Guide to the Human Genome
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Search of human proteins with 14042927

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|14042927 MLN64 N-terminal homolog [Homo sapiens]
         (234 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|14042927 MLN64 N-terminal homolog [Homo sapiens]                   464   e-131
gi|31543657 StAR-related lipid transfer (START) domain containin...   254   4e-68
gi|4503523 eukaryotic translation initiation factor 3 subunit D ...    30   1.4  
gi|4502889 ceroid-lipofuscinosis, neuronal 3 [Homo sapiens]            30   2.3  
gi|109698601 ceroid-lipofuscinosis, neuronal 3 [Homo sapiens]          30   2.3  
gi|157738619 smoothelin-like 1 [Homo sapiens]                          29   3.0  
gi|239751284 PREDICTED: hypothetical protein XP_002347797 [Homo ...    28   6.8  
gi|52630440 FK506-binding protein 8 [Homo sapiens]                     28   6.8  
gi|93352554 GPR158-like 1 [Homo sapiens]                               28   6.8  
gi|21493022 A kinase (PRKA) anchor protein 12 isoform 1 [Homo sa...    28   8.9  
gi|21493024 A kinase (PRKA) anchor protein 12 isoform 2 [Homo sa...    28   8.9  
gi|20149594 heat shock 90kDa protein 1, beta [Homo sapiens]            28   8.9  
gi|38348294 hypothetical protein LOC339145 [Homo sapiens]              28   8.9  
gi|29171759 adenylate cyclase activating polypeptide 1 (pituitar...    28   8.9  

>gi|14042927 MLN64 N-terminal homolog [Homo sapiens]
          Length = 234

 Score =  464 bits (1195), Expect = e-131
 Identities = 234/234 (100%), Positives = 234/234 (100%)

Query: 1   MNHLPEDMENALTGSQSSHASLRNIHSINPTQLMARIESYEGREKKGISDVRRTFCLFVT 60
           MNHLPEDMENALTGSQSSHASLRNIHSINPTQLMARIESYEGREKKGISDVRRTFCLFVT
Sbjct: 1   MNHLPEDMENALTGSQSSHASLRNIHSINPTQLMARIESYEGREKKGISDVRRTFCLFVT 60

Query: 61  FDLLFVTLLWIIELNVNGGIENTLEKEVMQYDYYSSYFDIFLLAVFRFKVLILAYAVCRL 120
           FDLLFVTLLWIIELNVNGGIENTLEKEVMQYDYYSSYFDIFLLAVFRFKVLILAYAVCRL
Sbjct: 61  FDLLFVTLLWIIELNVNGGIENTLEKEVMQYDYYSSYFDIFLLAVFRFKVLILAYAVCRL 120

Query: 121 RHWWAIALTTAVTSAFLLAKVILSKLFSQGAFGYVLPIISFILAWIETWFLDFKVLPQEA 180
           RHWWAIALTTAVTSAFLLAKVILSKLFSQGAFGYVLPIISFILAWIETWFLDFKVLPQEA
Sbjct: 121 RHWWAIALTTAVTSAFLLAKVILSKLFSQGAFGYVLPIISFILAWIETWFLDFKVLPQEA 180

Query: 181 EEENRLLIVQDASERAALIPGGLSDGQFYSPPESEAGSEEAEEKQDSEKPLLEL 234
           EEENRLLIVQDASERAALIPGGLSDGQFYSPPESEAGSEEAEEKQDSEKPLLEL
Sbjct: 181 EEENRLLIVQDASERAALIPGGLSDGQFYSPPESEAGSEEAEEKQDSEKPLLEL 234


>gi|31543657 StAR-related lipid transfer (START) domain containing 3
           [Homo sapiens]
          Length = 445

 Score =  254 bits (649), Expect = 4e-68
 Identities = 131/232 (56%), Positives = 167/232 (71%), Gaps = 17/232 (7%)

Query: 4   LPEDMENALT-----GSQSSHASLRNIHSINPTQLMARIESYEGREKKGISDVRRTFCLF 58
           L  D+E +L      GS  SH+   + H + P +           +++ ISDVRRTFCLF
Sbjct: 8   LTRDLERSLPAVASLGSSLSHSQSLSSHLLPPPE-----------KRRAISDVRRTFCLF 56

Query: 59  VTFDLLFVTLLWIIELNVNGGIENTLEKEVMQYDYYSSYFDIFLLAVFRFKVLILAYAVC 118
           VTFDLLF++LLWIIELN N GI   LE+E++QY++ +S+FDIF+LA FRF  L+L YAV 
Sbjct: 57  VTFDLLFISLLWIIELNTNTGIRKNLEQEIIQYNFKTSFFDIFVLAFFRFSGLLLGYAVL 116

Query: 119 RLRHWWAIALTTAVTSAFLLAKVILSKLFSQGAFGYVLPIISFILAWIETWFLDFKVLPQ 178
           RLRHWW IA+TT V+SAFL+ KVILS+L S+GAFGY+LPI+SF+LAW+ETWFLDFKVLPQ
Sbjct: 117 RLRHWWVIAVTTLVSSAFLIVKVILSELLSKGAFGYLLPIVSFVLAWLETWFLDFKVLPQ 176

Query: 179 EAEEENRLLIVQDASERAALI-PGGLSDGQFYSPPESEAGSEEAEEKQDSEK 229
           EAEEE   L  Q A  R  L+  G LS+GQFYSPPES A S+   +++ + K
Sbjct: 177 EAEEERWYLAAQVAVARGPLLFSGALSEGQFYSPPESFAASDNESDEEVAGK 228


>gi|4503523 eukaryotic translation initiation factor 3 subunit D
           [Homo sapiens]
          Length = 548

 Score = 30.4 bits (67), Expect = 1.4
 Identities = 16/47 (34%), Positives = 27/47 (57%), Gaps = 1/47 (2%)

Query: 182 EENRLLIVQDASERAALIPGGLSDGQFYSPPESEAGSEEAEEKQDSE 228
           EE + LI++D +++   +   L DG F S  + E   EE EE+++ E
Sbjct: 502 EEGKYLILKDPNKQVIRVYS-LPDGTFSSDEDEEEEEEEEEEEEEEE 547


>gi|4502889 ceroid-lipofuscinosis, neuronal 3 [Homo sapiens]
          Length = 438

 Score = 29.6 bits (65), Expect = 2.3
 Identities = 27/93 (29%), Positives = 38/93 (40%), Gaps = 21/93 (22%)

Query: 64  LFVTLLWII---------ELNVNGGIE------NTLEKEVMQYDYYSSYFDIFLLAVFRF 108
           +F  LLW I         E  +N G+       NT      QY +Y     ++   VF  
Sbjct: 277 VFKGLLWYIVPLVVVYFAEYFINQGLFELLFFWNTSLSHAQQYRWYQM---LYQAGVFAS 333

Query: 109 KVLILAYAVCRLRHWWAIALTTAVTSAFLLAKV 141
           +  +     CR+R  WA+AL   +   FLLA V
Sbjct: 334 RSSLRC---CRIRFTWALALLQCLNLVFLLADV 363


>gi|109698601 ceroid-lipofuscinosis, neuronal 3 [Homo sapiens]
          Length = 438

 Score = 29.6 bits (65), Expect = 2.3
 Identities = 27/93 (29%), Positives = 38/93 (40%), Gaps = 21/93 (22%)

Query: 64  LFVTLLWII---------ELNVNGGIE------NTLEKEVMQYDYYSSYFDIFLLAVFRF 108
           +F  LLW I         E  +N G+       NT      QY +Y     ++   VF  
Sbjct: 277 VFKGLLWYIVPLVVVYFAEYFINQGLFELLFFWNTSLSHAQQYRWYQM---LYQAGVFAS 333

Query: 109 KVLILAYAVCRLRHWWAIALTTAVTSAFLLAKV 141
           +  +     CR+R  WA+AL   +   FLLA V
Sbjct: 334 RSSLRC---CRIRFTWALALLQCLNLVFLLADV 363


>gi|157738619 smoothelin-like 1 [Homo sapiens]
          Length = 512

 Score = 29.3 bits (64), Expect = 3.0
 Identities = 15/55 (27%), Positives = 32/55 (58%), Gaps = 1/55 (1%)

Query: 174 KVLPQEAEEENRLLIVQDASERAALIPGGLSDGQFYSPPESEAGSEEAEEKQDSE 228
           K   +EA+ E++  +V+D ++     P G  + +  +  E++A  EEAE+ +++E
Sbjct: 210 KATDEEAKAESQKAVVEDEAKAEPKEPDGKEEAKHGAKEEADA-KEEAEDAEEAE 263


>gi|239751284 PREDICTED: hypothetical protein XP_002347797 [Homo
            sapiens]
          Length = 1674

 Score = 28.1 bits (61), Expect = 6.8
 Identities = 17/52 (32%), Positives = 28/52 (53%), Gaps = 7/52 (13%)

Query: 174  KVLPQEAEEENRLLIVQDASERAALIPGGLSDGQFYSPPESEAGSEEAEEKQ 225
            +V P EA+E          SE+A + P  +S+G      + +AGSE AE+++
Sbjct: 1107 EVCPWEAQEAA-------TSEKAKICPWEVSEGTTGKGLDQKAGSESAEQRE 1151


>gi|52630440 FK506-binding protein 8 [Homo sapiens]
          Length = 413

 Score = 28.1 bits (61), Expect = 6.8
 Identities = 17/47 (36%), Positives = 24/47 (51%), Gaps = 3/47 (6%)

Query: 191 DASERAALIPGG---LSDGQFYSPPESEAGSEEAEEKQDSEKPLLEL 234
           + SE +A +P G   L D +     E   G EE EE+++ E  L EL
Sbjct: 6   EPSEPSAPLPAGVPPLEDFEVLDGVEDAEGEEEEEEEEEEEDDLSEL 52


>gi|93352554 GPR158-like 1 [Homo sapiens]
          Length = 2367

 Score = 28.1 bits (61), Expect = 6.8
 Identities = 17/52 (32%), Positives = 28/52 (53%), Gaps = 7/52 (13%)

Query: 174  KVLPQEAEEENRLLIVQDASERAALIPGGLSDGQFYSPPESEAGSEEAEEKQ 225
            +V P EA+E          SE+A + P  +S+G      + +AGSE AE+++
Sbjct: 1800 EVCPWEAQEAA-------TSEKAKICPWEVSEGTTGKGLDQKAGSESAEQRE 1844


>gi|21493022 A kinase (PRKA) anchor protein 12 isoform 1 [Homo
           sapiens]
          Length = 1782

 Score = 27.7 bits (60), Expect = 8.9
 Identities = 18/45 (40%), Positives = 24/45 (53%), Gaps = 4/45 (8%)

Query: 186 LLIVQDASERAALIPGGLSDGQFYSPPESEAGSEEAEEKQDSEKP 230
           L + +D  E AA    G  D +  S    EA S+E+E KQ +EKP
Sbjct: 199 LTVKKDEGEGAA----GAGDHKDPSLGAGEAASKESEPKQSTEKP 239


>gi|21493024 A kinase (PRKA) anchor protein 12 isoform 2 [Homo
           sapiens]
          Length = 1684

 Score = 27.7 bits (60), Expect = 8.9
 Identities = 18/45 (40%), Positives = 24/45 (53%), Gaps = 4/45 (8%)

Query: 186 LLIVQDASERAALIPGGLSDGQFYSPPESEAGSEEAEEKQDSEKP 230
           L + +D  E AA    G  D +  S    EA S+E+E KQ +EKP
Sbjct: 101 LTVKKDEGEGAA----GAGDHKDPSLGAGEAASKESEPKQSTEKP 141


>gi|20149594 heat shock 90kDa protein 1, beta [Homo sapiens]
          Length = 724

 Score = 27.7 bits (60), Expect = 8.9
 Identities = 11/21 (52%), Positives = 14/21 (66%)

Query: 213 ESEAGSEEAEEKQDSEKPLLE 233
           E E G +E E+K D EKP +E
Sbjct: 231 EEEKGEKEEEDKDDEEKPKIE 251


>gi|38348294 hypothetical protein LOC339145 [Homo sapiens]
          Length = 304

 Score = 27.7 bits (60), Expect = 8.9
 Identities = 9/28 (32%), Positives = 21/28 (75%)

Query: 38  ESYEGREKKGISDVRRTFCLFVTFDLLF 65
           E+ +G +++ + D+++ FC FVT +++F
Sbjct: 165 ETVDGFQRQKLKDLQKFFCDFVTIEMVF 192


>gi|29171759 adenylate cyclase activating polypeptide 1 (pituitary)
           receptor type I precursor [Homo sapiens]
          Length = 468

 Score = 27.7 bits (60), Expect = 8.9
 Identities = 23/77 (29%), Positives = 42/77 (54%), Gaps = 9/77 (11%)

Query: 57  LFVTFDLLFVTLL---WII--ELNVNGGIENTLE-KEVMQYDYY---SSYFDIFLLAVFR 107
           LFV+F L  +++    WI+  E + N    +T+E K VM + +Y   S+YF +F+  ++ 
Sbjct: 192 LFVSFMLRAISVFIKDWILYAEQDSNHCFISTVECKAVMVFFHYCVVSNYFWLFIEGLYL 251

Query: 108 FKVLILAYAVCRLRHWW 124
           F +L+  +   R   +W
Sbjct: 252 FTLLVETFFPERRYFYW 268


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.137    0.403 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,261,832
Number of Sequences: 37866
Number of extensions: 325599
Number of successful extensions: 1339
Number of sequences better than 10.0: 14
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 1330
Number of HSP's gapped (non-prelim): 16
length of query: 234
length of database: 18,247,518
effective HSP length: 99
effective length of query: 135
effective length of database: 14,498,784
effective search space: 1957335840
effective search space used: 1957335840
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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