Search of human proteins with 7661918

Search of human proteins with 7661918

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|7661918 MAD2L1 binding protein isoform 2 [Homo sapiens]
         (274 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|7661918 MAD2L1 binding protein isoform 2 [Homo sapiens]            560   e-160
gi|51243063 MAD2L1 binding protein isoform 1 [Homo sapiens]           534   e-152
gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens]         30   1.7  
gi|239787821 syncoilin, intermediate filament 1 isoform 2 [Homo ...    29   3.9  
gi|166706887 syncoilin, intermediate filament 1 isoform 1 [Homo ...    29   3.9  
gi|18644886 forkhead box P1 isoform 1 [Homo sapiens]                   29   3.9  
gi|222144249 dynein heavy chain domain 1 isoform 1 [Homo sapiens]      29   5.1  
gi|239752100 PREDICTED: hypothetical protein [Homo sapiens]            29   5.1  
gi|239746604 PREDICTED: similar to Keratin-associated protein 10...    29   5.1  
gi|154759251 keratin associated protein 10-9 [Homo sapiens]            29   5.1  
gi|108860697 zinc finger protein 592 [Homo sapiens]                    29   5.1  
gi|153945846 inositol 1,4,5-triphosphate receptor, type 3 [Homo ...    28   6.6  
gi|31581524 cordon-bleu homolog [Homo sapiens]                         28   6.6  
gi|63053515 keratin associated protein 10-3 [Homo sapiens]             28   6.6  
gi|148612853 ATP-binding cassette, sub-family F (GCN20), member ...    28   6.6  
gi|158508542 kelch-like 33 [Homo sapiens]                              28   8.6  
gi|166197668 CD5 molecule [Homo sapiens]                               28   8.6  

>gi|7661918 MAD2L1 binding protein isoform 2 [Homo sapiens]
          Length = 274

 Score =  560 bits (1442), Expect = e-160
 Identities = 274/274 (100%), Positives = 274/274 (100%)

Query: 1   MAAPEAEVLSSAAVPDLEWYEKSEETHASQIELLETSSTQEPLNASEAFCPRDCMVPVVF 60
           MAAPEAEVLSSAAVPDLEWYEKSEETHASQIELLETSSTQEPLNASEAFCPRDCMVPVVF
Sbjct: 1   MAAPEAEVLSSAAVPDLEWYEKSEETHASQIELLETSSTQEPLNASEAFCPRDCMVPVVF 60

Query: 61  PGPVSQEGCCQFTCELLKHIMYQRQQLPLPYEQLKHFYRKPSPQAEEMLKKKPRATTEVS 120
           PGPVSQEGCCQFTCELLKHIMYQRQQLPLPYEQLKHFYRKPSPQAEEMLKKKPRATTEVS
Sbjct: 61  PGPVSQEGCCQFTCELLKHIMYQRQQLPLPYEQLKHFYRKPSPQAEEMLKKKPRATTEVS 120

Query: 121 SRKCQQALAELESVLSHLEDFFARTLVPRVLILLGGNALSPKEFYELDLSLLAPYSVDQS 180
           SRKCQQALAELESVLSHLEDFFARTLVPRVLILLGGNALSPKEFYELDLSLLAPYSVDQS
Sbjct: 121 SRKCQQALAELESVLSHLEDFFARTLVPRVLILLGGNALSPKEFYELDLSLLAPYSVDQS 180

Query: 181 LSTAACLRRLFRAIFMADAFSELQAPPLMGTVVMAQGHRNCGEDWFRPKLNYRVPSRGHK 240
           LSTAACLRRLFRAIFMADAFSELQAPPLMGTVVMAQGHRNCGEDWFRPKLNYRVPSRGHK
Sbjct: 181 LSTAACLRRLFRAIFMADAFSELQAPPLMGTVVMAQGHRNCGEDWFRPKLNYRVPSRGHK 240

Query: 241 LTVTLSCGRPSIRTTAWEDYIWFQAPVTFKGFRE 274
           LTVTLSCGRPSIRTTAWEDYIWFQAPVTFKGFRE
Sbjct: 241 LTVTLSCGRPSIRTTAWEDYIWFQAPVTFKGFRE 274


>gi|51243063 MAD2L1 binding protein isoform 1 [Homo sapiens]
          Length = 306

 Score =  534 bits (1376), Expect = e-152
 Identities = 260/263 (98%), Positives = 261/263 (99%)

Query: 12  AAVPDLEWYEKSEETHASQIELLETSSTQEPLNASEAFCPRDCMVPVVFPGPVSQEGCCQ 71
           A + DLEWYEKSEETHASQIELLETSSTQEPLNASEAFCPRDCMVPVVFPGPVSQEGCCQ
Sbjct: 44  AEIIDLEWYEKSEETHASQIELLETSSTQEPLNASEAFCPRDCMVPVVFPGPVSQEGCCQ 103

Query: 72  FTCELLKHIMYQRQQLPLPYEQLKHFYRKPSPQAEEMLKKKPRATTEVSSRKCQQALAEL 131
           FTCELLKHIMYQRQQLPLPYEQLKHFYRKPSPQAEEMLKKKPRATTEVSSRKCQQALAEL
Sbjct: 104 FTCELLKHIMYQRQQLPLPYEQLKHFYRKPSPQAEEMLKKKPRATTEVSSRKCQQALAEL 163

Query: 132 ESVLSHLEDFFARTLVPRVLILLGGNALSPKEFYELDLSLLAPYSVDQSLSTAACLRRLF 191
           ESVLSHLEDFFARTLVPRVLILLGGNALSPKEFYELDLSLLAPYSVDQSLSTAACLRRLF
Sbjct: 164 ESVLSHLEDFFARTLVPRVLILLGGNALSPKEFYELDLSLLAPYSVDQSLSTAACLRRLF 223

Query: 192 RAIFMADAFSELQAPPLMGTVVMAQGHRNCGEDWFRPKLNYRVPSRGHKLTVTLSCGRPS 251
           RAIFMADAFSELQAPPLMGTVVMAQGHRNCGEDWFRPKLNYRVPSRGHKLTVTLSCGRPS
Sbjct: 224 RAIFMADAFSELQAPPLMGTVVMAQGHRNCGEDWFRPKLNYRVPSRGHKLTVTLSCGRPS 283

Query: 252 IRTTAWEDYIWFQAPVTFKGFRE 274
           IRTTAWEDYIWFQAPVTFKGFRE
Sbjct: 284 IRTTAWEDYIWFQAPVTFKGFRE 306


>gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens]
          Length = 2115

 Score = 30.4 bits (67), Expect = 1.7
 Identities = 21/67 (31%), Positives = 35/67 (52%), Gaps = 2/67 (2%)

Query: 67   EGCCQFTCELLKHIMYQRQQLPLPYEQLKHFYRKPSPQAEEMLKKKPRATTEVSSRKCQQ 126
            EG      E  +    +RQ+L    EQL+ F R+ + Q EE+ KK   A ++ +S+  QQ
Sbjct: 1513 EGAKVKVLEERQRFQEERQKLTAQVEQLEVFQREQTKQVEELSKK--LADSDQASKVQQQ 1570

Query: 127  ALAELES 133
             L  +++
Sbjct: 1571 KLKAVQA 1577


>gi|239787821 syncoilin, intermediate filament 1 isoform 2 [Homo
           sapiens]
          Length = 476

 Score = 29.3 bits (64), Expect = 3.9
 Identities = 41/165 (24%), Positives = 65/165 (39%), Gaps = 37/165 (22%)

Query: 35  ETSSTQEPLNASEAFCPRDCMVPVVFPGPVSQEGCCQFTCE-----------------LL 77
           ET   +E L   EA  P + +  V  PG   +  C + T E                   
Sbjct: 75  ETEKAEEALYIEEAMQPDEAL-HVEEPGNPEETVCVEETTEPDRIQFVEGPVEPGKPTSP 133

Query: 78  KHIMYQ-----RQQLPLPYEQLKHFYRKPSPQAEEMLKKKPRATTEVSSRKCQQALAELE 132
           +H++Y+     R +   P E L+    + SP  EE L  +     E   ++C QA+A+LE
Sbjct: 134 EHVVYEGETVTRAEKSNPEESLR---AEQSPSVEENLSIEDLELLEGRFQQCVQAVAQLE 190

Query: 133 SVLSHLEDFFARTLVPRVLILLGGNALSPKEFYELDLSLLAPYSV 177
                      R  +   L+LL   AL  +E  ++   +LA Y +
Sbjct: 191 E---------ERDQLIHELVLLREPAL--QEVQQVHQDILAAYKL 224


>gi|166706887 syncoilin, intermediate filament 1 isoform 1 [Homo
           sapiens]
          Length = 482

 Score = 29.3 bits (64), Expect = 3.9
 Identities = 41/165 (24%), Positives = 65/165 (39%), Gaps = 37/165 (22%)

Query: 35  ETSSTQEPLNASEAFCPRDCMVPVVFPGPVSQEGCCQFTCE-----------------LL 77
           ET   +E L   EA  P + +  V  PG   +  C + T E                   
Sbjct: 75  ETEKAEEALYIEEAMQPDEAL-HVEEPGNPEETVCVEETTEPDRIQFVEGPVEPGKPTSP 133

Query: 78  KHIMYQ-----RQQLPLPYEQLKHFYRKPSPQAEEMLKKKPRATTEVSSRKCQQALAELE 132
           +H++Y+     R +   P E L+    + SP  EE L  +     E   ++C QA+A+LE
Sbjct: 134 EHVVYEGETVTRAEKSNPEESLR---AEQSPSVEENLSIEDLELLEGRFQQCVQAVAQLE 190

Query: 133 SVLSHLEDFFARTLVPRVLILLGGNALSPKEFYELDLSLLAPYSV 177
                      R  +   L+LL   AL  +E  ++   +LA Y +
Sbjct: 191 E---------ERDQLIHELVLLREPAL--QEVQQVHQDILAAYKL 224


>gi|18644886 forkhead box P1 isoform 1 [Homo sapiens]
          Length = 677

 Score = 29.3 bits (64), Expect = 3.9
 Identities = 18/66 (27%), Positives = 37/66 (56%), Gaps = 8/66 (12%)

Query: 77  LKHIMYQRQQLPLPYEQLKHFYRKPSPQAEEML------KKKPRATTEVSSRKC--QQAL 128
           L+ ++ Q+Q L L  +QL+ FY+K   Q +  L       K+P+   +V++++   QQ L
Sbjct: 126 LQVLLQQQQALMLQQQQLQEFYKKQQEQLQLQLLQQQHAGKQPKEQQQVATQQLAFQQQL 185

Query: 129 AELESV 134
            +++ +
Sbjct: 186 LQMQQL 191


>gi|222144249 dynein heavy chain domain 1 isoform 1 [Homo sapiens]
          Length = 4753

 Score = 28.9 bits (63), Expect = 5.1
 Identities = 24/101 (23%), Positives = 44/101 (43%), Gaps = 11/101 (10%)

Query: 75   ELLKHIMYQRQQLPLPYEQLKHFYRKPSPQAEEMLKKKPRATTEVSS-----------RK 123
            ++L   M  +   PL  E+L+     PSP     L++  +A +  S              
Sbjct: 1941 QVLAEPMTYKLMKPLVVEELQQVGLDPSPDILGSLEQLSQALSRASGILLLGPAGSGKTT 2000

Query: 124  CQQALAELESVLSHLEDFFARTLVPRVLILLGGNALSPKEF 164
            C  +L ++++ L+ +ED   +   P  +  L  + LSP+EF
Sbjct: 2001 CWHSLFKIQNRLAAMEDTSTQGCQPVEITHLYPSGLSPQEF 2041


>gi|239752100 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 312

 Score = 28.9 bits (63), Expect = 5.1
 Identities = 14/50 (28%), Positives = 21/50 (42%)

Query: 26  THASQIELLETSSTQEPLNASEAFCPRDCMVPVVFPGPVSQEGCCQFTCE 75
           T++ Q++    S  + P  A+    P  C+  V  P       CCQ  CE
Sbjct: 136 TNSWQVDDCPESCCEPPCCAASCCAPAPCLTLVCTPVSCVSSPCCQAACE 185


>gi|239746604 PREDICTED: similar to Keratin-associated protein 10-8
           [Homo sapiens]
          Length = 312

 Score = 28.9 bits (63), Expect = 5.1
 Identities = 14/50 (28%), Positives = 21/50 (42%)

Query: 26  THASQIELLETSSTQEPLNASEAFCPRDCMVPVVFPGPVSQEGCCQFTCE 75
           T++ Q++    S  + P  A+    P  C+  V  P       CCQ  CE
Sbjct: 136 TNSWQVDDCPESCCEPPCCAASCCAPAPCLTLVCTPVSCVSSPCCQAACE 185


>gi|154759251 keratin associated protein 10-9 [Homo sapiens]
          Length = 292

 Score = 28.9 bits (63), Expect = 5.1
 Identities = 14/46 (30%), Positives = 19/46 (41%)

Query: 30 QIELLETSSTQEPLNASEAFCPRDCMVPVVFPGPVSQEGCCQFTCE 75
          Q++    S  + P  A+    P  C+  V  P       CCQ TCE
Sbjct: 18 QVDDCPESCCEPPCCATSCCAPAPCLTLVCTPVSRVSSPCCQVTCE 63


>gi|108860697 zinc finger protein 592 [Homo sapiens]
          Length = 1267

 Score = 28.9 bits (63), Expect = 5.1
 Identities = 14/45 (31%), Positives = 27/45 (60%), Gaps = 1/45 (2%)

Query: 103  PQAEEMLKKKPRA-TTEVSSRKCQQALAELESVLSHLEDFFARTL 146
            P+A   ++ +PR   T  + ++CQ+ + + ES +SH++    RTL
Sbjct: 966  PEAHRRVEARPRLRNTGWTCQECQEWVPDRESYVSHMKKSHGRTL 1010


>gi|153945846 inositol 1,4,5-triphosphate receptor, type 3 [Homo
            sapiens]
          Length = 2671

 Score = 28.5 bits (62), Expect = 6.6
 Identities = 22/84 (26%), Positives = 33/84 (39%), Gaps = 19/84 (22%)

Query: 25   ETHASQIELLETSSTQEPLNASEAFCPRDCMVPVVFPGPVSQEGCCQFTCELLKHIMYQR 84
            E H SQIE++    + E                +VFP P    G CQF  E  KH ++  
Sbjct: 2118 ENHTSQIEIVRQDRSMEQ---------------IVFPVP----GICQFLTEETKHRLFTT 2158

Query: 85   QQLPLPYEQLKHFYRKPSPQAEEM 108
             +      ++  F+ + S    EM
Sbjct: 2159 TEQDEQGSKVSDFFDQSSFLHNEM 2182


>gi|31581524 cordon-bleu homolog [Homo sapiens]
          Length = 1261

 Score = 28.5 bits (62), Expect = 6.6
 Identities = 20/60 (33%), Positives = 27/60 (45%), Gaps = 16/60 (26%)

Query: 16  DLEWYEKSEETHASQIELLETSSTQEPLNASEAFCPRDCM--------VPVVFPGPVSQE 67
           DLE  E S ET        +TSS    ++ +   CP+D M        +PV F G VS +
Sbjct: 499 DLEEMEDSYET--------DTSSLTSSIHGASNHCPQDAMIPHGDTDAIPVTFIGEVSDD 550


>gi|63053515 keratin associated protein 10-3 [Homo sapiens]
          Length = 221

 Score = 28.5 bits (62), Expect = 6.6
 Identities = 13/46 (28%), Positives = 18/46 (39%)

Query: 30 QIELLETSSTQEPLNASEAFCPRDCMVPVVFPGPVSQEGCCQFTCE 75
          Q++    S  + P  A+    P  C+  V  P       CCQ  CE
Sbjct: 18 QVDACPESCCEPPCCATSCCAPAPCLTLVCTPVSCVSSPCCQAACE 63


>gi|148612853 ATP-binding cassette, sub-family F (GCN20), member 3
           [Homo sapiens]
          Length = 709

 Score = 28.5 bits (62), Expect = 6.6
 Identities = 14/58 (24%), Positives = 32/58 (55%), Gaps = 1/58 (1%)

Query: 106 EEMLKKKPRATTEVSSRKCQQA-LAELESVLSHLEDFFARTLVPRVLILLGGNALSPK 162
           E++L+++   T ++++ + + +  AEL  + + LE+  A     R  ++L G   +PK
Sbjct: 262 EDLLRRERELTAQIAAGRAEGSEAAELAEIYAKLEEIEADKAPARASVILAGLGFTPK 319


>gi|158508542 kelch-like 33 [Homo sapiens]
          Length = 453

 Score = 28.1 bits (61), Expect = 8.6
 Identities = 16/49 (32%), Positives = 19/49 (38%)

Query: 222 GEDWFRPKLNYRVPSRGHKLTVTLSCGRPSIRTTAWEDYIWFQAPVTFK 270
           G D  RP +  R PSR         CG   +RT  W       AP  F+
Sbjct: 135 GGDGLRPDMALRQPSRAVWWARAFRCGVGLVRTVEWGQLPALPAPGRFR 183


>gi|166197668 CD5 molecule [Homo sapiens]
          Length = 495

 Score = 28.1 bits (61), Expect = 8.6
 Identities = 11/33 (33%), Positives = 16/33 (48%)

Query: 218 HRNCGEDWFRPKLNYRVPSRGHKLTVTLSCGRP 250
           H  C + W R    +  PS+  K+   L+CG P
Sbjct: 57  HMVCSQSWGRSSKQWEDPSQASKVCQRLNCGVP 89


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.133    0.408 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,094,165
Number of Sequences: 37866
Number of extensions: 501927
Number of successful extensions: 1359
Number of sequences better than 10.0: 17
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 1345
Number of HSP's gapped (non-prelim): 22
length of query: 274
length of database: 18,247,518
effective HSP length: 101
effective length of query: 173
effective length of database: 14,423,052
effective search space: 2495187996
effective search space used: 2495187996
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.