279 FKVPQA 284
              P A
Sbjct: 594 PDTPLA 599



 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 55/209 (26%), Positives = 83/209 (39%), Gaps = 43/209 (20%)

Query: 40  PVPPLLYQVELSVGGQQFNGKGKTRQAAKHDAAAKALRILQNEPLPERLE----VNGRES 95
           PV   ++ + + V G  F   G +++ AK   A K   +LQ+  LP   E      G +S
Sbjct: 426 PVHAPIFTMSVEVDGNSFEASGPSKKTAKLHVAVK---VLQDMGLPTGAEGRDSSKGEDS 482

Query: 96  EEENLNK--------------------------SEISQVFEIALKRN----LPVNFESFP 125
            EE   K                            + Q   I  K      + +N +   
Sbjct: 483 AEETEAKPAVVAPAPVVEAVSTPSAAFPSDATAENVKQQGPILTKHGKNPVMELNEKRRG 542

Query: 126 LK-QVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLPPLPAVE 184
           LK ++  E+G  H K FV +V V     +G G +KK++K  AA+A LE+L    PL    
Sbjct: 543 LKYELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAALEKLFPDTPLALDA 602

Query: 185 RVKPR----IKKKTKPIVKPQTSPEYGQG 209
             K R    ++   K   KP  +P +G G
Sbjct: 603 NKKKRAPVPVRGGPKFAAKPH-NPGFGMG 630



 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 30/104 (28%), Positives = 52/104 (50%), Gaps = 7/104 (6%)

Query: 192 KKTKPIVKPQTSPEYGQGINPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVG 251
           KK K I K +   E  Q +N + RL Q++        +Y L+++ G      F M V+V 
Sbjct: 385 KKKKKIQKKEEKAEPPQAMNALMRLNQLKPGL-----QYKLVSQTGPVHAPIFTMSVEVD 439

Query: 252 NHTAEGTGTNKKVAKRNAAENMLEILGFKVPQAQPTKPALKSEE 295
            ++ E +G +KK AK + A  +L+ +G  +P     + + K E+
Sbjct: 440 GNSFEASGPSKKTAKLHVAVKVLQDMG--LPTGAEGRDSSKGED 481


>gi|237681091 RNA-specific adenosine deaminase B1 isoform 7 [Homo
           sapiens]
          Length = 674

 Score = 56.2 bits (134), Expect = 7e-08
 Identities = 73/258 (28%), Positives = 103/258 (39%), Gaps = 50/258 (19%)

Query: 40  PVPPLLYQVELSVGGQQFNGKGKTRQAAKHDAAAKALRILQNEPLPERLEVNGRESEEEN 99
           PV   L+ + + V GQ F G G T++ AK  AA KALR     P                
Sbjct: 103 PVHAPLFVMSVEVNGQVFEGSGPTKKKAKLHAAEKALRSFVQFP---------------- 146

Query: 100 LNKSEISQVFEIALKRNLPVNFESFPLKQVARESGPPHMKN-FVT--KVSVGEFVGEGEG 156
            N SE      +A+ R L VN + F   Q      P  + N F T  K     +VG    
Sbjct: 147 -NASEA----HLAMGRTLSVNTD-FTSDQA---DFPDTLFNGFETPDKAEPPFYVGSNGD 197

Query: 157 KSKKISKKNAAIAVLEELKKLPPLPAVERVKPRIKKKTKPIVKPQTSPEYGQGINPISRL 216
            S   S   +  A         P+PA       + +   P++ P   P    G NP+  L
Sbjct: 198 DSFSSSGDLSLSA--------SPVPA------SLAQPPLPVLPPFPPPS---GKNPVMIL 240

Query: 217 AQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNAAENMLEI 276
            +++   K     Y  L+E G    + FVM V V     EG+G NKK+AK  AA++ L  
Sbjct: 241 NELRPGLK-----YDFLSESGESHAKSFVMSVVVDGQFFEGSGRNKKLAKARAAQSALAA 295

Query: 277 LGFKVPQAQPTKPALKSE 294
           +        P++  + SE
Sbjct: 296 IFNLHLDQTPSRQPIPSE 313



 Score = 40.0 bits (92), Expect = 0.005
 Identities = 25/63 (39%), Positives = 34/63 (53%), Gaps = 2/63 (3%)

Query: 212 PISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNAAE 271
           P + L Q+ + K   +  YTLL++ G      FVM V+V     EG+G  KK AK +AAE
Sbjct: 79  PKNALMQLNEIKPGLQ--YTLLSQTGPVHAPLFVMSVEVNGQVFEGSGPTKKKAKLHAAE 136

Query: 272 NML 274
             L
Sbjct: 137 KAL 139



 Score = 32.7 bits (73), Expect = 0.79
 Identities = 18/47 (38%), Positives = 24/47 (51%)

Query: 132 ESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLP 178
           ++GP H   FV  V V   V EG G +KK +K +AA   L    + P
Sbjct: 100 QTGPVHAPLFVMSVEVNGQVFEGSGPTKKKAKLHAAEKALRSFVQFP 146


>gi|7669479 RNA-specific adenosine deaminase B1 isoform 3 [Homo
           sapiens]
          Length = 714

 Score = 56.2 bits (134), Expect = 7e-08
 Identities = 73/258 (28%), Positives = 103/258 (39%), Gaps = 50/258 (19%)

Query: 40  PVPPLLYQVELSVGGQQFNGKGKTRQAAKHDAAAKALRILQNEPLPERLEVNGRESEEEN 99
           PV   L+ + + V GQ F G G T++ AK  AA KALR     P                
Sbjct: 103 PVHAPLFVMSVEVNGQVFEGSGPTKKKAKLHAAEKALRSFVQFP---------------- 146

Query: 100 LNKSEISQVFEIALKRNLPVNFESFPLKQVARESGPPHMKN-FVT--KVSVGEFVGEGEG 156
            N SE      +A+ R L VN + F   Q      P  + N F T  K     +VG    
Sbjct: 147 -NASEA----HLAMGRTLSVNTD-FTSDQA---DFPDTLFNGFETPDKAEPPFYVGSNGD 197

Query: 157 KSKKISKKNAAIAVLEELKKLPPLPAVERVKPRIKKKTKPIVKPQTSPEYGQGINPISRL 216
            S   S   +  A         P+PA       + +   P++ P   P    G NP+  L
Sbjct: 198 DSFSSSGDLSLSA--------SPVPA------SLAQPPLPVLPPFPPPS---GKNPVMIL 240

Query: 217 AQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNAAENMLEI 276
            +++   K     Y  L+E G    + FVM V V     EG+G NKK+AK  AA++ L  
Sbjct: 241 NELRPGLK-----YDFLSESGESHAKSFVMSVVVDGQFFEGSGRNKKLAKARAAQSALAA 295

Query: 277 LGFKVPQAQPTKPALKSE 294
           +        P++  + SE
Sbjct: 296 IFNLHLDQTPSRQPIPSE 313



 Score = 40.0 bits (92), Expect = 0.005
 Identities = 25/63 (39%), Positives = 34/63 (53%), Gaps = 2/63 (3%)

Query: 212 PISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNAAE 271
           P + L Q+ + K   +  YTLL++ G      FVM V+V     EG+G  KK AK +AAE
Sbjct: 79  PKNALMQLNEIKPGLQ--YTLLSQTGPVHAPLFVMSVEVNGQVFEGSGPTKKKAKLHAAE 136

Query: 272 NML 274
             L
Sbjct: 137 KAL 139



 Score = 32.7 bits (73), Expect = 0.79
 Identities = 18/47 (38%), Positives = 24/47 (51%)

Query: 132 ESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLP 178
           ++GP H   FV  V V   V EG G +KK +K +AA   L    + P
Sbjct: 100 QTGPVHAPLFVMSVEVNGQVFEGSGPTKKKAKLHAAEKALRSFVQFP 146


>gi|7669477 RNA-specific adenosine deaminase B1 isoform 2 [Homo
           sapiens]
          Length = 741

 Score = 56.2 bits (134), Expect = 7e-08
 Identities = 73/258 (28%), Positives = 103/258 (39%), Gaps = 50/258 (19%)

Query: 40  PVPPLLYQVELSVGGQQFNGKGKTRQAAKHDAAAKALRILQNEPLPERLEVNGRESEEEN 99
           PV   L+ + + V GQ F G G T++ AK  AA KALR     P                
Sbjct: 103 PVHAPLFVMSVEVNGQVFEGSGPTKKKAKLHAAEKALRSFVQFP---------------- 146

Query: 100 LNKSEISQVFEIALKRNLPVNFESFPLKQVARESGPPHMKN-FVT--KVSVGEFVGEGEG 156
            N SE      +A+ R L VN + F   Q      P  + N F T  K     +VG    
Sbjct: 147 -NASEA----HLAMGRTLSVNTD-FTSDQA---DFPDTLFNGFETPDKAEPPFYVGSNGD 197

Query: 157 KSKKISKKNAAIAVLEELKKLPPLPAVERVKPRIKKKTKPIVKPQTSPEYGQGINPISRL 216
            S   S   +  A         P+PA       + +   P++ P   P    G NP+  L
Sbjct: 198 DSFSSSGDLSLSA--------SPVPA------SLAQPPLPVLPPFPPPS---GKNPVMIL 240

Query: 217 AQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNAAENMLEI 276
            +++   K     Y  L+E G    + FVM V V     EG+G NKK+AK  AA++ L  
Sbjct: 241 NELRPGLK-----YDFLSESGESHAKSFVMSVVVDGQFFEGSGRNKKLAKARAAQSALAA 295

Query: 277 LGFKVPQAQPTKPALKSE 294
           +        P++  + SE
Sbjct: 296 IFNLHLDQTPSRQPIPSE 313



 Score = 40.0 bits (92), Expect = 0.005
 Identities = 25/63 (39%), Positives = 34/63 (53%), Gaps = 2/63 (3%)

Query: 212 PISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNAAE 271
           P + L Q+ + K   +  YTLL++ G      FVM V+V     EG+G  KK AK +AAE
Sbjct: 79  PKNALMQLNEIKPGLQ--YTLLSQTGPVHAPLFVMSVEVNGQVFEGSGPTKKKAKLHAAE 136

Query: 272 NML 274
             L
Sbjct: 137 KAL 139



 Score = 32.7 bits (73), Expect = 0.79
 Identities = 18/47 (38%), Positives = 24/47 (51%)

Query: 132 ESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLP 178
           ++GP H   FV  V V   V EG G +KK +K +AA   L    + P
Sbjct: 100 QTGPVHAPLFVMSVEVNGQVFEGSGPTKKKAKLHAAEKALRSFVQFP 146


>gi|4501919 RNA-specific adenosine deaminase B1 isoform 1 [Homo
           sapiens]
          Length = 701

 Score = 56.2 bits (134), Expect = 7e-08
 Identities = 73/258 (28%), Positives = 103/258 (39%), Gaps = 50/258 (19%)

Query: 40  PVPPLLYQVELSVGGQQFNGKGKTRQAAKHDAAAKALRILQNEPLPERLEVNGRESEEEN 99
           PV   L+ + + V GQ F G G T++ AK  AA KALR     P                
Sbjct: 103 PVHAPLFVMSVEVNGQVFEGSGPTKKKAKLHAAEKALRSFVQFP---------------- 146

Query: 100 LNKSEISQVFEIALKRNLPVNFESFPLKQVARESGPPHMKN-FVT--KVSVGEFVGEGEG 156
            N SE      +A+ R L VN + F   Q      P  + N F T  K     +VG    
Sbjct: 147 -NASEA----HLAMGRTLSVNTD-FTSDQA---DFPDTLFNGFETPDKAEPPFYVGSNGD 197

Query: 157 KSKKISKKNAAIAVLEELKKLPPLPAVERVKPRIKKKTKPIVKPQTSPEYGQGINPISRL 216
            S   S   +  A         P+PA       + +   P++ P   P    G NP+  L
Sbjct: 198 DSFSSSGDLSLSA--------SPVPA------SLAQPPLPVLPPFPPPS---GKNPVMIL 240

Query: 217 AQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNAAENMLEI 276
            +++   K     Y  L+E G    + FVM V V     EG+G NKK+AK  AA++ L  
Sbjct: 241 NELRPGLK-----YDFLSESGESHAKSFVMSVVVDGQFFEGSGRNKKLAKARAAQSALAA 295

Query: 277 LGFKVPQAQPTKPALKSE 294
           +        P++  + SE
Sbjct: 296 IFNLHLDQTPSRQPIPSE 313



 Score = 40.0 bits (92), Expect = 0.005
 Identities = 25/63 (39%), Positives = 34/63 (53%), Gaps = 2/63 (3%)

Query: 212 PISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNAAE 271
           P + L Q+ + K   +  YTLL++ G      FVM V+V     EG+G  KK AK +AAE
Sbjct: 79  PKNALMQLNEIKPGLQ--YTLLSQTGPVHAPLFVMSVEVNGQVFEGSGPTKKKAKLHAAE 136

Query: 272 NML 274
             L
Sbjct: 137 KAL 139



 Score = 32.7 bits (73), Expect = 0.79
 Identities = 18/47 (38%), Positives = 24/47 (51%)

Query: 132 ESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLP 178
           ++GP H   FV  V V   V EG G +KK +K +AA   L    + P
Sbjct: 100 QTGPVHAPLFVMSVEVNGQVFEGSGPTKKKAKLHAAEKALRSFVQFP 146


>gi|21361745 spermatid perinuclear RNA binding protein [Homo
           sapiens]
          Length = 672

 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 66/278 (23%), Positives = 108/278 (38%), Gaps = 57/278 (20%)

Query: 64  RQAAKHDAAAKALRILQNEPLPERL---EVNGRESEEENLNKSEISQVFEIAL------- 113
           + A +  A  +  ++L+ +PLP      + +   +++E    S + + FE  L       
Sbjct: 311 QHALRLSAFGQIYKVLEMDPLPSSKPFQKYSWSVTDKEGAGSSALKRPFEDGLGDDKDPN 370

Query: 114 ---KRNLPVNFESFPLK-----------------QVARESGPPHMKNFVTKVSVGEFVGE 153
              KRNL    +S  +                  ++  +SGP H   F   V V     E
Sbjct: 371 KKMKRNLRKILDSKAIDLMNALMRLNQIRPGLQYKLLSQSGPVHAPVFTMSVDVDGTTYE 430

Query: 154 GEGKSKKISKKNAAIAVLEEL-------KKLPPLPAVERVKPRIKKKTKPIVKPQTSPEY 206
             G SKK +K + A+ VL+ +         +  + + E+     K +T   V   +S   
Sbjct: 431 ASGPSKKTAKLHVAVKVLQAMGYPTGFDADIECMSSDEKSDNESKNET---VSSNSSNNT 487

Query: 207 GQGINPISRLAQIQQA----------------KKEKEPEYTLLTERGLPRRREFVMQVKV 250
           G      S   +++                  +K +  +Y L++E G    + FVM+V+V
Sbjct: 488 GNSTTETSSTLEVRTQGPILTASGKNPVMELNEKRRGLKYELISETGGSHDKRFVMEVEV 547

Query: 251 GNHTAEGTGTNKKVAKRNAAENMLEILGFKVPQAQPTK 288
                 G G NKKVAK +AA   LE L F  P A   K
Sbjct: 548 DGQKFRGAGPNKKVAKASAALAALEKL-FSGPNAANNK 584



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 49/193 (25%), Positives = 83/193 (43%), Gaps = 32/193 (16%)

Query: 40  PVPPLLYQVELSVGGQQFNGKGKTRQAAKHDAAAKALRILQNEPLPERLEVNGRESEEEN 99
           PV   ++ + + V G  +   G +++ AK   A K L+ +   P     ++    S+E++
Sbjct: 412 PVHAPVFTMSVDVDGTTYEASGPSKKTAKLHVAVKVLQAM-GYPTGFDADIECMSSDEKS 470

Query: 100 LNKS------------------EISQVFEI--------ALKRN--LPVNFESFPLK-QVA 130
            N+S                  E S   E+        A  +N  + +N +   LK ++ 
Sbjct: 471 DNESKNETVSSNSSNNTGNSTTETSSTLEVRTQGPILTASGKNPVMELNEKRRGLKYELI 530

Query: 131 RESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLPPLPAVERVKPRI 190
            E+G  H K FV +V V      G G +KK++K +AA+A LE+L   P   A    K +I
Sbjct: 531 SETGGSHDKRFVMEVEVDGQKFRGAGPNKKVAKASAALAALEKLFSGP--NAANNKKKKI 588

Query: 191 KKKTKPIVKPQTS 203
             + K +V    S
Sbjct: 589 IPQAKGVVNTAVS 601


>gi|208431829 eukaryotic translation initiation factor 2-alpha
           kinase 2 isoform b [Homo sapiens]
          Length = 510

 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 48/164 (29%), Positives = 72/164 (43%), Gaps = 30/164 (18%)

Query: 114 KRNLPVNFESFPLKQVARESGPPHMKNFVTKVSV-GEFVGEGEGKSKKISKKNAAIAVLE 172
           K+ + + ++  P       SGPPH + F  +V + G    EGEG+SKK +K  AA   +E
Sbjct: 20  KQGVVLKYQELP------NSGPPHDRRFTFQVIIDGREFPEGEGRSKKEAKNAAAKLAVE 73

Query: 173 ELKKLPPLPAVERVKPRIKKKTKPIVKPQTSP----EYGQGINPISRLAQIQQAKKEKEP 228
            L K              KK   P++   T+       G  I  I+R+AQ    KK    
Sbjct: 74  ILNK-------------EKKAVSPLLLTTTNSSEGLSMGNYIGLINRIAQ----KKRLTV 116

Query: 229 EYTLLTERGLPRRREFVMQVKVG-NHTAEGTGTNKKVAKRNAAE 271
            Y      G+     F  + K+G    + GTG+ K+ AK+ AA+
Sbjct: 117 NYEQCAS-GVHGPEGFHYKCKMGQKEYSIGTGSTKQEAKQLAAK 159



 Score = 33.9 bits (76), Expect = 0.35
 Identities = 22/59 (37%), Positives = 28/59 (47%), Gaps = 1/59 (1%)

Query: 229 EYTLLTERGLPRRREFVMQVKV-GNHTAEGTGTNKKVAKRNAAENMLEILGFKVPQAQP 286
           +Y  L   G P  R F  QV + G    EG G +KK AK  AA+  +EIL  +     P
Sbjct: 26  KYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSKKEAKNAAAKLAVEILNKEKKAVSP 84


>gi|208431827 eukaryotic translation initiation factor 2-alpha
           kinase 2 isoform a [Homo sapiens]
          Length = 551

 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 48/164 (29%), Positives = 72/164 (43%), Gaps = 30/164 (18%)

Query: 114 KRNLPVNFESFPLKQVARESGPPHMKNFVTKVSV-GEFVGEGEGKSKKISKKNAAIAVLE 172
           K+ + + ++  P       SGPPH + F  +V + G    EGEG+SKK +K  AA   +E
Sbjct: 20  KQGVVLKYQELP------NSGPPHDRRFTFQVIIDGREFPEGEGRSKKEAKNAAAKLAVE 73

Query: 173 ELKKLPPLPAVERVKPRIKKKTKPIVKPQTSP----EYGQGINPISRLAQIQQAKKEKEP 228
            L K              KK   P++   T+       G  I  I+R+AQ    KK    
Sbjct: 74  ILNK-------------EKKAVSPLLLTTTNSSEGLSMGNYIGLINRIAQ----KKRLTV 116

Query: 229 EYTLLTERGLPRRREFVMQVKVG-NHTAEGTGTNKKVAKRNAAE 271
            Y      G+     F  + K+G    + GTG+ K+ AK+ AA+
Sbjct: 117 NYEQCAS-GVHGPEGFHYKCKMGQKEYSIGTGSTKQEAKQLAAK 159



 Score = 33.9 bits (76), Expect = 0.35
 Identities = 22/59 (37%), Positives = 28/59 (47%), Gaps = 1/59 (1%)

Query: 229 EYTLLTERGLPRRREFVMQVKV-GNHTAEGTGTNKKVAKRNAAENMLEILGFKVPQAQP 286
           +Y  L   G P  R F  QV + G    EG G +KK AK  AA+  +EIL  +     P
Sbjct: 26  KYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSKKEAKNAAAKLAVEILNKEKKAVSP 84


>gi|4506103 eukaryotic translation initiation factor 2-alpha kinase
           2 isoform a [Homo sapiens]
          Length = 551

 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 48/164 (29%), Positives = 72/164 (43%), Gaps = 30/164 (18%)

Query: 114 KRNLPVNFESFPLKQVARESGPPHMKNFVTKVSV-GEFVGEGEGKSKKISKKNAAIAVLE 172
           K+ + + ++  P       SGPPH + F  +V + G    EGEG+SKK +K  AA   +E
Sbjct: 20  KQGVVLKYQELP------NSGPPHDRRFTFQVIIDGREFPEGEGRSKKEAKNAAAKLAVE 73

Query: 173 ELKKLPPLPAVERVKPRIKKKTKPIVKPQTSP----EYGQGINPISRLAQIQQAKKEKEP 228
            L K              KK   P++   T+       G  I  I+R+AQ    KK    
Sbjct: 74  ILNK-------------EKKAVSPLLLTTTNSSEGLSMGNYIGLINRIAQ----KKRLTV 116

Query: 229 EYTLLTERGLPRRREFVMQVKVG-NHTAEGTGTNKKVAKRNAAE 271
            Y      G+     F  + K+G    + GTG+ K+ AK+ AA+
Sbjct: 117 NYEQCAS-GVHGPEGFHYKCKMGQKEYSIGTGSTKQEAKQLAAK 159



 Score = 33.9 bits (76), Expect = 0.35
 Identities = 22/59 (37%), Positives = 28/59 (47%), Gaps = 1/59 (1%)

Query: 229 EYTLLTERGLPRRREFVMQVKV-GNHTAEGTGTNKKVAKRNAAENMLEILGFKVPQAQP 286
           +Y  L   G P  R F  QV + G    EG G +KK AK  AA+  +EIL  +     P
Sbjct: 26  KYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSKKEAKNAAAKLAVEILNKEKKAVSP 84


>gi|8922077 adenosine deaminase, RNA-specific, B2 [Homo sapiens]
          Length = 739

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 49/208 (23%), Positives = 73/208 (35%), Gaps = 58/208 (27%)

Query: 132 ESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLP------------- 178
           ++GP H   F   V V     EG G +KK +K  AA   L    + P             
Sbjct: 147 QTGPVHAPVFAVAVEVNGLTFEGTGPTKKKAKMRAAELALRSFVQFPNACQAHLAMGGGP 206

Query: 179 -------------------------PLPAVERVKP-------------RIKKKTKPIVKP 200
                                    P P +   +P             R+  +   +V P
Sbjct: 207 GPGTDFTSDQADFPDTLFQEFEPPAPRPGLAGGRPGDAALLSAAYGRRRLLCRALDLVGP 266

Query: 201 QTSPEYGQGI-NPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTG 259
             +     G  NP+  L +++   +     Y  L E    R R FVM V V   T EG+G
Sbjct: 267 TPATPAAPGERNPVVLLNRLRAGLR-----YVCLAEPAERRARSFVMAVSVDGRTFEGSG 321

Query: 260 TNKKVAKRNAAENML-EILGFKVPQAQP 286
            +KK+A+  AA+  L E+   ++P   P
Sbjct: 322 RSKKLARGQAAQAALQELFDIQMPGHAP 349



 Score = 32.3 bits (72), Expect = 1.0
 Identities = 20/62 (32%), Positives = 31/62 (50%), Gaps = 2/62 (3%)

Query: 210 INPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNA 269
           + P + L Q+ + +   +  Y  +++ G      F + V+V   T EGTG  KK AK  A
Sbjct: 124 VAPKNALVQLHELRPGLQ--YRTVSQTGPVHAPVFAVAVEVNGLTFEGTGPTKKKAKMRA 181

Query: 270 AE 271
           AE
Sbjct: 182 AE 183



 Score = 29.6 bits (65), Expect = 6.7
 Identities = 16/38 (42%), Positives = 21/38 (55%)

Query: 40  PVPPLLYQVELSVGGQQFNGKGKTRQAAKHDAAAKALR 77
           PV   ++ V + V G  F G G T++ AK  AA  ALR
Sbjct: 150 PVHAPVFAVAVEVNGLTFEGTGPTKKKAKMRAAELALR 187


>gi|70167032 adenosine deaminase, RNA-specific isoform c [Homo
           sapiens]
          Length = 1181

 Score = 39.7 bits (91), Expect = 0.006
 Identities = 60/251 (23%), Positives = 104/251 (41%), Gaps = 31/251 (12%)

Query: 46  YQVELSVGGQQFN-GKGKTRQAAKHDAAAKALRILQNEPLPE---RLEVNGRESEEENLN 101
           ++ ++ + G++F   +  +++ AK DAA KA+ IL  E   +   + E +   S E+   
Sbjct: 535 FKFQVVINGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDSGKSEESSHYSTEKESE 594

Query: 102 KSEISQVFEIA----LKRNLPVNF---------ESFPLKQVARESGPPHMKNFVTKVSVG 148
           K+  SQ    +         PV            S   + +++E GP H   F   V+VG
Sbjct: 595 KTAESQTPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKE-GPAHEPKFQYCVAVG 653

Query: 149 -EFVGEGEGKSKKISKKNAAIAVLEELKKLPPLPAVERVKPRIKKKTKPIVKPQTSPEYG 207
            +        SKK++K+ AA    E +K L              +K   +V+   +    
Sbjct: 654 AQTFPSVSAPSKKVAKQMAAE---EAMKALHGEATNSMASDNQVRKIGELVRYLNT---- 706

Query: 208 QGINPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGT-GTNKKVAK 266
              NP+  L +  ++      E+ L+ + G P   +FV Q KVG          +KK  K
Sbjct: 707 ---NPVGGLLEYARSHGFAA-EFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGK 762

Query: 267 RNAAENMLEIL 277
           + AA+  L +L
Sbjct: 763 QEAADAALRVL 773


>gi|70167113 adenosine deaminase, RNA-specific isoform d [Homo
           sapiens]
          Length = 931

 Score = 38.5 bits (88), Expect = 0.014
 Identities = 61/267 (22%), Positives = 108/267 (40%), Gaps = 44/267 (16%)

Query: 46  YQVELSVGGQQFN-GKGKTRQAAKHDAAAKALRILQNEPLPE---RLEVNGRESEEENLN 101
           ++ ++ + G++F   +  +++ AK DAA KA+ IL  E   +   + E +   S E+   
Sbjct: 240 FKFQVVINGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDSGKSEESSHYSTEKESE 299

Query: 102 KSEISQVFEIA----LKRNLPVNF---------ESFPLKQVARESGPPHMKNFVTKVSVG 148
           K+  SQ    +         PV            S   + +++E GP H   F   V+VG
Sbjct: 300 KTAESQTPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKE-GPAHEPKFQYCVAVG 358

Query: 149 -EFVGEGEGKSKKISKKNAAIAVLEELKK----------------LPPLPAVERVKPRIK 191
            +        SKK++K+ AA   ++ L                     L  +E + P   
Sbjct: 359 AQTFPSVSAPSKKVAKQMAAEEAMKALHGEATNSMASDNQPEGMISESLDNLESMMPNKV 418

Query: 192 KKTKPIVKPQTSPEYGQGINPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVG 251
           +K   +V+   +       NP+  L +  ++      E+ L+ + G P   +FV Q KVG
Sbjct: 419 RKIGELVRYLNT-------NPVGGLLEYARSHGFAA-EFKLVDQSGPPHEPKFVYQAKVG 470

Query: 252 NHTAEGT-GTNKKVAKRNAAENMLEIL 277
                     +KK  K+ AA+  L +L
Sbjct: 471 GRWFPAVCAHSKKQGKQEAADAALRVL 497


>gi|70166944 adenosine deaminase, RNA-specific isoform b [Homo
           sapiens]
          Length = 1200

 Score = 38.5 bits (88), Expect = 0.014
 Identities = 61/267 (22%), Positives = 108/267 (40%), Gaps = 44/267 (16%)

Query: 46  YQVELSVGGQQFN-GKGKTRQAAKHDAAAKALRILQNEPLPE---RLEVNGRESEEENLN 101
           ++ ++ + G++F   +  +++ AK DAA KA+ IL  E   +   + E +   S E+   
Sbjct: 535 FKFQVVINGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDSGKSEESSHYSTEKESE 594

Query: 102 KSEISQVFEIA----LKRNLPVNF---------ESFPLKQVARESGPPHMKNFVTKVSVG 148
           K+  SQ    +         PV            S   + +++E GP H   F   V+VG
Sbjct: 595 KTAESQTPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKE-GPAHEPKFQYCVAVG 653

Query: 149 -EFVGEGEGKSKKISKKNAAIAVLEELKK----------------LPPLPAVERVKPRIK 191
            +        SKK++K+ AA   ++ L                     L  +E + P   
Sbjct: 654 AQTFPSVSAPSKKVAKQMAAEEAMKALHGEATNSMASDNQPEGMISESLDNLESMMPNKV 713

Query: 192 KKTKPIVKPQTSPEYGQGINPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVG 251
           +K   +V+   +       NP+  L +  ++      E+ L+ + G P   +FV Q KVG
Sbjct: 714 RKIGELVRYLNT-------NPVGGLLEYARSHGFAA-EFKLVDQSGPPHEPKFVYQAKVG 765

Query: 252 NHTAEGT-GTNKKVAKRNAAENMLEIL 277
                     +KK  K+ AA+  L +L
Sbjct: 766 GRWFPAVCAHSKKQGKQEAADAALRVL 792


>gi|70166852 adenosine deaminase, RNA-specific isoform a [Homo
           sapiens]
          Length = 1226

 Score = 38.5 bits (88), Expect = 0.014
 Identities = 61/267 (22%), Positives = 108/267 (40%), Gaps = 44/267 (16%)

Query: 46  YQVELSVGGQQFN-GKGKTRQAAKHDAAAKALRILQNEPLPE---RLEVNGRESEEENLN 101
           ++ ++ + G++F   +  +++ AK DAA KA+ IL  E   +   + E +   S E+   
Sbjct: 535 FKFQVVINGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDSGKSEESSHYSTEKESE 594

Query: 102 KSEISQVFEIA----LKRNLPVNF---------ESFPLKQVARESGPPHMKNFVTKVSVG 148
           K+  SQ    +         PV            S   + +++E GP H   F   V+VG
Sbjct: 595 KTAESQTPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKE-GPAHEPKFQYCVAVG 653

Query: 149 -EFVGEGEGKSKKISKKNAAIAVLEELKK----------------LPPLPAVERVKPRIK 191
            +        SKK++K+ AA   ++ L                     L  +E + P   
Sbjct: 654 AQTFPSVSAPSKKVAKQMAAEEAMKALHGEATNSMASDNQPEGMISESLDNLESMMPNKV 713

Query: 192 KKTKPIVKPQTSPEYGQGINPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVG 251
           +K   +V+   +       NP+  L +  ++      E+ L+ + G P   +FV Q KVG
Sbjct: 714 RKIGELVRYLNT-------NPVGGLLEYARSHGFAA-EFKLVDQSGPPHEPKFVYQAKVG 765

Query: 252 NHTAEGT-GTNKKVAKRNAAENMLEIL 277
                     +KK  K+ AA+  L +L
Sbjct: 766 GRWFPAVCAHSKKQGKQEAADAALRVL 792


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.132    0.377 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,642,727
Number of Sequences: 37866
Number of extensions: 1067021
Number of successful extensions: 2688
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 30
Number of HSP's successfully gapped in prelim test: 60
Number of HSP's that attempted gapping in prelim test: 2495
Number of HSP's gapped (non-prelim): 202
length of query: 502
length of database: 18,247,518
effective HSP length: 107
effective length of query: 395
effective length of database: 14,195,856
effective search space: 5607363120
effective search space used: 5607363120
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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