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Search of human proteins with 7661888
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7661888 Josephin domain containing 1 [Homo sapiens]
(202 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7661888 Josephin domain containing 1 [Homo sapiens] 425 e-119
gi|19923879 Josephin domain containing 2 [Homo sapiens] 200 6e-52
gi|13518019 ataxin 3 isoform 1 [Homo sapiens] 49 3e-06
gi|209862748 ataxin 3-like [Homo sapiens] 47 1e-05
gi|189163493 ataxin 3 isoform 3 [Homo sapiens] 46 2e-05
gi|13518013 ataxin 3 isoform 2 [Homo sapiens] 34 0.074
gi|189163495 ataxin 3 isoform 4 [Homo sapiens] 33 0.22
gi|14149997 neuroblastoma breakpoint family, member 3 [Homo sapi... 30 1.4
gi|145587088 hypothetical protein LOC165186 [Homo sapiens] 30 1.8
gi|71834872 tumor differentially expressed 2-like [Homo sapiens] 29 2.4
gi|224589132 hypothetical protein LOC100132406 [Homo sapiens] 29 3.1
gi|55956923 5-hydroxytryptamine (serotonin) receptor 1A [Homo sa... 29 3.1
gi|239754192 PREDICTED: hypothetical protein [Homo sapiens] 28 4.1
gi|239748720 PREDICTED: hypothetical protein XP_002346780 [Homo ... 28 4.1
gi|239742755 PREDICTED: hypothetical protein XP_002342628 [Homo ... 28 4.1
gi|83415174 hypothetical protein LOC400818 [Homo sapiens] 28 5.3
gi|92110019 hypothetical protein LOC55672 [Homo sapiens] 28 5.3
gi|8923708 FAD-dependent oxidoreductase domain containing 1 [Hom... 28 6.9
gi|239741309 PREDICTED: hypothetical protein XP_002344485 [Homo ... 27 9.0
gi|114158664 hypothetical protein LOC343505 [Homo sapiens] 27 9.0
>gi|7661888 Josephin domain containing 1 [Homo sapiens]
Length = 202
Score = 425 bits (1093), Expect = e-119
Identities = 202/202 (100%), Positives = 202/202 (100%)
Query: 1 MSCVPWKGDKAKSESLELPQAAPPQIYHEKQRRELCALHALNNVFQDSNAFTRDTLQEIF 60
MSCVPWKGDKAKSESLELPQAAPPQIYHEKQRRELCALHALNNVFQDSNAFTRDTLQEIF
Sbjct: 1 MSCVPWKGDKAKSESLELPQAAPPQIYHEKQRRELCALHALNNVFQDSNAFTRDTLQEIF 60
Query: 61 QRLSPNTMVTPHKKSMLGNGNYDVNVIMAALQTKGYEAVWWDKRRDVGVIALTNVMGFIM 120
QRLSPNTMVTPHKKSMLGNGNYDVNVIMAALQTKGYEAVWWDKRRDVGVIALTNVMGFIM
Sbjct: 61 QRLSPNTMVTPHKKSMLGNGNYDVNVIMAALQTKGYEAVWWDKRRDVGVIALTNVMGFIM 120
Query: 121 NLPSSLCWGPLKLPLKRQHWICVREVGGAYYNLDSKLKMPEWIGGESELRKFLKHHLRGK 180
NLPSSLCWGPLKLPLKRQHWICVREVGGAYYNLDSKLKMPEWIGGESELRKFLKHHLRGK
Sbjct: 121 NLPSSLCWGPLKLPLKRQHWICVREVGGAYYNLDSKLKMPEWIGGESELRKFLKHHLRGK 180
Query: 181 NCELLLVVPEEVEAHQSWRTDV 202
NCELLLVVPEEVEAHQSWRTDV
Sbjct: 181 NCELLLVVPEEVEAHQSWRTDV 202
>gi|19923879 Josephin domain containing 2 [Homo sapiens]
Length = 188
Score = 200 bits (509), Expect = 6e-52
Identities = 101/183 (55%), Positives = 131/183 (71%), Gaps = 3/183 (1%)
Query: 20 QAAPPQIYHEKQRRELCALHALNNVFQDSNAFTRDTLQEIFQRLSPNTMVTPHKKSMLGN 79
Q +PP +YHE+QR ELCA+HALNNV Q F+++ EI +RL+P++ + PH+ S+LG
Sbjct: 8 QPSPPTVYHERQRLELCAVHALNNVLQQQ-LFSQEAADEICKRLAPDSRLNPHR-SLLGT 65
Query: 80 GNYDVNVIMAALQTKGYEAVWWDKRRDVGVIALTNVMGFIMNLPSSLCWGPLKLPLKRQH 139
GNYDVNVIMAALQ G AVWWD+RR + +AL V+G I+NLPS + G L LPL+R+H
Sbjct: 66 GNYDVNVIMAALQGLGLAAVWWDRRRPLSQLALPQVLGLILNLPSPVSLGLLSLPLRRRH 125
Query: 140 WICVREVGGAYYNLDSKLKMPEWIGGESELRKFLKHHLRGKNCELLLVVPEEVEAHQSW- 198
W+ +R+V G YYNLDSKL+ PE +G E +R FL L CE+LLVV +EVE SW
Sbjct: 126 WVALRQVDGVYYNLDSKLRAPEALGDEDGVRAFLAAALAQGLCEVLLVVTKEVEEKGSWL 185
Query: 199 RTD 201
RTD
Sbjct: 186 RTD 188
>gi|13518019 ataxin 3 isoform 1 [Homo sapiens]
Length = 361
Score = 48.9 bits (115), Expect = 3e-06
Identities = 43/155 (27%), Positives = 64/155 (41%), Gaps = 32/155 (20%)
Query: 26 IYHEKQRRELCALHALNNVFQDSNAFTRDTLQEIFQRLSP----------------NTMV 69
I+HEKQ LCA H LNN+ Q F+ L I +L T +
Sbjct: 4 IFHEKQEGSLCAQHCLNNLLQ-GEYFSPVELSSIAHQLDEEERMRMAEGGVTSEDYRTFL 62
Query: 70 TPHKKSMLGNGNYDVNVIMAALQTKGYEAVWWDKRRDVGV-IALTNVMGFIMNLPSSLCW 128
+M +G + + VI AL+ G E + ++ + I N FI N
Sbjct: 63 QQPSGNMDDSGFFSIQVISNALKVWGLELILFNSPEYQRLRIDPINERSFICNY------ 116
Query: 129 GPLKLPLKRQHWICVREVGGAYYNLDSKLKMPEWI 163
++HW VR++G ++NL+S L PE I
Sbjct: 117 --------KEHWFTVRKLGKQWFNLNSLLTGPELI 143
>gi|209862748 ataxin 3-like [Homo sapiens]
Length = 355
Score = 46.6 bits (109), Expect = 1e-05
Identities = 42/156 (26%), Positives = 66/156 (42%), Gaps = 34/156 (21%)
Query: 26 IYHEKQRRELCALHALNNVFQDSNAFTRDTLQEIFQRLSPN----------------TMV 69
I+HEKQ LCA H LNN+ Q F+ L I +L +
Sbjct: 4 IFHEKQEGFLCAQHCLNNLLQ-GEYFSPVELASIAHQLDEEERMRMAEGGVTSEEYLAFL 62
Query: 70 TPHKKSMLGNGNYDVNVIMAALQTKGYEAVWWD--KRRDVGVIALTNVMGFIMNLPSSLC 127
++M G + + VI AL+ G E + ++ + + +G+ + N FI N
Sbjct: 63 QQPSENMDDTGFFSIQVISNALKFWGLEIIHFNNPEYQKLGIDPI-NERSFICNY----- 116
Query: 128 WGPLKLPLKRQHWICVREVGGAYYNLDSKLKMPEWI 163
+QHW +R+ G ++NL+S L PE I
Sbjct: 117 ---------KQHWFTIRKFGKHWFNLNSLLAGPELI 143
>gi|189163493 ataxin 3 isoform 3 [Homo sapiens]
Length = 346
Score = 45.8 bits (107), Expect = 2e-05
Identities = 40/140 (28%), Positives = 60/140 (42%), Gaps = 17/140 (12%)
Query: 26 IYHEKQRRELCALHALNNVFQDSNAFTRDTLQEIFQRLSPNTMVTPHKKSMLGNG-NYDV 84
I+HEKQ LCA H LNN+ Q F+ L I +L + + + +
Sbjct: 4 IFHEKQEGSLCAQHCLNNLLQ-GEYFSPVELSSIAHQLDEEERMRMAEGGVTSEDYRTFL 62
Query: 85 NVIMAALQTKGYEAVWWDKRRDVGV-IALTNVMGFIMNLPSSLCWGPLKLPLKRQHWICV 143
VI AL+ G E + ++ + I N FI N ++HW V
Sbjct: 63 QVISNALKVWGLELILFNSPEYQRLRIDPINERSFICNY--------------KEHWFTV 108
Query: 144 REVGGAYYNLDSKLKMPEWI 163
R++G ++NL+S L PE I
Sbjct: 109 RKLGKQWFNLNSLLTGPELI 128
>gi|13518013 ataxin 3 isoform 2 [Homo sapiens]
Length = 306
Score = 34.3 bits (77), Expect = 0.074
Identities = 28/97 (28%), Positives = 43/97 (44%), Gaps = 19/97 (19%)
Query: 72 HKKSMLGN----GNYDVNVIMAALQTKGYEAVWWDKRRDVGV-IALTNVMGFIMNLPSSL 126
H+K GN G + + VI AL+ G E + ++ + I N FI N
Sbjct: 6 HEKQPSGNMDDSGFFSIQVISNALKVWGLELILFNSPEYQRLRIDPINERSFICNY---- 61
Query: 127 CWGPLKLPLKRQHWICVREVGGAYYNLDSKLKMPEWI 163
++HW VR++G ++NL+S L PE I
Sbjct: 62 ----------KEHWFTVRKLGKQWFNLNSLLTGPELI 88
>gi|189163495 ataxin 3 isoform 4 [Homo sapiens]
Length = 295
Score = 32.7 bits (73), Expect = 0.22
Identities = 13/21 (61%), Positives = 15/21 (71%)
Query: 26 IYHEKQRRELCALHALNNVFQ 46
I+HEKQ LCA H LNN+ Q
Sbjct: 4 IFHEKQEGSLCAQHCLNNLLQ 24
>gi|14149997 neuroblastoma breakpoint family, member 3 [Homo
sapiens]
Length = 633
Score = 30.0 bits (66), Expect = 1.4
Identities = 12/32 (37%), Positives = 20/32 (62%)
Query: 1 MSCVPWKGDKAKSESLELPQAAPPQIYHEKQR 32
+S PW G+KA+ LE+ + + PQ+ KQ+
Sbjct: 59 VSAGPWSGEKAEMNILEINKKSRPQLAENKQQ 90
>gi|145587088 hypothetical protein LOC165186 [Homo sapiens]
Length = 1019
Score = 29.6 bits (65), Expect = 1.8
Identities = 20/60 (33%), Positives = 31/60 (51%), Gaps = 2/60 (3%)
Query: 38 LHALNNVFQDSNAFTRDTLQEIFQRLSPNTMVTPHKKSMLGNGNYDVNVIMAALQTKGYE 97
+H L + QDSN TR +++ L NT K L + YD+ +MAA++ +G E
Sbjct: 656 VHNLVRLAQDSNQDTRFYGRKMVNILMANTKFDAFLKQSLPS--YDLQKVMAAIKQQGIE 713
>gi|71834872 tumor differentially expressed 2-like [Homo sapiens]
Length = 455
Score = 29.3 bits (64), Expect = 2.4
Identities = 16/46 (34%), Positives = 21/46 (45%), Gaps = 7/46 (15%)
Query: 65 PNTMVTPHKKSMLGNGNYDVNVIMAALQTKGYEAVWWDKRRDVGVI 110
P PH + LGN ++A +GYE WWD VG+I
Sbjct: 290 PEQKCNPHLPTQLGN-----ETVVAG--PEGYETQWWDAPSIVGLI 328
>gi|224589132 hypothetical protein LOC100132406 [Homo sapiens]
Length = 3628
Score = 28.9 bits (63), Expect = 3.1
Identities = 15/45 (33%), Positives = 24/45 (53%), Gaps = 4/45 (8%)
Query: 1 MSCVPWKGDKAKSESLELPQAAPPQIYHEKQR----RELCALHAL 41
+S PW +KA+ LE+ + PQ+ +KQ+ +E C L L
Sbjct: 3 VSAGPWSSEKAEMNILEINETLRPQLAEKKQQFRNLKEKCFLTQL 47
>gi|55956923 5-hydroxytryptamine (serotonin) receptor 1A [Homo
sapiens]
Length = 422
Score = 28.9 bits (63), Expect = 3.1
Identities = 15/55 (27%), Positives = 27/55 (49%), Gaps = 7/55 (12%)
Query: 104 RRDVGVIALTNVMGFIMNLPSSLCW-------GPLKLPLKRQHWICVREVGGAYY 151
RR +I+LT ++GF++++P L W P + + H + GA+Y
Sbjct: 151 RRAAALISLTWLIGFLISIPPMLGWRTPEDRSDPDACTISKDHGYTIYSTFGAFY 205
>gi|239754192 PREDICTED: hypothetical protein [Homo sapiens]
Length = 211
Score = 28.5 bits (62), Expect = 4.1
Identities = 10/24 (41%), Positives = 17/24 (70%)
Query: 139 HWICVREVGGAYYNLDSKLKMPEW 162
H+ICVR++GG+ +L K+ + W
Sbjct: 92 HYICVRDLGGSPPSLSPKMTVTAW 115
>gi|239748720 PREDICTED: hypothetical protein XP_002346780 [Homo
sapiens]
Length = 211
Score = 28.5 bits (62), Expect = 4.1
Identities = 10/24 (41%), Positives = 17/24 (70%)
Query: 139 HWICVREVGGAYYNLDSKLKMPEW 162
H+ICVR++GG+ +L K+ + W
Sbjct: 92 HYICVRDLGGSPPSLSPKMTVTAW 115
>gi|239742755 PREDICTED: hypothetical protein XP_002342628 [Homo
sapiens]
Length = 211
Score = 28.5 bits (62), Expect = 4.1
Identities = 10/24 (41%), Positives = 17/24 (70%)
Query: 139 HWICVREVGGAYYNLDSKLKMPEW 162
H+ICVR++GG+ +L K+ + W
Sbjct: 92 HYICVRDLGGSPPSLSPKMTVTAW 115
>gi|83415174 hypothetical protein LOC400818 [Homo sapiens]
Length = 942
Score = 28.1 bits (61), Expect = 5.3
Identities = 15/45 (33%), Positives = 23/45 (51%), Gaps = 4/45 (8%)
Query: 1 MSCVPWKGDKAKSESLELPQAAPPQIYHEKQR----RELCALHAL 41
+S PW +KA+ LE+ + PQ+ KQ+ +E C L L
Sbjct: 3 VSAGPWSSEKAEMNILEINEKLRPQLAENKQQFGNLKERCFLTQL 47
>gi|92110019 hypothetical protein LOC55672 [Homo sapiens]
Length = 1214
Score = 28.1 bits (61), Expect = 5.3
Identities = 11/32 (34%), Positives = 19/32 (59%)
Query: 1 MSCVPWKGDKAKSESLELPQAAPPQIYHEKQR 32
+S PW +KA++ LE+ + PQ+ KQ+
Sbjct: 3 VSAGPWSSEKAETNILEINEKLRPQLAENKQQ 34
>gi|8923708 FAD-dependent oxidoreductase domain containing 1 [Homo
sapiens]
Length = 486
Score = 27.7 bits (60), Expect = 6.9
Identities = 11/25 (44%), Positives = 18/25 (72%)
Query: 161 EWIGGESELRKFLKHHLRGKNCELL 185
+W G SE++K +K L G++C+LL
Sbjct: 29 DWDGKVSEIKKKIKSILPGRSCDLL 53
>gi|239741309 PREDICTED: hypothetical protein XP_002344485 [Homo
sapiens]
Length = 4621
Score = 27.3 bits (59), Expect = 9.0
Identities = 11/32 (34%), Positives = 18/32 (56%)
Query: 1 MSCVPWKGDKAKSESLELPQAAPPQIYHEKQR 32
+S PW +KA+ LE+ + PQ+ KQ+
Sbjct: 3 VSAGPWSSEKAEMNILEINEKLRPQLAENKQQ 34
>gi|114158664 hypothetical protein LOC343505 [Homo sapiens]
Length = 421
Score = 27.3 bits (59), Expect = 9.0
Identities = 11/32 (34%), Positives = 18/32 (56%)
Query: 1 MSCVPWKGDKAKSESLELPQAAPPQIYHEKQR 32
+S PW +KA+ LE+ + PQ+ KQ+
Sbjct: 23 VSAGPWSSEKAEMNILEINEKLRPQLAENKQQ 54
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.135 0.431
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,309,531
Number of Sequences: 37866
Number of extensions: 350660
Number of successful extensions: 778
Number of sequences better than 10.0: 20
Number of HSP's better than 10.0 without gapping: 17
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 751
Number of HSP's gapped (non-prelim): 25
length of query: 202
length of database: 18,247,518
effective HSP length: 97
effective length of query: 105
effective length of database: 14,574,516
effective search space: 1530324180
effective search space used: 1530324180
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.