Guide to the Human Genome
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Search of human proteins with 7705421

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|7705421 hydroxysteroid (17-beta) dehydrogenase 7 [Homo
sapiens]
         (341 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|7705421 hydroxysteroid (17-beta) dehydrogenase 7 [Homo sapiens]    680   0.0  
gi|7706523 WW domain-containing oxidoreductase isoform 1 [Homo s...    81   1e-15
gi|10190746 retinol dehydrogenase 14 (all-trans and 9-cis) [Homo...    77   3e-14
gi|225579078 retinol dehydrogenase 13 isoform 1 [Homo sapiens]         67   2e-11
gi|193804850 dehydrogenase/reductase (SDR family) X-linked [Homo...    65   9e-11
gi|166795268 retinol dehydrogenase 11 [Homo sapiens]                   62   1e-09
gi|186928839 retinol dehydrogenase 12 [Homo sapiens]                   59   5e-09
gi|20149619 dehydrogenase/reductase (SDR family) member 7B [Homo...    53   3e-07
gi|59889578 dehydrogenase/reductase (SDR family) member 10 [Homo...    47   2e-05
gi|19923931 retinol dehydrogenase 13 isoform 2 [Homo sapiens]          47   2e-05
gi|146231950 dehydrogenase/reductase (SDR family) member 13 [Hom...    43   5e-04
gi|223718074 hydroxysteroid (17-beta) dehydrogenase 1 [Homo sapi...    42   6e-04
gi|224922801 hydroxyprostaglandin dehydrogenase 15-(NAD) isoform...    42   6e-04
gi|31542939 hydroxyprostaglandin dehydrogenase 15-(NAD) isoform ...    42   6e-04
gi|4502599 carbonyl reductase 1 [Homo sapiens]                         42   8e-04
gi|7657478 retinol dehydrogenase 8 (all-trans) [Homo sapiens]          42   0.001
gi|18860884 WW domain-containing oxidoreductase isoform 2 [Homo ...    40   0.003
gi|4502601 carbonyl reductase 3 [Homo sapiens]                         38   0.011
gi|40548397 NADP-dependent retinol dehydrogenase/reductase [Homo...    38   0.011
gi|210032110 hydroxysteroid (17-beta) dehydrogenase 13 isoform A...    38   0.011
gi|214010158 NADP-dependent retinol dehydrogenase/reductase [Hom...    38   0.011
gi|214010156 NADP-dependent retinol dehydrogenase/reductase [Hom...    38   0.011
gi|22758144 NADP-dependent retinol dehydrogenase/reductase [Homo...    38   0.011
gi|7706318 dehydrogenase/reductase (SDR family) member 7 [Homo s...    37   0.019
gi|19923817 peroxisomal trans-2-enoyl-CoA reductase [Homo sapiens]     37   0.019
gi|4758504 hydroxysteroid (17-beta) dehydrogenase 10 isoform 1 [...    37   0.033
gi|150247226 retinol dehydrogenase 16 [Homo sapiens]                   37   0.033
gi|83715985 hydroxysteroid (17-beta) dehydrogenase 10 isoform 2 ...    36   0.043
gi|4504503 hydroxysteroid (17-beta) dehydrogenase 2 [Homo sapiens]     36   0.057
gi|109715829 short-chain dehydrogenase/reductase [Homo sapiens]        36   0.057

>gi|7705421 hydroxysteroid (17-beta) dehydrogenase 7 [Homo sapiens]
          Length = 341

 Score =  680 bits (1754), Expect = 0.0
 Identities = 341/341 (100%), Positives = 341/341 (100%)

Query: 1   MRKVVLITGASSGIGLALCKRLLAEDDELHLCLACRNMSKAEAVCAALLASHPTAEVTIV 60
           MRKVVLITGASSGIGLALCKRLLAEDDELHLCLACRNMSKAEAVCAALLASHPTAEVTIV
Sbjct: 1   MRKVVLITGASSGIGLALCKRLLAEDDELHLCLACRNMSKAEAVCAALLASHPTAEVTIV 60

Query: 61  QVDVSNLQSVFRASKELKQRFQRLDCIYLNAGIMPNPQLNIKALFFGLFSRKVIHMFSTA 120
           QVDVSNLQSVFRASKELKQRFQRLDCIYLNAGIMPNPQLNIKALFFGLFSRKVIHMFSTA
Sbjct: 61  QVDVSNLQSVFRASKELKQRFQRLDCIYLNAGIMPNPQLNIKALFFGLFSRKVIHMFSTA 120

Query: 121 EGLLTQGDKITADGLQEVFETNVFGHFILIRELEPLLCHSDNPSQLIWTSSRSARKSNFS 180
           EGLLTQGDKITADGLQEVFETNVFGHFILIRELEPLLCHSDNPSQLIWTSSRSARKSNFS
Sbjct: 121 EGLLTQGDKITADGLQEVFETNVFGHFILIRELEPLLCHSDNPSQLIWTSSRSARKSNFS 180

Query: 181 LEDFQHSKGKEPYSSSKYATDLLSVALNRNFNQQGLYSNVACPGTALTNLTYGILPPFIW 240
           LEDFQHSKGKEPYSSSKYATDLLSVALNRNFNQQGLYSNVACPGTALTNLTYGILPPFIW
Sbjct: 181 LEDFQHSKGKEPYSSSKYATDLLSVALNRNFNQQGLYSNVACPGTALTNLTYGILPPFIW 240

Query: 241 TLLMPAILLLRFFANAFTLTPYNGTEALVWLFHQKPESLNPLIKYLSATTGFGRNYIMTQ 300
           TLLMPAILLLRFFANAFTLTPYNGTEALVWLFHQKPESLNPLIKYLSATTGFGRNYIMTQ
Sbjct: 241 TLLMPAILLLRFFANAFTLTPYNGTEALVWLFHQKPESLNPLIKYLSATTGFGRNYIMTQ 300

Query: 301 KMDLDEDTAEKFYQKLLELEKHIRVTIQKTDNQARLSGSCL 341
           KMDLDEDTAEKFYQKLLELEKHIRVTIQKTDNQARLSGSCL
Sbjct: 301 KMDLDEDTAEKFYQKLLELEKHIRVTIQKTDNQARLSGSCL 341


>gi|7706523 WW domain-containing oxidoreductase isoform 1 [Homo
           sapiens]
          Length = 414

 Score = 81.3 bits (199), Expect = 1e-15
 Identities = 77/279 (27%), Positives = 116/279 (41%), Gaps = 53/279 (18%)

Query: 3   KVVLITGASSGIGLALCKRLLAEDDELHLCLACRNMSKAEAVCAALLASHPTAEVTIVQV 62
           KVV++TGA+SGIG    K         H+ LACRNM++A    + +L     A+V  + +
Sbjct: 125 KVVVVTGANSGIGFETAKSFALHG--AHVILACRNMARASEAVSRILEEWHKAKVEAMTL 182

Query: 63  DVSNLQSVFRASKELKQRFQRLDCIYLNAGIMPNPQLNIKALFFGLFSRKVIHMFSTAEG 122
           D++ L+SV   ++  K +   L  +  NA     P                         
Sbjct: 183 DLALLRSVQHFAEAFKAKNVPLHVLVCNAATFALPW------------------------ 218

Query: 123 LLTQGDKITADGLQEVFETNVFGHFILIRELEPLLCHSDNPSQLIWTSSRSARKS--NFS 180
                  +T DGL+  F+ N  GHF L++ L+ +LC S  P+++I  SS S R +  N S
Sbjct: 219 ------SLTKDGLETTFQVNHLGHFYLVQLLQDVLCRS-APARVIVVSSESHRFTDINDS 271

Query: 181 LEDFQHSK---------GKEPYSSSKYATDLLSVALNRNFNQQGLYSNVACPGTALTNLT 231
           L     S+             Y+ SK    L S  L+R  + +G+ SN   PG    N+ 
Sbjct: 272 LGKLDFSRLSPTKNDYWAMLAYNRSKLCNILFSNELHRRLSPRGVTSNAVHPG----NMM 327

Query: 232 YGILPPFIWTLLMPAILLLRFFANAFTLTPYNGTEALVW 270
           Y  +    W        LL   A  FT +   G    V+
Sbjct: 328 YSNIHRSWW-----VYTLLFTLARPFTKSMQQGAATTVY 361


>gi|10190746 retinol dehydrogenase 14 (all-trans and 9-cis) [Homo
           sapiens]
          Length = 336

 Score = 76.6 bits (187), Expect = 3e-14
 Identities = 78/285 (27%), Positives = 116/285 (40%), Gaps = 55/285 (19%)

Query: 3   KVVLITGASSGIGLALCKRLLAEDDELHLCLACRNMSKAE-------------AVCAALL 49
           K VLITGA+SG+G A    LL       + + CR+ ++AE             A C    
Sbjct: 44  KTVLITGANSGLGRATAAELLRLG--ARVIMGCRDRARAEEAAGQLRRELRQAAECGPEP 101

Query: 50  ASHPTAEVTIVQVDVSNLQSVFRASKELKQRFQRLDCIYLNAGIMPNPQLNIKALFFGLF 109
                 E+ + ++D+++L+SV    +E+ Q   RLD +  NAGI   P +          
Sbjct: 102 GVSGVGELIVRELDLASLRSVRAFCQEMLQEEPRLDVLINNAGIFQCPYMK--------- 152

Query: 110 SRKVIHMFSTAEGLLTQGDKITADGLQEVFETNVFGHFILIRELEPLLCHSDNPSQLIWT 169
                                T DG +  F  N  GHF+L   L  LL  S  PS+++  
Sbjct: 153 ---------------------TEDGFEMQFGVNHLGHFLLTNLLLGLL-KSSAPSRIVVV 190

Query: 170 SSRSARKSNFSLEDFQHSKGKEP---YSSSKYATDLLSVALNRNFNQQGLYSNVACPGTA 226
           SS+  +  + + +D    +       YS SK A  L +  L R      +  NV  PG  
Sbjct: 191 SSKLYKYGDINFDDLNSEQSYNKSFCYSRSKLANILFTRELARRLEGTNVTVNVLHPGIV 250

Query: 227 LTNLTYGILPPFIWTLLMPAILLLRFFANAFTLTPYNGTEALVWL 271
            TNL   I  P    L+ P   L+ +   AF  TP  G +  ++L
Sbjct: 251 RTNLGRHIHIPL---LVKPLFNLVSW---AFFKTPVEGAQTSIYL 289


>gi|225579078 retinol dehydrogenase 13 isoform 1 [Homo sapiens]
          Length = 331

 Score = 67.4 bits (163), Expect = 2e-11
 Identities = 60/232 (25%), Positives = 94/232 (40%), Gaps = 37/232 (15%)

Query: 3   KVVLITGASSGIGLALCKRLLAEDDELHLCLACRNMSKAEAVCAALLASHPTAEVTIVQV 62
           K V++TGA++GIG      L       ++ LACR+M K EA    +        V    +
Sbjct: 39  KTVIVTGANTGIGKQTALELARRGG--NIILACRDMEKCEAAAKDIRGETLNHHVNARHL 96

Query: 63  DVSNLQSVFRASKELKQRFQRLDCIYLNAGIMPNPQLNIKALFFGLFSRKVIHMFSTAEG 122
           D+++L+S+   + ++ +  +R+D +  NAG+M  P                         
Sbjct: 97  DLASLKSIREFAAKIIEEEERVDILINNAGVMRCPHWT---------------------- 134

Query: 123 LLTQGDKITADGLQEVFETNVFGHFILIRELEPLLCHSDNPSQLIWTSSRSARKSNFSLE 182
                   T DG +  F  N  GHF+L   L   L  +  PS++I  SS +    +   +
Sbjct: 135 --------TEDGFEMQFGVNHLGHFLLTNLLLDKL-KASAPSRIINLSSLAHVAGHIDFD 185

Query: 183 DF----QHSKGKEPYSSSKYATDLLSVALNRNFNQQGLYSNVACPGTALTNL 230
           D     +    K  Y  SK A  L +  L+R     G+  N   PG A T L
Sbjct: 186 DLNWQTRKYNTKAAYCQSKLAIVLFTKELSRRLQGSGVTVNALHPGVARTEL 237


>gi|193804850 dehydrogenase/reductase (SDR family) X-linked [Homo
           sapiens]
          Length = 330

 Score = 65.1 bits (157), Expect = 9e-11
 Identities = 59/236 (25%), Positives = 103/236 (43%), Gaps = 40/236 (16%)

Query: 3   KVVLITGASSGIGLALCKRLLAEDDELHLCLACRNMSKAEAVCAALLASHPTAEVTIVQV 62
           +V ++TG + GIG +  K L      +H+ +A  N SKA+ V + +       +V  +  
Sbjct: 44  RVAIVTGGTDGIGYSTAKHLARLG--MHVIIAGNNDSKAKQVVSKIKEETLNDKVEFLYC 101

Query: 63  DVSNLQSVFRASKELKQRFQRLDCIYLNAGIMPNPQLNIKALFFGLFSRKVIHMFSTAEG 122
           D++++ S+ +  ++ K +   L  +  NAG+M  PQ                        
Sbjct: 102 DLASMTSIRQFVQKFKMKKIPLHVLINNAGVMMVPQ------------------------ 137

Query: 123 LLTQGDKITADGLQEVFETNVFGHFILIRELEPLLCHSDNP---SQLIWTSSRSARKSNF 179
                 + T DG +E F  N  GHF+L   L   L  S +P   ++++  SS +   +  
Sbjct: 138 ------RKTRDGFEEHFGLNYLGHFLLTNLLLDTLKESGSPGHSARVVTVSSATHYVAEL 191

Query: 180 SLEDFQHSKGKEP---YSSSKYATDLLSVALNRNFNQQGLY--SNVACPGTALTNL 230
           +++D Q S    P   Y+ SK A  L +  L R    +G +  +NV  PG   T++
Sbjct: 192 NMDDLQSSACYSPHAAYAQSKLALVLFTYHLQRLLAAEGSHVTANVVDPGVVNTDV 247


>gi|166795268 retinol dehydrogenase 11 [Homo sapiens]
          Length = 318

 Score = 61.6 bits (148), Expect = 1e-09
 Identities = 60/231 (25%), Positives = 95/231 (41%), Gaps = 36/231 (15%)

Query: 3   KVVLITGASSGIGLALCKRLLAEDDELHLCLACRNMSKAEAVCAALLASHPTAEVTIVQV 62
           KVV++TGA++GIG    K L      ++L  ACR++ K E V   +  +    +V + ++
Sbjct: 42  KVVVVTGANTGIGKETAKELAQRGARVYL--ACRDVEKGELVAKEIQTTTGNQQVLVRKL 99

Query: 63  DVSNLQSVFRASKELKQRFQRLDCIYLNAGIMPNPQLNIKALFFGLFSRKVIHMFSTAEG 122
           D+S+ +S+   +K      + L  +  NAG+M  P           +S+           
Sbjct: 100 DLSDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCP-----------YSK----------- 137

Query: 123 LLTQGDKITADGLQEVFETNVFGHFILIRELEPLLCHSDNPSQLIWTSSRSARKSNFSLE 182
                   TADG +     N  GHF+L   L   L  S  PS+++  SS +         
Sbjct: 138 --------TADGFEMHIGVNHLGHFLLTHLLLEKLKES-APSRIVNVSSLAHHLGRIHFH 188

Query: 183 DFQHSK---GKEPYSSSKYATDLLSVALNRNFNQQGLYSNVACPGTALTNL 230
           + Q  K       Y  SK A  L +  L R     G+ +    PGT  + L
Sbjct: 189 NLQGEKFYNAGLAYCHSKLANILFTQELARRLKGSGVTTYSVHPGTVQSEL 239


>gi|186928839 retinol dehydrogenase 12 [Homo sapiens]
          Length = 316

 Score = 59.3 bits (142), Expect = 5e-09
 Identities = 60/253 (23%), Positives = 105/253 (41%), Gaps = 37/253 (14%)

Query: 3   KVVLITGASSGIGLALCKRLLAEDDELHLCLACRNMSKAEAVCAALLASHPTAEVTIVQV 62
           KVV+ITGA++GIG    + L +    +++  ACR++ K E+  + +      ++V + ++
Sbjct: 40  KVVVITGANTGIGKETARELASRGARVYI--ACRDVLKGESAASEIRVDTKNSQVLVRKL 97

Query: 63  DVSNLQSVFRASKELKQRFQRLDCIYLNAGIMPNPQLNIKALFFGLFSRKVIHMFSTAEG 122
           D+S+ +S+   ++      ++L  +  NAG+M  P           +S+           
Sbjct: 98  DLSDTKSIRAFAEGFLAEEKQLHILINNAGVMMCP-----------YSK----------- 135

Query: 123 LLTQGDKITADGLQEVFETNVFGHFILIRELEPLLCHSDNPSQLIWTSSRSARKSNFSLE 182
                   TADG +     N  GHF+L   L   L  S  P++++  SS +         
Sbjct: 136 --------TADGFETHLGVNHLGHFLLTYLLLERLKVS-APARVVNVSSVAHHIGKIPFH 186

Query: 183 DFQHSKGKE---PYSSSKYATDLLSVALNRNFNQQGLYSNVACPGTALTNLT-YGILPPF 238
           D Q  K       Y  SK A  L +  L +     G+ +    PG   + L  +  L   
Sbjct: 187 DLQSEKRYSRGFAYCHSKLANVLFTRELAKRLQGTGVTTYAVHPGVVRSELVRHSSLLCL 246

Query: 239 IWTLLMPAILLLR 251
           +W L  P +   R
Sbjct: 247 LWRLFSPFVKTAR 259


>gi|20149619 dehydrogenase/reductase (SDR family) member 7B [Homo
           sapiens]
          Length = 325

 Score = 53.1 bits (126), Expect = 3e-07
 Identities = 62/232 (26%), Positives = 91/232 (39%), Gaps = 44/232 (18%)

Query: 4   VVLITGASSGIGLALCKRLLAEDDELHLCLACRNMSKAEAVCAALLASHPTAEVT----I 59
           VV+ITGA+SG+G    K   A   +L LC   RN    E +   L ASH T   T    +
Sbjct: 54  VVVITGATSGLGKECAKVFYAAGAKLVLC--GRNGGALEELIRELTASHATKVQTHKPYL 111

Query: 60  VQVDVSNLQSVFRASKELKQRFQRLDCIYLNAGIMPNPQLNIKALFFGLFSRKVIHMFST 119
           V  D+++  ++  A+ E+ Q F  +D +  NAGI                         +
Sbjct: 112 VTFDLTDSGAIVAAAAEILQCFGYVDILVNNAGI-------------------------S 146

Query: 120 AEGLLTQGDKITADGLQEVFETNVFGHFILIRELEPLLCHSDNPSQLIWTSSRSARKSNF 179
             G +      T D  + V ETN FG   L + L P +        ++  SS   + S  
Sbjct: 147 YRGTIMD---TTVDVDKRVMETNYFGPVALTKALLPSMI-KRRQGHIVAISSIQGKMS-- 200

Query: 180 SLEDFQHSKGKEPYSSSKYATDLLSVALNRNFNQQGLYSNVACPGTALTNLT 231
                     +  Y++SK+AT      L     Q  +   V  PG   TNL+
Sbjct: 201 -------IPFRSAYAASKHATQAFFDCLRAEMEQYEIEVTVISPGYIHTNLS 245


>gi|59889578 dehydrogenase/reductase (SDR family) member 10 [Homo
           sapiens]
          Length = 270

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 55/232 (23%), Positives = 87/232 (37%), Gaps = 54/232 (23%)

Query: 3   KVVLITGASSGIGLALCKRLLAEDDELHLCLACRNMSKAEAVCAALLASHPTAEVTIVQV 62
           KVV++TG   GIG  + +  +     + +C       K E+   AL    P A    +  
Sbjct: 10  KVVVVTGGGRGIGAGIVRAFVNSGARVVIC------DKDESGGRALEQELPGA--VFILC 61

Query: 63  DVSNLQSVFRASKELKQRFQRLDCIYLNAGIMPNPQLNIKALFFGLFSRKVIHMFSTAEG 122
           DV+    V     E  +RF RLDC+  NAG  P PQ                        
Sbjct: 62  DVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQ------------------------ 97

Query: 123 LLTQGDKITADGLQEVFETNVFGHFILIRELEPLLCHSD----NPSQLIWTSSRSARKSN 178
              + ++ +A G +++ E N+ G + L +   P L  S     N S L+    ++     
Sbjct: 98  ---RPEETSAQGFRQLLELNLLGTYTLTKLALPYLRKSQGNVINISSLVGAIGQAQ---- 150

Query: 179 FSLEDFQHSKGKEPYSSSKYATDLLSVALNRNFNQQGLYSNVACPGTALTNL 230
                        PY ++K A   ++ AL  + +  G+  N   PG   T L
Sbjct: 151 -----------AVPYVATKGAVTAMTKALALDESPYGVRVNCISPGNIWTPL 191


>gi|19923931 retinol dehydrogenase 13 isoform 2 [Homo sapiens]
          Length = 260

 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 47/197 (23%), Positives = 74/197 (37%), Gaps = 35/197 (17%)

Query: 38  MSKAEAVCAALLASHPTAEVTIVQVDVSNLQSVFRASKELKQRFQRLDCIYLNAGIMPNP 97
           M K EA    +        V    +D+++L+S+   + ++ +  +R+D +  NAG+M  P
Sbjct: 1   MEKCEAAAKDIRGETLNHHVNARHLDLASLKSIREFAAKIIEEEERVDILINNAGVMRCP 60

Query: 98  QLNIKALFFGLFSRKVIHMFSTAEGLLTQGDKITADGLQEVFETNVFGHFILIRELEPLL 157
                                            T DG +  F  N  GHF+L   L   L
Sbjct: 61  HWT------------------------------TEDGFEMQFGVNHLGHFLLTNLLLDKL 90

Query: 158 CHSDNPSQLIWTSSRSARKSNFSLEDF----QHSKGKEPYSSSKYATDLLSVALNRNFNQ 213
             +  PS++I  SS +    +   +D     +    K  Y  SK A  L +  L+R    
Sbjct: 91  -KASAPSRIINLSSLAHVAGHIDFDDLNWQTRKYNTKAAYCQSKLAIVLFTKELSRRLQG 149

Query: 214 QGLYSNVACPGTALTNL 230
            G+  N   PG A T L
Sbjct: 150 SGVTVNALHPGVARTEL 166


>gi|146231950 dehydrogenase/reductase (SDR family) member 13 [Homo
           sapiens]
          Length = 377

 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 57/255 (22%), Positives = 93/255 (36%), Gaps = 41/255 (16%)

Query: 3   KVVLITGASSGIGLALCKRLLAEDDELHLCLACRNMSKAEAVCAALLASHPTAEVTIVQV 62
           +  ++TGA+SGIG      L        + LACR+  + EA    L       EV  + +
Sbjct: 37  RTAVVTGANSGIGKMTALELARRG--ARVVLACRSQERGEAAAFDLRQESGNNEVIFMAL 94

Query: 63  DVSNLQSVFRASKELKQRFQRLDCIYLNAGIMPNPQLNIKALFFGLFSRKVIHMFSTAEG 122
           D+++L SV   +        RLD +  NAGI    +                        
Sbjct: 95  DLASLASVRAFATAFLSSEPRLDILIHNAGISSCGR------------------------ 130

Query: 123 LLTQGDKITADGLQEVFETNVFGHFILIRELEPLLCHSDNPSQLIWTSSRSARKSNFSLE 182
                   T +    +   N  G F+L   L P L  +  PS+++  +S +  +     +
Sbjct: 131 --------TREAFNLLLRVNHIGPFLLTHLLLPCL-KACAPSRVVVVASAAHCRGRLDFK 181

Query: 183 DFQH-----SKGKEPYSSSKYATDLLSVALNRNFNQQGLYSNVACPGTALTNLTYGILPP 237
                     +    Y+ +K A  L +  L       G+    A PG   + L    +P 
Sbjct: 182 RLDRPVVGWRQELRAYADTKLANVLFARELANQLEATGVTCYAAHPGPVNSELFLRHVPG 241

Query: 238 FIWTLLMP-AILLLR 251
           ++  LL P A L+LR
Sbjct: 242 WLRPLLRPLAWLVLR 256


>gi|223718074 hydroxysteroid (17-beta) dehydrogenase 1 [Homo
          sapiens]
          Length = 328

 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 32/94 (34%), Positives = 48/94 (51%), Gaps = 4/94 (4%)

Query: 2  RKVVLITGASSGIGLALCKRLLAEDDELHLCLACRNMSKAEAVC--AALLASHPTAEVTI 59
          R VVLITG SSGIGL L  RL ++  +     A     K +     AA   + P   +  
Sbjct: 3  RTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLET 62

Query: 60 VQVDVSNLQSVFRASKELKQRFQRLDCIYLNAGI 93
          +Q+DV + +SV  A + + +   R+D +  NAG+
Sbjct: 63 LQLDVRDSKSVAAARERVTE--GRVDVLVCNAGL 94


>gi|224922801 hydroxyprostaglandin dehydrogenase 15-(NAD) isoform
          2 [Homo sapiens]
          Length = 178

 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 28/91 (30%), Positives = 45/91 (49%), Gaps = 2/91 (2%)

Query: 3  KVVLITGASSGIGLALCKRLLAEDDELHLCLACRNMSKAEAVCAALLASHPTAEVTIVQV 62
          KV L+TGA+ GIG A  + LL +  +  + L   N+       AAL       +   +Q 
Sbjct: 6  KVALVTGAAQGIGRAFAEALLLKGAK--VALVDWNLEAGVQCKAALDEQFEPQKTLFIQC 63

Query: 63 DVSNLQSVFRASKELKQRFQRLDCIYLNAGI 93
          DV++ Q +    +++   F RLD +  NAG+
Sbjct: 64 DVADQQQLRDTFRKVVDHFGRLDILVNNAGV 94


>gi|31542939 hydroxyprostaglandin dehydrogenase 15-(NAD) isoform 1
          [Homo sapiens]
          Length = 266

 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 28/91 (30%), Positives = 45/91 (49%), Gaps = 2/91 (2%)

Query: 3  KVVLITGASSGIGLALCKRLLAEDDELHLCLACRNMSKAEAVCAALLASHPTAEVTIVQV 62
          KV L+TGA+ GIG A  + LL +  +  + L   N+       AAL       +   +Q 
Sbjct: 6  KVALVTGAAQGIGRAFAEALLLKGAK--VALVDWNLEAGVQCKAALDEQFEPQKTLFIQC 63

Query: 63 DVSNLQSVFRASKELKQRFQRLDCIYLNAGI 93
          DV++ Q +    +++   F RLD +  NAG+
Sbjct: 64 DVADQQQLRDTFRKVVDHFGRLDILVNNAGV 94


>gi|4502599 carbonyl reductase 1 [Homo sapiens]
          Length = 277

 Score = 42.0 bits (97), Expect = 8e-04
 Identities = 35/117 (29%), Positives = 58/117 (49%), Gaps = 19/117 (16%)

Query: 4   VVLITGASSGIGLALCK---RLLAEDDELHLCLACRNMSKAEAVCAALLASHPTAEVTIV 60
           V L+TG + GIGLA+ +   RL + D    + L  R++++ +A    L A   +      
Sbjct: 7   VALVTGGNKGIGLAIVRDLCRLFSGD----VVLTARDVTRGQAAVQQLQAEGLSPRFH-- 60

Query: 61  QVDVSNLQSVFRASKELKQRFQRLDCIYLNAGIM-----PNP-----QLNIKALFFG 107
           Q+D+ +LQS+      L++ +  LD +  NAGI      P P     ++ +K  FFG
Sbjct: 61  QLDIDDLQSIRALRDFLRKEYGGLDVLVNNAGIAFKVADPTPFHIQAEVTMKTNFFG 117


>gi|7657478 retinol dehydrogenase 8 (all-trans) [Homo sapiens]
          Length = 311

 Score = 41.6 bits (96), Expect = 0.001
 Identities = 52/228 (22%), Positives = 97/228 (42%), Gaps = 45/228 (19%)

Query: 3   KVVLITGASSGIGLALCKRLLAEDDELHLCLA-CRNMSKAEAVCAALLASHPTAE-VTIV 60
           + VLI+G SSGIGL L  +L  +  + +  +A  R++ K E + AA  A     + +T+ 
Sbjct: 6   RTVLISGCSSGIGLELAVQLAHDPKKRYQVVATMRDLGKKETLEAA--AGEALGQTLTVA 63

Query: 61  QVDVSNLQSVFRASKELKQRFQRLDCIYLNAGIMPNPQLNIKALFFGLFSRKVIHMFSTA 120
           Q+DV + +SV           Q L CI     ++ N                     +  
Sbjct: 64  QLDVCSDESV----------AQCLSCIQGEVDVLVN---------------------NAG 92

Query: 121 EGLLTQGDKITADGLQEVFETNVFGHFILIRELEPLLCHSDNPSQLIWTSSRSARKSNFS 180
            GL+   + ++   +Q VF+TN FG   L++ + P +        ++ +S    +   F+
Sbjct: 93  MGLVGPLEGLSLAAMQNVFDTNFFGAVRLVKAVLPGMKRRRQGHIVVISSVMGLQGVIFN 152

Query: 181 LEDFQHSKGKEPYSSSKYATDLLSVALNRNFNQQGLYSNVACPGTALT 228
                     + Y++SK+A +    +L     Q  ++ ++  PG  +T
Sbjct: 153 ----------DVYAASKFALEGFFESLAIQLLQFNIFISLVEPGPVVT 190


>gi|18860884 WW domain-containing oxidoreductase isoform 2 [Homo
           sapiens]
          Length = 189

 Score = 40.0 bits (92), Expect = 0.003
 Identities = 23/65 (35%), Positives = 34/65 (52%), Gaps = 7/65 (10%)

Query: 3   KVVLITGASSGIGLALCKRLLAEDDELHLCLACRNMSKAEAVCAALLAS-----HPTAEV 57
           KVV++TGA+SGIG    K         H+ LACRNM++A    + +L       HP  E 
Sbjct: 125 KVVVVTGANSGIGFETAKSFALHG--AHVILACRNMARASEAVSRILEEWKTKYHPPPEK 182

Query: 58  TIVQV 62
             +++
Sbjct: 183 CRIKI 187


>gi|4502601 carbonyl reductase 3 [Homo sapiens]
          Length = 277

 Score = 38.1 bits (87), Expect = 0.011
 Identities = 25/91 (27%), Positives = 48/91 (52%), Gaps = 3/91 (3%)

Query: 3  KVVLITGASSGIGLALCKRLLAEDDELHLCLACRNMSKAEAVCAALLASHPTAEVTIVQV 62
          +V L+TGA+ GIGLA+ + L  +     + L  R++++ +A    L A   +      Q+
Sbjct: 6  RVALVTGANRGIGLAIARELCRQFSG-DVVLTARDVARGQAAVQQLQAEGLSPR--FHQL 62

Query: 63 DVSNLQSVFRASKELKQRFQRLDCIYLNAGI 93
          D+ +LQS+      L++ +  L+ +  NA +
Sbjct: 63 DIDDLQSIRALRDFLRKEYGGLNVLVNNAAV 93


>gi|40548397 NADP-dependent retinol dehydrogenase/reductase [Homo
           sapiens]
          Length = 319

 Score = 38.1 bits (87), Expect = 0.011
 Identities = 52/228 (22%), Positives = 92/228 (40%), Gaps = 44/228 (19%)

Query: 3   KVVLITGASSGIGLALCKRLLAEDDELHLCLACRNMSKAEAVCAALLASHPTAEVTIVQV 62
           K + ITG  SG G    +    +    H+  AC   S + A     L +  +  +  V +
Sbjct: 30  KYIFITGCDSGFGNLAARTF--DKKGFHVIAACLTESGSTA-----LKAETSERLRTVLL 82

Query: 63  DVSNLQSVFRASKELKQRFQRLDCIYLNAGIMPNPQLNIKALFFGLFSRKVIHMFSTAEG 122
           DV++ ++V R ++ +K                   Q+  K L+ GL +   +       G
Sbjct: 83  DVTDPENVKRTAQWVKN------------------QVGEKGLW-GLINNAGV------PG 117

Query: 123 LLTQGDKITADGLQEVFETNVFGHFILIRELEPLLCHSDNPSQLIWTSSRSARKSNFSLE 182
           +L   D +T +  +E  E N+FG   +   + PL+  +    ++I  SS   R +     
Sbjct: 118 VLAPTDWLTLEDYREPIEVNLFGLISVTLNMLPLVKKAQG--RVINVSSVGGRLAIVG-- 173

Query: 183 DFQHSKGKEPYSSSKYATDLLSVALNRNFNQQGLYSNVACPGTALTNL 230
                     Y+ SKYA +  + +L R+    G++ +   PG   TNL
Sbjct: 174 --------GGYTPSKYAVEGFNDSLRRDMKAFGVHVSCIEPGLFKTNL 213


>gi|210032110 hydroxysteroid (17-beta) dehydrogenase 13 isoform A
           [Homo sapiens]
          Length = 300

 Score = 38.1 bits (87), Expect = 0.011
 Identities = 55/237 (23%), Positives = 91/237 (38%), Gaps = 55/237 (23%)

Query: 3   KVVLITGASSGIGLALCKRLLAEDDELHLC-LACRNMSKAEAVCAALLASHPTAEVTIVQ 61
           ++VLITGA  GIG             L L  +  R + +  A C  L     TA   +V 
Sbjct: 37  EIVLITGAGHGIGRQTTYEFAKRQSILVLWDINKRGVEETAAECRKLGV---TAHAYVV- 92

Query: 62  VDVSNLQSVFRASKELKQRFQRLDCIYLNAGIMPNPQLNIKALFFGLFSRKVIHMFSTAE 121
            D SN + ++R+  ++K+    +  +  NAG +                         A+
Sbjct: 93  -DCSNREEIYRSLNQVKKEVGDVTIVVNNAGTV-----------------------YPAD 128

Query: 122 GLLTQGDKITADGLQEVFETNVFGHFILIRELEPLLCHSDNPSQLIWTSSRSARKSNFSL 181
            L T+ ++IT     + FE N+ GHF + + L P +    N   ++  +S    +    L
Sbjct: 129 LLSTKDEEIT-----KTFEVNILGHFWITKALLPSMMER-NHGHIVTVASVCGHEGIPYL 182

Query: 182 EDFQHSKGKEPYSSSKYATDLLSVALNRNFNQQ-------GLYSNVACPGTALTNLT 231
                     PY SSK+A    +V  +R    +       G+ ++  CP    T  T
Sbjct: 183 ---------IPYCSSKFA----AVGFHRGLTSELQALGKTGIKTSCLCPVFVNTGFT 226


>gi|214010158 NADP-dependent retinol dehydrogenase/reductase [Homo
           sapiens]
          Length = 319

 Score = 38.1 bits (87), Expect = 0.011
 Identities = 52/228 (22%), Positives = 92/228 (40%), Gaps = 44/228 (19%)

Query: 3   KVVLITGASSGIGLALCKRLLAEDDELHLCLACRNMSKAEAVCAALLASHPTAEVTIVQV 62
           K + ITG  SG G    +    +    H+  AC   S + A     L +  +  +  V +
Sbjct: 30  KYIFITGCDSGFGNLAARTF--DKKGFHVIAACLTESGSTA-----LKAETSERLRTVLL 82

Query: 63  DVSNLQSVFRASKELKQRFQRLDCIYLNAGIMPNPQLNIKALFFGLFSRKVIHMFSTAEG 122
           DV++ ++V R ++ +K                   Q+  K L+ GL +   +       G
Sbjct: 83  DVTDPENVKRTAQWVKN------------------QVGEKGLW-GLINNAGV------PG 117

Query: 123 LLTQGDKITADGLQEVFETNVFGHFILIRELEPLLCHSDNPSQLIWTSSRSARKSNFSLE 182
           +L   D +T +  +E  E N+FG   +   + PL+  +    ++I  SS   R +     
Sbjct: 118 VLAPTDWLTLEDYREPIEVNLFGLISVTLNMLPLVKKAQG--RVINVSSVGGRLAIVG-- 173

Query: 183 DFQHSKGKEPYSSSKYATDLLSVALNRNFNQQGLYSNVACPGTALTNL 230
                     Y+ SKYA +  + +L R+    G++ +   PG   TNL
Sbjct: 174 --------GGYTPSKYAVEGFNDSLRRDMKAFGVHVSCIEPGLFKTNL 213


>gi|214010156 NADP-dependent retinol dehydrogenase/reductase [Homo
           sapiens]
          Length = 319

 Score = 38.1 bits (87), Expect = 0.011
 Identities = 52/228 (22%), Positives = 92/228 (40%), Gaps = 44/228 (19%)

Query: 3   KVVLITGASSGIGLALCKRLLAEDDELHLCLACRNMSKAEAVCAALLASHPTAEVTIVQV 62
           K + ITG  SG G    +    +    H+  AC   S + A     L +  +  +  V +
Sbjct: 30  KYIFITGCDSGFGNLAARTF--DKKGFHVIAACLTESGSTA-----LKAETSERLRTVLL 82

Query: 63  DVSNLQSVFRASKELKQRFQRLDCIYLNAGIMPNPQLNIKALFFGLFSRKVIHMFSTAEG 122
           DV++ ++V R ++ +K                   Q+  K L+ GL +   +       G
Sbjct: 83  DVTDPENVKRTAQWVKN------------------QVGEKGLW-GLINNAGV------PG 117

Query: 123 LLTQGDKITADGLQEVFETNVFGHFILIRELEPLLCHSDNPSQLIWTSSRSARKSNFSLE 182
           +L   D +T +  +E  E N+FG   +   + PL+  +    ++I  SS   R +     
Sbjct: 118 VLAPTDWLTLEDYREPIEVNLFGLISVTLNMLPLVKKAQG--RVINVSSVGGRLAIVG-- 173

Query: 183 DFQHSKGKEPYSSSKYATDLLSVALNRNFNQQGLYSNVACPGTALTNL 230
                     Y+ SKYA +  + +L R+    G++ +   PG   TNL
Sbjct: 174 --------GGYTPSKYAVEGFNDSLRRDMKAFGVHVSCIEPGLFKTNL 213


>gi|22758144 NADP-dependent retinol dehydrogenase/reductase [Homo
           sapiens]
          Length = 319

 Score = 38.1 bits (87), Expect = 0.011
 Identities = 52/228 (22%), Positives = 92/228 (40%), Gaps = 44/228 (19%)

Query: 3   KVVLITGASSGIGLALCKRLLAEDDELHLCLACRNMSKAEAVCAALLASHPTAEVTIVQV 62
           K + ITG  SG G    +    +    H+  AC   S + A     L +  +  +  V +
Sbjct: 30  KYIFITGCDSGFGNLAARTF--DKKGFHVIAACLTESGSTA-----LKAETSERLRTVLL 82

Query: 63  DVSNLQSVFRASKELKQRFQRLDCIYLNAGIMPNPQLNIKALFFGLFSRKVIHMFSTAEG 122
           DV++ ++V R ++ +K                   Q+  K L+ GL +   +       G
Sbjct: 83  DVTDPENVKRTAQWVKN------------------QVGEKGLW-GLINNAGV------PG 117

Query: 123 LLTQGDKITADGLQEVFETNVFGHFILIRELEPLLCHSDNPSQLIWTSSRSARKSNFSLE 182
           +L   D +T +  +E  E N+FG   +   + PL+  +    ++I  SS   R +     
Sbjct: 118 VLAPTDWLTLEDYREPIEVNLFGLISVTLNMLPLVKKAQG--RVINVSSVGGRLAIVG-- 173

Query: 183 DFQHSKGKEPYSSSKYATDLLSVALNRNFNQQGLYSNVACPGTALTNL 230
                     Y+ SKYA +  + +L R+    G++ +   PG   TNL
Sbjct: 174 --------GGYTPSKYAVEGFNDSLRRDMKAFGVHVSCIEPGLFKTNL 213


>gi|7706318 dehydrogenase/reductase (SDR family) member 7 [Homo
           sapiens]
          Length = 339

 Score = 37.4 bits (85), Expect = 0.019
 Identities = 29/92 (31%), Positives = 48/92 (52%), Gaps = 4/92 (4%)

Query: 4   VVLITGASSGIGLALCKRLLAEDDELHLCLACRNMSKAEAVCAALLASHPTAE--VTIVQ 61
           VV +TGASSGIG  L  +L      + L L+ R + + E V    L +    E  + ++ 
Sbjct: 52  VVWVTGASSGIGEELAYQL--SKLGVSLVLSARRVHELERVKRRCLENGNLKEKDILVLP 109

Query: 62  VDVSNLQSVFRASKELKQRFQRLDCIYLNAGI 93
           +D+++  S   A+K + Q F R+D +  N G+
Sbjct: 110 LDLTDTGSHEAATKAVLQEFGRIDILVNNGGM 141


>gi|19923817 peroxisomal trans-2-enoyl-CoA reductase [Homo sapiens]
          Length = 303

 Score = 37.4 bits (85), Expect = 0.019
 Identities = 35/152 (23%), Positives = 64/152 (42%), Gaps = 33/152 (21%)

Query: 3   KVVLITGASSGIGLALCKRLLAEDDELHLCLACRNMSKAEAVCAALLASHP---TAEVTI 59
           +V ++TG ++GIG A+ K LL      ++ +A R + + ++    L A+ P    A V  
Sbjct: 19  QVAIVTGGATGIGKAIVKELLELGS--NVVIASRKLERLKSAADELQANLPPTKQARVIP 76

Query: 60  VQVDVSNLQSVFRASKELKQRFQRLDCIYLNAGIMPNPQLNIKALFFGLFSRKVIHMFST 119
           +Q ++ N + V    K     F +++ +  N G              G F          
Sbjct: 77  IQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGG--------------GQF---------- 112

Query: 120 AEGLLTQGDKITADGLQEVFETNVFGHFILIR 151
               L+  + I++ G   V ETN+ G F + +
Sbjct: 113 ----LSPAEHISSKGWHAVLETNLTGTFYMCK 140


>gi|4758504 hydroxysteroid (17-beta) dehydrogenase 10 isoform 1
           [Homo sapiens]
          Length = 261

 Score = 36.6 bits (83), Expect = 0.033
 Identities = 50/222 (22%), Positives = 87/222 (39%), Gaps = 35/222 (15%)

Query: 4   VVLITGASSGIGLALCKRLLAEDDELHLCLACRNMSKAEAVCAALLASHPTAEVTIVQVD 63
           V +ITG +SG+GLA  +RL+ +     L     +  +A+       A            D
Sbjct: 12  VAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQ-------AKKLGNNCVFAPAD 64

Query: 64  VSNLQSVFRASKELKQRFQRLDCIYLNAGI-MPNPQLNIKALFFGLFSRKVIHMFSTAEG 122
           V++ + V  A    K +F R+D     AGI + +   N+K                    
Sbjct: 65  VTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLK-------------------- 104

Query: 123 LLTQGDKITADGLQEVFETNVFGHFILIRELEPLLCHSDNPSQLIWTSSRSARKSNFSLE 182
              +G   T +  Q V + N+ G F +IR +   +  ++ P Q      R    +  S+ 
Sbjct: 105 ---KGQTHTLEDFQRVLDVNLMGTFNVIRLVAGEMGQNE-PDQ---GGQRGVIINTASVA 157

Query: 183 DFQHSKGKEPYSSSKYATDLLSVALNRNFNQQGLYSNVACPG 224
            F+   G+  YS+SK     +++ + R+    G+      PG
Sbjct: 158 AFEGQVGQAAYSASKGGIVGMTLPIARDLAPIGIRVMTIAPG 199


>gi|150247226 retinol dehydrogenase 16 [Homo sapiens]
          Length = 317

 Score = 36.6 bits (83), Expect = 0.033
 Identities = 56/229 (24%), Positives = 92/229 (40%), Gaps = 44/229 (19%)

Query: 3   KVVLITGASSGIGLALCKRLLAEDDELHLCLACRNMSKAEAVCAALLASHPTAEVTIVQV 62
           K V ITG  SG G  L ++L A    L +  AC     AE      L    +  +  V +
Sbjct: 30  KYVFITGCDSGFGKLLARQLDARG--LRVLAACLTEKGAEQ-----LRGQTSDRLETVTL 82

Query: 63  DVSNLQSVFRASKELKQRFQRLDCIYLNAGIMPNPQLNIKALFFGLFSRKVIHMFSTAEG 122
           DV+  +SV  A++ +K      +C+  + G+            +GL +   I + +    
Sbjct: 83  DVTKTESVAAAAQWVK------ECV-RDKGL------------WGLVNNAGISLPTAPNE 123

Query: 123 LLTQGDKITADGLQEVFETNVFGHFILIRELEPLLCHSDNPSQLIWTSSRSARKSNFSLE 182
           LLT+ D +T      + + N+ G   +   L PL+  +    +++  SS   R S F   
Sbjct: 124 LLTKQDFVT------ILDVNLLGVIDVTLSLLPLVRRA--RGRVVNVSSVMGRVSLFG-- 173

Query: 183 DFQHSKGKEPYSSSKYATDLLSVALNRNFNQQGLYSNVACPGTALTNLT 231
                     Y  SKY  +  S +L R  +  G+   +  PG   T +T
Sbjct: 174 --------GGYCISKYGVEAFSDSLRRELSYFGVKVAMIEPGYFKTAVT 214


>gi|83715985 hydroxysteroid (17-beta) dehydrogenase 10 isoform 2
           [Homo sapiens]
          Length = 252

 Score = 36.2 bits (82), Expect = 0.043
 Identities = 49/215 (22%), Positives = 86/215 (40%), Gaps = 35/215 (16%)

Query: 4   VVLITGASSGIGLALCKRLLAEDDELHLCLACRNMSKAEAVCAALLASHPTAEVTIVQVD 63
           V +ITG +SG+GLA  +RL+ +     L     +  +A+       A            D
Sbjct: 12  VAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQ-------AKKLGNNCVFAPAD 64

Query: 64  VSNLQSVFRASKELKQRFQRLDCIYLNAGI-MPNPQLNIKALFFGLFSRKVIHMFSTAEG 122
           V++ + V  A    K +F R+D     AGI + +   N+K                    
Sbjct: 65  VTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLK-------------------- 104

Query: 123 LLTQGDKITADGLQEVFETNVFGHFILIRELEPLLCHSDNPSQLIWTSSRSARKSNFSLE 182
              +G   T +  Q V + N+ G F +IR +   +  ++ P Q      R    +  S+ 
Sbjct: 105 ---KGQTHTLEDFQRVLDVNLMGTFNVIRLVAGEMGQNE-PDQ---GGQRGVIINTASVA 157

Query: 183 DFQHSKGKEPYSSSKYATDLLSVALNRNFNQQGLY 217
            F+   G+  YS+SK     +++ + R+    GL+
Sbjct: 158 AFEGQVGQAAYSASKGGIVGMTLPIARDLAPIGLF 192


>gi|4504503 hydroxysteroid (17-beta) dehydrogenase 2 [Homo sapiens]
          Length = 387

 Score = 35.8 bits (81), Expect = 0.057
 Identities = 52/237 (21%), Positives = 86/237 (36%), Gaps = 57/237 (24%)

Query: 2   RKVVLITGASSGIGLALCKRLLAEDDELHLCLACRNMSKAEAVCAALLASHPTAEVTIVQ 61
           +K VL+TG   G+G ALCK L    DEL   +    +++     A  L    +  ++++Q
Sbjct: 82  QKAVLVTGGDCGLGHALCKYL----DELGFTVFAGVLNE-NGPGAEELRRTCSPRLSVLQ 136

Query: 62  VDVSNLQSVFRASKELKQRFQR--LDCIYLNAGIMPNPQLNIKALFFGLFSRKVIHMFST 119
           +D++    +  A  ++    Q   L  +  NAG++                         
Sbjct: 137 MDITKPVQIKDAYSKVAAMLQDRGLWAVINNAGVL------------------------- 171

Query: 120 AEGLLTQGDKITADGLQEVFETNVFGHFILIRELEPLLCHSDNPSQLIWTSSRSARKSNF 179
             G  T G+ +     ++    N FG   + +   PLL                 RKS  
Sbjct: 172 --GFPTDGELLLMTDYKQCMAVNFFGTVEVTKTFLPLL-----------------RKSKG 212

Query: 180 SLEDFQHSKGKEP------YSSSKYATDLLSVALNRNFNQQGLYSNVACPGTALTNL 230
            L +     G  P      Y SSK A  + S  +    ++ G+      PG  LTN+
Sbjct: 213 RLVNVSSMGGGAPMERLASYGSSKAAVTMFSSVMRLELSKWGIKVASIQPGGFLTNI 269


>gi|109715829 short-chain dehydrogenase/reductase [Homo sapiens]
          Length = 260

 Score = 35.8 bits (81), Expect = 0.057
 Identities = 47/234 (20%), Positives = 91/234 (38%), Gaps = 42/234 (17%)

Query: 3   KVVLITGASSGIGLALCKRLLAEDDELHLCLACRNMSKAEAVCAALLASHPTAEVTIVQV 62
           ++ L+TGAS GIG A+ + L+ +  ++  C   R +   E + A   ++     +   + 
Sbjct: 12  RLALVTGASGGIGAAVARALVQQGLKVVGC--ARTVGNIEELAAECKSAGYPGTLIPYRC 69

Query: 63  DVSNLQSVFRASKELKQRFQRLDCIYLNAGIMPNPQLNIKALFFGLFSRKVIHMFSTAEG 122
           D+SN + +      ++ +   +D    NAG+                        +  + 
Sbjct: 70  DLSNEEDILSMFSAIRSQHSGVDICINNAGL------------------------ARPDT 105

Query: 123 LLTQGDKITADGLQEVFETNVFGHFILIRE-LEPLLCHSDNPSQLIWTSSRSA-RKSNFS 180
           LL+     +  G +++F  NV    I  RE  + +   + +   +I  +S S  R    S
Sbjct: 106 LLSG----STSGWKDMFNVNVLALSICTREAYQSMKERNVDDGHIININSMSGHRVLPLS 161

Query: 181 LEDFQHSKGKEPYSSSKYATDLLSVALNRNFNQQGLYSNVAC--PGTALTNLTY 232
           +  F        YS++KYA   L+  L +   +   +    C  PG   T   +
Sbjct: 162 VTHF--------YSATKYAVTALTEGLRQELREAQTHIRATCISPGVVETQFAF 207


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.135    0.398 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,037,583
Number of Sequences: 37866
Number of extensions: 488093
Number of successful extensions: 1304
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 18
Number of HSP's successfully gapped in prelim test: 33
Number of HSP's that attempted gapping in prelim test: 1246
Number of HSP's gapped (non-prelim): 63
length of query: 341
length of database: 18,247,518
effective HSP length: 103
effective length of query: 238
effective length of database: 14,347,320
effective search space: 3414662160
effective search space used: 3414662160
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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