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Search of human proteins with 7662168
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7662168 suppression of tumorigenicity 18 [Homo sapiens]
(1047 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7662168 suppression of tumorigenicity 18 [Homo sapiens] 2127 0.0
gi|17975763 myelin transcription factor 1 [Homo sapiens] 836 0.0
gi|60498973 myelin transcription factor 1-like [Homo sapiens] 759 0.0
gi|117938328 l(3)mbt-like isoform I [Homo sapiens] 62 4e-09
gi|117938330 l(3)mbt-like isoform II [Homo sapiens] 62 4e-09
gi|5901962 MYST histone acetyltransferase 2 [Homo sapiens] 48 6e-05
gi|158138528 l(3)mbt-like 4 [Homo sapiens] 47 1e-04
gi|16445033 ACRC protein [Homo sapiens] 46 2e-04
gi|31982906 cingulin-like 1 [Homo sapiens] 44 6e-04
gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo ... 41 0.005
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 41 0.007
gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens] 40 0.009
gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens] 40 0.009
gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens] 40 0.009
gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens] 40 0.009
gi|229577185 epidermal growth factor receptor pathway substrate ... 40 0.011
gi|4503593 epidermal growth factor receptor pathway substrate 15... 40 0.011
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo... 40 0.011
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo... 40 0.011
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo... 40 0.011
gi|83715964 high-mobility group 20B [Homo sapiens] 39 0.020
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [... 39 0.020
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 39 0.033
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s... 38 0.044
gi|46049114 M-phase phosphoprotein 1 [Homo sapiens] 38 0.044
gi|197276602 microtubule-associated protein 4 isoform 5 [Homo sa... 38 0.057
gi|47519616 tropomyosin 2 (beta) isoform 2 [Homo sapiens] 38 0.057
gi|224922812 tropomyosin 2 (beta) isoform 3 [Homo sapiens] 38 0.057
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H... 38 0.057
gi|157738615 coiled-coil alpha-helical rod protein 1 isoform 1 [... 38 0.057
>gi|7662168 suppression of tumorigenicity 18 [Homo sapiens]
Length = 1047
Score = 2127 bits (5510), Expect = 0.0
Identities = 1047/1047 (100%), Positives = 1047/1047 (100%)
Query: 1 MDAEAEDKTLRTRSKGTEVPMDSLIQELSVAYDCSMAKKRTAEDQALGVPVNKRKSLLMK 60
MDAEAEDKTLRTRSKGTEVPMDSLIQELSVAYDCSMAKKRTAEDQALGVPVNKRKSLLMK
Sbjct: 1 MDAEAEDKTLRTRSKGTEVPMDSLIQELSVAYDCSMAKKRTAEDQALGVPVNKRKSLLMK 60
Query: 61 PRHYSPKADCQEDRSDRTEDDGPLETHGHSTAEEIMIKPMDESLLSTAQENSSRKEDRYS 120
PRHYSPKADCQEDRSDRTEDDGPLETHGHSTAEEIMIKPMDESLLSTAQENSSRKEDRYS
Sbjct: 61 PRHYSPKADCQEDRSDRTEDDGPLETHGHSTAEEIMIKPMDESLLSTAQENSSRKEDRYS 120
Query: 121 CYQELMVKSLMHLGKFEKNVSVQTVSENLNDSGIQSLKAESDEADECFLIHSDDGRDKID 180
CYQELMVKSLMHLGKFEKNVSVQTVSENLNDSGIQSLKAESDEADECFLIHSDDGRDKID
Sbjct: 121 CYQELMVKSLMHLGKFEKNVSVQTVSENLNDSGIQSLKAESDEADECFLIHSDDGRDKID 180
Query: 181 DSQPPFCSSDDNESNSESAENGWDSGSNFSEETKPPRVPKYVLTDHKKDLLEVPEIKTEG 240
DSQPPFCSSDDNESNSESAENGWDSGSNFSEETKPPRVPKYVLTDHKKDLLEVPEIKTEG
Sbjct: 181 DSQPPFCSSDDNESNSESAENGWDSGSNFSEETKPPRVPKYVLTDHKKDLLEVPEIKTEG 240
Query: 241 DKFIPCENRCDSETERKDPQNALAEPLDGNAQPSFPDVEEEDSESLAVMTEEGSDLEKAK 300
DKFIPCENRCDSETERKDPQNALAEPLDGNAQPSFPDVEEEDSESLAVMTEEGSDLEKAK
Sbjct: 241 DKFIPCENRCDSETERKDPQNALAEPLDGNAQPSFPDVEEEDSESLAVMTEEGSDLEKAK 300
Query: 301 GNLSLLEQAIALQAERGCVFHNTYKELDRFLLEHLAGERRQTKVIDMGGRQIFNNKHSPR 360
GNLSLLEQAIALQAERGCVFHNTYKELDRFLLEHLAGERRQTKVIDMGGRQIFNNKHSPR
Sbjct: 301 GNLSLLEQAIALQAERGCVFHNTYKELDRFLLEHLAGERRQTKVIDMGGRQIFNNKHSPR 360
Query: 361 PEKRETKCPIPGCDGTGHVTGLYPHHRSLSGCPHKVRVPLEILAMHENVLKCPTPGCTGR 420
PEKRETKCPIPGCDGTGHVTGLYPHHRSLSGCPHKVRVPLEILAMHENVLKCPTPGCTGR
Sbjct: 361 PEKRETKCPIPGCDGTGHVTGLYPHHRSLSGCPHKVRVPLEILAMHENVLKCPTPGCTGR 420
Query: 421 GHVNSNRNTHRSLSGCPIAAAEKLAMSQDKNQLDSPQTGQCPDQAHRTSLVKQIEFNFPS 480
GHVNSNRNTHRSLSGCPIAAAEKLAMSQDKNQLDSPQTGQCPDQAHRTSLVKQIEFNFPS
Sbjct: 421 GHVNSNRNTHRSLSGCPIAAAEKLAMSQDKNQLDSPQTGQCPDQAHRTSLVKQIEFNFPS 480
Query: 481 QAITSPRATVSKEQEKFGKVPFDYASFDAQVFGKRPLIQTVQGRKTPPFPESKHFPNPVK 540
QAITSPRATVSKEQEKFGKVPFDYASFDAQVFGKRPLIQTVQGRKTPPFPESKHFPNPVK
Sbjct: 481 QAITSPRATVSKEQEKFGKVPFDYASFDAQVFGKRPLIQTVQGRKTPPFPESKHFPNPVK 540
Query: 541 FPNRLPSAGAHTQSPGRASSYSYGQCSEDTHIAAAAAILNLSTRCREATDILSNKPQSLH 600
FPNRLPSAGAHTQSPGRASSYSYGQCSEDTHIAAAAAILNLSTRCREATDILSNKPQSLH
Sbjct: 541 FPNRLPSAGAHTQSPGRASSYSYGQCSEDTHIAAAAAILNLSTRCREATDILSNKPQSLH 600
Query: 601 AKGAEIEVDENGTLDLSMKKNRILDKSAPLTSSNTSIPTPSSSPFKTSSILVNAAFYQAL 660
AKGAEIEVDENGTLDLSMKKNRILDKSAPLTSSNTSIPTPSSSPFKTSSILVNAAFYQAL
Sbjct: 601 AKGAEIEVDENGTLDLSMKKNRILDKSAPLTSSNTSIPTPSSSPFKTSSILVNAAFYQAL 660
Query: 661 CDQEGWDTPINYSKTHGKTEEEKEKDPVSSLENLEEKKFPGEASIPSPKPKLHARDLKKE 720
CDQEGWDTPINYSKTHGKTEEEKEKDPVSSLENLEEKKFPGEASIPSPKPKLHARDLKKE
Sbjct: 661 CDQEGWDTPINYSKTHGKTEEEKEKDPVSSLENLEEKKFPGEASIPSPKPKLHARDLKKE 720
Query: 721 LITCPTPGCDGSGHVTGNYASHRSVSGCPLADKTLKSLMAANSQELKCPTPGCDGSGHVT 780
LITCPTPGCDGSGHVTGNYASHRSVSGCPLADKTLKSLMAANSQELKCPTPGCDGSGHVT
Sbjct: 721 LITCPTPGCDGSGHVTGNYASHRSVSGCPLADKTLKSLMAANSQELKCPTPGCDGSGHVT 780
Query: 781 GNYASHRSLSGCPRARKGGVKMTPTKEEKEDPELKCPVIGCDGQGHISGKYTSHRTASGC 840
GNYASHRSLSGCPRARKGGVKMTPTKEEKEDPELKCPVIGCDGQGHISGKYTSHRTASGC
Sbjct: 781 GNYASHRSLSGCPRARKGGVKMTPTKEEKEDPELKCPVIGCDGQGHISGKYTSHRTASGC 840
Query: 841 PLAAKRQKENPLNGASLSWKLNKQELPHCPLPGCNGLGHVNNVFVTHRSLSGCPLNAQVI 900
PLAAKRQKENPLNGASLSWKLNKQELPHCPLPGCNGLGHVNNVFVTHRSLSGCPLNAQVI
Sbjct: 841 PLAAKRQKENPLNGASLSWKLNKQELPHCPLPGCNGLGHVNNVFVTHRSLSGCPLNAQVI 900
Query: 901 KKGKVSEELMTIKLKATGGIESDEEIRHLDEEIKELNESNLKIEADMMKLQTQITSMESN 960
KKGKVSEELMTIKLKATGGIESDEEIRHLDEEIKELNESNLKIEADMMKLQTQITSMESN
Sbjct: 901 KKGKVSEELMTIKLKATGGIESDEEIRHLDEEIKELNESNLKIEADMMKLQTQITSMESN 960
Query: 961 LKTIEEENKLIEQNNESLLKELAGLSQALISSLADIQLPQMGPISEQNFEAYVNTLTDMY 1020
LKTIEEENKLIEQNNESLLKELAGLSQALISSLADIQLPQMGPISEQNFEAYVNTLTDMY
Sbjct: 961 LKTIEEENKLIEQNNESLLKELAGLSQALISSLADIQLPQMGPISEQNFEAYVNTLTDMY 1020
Query: 1021 SNLERDYSPECKALLESIKQAVKGIHV 1047
SNLERDYSPECKALLESIKQAVKGIHV
Sbjct: 1021 SNLERDYSPECKALLESIKQAVKGIHV 1047
>gi|17975763 myelin transcription factor 1 [Homo sapiens]
Length = 1121
Score = 836 bits (2159), Expect = 0.0
Identities = 528/1163 (45%), Positives = 682/1163 (58%), Gaps = 158/1163 (13%)
Query: 1 MDAEAEDKTLRTRSKGTEVPMDSLIQELSVA--------------------YDCSMAKKR 40
M E EDK RTRSK P ++ +LS C +AKKR
Sbjct: 1 MSLENEDKRARTRSKALRGPPETTAADLSCPTPGCTGSGHVRGKYSRHRSLQSCPLAKKR 60
Query: 41 TAEDQALGVPVNKRKSLLMK---PRHYSPKADCQEDR-----SDRTEDDGPLE-THGHST 91
E V+KRKS +K Y +D ED S E +G LE ++
Sbjct: 61 KLEGAEAEHLVSKRKSHPLKLALDEGYGVDSDGSEDTEVKDASVSDESEGTLEGAEAETS 120
Query: 92 AEEIMIKPMDESLLSTAQEN---------SSRKEDRYSCYQELMVKSLMHLGKFEKNVSV 142
++ + +P S + + ++ + YS YQ ++ SL++LG+ + V
Sbjct: 121 GQDEIHRPETAEGRSPVKSHFGSNPIGSATASSKGSYSSYQGIIATSLLNLGQIAEETLV 180
Query: 143 QTVSENLNDS-----GIQSLKAE------SDEADECFLIHSDDGRDKID---DSQPPFC- 187
+ E+L + GI L E S+E ++ I +D + ++ + C
Sbjct: 181 E---EDLGQAAKPGPGIVHLLQEAAEGAASEEGEKGLFIQPEDAEEVVEVTTERSQDLCP 237
Query: 188 -SSDDNESNSESAENGWDSGSNFSEETKPPRVPKYVLTDHKKDLLEVPEIKTEGDKFIPC 246
S +D S S + G S EE + + + +++ E E + E ++
Sbjct: 238 QSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEE 297
Query: 247 ENRCDSETE-------RKDPQNALAEPLDGNAQPSFP---------------DVEEEDSE 284
E + E E ++D + A+ P P D ++ED+
Sbjct: 298 EEEEEEEEEAAPDVIFQEDTSHTSAQKAPELRGPESPSPKPEYSVIVEVRSDDDKDEDTH 357
Query: 285 SLAVMTEEGSDLEK--AKGNLSLLEQAIALQAER-GCVFHNTYKELDRFLLEHLAGERRQ 341
S + S+++ +GNL LLEQAIAL+AE+ V ++ L L +
Sbjct: 358 SRKSTVTDESEMQDMMTRGNLGLLEQAIALKAEQVRTVCEPGCPPAEQSQLG-LGEPGKA 416
Query: 342 TKVIDMGGRQIFNNKHSPRPEKRETKCPIPGCDGTGHVTGLYPHHRSLSGCPHKVRVPLE 401
K +D R+ + +K R EKRE KCP PGCDGTGHVTGLYPHHRSLSGCPHK R+P E
Sbjct: 417 AKPLDTV-RKSYYSKDPSRAEKREIKCPTPGCDGTGHVTGLYPHHRSLSGCPHKDRIPPE 475
Query: 402 ILAMHENVLKCPTPGCTGRGHVNSNRNTHRSLSGCPIAAAEKLAMSQDKNQLDSPQTGQC 461
ILAMHENVLKCPTPGCTG+GHVNSNRNTHRSLSGCPIAAAEKLA S +K Q PQTG
Sbjct: 476 ILAMHENVLKCPTPGCTGQGHVNSNRNTHRSLSGCPIAAAEKLAKSHEKQQ---PQTGD- 531
Query: 462 PDQAHRTS--------LVKQIEFN-----FPSQAITSPRATVSKEQEKFGKVPFDYASFD 508
P ++ S VKQ+E P+ A +PRA ++KE EKF KV FDYASFD
Sbjct: 532 PSKSSSNSDRILRPMCFVKQLEVPPYGSYRPNVAPATPRANLAKELEKFSKVTFDYASFD 591
Query: 509 AQVFGKRPLIQTVQGRKTPPFPESKHFPNPVKFPNRLPSAGAHTQSPGRASSYSYGQCSE 568
AQVFGKR L +Q +T SP + Y Q +E
Sbjct: 592 AQVFGKRMLAPKIQTSET---------------------------SPKAFQCFDYSQDAE 624
Query: 569 DTHIAAAAAILNLSTRCREATDILSNKPQSLHAKGAEIEVDENGTLDLSMKKNRILDKSA 628
H+AA A ILNLSTRC E + LS KPQ L +K +IEVDENGTLDLSM K+R + +
Sbjct: 625 AAHMAATA-ILNLSTRCWEMPENLSTKPQDLPSKSVDIEVDENGTLDLSMHKHRKRENAF 683
Query: 629 PLTSSNTSIP---TPS-----SSPFKTSSILVNAAFYQALCDQEGWDTPINYSKTHGKTE 680
P +SS +S P +P SS SS + + QA Q+ WD P++Y+K E
Sbjct: 684 PSSSSCSSSPGVKSPDASQRHSSTSAPSSSMTSPQSSQA-SRQDEWDRPLDYTKPSRLRE 742
Query: 681 EEKEK--------------DPVSSLENLEEKKFPGEASIPSPKPKLHARDLKKELITCPT 726
EE E+ D S EN EE+K+PGE ++ + K K ++D+KKEL+TCPT
Sbjct: 743 EEPEESEPAAHSFASSEADDQEVSEENFEERKYPGEVTLTNFKLKFLSKDIKKELLTCPT 802
Query: 727 PGCDGSGHVTGNYASHRSVSGCPLADKTLKSLMAANSQELKCPTPGCDGSGHVTGNYASH 786
PGCDGSGH+TGNYASHRS+SGCPLADK+L++LMAA+S +LKCPTPGCDGSGH+TGNYASH
Sbjct: 803 PGCDGSGHITGNYASHRSLSGCPLADKSLRNLMAAHSADLKCPTPGCDGSGHITGNYASH 862
Query: 787 RSLSGCPRARKGGVKMTPTKEEKEDPEL-KCPVIGCDGQGHISGKYTSHRTASGCPLAAK 845
RSLSGCPRA+K GVK+ PTK++KEDPEL KCPV GC G GHISGKY SHR+ASGCPLAA+
Sbjct: 863 RSLSGCPRAKKSGVKVAPTKDDKEDPELMKCPVPGCVGLGHISGKYASHRSASGCPLAAR 922
Query: 846 RQKENPLNGASLSWKLNKQELPHCPLPGCNGLGHVNNVFVTHRSLSGCPLNAQVIKKGKV 905
RQKE LNG+S SWK K E P CP PGC+G GH N F+THRSLSGCP KKGK+
Sbjct: 923 RQKEGSLNGSSFSWKSLKNEGPTCPTPGCDGSGHANGSFLTHRSLSGCPRATFAGKKGKL 982
Query: 906 S-EELMTIKLKATGGIESDEEIRHLDEEIKELNESNLKIEADMMKLQTQITSMESNLKTI 964
S +E+++ K K + +E+DEEI+ L++EI++LNESN ++EA M++LQ+QI+SME NLK I
Sbjct: 983 SGDEVLSPKFKTSDVLENDEEIKQLNQEIRDLNESNSEMEAAMVQLQSQISSMEKNLKNI 1042
Query: 965 EEENKLIEQNNESLLKELAGLSQALISSLADIQLPQMGPISEQNFEAYVNTLTDMYSNLE 1024
EEENKLIE+ NE+L EL+GLSQALI SLA+I+LP M PI EQNF+AYV+TLTDMYSN +
Sbjct: 1043 EEENKLIEEQNEALFLELSGLSQALIQSLANIRLPHMEPICEQNFDAYVSTLTDMYSNQD 1102
Query: 1025 RDYSPECKALLESIKQAVKGIHV 1047
PE K LLESIKQAV+GI V
Sbjct: 1103 ----PENKDLLESIKQAVRGIQV 1121
>gi|60498973 myelin transcription factor 1-like [Homo sapiens]
Length = 1184
Score = 759 bits (1960), Expect = 0.0
Identities = 424/813 (52%), Positives = 546/813 (67%), Gaps = 80/813 (9%)
Query: 280 EEDSESLAVMTEEGSDL-EKAKGNLSLLEQAIALQAERGCVFH----------NTYKELD 328
E D ++ +V ++ ++ + KGNL+LLE+AIAL+ ER + + +
Sbjct: 407 ERDDDTTSVNSDRSEEVFDMTKGNLTLLEKAIALETERAKAMREKMAMEAGRRDNMRSYE 466
Query: 329 RFLLEHLAGERRQTKVIDMGGRQIFNNKHSPRPEKRETKCPIPGCDGTGHVTGLYPHHRS 388
L GE R+ K D ++ + + R EK+E+KCP PGCDGTGHVTGLYPHHRS
Sbjct: 467 DQSPRQLPGEDRKPKSSDSHVKKPYYDPS--RTEKKESKCPTPGCDGTGHVTGLYPHHRS 524
Query: 389 LSGCPHKVRVPLEILAMHENVLKCPTPGCTGRGHVNSNRNTHRSLSGCPIAAAEKLAMSQ 448
LSGCPHK RVP EILAMHE+VLKCPTPGCTGRGHVNSNRN+HRSLSGCPIAAAEKLA +Q
Sbjct: 525 LSGCPHKDRVPPEILAMHESVLKCPTPGCTGRGHVNSNRNSHRSLSGCPIAAAEKLAKAQ 584
Query: 449 DKNQ-LDSPQTGQCPDQAHRTS-LVKQIEF-------NFPSQAITSPRATVSKEQEKFGK 499
+K+Q D ++ Q D+ R VKQ+E N P+ T+PR+ ++KE EK+ K
Sbjct: 585 EKHQSCDVSKSSQASDRVLRPMCFVKQLEIPQYGYRNNVPT---TTPRSNLAKELEKYSK 641
Query: 500 VPFDYASFDAQVFGKRPLIQTVQGRKTPP--FPESKHF-----PNPVKFPNRLPSA---- 548
F+Y S+D +GKR + VQ R P + ++K + P+ + PS+
Sbjct: 642 TSFEYNSYDNHTYGKRAIAPKVQTRDISPKGYDDAKRYCKDPSPSSSSTSSYAPSSSSNL 701
Query: 549 ----GAHTQSPGRASSYSYGQCSEDTHIAAAAAILNLSTRCREATDILSNKPQSLHA-KG 603
G+ S SS+ Y E H+AA A ILNLSTRCRE LS KPQ L A +
Sbjct: 702 SCGGGSSASSTCSKSSFDYTHDMEAAHMAATA-ILNLSTRCREMPQNLSTKPQDLCATRN 760
Query: 604 AEIEVDENGTLDLSMKKNRILDKSAPLTSSNTSIPTPSSSPFKTSSILVNAAFYQALCDQ 663
++EVDENGTLDLSM K R D P+ + P SP + +++ N F L +
Sbjct: 761 PDMEVDENGTLDLSMNKQRPRDSCCPILT-----PLEPMSP-QQQAVMNNRCFQ--LGEG 812
Query: 664 EGWDTPINYSKTHGKTEEEKEKDPVSS------LENLEEKKFPGEASIPSPKPKL-HARD 716
+ WD P++Y+K + +E E ++ E LEE+++PGE +IPSPKPK ++
Sbjct: 813 DCWDLPVDYTKMKPRRIDEDESKDITPEDLDPFQEALEERRYPGEVTIPSPKPKYPQCKE 872
Query: 717 LKKELITCPTPGCDGSGHVTGNYASHRSVSGCPLADKTLKSLMAANSQELKCPTPGCDGS 776
KK+LIT +SGCPLADK+++S++A +SQELKCPTPGCDGS
Sbjct: 873 SKKDLIT---------------------LSGCPLADKSIRSMLATSSQELKCPTPGCDGS 911
Query: 777 GHVTGNYASHRSLSGCPRARKGGVKMTPTKEEKEDPE-LKCPVIGCDGQGHISGKYTSHR 835
GH+TGNYASHRSLSGCPRA+K G+++ +KE+KED E ++CPV GCDGQGHI+GKY SHR
Sbjct: 912 GHITGNYASHRSLSGCPRAKKSGIRIAQSKEDKEDQEPIRCPVPGCDGQGHITGKYASHR 971
Query: 836 TASGCPLAAKRQKENPLNGASLSWKLNKQELPHCPLPGCNGLGHVNNVFVTHRSLSGCPL 895
+ASGCPLAAKRQK+ LNG+ SWK K E CP PGC+G GHV+ F+THRSLSGCP
Sbjct: 972 SASGCPLAAKRQKDGYLNGSQFSWKSVKTEGMSCPTPGCDGSGHVSGSFLTHRSLSGCPR 1031
Query: 896 NAQVIKKGKVS-EELMTIKLKATGGIESDEEIRHLDEEIKELNESNLKIEADMMKLQTQI 954
+KK K+S E+++TIK +A+ GIE+DEEI+ LDEEIKELNESN ++EADM+KL+TQI
Sbjct: 1032 ATSAMKKAKLSGEQMLTIKQRASNGIENDEEIKQLDEEIKELNESNSQMEADMIKLRTQI 1091
Query: 955 TSMESNLKTIEEENKLIEQNNESLLKELAGLSQALISSLADIQLPQMGPISEQNFEAYVN 1014
T+MESNLKTIEEENK+IEQ NESLL ELA LSQ+LI SLA+IQLP M PI+EQNF+AYV
Sbjct: 1092 TTMESNLKTIEEENKVIEQQNESLLHELANLSQSLIHSLANIQLPHMDPINEQNFDAYVT 1151
Query: 1015 TLTDMYSNLERDYSPECKALLESIKQAVKGIHV 1047
TLT+MY+N +R SPE KALLE+IKQAV+GI V
Sbjct: 1152 TLTEMYTNQDRYQSPENKALLENIKQAVRGIQV 1184
Score = 65.5 bits (158), Expect = 3e-10
Identities = 27/35 (77%), Positives = 30/35 (85%)
Query: 719 KELITCPTPGCDGSGHVTGNYASHRSVSGCPLADK 753
+EL +CPTPGCDGSGHV+G YA HRSV GCPLA K
Sbjct: 26 QELFSCPTPGCDGSGHVSGKYARHRSVYGCPLAKK 60
Score = 60.8 bits (146), Expect = 6e-09
Identities = 30/55 (54%), Positives = 37/55 (67%), Gaps = 4/55 (7%)
Query: 764 QEL-KCPTPGCDGSGHVTGNYASHRSLSGCPRARKGGVKMTPTKEEKEDPELKCP 817
QEL CPTPGCDGSGHV+G YA HRS+ GCP A+K + T K+ +E + P
Sbjct: 26 QELFSCPTPGCDGSGHVSGKYARHRSVYGCPLAKK---RKTQDKQPQEPAPKRKP 77
Score = 56.6 bits (135), Expect = 1e-07
Identities = 58/239 (24%), Positives = 88/239 (36%), Gaps = 76/239 (31%)
Query: 1 MDAEAEDKTLRTRSKGTEVPMDSLIQEL---------------------SVAYDCSMAKK 39
M+ + E+K RTRSKG VP++ IQEL Y C +AKK
Sbjct: 1 MEVDTEEKRHRTRSKGVRVPVEPAIQELFSCPTPGCDGSGHVSGKYARHRSVYGCPLAKK 60
Query: 40 RTAEDQALGVPVNKRKSLLMKPRHYS----PKADCQEDRSDRTEDDG------------- 82
R +D+ P KRK +K S +D ED ++ ED+G
Sbjct: 61 RKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDE 120
Query: 83 PLETHGHSTAEEIMIKPMDE-------------------------------------SLL 105
E EE I+ DE + +
Sbjct: 121 DEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRI 180
Query: 106 STAQENSSRKEDRYSCYQELMVKSLMHLGKFEKNVSVQTVSEN-LNDSGIQSLKAESDE 163
E D Y Y EL+ KSL++LGK ++ + + +E+ +N + SL+ +SD+
Sbjct: 181 MQDTEKDDNNNDEYDNYDELVAKSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDSDK 239
Score = 56.2 bits (134), Expect = 2e-07
Identities = 26/57 (45%), Positives = 34/57 (59%), Gaps = 2/57 (3%)
Query: 794 RARKGGVKMTPTKEEKEDPELKCPVIGCDGQGHISGKYTSHRTASGCPLAAKRQKEN 850
R R GV++ +E CP GCDG GH+SGKY HR+ GCPLA KR+ ++
Sbjct: 11 RTRSKGVRVPVEPAIQE--LFSCPTPGCDGSGHVSGKYARHRSVYGCPLAKKRKTQD 65
Score = 51.6 bits (122), Expect = 4e-06
Identities = 26/55 (47%), Positives = 33/55 (60%), Gaps = 5/55 (9%)
Query: 396 VRVPLEILAMHENVLKCPTPGCTGRGHVNSNRNTHRSLSGCPIAAAEKLAMSQDK 450
VRVP+E + + CPTPGC G GHV+ HRS+ GCP+A K +QDK
Sbjct: 17 VRVPVEPAI--QELFSCPTPGCDGSGHVSGKYARHRSVYGCPLAKKRK---TQDK 66
Score = 49.7 bits (117), Expect = 1e-05
Identities = 18/26 (69%), Positives = 21/26 (80%)
Query: 368 CPIPGCDGTGHVTGLYPHHRSLSGCP 393
CP PGCDG+GHV+G Y HRS+ GCP
Sbjct: 31 CPTPGCDGSGHVSGKYARHRSVYGCP 56
Score = 47.8 bits (112), Expect = 6e-05
Identities = 19/32 (59%), Positives = 23/32 (71%)
Query: 864 QELPHCPLPGCNGLGHVNNVFVTHRSLSGCPL 895
QEL CP PGC+G GHV+ + HRS+ GCPL
Sbjct: 26 QELFSCPTPGCDGSGHVSGKYARHRSVYGCPL 57
>gi|117938328 l(3)mbt-like isoform I [Homo sapiens]
Length = 772
Score = 61.6 bits (148), Expect = 4e-09
Identities = 37/97 (38%), Positives = 49/97 (50%), Gaps = 11/97 (11%)
Query: 725 PTPGCDGSGH-----VTGNYASHRSVSGCP-LADKTLKSLMAA--NSQELKCPTPGCDGS 776
P C +GH + S S GCP L+ ++L + + KCPTPGCDGS
Sbjct: 503 PAGWCSKTGHPLQPPLGPREPSSASPGGCPPLSYRSLPHTRTSKYSFHHRKCPTPGCDGS 562
Query: 777 GHVTGNYASHRSLSGCPRARKGGVKMTPTKEEKEDPE 813
GHVTG + +H LSGCP A + ++ K E D E
Sbjct: 563 GHVTGKFTAHHCLSGCPLAERNQSRL---KAELSDSE 596
Score = 59.3 bits (142), Expect = 2e-08
Identities = 23/37 (62%), Positives = 28/37 (75%)
Query: 724 CPTPGCDGSGHVTGNYASHRSVSGCPLADKTLKSLMA 760
CPTPGCDGSGHVTG + +H +SGCPLA++ L A
Sbjct: 554 CPTPGCDGSGHVTGKFTAHHCLSGCPLAERNQSRLKA 590
Score = 57.0 bits (136), Expect = 9e-08
Identities = 31/84 (36%), Positives = 40/84 (47%), Gaps = 6/84 (7%)
Query: 769 PTPGCDGSGH-----VTGNYASHRSLSGCPRARKGGVKMTPTKEEKEDPELKCPVIGCDG 823
P C +GH + S S GCP + T T + KCP GCDG
Sbjct: 503 PAGWCSKTGHPLQPPLGPREPSSASPGGCPPLSYRSLPHTRTSKYSFHHR-KCPTPGCDG 561
Query: 824 QGHISGKYTSHRTASGCPLAAKRQ 847
GH++GK+T+H SGCPLA + Q
Sbjct: 562 SGHVTGKFTAHHCLSGCPLAERNQ 585
Score = 51.6 bits (122), Expect = 4e-06
Identities = 38/122 (31%), Positives = 52/122 (42%), Gaps = 19/122 (15%)
Query: 817 PVIGCDGQGH-----ISGKYTSHRTASGCPLAAKRQKENPLNGASLSW-KLNKQELPH-- 868
P C GH + + S + GCP PL+ SL + +K H
Sbjct: 503 PAGWCSKTGHPLQPPLGPREPSSASPGGCP---------PLSYRSLPHTRTSKYSFHHRK 553
Query: 869 CPLPGCNGLGHVNNVFVTHRSLSGCPL--NAQVIKKGKVSEELMTIKLKATGGIESDEEI 926
CP PGC+G GHV F H LSGCPL Q K ++S+ + + K G ++
Sbjct: 554 CPTPGCDGSGHVTGKFTAHHCLSGCPLAERNQSRLKAELSDSEASARKKNLSGFSPRKKP 613
Query: 927 RH 928
RH
Sbjct: 614 RH 615
Score = 50.4 bits (119), Expect = 9e-06
Identities = 19/27 (70%), Positives = 21/27 (77%)
Query: 367 KCPIPGCDGTGHVTGLYPHHRSLSGCP 393
KCP PGCDG+GHVTG + H LSGCP
Sbjct: 553 KCPTPGCDGSGHVTGKFTAHHCLSGCP 579
Score = 47.8 bits (112), Expect = 6e-05
Identities = 30/84 (35%), Positives = 34/84 (40%), Gaps = 18/84 (21%)
Query: 369 PIPGCDGTGH-----VTGLYPHHRSLSGCPHKVRVPLEILAMHENVL--------KCPTP 415
P C TGH + P S GCP PL ++ KCPTP
Sbjct: 503 PAGWCSKTGHPLQPPLGPREPSSASPGGCP-----PLSYRSLPHTRTSKYSFHHRKCPTP 557
Query: 416 GCTGRGHVNSNRNTHRSLSGCPIA 439
GC G GHV H LSGCP+A
Sbjct: 558 GCDGSGHVTGKFTAHHCLSGCPLA 581
>gi|117938330 l(3)mbt-like isoform II [Homo sapiens]
Length = 738
Score = 61.6 bits (148), Expect = 4e-09
Identities = 37/97 (38%), Positives = 49/97 (50%), Gaps = 11/97 (11%)
Query: 725 PTPGCDGSGH-----VTGNYASHRSVSGCP-LADKTLKSLMAA--NSQELKCPTPGCDGS 776
P C +GH + S S GCP L+ ++L + + KCPTPGCDGS
Sbjct: 503 PAGWCSKTGHPLQPPLGPREPSSASPGGCPPLSYRSLPHTRTSKYSFHHRKCPTPGCDGS 562
Query: 777 GHVTGNYASHRSLSGCPRARKGGVKMTPTKEEKEDPE 813
GHVTG + +H LSGCP A + ++ K E D E
Sbjct: 563 GHVTGKFTAHHCLSGCPLAERNQSRL---KAELSDSE 596
Score = 60.1 bits (144), Expect = 1e-08
Identities = 60/214 (28%), Positives = 89/214 (41%), Gaps = 58/214 (27%)
Query: 724 CPTPGCDGSGHVTGNYASHRSVSGCPLADKTLKSLMAANSQELKCPTPGCDGSGHVTGNY 783
CPTPGCDGSGHVTG + +H +SGCPLA++ N LK + S
Sbjct: 554 CPTPGCDGSGHVTGKFTAHHCLSGCPLAER--------NQSRLKAELSDSEAS------- 598
Query: 784 ASHRSLSGCPRARK----GGVKMTP--TKEEKEDPELKCPVIGCDGQGHISGKYTSHRTA 837
A ++LSG +K G + P K +ED + P + H++
Sbjct: 599 ARKKNLSGFSPRKKPRHHGRIGRPPKYRKIPQEDFQTLTPDV-------------VHQSL 645
Query: 838 SGCPLAAKRQKENPLNGASLSWKLNKQELPHCP-LPGCNGLG-------HVNNVFVTHRS 889
L+A +P S+ W+ HC LPG G+ ++ VF ++
Sbjct: 646 FMSALSA-----HPDRSLSVCWE------QHCKLLPGVAGISASTVAKWTIDEVFGFVQT 694
Query: 890 LSGCPLNAQVIK-----KGKVSEELMTIKLKATG 918
L+GC A++ K K +V + LK G
Sbjct: 695 LTGCEDQARLFKDEVRCKCRVGDRAGVTVLKTAG 728
Score = 57.0 bits (136), Expect = 9e-08
Identities = 31/84 (36%), Positives = 40/84 (47%), Gaps = 6/84 (7%)
Query: 769 PTPGCDGSGH-----VTGNYASHRSLSGCPRARKGGVKMTPTKEEKEDPELKCPVIGCDG 823
P C +GH + S S GCP + T T + KCP GCDG
Sbjct: 503 PAGWCSKTGHPLQPPLGPREPSSASPGGCPPLSYRSLPHTRTSKYSFHHR-KCPTPGCDG 561
Query: 824 QGHISGKYTSHRTASGCPLAAKRQ 847
GH++GK+T+H SGCPLA + Q
Sbjct: 562 SGHVTGKFTAHHCLSGCPLAERNQ 585
Score = 51.6 bits (122), Expect = 4e-06
Identities = 38/122 (31%), Positives = 52/122 (42%), Gaps = 19/122 (15%)
Query: 817 PVIGCDGQGH-----ISGKYTSHRTASGCPLAAKRQKENPLNGASLSW-KLNKQELPH-- 868
P C GH + + S + GCP PL+ SL + +K H
Sbjct: 503 PAGWCSKTGHPLQPPLGPREPSSASPGGCP---------PLSYRSLPHTRTSKYSFHHRK 553
Query: 869 CPLPGCNGLGHVNNVFVTHRSLSGCPL--NAQVIKKGKVSEELMTIKLKATGGIESDEEI 926
CP PGC+G GHV F H LSGCPL Q K ++S+ + + K G ++
Sbjct: 554 CPTPGCDGSGHVTGKFTAHHCLSGCPLAERNQSRLKAELSDSEASARKKNLSGFSPRKKP 613
Query: 927 RH 928
RH
Sbjct: 614 RH 615
Score = 50.4 bits (119), Expect = 9e-06
Identities = 19/27 (70%), Positives = 21/27 (77%)
Query: 367 KCPIPGCDGTGHVTGLYPHHRSLSGCP 393
KCP PGCDG+GHVTG + H LSGCP
Sbjct: 553 KCPTPGCDGSGHVTGKFTAHHCLSGCP 579
Score = 47.8 bits (112), Expect = 6e-05
Identities = 30/84 (35%), Positives = 34/84 (40%), Gaps = 18/84 (21%)
Query: 369 PIPGCDGTGH-----VTGLYPHHRSLSGCPHKVRVPLEILAMHENVL--------KCPTP 415
P C TGH + P S GCP PL ++ KCPTP
Sbjct: 503 PAGWCSKTGHPLQPPLGPREPSSASPGGCP-----PLSYRSLPHTRTSKYSFHHRKCPTP 557
Query: 416 GCTGRGHVNSNRNTHRSLSGCPIA 439
GC G GHV H LSGCP+A
Sbjct: 558 GCDGSGHVTGKFTAHHCLSGCPLA 581
>gi|5901962 MYST histone acetyltransferase 2 [Homo sapiens]
Length = 611
Score = 47.8 bits (112), Expect = 6e-05
Identities = 17/28 (60%), Positives = 22/28 (78%)
Query: 766 LKCPTPGCDGSGHVTGNYASHRSLSGCP 793
+KCPTPGC+ GH+TG + H S+SGCP
Sbjct: 183 MKCPTPGCNSLGHLTGKHERHFSISGCP 210
Score = 47.0 bits (110), Expect = 9e-05
Identities = 17/27 (62%), Positives = 21/27 (77%)
Query: 724 CPTPGCDGSGHVTGNYASHRSVSGCPL 750
CPTPGC+ GH+TG + H S+SGCPL
Sbjct: 185 CPTPGCNSLGHLTGKHERHFSISGCPL 211
Score = 46.2 bits (108), Expect = 2e-04
Identities = 41/172 (23%), Positives = 71/172 (41%), Gaps = 35/172 (20%)
Query: 814 LKCPVIGCDGQGHISGKYTSHRTASGCPLAAKRQKENPLNGASLSWKLNKQELPHCPLPG 873
+KCP GC+ GH++GK+ H + SGCPL + A K ++ +
Sbjct: 183 MKCPTPGCNSLGHLTGKHERHFSISGCPLYHNLSADECKVRAQSRDKQIEERM------- 235
Query: 874 CNGLGHVNNVFVTHRSLSGCPLNAQVIKKGKVSEELMTIKLKATGGIESDEEIRHLDE-- 931
L H + H + P Q+ K KV+E ++ K G+ +++ ++++
Sbjct: 236 ---LSHRQDDNNRHATRHQAPTERQLRYKEKVAE----LRKKRNSGLSKEQKEKYMEHRQ 288
Query: 932 ---EIKELNESNLKIEADM----------------MKLQTQITSMESNLKTI 964
+E NL E D+ ++LQ QIT + +KTI
Sbjct: 289 TYGNTREPLLENLTSEYDLDLFRRAQARASEDLEKLRLQGQITEGSNMIKTI 340
Score = 45.4 bits (106), Expect = 3e-04
Identities = 20/44 (45%), Positives = 26/44 (59%), Gaps = 8/44 (18%)
Query: 358 SPRPEKRE--------TKCPIPGCDGTGHVTGLYPHHRSLSGCP 393
S RP++R KCP PGC+ GH+TG + H S+SGCP
Sbjct: 167 SHRPKRRRFHESYNFNMKCPTPGCNSLGHLTGKHERHFSISGCP 210
Score = 43.5 bits (101), Expect = 0.001
Identities = 15/29 (51%), Positives = 19/29 (65%)
Query: 410 LKCPTPGCTGRGHVNSNRNTHRSLSGCPI 438
+KCPTPGC GH+ H S+SGCP+
Sbjct: 183 MKCPTPGCNSLGHLTGKHERHFSISGCPL 211
>gi|158138528 l(3)mbt-like 4 [Homo sapiens]
Length = 623
Score = 46.6 bits (109), Expect = 1e-04
Identities = 19/34 (55%), Positives = 22/34 (64%), Gaps = 1/34 (2%)
Query: 724 CPTPGCDGSGHVTG-NYASHRSVSGCPLADKTLK 756
CPTPGC G GH+ G Y+ H S GCP +D LK
Sbjct: 379 CPTPGCRGIGHIRGPRYSGHHSAFGCPYSDMNLK 412
Score = 40.8 bits (94), Expect = 0.007
Identities = 16/27 (59%), Positives = 18/27 (66%), Gaps = 1/27 (3%)
Query: 768 CPTPGCDGSGHVTG-NYASHRSLSGCP 793
CPTPGC G GH+ G Y+ H S GCP
Sbjct: 379 CPTPGCRGIGHIRGPRYSGHHSAFGCP 405
Score = 39.3 bits (90), Expect = 0.020
Identities = 25/70 (35%), Positives = 29/70 (41%), Gaps = 15/70 (21%)
Query: 369 PIPGCDGTGHVTGLYPHHRSLSGCPHKVRVPLEILAMHENVLKCPTPGCTGRGHVNSNR- 427
PI CD TGH P +V L + CPTPGC G GH+ R
Sbjct: 350 PIGWCDVTGH--------------PLEVPQRTNDLKILPGQAVCPTPGCRGIGHIRGPRY 395
Query: 428 NTHRSLSGCP 437
+ H S GCP
Sbjct: 396 SGHHSAFGCP 405
Score = 38.5 bits (88), Expect = 0.033
Identities = 26/101 (25%), Positives = 44/101 (43%), Gaps = 7/101 (6%)
Query: 869 CPLPGCNGLGHVNNV-FVTHRSLSGCPLNAQVIKKGKVSEELMTIKLKATGGIESDEEIR 927
CP PGC G+GH+ + H S GCP + +KK + + + +A +ESD
Sbjct: 379 CPTPGCRGIGHIRGPRYSGHHSAFGCPYSDMNLKKEATLHDRLREQTQA--NLESDSS-- 434
Query: 928 HLDEEIKELNESNLKIEADMMKLQTQITSMESNLKTIEEEN 968
+ K L N + + + Q ++ LK +E+
Sbjct: 435 --HSKSKSLCSLNFNGKHEKVNSQPRLVQQAKCLKIKGKED 473
Score = 37.7 bits (86), Expect = 0.057
Identities = 32/120 (26%), Positives = 52/120 (43%), Gaps = 21/120 (17%)
Query: 816 CPVIGCDGQGHISG-KYTSHRTASGCPLAAKRQKENPLNGASLSWKLNKQELPHCPLPGC 874
CP GC G GHI G +Y+ H +A GCP + K+ A+L +L +Q +
Sbjct: 379 CPTPGCRGIGHIRGPRYSGHHSAFGCPYSDMNLKKE----ATLHDRLREQTQANLESDSS 434
Query: 875 NGLGHVNNVFVTHRSLSGCPLN-----AQVIKKGKVSEELMTIKLKATGGIESDEEIRHL 929
+ +S S C LN +V + ++ ++ +K+K I+ D R L
Sbjct: 435 HS-----------KSKSLCSLNFNGKHEKVNSQPRLVQQAKCLKIKGKEDIDLDNLFRVL 483
Score = 37.4 bits (85), Expect = 0.074
Identities = 15/28 (53%), Positives = 17/28 (60%), Gaps = 1/28 (3%)
Query: 368 CPIPGCDGTGHVTG-LYPHHRSLSGCPH 394
CP PGC G GH+ G Y H S GCP+
Sbjct: 379 CPTPGCRGIGHIRGPRYSGHHSAFGCPY 406
>gi|16445033 ACRC protein [Homo sapiens]
Length = 691
Score = 46.2 bits (108), Expect = 2e-04
Identities = 41/165 (24%), Positives = 75/165 (45%), Gaps = 13/165 (7%)
Query: 147 ENLNDSGIQSLKAESDEADECFLIHSDDGRDKIDDSQPPFCSSDDNESNSESA------- 199
+N ND + ++ EA + S+ D DDS+ P +SDD+E+ +++
Sbjct: 131 DNGNDLEVPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPD 190
Query: 200 ENGWDSGSNFSEETKPPRVPKYVLTDHKKDLLEVPEIKTEGDKFIPCENRCDSETERKDP 259
+N DS + S+++ + D K D +VP+ ++ D +P ++ DSE D
Sbjct: 191 DNSDDSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSD-DSDVPDDSSDDSEAP-DDS 248
Query: 260 QNALAEPLDGNAQPSFPDVEEEDSESLAVMTEEGSDLEKAKGNLS 304
+ P D + PD +DSE+ ++ SD +A + S
Sbjct: 249 SDDSEAPDDSSDDSEAPDDSSDDSEA----PDDSSDDSEASDDSS 289
Score = 43.9 bits (102), Expect = 8e-04
Identities = 84/378 (22%), Positives = 138/378 (36%), Gaps = 49/378 (12%)
Query: 61 PRHYSPKADCQEDRSDRTE--DDGPLETHGHSTAEEIMIKPMDESLLSTAQENSSRKEDR 118
P S ++ +D SD +E DD ++ + P D S ++ +NS D
Sbjct: 149 PDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPDDNSD-DSSDDNSDDSSDD 207
Query: 119 YSCYQELMVKSLMHLGKFEKNVSVQTVSENLNDSGIQSLKAESDEADECFLIHSDDGRDK 178
S ++ +K+ ++ +DS + ++ EA + S+ D
Sbjct: 208 NSDDSDV---------PDDKSDDSDVPDDSSDDSDVPDDSSDDSEAPDDSSDDSEAPDDS 258
Query: 179 IDDSQPPFCSSDDNESNSESAENGWDS-GSNFSEETKPPRVPKYVLTDHKKDLLEVPEIK 237
DDS+ P SSDD+E+ +S+++ S S+ E D K D +VPE K
Sbjct: 259 SDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEASDDSSDDSEAPDDKSDDSDVPEDK 318
Query: 238 TEGDKFIPCENRCDSETERKDPQNALAEPLDGNAQPSFPD---------VEEEDSESLAV 288
++ D +P +N D E AE L Q + + V + DS A
Sbjct: 319 SD-DSDVPDDNSDDLEVP------VPAEDLCNEGQIASDEEELVEAAAAVSQHDSSDDAG 371
Query: 289 MTEEGSDLEK----AKGNLSLLEQAIALQAERGCVFHNTYKELDRFLLEHLAGERRQTKV 344
+ G +L K + N + E+ + + E V + K + +RQTK
Sbjct: 372 EQDLGENLSKPPSDPEANPEVSERKLPTEEEPAPVVEQSGKRKSKTKTIVEPPRKRQTKT 431
Query: 345 IDMGGRQIFNNKHSPRPEKRETKC-----PIPGCDGTGHVTGLYPHHRSLSGCPHKVRVP 399
N P P KR+TK P+ + P H+ G K
Sbjct: 432 ---------KNIVEP-PRKRQTKTKNIVEPLRKRKAKTKNVSVTPGHKK-RGPSKKKPGA 480
Query: 400 LEILAMHENVLKCPTPGC 417
++ KC PGC
Sbjct: 481 AKVEKRKTRTPKCKVPGC 498
Score = 33.5 bits (75), Expect = 1.1
Identities = 31/135 (22%), Positives = 56/135 (41%), Gaps = 27/135 (20%)
Query: 162 DEADECF----------LIHSDDGRDKID--DSQPPFCSSDDNESNSESAENGWDSGSNF 209
DE+ EC ++ SDD D + D + P +SDD+E+ +++++ N
Sbjct: 104 DESPECCHVKPAIQEPPIVISDDDNDDDNGNDLEVPDDNSDDSEAPDDNSDDSEAPDDNS 163
Query: 210 SEETKPPRVPKYVLTDHKKDLLEVPEIKTEGDKFIPCENRCDSETERKDPQNALAEPLDG 269
+ P D D E P+ ++ D +P +N DS + D + D
Sbjct: 164 DDSEAP---------DDNSDDSEAPDDNSD-DSDVPDDNSDDSSDDNSDDSSD-----DN 208
Query: 270 NAQPSFPDVEEEDSE 284
+ PD + +DS+
Sbjct: 209 SDDSDVPDDKSDDSD 223
>gi|31982906 cingulin-like 1 [Homo sapiens]
Length = 1302
Score = 44.3 bits (103), Expect = 6e-04
Identities = 39/159 (24%), Positives = 74/159 (46%), Gaps = 18/159 (11%)
Query: 901 KKGKVSEELMTIKLKATGGIESDEEIRHLDEEIKELNESNLKIEADMMKLQTQITSMESN 960
K V E++ T+K +A G + + + + E+K+L E K+ ++ +LQ Q+ N
Sbjct: 577 KVNLVFEKIQTLKSRAAGSAQGNNQACNSTSEVKDLLEQKSKLTIEVAELQRQLQLEVKN 636
Query: 961 LKTIEEENKLIEQNNESL-------LKELAGLSQALISSLADI-----QLPQMGPISEQ- 1007
+ I+EE + + N E L ++E + L Q L S ++ +L Q+ EQ
Sbjct: 637 QQNIKEERERMRANLEELRSQHNEKVEENSTLQQRLEESEGELRKNLEELFQVKMEREQH 696
Query: 1008 -----NFEAYVNTLTDMYSNLERDYSPECKALLESIKQA 1041
+ + ++ + D + +R E AL+E + QA
Sbjct: 697 QTEIRDLQDQLSEMHDELDSAKRSEDREKGALIEELLQA 735
>gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo
sapiens]
Length = 1939
Score = 41.2 bits (95), Expect = 0.005
Identities = 33/124 (26%), Positives = 59/124 (47%), Gaps = 5/124 (4%)
Query: 907 EELMTIKLKATGGIESDEEIRHLDEEIK-ELNESNLKIEADMMKLQTQITSMESNLKTIE 965
++L+ K++ I+ E +EEI EL K+E + +L+ I +E L +E
Sbjct: 910 DQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVE 969
Query: 966 EENKLIEQNNESLLKELAGLSQALISSLAD---IQLPQMGPISE-QNFEAYVNTLTDMYS 1021
+E E ++L +E+AGL + + + +Q + + Q E VNTLT +
Sbjct: 970 KEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQMEEDKVNTLTKAKT 1029
Query: 1022 NLER 1025
LE+
Sbjct: 1030 KLEQ 1033
Score = 30.4 bits (67), Expect = 9.1
Identities = 18/77 (23%), Positives = 38/77 (49%), Gaps = 6/77 (7%)
Query: 924 EEIRHLDEEIKELNESNLKIEADMMKLQTQITSMESNLKTIEEENKLIEQNNESLLKELA 983
+ + L E+I L K+E + +L+ +I + SN++T+ + E+ +L +L+
Sbjct: 1202 DSVAELGEQIDSLQRVKQKLEKEKSELKMEINDLASNMETVSKAKANFEKMCRTLEDQLS 1261
Query: 984 GL------SQALISSLA 994
+ Q LI+ L+
Sbjct: 1262 EIKTKEEEQQRLINELS 1278
>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
sapiens]
Length = 1938
Score = 40.8 bits (94), Expect = 0.007
Identities = 37/149 (24%), Positives = 73/149 (48%), Gaps = 12/149 (8%)
Query: 906 SEELMTIKLKA-TGGIESDEEI--------RHLDEEIKELNESNLKIEADMMKLQTQITS 956
S+ L+ K+K T +E +EE+ R+L+++ L +E + K++ + +
Sbjct: 915 SKILLEAKVKELTERLEEEEEMNSELVAKKRNLEDKCSSLKRDIDDLELTLTKVEKEKHA 974
Query: 957 MESNLKTIEEENKLIEQNNESLLKELAGLSQALISSLADIQLPQMGPISEQNFEAYVNTL 1016
E+ +K + EE +E+N L KE L +A +L D+Q+ + A +
Sbjct: 975 TENKVKNLSEEMTALEENISKLTKEKKSLQEAHQQTLDDLQVEEDKVNGLIKINAKLEQQ 1034
Query: 1017 T-DMYSNLERDYSPECKALLESIKQAVKG 1044
T D+ +LE++ + +A LE K+ ++G
Sbjct: 1035 TDDLEGSLEQE--KKLRADLERAKRKLEG 1061
Score = 32.7 bits (73), Expect = 1.8
Identities = 19/71 (26%), Positives = 35/71 (49%), Gaps = 3/71 (4%)
Query: 931 EEIKELNESNLKIEADMMKLQTQITSMESNLKTIEEENKLIEQNNESL---LKELAGLSQ 987
++++ L N ++ ++ L QI NL+ E+ KL+EQ L L+E+ G +
Sbjct: 1497 DQLETLRRENKNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLE 1556
Query: 988 ALISSLADIQL 998
S + +QL
Sbjct: 1557 HEESKILRVQL 1567
>gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens]
Length = 1684
Score = 40.4 bits (93), Expect = 0.009
Identities = 40/134 (29%), Positives = 61/134 (45%), Gaps = 17/134 (12%)
Query: 904 KVSEELMTIKLKATGGIESDEEIRHLDEEIKELN-------------ESNLKIEADMMK- 949
K +EL +K A + EI + +KELN E +KI+ +
Sbjct: 1140 KTMQELELVKKDAQQTTLMNMEIADYERLMKELNQKLTNKNNKIEDLEQEIKIQKQKQET 1199
Query: 950 LQTQITSMESNLKTIEEENKLIEQNNESLLKELAGLSQALISSLADIQLPQMGPI--SEQ 1007
LQ +ITS++S+++ EE+N I+Q KELA QA L +Q G + S+Q
Sbjct: 1200 LQEEITSLQSSVQQYEEKNTKIKQLLVKTKKELADSKQAETDHLI-LQASLKGELEASQQ 1258
Query: 1008 NFEAYVNTLTDMYS 1021
E Y L ++ S
Sbjct: 1259 QVEVYKIQLAEITS 1272
>gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]
Length = 2003
Score = 40.4 bits (93), Expect = 0.009
Identities = 40/146 (27%), Positives = 70/146 (47%), Gaps = 13/146 (8%)
Query: 908 ELMTIKLKATGGIESDEEIRHLDEEIKELNESNLKIEADM-------MKLQTQITSMESN 960
EL+ +L+A G E +E R + E K L + ++EA + KLQ + + E+
Sbjct: 946 ELVVSELEARVG-EEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAK 1004
Query: 961 LKTIEEENKLIEQNNESLLKELAGLSQAL--ISSLADIQLPQMGPISEQNFEAYVNTLTD 1018
+K EE+ L+E N L KE L L SS A + ++ +++ + Y T+ D
Sbjct: 1005 MKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLK-YEATIAD 1063
Query: 1019 MYSNLERDYSPECKALLESIKQAVKG 1044
M L ++ + + LE +K+ + G
Sbjct: 1064 MEDRLRKE--EKGRQELEKLKRRLDG 1087
>gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]
Length = 1995
Score = 40.4 bits (93), Expect = 0.009
Identities = 40/146 (27%), Positives = 70/146 (47%), Gaps = 13/146 (8%)
Query: 908 ELMTIKLKATGGIESDEEIRHLDEEIKELNESNLKIEADM-------MKLQTQITSMESN 960
EL+ +L+A G E +E R + E K L + ++EA + KLQ + + E+
Sbjct: 938 ELVVSELEARVG-EEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAK 996
Query: 961 LKTIEEENKLIEQNNESLLKELAGLSQAL--ISSLADIQLPQMGPISEQNFEAYVNTLTD 1018
+K EE+ L+E N L KE L L SS A + ++ +++ + Y T+ D
Sbjct: 997 MKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLK-YEATIAD 1055
Query: 1019 MYSNLERDYSPECKALLESIKQAVKG 1044
M L ++ + + LE +K+ + G
Sbjct: 1056 MEDRLRKE--EKGRQELEKLKRRLDG 1079
>gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]
Length = 2036
Score = 40.4 bits (93), Expect = 0.009
Identities = 40/146 (27%), Positives = 70/146 (47%), Gaps = 13/146 (8%)
Query: 908 ELMTIKLKATGGIESDEEIRHLDEEIKELNESNLKIEADM-------MKLQTQITSMESN 960
EL+ +L+A G E +E R + E K L + ++EA + KLQ + + E+
Sbjct: 979 ELVVSELEARVG-EEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAK 1037
Query: 961 LKTIEEENKLIEQNNESLLKELAGLSQAL--ISSLADIQLPQMGPISEQNFEAYVNTLTD 1018
+K EE+ L+E N L KE L L SS A + ++ +++ + Y T+ D
Sbjct: 1038 MKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLK-YEATIAD 1096
Query: 1019 MYSNLERDYSPECKALLESIKQAVKG 1044
M L ++ + + LE +K+ + G
Sbjct: 1097 MEDRLRKE--EKGRQELEKLKRRLDG 1120
>gi|229577185 epidermal growth factor receptor pathway substrate 15
isoform B [Homo sapiens]
Length = 582
Score = 40.0 bits (92), Expect = 0.011
Identities = 28/100 (28%), Positives = 50/100 (50%), Gaps = 1/100 (1%)
Query: 921 ESDEEIRHLDEEIKELNESNLKIEADMMKLQTQITSMESNLKTIEEENKLIEQNNESLLK 980
E DE+ L+E++KE+ + + + L+ ++TS ES + T EEE + L +
Sbjct: 86 ELDEQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQ 145
Query: 981 ELAGLSQALISSLADIQ-LPQMGPISEQNFEAYVNTLTDM 1019
E A L +++ S A ++ L Q S+Q + L +M
Sbjct: 146 ETAELEESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEM 185
>gi|4503593 epidermal growth factor receptor pathway substrate 15
isoform A [Homo sapiens]
Length = 896
Score = 40.0 bits (92), Expect = 0.011
Identities = 28/100 (28%), Positives = 50/100 (50%), Gaps = 1/100 (1%)
Query: 921 ESDEEIRHLDEEIKELNESNLKIEADMMKLQTQITSMESNLKTIEEENKLIEQNNESLLK 980
E DE+ L+E++KE+ + + + L+ ++TS ES + T EEE + L +
Sbjct: 400 ELDEQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQ 459
Query: 981 ELAGLSQALISSLADIQ-LPQMGPISEQNFEAYVNTLTDM 1019
E A L +++ S A ++ L Q S+Q + L +M
Sbjct: 460 ETAELEESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEM 499
>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
sapiens]
Length = 1939
Score = 40.0 bits (92), Expect = 0.011
Identities = 33/124 (26%), Positives = 58/124 (46%), Gaps = 5/124 (4%)
Query: 907 EELMTIKLKATGGIESDEEIRHLDEEIK-ELNESNLKIEADMMKLQTQITSMESNLKTIE 965
++L+ K++ I+ E +EEI EL K+E + +L+ I +E L +E
Sbjct: 910 DQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVE 969
Query: 966 EENKLIEQNNESLLKELAGLSQALISSLAD---IQLPQMGPISE-QNFEAYVNTLTDMYS 1021
+E E ++L +E+AGL + + + +Q + + Q E VNTLT
Sbjct: 970 KEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKI 1029
Query: 1022 NLER 1025
LE+
Sbjct: 1030 KLEQ 1033
Score = 32.0 bits (71), Expect = 3.1
Identities = 28/130 (21%), Positives = 62/130 (47%), Gaps = 13/130 (10%)
Query: 924 EEIRHLDEEIKELNESNLKIEADMMKLQTQITSMESNLKTIEEENKLIEQNNESLLKELA 983
+ + L E+I L K+E + +++ +I + SN++T+ + +E+ +L +L+
Sbjct: 1202 DSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLS 1261
Query: 984 GL------SQALISSL----ADIQLPQMGPISEQNFEAYVNTLTDMYSNLERDYSPECKA 1033
+ Q LI+ L A +Q + G S Q E +TL S ++ ++ + +
Sbjct: 1262 EIKTKEEEQQRLINDLTAQRARLQ-TESGEYSRQLDEK--DTLVSQLSRGKQAFTQQIEE 1318
Query: 1034 LLESIKQAVK 1043
L +++ +K
Sbjct: 1319 LKRQLEEEIK 1328
>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 40.0 bits (92), Expect = 0.011
Identities = 33/124 (26%), Positives = 58/124 (46%), Gaps = 5/124 (4%)
Query: 907 EELMTIKLKATGGIESDEEIRHLDEEIK-ELNESNLKIEADMMKLQTQITSMESNLKTIE 965
++L+ K++ I+ E +EEI EL K+E + +L+ I +E L +E
Sbjct: 912 DQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVE 971
Query: 966 EENKLIEQNNESLLKELAGLSQALISSLAD---IQLPQMGPISE-QNFEAYVNTLTDMYS 1021
+E E ++L +E+AGL + + + +Q + + Q E VNTLT
Sbjct: 972 KEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKI 1031
Query: 1022 NLER 1025
LE+
Sbjct: 1032 KLEQ 1035
>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 40.0 bits (92), Expect = 0.011
Identities = 33/124 (26%), Positives = 58/124 (46%), Gaps = 5/124 (4%)
Query: 907 EELMTIKLKATGGIESDEEIRHLDEEIK-ELNESNLKIEADMMKLQTQITSMESNLKTIE 965
++L+ K++ I+ E +EEI EL K+E + +L+ I +E L +E
Sbjct: 912 DQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVE 971
Query: 966 EENKLIEQNNESLLKELAGLSQALISSLAD---IQLPQMGPISE-QNFEAYVNTLTDMYS 1021
+E E ++L +E+AGL + + + +Q + + Q E VNTLT
Sbjct: 972 KEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKI 1031
Query: 1022 NLER 1025
LE+
Sbjct: 1032 KLEQ 1035
>gi|83715964 high-mobility group 20B [Homo sapiens]
Length = 317
Score = 39.3 bits (90), Expect = 0.020
Identities = 22/73 (30%), Positives = 38/73 (52%)
Query: 930 DEEIKELNESNLKIEADMMKLQTQITSMESNLKTIEEENKLIEQNNESLLKELAGLSQAL 989
+ E++ L + N+ E LQ SM S + +E+E L E+ +L ++L + QAL
Sbjct: 200 EAELRRLRKMNVAFEEQNAVLQRHTQSMSSARERLEQELALEERRTLALQQQLQAVRQAL 259
Query: 990 ISSLADIQLPQMG 1002
+S A + +P G
Sbjct: 260 TASFASLPVPGTG 272
>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal
[Homo sapiens]
Length = 1937
Score = 39.3 bits (90), Expect = 0.020
Identities = 24/84 (28%), Positives = 43/84 (51%), Gaps = 1/84 (1%)
Query: 907 EELMTIKLKATGGIESDEEIRHLDEEIK-ELNESNLKIEADMMKLQTQITSMESNLKTIE 965
E+L+ K++ I+ E +EEI EL K+E + +L+ I +E L +E
Sbjct: 909 EQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVE 968
Query: 966 EENKLIEQNNESLLKELAGLSQAL 989
+E E ++L +E+AGL + +
Sbjct: 969 KEKHATENKVKNLTEEMAGLDETI 992
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 38.5 bits (88), Expect = 0.033
Identities = 24/68 (35%), Positives = 35/68 (51%), Gaps = 7/68 (10%)
Query: 921 ESDEEIRHLDEE-------IKELNESNLKIEADMMKLQTQITSMESNLKTIEEENKLIEQ 973
E +E +HL E I+EL E + E+ KLQ + + E+ LK +EEE ++E
Sbjct: 926 EEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILED 985
Query: 974 NNESLLKE 981
N L KE
Sbjct: 986 QNCKLAKE 993
Score = 30.4 bits (67), Expect = 9.1
Identities = 21/90 (23%), Positives = 47/90 (52%), Gaps = 4/90 (4%)
Query: 896 NAQVIKKGKVSEELMTIKLKATGGIESDEEIRHLDEEIKELNESNLKIEADMMKLQTQIT 955
N Q +++ EE KL+ + ++ +++ L+EE L + N K+ + L+ +I
Sbjct: 944 NIQELEEQLEEEESARQKLQLEK-VTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIA 1002
Query: 956 SMESNLKTIEEENK---LIEQNNESLLKEL 982
+NL EE++K ++ +E+++ +L
Sbjct: 1003 EFTTNLTEEEEKSKSLAKLKNKHEAMITDL 1032
>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
sapiens]
Length = 1935
Score = 38.1 bits (87), Expect = 0.044
Identities = 29/109 (26%), Positives = 50/109 (45%), Gaps = 4/109 (3%)
Query: 921 ESDEEIRHLDEEIKELNESNLKIEADMMKLQTQITSMESNLKTIEEENKLIEQNNESLLK 980
E +E + +E EL K+E + +L+ I +E L +E+E E ++L +
Sbjct: 921 EMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTE 980
Query: 981 ELAGLSQALISSLAD---IQLPQMGPISE-QNFEAYVNTLTDMYSNLER 1025
E+AGL + + + +Q + + Q E VNTLT LE+
Sbjct: 981 EMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQ 1029
Score = 32.0 bits (71), Expect = 3.1
Identities = 31/132 (23%), Positives = 56/132 (42%), Gaps = 12/132 (9%)
Query: 920 IESDEEIRHLDEEIKELNESNLKIEADMMKLQTQITSMESNLKTIEEENKL----IEQNN 975
IE+ E ++ L + L K++AD+ +LQT++ + EE+ K
Sbjct: 1707 IETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMA 1766
Query: 976 ESLLKE------LAGLSQALISSLADIQ--LPQMGPISEQNFEAYVNTLTDMYSNLERDY 1027
E L KE L + + + ++ D+Q L + I+ + + + L LE +
Sbjct: 1767 EELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENEL 1826
Query: 1028 SPECKALLESIK 1039
E K ES+K
Sbjct: 1827 EAEQKRNAESVK 1838
>gi|46049114 M-phase phosphoprotein 1 [Homo sapiens]
Length = 1780
Score = 38.1 bits (87), Expect = 0.044
Identities = 26/105 (24%), Positives = 49/105 (46%), Gaps = 6/105 (5%)
Query: 921 ESDEEIRHLDEEIKELNESNLKIEADMMKLQTQITSMESNLKTIEEENKLIEQNNESLLK 980
E E ++ + K+LN LK++ ++ +L + M+ L+ EEE + Q E L +
Sbjct: 1163 EFQEHLQDSVKNTKDLNVKELKLKEEITQLTNNLQDMKHLLQLKEEEEETNRQETEKLKE 1222
Query: 981 ELAGLSQALISSLADIQLPQMGPISEQNFEAYVNTLTDMYSNLER 1025
EL+ S + AD+Q E+++ LTD +++
Sbjct: 1223 ELSASSARTQNLKADLQR------KEEDYADLKEKLTDAKKQIKQ 1261
Score = 33.5 bits (75), Expect = 1.1
Identities = 20/69 (28%), Positives = 38/69 (55%), Gaps = 4/69 (5%)
Query: 931 EEIKELNESNLKIEADMMKLQTQITSMESNLKTIEEENKLIEQ----NNESLLKELAGLS 986
EE KE+ +++ K + +L+ QI +++ +K ++EN +++ N + LLKE L
Sbjct: 1022 EECKEIVKASSKKSHQIEELEQQIEKLQAEVKGYKDENNRLKEKEHKNQDDLLKEKETLI 1081
Query: 987 QALISSLAD 995
Q L L +
Sbjct: 1082 QQLKEELQE 1090
>gi|197276602 microtubule-associated protein 4 isoform 5 [Homo
sapiens]
Length = 817
Score = 37.7 bits (86), Expect = 0.057
Identities = 87/413 (21%), Positives = 134/413 (32%), Gaps = 73/413 (17%)
Query: 430 HRSLSGCPIAAAE--KLAMSQDKNQLDSPQTGQCPDQAHRTSLVKQIEFNFPSQAITSPR 487
H+ L IA E + +S N + +P + P + + K + P++ TS
Sbjct: 395 HKQLKSAGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKT--KPLATTQPAKTSTSKA 452
Query: 488 ATVSKEQEK---------FGKVPFDYASFDAQVFGKRPLIQTVQGRKTPPFPESKHFPNP 538
T K K P AS V P V + P P P
Sbjct: 453 KTQPTSLPKQPAPTTIGGLNKKPMSLAS--GLVPAAPPKRPAVASARPSILPSKDVKPKP 510
Query: 539 VKFPNRLPSAGAHTQSPGRASSYSYGQCSEDT--HIAAAAAILNLSTRCREATDILSNKP 596
+ + P A P A + G S T AAA+ + R + +L KP
Sbjct: 511 IA-DAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKP 569
Query: 597 QSLHAKGAEIEVDE-------------NGTLDLSMKKNRILDKSAPLTS------SNTSI 637
++ +G EV + T SMKK L +AP T +
Sbjct: 570 TAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPM 629
Query: 638 PT-PSSSPF--------KTSSIL---------VNAAFYQALCDQEGWDTPINYSKTHGKT 679
P+ PS++PF K SS +A + + + G I + G+
Sbjct: 630 PSRPSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGRV 689
Query: 680 EEEKEKDPVS-------SLENLEEKKFPGEASIPSPKPKLHARDLKKELITCPTPGCDGS 732
+ + +K +S S N++ K G+ I S K KE D
Sbjct: 690 QIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNF------KEKAQAKVGSLDNV 743
Query: 733 GHVTGNYASHRSVSG-----CPLADKTLKSLMAANSQELKCPTPGCDGSGHVT 780
GH+ A G CP + ++ + E PT +GH T
Sbjct: 744 GHLPAGGAVKTEGGGSEAPLCPGPPAGEEPAISEAAPEAGAPTSASGLNGHPT 796
>gi|47519616 tropomyosin 2 (beta) isoform 2 [Homo sapiens]
Length = 284
Score = 37.7 bits (86), Expect = 0.057
Identities = 28/88 (31%), Positives = 42/88 (47%), Gaps = 5/88 (5%)
Query: 898 QVIKKGKVSEELMTIKLKATGGIESDEEIRHLDEEIKELNESNLKIEADMMKLQTQITSM 957
Q +K SEE + K + +EEI+ L+E++KE E + KL+ I +
Sbjct: 202 QALKSLMASEEEYSTKED-----KYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDL 256
Query: 958 ESNLKTIEEENKLIEQNNESLLKELAGL 985
E L + +EEN I Q + L EL L
Sbjct: 257 EETLASAKEENVEIHQTLDQTLLELNNL 284
Score = 32.3 bits (72), Expect = 2.4
Identities = 33/120 (27%), Positives = 48/120 (40%), Gaps = 29/120 (24%)
Query: 930 DEEIKELNESNLK--------IEADMMKLQTQITSMESNLKTIEEENKLIEQNNESLLKE 981
DEE EL E LK + ++ ++ +E L+ EE ++ E L +E
Sbjct: 137 DEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAESRARQLEEE 196
Query: 982 LAGLSQALISSLADIQLPQMGPISEQNFEAYVNTLTDMYSNLERDYSPECKALLESIKQA 1041
L + QAL S +A SE+ YS E Y E K L E +K+A
Sbjct: 197 LRTMDQALKSLMA----------SEEE-----------YSTKEDKYEEEIKLLEEKLKEA 235
Score = 31.2 bits (69), Expect = 5.3
Identities = 34/155 (21%), Positives = 69/155 (44%), Gaps = 28/155 (18%)
Query: 2 DAEAEDKTLRTRSKGTEVPMDSLIQELSVAYDCSMAKKRTAEDQALGVPVNKRKSL---- 57
DAEA+ +L R + E +D + L+ A ++ A++ G+ V + +++
Sbjct: 80 DAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEE 139
Query: 58 --------LMKPRHYSPKADCQ-----------EDRSDRTEDDGPL-ETHGHSTAEEIMI 97
L + +H + +D + E +R+E+ + E+ EE+
Sbjct: 140 KMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAESRARQLEEEL-- 197
Query: 98 KPMDESL--LSTAQENSSRKEDRYSCYQELMVKSL 130
+ MD++L L ++E S KED+Y +L+ + L
Sbjct: 198 RTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKL 232
Score = 30.4 bits (67), Expect = 9.1
Identities = 19/85 (22%), Positives = 39/85 (45%), Gaps = 6/85 (7%)
Query: 904 KVSEELMTIKLKATGGIESDEEIRHLDEEIKELNESNLKIEADMMKLQTQITSMESNLKT 963
++ EE ++ K G +++E+ E +KE E + E + + S+ ++
Sbjct: 38 QLEEEQQALQKKLKG---TEDEVEKYSESVKEAQEKLEQAEKKATDAEADVASLNRRIQL 94
Query: 964 IEEENKLIEQNNESLLKELAGLSQA 988
+EEE +++ E L L L +A
Sbjct: 95 VEEE---LDRAQERLATALQKLEEA 116
>gi|224922812 tropomyosin 2 (beta) isoform 3 [Homo sapiens]
Length = 231
Score = 37.7 bits (86), Expect = 0.057
Identities = 28/88 (31%), Positives = 42/88 (47%), Gaps = 5/88 (5%)
Query: 898 QVIKKGKVSEELMTIKLKATGGIESDEEIRHLDEEIKELNESNLKIEADMMKLQTQITSM 957
Q +K SEE + K + +EEI+ L+E++KE E + KL+ I +
Sbjct: 149 QALKSLMASEEEYSTKED-----KYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDL 203
Query: 958 ESNLKTIEEENKLIEQNNESLLKELAGL 985
E L + +EEN I Q + L EL L
Sbjct: 204 EETLASAKEENVEIHQTLDQTLLELNNL 231
Score = 32.3 bits (72), Expect = 2.4
Identities = 33/120 (27%), Positives = 48/120 (40%), Gaps = 29/120 (24%)
Query: 930 DEEIKELNESNLK--------IEADMMKLQTQITSMESNLKTIEEENKLIEQNNESLLKE 981
DEE EL E LK + ++ ++ +E L+ EE ++ E L +E
Sbjct: 84 DEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAESRARQLEEE 143
Query: 982 LAGLSQALISSLADIQLPQMGPISEQNFEAYVNTLTDMYSNLERDYSPECKALLESIKQA 1041
L + QAL S +A SE+ YS E Y E K L E +K+A
Sbjct: 144 LRTMDQALKSLMA----------SEEE-----------YSTKEDKYEEEIKLLEEKLKEA 182
>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
sapiens]
Length = 1940
Score = 37.7 bits (86), Expect = 0.057
Identities = 32/124 (25%), Positives = 57/124 (45%), Gaps = 5/124 (4%)
Query: 907 EELMTIKLKATGGIESDEEIRHLDEEIK-ELNESNLKIEADMMKLQTQITSMESNLKTIE 965
++L+ K + I+ E +EEI EL K+E + +L+ I +E L +E
Sbjct: 907 DQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVE 966
Query: 966 EENKLIEQNNESLLKELAGLSQALISSLAD---IQLPQMGPISE-QNFEAYVNTLTDMYS 1021
+E E ++L +EL+GL + + + +Q + + Q E VN+L S
Sbjct: 967 KEKHATENKVKNLTEELSGLDETIAKLTREKKALQEAHQQALDDLQAEEDKVNSLNKTKS 1026
Query: 1022 NLER 1025
LE+
Sbjct: 1027 KLEQ 1030
Score = 32.3 bits (72), Expect = 2.4
Identities = 30/132 (22%), Positives = 59/132 (44%), Gaps = 12/132 (9%)
Query: 920 IESDEEIRHLDEEIKELNESNLKIEADMMKLQTQITSMESNLKTIEEENKL----IEQNN 975
++S+E ++ L + L + K+E D+M+LQ+++ + + EE+ K
Sbjct: 1708 LDSNERVQLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAKKAITDAAMMA 1767
Query: 976 ESLLKE------LAGLSQALISSLADIQ--LPQMGPISEQNFEAYVNTLTDMYSNLERDY 1027
E L KE L + + L ++ D+Q L + ++ + + + L LE +
Sbjct: 1768 EELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLETRIRELEFEL 1827
Query: 1028 SPECKALLESIK 1039
E K ES+K
Sbjct: 1828 EGEQKKNTESVK 1839
>gi|157738615 coiled-coil alpha-helical rod protein 1 isoform 1 [Homo
sapiens]
Length = 871
Score = 37.7 bits (86), Expect = 0.057
Identities = 32/132 (24%), Positives = 62/132 (46%), Gaps = 19/132 (14%)
Query: 924 EEIRHLDEEIKELNESNL----KIEADMMKLQ----------TQITSMESNLKTIEEENK 969
+E+R L+EE++ L E++L ++EA M+L+ + + + L E K
Sbjct: 188 QELRRLEEEVRLLRETSLQQKMRLEAQAMELEALARAEKAGRAEAEGLRAALAGAEVVRK 247
Query: 970 LIEQNNESLLKELAGLSQALISSLADIQLPQMGPISEQNFEAYVNTLTDMYSNLERDYSP 1029
+E+ ++ L+E+ L Q +SSL + ++ + L S+LE +
Sbjct: 248 NLEEGSQRELEEVQRLHQEQLSSLTQAHEEALSSLTSK-----AEGLEKSLSSLETRRAG 302
Query: 1030 ECKALLESIKQA 1041
E K L E+ ++A
Sbjct: 303 EAKELAEAQREA 314
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.128 0.372
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 44,298,290
Number of Sequences: 37866
Number of extensions: 2278699
Number of successful extensions: 8870
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 111
Number of HSP's successfully gapped in prelim test: 244
Number of HSP's that attempted gapping in prelim test: 7585
Number of HSP's gapped (non-prelim): 1406
length of query: 1047
length of database: 18,247,518
effective HSP length: 113
effective length of query: 934
effective length of database: 13,968,660
effective search space: 13046728440
effective search space used: 13046728440
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.