Guide to the Human Genome
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Search of human proteins with 7706527

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|7706527 A-kinase anchor protein 7 isoform gamma [Homo
sapiens]
         (326 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|7706527 A-kinase anchor protein 7 isoform gamma [Homo sapiens]     650   0.0  
gi|20336196 A-kinase anchor protein 7 isoform beta [Homo sapiens]     132   4e-31
gi|4757738 A-kinase anchor protein 7 isoform alpha [Homo sapiens]     131   7e-31
gi|223633927 hypothetical protein LOC642597 [Homo sapiens]             45   9e-05
gi|239758069 PREDICTED: similar to FSHD region gene 1 isoform 2 ...    32   1.0  
gi|45446740 ATP-binding cassette, sub-family A, member 2 isoform...    32   1.0  
gi|47078218 ATP-binding cassette, sub-family A, member 2 isoform...    32   1.0  
gi|149274648 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like [Hom...    31   1.7  
gi|40805104 topoisomerase I binding, arginine/serine-rich [Homo ...    30   2.9  
gi|68077168 DnaJ homology subfamily A member 5 isoform 1 [Homo s...    30   3.8  
gi|119395727 cardiac calsequestrin 2 precursor [Homo sapiens]          29   5.0  
gi|222418587 hypothetical protein LOC57495 [Homo sapiens]              29   6.5  
gi|183227688 adenylosuccinate lyase isoform b [Homo sapiens]           29   6.5  
gi|4557269 adenylosuccinate lyase isoform a [Homo sapiens]             29   6.5  
gi|7657218 bromodomain-containing protein 4 isoform short [Homo ...    28   8.5  
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ...    28   8.5  
gi|10947135 ATP-binding cassette, sub-family F, member 1 isoform...    28   8.5  
gi|69354671 ATP-binding cassette, sub-family F, member 1 isoform...    28   8.5  
gi|38708169 sorting nexin 25 [Homo sapiens]                            28   8.5  

>gi|7706527 A-kinase anchor protein 7 isoform gamma [Homo sapiens]
          Length = 326

 Score =  650 bits (1676), Expect = 0.0
 Identities = 326/326 (100%), Positives = 326/326 (100%)

Query: 1   MSEEFEANTMDSLVDMPFATVDIQDDCGITDEPQINLKRSQENEWVKSDQVKKRKKKRKD 60
           MSEEFEANTMDSLVDMPFATVDIQDDCGITDEPQINLKRSQENEWVKSDQVKKRKKKRKD
Sbjct: 1   MSEEFEANTMDSLVDMPFATVDIQDDCGITDEPQINLKRSQENEWVKSDQVKKRKKKRKD 60

Query: 61  YQPNYFLSIPITNKEIIKGIKILQNAIIQQDERLAKAMVSDGSFHITLLVMQLLNEDEVN 120
           YQPNYFLSIPITNKEIIKGIKILQNAIIQQDERLAKAMVSDGSFHITLLVMQLLNEDEVN
Sbjct: 61  YQPNYFLSIPITNKEIIKGIKILQNAIIQQDERLAKAMVSDGSFHITLLVMQLLNEDEVN 120

Query: 121 IGIDALLELKPFIEELLQGKHLTLPFQGIGTFGNQVGFVKLAEGDHVNSLLEIAETANRT 180
           IGIDALLELKPFIEELLQGKHLTLPFQGIGTFGNQVGFVKLAEGDHVNSLLEIAETANRT
Sbjct: 121 IGIDALLELKPFIEELLQGKHLTLPFQGIGTFGNQVGFVKLAEGDHVNSLLEIAETANRT 180

Query: 181 FQEKGILVGESRSFKPHLTFMKLSKSPWLRKNGVKKIDPDLYEKFISHRFGEEILYRIDL 240
           FQEKGILVGESRSFKPHLTFMKLSKSPWLRKNGVKKIDPDLYEKFISHRFGEEILYRIDL
Sbjct: 181 FQEKGILVGESRSFKPHLTFMKLSKSPWLRKNGVKKIDPDLYEKFISHRFGEEILYRIDL 240

Query: 241 CSMLKKKQSNGYYHCESSIVIGEKNGGEPDDAELVRLSKRLVENAVLKAVQQYLEETQNK 300
           CSMLKKKQSNGYYHCESSIVIGEKNGGEPDDAELVRLSKRLVENAVLKAVQQYLEETQNK
Sbjct: 241 CSMLKKKQSNGYYHCESSIVIGEKNGGEPDDAELVRLSKRLVENAVLKAVQQYLEETQNK 300

Query: 301 NKPGEGSSVKTEAADQNGNDNENNRK 326
           NKPGEGSSVKTEAADQNGNDNENNRK
Sbjct: 301 NKPGEGSSVKTEAADQNGNDNENNRK 326


>gi|20336196 A-kinase anchor protein 7 isoform beta [Homo sapiens]
          Length = 104

 Score =  132 bits (332), Expect = 4e-31
 Identities = 65/65 (100%), Positives = 65/65 (100%)

Query: 262 GEKNGGEPDDAELVRLSKRLVENAVLKAVQQYLEETQNKNKPGEGSSVKTEAADQNGNDN 321
           GEKNGGEPDDAELVRLSKRLVENAVLKAVQQYLEETQNKNKPGEGSSVKTEAADQNGNDN
Sbjct: 40  GEKNGGEPDDAELVRLSKRLVENAVLKAVQQYLEETQNKNKPGEGSSVKTEAADQNGNDN 99

Query: 322 ENNRK 326
           ENNRK
Sbjct: 100 ENNRK 104


>gi|4757738 A-kinase anchor protein 7 isoform alpha [Homo sapiens]
          Length = 81

 Score =  131 bits (330), Expect = 7e-31
 Identities = 65/66 (98%), Positives = 65/66 (98%)

Query: 261 IGEKNGGEPDDAELVRLSKRLVENAVLKAVQQYLEETQNKNKPGEGSSVKTEAADQNGND 320
           I EKNGGEPDDAELVRLSKRLVENAVLKAVQQYLEETQNKNKPGEGSSVKTEAADQNGND
Sbjct: 16  ISEKNGGEPDDAELVRLSKRLVENAVLKAVQQYLEETQNKNKPGEGSSVKTEAADQNGND 75

Query: 321 NENNRK 326
           NENNRK
Sbjct: 76  NENNRK 81


>gi|223633927 hypothetical protein LOC642597 [Homo sapiens]
          Length = 69

 Score = 45.1 bits (105), Expect = 9e-05
 Identities = 19/41 (46%), Positives = 31/41 (75%)

Query: 262 GEKNGGEPDDAELVRLSKRLVENAVLKAVQQYLEETQNKNK 302
           GEK G EP++ +L   SK++V+NA+L+AVQQ  +E+Q + +
Sbjct: 6   GEKPGNEPEEVKLQNASKQIVQNAILQAVQQVSQESQRREE 46


>gi|239758069 PREDICTED: similar to FSHD region gene 1 isoform 2
           [Homo sapiens]
          Length = 124

 Score = 31.6 bits (70), Expect = 1.0
 Identities = 22/82 (26%), Positives = 35/82 (42%), Gaps = 14/82 (17%)

Query: 31  DEPQINLKRSQENEWVKSDQVKKRKKKRKDYQPNYFLSIPITNKEIIKGIKILQN---AI 87
           +E  I ++   E E  K D + + K   K Y+ NY           +K  +  Q+    I
Sbjct: 52  EEEMIKIRSCAERETKKKDDIPEDKGNVKQYEINY-----------VKKFQSFQDHKPKI 100

Query: 88  IQQDERLAKAMVSDGSFHITLL 109
            ++D ++ K    DG  H TLL
Sbjct: 101 SKEDSKILKKAQKDGFLHETLL 122


>gi|45446740 ATP-binding cassette, sub-family A, member 2 isoform a
            [Homo sapiens]
          Length = 2436

 Score = 31.6 bits (70), Expect = 1.0
 Identities = 15/44 (34%), Positives = 24/44 (54%)

Query: 16   MPFATVDIQDDCGITDEPQINLKRSQENEWVKSDQVKKRKKKRK 59
            MP +T  ++DD  +  E Q  L+   +N+ VK + + K  K RK
Sbjct: 2021 MPVSTKPVEDDVDVASERQRVLRGDADNDMVKIENLTKVYKSRK 2064


>gi|47078218 ATP-binding cassette, sub-family A, member 2 isoform b
            [Homo sapiens]
          Length = 2466

 Score = 31.6 bits (70), Expect = 1.0
 Identities = 15/44 (34%), Positives = 24/44 (54%)

Query: 16   MPFATVDIQDDCGITDEPQINLKRSQENEWVKSDQVKKRKKKRK 59
            MP +T  ++DD  +  E Q  L+   +N+ VK + + K  K RK
Sbjct: 2051 MPVSTKPVEDDVDVASERQRVLRGDADNDMVKIENLTKVYKSRK 2094


>gi|149274648 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like [Homo
            sapiens]
          Length = 1706

 Score = 30.8 bits (68), Expect = 1.7
 Identities = 19/57 (33%), Positives = 31/57 (54%), Gaps = 5/57 (8%)

Query: 36   NLKRSQENEWVKSDQVKKRKKKRKDYQPNYFLSIPITNKEIIKGIKILQNAIIQQDE 92
            NLK    N W+K+ QVKK K+  K+  P+   S    +K+++K   +L   + Q D+
Sbjct: 1055 NLKAELTN-WIKNGQVKKVKRVLKNLSPDSLSS----SKDMVKMFPLLVEKLRQMDK 1106


>gi|40805104 topoisomerase I binding, arginine/serine-rich [Homo
           sapiens]
          Length = 1045

 Score = 30.0 bits (66), Expect = 2.9
 Identities = 21/85 (24%), Positives = 37/85 (43%), Gaps = 4/85 (4%)

Query: 242 SMLKKKQSNGYYHCESSIVIGEKNGGEPDDAELVRLSKRLVENAVLKAVQQYLEETQNKN 301
           S+L K +     HC+SS  I  K     ++     LS     N+ ++  + Y        
Sbjct: 537 SVLGKDEQINKGHCDSSTRIKSKK----EEKRSTSLSSPRNLNSSVRGDRVYSPYNHRHR 592

Query: 302 KPGEGSSVKTEAADQNGNDNENNRK 326
           K G   S  + +  ++G+D +N+RK
Sbjct: 593 KRGRSRSSDSRSQSRSGHDQKNHRK 617


>gi|68077168 DnaJ homology subfamily A member 5 isoform 1 [Homo
           sapiens]
          Length = 576

 Score = 29.6 bits (65), Expect = 3.8
 Identities = 21/62 (33%), Positives = 32/62 (51%), Gaps = 12/62 (19%)

Query: 260 VIGEKNGGEPDDAELVRLSKRLVENAVLKAVQQYLEETQNKNKPGEGSSVKTEAADQNGN 319
           V+GE+  GE +     + +K L+EN      +Q  ++  N N PGEG  VK +  D N N
Sbjct: 418 VLGERRDGESEH----KCAKMLLEN------RQNYDDNFNVNGPGEG--VKVDPEDTNLN 465

Query: 320 DN 321
            +
Sbjct: 466 QD 467


>gi|119395727 cardiac calsequestrin 2 precursor [Homo sapiens]
          Length = 399

 Score = 29.3 bits (64), Expect = 5.0
 Identities = 28/142 (19%), Positives = 58/142 (40%), Gaps = 21/142 (14%)

Query: 89  QQDERLAKAMVSDGSFHITLL----VMQLLNEDEVNIGIDALLELKPFIEELLQGKHLTL 144
           +++ +LAK +  D    + +L     ++   E   ++ ++ LL+L     E++  K    
Sbjct: 97  KKEAKLAKKLGFDEEGSLYILKGDRTIEFDGEFAADVLVEFLLDLIEDPVEIISSKLEVQ 156

Query: 145 PFQGIGTFGNQVGFVKLAEGDHVNSLLEIAETANRTFQEKGILVGESRSFKPHLTFMKLS 204
            F+ I  +   +GF K  + ++  +  E AE                  F+P++ F    
Sbjct: 157 AFERIEDYIKLIGFFKSEDSEYYKAFEEAAE-----------------HFQPYIKFFATF 199

Query: 205 KSPWLRKNGVKKIDPDLYEKFI 226
                +K  +K  + D YE F+
Sbjct: 200 DKGVAKKLSLKMNEVDFYEPFM 221


>gi|222418587 hypothetical protein LOC57495 [Homo sapiens]
          Length = 1742

 Score = 28.9 bits (63), Expect = 6.5
 Identities = 23/97 (23%), Positives = 45/97 (46%), Gaps = 16/97 (16%)

Query: 146 FQGIGTFGNQVGFVKLAEGDHVNSLLEIAETANRTFQEKGILVGESRSFKPHLTFMKLSK 205
           F G+ + G +  F    E  ++N  L++         E   L+ E + F    +F + + 
Sbjct: 763 FLGVWSGGRRKAFC--LEDPYLNGCLDL---------ENRSLLEEEKHFMEQASFDRQAP 811

Query: 206 S-PWLRKNGVKKIDPDLYEKFISHRFGEEILYRIDLC 241
             PW+ +     ++PD++  F++HR   E+LY +  C
Sbjct: 812 DQPWVFQ--CNPLEPDIF--FVNHRKMSELLYHLTRC 844


>gi|183227688 adenylosuccinate lyase isoform b [Homo sapiens]
          Length = 425

 Score = 28.9 bits (63), Expect = 6.5
 Identities = 20/65 (30%), Positives = 33/65 (50%), Gaps = 2/65 (3%)

Query: 144 LPFQGI-GTFGNQVGFVKLAEG-DHVNSLLEIAETANRTFQEKGILVGESRSFKPHLTFM 201
           L F+G+ GT G Q  F++L EG DH    L+   T    F+   I+ G++ + K  +  +
Sbjct: 193 LRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITGQTYTRKVDIEVL 252

Query: 202 KLSKS 206
            +  S
Sbjct: 253 SVLAS 257


>gi|4557269 adenylosuccinate lyase isoform a [Homo sapiens]
          Length = 484

 Score = 28.9 bits (63), Expect = 6.5
 Identities = 20/65 (30%), Positives = 33/65 (50%), Gaps = 2/65 (3%)

Query: 144 LPFQGI-GTFGNQVGFVKLAEG-DHVNSLLEIAETANRTFQEKGILVGESRSFKPHLTFM 201
           L F+G+ GT G Q  F++L EG DH    L+   T    F+   I+ G++ + K  +  +
Sbjct: 193 LRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITGQTYTRKVDIEVL 252

Query: 202 KLSKS 206
            +  S
Sbjct: 253 SVLAS 257


>gi|7657218 bromodomain-containing protein 4 isoform short [Homo
           sapiens]
          Length = 722

 Score = 28.5 bits (62), Expect = 8.5
 Identities = 16/58 (27%), Positives = 29/58 (50%)

Query: 2   SEEFEANTMDSLVDMPFATVDIQDDCGITDEPQINLKRSQENEWVKSDQVKKRKKKRK 59
           S + +++T DS  +      ++Q+      E    L + Q+N+  K ++ KK KKK K
Sbjct: 493 SSDSDSSTDDSEEERAQRLAELQEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEK 550


>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
           sapiens]
          Length = 1362

 Score = 28.5 bits (62), Expect = 8.5
 Identities = 16/58 (27%), Positives = 29/58 (50%)

Query: 2   SEEFEANTMDSLVDMPFATVDIQDDCGITDEPQINLKRSQENEWVKSDQVKKRKKKRK 59
           S + +++T DS  +      ++Q+      E    L + Q+N+  K ++ KK KKK K
Sbjct: 493 SSDSDSSTDDSEEERAQRLAELQEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEK 550


>gi|10947135 ATP-binding cassette, sub-family F, member 1 isoform
          b [Homo sapiens]
          Length = 807

 Score = 28.5 bits (62), Expect = 8.5
 Identities = 17/68 (25%), Positives = 34/68 (50%), Gaps = 7/68 (10%)

Query: 33 PQINLKRSQENEWV-------KSDQVKKRKKKRKDYQPNYFLSIPITNKEIIKGIKILQN 85
          P+   ++  E EW+        SD+V K+ KK K  +  +F  + + +K+  +  K+L+ 
Sbjct: 2  PKAPKQQPPEPEWIGDGESTSPSDKVVKKGKKDKKIKKTFFEELAVEDKQAGEEEKVLKE 61

Query: 86 AIIQQDER 93
             QQ ++
Sbjct: 62 KEQQQQQQ 69


>gi|69354671 ATP-binding cassette, sub-family F, member 1 isoform
          a [Homo sapiens]
          Length = 845

 Score = 28.5 bits (62), Expect = 8.5
 Identities = 17/68 (25%), Positives = 34/68 (50%), Gaps = 7/68 (10%)

Query: 33 PQINLKRSQENEWV-------KSDQVKKRKKKRKDYQPNYFLSIPITNKEIIKGIKILQN 85
          P+   ++  E EW+        SD+V K+ KK K  +  +F  + + +K+  +  K+L+ 
Sbjct: 2  PKAPKQQPPEPEWIGDGESTSPSDKVVKKGKKDKKIKKTFFEELAVEDKQAGEEEKVLKE 61

Query: 86 AIIQQDER 93
             QQ ++
Sbjct: 62 KEQQQQQQ 69


>gi|38708169 sorting nexin 25 [Homo sapiens]
          Length = 840

 Score = 28.5 bits (62), Expect = 8.5
 Identities = 19/72 (26%), Positives = 32/72 (44%), Gaps = 6/72 (8%)

Query: 21  VDIQDDCGITDEPQINLKRSQENEWVKSDQVKKRKKKRKDYQPNYFLSIPITNKEIIKGI 80
           V+I     I+  PQ+   + +E   +K+D ++ R  KR      Y   + +  K+  K I
Sbjct: 205 VEIIQATTISSFPQLKRHKGKETAAMKADLLRARNMKR------YINQLTVAKKQCEKRI 258

Query: 81  KILQNAIIQQDE 92
           +IL      Q E
Sbjct: 259 RILGGPAYDQQE 270


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.134    0.374 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,551,610
Number of Sequences: 37866
Number of extensions: 486506
Number of successful extensions: 1227
Number of sequences better than 10.0: 19
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 1217
Number of HSP's gapped (non-prelim): 20
length of query: 326
length of database: 18,247,518
effective HSP length: 103
effective length of query: 223
effective length of database: 14,347,320
effective search space: 3199452360
effective search space used: 3199452360
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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