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Search of human proteins with 82659089
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|82659089 staufen isoform a [Homo sapiens]
(496 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|82659089 staufen isoform a [Homo sapiens] 999 0.0
gi|82659087 staufen isoform b [Homo sapiens] 999 0.0
gi|82659085 staufen isoform a [Homo sapiens] 999 0.0
gi|82659083 staufen isoform a [Homo sapiens] 999 0.0
gi|82659091 staufen isoform c [Homo sapiens] 992 0.0
gi|7657625 staufen homolog 2 [Homo sapiens] 370 e-102
gi|19743838 TAR RNA binding protein 2 isoform b [Homo sapiens] 79 1e-14
gi|19743840 TAR RNA binding protein 2 isoform a [Homo sapiens] 79 1e-14
gi|85068512 TAR RNA binding protein 2 isoform b [Homo sapiens] 79 1e-14
gi|213417919 protein kinase, interferon-inducible double strande... 74 3e-13
gi|213417911 protein kinase, interferon-inducible double strande... 74 3e-13
gi|4505581 protein kinase, interferon-inducible double stranded ... 74 3e-13
gi|24234756 interleukin enhancer binding factor 3 isoform c [Hom... 60 3e-09
gi|24234753 interleukin enhancer binding factor 3 isoform b [Hom... 60 3e-09
gi|24234750 interleukin enhancer binding factor 3 isoform a [Hom... 60 3e-09
gi|212549555 interleukin enhancer binding factor 3 isoform e [Ho... 60 5e-09
gi|212549553 interleukin enhancer binding factor 3 isoform d [Ho... 60 5e-09
gi|237681091 RNA-specific adenosine deaminase B1 isoform 7 [Homo... 60 6e-09
gi|7669479 RNA-specific adenosine deaminase B1 isoform 3 [Homo s... 60 6e-09
gi|7669477 RNA-specific adenosine deaminase B1 isoform 2 [Homo s... 60 6e-09
gi|4501919 RNA-specific adenosine deaminase B1 isoform 1 [Homo s... 60 6e-09
gi|70167113 adenosine deaminase, RNA-specific isoform d [Homo sa... 56 7e-08
gi|70167032 adenosine deaminase, RNA-specific isoform c [Homo sa... 56 7e-08
gi|70166944 adenosine deaminase, RNA-specific isoform b [Homo sa... 56 7e-08
gi|70166852 adenosine deaminase, RNA-specific isoform a [Homo sa... 56 7e-08
gi|21361745 spermatid perinuclear RNA binding protein [Homo sapi... 56 9e-08
gi|208431829 eukaryotic translation initiation factor 2-alpha ki... 46 7e-05
gi|208431827 eukaryotic translation initiation factor 2-alpha ki... 46 7e-05
gi|4506103 eukaryotic translation initiation factor 2-alpha kina... 46 7e-05
gi|8922077 adenosine deaminase, RNA-specific, B2 [Homo sapiens] 44 4e-04
>gi|82659089 staufen isoform a [Homo sapiens]
Length = 496
Score = 999 bits (2582), Expect = 0.0
Identities = 496/496 (100%), Positives = 496/496 (100%)
Query: 1 MKLGKKPMYKPVDPYSRMQSTYNYNMRGGAYPPRYFYPFPVPPLLYQVELSVGGQQFNGK 60
MKLGKKPMYKPVDPYSRMQSTYNYNMRGGAYPPRYFYPFPVPPLLYQVELSVGGQQFNGK
Sbjct: 1 MKLGKKPMYKPVDPYSRMQSTYNYNMRGGAYPPRYFYPFPVPPLLYQVELSVGGQQFNGK 60
Query: 61 GKTRQAAKHDAAAKALRILQNEPLPERLEVNGRESEEENLNKSEISQVFEIALKRNLPVN 120
GKTRQAAKHDAAAKALRILQNEPLPERLEVNGRESEEENLNKSEISQVFEIALKRNLPVN
Sbjct: 61 GKTRQAAKHDAAAKALRILQNEPLPERLEVNGRESEEENLNKSEISQVFEIALKRNLPVN 120
Query: 121 FEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLPPLPAVERV 180
FEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLPPLPAVERV
Sbjct: 121 FEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLPPLPAVERV 180
Query: 181 KPRIKKKTKPIVKPQTSPEYGQGINPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVM 240
KPRIKKKTKPIVKPQTSPEYGQGINPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVM
Sbjct: 181 KPRIKKKTKPIVKPQTSPEYGQGINPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVM 240
Query: 241 QVKVGNHTAEGTGTNKKVAKRNAAENMLEILGFKVPQAQPTKPALKSEEKTPIKKPGDGR 300
QVKVGNHTAEGTGTNKKVAKRNAAENMLEILGFKVPQAQPTKPALKSEEKTPIKKPGDGR
Sbjct: 241 QVKVGNHTAEGTGTNKKVAKRNAAENMLEILGFKVPQAQPTKPALKSEEKTPIKKPGDGR 300
Query: 301 KVTFFEPGSGDENGTSNKEDEFRMPYLSHQQLPAGILPMVPEVAQAVGVSQGHHTKDFTR 360
KVTFFEPGSGDENGTSNKEDEFRMPYLSHQQLPAGILPMVPEVAQAVGVSQGHHTKDFTR
Sbjct: 301 KVTFFEPGSGDENGTSNKEDEFRMPYLSHQQLPAGILPMVPEVAQAVGVSQGHHTKDFTR 360
Query: 361 AAPNPAKATVTAMIARELLYGGTSPTAETILKNNISSGHVPHGPLTRPSEQLDYLSRVQG 420
AAPNPAKATVTAMIARELLYGGTSPTAETILKNNISSGHVPHGPLTRPSEQLDYLSRVQG
Sbjct: 361 AAPNPAKATVTAMIARELLYGGTSPTAETILKNNISSGHVPHGPLTRPSEQLDYLSRVQG 420
Query: 421 FQVEYKDFPKNNKNEFVSLINCSSQPPLISHGIGKDVESCHDMAALNILKLLSELDQQST 480
FQVEYKDFPKNNKNEFVSLINCSSQPPLISHGIGKDVESCHDMAALNILKLLSELDQQST
Sbjct: 421 FQVEYKDFPKNNKNEFVSLINCSSQPPLISHGIGKDVESCHDMAALNILKLLSELDQQST 480
Query: 481 EMPRTGNGPMSVCGRC 496
EMPRTGNGPMSVCGRC
Sbjct: 481 EMPRTGNGPMSVCGRC 496
>gi|82659087 staufen isoform b [Homo sapiens]
Length = 577
Score = 999 bits (2582), Expect = 0.0
Identities = 496/496 (100%), Positives = 496/496 (100%)
Query: 1 MKLGKKPMYKPVDPYSRMQSTYNYNMRGGAYPPRYFYPFPVPPLLYQVELSVGGQQFNGK 60
MKLGKKPMYKPVDPYSRMQSTYNYNMRGGAYPPRYFYPFPVPPLLYQVELSVGGQQFNGK
Sbjct: 82 MKLGKKPMYKPVDPYSRMQSTYNYNMRGGAYPPRYFYPFPVPPLLYQVELSVGGQQFNGK 141
Query: 61 GKTRQAAKHDAAAKALRILQNEPLPERLEVNGRESEEENLNKSEISQVFEIALKRNLPVN 120
GKTRQAAKHDAAAKALRILQNEPLPERLEVNGRESEEENLNKSEISQVFEIALKRNLPVN
Sbjct: 142 GKTRQAAKHDAAAKALRILQNEPLPERLEVNGRESEEENLNKSEISQVFEIALKRNLPVN 201
Query: 121 FEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLPPLPAVERV 180
FEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLPPLPAVERV
Sbjct: 202 FEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLPPLPAVERV 261
Query: 181 KPRIKKKTKPIVKPQTSPEYGQGINPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVM 240
KPRIKKKTKPIVKPQTSPEYGQGINPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVM
Sbjct: 262 KPRIKKKTKPIVKPQTSPEYGQGINPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVM 321
Query: 241 QVKVGNHTAEGTGTNKKVAKRNAAENMLEILGFKVPQAQPTKPALKSEEKTPIKKPGDGR 300
QVKVGNHTAEGTGTNKKVAKRNAAENMLEILGFKVPQAQPTKPALKSEEKTPIKKPGDGR
Sbjct: 322 QVKVGNHTAEGTGTNKKVAKRNAAENMLEILGFKVPQAQPTKPALKSEEKTPIKKPGDGR 381
Query: 301 KVTFFEPGSGDENGTSNKEDEFRMPYLSHQQLPAGILPMVPEVAQAVGVSQGHHTKDFTR 360
KVTFFEPGSGDENGTSNKEDEFRMPYLSHQQLPAGILPMVPEVAQAVGVSQGHHTKDFTR
Sbjct: 382 KVTFFEPGSGDENGTSNKEDEFRMPYLSHQQLPAGILPMVPEVAQAVGVSQGHHTKDFTR 441
Query: 361 AAPNPAKATVTAMIARELLYGGTSPTAETILKNNISSGHVPHGPLTRPSEQLDYLSRVQG 420
AAPNPAKATVTAMIARELLYGGTSPTAETILKNNISSGHVPHGPLTRPSEQLDYLSRVQG
Sbjct: 442 AAPNPAKATVTAMIARELLYGGTSPTAETILKNNISSGHVPHGPLTRPSEQLDYLSRVQG 501
Query: 421 FQVEYKDFPKNNKNEFVSLINCSSQPPLISHGIGKDVESCHDMAALNILKLLSELDQQST 480
FQVEYKDFPKNNKNEFVSLINCSSQPPLISHGIGKDVESCHDMAALNILKLLSELDQQST
Sbjct: 502 FQVEYKDFPKNNKNEFVSLINCSSQPPLISHGIGKDVESCHDMAALNILKLLSELDQQST 561
Query: 481 EMPRTGNGPMSVCGRC 496
EMPRTGNGPMSVCGRC
Sbjct: 562 EMPRTGNGPMSVCGRC 577
>gi|82659085 staufen isoform a [Homo sapiens]
Length = 496
Score = 999 bits (2582), Expect = 0.0
Identities = 496/496 (100%), Positives = 496/496 (100%)
Query: 1 MKLGKKPMYKPVDPYSRMQSTYNYNMRGGAYPPRYFYPFPVPPLLYQVELSVGGQQFNGK 60
MKLGKKPMYKPVDPYSRMQSTYNYNMRGGAYPPRYFYPFPVPPLLYQVELSVGGQQFNGK
Sbjct: 1 MKLGKKPMYKPVDPYSRMQSTYNYNMRGGAYPPRYFYPFPVPPLLYQVELSVGGQQFNGK 60
Query: 61 GKTRQAAKHDAAAKALRILQNEPLPERLEVNGRESEEENLNKSEISQVFEIALKRNLPVN 120
GKTRQAAKHDAAAKALRILQNEPLPERLEVNGRESEEENLNKSEISQVFEIALKRNLPVN
Sbjct: 61 GKTRQAAKHDAAAKALRILQNEPLPERLEVNGRESEEENLNKSEISQVFEIALKRNLPVN 120
Query: 121 FEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLPPLPAVERV 180
FEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLPPLPAVERV
Sbjct: 121 FEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLPPLPAVERV 180
Query: 181 KPRIKKKTKPIVKPQTSPEYGQGINPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVM 240
KPRIKKKTKPIVKPQTSPEYGQGINPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVM
Sbjct: 181 KPRIKKKTKPIVKPQTSPEYGQGINPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVM 240
Query: 241 QVKVGNHTAEGTGTNKKVAKRNAAENMLEILGFKVPQAQPTKPALKSEEKTPIKKPGDGR 300
QVKVGNHTAEGTGTNKKVAKRNAAENMLEILGFKVPQAQPTKPALKSEEKTPIKKPGDGR
Sbjct: 241 QVKVGNHTAEGTGTNKKVAKRNAAENMLEILGFKVPQAQPTKPALKSEEKTPIKKPGDGR 300
Query: 301 KVTFFEPGSGDENGTSNKEDEFRMPYLSHQQLPAGILPMVPEVAQAVGVSQGHHTKDFTR 360
KVTFFEPGSGDENGTSNKEDEFRMPYLSHQQLPAGILPMVPEVAQAVGVSQGHHTKDFTR
Sbjct: 301 KVTFFEPGSGDENGTSNKEDEFRMPYLSHQQLPAGILPMVPEVAQAVGVSQGHHTKDFTR 360
Query: 361 AAPNPAKATVTAMIARELLYGGTSPTAETILKNNISSGHVPHGPLTRPSEQLDYLSRVQG 420
AAPNPAKATVTAMIARELLYGGTSPTAETILKNNISSGHVPHGPLTRPSEQLDYLSRVQG
Sbjct: 361 AAPNPAKATVTAMIARELLYGGTSPTAETILKNNISSGHVPHGPLTRPSEQLDYLSRVQG 420
Query: 421 FQVEYKDFPKNNKNEFVSLINCSSQPPLISHGIGKDVESCHDMAALNILKLLSELDQQST 480
FQVEYKDFPKNNKNEFVSLINCSSQPPLISHGIGKDVESCHDMAALNILKLLSELDQQST
Sbjct: 421 FQVEYKDFPKNNKNEFVSLINCSSQPPLISHGIGKDVESCHDMAALNILKLLSELDQQST 480
Query: 481 EMPRTGNGPMSVCGRC 496
EMPRTGNGPMSVCGRC
Sbjct: 481 EMPRTGNGPMSVCGRC 496
>gi|82659083 staufen isoform a [Homo sapiens]
Length = 496
Score = 999 bits (2582), Expect = 0.0
Identities = 496/496 (100%), Positives = 496/496 (100%)
Query: 1 MKLGKKPMYKPVDPYSRMQSTYNYNMRGGAYPPRYFYPFPVPPLLYQVELSVGGQQFNGK 60
MKLGKKPMYKPVDPYSRMQSTYNYNMRGGAYPPRYFYPFPVPPLLYQVELSVGGQQFNGK
Sbjct: 1 MKLGKKPMYKPVDPYSRMQSTYNYNMRGGAYPPRYFYPFPVPPLLYQVELSVGGQQFNGK 60
Query: 61 GKTRQAAKHDAAAKALRILQNEPLPERLEVNGRESEEENLNKSEISQVFEIALKRNLPVN 120
GKTRQAAKHDAAAKALRILQNEPLPERLEVNGRESEEENLNKSEISQVFEIALKRNLPVN
Sbjct: 61 GKTRQAAKHDAAAKALRILQNEPLPERLEVNGRESEEENLNKSEISQVFEIALKRNLPVN 120
Query: 121 FEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLPPLPAVERV 180
FEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLPPLPAVERV
Sbjct: 121 FEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLPPLPAVERV 180
Query: 181 KPRIKKKTKPIVKPQTSPEYGQGINPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVM 240
KPRIKKKTKPIVKPQTSPEYGQGINPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVM
Sbjct: 181 KPRIKKKTKPIVKPQTSPEYGQGINPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVM 240
Query: 241 QVKVGNHTAEGTGTNKKVAKRNAAENMLEILGFKVPQAQPTKPALKSEEKTPIKKPGDGR 300
QVKVGNHTAEGTGTNKKVAKRNAAENMLEILGFKVPQAQPTKPALKSEEKTPIKKPGDGR
Sbjct: 241 QVKVGNHTAEGTGTNKKVAKRNAAENMLEILGFKVPQAQPTKPALKSEEKTPIKKPGDGR 300
Query: 301 KVTFFEPGSGDENGTSNKEDEFRMPYLSHQQLPAGILPMVPEVAQAVGVSQGHHTKDFTR 360
KVTFFEPGSGDENGTSNKEDEFRMPYLSHQQLPAGILPMVPEVAQAVGVSQGHHTKDFTR
Sbjct: 301 KVTFFEPGSGDENGTSNKEDEFRMPYLSHQQLPAGILPMVPEVAQAVGVSQGHHTKDFTR 360
Query: 361 AAPNPAKATVTAMIARELLYGGTSPTAETILKNNISSGHVPHGPLTRPSEQLDYLSRVQG 420
AAPNPAKATVTAMIARELLYGGTSPTAETILKNNISSGHVPHGPLTRPSEQLDYLSRVQG
Sbjct: 361 AAPNPAKATVTAMIARELLYGGTSPTAETILKNNISSGHVPHGPLTRPSEQLDYLSRVQG 420
Query: 421 FQVEYKDFPKNNKNEFVSLINCSSQPPLISHGIGKDVESCHDMAALNILKLLSELDQQST 480
FQVEYKDFPKNNKNEFVSLINCSSQPPLISHGIGKDVESCHDMAALNILKLLSELDQQST
Sbjct: 421 FQVEYKDFPKNNKNEFVSLINCSSQPPLISHGIGKDVESCHDMAALNILKLLSELDQQST 480
Query: 481 EMPRTGNGPMSVCGRC 496
EMPRTGNGPMSVCGRC
Sbjct: 481 EMPRTGNGPMSVCGRC 496
>gi|82659091 staufen isoform c [Homo sapiens]
Length = 502
Score = 992 bits (2565), Expect = 0.0
Identities = 496/502 (98%), Positives = 496/502 (98%), Gaps = 6/502 (1%)
Query: 1 MKLGKKPMYKPVDPYSRMQSTYNYNMRGGAYPPRYFYPFPVPPLLYQVELSVGGQQFNGK 60
MKLGKKPMYKPVDPYSRMQSTYNYNMRGGAYPPRYFYPFPVPPLLYQVELSVGGQQFNGK
Sbjct: 1 MKLGKKPMYKPVDPYSRMQSTYNYNMRGGAYPPRYFYPFPVPPLLYQVELSVGGQQFNGK 60
Query: 61 GKTRQAAKHDAAAKALRILQNEPLPERLEVNGRESEEENLNKSEISQVFEIALKRNLPVN 120
GKTRQAAKHDAAAKALRILQNEPLPERLEVNGRESEEENLNKSEISQVFEIALKRNLPVN
Sbjct: 61 GKTRQAAKHDAAAKALRILQNEPLPERLEVNGRESEEENLNKSEISQVFEIALKRNLPVN 120
Query: 121 FE------VARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLPPL 174
FE VARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLPPL
Sbjct: 121 FESFPLKQVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLPPL 180
Query: 175 PAVERVKPRIKKKTKPIVKPQTSPEYGQGINPISRLAQIQQAKKEKEPEYTLLTERGLPR 234
PAVERVKPRIKKKTKPIVKPQTSPEYGQGINPISRLAQIQQAKKEKEPEYTLLTERGLPR
Sbjct: 181 PAVERVKPRIKKKTKPIVKPQTSPEYGQGINPISRLAQIQQAKKEKEPEYTLLTERGLPR 240
Query: 235 RREFVMQVKVGNHTAEGTGTNKKVAKRNAAENMLEILGFKVPQAQPTKPALKSEEKTPIK 294
RREFVMQVKVGNHTAEGTGTNKKVAKRNAAENMLEILGFKVPQAQPTKPALKSEEKTPIK
Sbjct: 241 RREFVMQVKVGNHTAEGTGTNKKVAKRNAAENMLEILGFKVPQAQPTKPALKSEEKTPIK 300
Query: 295 KPGDGRKVTFFEPGSGDENGTSNKEDEFRMPYLSHQQLPAGILPMVPEVAQAVGVSQGHH 354
KPGDGRKVTFFEPGSGDENGTSNKEDEFRMPYLSHQQLPAGILPMVPEVAQAVGVSQGHH
Sbjct: 301 KPGDGRKVTFFEPGSGDENGTSNKEDEFRMPYLSHQQLPAGILPMVPEVAQAVGVSQGHH 360
Query: 355 TKDFTRAAPNPAKATVTAMIARELLYGGTSPTAETILKNNISSGHVPHGPLTRPSEQLDY 414
TKDFTRAAPNPAKATVTAMIARELLYGGTSPTAETILKNNISSGHVPHGPLTRPSEQLDY
Sbjct: 361 TKDFTRAAPNPAKATVTAMIARELLYGGTSPTAETILKNNISSGHVPHGPLTRPSEQLDY 420
Query: 415 LSRVQGFQVEYKDFPKNNKNEFVSLINCSSQPPLISHGIGKDVESCHDMAALNILKLLSE 474
LSRVQGFQVEYKDFPKNNKNEFVSLINCSSQPPLISHGIGKDVESCHDMAALNILKLLSE
Sbjct: 421 LSRVQGFQVEYKDFPKNNKNEFVSLINCSSQPPLISHGIGKDVESCHDMAALNILKLLSE 480
Query: 475 LDQQSTEMPRTGNGPMSVCGRC 496
LDQQSTEMPRTGNGPMSVCGRC
Sbjct: 481 LDQQSTEMPRTGNGPMSVCGRC 502
>gi|7657625 staufen homolog 2 [Homo sapiens]
Length = 479
Score = 370 bits (951), Expect = e-102
Identities = 231/442 (52%), Positives = 283/442 (64%), Gaps = 54/442 (12%)
Query: 1 MKLGKKPMYKPVDPYSRMQSTYNYNMRGGAYPPRYFYPFPVPPLLYQVELSVGGQQFNGK 60
MK G+ +Y+P+DP NYN RG Y RY P P ++ V+L+VG +F G+
Sbjct: 73 MKRGEPAIYRPLDPKPFPNYRANYNFRG-MYNQRYHCPVPK---IFYVQLTVGNNEFFGE 128
Query: 61 GKTRQAAKHDAAAKALRILQNEPLPERLEVNGRES----EEENLNKSEISQVFEIALKRN 116
GKTRQAA+H+AA KAL+ LQNEP+PER NG ++++ NKSEIS VFEIALKRN
Sbjct: 129 GKTRQAARHNAAMKALQALQNEPIPERSPQNGESGKDMDDDKDANKSEISLVFEIALKRN 188
Query: 117 LPVNFEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLPPLPA 176
+PV+FEV +ESGPPHMK+FVT+VSVGEF EGEG SKK+SKK AA VL+ELKKLPPLP
Sbjct: 189 MPVSFEVIKESGPPHMKSFVTRVSVGEFSAEGEGNSKKLSKKRAATTVLQELKKLPPLPV 248
Query: 177 VERVKPRIKKKTKPIVKPQTSPEYGQGINPISRLAQIQQAKKEKEPEYTLLTERGLPRRR 236
VE+ K KK+ K IVK PEYGQG+NPISRLAQIQQAKKEKEP+Y LL+ERG+PRRR
Sbjct: 249 VEKPKLFFKKRPKTIVK--AGPEYGQGMNPISRLAQIQQAKKEKEPDYVLLSERGMPRRR 306
Query: 237 EFVMQVKVGNHTAEGTGTNKKVAKRNAAENMLEILGFKVPQAQPTKPALKSEEKTPIKKP 296
EFVMQVKVGN A GTG NKK+AK+NAAE ML LG+K + EKT K
Sbjct: 307 EFVMQVKVGNEVATGTGPNKKIAKKNAAEAMLLQLGYKA-----STNLQDQLEKTGENKG 361
Query: 297 GDGRKVTFFEPGSGDENGTSNKEDEFRMPYLSHQQLPAGILPMVPEVAQAV--------- 347
G K F EP T+N P GIL + P+V Q +
Sbjct: 362 WSGPKPGFPEP-------TNN--------------TPKGILHLSPDVYQEMEASRHKVIS 400
Query: 348 GVSQGH-HTKDFTRAAPN----PAKATVTAMIARELLYGGTSPTAETI-LKNNISSGHVP 401
G + G+ KD + + + + +A IARELL GTS TAE I LK SS P
Sbjct: 401 GTTLGYLSPKDMNQPSSSFFSISPTSNSSATIARELLMNGTSSTAEAIGLKG--SSPTPP 458
Query: 402 HGPLTRPSEQLDYLSRVQGFQV 423
P+ +PS+QL+YL+R+QGFQV
Sbjct: 459 CSPV-QPSKQLEYLARIQGFQV 479
Score = 67.4 bits (163), Expect = 3e-11
Identities = 70/274 (25%), Positives = 120/274 (43%), Gaps = 39/274 (14%)
Query: 45 LYQVELSVGGQQFNGKGKTRQAAKHDAAAKALRILQNEPLPERLEVNGRESEEENLNKSE 104
++ V+LS+G Q + +G + + A+ A KA L LP+ V N N
Sbjct: 7 MFSVQLSLGEQTWESEGSSIKKAQQAVANKA---LTESTLPK--PVQKPPKSNVNNNPGS 61
Query: 105 ISQVFE---IALKRNLPVNFEVARESGPPHM-------------------KNFVTKVSVG 142
I+ E +A+KR P + P+ K F +++VG
Sbjct: 62 ITPTVELNGLAMKRGEPAIYRPLDPKPFPNYRANYNFRGMYNQRYHCPVPKIFYVQLTVG 121
Query: 143 EFVGEGEGKSKKISKKNAAIAVLEELKKLPPLPAVERVKPRIKKKTKPIVKPQTSPEYGQ 202
GEGK+++ ++ NAA+ L+ L+ P + P+ + K + + + +
Sbjct: 122 NNEFFGEGKTRQAARHNAAMKALQALQNEP----IPERSPQNGESGKDMDDDKDANK--- 174
Query: 203 GINPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRN 262
+ IS + +I K+ + ++ E G P + FV +V VG +AEG G +KK++K+
Sbjct: 175 --SEISLVFEI-ALKRNMPVSFEVIKESGPPHMKSFVTRVSVGEFSAEGEGNSKKLSKKR 231
Query: 263 AAENMLEILGFKVPQAQPTKPAL--KSEEKTPIK 294
AA +L+ L P KP L K KT +K
Sbjct: 232 AATTVLQELKKLPPLPVVEKPKLFFKKRPKTIVK 265
>gi|19743838 TAR RNA binding protein 2 isoform b [Homo sapiens]
Length = 345
Score = 78.6 bits (192), Expect = 1e-14
Identities = 58/198 (29%), Positives = 90/198 (45%), Gaps = 29/198 (14%)
Query: 99 NLNKSEISQVFEIALKRNLPVNFEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKK 158
N K+ IS + E + +++ + G H NF +V+VG+ G+G SKK +K
Sbjct: 5 NPGKTPISLLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTVGDTSCTGQGPSKKAAKH 64
Query: 159 NAAIAVLEELK------------------------KLPPLPAVERVKPR---IKKKTKPI 191
AA L+ LK +P A P + ++ P+
Sbjct: 65 KAAEVALKHLKGGSMLEPALEDSSSFSPLDSSLPEDIPVFTAAAAATPVPSVVLTRSPPM 124
Query: 192 -VKPQTSPEYGQGINPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAE 250
++P SP+ + NP+ L ++ K + PEYT+ E G R+EF M +V
Sbjct: 125 ELQPPVSPQQSE-CNPVGALQELVVQKGWRLPEYTVTQESGPAHRKEFTMTCRVERFIEI 183
Query: 251 GTGTNKKVAKRNAAENML 268
G+GT+KK+AKRNAA ML
Sbjct: 184 GSGTSKKLAKRNAAAKML 201
Score = 49.7 bits (117), Expect = 6e-06
Identities = 52/213 (24%), Positives = 87/213 (40%), Gaps = 55/213 (25%)
Query: 4 GKKPMYKPVDPYSRMQSTYNYNM---RGGAYPPRYFYPFPVPPLLYQVELSVGGQQFNGK 60
GK P+ + +R+ T Y++ G A+ P + + ++VG G+
Sbjct: 7 GKTPISLLQEYGTRIGKTPVYDLLKAEGQAHQPNFTF-----------RVTVGDTSCTGQ 55
Query: 61 GKTRQAAKHDAAAKALRILQNEPLPE-RLEVNGRESEEENLNKSEI---------SQVFE 110
G +++AAKH AA AL+ L+ + E LE + S ++ +I + V
Sbjct: 56 GPSKKAAKHKAAEVALKHLKGGSMLEPALEDSSSFSPLDSSLPEDIPVFTAAAAATPVPS 115
Query: 111 IALKRNLPVNFE-------------------------------VARESGPPHMKNFVTKV 139
+ L R+ P+ + V +ESGP H K F
Sbjct: 116 VVLTRSPPMELQPPVSPQQSECNPVGALQELVVQKGWRLPEYTVTQESGPAHRKEFTMTC 175
Query: 140 SVGEFVGEGEGKSKKISKKNAAIAVLEELKKLP 172
V F+ G G SKK++K+NAA +L + +P
Sbjct: 176 RVERFIEIGSGTSKKLAKRNAAAKMLLRVHTVP 208
Score = 40.0 bits (92), Expect = 0.005
Identities = 27/69 (39%), Positives = 34/69 (49%), Gaps = 1/69 (1%)
Query: 203 GINPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRN 262
G PIS L Q + K P Y LL G + F +V VG+ + G G +KK AK
Sbjct: 7 GKTPIS-LLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTVGDTSCTGQGPSKKAAKHK 65
Query: 263 AAENMLEIL 271
AAE L+ L
Sbjct: 66 AAEVALKHL 74
>gi|19743840 TAR RNA binding protein 2 isoform a [Homo sapiens]
Length = 366
Score = 78.6 bits (192), Expect = 1e-14
Identities = 58/198 (29%), Positives = 90/198 (45%), Gaps = 29/198 (14%)
Query: 99 NLNKSEISQVFEIALKRNLPVNFEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKK 158
N K+ IS + E + +++ + G H NF +V+VG+ G+G SKK +K
Sbjct: 26 NPGKTPISLLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTVGDTSCTGQGPSKKAAKH 85
Query: 159 NAAIAVLEELK------------------------KLPPLPAVERVKPR---IKKKTKPI 191
AA L+ LK +P A P + ++ P+
Sbjct: 86 KAAEVALKHLKGGSMLEPALEDSSSFSPLDSSLPEDIPVFTAAAAATPVPSVVLTRSPPM 145
Query: 192 -VKPQTSPEYGQGINPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAE 250
++P SP+ + NP+ L ++ K + PEYT+ E G R+EF M +V
Sbjct: 146 ELQPPVSPQQSE-CNPVGALQELVVQKGWRLPEYTVTQESGPAHRKEFTMTCRVERFIEI 204
Query: 251 GTGTNKKVAKRNAAENML 268
G+GT+KK+AKRNAA ML
Sbjct: 205 GSGTSKKLAKRNAAAKML 222
Score = 49.7 bits (117), Expect = 6e-06
Identities = 52/213 (24%), Positives = 87/213 (40%), Gaps = 55/213 (25%)
Query: 4 GKKPMYKPVDPYSRMQSTYNYNM---RGGAYPPRYFYPFPVPPLLYQVELSVGGQQFNGK 60
GK P+ + +R+ T Y++ G A+ P + + ++VG G+
Sbjct: 28 GKTPISLLQEYGTRIGKTPVYDLLKAEGQAHQPNFTF-----------RVTVGDTSCTGQ 76
Query: 61 GKTRQAAKHDAAAKALRILQNEPLPE-RLEVNGRESEEENLNKSEI---------SQVFE 110
G +++AAKH AA AL+ L+ + E LE + S ++ +I + V
Sbjct: 77 GPSKKAAKHKAAEVALKHLKGGSMLEPALEDSSSFSPLDSSLPEDIPVFTAAAAATPVPS 136
Query: 111 IALKRNLPVNFE-------------------------------VARESGPPHMKNFVTKV 139
+ L R+ P+ + V +ESGP H K F
Sbjct: 137 VVLTRSPPMELQPPVSPQQSECNPVGALQELVVQKGWRLPEYTVTQESGPAHRKEFTMTC 196
Query: 140 SVGEFVGEGEGKSKKISKKNAAIAVLEELKKLP 172
V F+ G G SKK++K+NAA +L + +P
Sbjct: 197 RVERFIEIGSGTSKKLAKRNAAAKMLLRVHTVP 229
Score = 40.0 bits (92), Expect = 0.005
Identities = 27/69 (39%), Positives = 34/69 (49%), Gaps = 1/69 (1%)
Query: 203 GINPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRN 262
G PIS L Q + K P Y LL G + F +V VG+ + G G +KK AK
Sbjct: 28 GKTPIS-LLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTVGDTSCTGQGPSKKAAKHK 86
Query: 263 AAENMLEIL 271
AAE L+ L
Sbjct: 87 AAEVALKHL 95
>gi|85068512 TAR RNA binding protein 2 isoform b [Homo sapiens]
Length = 345
Score = 78.6 bits (192), Expect = 1e-14
Identities = 58/198 (29%), Positives = 90/198 (45%), Gaps = 29/198 (14%)
Query: 99 NLNKSEISQVFEIALKRNLPVNFEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKK 158
N K+ IS + E + +++ + G H NF +V+VG+ G+G SKK +K
Sbjct: 5 NPGKTPISLLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTVGDTSCTGQGPSKKAAKH 64
Query: 159 NAAIAVLEELK------------------------KLPPLPAVERVKPR---IKKKTKPI 191
AA L+ LK +P A P + ++ P+
Sbjct: 65 KAAEVALKHLKGGSMLEPALEDSSSFSPLDSSLPEDIPVFTAAAAATPVPSVVLTRSPPM 124
Query: 192 -VKPQTSPEYGQGINPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAE 250
++P SP+ + NP+ L ++ K + PEYT+ E G R+EF M +V
Sbjct: 125 ELQPPVSPQQSE-CNPVGALQELVVQKGWRLPEYTVTQESGPAHRKEFTMTCRVERFIEI 183
Query: 251 GTGTNKKVAKRNAAENML 268
G+GT+KK+AKRNAA ML
Sbjct: 184 GSGTSKKLAKRNAAAKML 201
Score = 49.7 bits (117), Expect = 6e-06
Identities = 52/213 (24%), Positives = 87/213 (40%), Gaps = 55/213 (25%)
Query: 4 GKKPMYKPVDPYSRMQSTYNYNM---RGGAYPPRYFYPFPVPPLLYQVELSVGGQQFNGK 60
GK P+ + +R+ T Y++ G A+ P + + ++VG G+
Sbjct: 7 GKTPISLLQEYGTRIGKTPVYDLLKAEGQAHQPNFTF-----------RVTVGDTSCTGQ 55
Query: 61 GKTRQAAKHDAAAKALRILQNEPLPE-RLEVNGRESEEENLNKSEI---------SQVFE 110
G +++AAKH AA AL+ L+ + E LE + S ++ +I + V
Sbjct: 56 GPSKKAAKHKAAEVALKHLKGGSMLEPALEDSSSFSPLDSSLPEDIPVFTAAAAATPVPS 115
Query: 111 IALKRNLPVNFE-------------------------------VARESGPPHMKNFVTKV 139
+ L R+ P+ + V +ESGP H K F
Sbjct: 116 VVLTRSPPMELQPPVSPQQSECNPVGALQELVVQKGWRLPEYTVTQESGPAHRKEFTMTC 175
Query: 140 SVGEFVGEGEGKSKKISKKNAAIAVLEELKKLP 172
V F+ G G SKK++K+NAA +L + +P
Sbjct: 176 RVERFIEIGSGTSKKLAKRNAAAKMLLRVHTVP 208
Score = 40.0 bits (92), Expect = 0.005
Identities = 27/69 (39%), Positives = 34/69 (49%), Gaps = 1/69 (1%)
Query: 203 GINPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRN 262
G PIS L Q + K P Y LL G + F +V VG+ + G G +KK AK
Sbjct: 7 GKTPIS-LLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTVGDTSCTGQGPSKKAAKHK 65
Query: 263 AAENMLEIL 271
AAE L+ L
Sbjct: 66 AAEVALKHL 74
>gi|213417919 protein kinase, interferon-inducible double stranded
RNA dependent activator isoform 3 [Homo sapiens]
Length = 288
Score = 73.9 bits (180), Expect = 3e-13
Identities = 54/168 (32%), Positives = 79/168 (47%), Gaps = 12/168 (7%)
Query: 102 KSEISQVFEIALK-RNLPVNFEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNA 160
K+ I + E +K +N+PV +E R H+ F +V+VG+ GEG SKK++K A
Sbjct: 8 KTPIQVLHEYGMKTKNIPV-YECERSDVQIHVPTFTFRVTVGDITCTGEGTSKKLAKHRA 66
Query: 161 AIAVLEELKKLPPLPAVERVKPRIKKKTKPIVKPQTSPEYGQGINPISRLAQIQQAKKEK 220
A A + LK I + P S + +NPI L ++ +
Sbjct: 67 AEAAINILK----------ANASICFAVPDPLMPDPSKQPKNQLNPIGSLQELAIHHGWR 116
Query: 221 EPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNAAENML 268
PEYTL E G +RE+ ++ + G G +KK AKRNAAE L
Sbjct: 117 LPEYTLSQEGGPAHKREYTTICRLESFMETGKGASKKQAKRNAAEKFL 164
Score = 55.5 bits (132), Expect = 1e-07
Identities = 40/138 (28%), Positives = 67/138 (48%), Gaps = 8/138 (5%)
Query: 41 VPPLLYQVELSVGGQQFNGKGKTRQAAKHDAAAKALRILQNEP-----LPERLEVNGRES 95
VP ++V +VG G+G +++ AKH AA A+ IL+ +P+ L + +
Sbjct: 38 VPTFTFRV--TVGDITCTGEGTSKKLAKHRAAEAAINILKANASICFAVPDPLMPDPSKQ 95
Query: 96 EEENLNKSEISQVFEIALKRNLPVNFEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKI 155
+ LN Q I LP + +++E GP H + + T + F+ G+G SKK
Sbjct: 96 PKNQLNPIGSLQELAIHHGWRLP-EYTLSQEGGPAHKREYTTICRLESFMETGKGASKKQ 154
Query: 156 SKKNAAIAVLEELKKLPP 173
+K+NAA L + + P
Sbjct: 155 AKRNAAEKFLAKFSNISP 172
Score = 42.7 bits (99), Expect = 8e-04
Identities = 60/249 (24%), Positives = 97/249 (38%), Gaps = 22/249 (8%)
Query: 238 FVMQVKVGNHTAEGTGTNKKVAKRNAAENMLEILG------FKVPQAQPTKPALKSEEKT 291
F +V VG+ T G GT+KK+AK AAE + IL F VP P P + K
Sbjct: 41 FTFRVTVGDITCTGEGTSKKLAKHRAAEAAINILKANASICFAVP--DPLMPDPSKQPKN 98
Query: 292 PIKKPGDGRKVTFF------EPGSGDENGTSNKEDEFRMPYL-SHQQLPAGILPMVPEVA 344
+ G +++ E E G ++K + + L S + G
Sbjct: 99 QLNPIGSLQELAIHHGWRLPEYTLSQEGGPAHKREYTTICRLESFMETGKG-----ASKK 153
Query: 345 QAVGVSQGHHTKDFTRAAPNPAKATVTAMIARELLYGGTSPTAETILKNNISSGHVPHGP 404
QA + F+ +P ++T ++ L S K N+ + P
Sbjct: 154 QAKRNAAEKFLAKFSNISPE-NHISLTNVVGHSLGCTWHSLRNSPGEKINLLKRSLLSIP 212
Query: 405 LTRPSEQLDYLSRVQGFQVEYKDFPKNNKN-EFVSLINCSSQPPLISHGIGKDVESCHDM 463
T + L +++ QGF + Y D + + N ++ L S+ P + HG G +
Sbjct: 213 NTDYIQLLSEIAKEQGFNITYLDIDELSANGQYQCLAELSTSPITVCHGSGISCGNAQSD 272
Query: 464 AALNILKLL 472
AA N L+ L
Sbjct: 273 AAHNALQYL 281
>gi|213417911 protein kinase, interferon-inducible double stranded
RNA dependent activator isoform 2 [Homo sapiens]
Length = 302
Score = 73.9 bits (180), Expect = 3e-13
Identities = 54/168 (32%), Positives = 79/168 (47%), Gaps = 12/168 (7%)
Query: 102 KSEISQVFEIALK-RNLPVNFEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNA 160
K+ I + E +K +N+PV +E R H+ F +V+VG+ GEG SKK++K A
Sbjct: 22 KTPIQVLHEYGMKTKNIPV-YECERSDVQIHVPTFTFRVTVGDITCTGEGTSKKLAKHRA 80
Query: 161 AIAVLEELKKLPPLPAVERVKPRIKKKTKPIVKPQTSPEYGQGINPISRLAQIQQAKKEK 220
A A + LK I + P S + +NPI L ++ +
Sbjct: 81 AEAAINILK----------ANASICFAVPDPLMPDPSKQPKNQLNPIGSLQELAIHHGWR 130
Query: 221 EPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNAAENML 268
PEYTL E G +RE+ ++ + G G +KK AKRNAAE L
Sbjct: 131 LPEYTLSQEGGPAHKREYTTICRLESFMETGKGASKKQAKRNAAEKFL 178
Score = 55.8 bits (133), Expect = 9e-08
Identities = 50/180 (27%), Positives = 81/180 (45%), Gaps = 14/180 (7%)
Query: 3 LGKKPMYKPVDPYSRMQSTYNYNMRGGAYP----PRYFYPFPVPPLLYQVELSVGGQQFN 58
LGK KP + +Q + Y M+ P R VP ++V +VG
Sbjct: 12 LGKMITAKPGK--TPIQVLHEYGMKTKNIPVYECERSDVQIHVPTFTFRV--TVGDITCT 67
Query: 59 GKGKTRQAAKHDAAAKALRILQNEP-----LPERLEVNGRESEEENLNKSEISQVFEIAL 113
G+G +++ AKH AA A+ IL+ +P+ L + + + LN Q I
Sbjct: 68 GEGTSKKLAKHRAAEAAINILKANASICFAVPDPLMPDPSKQPKNQLNPIGSLQELAIHH 127
Query: 114 KRNLPVNFEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLPP 173
LP + +++E GP H + + T + F+ G+G SKK +K+NAA L + + P
Sbjct: 128 GWRLP-EYTLSQEGGPAHKREYTTICRLESFMETGKGASKKQAKRNAAEKFLAKFSNISP 186
Score = 42.7 bits (99), Expect = 8e-04
Identities = 60/249 (24%), Positives = 97/249 (38%), Gaps = 22/249 (8%)
Query: 238 FVMQVKVGNHTAEGTGTNKKVAKRNAAENMLEILG------FKVPQAQPTKPALKSEEKT 291
F +V VG+ T G GT+KK+AK AAE + IL F VP P P + K
Sbjct: 55 FTFRVTVGDITCTGEGTSKKLAKHRAAEAAINILKANASICFAVP--DPLMPDPSKQPKN 112
Query: 292 PIKKPGDGRKVTFF------EPGSGDENGTSNKEDEFRMPYL-SHQQLPAGILPMVPEVA 344
+ G +++ E E G ++K + + L S + G
Sbjct: 113 QLNPIGSLQELAIHHGWRLPEYTLSQEGGPAHKREYTTICRLESFMETGKG-----ASKK 167
Query: 345 QAVGVSQGHHTKDFTRAAPNPAKATVTAMIARELLYGGTSPTAETILKNNISSGHVPHGP 404
QA + F+ +P ++T ++ L S K N+ + P
Sbjct: 168 QAKRNAAEKFLAKFSNISPE-NHISLTNVVGHSLGCTWHSLRNSPGEKINLLKRSLLSIP 226
Query: 405 LTRPSEQLDYLSRVQGFQVEYKDFPKNNKN-EFVSLINCSSQPPLISHGIGKDVESCHDM 463
T + L +++ QGF + Y D + + N ++ L S+ P + HG G +
Sbjct: 227 NTDYIQLLSEIAKEQGFNITYLDIDELSANGQYQCLAELSTSPITVCHGSGISCGNAQSD 286
Query: 464 AALNILKLL 472
AA N L+ L
Sbjct: 287 AAHNALQYL 295
>gi|4505581 protein kinase, interferon-inducible double stranded RNA
dependent activator isoform 1 [Homo sapiens]
Length = 313
Score = 73.9 bits (180), Expect = 3e-13
Identities = 54/168 (32%), Positives = 79/168 (47%), Gaps = 12/168 (7%)
Query: 102 KSEISQVFEIALK-RNLPVNFEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNA 160
K+ I + E +K +N+PV +E R H+ F +V+VG+ GEG SKK++K A
Sbjct: 33 KTPIQVLHEYGMKTKNIPV-YECERSDVQIHVPTFTFRVTVGDITCTGEGTSKKLAKHRA 91
Query: 161 AIAVLEELKKLPPLPAVERVKPRIKKKTKPIVKPQTSPEYGQGINPISRLAQIQQAKKEK 220
A A + LK I + P S + +NPI L ++ +
Sbjct: 92 AEAAINILK----------ANASICFAVPDPLMPDPSKQPKNQLNPIGSLQELAIHHGWR 141
Query: 221 EPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNAAENML 268
PEYTL E G +RE+ ++ + G G +KK AKRNAAE L
Sbjct: 142 LPEYTLSQEGGPAHKREYTTICRLESFMETGKGASKKQAKRNAAEKFL 189
Score = 55.8 bits (133), Expect = 9e-08
Identities = 50/180 (27%), Positives = 81/180 (45%), Gaps = 14/180 (7%)
Query: 3 LGKKPMYKPVDPYSRMQSTYNYNMRGGAYP----PRYFYPFPVPPLLYQVELSVGGQQFN 58
LGK KP + +Q + Y M+ P R VP ++V +VG
Sbjct: 23 LGKMITAKPGK--TPIQVLHEYGMKTKNIPVYECERSDVQIHVPTFTFRV--TVGDITCT 78
Query: 59 GKGKTRQAAKHDAAAKALRILQNEP-----LPERLEVNGRESEEENLNKSEISQVFEIAL 113
G+G +++ AKH AA A+ IL+ +P+ L + + + LN Q I
Sbjct: 79 GEGTSKKLAKHRAAEAAINILKANASICFAVPDPLMPDPSKQPKNQLNPIGSLQELAIHH 138
Query: 114 KRNLPVNFEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLPP 173
LP + +++E GP H + + T + F+ G+G SKK +K+NAA L + + P
Sbjct: 139 GWRLP-EYTLSQEGGPAHKREYTTICRLESFMETGKGASKKQAKRNAAEKFLAKFSNISP 197
Score = 42.7 bits (99), Expect = 8e-04
Identities = 60/249 (24%), Positives = 97/249 (38%), Gaps = 22/249 (8%)
Query: 238 FVMQVKVGNHTAEGTGTNKKVAKRNAAENMLEILG------FKVPQAQPTKPALKSEEKT 291
F +V VG+ T G GT+KK+AK AAE + IL F VP P P + K
Sbjct: 66 FTFRVTVGDITCTGEGTSKKLAKHRAAEAAINILKANASICFAVP--DPLMPDPSKQPKN 123
Query: 292 PIKKPGDGRKVTFF------EPGSGDENGTSNKEDEFRMPYL-SHQQLPAGILPMVPEVA 344
+ G +++ E E G ++K + + L S + G
Sbjct: 124 QLNPIGSLQELAIHHGWRLPEYTLSQEGGPAHKREYTTICRLESFMETGKG-----ASKK 178
Query: 345 QAVGVSQGHHTKDFTRAAPNPAKATVTAMIARELLYGGTSPTAETILKNNISSGHVPHGP 404
QA + F+ +P ++T ++ L S K N+ + P
Sbjct: 179 QAKRNAAEKFLAKFSNISPE-NHISLTNVVGHSLGCTWHSLRNSPGEKINLLKRSLLSIP 237
Query: 405 LTRPSEQLDYLSRVQGFQVEYKDFPKNNKN-EFVSLINCSSQPPLISHGIGKDVESCHDM 463
T + L +++ QGF + Y D + + N ++ L S+ P + HG G +
Sbjct: 238 NTDYIQLLSEIAKEQGFNITYLDIDELSANGQYQCLAELSTSPITVCHGSGISCGNAQSD 297
Query: 464 AALNILKLL 472
AA N L+ L
Sbjct: 298 AAHNALQYL 306
>gi|24234756 interleukin enhancer binding factor 3 isoform c [Homo
sapiens]
Length = 690
Score = 60.5 bits (145), Expect = 3e-09
Identities = 59/232 (25%), Positives = 96/232 (41%), Gaps = 41/232 (17%)
Query: 83 PLPERLEVNGRESE--------EENLNKSEISQVFEIALKRNL---PVNFEVARESGPPH 131
P+ +E +G E ++ K+E Q ++ N + +++ ++GP H
Sbjct: 369 PMKRPMEEDGEEKSPSKKKKKIQKKEEKAEPPQAMNALMRLNQLKPGLQYKLVSQTGPVH 428
Query: 132 MKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEEL------------------KKLPP 173
F V V E G SKK +K + A+ VL+++ ++
Sbjct: 429 APIFTMSVEVDGNSFEASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSKGEDSAEETEA 488
Query: 174 LPAVERVKPRIKKKTKPIVK--PQTSPEYG-----QGINPISRLAQIQQAKKEKEPEYTL 226
PAV P ++ + P + E G G NP+ L + K + +Y L
Sbjct: 489 KPAVVAPAPVVEAVSTPSAAFPSDATAEQGPILTKHGKNPVMELNE-----KRRGLKYEL 543
Query: 227 LTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNAAENMLEILGFKVPQA 278
++E G + FVM+V+V +G G+NKKVAK AA LE L P A
Sbjct: 544 ISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAALEKLFPDTPLA 595
Score = 51.2 bits (121), Expect = 2e-06
Identities = 55/206 (26%), Positives = 82/206 (39%), Gaps = 47/206 (22%)
Query: 40 PVPPLLYQVELSVGGQQFNGKGKTRQAAKHDAAAKALRILQNEPLPERLE----VNGRES 95
PV ++ + + V G F G +++ AK A K +LQ+ LP E G +S
Sbjct: 426 PVHAPIFTMSVEVDGNSFEASGPSKKTAKLHVAVK---VLQDMGLPTGAEGRDSSKGEDS 482
Query: 96 EEEN----------------------------------LNKSEISQVFEIALKRNLPVNF 121
EE L K + V E+ KR + +
Sbjct: 483 AEETEAKPAVVAPAPVVEAVSTPSAAFPSDATAEQGPILTKHGKNPVMELNEKRR-GLKY 541
Query: 122 EVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLPPLPAVERVK 181
E+ E+G H K FV +V V +G G +KK++K AA+A LE+L PL K
Sbjct: 542 ELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAALEKLFPDTPLALDANKK 601
Query: 182 PR----IKKKTKPIVKPQTSPEYGQG 203
R ++ K KP +P +G G
Sbjct: 602 KRAPVPVRGGPKFAAKPH-NPGFGMG 626
>gi|24234753 interleukin enhancer binding factor 3 isoform b [Homo
sapiens]
Length = 702
Score = 60.5 bits (145), Expect = 3e-09
Identities = 59/232 (25%), Positives = 96/232 (41%), Gaps = 41/232 (17%)
Query: 83 PLPERLEVNGRESE--------EENLNKSEISQVFEIALKRNL---PVNFEVARESGPPH 131
P+ +E +G E ++ K+E Q ++ N + +++ ++GP H
Sbjct: 369 PMKRPMEEDGEEKSPSKKKKKIQKKEEKAEPPQAMNALMRLNQLKPGLQYKLVSQTGPVH 428
Query: 132 MKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEEL------------------KKLPP 173
F V V E G SKK +K + A+ VL+++ ++
Sbjct: 429 APIFTMSVEVDGNSFEASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSKGEDSAEETEA 488
Query: 174 LPAVERVKPRIKKKTKPIVK--PQTSPEYG-----QGINPISRLAQIQQAKKEKEPEYTL 226
PAV P ++ + P + E G G NP+ L + K + +Y L
Sbjct: 489 KPAVVAPAPVVEAVSTPSAAFPSDATAEQGPILTKHGKNPVMELNE-----KRRGLKYEL 543
Query: 227 LTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNAAENMLEILGFKVPQA 278
++E G + FVM+V+V +G G+NKKVAK AA LE L P A
Sbjct: 544 ISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAALEKLFPDTPLA 595
Score = 51.2 bits (121), Expect = 2e-06
Identities = 55/206 (26%), Positives = 82/206 (39%), Gaps = 47/206 (22%)
Query: 40 PVPPLLYQVELSVGGQQFNGKGKTRQAAKHDAAAKALRILQNEPLPERLE----VNGRES 95
PV ++ + + V G F G +++ AK A K +LQ+ LP E G +S
Sbjct: 426 PVHAPIFTMSVEVDGNSFEASGPSKKTAKLHVAVK---VLQDMGLPTGAEGRDSSKGEDS 482
Query: 96 EEEN----------------------------------LNKSEISQVFEIALKRNLPVNF 121
EE L K + V E+ KR + +
Sbjct: 483 AEETEAKPAVVAPAPVVEAVSTPSAAFPSDATAEQGPILTKHGKNPVMELNEKRR-GLKY 541
Query: 122 EVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLPPLPAVERVK 181
E+ E+G H K FV +V V +G G +KK++K AA+A LE+L PL K
Sbjct: 542 ELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAALEKLFPDTPLALDANKK 601
Query: 182 PR----IKKKTKPIVKPQTSPEYGQG 203
R ++ K KP +P +G G
Sbjct: 602 KRAPVPVRGGPKFAAKPH-NPGFGMG 626
>gi|24234750 interleukin enhancer binding factor 3 isoform a [Homo
sapiens]
Length = 894
Score = 60.5 bits (145), Expect = 3e-09
Identities = 59/232 (25%), Positives = 96/232 (41%), Gaps = 41/232 (17%)
Query: 83 PLPERLEVNGRESE--------EENLNKSEISQVFEIALKRNL---PVNFEVARESGPPH 131
P+ +E +G E ++ K+E Q ++ N + +++ ++GP H
Sbjct: 369 PMKRPMEEDGEEKSPSKKKKKIQKKEEKAEPPQAMNALMRLNQLKPGLQYKLVSQTGPVH 428
Query: 132 MKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEEL------------------KKLPP 173
F V V E G SKK +K + A+ VL+++ ++
Sbjct: 429 APIFTMSVEVDGNSFEASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSKGEDSAEETEA 488
Query: 174 LPAVERVKPRIKKKTKPIVK--PQTSPEYG-----QGINPISRLAQIQQAKKEKEPEYTL 226
PAV P ++ + P + E G G NP+ L + K + +Y L
Sbjct: 489 KPAVVAPAPVVEAVSTPSAAFPSDATAEQGPILTKHGKNPVMELNE-----KRRGLKYEL 543
Query: 227 LTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNAAENMLEILGFKVPQA 278
++E G + FVM+V+V +G G+NKKVAK AA LE L P A
Sbjct: 544 ISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAALEKLFPDTPLA 595
Score = 51.2 bits (121), Expect = 2e-06
Identities = 55/206 (26%), Positives = 82/206 (39%), Gaps = 47/206 (22%)
Query: 40 PVPPLLYQVELSVGGQQFNGKGKTRQAAKHDAAAKALRILQNEPLPERLE----VNGRES 95
PV ++ + + V G F G +++ AK A K +LQ+ LP E G +S
Sbjct: 426 PVHAPIFTMSVEVDGNSFEASGPSKKTAKLHVAVK---VLQDMGLPTGAEGRDSSKGEDS 482
Query: 96 EEEN----------------------------------LNKSEISQVFEIALKRNLPVNF 121
EE L K + V E+ KR + +
Sbjct: 483 AEETEAKPAVVAPAPVVEAVSTPSAAFPSDATAEQGPILTKHGKNPVMELNEKRR-GLKY 541
Query: 122 EVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLPPLPAVERVK 181
E+ E+G H K FV +V V +G G +KK++K AA+A LE+L PL K
Sbjct: 542 ELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAALEKLFPDTPLALDANKK 601
Query: 182 PR----IKKKTKPIVKPQTSPEYGQG 203
R ++ K KP +P +G G
Sbjct: 602 KRAPVPVRGGPKFAAKPH-NPGFGMG 626
>gi|212549555 interleukin enhancer binding factor 3 isoform e [Homo
sapiens]
Length = 706
Score = 60.1 bits (144), Expect = 5e-09
Identities = 60/236 (25%), Positives = 96/236 (40%), Gaps = 45/236 (19%)
Query: 83 PLPERLEVNGRESE--------EENLNKSEISQVFEIALKRNL---PVNFEVARESGPPH 131
P+ +E +G E ++ K+E Q ++ N + +++ ++GP H
Sbjct: 369 PMKRPMEEDGEEKSPSKKKKKIQKKEEKAEPPQAMNALMRLNQLKPGLQYKLVSQTGPVH 428
Query: 132 MKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEEL------------------KKLPP 173
F V V E G SKK +K + A+ VL+++ ++
Sbjct: 429 APIFTMSVEVDGNSFEASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSKGEDSAEETEA 488
Query: 174 LPAVERVKPRIKKKTKPI-----------VKPQTSPEYGQGINPISRLAQIQQAKKEKEP 222
PAV P ++ + P VK Q G NP+ L + K +
Sbjct: 489 KPAVVAPAPVVEAVSTPSAAFPSDATAENVKQQGPILTKHGKNPVMELNE-----KRRGL 543
Query: 223 EYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNAAENMLEILGFKVPQA 278
+Y L++E G + FVM+V+V +G G+NKKVAK AA LE L P A
Sbjct: 544 KYELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAALEKLFPDTPLA 599
Score = 49.7 bits (117), Expect = 6e-06
Identities = 55/210 (26%), Positives = 82/210 (39%), Gaps = 51/210 (24%)
Query: 40 PVPPLLYQVELSVGGQQFNGKGKTRQAAKHDAAAKALRILQNEPLPERLE----VNGRES 95
PV ++ + + V G F G +++ AK A K +LQ+ LP E G +S
Sbjct: 426 PVHAPIFTMSVEVDGNSFEASGPSKKTAKLHVAVK---VLQDMGLPTGAEGRDSSKGEDS 482
Query: 96 EEEN--------------------------------------LNKSEISQVFEIALKRNL 117
EE L K + V E+ KR
Sbjct: 483 AEETEAKPAVVAPAPVVEAVSTPSAAFPSDATAENVKQQGPILTKHGKNPVMELNEKRR- 541
Query: 118 PVNFEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLPPLPAV 177
+ +E+ E+G H K FV +V V +G G +KK++K AA+A LE+L PL
Sbjct: 542 GLKYELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAALEKLFPDTPLALD 601
Query: 178 ERVKPR----IKKKTKPIVKPQTSPEYGQG 203
K R ++ K KP +P +G G
Sbjct: 602 ANKKKRAPVPVRGGPKFAAKPH-NPGFGMG 630
>gi|212549553 interleukin enhancer binding factor 3 isoform d [Homo
sapiens]
Length = 898
Score = 60.1 bits (144), Expect = 5e-09
Identities = 60/236 (25%), Positives = 96/236 (40%), Gaps = 45/236 (19%)
Query: 83 PLPERLEVNGRESE--------EENLNKSEISQVFEIALKRNL---PVNFEVARESGPPH 131
P+ +E +G E ++ K+E Q ++ N + +++ ++GP H
Sbjct: 369 PMKRPMEEDGEEKSPSKKKKKIQKKEEKAEPPQAMNALMRLNQLKPGLQYKLVSQTGPVH 428
Query: 132 MKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEEL------------------KKLPP 173
F V V E G SKK +K + A+ VL+++ ++
Sbjct: 429 APIFTMSVEVDGNSFEASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSKGEDSAEETEA 488
Query: 174 LPAVERVKPRIKKKTKPI-----------VKPQTSPEYGQGINPISRLAQIQQAKKEKEP 222
PAV P ++ + P VK Q G NP+ L + K +
Sbjct: 489 KPAVVAPAPVVEAVSTPSAAFPSDATAENVKQQGPILTKHGKNPVMELNE-----KRRGL 543
Query: 223 EYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNAAENMLEILGFKVPQA 278
+Y L++E G + FVM+V+V +G G+NKKVAK AA LE L P A
Sbjct: 544 KYELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAALEKLFPDTPLA 599
Score = 49.7 bits (117), Expect = 6e-06
Identities = 55/210 (26%), Positives = 82/210 (39%), Gaps = 51/210 (24%)
Query: 40 PVPPLLYQVELSVGGQQFNGKGKTRQAAKHDAAAKALRILQNEPLPERLE----VNGRES 95
PV ++ + + V G F G +++ AK A K +LQ+ LP E G +S
Sbjct: 426 PVHAPIFTMSVEVDGNSFEASGPSKKTAKLHVAVK---VLQDMGLPTGAEGRDSSKGEDS 482
Query: 96 EEEN--------------------------------------LNKSEISQVFEIALKRNL 117
EE L K + V E+ KR
Sbjct: 483 AEETEAKPAVVAPAPVVEAVSTPSAAFPSDATAENVKQQGPILTKHGKNPVMELNEKRR- 541
Query: 118 PVNFEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLPPLPAV 177
+ +E+ E+G H K FV +V V +G G +KK++K AA+A LE+L PL
Sbjct: 542 GLKYELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAALEKLFPDTPLALD 601
Query: 178 ERVKPR----IKKKTKPIVKPQTSPEYGQG 203
K R ++ K KP +P +G G
Sbjct: 602 ANKKKRAPVPVRGGPKFAAKPH-NPGFGMG 630
>gi|237681091 RNA-specific adenosine deaminase B1 isoform 7 [Homo
sapiens]
Length = 674
Score = 59.7 bits (143), Expect = 6e-09
Identities = 71/254 (27%), Positives = 102/254 (40%), Gaps = 48/254 (18%)
Query: 40 PVPPLLYQVELSVGGQQFNGKGKTRQAAKHDAAAKALRILQNEPLPERLEVNGRESEEEN 99
PV L+ + + V GQ F G G T++ AK AA KALR P
Sbjct: 103 PVHAPLFVMSVEVNGQVFEGSGPTKKKAKLHAAEKALRSFVQFP---------------- 146
Query: 100 LNKSEISQVFEIALKRNLPVNFEVARESG--PPHMKN-FVT--KVSVGEFVGEGEGKSKK 154
N SE +A+ R L VN + + P + N F T K +VG S
Sbjct: 147 -NASEA----HLAMGRTLSVNTDFTSDQADFPDTLFNGFETPDKAEPPFYVGSNGDDSFS 201
Query: 155 ISKKNAAIAVLEELKKLPPLPAVERVKPRIKKKTKPIVKPQTSPEYGQGINPISRLAQIQ 214
S + A P+PA + + P++ P P G NP+ L +++
Sbjct: 202 SSGDLSLSA--------SPVPA------SLAQPPLPVLPPFPPP---SGKNPVMILNELR 244
Query: 215 QAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNAAENMLEILGFK 274
K Y L+E G + FVM V V EG+G NKK+AK AA++ L +
Sbjct: 245 PGLK-----YDFLSESGESHAKSFVMSVVVDGQFFEGSGRNKKLAKARAAQSALAAIFNL 299
Query: 275 VPQAQPTKPALKSE 288
P++ + SE
Sbjct: 300 HLDQTPSRQPIPSE 313
Score = 40.0 bits (92), Expect = 0.005
Identities = 25/63 (39%), Positives = 34/63 (53%), Gaps = 2/63 (3%)
Query: 206 PISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNAAE 265
P + L Q+ + K + YTLL++ G FVM V+V EG+G KK AK +AAE
Sbjct: 79 PKNALMQLNEIKPGLQ--YTLLSQTGPVHAPLFVMSVEVNGQVFEGSGPTKKKAKLHAAE 136
Query: 266 NML 268
L
Sbjct: 137 KAL 139
Score = 33.5 bits (75), Expect = 0.46
Identities = 18/54 (33%), Positives = 27/54 (50%)
Query: 119 VNFEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLP 172
+ + + ++GP H FV V V V EG G +KK +K +AA L + P
Sbjct: 93 LQYTLLSQTGPVHAPLFVMSVEVNGQVFEGSGPTKKKAKLHAAEKALRSFVQFP 146
>gi|7669479 RNA-specific adenosine deaminase B1 isoform 3 [Homo
sapiens]
Length = 714
Score = 59.7 bits (143), Expect = 6e-09
Identities = 71/254 (27%), Positives = 102/254 (40%), Gaps = 48/254 (18%)
Query: 40 PVPPLLYQVELSVGGQQFNGKGKTRQAAKHDAAAKALRILQNEPLPERLEVNGRESEEEN 99
PV L+ + + V GQ F G G T++ AK AA KALR P
Sbjct: 103 PVHAPLFVMSVEVNGQVFEGSGPTKKKAKLHAAEKALRSFVQFP---------------- 146
Query: 100 LNKSEISQVFEIALKRNLPVNFEVARESG--PPHMKN-FVT--KVSVGEFVGEGEGKSKK 154
N SE +A+ R L VN + + P + N F T K +VG S
Sbjct: 147 -NASEA----HLAMGRTLSVNTDFTSDQADFPDTLFNGFETPDKAEPPFYVGSNGDDSFS 201
Query: 155 ISKKNAAIAVLEELKKLPPLPAVERVKPRIKKKTKPIVKPQTSPEYGQGINPISRLAQIQ 214
S + A P+PA + + P++ P P G NP+ L +++
Sbjct: 202 SSGDLSLSA--------SPVPA------SLAQPPLPVLPPFPPP---SGKNPVMILNELR 244
Query: 215 QAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNAAENMLEILGFK 274
K Y L+E G + FVM V V EG+G NKK+AK AA++ L +
Sbjct: 245 PGLK-----YDFLSESGESHAKSFVMSVVVDGQFFEGSGRNKKLAKARAAQSALAAIFNL 299
Query: 275 VPQAQPTKPALKSE 288
P++ + SE
Sbjct: 300 HLDQTPSRQPIPSE 313
Score = 40.0 bits (92), Expect = 0.005
Identities = 25/63 (39%), Positives = 34/63 (53%), Gaps = 2/63 (3%)
Query: 206 PISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNAAE 265
P + L Q+ + K + YTLL++ G FVM V+V EG+G KK AK +AAE
Sbjct: 79 PKNALMQLNEIKPGLQ--YTLLSQTGPVHAPLFVMSVEVNGQVFEGSGPTKKKAKLHAAE 136
Query: 266 NML 268
L
Sbjct: 137 KAL 139
Score = 33.5 bits (75), Expect = 0.46
Identities = 18/54 (33%), Positives = 27/54 (50%)
Query: 119 VNFEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLP 172
+ + + ++GP H FV V V V EG G +KK +K +AA L + P
Sbjct: 93 LQYTLLSQTGPVHAPLFVMSVEVNGQVFEGSGPTKKKAKLHAAEKALRSFVQFP 146
>gi|7669477 RNA-specific adenosine deaminase B1 isoform 2 [Homo
sapiens]
Length = 741
Score = 59.7 bits (143), Expect = 6e-09
Identities = 71/254 (27%), Positives = 102/254 (40%), Gaps = 48/254 (18%)
Query: 40 PVPPLLYQVELSVGGQQFNGKGKTRQAAKHDAAAKALRILQNEPLPERLEVNGRESEEEN 99
PV L+ + + V GQ F G G T++ AK AA KALR P
Sbjct: 103 PVHAPLFVMSVEVNGQVFEGSGPTKKKAKLHAAEKALRSFVQFP---------------- 146
Query: 100 LNKSEISQVFEIALKRNLPVNFEVARESG--PPHMKN-FVT--KVSVGEFVGEGEGKSKK 154
N SE +A+ R L VN + + P + N F T K +VG S
Sbjct: 147 -NASEA----HLAMGRTLSVNTDFTSDQADFPDTLFNGFETPDKAEPPFYVGSNGDDSFS 201
Query: 155 ISKKNAAIAVLEELKKLPPLPAVERVKPRIKKKTKPIVKPQTSPEYGQGINPISRLAQIQ 214
S + A P+PA + + P++ P P G NP+ L +++
Sbjct: 202 SSGDLSLSA--------SPVPA------SLAQPPLPVLPPFPPP---SGKNPVMILNELR 244
Query: 215 QAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNAAENMLEILGFK 274
K Y L+E G + FVM V V EG+G NKK+AK AA++ L +
Sbjct: 245 PGLK-----YDFLSESGESHAKSFVMSVVVDGQFFEGSGRNKKLAKARAAQSALAAIFNL 299
Query: 275 VPQAQPTKPALKSE 288
P++ + SE
Sbjct: 300 HLDQTPSRQPIPSE 313
Score = 40.0 bits (92), Expect = 0.005
Identities = 25/63 (39%), Positives = 34/63 (53%), Gaps = 2/63 (3%)
Query: 206 PISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNAAE 265
P + L Q+ + K + YTLL++ G FVM V+V EG+G KK AK +AAE
Sbjct: 79 PKNALMQLNEIKPGLQ--YTLLSQTGPVHAPLFVMSVEVNGQVFEGSGPTKKKAKLHAAE 136
Query: 266 NML 268
L
Sbjct: 137 KAL 139
Score = 33.5 bits (75), Expect = 0.46
Identities = 18/54 (33%), Positives = 27/54 (50%)
Query: 119 VNFEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLP 172
+ + + ++GP H FV V V V EG G +KK +K +AA L + P
Sbjct: 93 LQYTLLSQTGPVHAPLFVMSVEVNGQVFEGSGPTKKKAKLHAAEKALRSFVQFP 146
>gi|4501919 RNA-specific adenosine deaminase B1 isoform 1 [Homo
sapiens]
Length = 701
Score = 59.7 bits (143), Expect = 6e-09
Identities = 71/254 (27%), Positives = 102/254 (40%), Gaps = 48/254 (18%)
Query: 40 PVPPLLYQVELSVGGQQFNGKGKTRQAAKHDAAAKALRILQNEPLPERLEVNGRESEEEN 99
PV L+ + + V GQ F G G T++ AK AA KALR P
Sbjct: 103 PVHAPLFVMSVEVNGQVFEGSGPTKKKAKLHAAEKALRSFVQFP---------------- 146
Query: 100 LNKSEISQVFEIALKRNLPVNFEVARESG--PPHMKN-FVT--KVSVGEFVGEGEGKSKK 154
N SE +A+ R L VN + + P + N F T K +VG S
Sbjct: 147 -NASEA----HLAMGRTLSVNTDFTSDQADFPDTLFNGFETPDKAEPPFYVGSNGDDSFS 201
Query: 155 ISKKNAAIAVLEELKKLPPLPAVERVKPRIKKKTKPIVKPQTSPEYGQGINPISRLAQIQ 214
S + A P+PA + + P++ P P G NP+ L +++
Sbjct: 202 SSGDLSLSA--------SPVPA------SLAQPPLPVLPPFPPP---SGKNPVMILNELR 244
Query: 215 QAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNAAENMLEILGFK 274
K Y L+E G + FVM V V EG+G NKK+AK AA++ L +
Sbjct: 245 PGLK-----YDFLSESGESHAKSFVMSVVVDGQFFEGSGRNKKLAKARAAQSALAAIFNL 299
Query: 275 VPQAQPTKPALKSE 288
P++ + SE
Sbjct: 300 HLDQTPSRQPIPSE 313
Score = 40.0 bits (92), Expect = 0.005
Identities = 25/63 (39%), Positives = 34/63 (53%), Gaps = 2/63 (3%)
Query: 206 PISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNAAE 265
P + L Q+ + K + YTLL++ G FVM V+V EG+G KK AK +AAE
Sbjct: 79 PKNALMQLNEIKPGLQ--YTLLSQTGPVHAPLFVMSVEVNGQVFEGSGPTKKKAKLHAAE 136
Query: 266 NML 268
L
Sbjct: 137 KAL 139
Score = 33.5 bits (75), Expect = 0.46
Identities = 18/54 (33%), Positives = 27/54 (50%)
Query: 119 VNFEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLP 172
+ + + ++GP H FV V V V EG G +KK +K +AA L + P
Sbjct: 93 LQYTLLSQTGPVHAPLFVMSVEVNGQVFEGSGPTKKKAKLHAAEKALRSFVQFP 146
>gi|70167113 adenosine deaminase, RNA-specific isoform d [Homo
sapiens]
Length = 931
Score = 56.2 bits (134), Expect = 7e-08
Identities = 51/180 (28%), Positives = 85/180 (47%), Gaps = 11/180 (6%)
Query: 102 KSEISQVFEIALKRNLPVNFEVARESGPPHMKNFVTKVSV-GEFVGEGEGKSKKISKKNA 160
K+ IS + E A + F + +SGPPH F +V + G E SKK++K++A
Sbjct: 207 KNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDA 266
Query: 161 AI----AVLEELKKLPPLPAVERVKPRIKKKTKPIVKPQT----SPEYGQGINPISRLAQ 212
A+ +LEE K + E +K+++ + QT + + G +P++ L +
Sbjct: 267 AMKAMTILLEEAKAKDSGKSEESSHYSTEKESEKTAESQTPTPSATSFFSGKSPVTTLLE 326
Query: 213 IQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEG-TGTNKKVAKRNAAENMLEIL 271
K E+ LL++ G +F V VG T + +KKVAK+ AAE ++ L
Sbjct: 327 CMH-KLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKAL 385
Score = 44.7 bits (104), Expect = 2e-04
Identities = 60/266 (22%), Positives = 102/266 (38%), Gaps = 48/266 (18%)
Query: 46 YQVELSVGGQQFN-GKGKTRQAAKHDAAAKALRILQNEPLP------ERLEVNGRESEEE 98
++ ++ + G++F + +++ AK DAA KA+ IL E E E E E
Sbjct: 240 FKFQVVINGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDSGKSEESSHYSTEKESE 299
Query: 99 NL---------------NKSEISQVFEIALKRNLPVNFEVARESGPPHMKNFVTKVSVG- 142
KS ++ + E K F + + GP H F V+VG
Sbjct: 300 KTAESQTPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGA 359
Query: 143 EFVGEGEGKSKKISKKNAAIAVLEELKK----------------LPPLPAVERVKPRIKK 186
+ SKK++K+ AA ++ L L +E + P +
Sbjct: 360 QTFPSVSAPSKKVAKQMAAEEAMKALHGEATNSMASDNQPEGMISESLDNLESMMPNKVR 419
Query: 187 KTKPIVKPQTSPEYGQGINPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGN 246
K +V+ + NP+ L + ++ E+ L+ + G P +FV Q KVG
Sbjct: 420 KIGELVRYLNT-------NPVGGLLEYARSHGFAA-EFKLVDQSGPPHEPKFVYQAKVGG 471
Query: 247 HTAEGT-GTNKKVAKRNAAENMLEIL 271
+KK K+ AA+ L +L
Sbjct: 472 RWFPAVCAHSKKQGKQEAADAALRVL 497
Score = 39.7 bits (91), Expect = 0.006
Identities = 46/192 (23%), Positives = 78/192 (40%), Gaps = 38/192 (19%)
Query: 4 GKKPMYKPVDPYSRMQSTYNYNM---RGGAYPPRYFYPFPVPPLLYQVELSVGGQQFNG- 59
GK P+ ++ ++ ++ + + G A+ P++ Y ++VG Q F
Sbjct: 317 GKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYC-----------VAVGAQTFPSV 365
Query: 60 KGKTRQAAKHDAAAKALRILQNEPL--------PERL---EVNGRESEEEN--------- 99
+++ AK AA +A++ L E PE + ++ ES N
Sbjct: 366 SAPSKKVAKQMAAEEAMKALHGEATNSMASDNQPEGMISESLDNLESMMPNKVRKIGELV 425
Query: 100 --LNKSEISQVFEIALKRNLPVNFEVARESGPPHMKNFVTKVSV-GEFVGEGEGKSKKIS 156
LN + + + E A F++ +SGPPH FV + V G + SKK
Sbjct: 426 RYLNTNPVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQG 485
Query: 157 KKNAAIAVLEEL 168
K+ AA A L L
Sbjct: 486 KQEAADAALRVL 497
>gi|70167032 adenosine deaminase, RNA-specific isoform c [Homo
sapiens]
Length = 1181
Score = 56.2 bits (134), Expect = 7e-08
Identities = 51/180 (28%), Positives = 85/180 (47%), Gaps = 11/180 (6%)
Query: 102 KSEISQVFEIALKRNLPVNFEVARESGPPHMKNFVTKVSV-GEFVGEGEGKSKKISKKNA 160
K+ IS + E A + F + +SGPPH F +V + G E SKK++K++A
Sbjct: 502 KNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDA 561
Query: 161 AI----AVLEELKKLPPLPAVERVKPRIKKKTKPIVKPQT----SPEYGQGINPISRLAQ 212
A+ +LEE K + E +K+++ + QT + + G +P++ L +
Sbjct: 562 AMKAMTILLEEAKAKDSGKSEESSHYSTEKESEKTAESQTPTPSATSFFSGKSPVTTLLE 621
Query: 213 IQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEG-TGTNKKVAKRNAAENMLEIL 271
K E+ LL++ G +F V VG T + +KKVAK+ AAE ++ L
Sbjct: 622 CMH-KLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKAL 680
Score = 45.8 bits (107), Expect = 9e-05
Identities = 59/250 (23%), Positives = 98/250 (39%), Gaps = 35/250 (14%)
Query: 46 YQVELSVGGQQFN-GKGKTRQAAKHDAAAKALRILQNEPLP------ERLEVNGRESEEE 98
++ ++ + G++F + +++ AK DAA KA+ IL E E E E E
Sbjct: 535 FKFQVVINGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDSGKSEESSHYSTEKESE 594
Query: 99 NL---------------NKSEISQVFEIALKRNLPVNFEVARESGPPHMKNFVTKVSVG- 142
KS ++ + E K F + + GP H F V+VG
Sbjct: 595 KTAESQTPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGA 654
Query: 143 EFVGEGEGKSKKISKKNAAIAVLEELKKLPPLPAVERVKPRIKKKTKPIVKPQTSPEYGQ 202
+ SKK++K+ AA E +K L +K +V+ +
Sbjct: 655 QTFPSVSAPSKKVAKQMAAE---EAMKALHGEATNSMASDNQVRKIGELVRYLNT----- 706
Query: 203 GINPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGT-GTNKKVAKR 261
NP+ L + ++ E+ L+ + G P +FV Q KVG +KK K+
Sbjct: 707 --NPVGGLLEYARSHGFAA-EFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQ 763
Query: 262 NAAENMLEIL 271
AA+ L +L
Sbjct: 764 EAADAALRVL 773
Score = 43.9 bits (102), Expect = 3e-04
Identities = 43/173 (24%), Positives = 72/173 (41%), Gaps = 19/173 (10%)
Query: 4 GKKPMYKPVDPYSRMQSTYNYNM---RGGAYPPRYFYPFPVPPLLYQVELSVGGQQFNG- 59
GK P+ ++ ++ ++ + + G A+ P++ Y ++VG Q F
Sbjct: 612 GKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYC-----------VAVGAQTFPSV 660
Query: 60 KGKTRQAAKHDAAAKALRILQNEPLPERLEVNGRESEEE---NLNKSEISQVFEIALKRN 116
+++ AK AA +A++ L E N E LN + + + E A
Sbjct: 661 SAPSKKVAKQMAAEEAMKALHGEATNSMASDNQVRKIGELVRYLNTNPVGGLLEYARSHG 720
Query: 117 LPVNFEVARESGPPHMKNFVTKVSV-GEFVGEGEGKSKKISKKNAAIAVLEEL 168
F++ +SGPPH FV + V G + SKK K+ AA A L L
Sbjct: 721 FAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVL 773
>gi|70166944 adenosine deaminase, RNA-specific isoform b [Homo
sapiens]
Length = 1200
Score = 56.2 bits (134), Expect = 7e-08
Identities = 51/180 (28%), Positives = 85/180 (47%), Gaps = 11/180 (6%)
Query: 102 KSEISQVFEIALKRNLPVNFEVARESGPPHMKNFVTKVSV-GEFVGEGEGKSKKISKKNA 160
K+ IS + E A + F + +SGPPH F +V + G E SKK++K++A
Sbjct: 502 KNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDA 561
Query: 161 AI----AVLEELKKLPPLPAVERVKPRIKKKTKPIVKPQT----SPEYGQGINPISRLAQ 212
A+ +LEE K + E +K+++ + QT + + G +P++ L +
Sbjct: 562 AMKAMTILLEEAKAKDSGKSEESSHYSTEKESEKTAESQTPTPSATSFFSGKSPVTTLLE 621
Query: 213 IQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEG-TGTNKKVAKRNAAENMLEIL 271
K E+ LL++ G +F V VG T + +KKVAK+ AAE ++ L
Sbjct: 622 CMH-KLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKAL 680
Score = 44.7 bits (104), Expect = 2e-04
Identities = 60/266 (22%), Positives = 102/266 (38%), Gaps = 48/266 (18%)
Query: 46 YQVELSVGGQQFN-GKGKTRQAAKHDAAAKALRILQNEPLP------ERLEVNGRESEEE 98
++ ++ + G++F + +++ AK DAA KA+ IL E E E E E
Sbjct: 535 FKFQVVINGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDSGKSEESSHYSTEKESE 594
Query: 99 NL---------------NKSEISQVFEIALKRNLPVNFEVARESGPPHMKNFVTKVSVG- 142
KS ++ + E K F + + GP H F V+VG
Sbjct: 595 KTAESQTPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGA 654
Query: 143 EFVGEGEGKSKKISKKNAAIAVLEELKK----------------LPPLPAVERVKPRIKK 186
+ SKK++K+ AA ++ L L +E + P +
Sbjct: 655 QTFPSVSAPSKKVAKQMAAEEAMKALHGEATNSMASDNQPEGMISESLDNLESMMPNKVR 714
Query: 187 KTKPIVKPQTSPEYGQGINPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGN 246
K +V+ + NP+ L + ++ E+ L+ + G P +FV Q KVG
Sbjct: 715 KIGELVRYLNT-------NPVGGLLEYARSHGFAA-EFKLVDQSGPPHEPKFVYQAKVGG 766
Query: 247 HTAEGT-GTNKKVAKRNAAENMLEIL 271
+KK K+ AA+ L +L
Sbjct: 767 RWFPAVCAHSKKQGKQEAADAALRVL 792
Score = 39.7 bits (91), Expect = 0.006
Identities = 46/192 (23%), Positives = 78/192 (40%), Gaps = 38/192 (19%)
Query: 4 GKKPMYKPVDPYSRMQSTYNYNM---RGGAYPPRYFYPFPVPPLLYQVELSVGGQQFNG- 59
GK P+ ++ ++ ++ + + G A+ P++ Y ++VG Q F
Sbjct: 612 GKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYC-----------VAVGAQTFPSV 660
Query: 60 KGKTRQAAKHDAAAKALRILQNEPL--------PERL---EVNGRESEEEN--------- 99
+++ AK AA +A++ L E PE + ++ ES N
Sbjct: 661 SAPSKKVAKQMAAEEAMKALHGEATNSMASDNQPEGMISESLDNLESMMPNKVRKIGELV 720
Query: 100 --LNKSEISQVFEIALKRNLPVNFEVARESGPPHMKNFVTKVSV-GEFVGEGEGKSKKIS 156
LN + + + E A F++ +SGPPH FV + V G + SKK
Sbjct: 721 RYLNTNPVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQG 780
Query: 157 KKNAAIAVLEEL 168
K+ AA A L L
Sbjct: 781 KQEAADAALRVL 792
>gi|70166852 adenosine deaminase, RNA-specific isoform a [Homo
sapiens]
Length = 1226
Score = 56.2 bits (134), Expect = 7e-08
Identities = 51/180 (28%), Positives = 85/180 (47%), Gaps = 11/180 (6%)
Query: 102 KSEISQVFEIALKRNLPVNFEVARESGPPHMKNFVTKVSV-GEFVGEGEGKSKKISKKNA 160
K+ IS + E A + F + +SGPPH F +V + G E SKK++K++A
Sbjct: 502 KNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDA 561
Query: 161 AI----AVLEELKKLPPLPAVERVKPRIKKKTKPIVKPQT----SPEYGQGINPISRLAQ 212
A+ +LEE K + E +K+++ + QT + + G +P++ L +
Sbjct: 562 AMKAMTILLEEAKAKDSGKSEESSHYSTEKESEKTAESQTPTPSATSFFSGKSPVTTLLE 621
Query: 213 IQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEG-TGTNKKVAKRNAAENMLEIL 271
K E+ LL++ G +F V VG T + +KKVAK+ AAE ++ L
Sbjct: 622 CMH-KLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKAL 680
Score = 44.7 bits (104), Expect = 2e-04
Identities = 60/266 (22%), Positives = 102/266 (38%), Gaps = 48/266 (18%)
Query: 46 YQVELSVGGQQFN-GKGKTRQAAKHDAAAKALRILQNEPLP------ERLEVNGRESEEE 98
++ ++ + G++F + +++ AK DAA KA+ IL E E E E E
Sbjct: 535 FKFQVVINGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDSGKSEESSHYSTEKESE 594
Query: 99 NL---------------NKSEISQVFEIALKRNLPVNFEVARESGPPHMKNFVTKVSVG- 142
KS ++ + E K F + + GP H F V+VG
Sbjct: 595 KTAESQTPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGA 654
Query: 143 EFVGEGEGKSKKISKKNAAIAVLEELKK----------------LPPLPAVERVKPRIKK 186
+ SKK++K+ AA ++ L L +E + P +
Sbjct: 655 QTFPSVSAPSKKVAKQMAAEEAMKALHGEATNSMASDNQPEGMISESLDNLESMMPNKVR 714
Query: 187 KTKPIVKPQTSPEYGQGINPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGN 246
K +V+ + NP+ L + ++ E+ L+ + G P +FV Q KVG
Sbjct: 715 KIGELVRYLNT-------NPVGGLLEYARSHGFAA-EFKLVDQSGPPHEPKFVYQAKVGG 766
Query: 247 HTAEGT-GTNKKVAKRNAAENMLEIL 271
+KK K+ AA+ L +L
Sbjct: 767 RWFPAVCAHSKKQGKQEAADAALRVL 792
Score = 39.7 bits (91), Expect = 0.006
Identities = 46/192 (23%), Positives = 78/192 (40%), Gaps = 38/192 (19%)
Query: 4 GKKPMYKPVDPYSRMQSTYNYNM---RGGAYPPRYFYPFPVPPLLYQVELSVGGQQFNG- 59
GK P+ ++ ++ ++ + + G A+ P++ Y ++VG Q F
Sbjct: 612 GKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYC-----------VAVGAQTFPSV 660
Query: 60 KGKTRQAAKHDAAAKALRILQNEPL--------PERL---EVNGRESEEEN--------- 99
+++ AK AA +A++ L E PE + ++ ES N
Sbjct: 661 SAPSKKVAKQMAAEEAMKALHGEATNSMASDNQPEGMISESLDNLESMMPNKVRKIGELV 720
Query: 100 --LNKSEISQVFEIALKRNLPVNFEVARESGPPHMKNFVTKVSV-GEFVGEGEGKSKKIS 156
LN + + + E A F++ +SGPPH FV + V G + SKK
Sbjct: 721 RYLNTNPVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQG 780
Query: 157 KKNAAIAVLEEL 168
K+ AA A L L
Sbjct: 781 KQEAADAALRVL 792
>gi|21361745 spermatid perinuclear RNA binding protein [Homo
sapiens]
Length = 672
Score = 55.8 bits (133), Expect = 9e-08
Identities = 50/187 (26%), Positives = 78/187 (41%), Gaps = 27/187 (14%)
Query: 119 VNFEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEEL-------KKL 171
+ +++ +SGP H F V V E G SKK +K + A+ VL+ + +
Sbjct: 402 LQYKLLSQSGPVHAPVFTMSVDVDGTTYEASGPSKKTAKLHVAVKVLQAMGYPTGFDADI 461
Query: 172 PPLPAVERVKPRIKKKTKPIVKPQTSPEYGQGINPISRLAQIQQA--------------- 216
+ + E+ K +T V +S G S +++
Sbjct: 462 ECMSSDEKSDNESKNET---VSSNSSNNTGNSTTETSSTLEVRTQGPILTASGKNPVMEL 518
Query: 217 -KKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNAAENMLEILGFKV 275
+K + +Y L++E G + FVM+V+V G G NKKVAK +AA LE L F
Sbjct: 519 NEKRRGLKYELISETGGSHDKRFVMEVEVDGQKFRGAGPNKKVAKASAALAALEKL-FSG 577
Query: 276 PQAQPTK 282
P A K
Sbjct: 578 PNAANNK 584
Score = 47.4 bits (111), Expect = 3e-05
Identities = 47/193 (24%), Positives = 77/193 (39%), Gaps = 38/193 (19%)
Query: 40 PVPPLLYQVELSVGGQQFNGKGKTRQAAKHDAAAKALRIL-------------------- 79
PV ++ + + V G + G +++ AK A K L+ +
Sbjct: 412 PVHAPVFTMSVDVDGTTYEASGPSKKTAKLHVAVKVLQAMGYPTGFDADIECMSSDEKSD 471
Query: 80 ---QNEPLPERLEVNGRESEEENLNKSEI------------SQVFEIALKRNLPVNFEVA 124
+NE + N S E + E+ + V E+ KR + +E+
Sbjct: 472 NESKNETVSSNSSNNTGNSTTETSSTLEVRTQGPILTASGKNPVMELNEKRR-GLKYELI 530
Query: 125 RESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLPPLPAVERVKPRI 184
E+G H K FV +V V G G +KK++K +AA+A LE+L P A K +I
Sbjct: 531 SETGGSHDKRFVMEVEVDGQKFRGAGPNKKVAKASAALAALEKLFSGP--NAANNKKKKI 588
Query: 185 KKKTKPIVKPQTS 197
+ K +V S
Sbjct: 589 IPQAKGVVNTAVS 601
Score = 37.7 bits (86), Expect = 0.024
Identities = 23/70 (32%), Positives = 36/70 (51%), Gaps = 5/70 (7%)
Query: 204 INPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNA 263
+N + RL QI+ +Y LL++ G F M V V T E +G +KK AK +
Sbjct: 389 MNALMRLNQIRPGL-----QYKLLSQSGPVHAPVFTMSVDVDGTTYEASGPSKKTAKLHV 443
Query: 264 AENMLEILGF 273
A +L+ +G+
Sbjct: 444 AVKVLQAMGY 453
>gi|208431829 eukaryotic translation initiation factor 2-alpha
kinase 2 isoform b [Homo sapiens]
Length = 510
Score = 46.2 bits (108), Expect = 7e-05
Identities = 47/158 (29%), Positives = 71/158 (44%), Gaps = 24/158 (15%)
Query: 114 KRNLPVNFEVARESGPPHMKNFVTKVSV-GEFVGEGEGKSKKISKKNAAIAVLEELKKLP 172
K+ + + ++ SGPPH + F +V + G EGEG+SKK +K AA +E L K
Sbjct: 20 KQGVVLKYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSKKEAKNAAAKLAVEILNK-- 77
Query: 173 PLPAVERVKPRIKKKTKPIVKPQTSP----EYGQGINPISRLAQIQQAKKEKEPEYTLLT 228
KK P++ T+ G I I+R+AQ KK Y
Sbjct: 78 -----------EKKAVSPLLLTTTNSSEGLSMGNYIGLINRIAQ----KKRLTVNYEQCA 122
Query: 229 ERGLPRRREFVMQVKVG-NHTAEGTGTNKKVAKRNAAE 265
G+ F + K+G + GTG+ K+ AK+ AA+
Sbjct: 123 S-GVHGPEGFHYKCKMGQKEYSIGTGSTKQEAKQLAAK 159
Score = 33.9 bits (76), Expect = 0.35
Identities = 22/59 (37%), Positives = 28/59 (47%), Gaps = 1/59 (1%)
Query: 223 EYTLLTERGLPRRREFVMQVKV-GNHTAEGTGTNKKVAKRNAAENMLEILGFKVPQAQP 280
+Y L G P R F QV + G EG G +KK AK AA+ +EIL + P
Sbjct: 26 KYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSKKEAKNAAAKLAVEILNKEKKAVSP 84
>gi|208431827 eukaryotic translation initiation factor 2-alpha
kinase 2 isoform a [Homo sapiens]
Length = 551
Score = 46.2 bits (108), Expect = 7e-05
Identities = 47/158 (29%), Positives = 71/158 (44%), Gaps = 24/158 (15%)
Query: 114 KRNLPVNFEVARESGPPHMKNFVTKVSV-GEFVGEGEGKSKKISKKNAAIAVLEELKKLP 172
K+ + + ++ SGPPH + F +V + G EGEG+SKK +K AA +E L K
Sbjct: 20 KQGVVLKYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSKKEAKNAAAKLAVEILNK-- 77
Query: 173 PLPAVERVKPRIKKKTKPIVKPQTSP----EYGQGINPISRLAQIQQAKKEKEPEYTLLT 228
KK P++ T+ G I I+R+AQ KK Y
Sbjct: 78 -----------EKKAVSPLLLTTTNSSEGLSMGNYIGLINRIAQ----KKRLTVNYEQCA 122
Query: 229 ERGLPRRREFVMQVKVG-NHTAEGTGTNKKVAKRNAAE 265
G+ F + K+G + GTG+ K+ AK+ AA+
Sbjct: 123 S-GVHGPEGFHYKCKMGQKEYSIGTGSTKQEAKQLAAK 159
Score = 33.9 bits (76), Expect = 0.35
Identities = 22/59 (37%), Positives = 28/59 (47%), Gaps = 1/59 (1%)
Query: 223 EYTLLTERGLPRRREFVMQVKV-GNHTAEGTGTNKKVAKRNAAENMLEILGFKVPQAQP 280
+Y L G P R F QV + G EG G +KK AK AA+ +EIL + P
Sbjct: 26 KYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSKKEAKNAAAKLAVEILNKEKKAVSP 84
>gi|4506103 eukaryotic translation initiation factor 2-alpha kinase
2 isoform a [Homo sapiens]
Length = 551
Score = 46.2 bits (108), Expect = 7e-05
Identities = 47/158 (29%), Positives = 71/158 (44%), Gaps = 24/158 (15%)
Query: 114 KRNLPVNFEVARESGPPHMKNFVTKVSV-GEFVGEGEGKSKKISKKNAAIAVLEELKKLP 172
K+ + + ++ SGPPH + F +V + G EGEG+SKK +K AA +E L K
Sbjct: 20 KQGVVLKYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSKKEAKNAAAKLAVEILNK-- 77
Query: 173 PLPAVERVKPRIKKKTKPIVKPQTSP----EYGQGINPISRLAQIQQAKKEKEPEYTLLT 228
KK P++ T+ G I I+R+AQ KK Y
Sbjct: 78 -----------EKKAVSPLLLTTTNSSEGLSMGNYIGLINRIAQ----KKRLTVNYEQCA 122
Query: 229 ERGLPRRREFVMQVKVG-NHTAEGTGTNKKVAKRNAAE 265
G+ F + K+G + GTG+ K+ AK+ AA+
Sbjct: 123 S-GVHGPEGFHYKCKMGQKEYSIGTGSTKQEAKQLAAK 159
Score = 33.9 bits (76), Expect = 0.35
Identities = 22/59 (37%), Positives = 28/59 (47%), Gaps = 1/59 (1%)
Query: 223 EYTLLTERGLPRRREFVMQVKV-GNHTAEGTGTNKKVAKRNAAENMLEILGFKVPQAQP 280
+Y L G P R F QV + G EG G +KK AK AA+ +EIL + P
Sbjct: 26 KYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSKKEAKNAAAKLAVEILNKEKKAVSP 84
>gi|8922077 adenosine deaminase, RNA-specific, B2 [Homo sapiens]
Length = 739
Score = 43.5 bits (101), Expect = 4e-04
Identities = 49/215 (22%), Positives = 75/215 (34%), Gaps = 58/215 (26%)
Query: 119 VNFEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLP------ 172
+ + ++GP H F V V EG G +KK +K AA L + P
Sbjct: 140 LQYRTVSQTGPVHAPVFAVAVEVNGLTFEGTGPTKKKAKMRAAELALRSFVQFPNACQAH 199
Query: 173 --------------------------------PLPAVERVKP-------------RIKKK 187
P P + +P R+ +
Sbjct: 200 LAMGGGPGPGTDFTSDQADFPDTLFQEFEPPAPRPGLAGGRPGDAALLSAAYGRRRLLCR 259
Query: 188 TKPIVKPQTSPEYGQGI-NPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGN 246
+V P + G NP+ L +++ + Y L E R R FVM V V
Sbjct: 260 ALDLVGPTPATPAAPGERNPVVLLNRLRAGLR-----YVCLAEPAERRARSFVMAVSVDG 314
Query: 247 HTAEGTGTNKKVAKRNAAENML-EILGFKVPQAQP 280
T EG+G +KK+A+ AA+ L E+ ++P P
Sbjct: 315 RTFEGSGRSKKLARGQAAQAALQELFDIQMPGHAP 349
Score = 32.3 bits (72), Expect = 1.0
Identities = 20/62 (32%), Positives = 31/62 (50%), Gaps = 2/62 (3%)
Query: 204 INPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNA 263
+ P + L Q+ + + + Y +++ G F + V+V T EGTG KK AK A
Sbjct: 124 VAPKNALVQLHELRPGLQ--YRTVSQTGPVHAPVFAVAVEVNGLTFEGTGPTKKKAKMRA 181
Query: 264 AE 265
AE
Sbjct: 182 AE 183
Score = 29.6 bits (65), Expect = 6.6
Identities = 16/38 (42%), Positives = 21/38 (55%)
Query: 40 PVPPLLYQVELSVGGQQFNGKGKTRQAAKHDAAAKALR 77
PV ++ V + V G F G G T++ AK AA ALR
Sbjct: 150 PVHAPVFAVAVEVNGLTFEGTGPTKKKAKMRAAELALR 187
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.132 0.377
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,400,039
Number of Sequences: 37866
Number of extensions: 1053978
Number of successful extensions: 2662
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 34
Number of HSP's successfully gapped in prelim test: 58
Number of HSP's that attempted gapping in prelim test: 2448
Number of HSP's gapped (non-prelim): 209
length of query: 496
length of database: 18,247,518
effective HSP length: 106
effective length of query: 390
effective length of database: 14,233,722
effective search space: 5551151580
effective search space used: 5551151580
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.