Guide to the Human Genome
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Search of human proteins with 7706451

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|7706451 G protein-coupled receptor, family C, group 5,
member B precursor [Homo sapiens]
         (403 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|7706451 G protein-coupled receptor, family C, group 5, member...   813   0.0  
gi|40217833 G protein-coupled receptor family C, group 5, member...   275   4e-74
gi|40217831 G protein-coupled receptor family C, group 5, member...   275   4e-74
gi|4506403 G protein-coupled receptor, family C, group 5, member...   193   2e-49
gi|8923705 G protein-coupled receptor, family C, group 5, member...   192   6e-49
gi|66529100 glutamate receptor, metabotropic 2 isoform a precurs...    67   4e-11
gi|46358417 glutamate receptor, metabotropic 3 precursor [Homo s...    66   5e-11
gi|194248052 glutamate receptor, metabotropic 2 isoform b [Homo ...    56   7e-08
gi|166999223 glutamate receptor, metabotropic 1 isoform beta pre...    53   6e-07
gi|166999098 glutamate receptor, metabotropic 1 isoform alpha pr...    53   6e-07
gi|187960069 glutamate receptor, metabotropic 8 isoform b precur...    48   1e-05
gi|187960067 glutamate receptor, metabotropic 8 isoform a precur...    48   1e-05
gi|37577159 calcium-sensing receptor [Homo sapiens]                    48   2e-05
gi|4504141 glutamate receptor, metabotropic 4 [Homo sapiens]           47   4e-05
gi|32528268 glutamate receptor, metabotropic 7 isoform b precurs...    45   2e-04
gi|4504147 glutamate receptor, metabotropic 7 isoform a precurso...    45   2e-04
gi|110611176 glutamate receptor, metabotropic 6 precursor [Homo ...    45   2e-04
gi|40255245 G protein-coupled receptor 51 [Homo sapiens]               40   0.004
gi|112807234 G protein-coupled receptor, family C, group 6, memb...    39   0.011
gi|23308585 G protein-coupled receptor 156 [Homo sapiens]              37   0.032
gi|190341091 feline leukemia virus subgroup C cellular receptor ...    31   2.3  
gi|150378545 POM121 membrane glycoprotein (rat)-like [Homo sapiens]    30   3.9  
gi|153792776 G protein-coupled receptor 171 [Homo sapiens]             30   3.9  
gi|26051278 nuclear pore membrane protein 121 [Homo sapiens]           30   5.1  
gi|110556646 transmembrane protein 8B isoform a [Homo sapiens]         29   6.6  
gi|110556642 transmembrane protein 8B isoform a [Homo sapiens]         29   6.6  
gi|239743232 PREDICTED: hypothetical protein XP_002342775 [Homo ...    29   6.6  

>gi|7706451 G protein-coupled receptor, family C, group 5, member B
           precursor [Homo sapiens]
          Length = 403

 Score =  813 bits (2099), Expect = 0.0
 Identities = 403/403 (100%), Positives = 403/403 (100%)

Query: 1   MFVASERKMRAHQVLTFLLLFVITSVASENASTSRGCGLDLLPQYVSLCDLDAIWGIVVE 60
           MFVASERKMRAHQVLTFLLLFVITSVASENASTSRGCGLDLLPQYVSLCDLDAIWGIVVE
Sbjct: 1   MFVASERKMRAHQVLTFLLLFVITSVASENASTSRGCGLDLLPQYVSLCDLDAIWGIVVE 60

Query: 61  AVAGAGALITLLLMLILLVRLPFIKEKEKKSPVGLHFLFLLGTLGLFGLTFAFIIQEDET 120
           AVAGAGALITLLLMLILLVRLPFIKEKEKKSPVGLHFLFLLGTLGLFGLTFAFIIQEDET
Sbjct: 61  AVAGAGALITLLLMLILLVRLPFIKEKEKKSPVGLHFLFLLGTLGLFGLTFAFIIQEDET 120

Query: 121 ICSVRRFLWGVLFALCFSCLLSQAWRVRRLVRHGTGPAGWQLVGLALCLMLVQVIIAVEW 180
           ICSVRRFLWGVLFALCFSCLLSQAWRVRRLVRHGTGPAGWQLVGLALCLMLVQVIIAVEW
Sbjct: 121 ICSVRRFLWGVLFALCFSCLLSQAWRVRRLVRHGTGPAGWQLVGLALCLMLVQVIIAVEW 180

Query: 181 LVLTVLRDTRPACAYEPMDFVMALIYDMVLLVVTLGLALFTLCGKFKRWKLNGAFLLITA 240
           LVLTVLRDTRPACAYEPMDFVMALIYDMVLLVVTLGLALFTLCGKFKRWKLNGAFLLITA
Sbjct: 181 LVLTVLRDTRPACAYEPMDFVMALIYDMVLLVVTLGLALFTLCGKFKRWKLNGAFLLITA 240

Query: 241 FLSVLIWVAWMTMYLFGNVKLQQGDAWNDPTLAITLAASGWVFVIFHAIPEIHCTLLPAL 300
           FLSVLIWVAWMTMYLFGNVKLQQGDAWNDPTLAITLAASGWVFVIFHAIPEIHCTLLPAL
Sbjct: 241 FLSVLIWVAWMTMYLFGNVKLQQGDAWNDPTLAITLAASGWVFVIFHAIPEIHCTLLPAL 300

Query: 301 QENTPNYFDTSQPRMRETAFEEDVQLPRAYMENKAFSMDEHNAALRTAGFPNGSLGKRPS 360
           QENTPNYFDTSQPRMRETAFEEDVQLPRAYMENKAFSMDEHNAALRTAGFPNGSLGKRPS
Sbjct: 301 QENTPNYFDTSQPRMRETAFEEDVQLPRAYMENKAFSMDEHNAALRTAGFPNGSLGKRPS 360

Query: 361 GSLGKRPSAPFRSNVYQPTEMAVVLNGGTIPTAPPSHTGRHLW 403
           GSLGKRPSAPFRSNVYQPTEMAVVLNGGTIPTAPPSHTGRHLW
Sbjct: 361 GSLGKRPSAPFRSNVYQPTEMAVVLNGGTIPTAPPSHTGRHLW 403


>gi|40217833 G protein-coupled receptor family C, group 5, member C
           isoform b [Homo sapiens]
          Length = 453

 Score =  275 bits (704), Expect = 4e-74
 Identities = 160/395 (40%), Positives = 226/395 (57%), Gaps = 34/395 (8%)

Query: 8   KMRAHQVLTFLL---LFVITSVASENASTSRGCGLDLLPQYVSLCDLDAIWGIVVEAVAG 64
           +M  H+ L   L   LF+     ++      GC   L P Y +LCD    WGIV+EAVAG
Sbjct: 12  RMAIHKALVMCLGLPLFLFPGAWAQG-HVPPGCSQGLNPLYYNLCDRSGAWGIVLEAVAG 70

Query: 65  AGALITLLLMLILLVRLPFIKEKEKKSPVGLHFLFLLGTLGLFGLTFAFIIQEDETICSV 124
           AG + T +L +IL+  LPF+++ +K+S +G    FLLGTLGLF L FA +++ D + C+ 
Sbjct: 71  AGIVTTFVLTIILVASLPFVQDTKKRSLLGTQVFFLLGTLGLFCLVFACVVKPDFSTCAS 130

Query: 125 RRFLWGVLFALCFSCLLSQAWRVRRLVRHGTGPAGWQLVGLALCLMLVQVIIAVEWLVLT 184
           RRFL+GVLFA+CFSCL +  + +  L R   GP GW +  +AL L LV+VII  EWL++T
Sbjct: 131 RRFLFGVLFAICFSCLAAHVFALNFLARKNHGPRGWVIFTVALLLTLVEVIINTEWLIIT 190

Query: 185 VLRDT---------------RPACAYEPMDFVMALIYDMVLLVVTLGLALFTLCGKFKRW 229
           ++R +                  CA   MDFVMALIY M+LL+     A   LCG++KRW
Sbjct: 191 LVRGSGEGGPQGNSSAGWAVASPCAIANMDFVMALIYVMLLLLGAFLGAWPALCGRYKRW 250

Query: 230 KLNGAFLLITAFLSVLIWVAWMTMYLFGNVKLQQGDAWNDPTLAITLAASGWVFVIFHAI 289
           + +G F+L+T   SV IWV W+ MY +GN K      W+DPTLAI LAA+ W FV+F+ I
Sbjct: 251 RKHGVFVLLTTATSVAIWVVWIVMYTYGN-KQHNSPTWDDPTLAIALAANAWAFVLFYVI 309

Query: 290 PEIHCTLLPALQENTPNYFDTSQPRMRETAFEEDVQLPRAYMENKAFSMDEHNAALRTAG 349
           PE+      + +++       ++    ET  +E  +    ++ENKAFSMDE  AA R   
Sbjct: 310 PEVSQVTKSSPEQSYQGDMYPTRGVGYETILKEQ-KGQSMFVENKAFSMDEPVAAKRPVS 368

Query: 350 FPNGSLGKRPSGSLGKRPSAPFRSNVYQPTEMAVV 384
             +G  G+               ++VYQPTEMA++
Sbjct: 369 PYSGYNGQ-------------LLTSVYQPTEMALM 390


>gi|40217831 G protein-coupled receptor family C, group 5, member C
           isoform a [Homo sapiens]
          Length = 486

 Score =  275 bits (704), Expect = 4e-74
 Identities = 160/395 (40%), Positives = 226/395 (57%), Gaps = 34/395 (8%)

Query: 8   KMRAHQVLTFLL---LFVITSVASENASTSRGCGLDLLPQYVSLCDLDAIWGIVVEAVAG 64
           +M  H+ L   L   LF+     ++      GC   L P Y +LCD    WGIV+EAVAG
Sbjct: 45  RMAIHKALVMCLGLPLFLFPGAWAQG-HVPPGCSQGLNPLYYNLCDRSGAWGIVLEAVAG 103

Query: 65  AGALITLLLMLILLVRLPFIKEKEKKSPVGLHFLFLLGTLGLFGLTFAFIIQEDETICSV 124
           AG + T +L +IL+  LPF+++ +K+S +G    FLLGTLGLF L FA +++ D + C+ 
Sbjct: 104 AGIVTTFVLTIILVASLPFVQDTKKRSLLGTQVFFLLGTLGLFCLVFACVVKPDFSTCAS 163

Query: 125 RRFLWGVLFALCFSCLLSQAWRVRRLVRHGTGPAGWQLVGLALCLMLVQVIIAVEWLVLT 184
           RRFL+GVLFA+CFSCL +  + +  L R   GP GW +  +AL L LV+VII  EWL++T
Sbjct: 164 RRFLFGVLFAICFSCLAAHVFALNFLARKNHGPRGWVIFTVALLLTLVEVIINTEWLIIT 223

Query: 185 VLRDT---------------RPACAYEPMDFVMALIYDMVLLVVTLGLALFTLCGKFKRW 229
           ++R +                  CA   MDFVMALIY M+LL+     A   LCG++KRW
Sbjct: 224 LVRGSGEGGPQGNSSAGWAVASPCAIANMDFVMALIYVMLLLLGAFLGAWPALCGRYKRW 283

Query: 230 KLNGAFLLITAFLSVLIWVAWMTMYLFGNVKLQQGDAWNDPTLAITLAASGWVFVIFHAI 289
           + +G F+L+T   SV IWV W+ MY +GN K      W+DPTLAI LAA+ W FV+F+ I
Sbjct: 284 RKHGVFVLLTTATSVAIWVVWIVMYTYGN-KQHNSPTWDDPTLAIALAANAWAFVLFYVI 342

Query: 290 PEIHCTLLPALQENTPNYFDTSQPRMRETAFEEDVQLPRAYMENKAFSMDEHNAALRTAG 349
           PE+      + +++       ++    ET  +E  +    ++ENKAFSMDE  AA R   
Sbjct: 343 PEVSQVTKSSPEQSYQGDMYPTRGVGYETILKEQ-KGQSMFVENKAFSMDEPVAAKRPVS 401

Query: 350 FPNGSLGKRPSGSLGKRPSAPFRSNVYQPTEMAVV 384
             +G  G+               ++VYQPTEMA++
Sbjct: 402 PYSGYNGQ-------------LLTSVYQPTEMALM 423


>gi|4506403 G protein-coupled receptor, family C, group 5, member A
           [Homo sapiens]
          Length = 357

 Score =  193 bits (491), Expect = 2e-49
 Identities = 117/320 (36%), Positives = 180/320 (56%), Gaps = 20/320 (6%)

Query: 36  GCGLDLLPQYVSLCDLDAIWGIVVEAVAGAGALITLLLMLILLVRLPFIKEKEKKSPVGL 95
           GC   L  +Y  LCD    WGIV+E VA AG + ++  ML L + +  +++  ++  +  
Sbjct: 8   GCRNGLKSKYYRLCDKAEAWGIVLETVATAGVVTSVAFMLTLPILVCKVQDSNRRKMLPT 67

Query: 96  HFLFLLGTLGLFGLTFAFIIQEDETICSVRRFLWGVLFALCFSCLLSQAWRVRRLVRHGT 155
            FLFLLG LG+FGLTFAFII  D +    R FL+G+LF++CFSCLL+ A  + +LVR   
Sbjct: 68  QFLFLLGVLGIFGLTFAFIIGLDGSTGPTRFFLFGILFSICFSCLLAHAVSLTKLVRGRK 127

Query: 156 GPAGWQLVGLALCLMLVQVIIAVEWLVLTVLRD-----TRPACAYEPMDFVMALIYDMVL 210
             +   ++GLA+   LVQ +IA+E++VLT+ R      +  +      DFV+ L Y + L
Sbjct: 128 PLSLLVILGLAVGFSLVQDVIAIEYIVLTMNRTNVNVFSELSAPRRNEDFVLLLTYVLFL 187

Query: 211 LVVTLGLALFTLCGKFKRWKLNGAFLLITAFLSVLIWVAWMTMYLFGNVKLQQGDAWNDP 270
           + +T  ++ FT CG F  WK +GA + +T  LS+ IWVAW+T+ +  +   +    W+D 
Sbjct: 188 MALTFLMSSFTFCGSFTGWKRHGAHIYLTMLLSIAIWVAWITLLMLPDFDRR----WDDT 243

Query: 271 TLAITLAASGWVFVIFHAIPEIHCTLLPALQENTPNYFDTSQPRMRETAFEEDVQLPRAY 330
            L+  LAA+GWVF++ +  PE     L   Q N  +Y         E AF +   + ++Y
Sbjct: 244 ILSSALAANGWVFLLAYVSPEF---WLLTKQRNPMDY-------PVEDAFCKPQLVKKSY 293

Query: 331 -MENKAFSMDEHNAALRTAG 349
            +EN+A+S +E        G
Sbjct: 294 GVENRAYSQEEITQGFEETG 313


>gi|8923705 G protein-coupled receptor, family C, group 5, member D
           [Homo sapiens]
          Length = 345

 Score =  192 bits (487), Expect = 6e-49
 Identities = 110/312 (35%), Positives = 179/312 (57%), Gaps = 11/312 (3%)

Query: 45  YVSLCDLDAIWGIVVEAVAGAGALITLLLMLILLVRLPFIKEKEKKSPVGLHFLFLLGTL 104
           Y  LCD +  WGI++E++A  G ++T+LL+L  L  +  I++  + + +    LFLL  L
Sbjct: 12  YFLLCDAEGPWGIILESLAILGIVVTILLLLAFLFLMRKIQDCSQWNVLPTQLLFLLSVL 71

Query: 105 GLFGLTFAFIIQEDETICSVRRFLWGVLFALCFSCLLSQAWRVRRLVRHGTGPAGWQLVG 164
           GLFGL FAFII+ ++    VR FL+GVLFALCFSCLL+ A  + +LVR     +   ++ 
Sbjct: 72  GLFGLAFAFIIELNQQTAPVRYFLFGVLFALCFSCLLAHASNLVKLVRGCVSFSWTTILC 131

Query: 165 LALCLMLVQVIIAVEWLVLTVLRD----TRPACAYEPMDFVMALIYDMVLLVVTLGLALF 220
           +A+   L+Q+IIA E++ L + R         C    +DFV+ L+Y + L+ +T  ++  
Sbjct: 132 IAIGCSLLQIIIATEYVTLIMTRGMMFVNMTPCQLN-VDFVVLLVYVLFLMALTFFVSKA 190

Query: 221 TLCGKFKRWKLNGAFLLITAFLSVLIWVAWMTMYLFGNVKLQQGDAWNDPTLAITLAASG 280
           T CG  + WK +G  + IT   S++IWV W++M L GN + Q+   W+DP + I L  + 
Sbjct: 191 TFCGPCENWKQHGRLIFITVLFSIIIWVVWISMLLRGNPQFQRQPQWDDPVVCIALVTNA 250

Query: 281 WVFVIFHAIPEIHCTLLPALQENTPNYFDTSQPRMRETAFE-EDVQLPRAYMENKAFSMD 339
           WVF++ + +PE+ C L  + ++  P   +       + +F+ E+ +L RA   + A    
Sbjct: 251 WVFLLLYIVPEL-CILYRSCRQECPLQGNACPVTAYQHSFQVENQELSRARDSDGA---- 305

Query: 340 EHNAALRTAGFP 351
           E + AL + G P
Sbjct: 306 EEDVALTSYGTP 317


>gi|66529100 glutamate receptor, metabotropic 2 isoform a precursor
           [Homo sapiens]
          Length = 872

 Score = 66.6 bits (161), Expect = 4e-11
 Identities = 74/296 (25%), Positives = 136/296 (45%), Gaps = 53/296 (17%)

Query: 30  NASTSRGCGLDLLPQYVSLCDLDAIWGIVVEAVAGAGALITLLLMLILLVR--LPFIKEK 87
           NAS + GC  +L  +Y+   D    W +    +A  GAL TL ++ + +     P +K  
Sbjct: 547 NASLT-GC-FELPQEYIRWGDA---WAVGPVTIACLGALATLFVLGVFVRHNATPVVKAS 601

Query: 88  EKKSPVGLHFLFLLGTLGLFGLTFAFIIQEDETICSVRRFLWGVLFALCFSCLLSQAWRV 147
            ++    L ++ L G    + +TF FI +    +C++RR   G  F++C+S LL++  R+
Sbjct: 602 GRE----LCYILLGGVFLCYCMTFIFIAKPSTAVCTLRRLGLGTAFSVCYSALLTKTNRI 657

Query: 148 RRL---VRHGT------GPAGWQLVGLALCLMLV--QVIIAVEWLVLTVL---RDTRP-- 191
            R+    R G        PA      +A+CL L+  Q++I V WLV+      ++T P  
Sbjct: 658 ARIFGGAREGAQRPRFISPAS----QVAICLALISGQLLIVVAWLVVEAPGTGKETAPER 713

Query: 192 ------ACAYEPMDFVMALIYDMVLLVVTLGLALFTLCGKFKRWKL-----NGAFLLITA 240
                  C +     + +L Y+++L      +AL TL   FK  K         F+  T 
Sbjct: 714 REVVTLRCNHRDASMLGSLAYNVLL------IALCTLYA-FKTRKCPENFNEAKFIGFTM 766

Query: 241 FLSVLIWVAWMTMYLFGNVKLQQGDAWNDPTLAITLAASGWVFVIFHAIPEIHCTL 296
           + + +IW+A++ ++   +   +        T+ ++++ SG V +     P++H  L
Sbjct: 767 YTTCIIWLAFLPIFYVTSSDYRV----QTTTMCVSVSLSGSVVLGCLFAPKLHIIL 818


>gi|46358417 glutamate receptor, metabotropic 3 precursor [Homo
           sapiens]
          Length = 879

 Score = 66.2 bits (160), Expect = 5e-11
 Identities = 66/281 (23%), Positives = 128/281 (45%), Gaps = 34/281 (12%)

Query: 36  GCGLDLLPQYVSLCDLDAIWGIVVEAVAGAGALITLLLMLILLVR--LPFIKEKEKKSPV 93
           GC  DL   Y+   D    W I    +A  G + T +++ + +     P +K   ++   
Sbjct: 561 GC-YDLPEDYIRWEDA---WAIGPVTIACLGFMCTCMVVTVFIKHNNTPLVKASGRE--- 613

Query: 94  GLHFLFLLGTLGLFGLTFAFIIQEDETICSVRRFLWGVLFALCFSCLLSQAWRVRRL--- 150
            L ++ L G    + +TF FI +    IC++RR   G  FA+C+S LL++   + R+   
Sbjct: 614 -LCYILLFGVGLSYCMTFFFIAKPSPVICALRRLGLGSSFAICYSALLTKTNCIARIFDG 672

Query: 151 VRHGTGPAGW----QLVGLALCLMLVQVIIAVEWLVLT-------VLRDTRPA----CAY 195
           V++G     +      V + L L+LVQ+++   WL+L         L + R      C  
Sbjct: 673 VKNGAQRPKFISPSSQVFICLGLILVQIVMVSVWLILEAPGTRRYTLAEKRETVILKCNV 732

Query: 196 EPMDFVMALIYDMVLLVVTLGLALFTLCGKFKRWKLNGAFLLITAFLSVLIWVAWMTMYL 255
           +    +++L YD++L+++    A  T   K         F+  T + + +IW+A++ ++ 
Sbjct: 733 KDSSMLISLTYDVILVILCTVYAFKT--RKCPENFNEAKFIGFTMYTTCIIWLAFLPIFY 790

Query: 256 FGNVKLQQGDAWNDPTLAITLAASGWVFVIFHAIPEIHCTL 296
             +   +        T+ I+++ SG+V +     P++H  L
Sbjct: 791 VTSSDYRV----QTTTMCISVSLSGFVVLGCLFAPKVHIIL 827


>gi|194248052 glutamate receptor, metabotropic 2 isoform b [Homo
           sapiens]
          Length = 254

 Score = 55.8 bits (133), Expect = 7e-08
 Identities = 54/215 (25%), Positives = 100/215 (46%), Gaps = 42/215 (19%)

Query: 109 LTFAFIIQEDETICSVRRFLWGVLFALCFSCLLSQAWRVRRL---VRHGT------GPAG 159
           +TF FI +    +C++RR   G  F++C+S LL++  R+ R+    R G        PA 
Sbjct: 1   MTFIFIAKPSTAVCTLRRLGLGTAFSVCYSALLTKTNRIARIFGGAREGAQRPRFISPAS 60

Query: 160 WQLVGLALCLMLV--QVIIAVEWLVLTVL---RDTRP--------ACAYEPMDFVMALIY 206
                +A+CL L+  Q++I V WLV+      ++T P         C +     + +L Y
Sbjct: 61  ----QVAICLALISGQLLIVVAWLVVEAPGTGKETAPERREVVTLRCNHRDASMLGSLAY 116

Query: 207 DMVLLVVTLGLALFTLCGKFKRWKL-----NGAFLLITAFLSVLIWVAWMTMYLFGNVKL 261
           +++L      +AL TL   FK  K         F+  T + + +IW+A++ ++   +   
Sbjct: 117 NVLL------IALCTLYA-FKTRKCPENFNEAKFIGFTMYTTCIIWLAFLPIFYVTSSDY 169

Query: 262 QQGDAWNDPTLAITLAASGWVFVIFHAIPEIHCTL 296
           +        T+ ++++ SG V +     P++H  L
Sbjct: 170 RV----QTTTMCVSVSLSGSVVLGCLFAPKLHIIL 200


>gi|166999223 glutamate receptor, metabotropic 1 isoform beta
           precursor [Homo sapiens]
          Length = 906

 Score = 52.8 bits (125), Expect = 6e-07
 Identities = 51/230 (22%), Positives = 102/230 (44%), Gaps = 30/230 (13%)

Query: 54  IWGIVVEAVAGAGALITLLLMLILLVR--LPFIKEKEKKSPVGLHFLFLLGTLGLFGLTF 111
           I  I+  A +  G L+TL + LI ++    P +K   ++    L ++ L G    +   F
Sbjct: 591 IESIIAIAFSCLGILVTLFVTLIFVLYRDTPVVKSSSRE----LCYIILAGIFLGYVCPF 646

Query: 112 AFIIQEDETICSVRRFLWGVLFALCFSCLLSQAWRVRRLV---------RHGTGPAGWQL 162
             I +   T C ++R L G+  A+C+S L+++  R+ R++         R     + W  
Sbjct: 647 TLIAKPTTTSCYLQRLLVGLSSAMCYSALVTKTNRIARILAGSKKKICTRKPRFMSAWAQ 706

Query: 163 VGLALCLMLVQVIIAVEWLVL---------TVLRDTRPACAYEPMDFVMALIYDMVLLVV 213
           V +A  L+ VQ+ + V  +++           +++    C    +  V  L Y+ +L++ 
Sbjct: 707 VIIASILISVQLTLVVTLIIMEPPMPILSYPSIKEVYLICNTSNLGVVAPLGYNGLLIMS 766

Query: 214 TLGLALFT--LCGKFKRWKLNGAFLLITAFLSVLIWVAWMTMYLFGNVKL 261
               A  T  +   F   K    ++  T + + +IW+A++ +Y   N K+
Sbjct: 767 CTYYAFKTRNVPANFNEAK----YIAFTMYTTCIIWLAFVPIYFGSNYKI 812


>gi|166999098 glutamate receptor, metabotropic 1 isoform alpha
           precursor [Homo sapiens]
          Length = 1194

 Score = 52.8 bits (125), Expect = 6e-07
 Identities = 51/230 (22%), Positives = 102/230 (44%), Gaps = 30/230 (13%)

Query: 54  IWGIVVEAVAGAGALITLLLMLILLVR--LPFIKEKEKKSPVGLHFLFLLGTLGLFGLTF 111
           I  I+  A +  G L+TL + LI ++    P +K   ++    L ++ L G    +   F
Sbjct: 591 IESIIAIAFSCLGILVTLFVTLIFVLYRDTPVVKSSSRE----LCYIILAGIFLGYVCPF 646

Query: 112 AFIIQEDETICSVRRFLWGVLFALCFSCLLSQAWRVRRLV---------RHGTGPAGWQL 162
             I +   T C ++R L G+  A+C+S L+++  R+ R++         R     + W  
Sbjct: 647 TLIAKPTTTSCYLQRLLVGLSSAMCYSALVTKTNRIARILAGSKKKICTRKPRFMSAWAQ 706

Query: 163 VGLALCLMLVQVIIAVEWLVL---------TVLRDTRPACAYEPMDFVMALIYDMVLLVV 213
           V +A  L+ VQ+ + V  +++           +++    C    +  V  L Y+ +L++ 
Sbjct: 707 VIIASILISVQLTLVVTLIIMEPPMPILSYPSIKEVYLICNTSNLGVVAPLGYNGLLIMS 766

Query: 214 TLGLALFT--LCGKFKRWKLNGAFLLITAFLSVLIWVAWMTMYLFGNVKL 261
               A  T  +   F   K    ++  T + + +IW+A++ +Y   N K+
Sbjct: 767 CTYYAFKTRNVPANFNEAK----YIAFTMYTTCIIWLAFVPIYFGSNYKI 812


>gi|187960069 glutamate receptor, metabotropic 8 isoform b precursor
           [Homo sapiens]
          Length = 908

 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 60/268 (22%), Positives = 112/268 (41%), Gaps = 40/268 (14%)

Query: 55  WGIVVEAVAGAGALITLLLMLILLVRL---PFIKEKEKKSPVGLHFLFLLGTLGLFGLTF 111
           W +V   VA  G + T  + ++  VR    P ++   ++    L ++ L G    + +TF
Sbjct: 583 WAVVPVFVAILGIIATTFV-IVTFVRYNDTPIVRASGRE----LSYVLLTGIFLCYSITF 637

Query: 112 AFIIQEDETICSVRRFLWGVLFALCFSCLLSQAWRVRRLVRHG----TGP----AGWQLV 163
             I   D  ICS RR   G+     ++ LL++  R+ R+   G    T P       QLV
Sbjct: 638 LMIAAPDTIICSFRRVFLGLGMCFSYAALLTKTNRIHRIFEQGKKSVTAPKFISPASQLV 697

Query: 164 GLALCLMLVQVIIAVEWLVLT---------VLRDTRP-------ACAYEPMDFVMALIYD 207
            +   L+ VQ++    W V+            R   P        C    +  + +L Y 
Sbjct: 698 -ITFSLISVQLLGVFVWFVVDPPHIIIDYGEQRTLDPEKARGVLKCDISDLSLICSLGYS 756

Query: 208 MVLLVVTLGLALFT--LCGKFKRWKLNGAFLLITAFLSVLIWVAWMTMYLFGNVKLQQGD 265
           ++L+V     A+ T  +   F   K  G     T + + +IW+A++ ++ FG  +  +  
Sbjct: 757 ILLMVTCTVYAIKTRGVPETFNEAKPIG----FTMYTTCIIWLAFIPIF-FGTAQSAEKM 811

Query: 266 AWNDPTLAITLAASGWVFVIFHAIPEIH 293
                TL ++++ S  V +    +P+++
Sbjct: 812 YIQTTTLTVSMSLSASVSLGMLYMPKVY 839


>gi|187960067 glutamate receptor, metabotropic 8 isoform a precursor
           [Homo sapiens]
          Length = 908

 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 60/268 (22%), Positives = 112/268 (41%), Gaps = 40/268 (14%)

Query: 55  WGIVVEAVAGAGALITLLLMLILLVRL---PFIKEKEKKSPVGLHFLFLLGTLGLFGLTF 111
           W +V   VA  G + T  + ++  VR    P ++   ++    L ++ L G    + +TF
Sbjct: 583 WAVVPVFVAILGIIATTFV-IVTFVRYNDTPIVRASGRE----LSYVLLTGIFLCYSITF 637

Query: 112 AFIIQEDETICSVRRFLWGVLFALCFSCLLSQAWRVRRLVRHG----TGP----AGWQLV 163
             I   D  ICS RR   G+     ++ LL++  R+ R+   G    T P       QLV
Sbjct: 638 LMIAAPDTIICSFRRVFLGLGMCFSYAALLTKTNRIHRIFEQGKKSVTAPKFISPASQLV 697

Query: 164 GLALCLMLVQVIIAVEWLVLT---------VLRDTRP-------ACAYEPMDFVMALIYD 207
            +   L+ VQ++    W V+            R   P        C    +  + +L Y 
Sbjct: 698 -ITFSLISVQLLGVFVWFVVDPPHIIIDYGEQRTLDPEKARGVLKCDISDLSLICSLGYS 756

Query: 208 MVLLVVTLGLALFT--LCGKFKRWKLNGAFLLITAFLSVLIWVAWMTMYLFGNVKLQQGD 265
           ++L+V     A+ T  +   F   K  G     T + + +IW+A++ ++ FG  +  +  
Sbjct: 757 ILLMVTCTVYAIKTRGVPETFNEAKPIG----FTMYTTCIIWLAFIPIF-FGTAQSAEKM 811

Query: 266 AWNDPTLAITLAASGWVFVIFHAIPEIH 293
                TL ++++ S  V +    +P+++
Sbjct: 812 YIQTTTLTVSMSLSASVSLGMLYMPKVY 839


>gi|37577159 calcium-sensing receptor [Homo sapiens]
          Length = 1078

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 53/225 (23%), Positives = 94/225 (41%), Gaps = 36/225 (16%)

Query: 55  WGIVVEAVAGAGALITLLLMLILLV--RLPFIKEKEKKSPVGLHFLFLLGTLGLFGLTFA 112
           +GI +   A  G  +T  ++ + +     P +K   ++    L +L L   L  F  +  
Sbjct: 612 FGIALTLFAVLGIFLTAFVLGVFIKFRNTPIVKATNRE----LSYLLLFSLLCCFSSSLF 667

Query: 113 FIIQEDETICSVRRFLWGVLFALCFSCLLSQAWRVRRLVRHGTGPAGW--QLVGLALCLM 170
           FI +  +  C +R+  +G+ F LC SC+L +  RV  LV     P  +  +  GL L  +
Sbjct: 668 FIGEPQDWTCRLRQPAFGISFVLCISCILVKTNRV-LLVFEAKIPTSFHRKWWGLNLQFL 726

Query: 171 LV------QVIIAVEWLVLTVLRDTRPACAYEPMDFVMALIY------DMVLLVVTLG-- 216
           LV      Q++I V WL       T P  +Y   +    +I+       ++ L   +G  
Sbjct: 727 LVFLCTFMQIVICVIWLY------TAPPSSYRNQELEDEIIFITCHEGSLMALGFLIGYT 780

Query: 217 --LALFTLCGKFKRWKL-----NGAFLLITAFLSVLIWVAWMTMY 254
             LA       FK  KL        F+  +  +  ++W++++  Y
Sbjct: 781 CLLAAICFFFAFKSRKLPENFNEAKFITFSMLIFFIVWISFIPAY 825


>gi|4504141 glutamate receptor, metabotropic 4 [Homo sapiens]
          Length = 912

 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 55/272 (20%), Positives = 112/272 (41%), Gaps = 39/272 (14%)

Query: 61  AVAGAGALITLLLMLILLVRLPFIKEKEKKSPVGLHFLFLLGTLGLFGLTFAFIIQEDET 120
           AV G  A + +++  +     P +K   ++    L ++ L G    +  TF  I + D  
Sbjct: 595 AVVGIAATLFVVITFVRYNDTPIVKASGRE----LSYVLLAGIFLCYATTFLMIAEPDLG 650

Query: 121 ICSVRRFLWGVLFALCFSCLLSQAWRVRRLVRHG---------TGPAGWQLVGLALCLML 171
            CS+RR   G+  ++ ++ LL++  R+ R+   G           PA    + +   L+ 
Sbjct: 651 TCSLRRIFLGLGMSISYAALLTKTNRIYRIFEQGKRSVSAPRFISPA--SQLAITFSLIS 708

Query: 172 VQVIIAVEWLV------LTVLRDTRP----------ACAYEPMDFVMALIYDMVLLVVTL 215
           +Q++    W V      +   +D R            C    +  +  L Y M+L+V   
Sbjct: 709 LQLLGICVWFVVDPSHSVVDFQDQRTLDPRFARGVLKCDISDLSLICLLGYSMLLMVTCT 768

Query: 216 GLALFT--LCGKFKRWKLNGAFLLITAFLSVLIWVAWMTMYLFGNVKLQQGDAWNDPTLA 273
             A+ T  +   F   K  G     T + + ++W+A++ ++ FG  +          TL 
Sbjct: 769 VYAIKTRGVPETFNEAKPIG----FTMYTTCIVWLAFIPIF-FGTSQSADKLYIQTTTLT 823

Query: 274 ITLAASGWVFVIFHAIPEIHCTLLPALQENTP 305
           ++++ S  V +    +P+++  L    ++N P
Sbjct: 824 VSVSLSASVSLGMLYMPKVYIILFHP-EQNVP 854


>gi|32528268 glutamate receptor, metabotropic 7 isoform b precursor
           [Homo sapiens]
          Length = 922

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 53/269 (19%), Positives = 111/269 (41%), Gaps = 42/269 (15%)

Query: 55  WGIVVEAVAGAGALITLLLM--LILLVRLPFIKEKEKKSPVGLHFLFLLGTLGLFGLTFA 112
           W ++   +A  G + T+ +M   I     P ++   ++    L ++ L G    + +TF 
Sbjct: 590 WAVIPVFLAMLGIIATIFVMATFIRYNDTPIVRASGRE----LSYVLLTGIFLCYIITFL 645

Query: 113 FIIQEDETICSVRRFLWGVLFALCFSCLLSQAWRVRRLVRHG----TGPAGWQLVGLALC 168
            I + D  +CS RR   G+   + ++ LL++  R+ R+   G    T P   +L+     
Sbjct: 646 MIAKPDVAVCSFRRVFLGLGMCISYAALLTKTNRIYRIFEQGKKSVTAP---RLISPTSQ 702

Query: 169 LMLVQVIIAVEWLVLTVLRDTRP----------------------ACAYEPMDFVMALIY 206
           L +   +I+V+ L + +     P                       C    +  + +L Y
Sbjct: 703 LAITSSLISVQLLGVFIWFGVDPPNIIIDYDEHKTMNPEQARGVLKCDITDLQIICSLGY 762

Query: 207 DMVLLVVTLGLALFT--LCGKFKRWKLNGAFLLITAFLSVLIWVAWMTMYLFGNVKLQQG 264
            ++L+V     A+ T  +   F   K  G     T + + ++W+A++ ++ FG  +  + 
Sbjct: 763 SILLMVTCTVYAIKTRGVPENFNEAKPIG----FTMYTTCIVWLAFIPIF-FGTAQSAEK 817

Query: 265 DAWNDPTLAITLAASGWVFVIFHAIPEIH 293
                 TL I++  S  V +    +P+++
Sbjct: 818 LYIQTTTLTISMNLSASVALGMLYMPKVY 846


>gi|4504147 glutamate receptor, metabotropic 7 isoform a precursor
           [Homo sapiens]
          Length = 915

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 53/269 (19%), Positives = 111/269 (41%), Gaps = 42/269 (15%)

Query: 55  WGIVVEAVAGAGALITLLLM--LILLVRLPFIKEKEKKSPVGLHFLFLLGTLGLFGLTFA 112
           W ++   +A  G + T+ +M   I     P ++   ++    L ++ L G    + +TF 
Sbjct: 590 WAVIPVFLAMLGIIATIFVMATFIRYNDTPIVRASGRE----LSYVLLTGIFLCYIITFL 645

Query: 113 FIIQEDETICSVRRFLWGVLFALCFSCLLSQAWRVRRLVRHG----TGPAGWQLVGLALC 168
            I + D  +CS RR   G+   + ++ LL++  R+ R+   G    T P   +L+     
Sbjct: 646 MIAKPDVAVCSFRRVFLGLGMCISYAALLTKTNRIYRIFEQGKKSVTAP---RLISPTSQ 702

Query: 169 LMLVQVIIAVEWLVLTVLRDTRP----------------------ACAYEPMDFVMALIY 206
           L +   +I+V+ L + +     P                       C    +  + +L Y
Sbjct: 703 LAITSSLISVQLLGVFIWFGVDPPNIIIDYDEHKTMNPEQARGVLKCDITDLQIICSLGY 762

Query: 207 DMVLLVVTLGLALFT--LCGKFKRWKLNGAFLLITAFLSVLIWVAWMTMYLFGNVKLQQG 264
            ++L+V     A+ T  +   F   K  G     T + + ++W+A++ ++ FG  +  + 
Sbjct: 763 SILLMVTCTVYAIKTRGVPENFNEAKPIG----FTMYTTCIVWLAFIPIF-FGTAQSAEK 817

Query: 265 DAWNDPTLAITLAASGWVFVIFHAIPEIH 293
                 TL I++  S  V +    +P+++
Sbjct: 818 LYIQTTTLTISMNLSASVALGMLYMPKVY 846


>gi|110611176 glutamate receptor, metabotropic 6 precursor [Homo
           sapiens]
          Length = 877

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 57/262 (21%), Positives = 109/262 (41%), Gaps = 36/262 (13%)

Query: 61  AVAGAGALITLLLMLILLVRLPFIKEKEKKSPVGLHFLFLLGTLGLFGLTFAFIIQEDET 120
           AV G  A  T++   +     P ++   ++    L ++ L G   ++ +TF  + +    
Sbjct: 593 AVLGIVATTTVVATFVRYNNTPIVRASGRE----LSYVLLTGIFLIYAITFLMVAEPGAA 648

Query: 121 ICSVRRFLWGVLFALCFSCLLSQAWRVRRLVRHG----TGP----AGWQLVGLALCLMLV 172
           +C+ RR   G+   L +S LL++  R+ R+   G    T P       QLV +   L  +
Sbjct: 649 VCAARRLFLGLGTTLSYSALLTKTNRIYRIFEQGKRSVTPPPFISPTSQLV-ITFSLTSL 707

Query: 173 QVIIAVEWLVL----TVL-----RDTRP-------ACAYEPMDFVMALIYDMVLLVVTLG 216
           QV+  + WL      +V+     R   P        C    +  +  L Y ++L+V    
Sbjct: 708 QVVGMIAWLGARPPHSVIDYEEQRTVDPEQARGVLKCDMSDLSLIGCLGYSLLLMVTCTV 767

Query: 217 LALFT--LCGKFKRWKLNGAFLLITAFLSVLIWVAWMTMYLFGNVKLQQGDAWNDPTLAI 274
            A+    +   F   K  G     T + + +IW+A++ ++ FG  +  +       TL +
Sbjct: 768 YAIKARGVPETFNEAKPIG----FTMYTTCIIWLAFVPIF-FGTAQSAEKIYIQTTTLTV 822

Query: 275 TLAASGWVFVIFHAIPEIHCTL 296
           +L+ S  V +    +P+ +  L
Sbjct: 823 SLSLSASVSLGMLYVPKTYVIL 844


>gi|40255245 G protein-coupled receptor 51 [Homo sapiens]
          Length = 941

 Score = 40.0 bits (92), Expect = 0.004
 Identities = 37/145 (25%), Positives = 70/145 (48%), Gaps = 16/145 (11%)

Query: 69  ITLLLMLILLVRLPF-IKEKEKK-----SPVGLHFLFLLGTLG-----LFGLTFAFIIQE 117
           +T+L M++    L F IK + +K     SP   + + L G L      LFGL  +F+ ++
Sbjct: 488 LTILGMIMASAFLFFNIKNRNQKLIKMSSPYMNNLIILGGMLSYASIFLFGLDGSFVSEK 547

Query: 118 D-ETICSVRRFLWGVLFALCFSCLLSQAWRVRRLVRHGTGP----AGWQLVGLALCLMLV 172
             ET+C+VR ++  V +   F  + ++ WRV  + ++           +L+ +   ++L+
Sbjct: 548 TFETLCTVRTWILTVGYTTAFGAMFAKTWRVHAIFKNVKMKKKIIKDQKLLVIVGGMLLI 607

Query: 173 QVIIAVEWLVLTVLRDTRPACAYEP 197
            + I + W  +  LR T    + EP
Sbjct: 608 DLCILICWQAVDPLRRTVEKYSMEP 632


>gi|112807234 G protein-coupled receptor, family C, group 6, member
           A [Homo sapiens]
          Length = 926

 Score = 38.5 bits (88), Expect = 0.011
 Identities = 45/211 (21%), Positives = 87/211 (41%), Gaps = 30/211 (14%)

Query: 68  LITLLLMLILLVRLPFIKEKEKKSPV-----GLH--FLFLLGTLGLFGLTFAFIIQEDET 120
           LI  LL +I ++ +  I  +   +PV     GL   ++ LL     F  T  FI +  + 
Sbjct: 598 LILSLLGIIFVLVVGIIFTRNLNTPVVKSSGGLRVCYVILLCHFLNFASTSFFIGEPQDF 657

Query: 121 ICSVRRFLWGVLFALCFSCLLSQAWRVRRLVRHGTGPAGWQLVGLALCLML--------- 171
            C  R+ ++GV F LC SC+L+++ ++  L+     P   +L     CL           
Sbjct: 658 TCKTRQTMFGVSFTLCISCILTKSLKI--LLAFSFDP---KLQKFLKCLYRPILIIFTCT 712

Query: 172 -VQVIIAVEWLVLTV----LRDTRPACAYEPMDFVMALIYDMVL---LVVTLGLALFTLC 223
            +QV+I   WL+       +  + P       +    L +  +L    ++     +F   
Sbjct: 713 GIQVVICTLWLIFAAPTVEVNVSLPRVIILECEEGSILAFGTMLGYIAILAFICFIFAFK 772

Query: 224 GKFKRWKLNGAFLLITAFLSVLIWVAWMTMY 254
           GK++ +     F+     +  + W+ ++ +Y
Sbjct: 773 GKYENYN-EAKFITFGMLIYFIAWITFIPIY 802


>gi|23308585 G protein-coupled receptor 156 [Homo sapiens]
          Length = 814

 Score = 37.0 bits (84), Expect = 0.032
 Identities = 68/323 (21%), Positives = 121/323 (37%), Gaps = 58/323 (17%)

Query: 71  LLLMLILLVRLPFIKEKE--KKSPVGLHFLFLLGTLGLFGLTFAFIIQED------ETIC 122
           LLL+L  L      ++    K S   L+ + LLG+   +   + F IQ+       ET+ 
Sbjct: 61  LLLILFFLAFTIHCRKNRIVKMSSPNLNIVTLLGSCLTYSSAYLFGIQDVLVGSSMETLI 120

Query: 123 SVRRFLWGVLFALCFSCLLSQAWRVRRLVRHGTGP-----AGWQLVGLALCLMLVQVIIA 177
             R  +  +  +L F  +L ++WR+ ++               QL+GL   L++  VI+ 
Sbjct: 121 QTRLSMLCIGTSLVFGPILGKSWRLYKVFTQRVPDKRVIIKDLQLLGLVAALLMADVILL 180

Query: 178 VEWLV--------------------LTVLRDTRPACAYEPMDFVMALIYDMVLLVVTLGL 217
           + W++                    ++    +   CA    D  +ALI+    L++  G 
Sbjct: 181 MTWVLTDPIQCLQILSVSMTVTGKDVSCTSTSTHFCASRYSDVWIALIWGCKGLLLLYGA 240

Query: 218 ALFTLCGKFKRWKLNGAFLLITAFLSVLIWVAWMTMYLFGNVKLQQGDAWNDPTLAITLA 277
            L  L G      +N + L I   +++L+  A +       V  +   +W  P L   L 
Sbjct: 241 YLAGLTGHVSSPPVNQS-LTIMVGVNLLVLAAGLLF-----VVTRYLHSW--PNLVFGLT 292

Query: 278 ASGWVFVIFHAIPEIHCTL-LPALQE------------NTPNYFDTSQPRMRETAFEEDV 324
           + G    IF     I+C + +P L++                YF T          EE+ 
Sbjct: 293 SGG----IFVCTTTINCFIFIPQLKQWKAFEEENQTIRRMAKYFSTPNKSFHTQYGEEEN 348

Query: 325 QLPRAYMENKAFSMDEHNAALRT 347
             PR    +    + E NA + +
Sbjct: 349 CHPRGEKSSMERLLTEKNAVIES 371


>gi|190341091 feline leukemia virus subgroup C cellular receptor
           family, member 2 [Homo sapiens]
          Length = 526

 Score = 30.8 bits (68), Expect = 2.3
 Identities = 19/73 (26%), Positives = 35/73 (47%), Gaps = 7/73 (9%)

Query: 117 EDETICSVRRFLWGVLFAL-CFSCLLSQAW----RVRRLVRHGTGPAGWQLVGLALCLML 171
           ED ++  V R  W V+    C+S   S  W     +  +  H  G + + +  L++C ML
Sbjct: 73  EDLSVIKVSRRRWAVVLVFSCYSMCNSFQWIQYGSINNIFMHFYGVSAFAIDWLSMCYML 132

Query: 172 --VQVIIAVEWLV 182
             + +++ V WL+
Sbjct: 133 TYIPLLLPVAWLL 145


>gi|150378545 POM121 membrane glycoprotein (rat)-like [Homo sapiens]
          Length = 987

 Score = 30.0 bits (66), Expect = 3.9
 Identities = 26/90 (28%), Positives = 34/90 (37%), Gaps = 3/90 (3%)

Query: 304 TPNYFDTSQPRMRETAFEEDVQLPRAYMENKAFSMDEHNAALRTAGFP-NGSLGKRPSGS 362
           +P  F  S       +F  +V  P +     AFS     +       P  G LG+   G+
Sbjct: 833 SPFTFGGSAAPAGSGSFGINVATPGSSATTGAFSFGAGQSGSTATSTPFTGGLGQNALGT 892

Query: 363 LGKRPSAPFRSNVYQPTEMAVVLNGGTIPT 392
            G+  S PF  NV   TE   V  G   PT
Sbjct: 893 TGQ--STPFAFNVGSTTESKPVFGGTATPT 920


>gi|153792776 G protein-coupled receptor 171 [Homo sapiens]
          Length = 319

 Score = 30.0 bits (66), Expect = 3.9
 Identities = 52/227 (22%), Positives = 96/227 (42%), Gaps = 39/227 (17%)

Query: 96  HFLFLLGTLGLFGLTFAFIIQEDETICSVRRFLWGVLFALCFSCLLSQAWRVRRLVRHGT 155
           + +FL+G +G    T+AFI +     C V  +L  +L A     LL+ A  V+ +V  G 
Sbjct: 22  YLVFLVGIIGSCFATWAFIQKNTNHRC-VSIYLINLLTA---DFLLTLALPVKIVVDLGV 77

Query: 156 GPAGWQL----VGLALCLMLVQVIIAVEWLVLT----VLRDTRPACAY---EP--MDFVM 202
            P  W+L      +  CL+ + + +++ +L        L+ T     Y   EP     + 
Sbjct: 78  AP--WKLKIFHCQVTACLIYINMYLSIIFLAFVSIDRCLQLTHSCKIYRIQEPGFAKMIS 135

Query: 203 ALIYDMVLLVVTLGLAL---------FTLCGKFKR-----WKLNGAFLLITAFLS----V 244
            +++ MVLL++   + +            C +FK+     W L   F+ +  FL+    +
Sbjct: 136 TVVWLMVLLIMVPNMMIPIKDIKEKSNVGCMEFKKEFGRNWHLLTNFICVAIFLNFSAII 195

Query: 245 LIWVAWMTMYLFGNVKLQQGDAWNDPTLAITLAASGWV--FVIFHAI 289
           LI    +   L+ N   +         + I L  +G++  FV +H +
Sbjct: 196 LISNCLVIRQLYRNKDNENYPNVKKALINILLVTTGYIICFVPYHIV 242


>gi|26051278 nuclear pore membrane protein 121 [Homo sapiens]
          Length = 984

 Score = 29.6 bits (65), Expect = 5.1
 Identities = 26/90 (28%), Positives = 34/90 (37%), Gaps = 3/90 (3%)

Query: 304 TPNYFDTSQPRMRETAFEEDVQLPRAYMENKAFSMDEHNAALRTAGFP-NGSLGKRPSGS 362
           +P  F  S       +F  +V  P +     AFS     +       P  G LG+   G+
Sbjct: 830 SPFTFGGSAAPAGSGSFGINVATPGSSTTTGAFSFGAGQSGSTATSTPFAGGLGQNALGT 889

Query: 363 LGKRPSAPFRSNVYQPTEMAVVLNGGTIPT 392
            G+  S PF  NV   TE   V  G   PT
Sbjct: 890 TGQ--STPFAFNVSSTTESKPVFGGTATPT 917


>gi|110556646 transmembrane protein 8B isoform a [Homo sapiens]
          Length = 472

 Score = 29.3 bits (64), Expect = 6.6
 Identities = 29/104 (27%), Positives = 46/104 (44%), Gaps = 21/104 (20%)

Query: 66  GALITLLLMLILLVRLPFIKEKEKKSPVGLHFLFLLGTLGLFGLTFAFIIQEDETICSVR 125
           G+L+++ + +I + RL          PV    L+LLG + L     +  +Q D      R
Sbjct: 301 GSLMSVWVTVIAMARL---------QPVVKQVLYLLGAMLL-----SMALQLD------R 340

Query: 126 RFLWGVLFALCFSC-LLSQAWRVRRLVRHGTGPAGWQLVGLALC 168
             LW +L    F+  +L+ AW VR + R    P  W+     LC
Sbjct: 341 HGLWNLLGPSLFALGILATAWTVRSVRRRHCYPPTWRRWLFYLC 384


>gi|110556642 transmembrane protein 8B isoform a [Homo sapiens]
          Length = 472

 Score = 29.3 bits (64), Expect = 6.6
 Identities = 29/104 (27%), Positives = 46/104 (44%), Gaps = 21/104 (20%)

Query: 66  GALITLLLMLILLVRLPFIKEKEKKSPVGLHFLFLLGTLGLFGLTFAFIIQEDETICSVR 125
           G+L+++ + +I + RL          PV    L+LLG + L     +  +Q D      R
Sbjct: 301 GSLMSVWVTVIAMARL---------QPVVKQVLYLLGAMLL-----SMALQLD------R 340

Query: 126 RFLWGVLFALCFSC-LLSQAWRVRRLVRHGTGPAGWQLVGLALC 168
             LW +L    F+  +L+ AW VR + R    P  W+     LC
Sbjct: 341 HGLWNLLGPSLFALGILATAWTVRSVRRRHCYPPTWRRWLFYLC 384


>gi|239743232 PREDICTED: hypothetical protein XP_002342775 [Homo
           sapiens]
          Length = 834

 Score = 29.3 bits (64), Expect = 6.6
 Identities = 26/90 (28%), Positives = 34/90 (37%), Gaps = 3/90 (3%)

Query: 304 TPNYFDTSQPRMRETAFEEDVQLPRAYMENKAFSMDEHNAALRTAGFP-NGSLGKRPSGS 362
           +P  F  S       +F  +V  P +     AFS     +       P  G LG+   G+
Sbjct: 680 SPFTFGGSAAPAGSGSFGINVATPGSSATTGAFSFGAGQSGSTATSTPFAGGLGQNALGT 739

Query: 363 LGKRPSAPFRSNVYQPTEMAVVLNGGTIPT 392
            G+  S PF  NV   TE   V  G   PT
Sbjct: 740 TGQ--STPFAFNVGSTTESKPVFGGTATPT 767


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.328    0.141    0.446 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,411,063
Number of Sequences: 37866
Number of extensions: 672853
Number of successful extensions: 1965
Number of sequences better than 10.0: 27
Number of HSP's better than 10.0 without gapping: 19
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 1927
Number of HSP's gapped (non-prelim): 28
length of query: 403
length of database: 18,247,518
effective HSP length: 105
effective length of query: 298
effective length of database: 14,271,588
effective search space: 4252933224
effective search space used: 4252933224
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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