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Search of human proteins with 7661862
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7661862 protein phosphatase 1F [Homo sapiens]
(454 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7661862 protein phosphatase 1F [Homo sapiens] 905 0.0
gi|30089948 protein phosphatase 1E [Homo sapiens] 368 e-102
gi|122937199 protein phosphatase 1B-like [Homo sapiens] 132 6e-31
gi|13540531 integrin-linked kinase-associated protein phosphatas... 125 8e-29
gi|63003905 protein phosphatase 1 (formerly 2C)-like [Homo sapiens] 112 9e-25
gi|167466276 protein phosphatase 1K (PP2C domain containing) [Ho... 103 3e-22
gi|75813620 protein phosphatase 1B isoform 5 [Homo sapiens] 99 1e-20
gi|29558022 protein phosphatase 1B isoform 2 [Homo sapiens] 99 1e-20
gi|4505995 protein phosphatase 1B isoform 1 [Homo sapiens] 99 1e-20
gi|75813618 protein phosphatase 1B isoform 4 [Homo sapiens] 98 1e-20
gi|10337595 protein phosphatase 1A isoform 1 [Homo sapiens] 96 5e-20
gi|29557855 protein phosphatase 1A isoform 2 [Homo sapiens] 96 5e-20
gi|193211600 protein phosphatase 1A isoform 3 [Homo sapiens] 96 5e-20
gi|4505999 protein phosphatase 1G [Homo sapiens] 92 1e-18
gi|29826282 protein phosphatase 1G [Homo sapiens] 92 1e-18
gi|4505997 protein phosphatase 1D [Homo sapiens] 78 1e-14
gi|149944715 protein phosphatase 1H (PP2C domain containing) [Ho... 57 5e-08
gi|65506328 protein phosphatase 1J (PP2C domain containing) [Hom... 52 1e-06
gi|37221175 PH domain and leucine rich repeat protein phosphatas... 52 1e-06
gi|65301141 PH domain and leucine rich repeat protein phosphatas... 51 2e-06
gi|171460932 protein phosphatase 1M isoform a [Homo sapiens] 50 3e-06
gi|41349497 pyruvate dehydrogenase phosphatase isoenzyme 2 [Homo... 47 5e-05
gi|45439339 pyruvate dehyrogenase phosphatase catalytic subunit ... 45 2e-04
gi|239985428 pyruvate dehyrogenase phosphatase catalytic subunit... 45 2e-04
gi|239985426 pyruvate dehyrogenase phosphatase catalytic subunit... 45 2e-04
gi|239985422 pyruvate dehyrogenase phosphatase catalytic subunit... 45 2e-04
gi|239985420 pyruvate dehyrogenase phosphatase catalytic subunit... 45 2e-04
gi|171460934 protein phosphatase 1M isoform b [Homo sapiens] 39 0.010
gi|119709834 castor homolog 1, zinc finger isoform a [Homo sapiens] 38 0.022
gi|21735492 protein phosphatase 1, regulatory (inhibitor) subuni... 37 0.048
>gi|7661862 protein phosphatase 1F [Homo sapiens]
Length = 454
Score = 905 bits (2338), Expect = 0.0
Identities = 454/454 (100%), Positives = 454/454 (100%)
Query: 1 MSSGAPQKSSPMASGAEETPGFLDTLLQDFPALLNPEDPLPWKAPGTVLSQEEVEGELAE 60
MSSGAPQKSSPMASGAEETPGFLDTLLQDFPALLNPEDPLPWKAPGTVLSQEEVEGELAE
Sbjct: 1 MSSGAPQKSSPMASGAEETPGFLDTLLQDFPALLNPEDPLPWKAPGTVLSQEEVEGELAE 60
Query: 61 LAMGFLGSRKAPPPLAAALAHEAVSQLLQTDLSEFRKLPREEEEEEEDDDEEEKAPVTLL 120
LAMGFLGSRKAPPPLAAALAHEAVSQLLQTDLSEFRKLPREEEEEEEDDDEEEKAPVTLL
Sbjct: 61 LAMGFLGSRKAPPPLAAALAHEAVSQLLQTDLSEFRKLPREEEEEEEDDDEEEKAPVTLL 120
Query: 121 DAQSLAQSFFNRLWEVAGQWQKQVPLAARASQRQWLVSIHAIRNTRRKMEDRHVSLPSFN 180
DAQSLAQSFFNRLWEVAGQWQKQVPLAARASQRQWLVSIHAIRNTRRKMEDRHVSLPSFN
Sbjct: 121 DAQSLAQSFFNRLWEVAGQWQKQVPLAARASQRQWLVSIHAIRNTRRKMEDRHVSLPSFN 180
Query: 181 QLFGLSDPVNRAYFAVFDGHGGVDAARYAAVHVHTNAARQPELPTDPEGALREAFRRTDQ 240
QLFGLSDPVNRAYFAVFDGHGGVDAARYAAVHVHTNAARQPELPTDPEGALREAFRRTDQ
Sbjct: 181 QLFGLSDPVNRAYFAVFDGHGGVDAARYAAVHVHTNAARQPELPTDPEGALREAFRRTDQ 240
Query: 241 MFLRKAKRERLQSGTTGVCALIAGATLHVAWLGDSQVILVQQGQVVKLMEPHRPERQDEK 300
MFLRKAKRERLQSGTTGVCALIAGATLHVAWLGDSQVILVQQGQVVKLMEPHRPERQDEK
Sbjct: 241 MFLRKAKRERLQSGTTGVCALIAGATLHVAWLGDSQVILVQQGQVVKLMEPHRPERQDEK 300
Query: 301 ARIEALGGFVSHMDCWRVNGTLAVSRAIGDVFQKPYVSGEADAASRALTGSEDYLLLACD 360
ARIEALGGFVSHMDCWRVNGTLAVSRAIGDVFQKPYVSGEADAASRALTGSEDYLLLACD
Sbjct: 301 ARIEALGGFVSHMDCWRVNGTLAVSRAIGDVFQKPYVSGEADAASRALTGSEDYLLLACD 360
Query: 361 GFFDVVPHQEVVGLVQSHLTRQQGSGLRVAEELVAAARERGSHDNITVMVVFLRDPQELL 420
GFFDVVPHQEVVGLVQSHLTRQQGSGLRVAEELVAAARERGSHDNITVMVVFLRDPQELL
Sbjct: 361 GFFDVVPHQEVVGLVQSHLTRQQGSGLRVAEELVAAARERGSHDNITVMVVFLRDPQELL 420
Query: 421 EGGNQGEGDPQAEGRRQDLPSSLPEPETQAPPRS 454
EGGNQGEGDPQAEGRRQDLPSSLPEPETQAPPRS
Sbjct: 421 EGGNQGEGDPQAEGRRQDLPSSLPEPETQAPPRS 454
>gi|30089948 protein phosphatase 1E [Homo sapiens]
Length = 755
Score = 368 bits (945), Expect = e-102
Identities = 200/385 (51%), Positives = 253/385 (65%), Gaps = 12/385 (3%)
Query: 31 PALLNPEDPLPWKAPGTVLSQEEVEGELAELAMGFLGSRKAPPPLAAALAHEAVSQLLQT 90
P L P PLP + +++EEVEGE +L + L P LAAALA ++LQ+
Sbjct: 118 PPQLPPLPPLP-RPLSERITREEVEGESLDLCLQQLYKYNCPSFLAAALARATSDEVLQS 176
Query: 91 DLSEFRKLPREEEEEEEDDDEEEKAPVTLLDAQSLAQSFFNRLWEVAGQWQKQVPLAARA 150
DLS +P+E + E + ++ LA+S F++L E+ W K PL R
Sbjct: 177 DLSA-HYIPKETDGTEGTVE---------IETVKLARSVFSKLHEICCSWVKDFPLRRRP 226
Query: 151 SQRQWLVSIHAIRNTRRKMEDRHVSLPSFNQLFGLSDPVNRAYFAVFDGHGGVDAARYAA 210
Q + SIHAI+N RRKMED+HV +P FN LF L D +AYFAVFDGHGGVDAA YA+
Sbjct: 227 -QLYYETSIHAIKNMRRKMEDKHVCIPDFNMLFNLEDQEEQAYFAVFDGHGGVDAAIYAS 285
Query: 211 VHVHTNAARQPELPTDPEGALREAFRRTDQMFLRKAKRERLQSGTTGVCALIAGATLHVA 270
+H+H N RQ P DP AL AFR TD+ F++KA RE L+ GTTGV I G LHVA
Sbjct: 286 IHLHVNLVRQEMFPHDPAEALCRAFRVTDERFVQKAARESLRCGTTGVVTFIRGNMLHVA 345
Query: 271 WLGDSQVILVQQGQVVKLMEPHRPERQDEKARIEALGGFVSHMDCWRVNGTLAVSRAIGD 330
W+GDSQV+LV++GQ V+LM+PH+P+R+DEK RIEALGG V WRVNG+L+VSRAIGD
Sbjct: 346 WVGDSQVMLVRKGQAVELMKPHKPDREDEKQRIEALGGCVVWFGAWRVNGSLSVSRAIGD 405
Query: 331 VFQKPYVSGEADAASRALTGSEDYLLLACDGFFDVVPHQEVVGLVQSHLTRQQGSGLRVA 390
KPY+ G+AD+AS L G+EDYL+LACDGF+D V E V +V HL G VA
Sbjct: 406 AEHKPYICGDADSASTVLDGTEDYLILACDGFYDTVNPDEAVKVVSDHLKENNGDSSMVA 465
Query: 391 EELVAAARERGSHDNITVMVVFLRD 415
+LVA+AR+ GS DNITV+VVFLRD
Sbjct: 466 HKLVASARDAGSSDNITVIVVFLRD 490
>gi|122937199 protein phosphatase 1B-like [Homo sapiens]
Length = 430
Score = 132 bits (332), Expect = 6e-31
Identities = 115/332 (34%), Positives = 154/332 (46%), Gaps = 41/332 (12%)
Query: 94 EFRKLPREEEEEEEDDDEEEKAPVTLLDAQSLAQSFFNRLWEVAGQWQKQVPLAARASQR 153
E K REEEEEEE + P +LL A AQ P +
Sbjct: 20 EREKEGREEEEEEEAGRRAPEGPRSLLTAPRRAQR----------------PHGGAEASG 63
Query: 154 QWLVSIHAIRNTRRKMEDRHVSLPSFNQLFGLSDPVNRAYFAVFDGHGGVDAARYAAVHV 213
A + R +MED H + S L P A FAV DGHGG AAR+ A H+
Sbjct: 64 GLRFGASAAQGWRARMEDAHCTWLSLPGL-----PPGWALFAVLDGHGGARAARFGARHL 118
Query: 214 HTNAARQ--PELPTDPEG---ALREAFRRTDQMFLRKAKRERLQSGTTGVCALIAGATLH 268
+ ++ PE P++PEG ALR AF D+ LR G T V L++ L+
Sbjct: 119 PGHVLQELGPE-PSEPEGVREALRRAFLSADER-LRSLWPRVETGGCTAVVLLVSPRFLY 176
Query: 269 VAWLGDSQVILVQQGQVVKLMEPHRPERQDEKARIEALGGFVSHMDCWRVNGTLAVSRAI 328
+A GDS+ +L + G V E HRP R E+ RI A GG + RV G+LAVSRA+
Sbjct: 177 LAHCGDSRAVLSRAGAVAFSTEDHRPLRPRERERIHAAGGTIRRR---RVEGSLAVSRAL 233
Query: 329 GDVFQK---------PYVSGEADAASRALTGSEDYLLLACDGFFDVVPHQEVVGLVQSHL 379
GD K VS E + A+ A ++++LLA DG +D V + GLV S L
Sbjct: 234 GDFTYKEAPGRPPELQLVSAEPEVAALARQAEDEFMLLASDGVWDTVSGAALAGLVASRL 293
Query: 380 TRQQGSGLRVAEELVAAARERGSHDNITVMVV 411
L A +L+ +GS DN+T ++V
Sbjct: 294 RLGLAPELLCA-QLLDTCLCKGSLDNMTCILV 324
>gi|13540531 integrin-linked kinase-associated protein phosphatase
2C [Homo sapiens]
Length = 392
Score = 125 bits (314), Expect = 8e-29
Identities = 95/277 (34%), Positives = 143/277 (51%), Gaps = 31/277 (11%)
Query: 163 RNTRRKMEDRHVSLPSFNQ-LFGLSDPVNR-AYFAVFDGHGGVDAARYAAVHVHTNAARQ 220
+ R +M+D HV L + S + R +YFAVFDGHGG+ A+++AA ++H N R+
Sbjct: 115 KGEREEMQDAHVILNDITEECRPPSSLITRVSYFAVFDGHGGIRASKFAAQNLHQNLIRK 174
Query: 221 ------PELPTDPEGALREAFRRTDQMFLRKAKRER--LQSGTTGVCALIAGATLHVAWL 272
+ + L + F+ TD+ FL++A ++ + G+T C L L++A L
Sbjct: 175 FPKGDVISVEKTVKRCLLDTFKHTDEEFLKQASSQKPAWKDGSTATCVLAVDNILYIANL 234
Query: 273 GDSQVILV------QQGQVVKLMEPHRPERQDEKARIEALGGFVSHMDCWRVNGTLAVSR 326
GDS+ IL Q+ + L + H P + +E+ RI+ GG V RV G L VSR
Sbjct: 235 GDSRAILCRYNEESQKHAALSLSKEHNPTQYEERMRIQKAGGNVRD---GRVLGVLEVSR 291
Query: 327 AIGD-VFQKPYVSGEADAASRALTGSEDYLLLACDGFFDVVPHQEVVGLVQSHL------ 379
+IGD +++ V+ D LT ++ ++LLACDG F V +E V + S L
Sbjct: 292 SIGDGQYKRCGVTSVPDIRRCQLTPNDRFILLACDGLFKVFTPEEAVNFILSCLEDEKIQ 351
Query: 380 TRQQGSGLRVAEE-----LVAAARERGSHDNITVMVV 411
TR+ S E L A +RGS DN+TVMVV
Sbjct: 352 TREGKSAADARYEAACNRLANKAVQRGSADNVTVMVV 388
>gi|63003905 protein phosphatase 1 (formerly 2C)-like [Homo sapiens]
Length = 360
Score = 112 bits (279), Expect = 9e-25
Identities = 87/278 (31%), Positives = 138/278 (49%), Gaps = 24/278 (8%)
Query: 157 VSIHAIRNTRRKMEDRHVSLPSFNQLFGLSDPVNRAYFAVFDGHGGVDAARYAAVHVHTN 216
V++++I+ R MEDR F L L++ + + F +FDGHGG AA Y +
Sbjct: 93 VAVYSIQGRRDHMEDR------FEVLTDLANKTHPSIFGIFDGHGGETAAEYVKSRL-PE 145
Query: 217 AARQ--PELPTDPEGA-------LREAFRRTDQMFLRKAKRERLQSGTTGVCALIAGATL 267
A +Q + D E + L + D+ L K ++GTT + AL++ L
Sbjct: 146 ALKQHLQDYEKDKENSVLSYQTILEQQILSIDREMLEKLTVSYDEAGTTCLIALLSDKDL 205
Query: 268 HVAWLGDSQVILVQQ-GQVVKLMEPHRPERQDEKARIEALGGFVSHMDCWRVNGTLAVSR 326
VA +GDS+ +L + G + L H+P + E+ RI+ GGF+S WRV G LA+SR
Sbjct: 206 TVANVGDSRGVLCDKDGNAIPLSHDHKPYQLKERKRIKRAGGFISFNGSWRVQGILAMSR 265
Query: 327 AIGDVFQK--PYVSGEADAASRALTGSE-DYLLLACDGFFDVVPHQEVVGLVQSHLTRQQ 383
++GD K V + D + L + ++++LA DG +D ++E V ++ L
Sbjct: 266 SLGDYPLKNLNVVIPDPDILTFDLDKLQPEFMILASDGLWDAFSNEEAVRFIKERLDEPH 325
Query: 384 GSGLRVAEELVAAARERGSHDNITVMVVFLRDPQELLE 421
A+ +V + RG DNITVMVV R+ + E
Sbjct: 326 FG----AKSIVLQSFYRGCPDNITVMVVKFRNSSKTEE 359
>gi|167466276 protein phosphatase 1K (PP2C domain containing) [Homo
sapiens]
Length = 372
Score = 103 bits (257), Expect = 3e-22
Identities = 95/258 (36%), Positives = 130/258 (50%), Gaps = 29/258 (11%)
Query: 166 RRKMEDRHVSLPSFNQLFGLSDPVNRAYFAVFDGHGGVDAARYAAVHVHTNAARQPELPT 225
R++ EDR F QL +D V YFAV+DGHGG AA + H H LP
Sbjct: 104 RKENEDRF----DFAQL---TDEV--LYFAVYDGHGGPAAADFC--HTHMEKCIMDLLPK 152
Query: 226 DP--EGALREAFRRTDQMFLRKAKRER----LQSGTTGVCALIA-GATLHVAWLGDSQVI 278
+ E L AF D+ F A+ L SGTT AL+ G L VA +GDS+ I
Sbjct: 153 EKNLETLLTLAFLEIDKAFSSHARLSADATLLTSGTTATVALLRDGIELVVASVGDSRAI 212
Query: 279 LVQQGQVVKLMEPHRPERQDEKARIEALGGFVSHMDCWR--VNGTLAVSRAIGDVFQKPY 336
L ++G+ +KL H PER+DEK RI+ GGFV+ + VNG LA++R+IGD+ K
Sbjct: 213 LCRKGKPMKLTIDHTPERKDEKERIKKCGGFVAWNSLGQPHVNGRLAMTRSIGDLDLKTS 272
Query: 337 -VSGEADAASRALTGSED-YLLLACDGFFDVVPHQEVVGLV-QSHLTRQQGSGLRVAEEL 393
V E + L ++D +L+L DG +V QE+ V Q H + A +
Sbjct: 273 GVIAEPETKRIKLHHADDSFLVLTTDGINFMVNSQEICDFVNQCHDPNE------AAHAV 326
Query: 394 VAAARERGSHDNITVMVV 411
A + G+ DN T +VV
Sbjct: 327 TEQAIQYGTEDNSTAVVV 344
>gi|75813620 protein phosphatase 1B isoform 5 [Homo sapiens]
Length = 380
Score = 98.6 bits (244), Expect = 1e-20
Identities = 82/308 (26%), Positives = 143/308 (46%), Gaps = 37/308 (12%)
Query: 159 IHAIRNTRRKMEDRHVSLPSFNQLFGLSDPVNRAYFAVFDGHGGVDAARYAAVHVHTNAA 218
+ +++ R +MED H ++ GL D ++FAV+DGH G A Y + H+ +
Sbjct: 26 LSSMQGWRVEMEDAHTAVVGIPH--GLED---WSFFAVYDGHAGSRVANYCSTHLLEHIT 80
Query: 219 RQPELPT-------------DPEGALREAFRRTDQMFLRKAKRERL---QSGTTGVCALI 262
+ + + +R F + D+ ++R R +SG+T V +I
Sbjct: 81 TNEDFRAAGKSGSALELSVENVKNGIRTGFLKIDE-YMRNFSDLRNGMDRSGSTAVGVMI 139
Query: 263 AGATLHVAWLGDSQVILVQQGQVVKLMEPHRPERQDEKARIEALGGFVSHMDCWRVNGTL 322
+ ++ GDS+ +L + GQV + H+P EK RI+ GG V RVNG+L
Sbjct: 140 SPKHIYFINCGDSRAVLYRNGQVCFSTQDHKPCNPREKERIQNAGGSVM---IQRVNGSL 196
Query: 323 AVSRAIGDVFQK---------PYVSGEADAASRALTGSEDYLLLACDGFFDVVPHQEVVG 373
AVSRA+GD K VS E + +++++LACDG +DV+ ++E+
Sbjct: 197 AVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEILRAEEDEFIILACDGIWDVMSNEELCE 256
Query: 374 LVQSHLTRQQGSGLRVAEELVAAARERGSHDNITVMVVFLRDPQELLEGG--NQGEGDPQ 431
V+S L V +V +GS DN+++++V + ++ + E D
Sbjct: 257 YVKSRLEVSDDLE-NVCNWVVDTCLHKGSRDNMSIVLVCFSNAPKVSDEAVKKDSELDKH 315
Query: 432 AEGRRQDL 439
E R +++
Sbjct: 316 LESRVEEI 323
>gi|29558022 protein phosphatase 1B isoform 2 [Homo sapiens]
Length = 387
Score = 98.6 bits (244), Expect = 1e-20
Identities = 82/308 (26%), Positives = 143/308 (46%), Gaps = 37/308 (12%)
Query: 159 IHAIRNTRRKMEDRHVSLPSFNQLFGLSDPVNRAYFAVFDGHGGVDAARYAAVHVHTNAA 218
+ +++ R +MED H ++ GL D ++FAV+DGH G A Y + H+ +
Sbjct: 26 LSSMQGWRVEMEDAHTAVVGIPH--GLED---WSFFAVYDGHAGSRVANYCSTHLLEHIT 80
Query: 219 RQPELPT-------------DPEGALREAFRRTDQMFLRKAKRERL---QSGTTGVCALI 262
+ + + +R F + D+ ++R R +SG+T V +I
Sbjct: 81 TNEDFRAAGKSGSALELSVENVKNGIRTGFLKIDE-YMRNFSDLRNGMDRSGSTAVGVMI 139
Query: 263 AGATLHVAWLGDSQVILVQQGQVVKLMEPHRPERQDEKARIEALGGFVSHMDCWRVNGTL 322
+ ++ GDS+ +L + GQV + H+P EK RI+ GG V RVNG+L
Sbjct: 140 SPKHIYFINCGDSRAVLYRNGQVCFSTQDHKPCNPREKERIQNAGGSVM---IQRVNGSL 196
Query: 323 AVSRAIGDVFQK---------PYVSGEADAASRALTGSEDYLLLACDGFFDVVPHQEVVG 373
AVSRA+GD K VS E + +++++LACDG +DV+ ++E+
Sbjct: 197 AVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEILRAEEDEFIILACDGIWDVMSNEELCE 256
Query: 374 LVQSHLTRQQGSGLRVAEELVAAARERGSHDNITVMVVFLRDPQELLEGG--NQGEGDPQ 431
V+S L V +V +GS DN+++++V + ++ + E D
Sbjct: 257 YVKSRLEVSDDLE-NVCNWVVDTCLHKGSRDNMSIVLVCFSNAPKVSDEAVKKDSELDKH 315
Query: 432 AEGRRQDL 439
E R +++
Sbjct: 316 LESRVEEI 323
>gi|4505995 protein phosphatase 1B isoform 1 [Homo sapiens]
Length = 479
Score = 98.6 bits (244), Expect = 1e-20
Identities = 82/308 (26%), Positives = 143/308 (46%), Gaps = 37/308 (12%)
Query: 159 IHAIRNTRRKMEDRHVSLPSFNQLFGLSDPVNRAYFAVFDGHGGVDAARYAAVHVHTNAA 218
+ +++ R +MED H ++ GL D ++FAV+DGH G A Y + H+ +
Sbjct: 26 LSSMQGWRVEMEDAHTAVVGIPH--GLED---WSFFAVYDGHAGSRVANYCSTHLLEHIT 80
Query: 219 RQPELPT-------------DPEGALREAFRRTDQMFLRKAKRERL---QSGTTGVCALI 262
+ + + +R F + D+ ++R R +SG+T V +I
Sbjct: 81 TNEDFRAAGKSGSALELSVENVKNGIRTGFLKIDE-YMRNFSDLRNGMDRSGSTAVGVMI 139
Query: 263 AGATLHVAWLGDSQVILVQQGQVVKLMEPHRPERQDEKARIEALGGFVSHMDCWRVNGTL 322
+ ++ GDS+ +L + GQV + H+P EK RI+ GG V RVNG+L
Sbjct: 140 SPKHIYFINCGDSRAVLYRNGQVCFSTQDHKPCNPREKERIQNAGGSVM---IQRVNGSL 196
Query: 323 AVSRAIGDVFQK---------PYVSGEADAASRALTGSEDYLLLACDGFFDVVPHQEVVG 373
AVSRA+GD K VS E + +++++LACDG +DV+ ++E+
Sbjct: 197 AVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEILRAEEDEFIILACDGIWDVMSNEELCE 256
Query: 374 LVQSHLTRQQGSGLRVAEELVAAARERGSHDNITVMVVFLRDPQELLEGG--NQGEGDPQ 431
V+S L V +V +GS DN+++++V + ++ + E D
Sbjct: 257 YVKSRLEVSDDLE-NVCNWVVDTCLHKGSRDNMSIVLVCFSNAPKVSDEAVKKDSELDKH 315
Query: 432 AEGRRQDL 439
E R +++
Sbjct: 316 LESRVEEI 323
>gi|75813618 protein phosphatase 1B isoform 4 [Homo sapiens]
Length = 327
Score = 98.2 bits (243), Expect = 1e-20
Identities = 78/278 (28%), Positives = 132/278 (47%), Gaps = 35/278 (12%)
Query: 159 IHAIRNTRRKMEDRHVSLPSFNQLFGLSDPVNRAYFAVFDGHGGVDAARYAAVHVHTNAA 218
+ +++ R +MED H ++ GL D ++FAV+DGH G A Y + H+ +
Sbjct: 26 LSSMQGWRVEMEDAHTAVVGIPH--GLED---WSFFAVYDGHAGSRVANYCSTHLLEHIT 80
Query: 219 RQPELPT-------------DPEGALREAFRRTDQMFLRKAKRERL---QSGTTGVCALI 262
+ + + +R F + D+ ++R R +SG+T V +I
Sbjct: 81 TNEDFRAAGKSGSALELSVENVKNGIRTGFLKIDE-YMRNFSDLRNGMDRSGSTAVGVMI 139
Query: 263 AGATLHVAWLGDSQVILVQQGQVVKLMEPHRPERQDEKARIEALGGFVSHMDCWRVNGTL 322
+ ++ GDS+ +L + GQV + H+P EK RI+ GG V RVNG+L
Sbjct: 140 SPKHIYFINCGDSRAVLYRNGQVCFSTQDHKPCNPREKERIQNAGGSVM---IQRVNGSL 196
Query: 323 AVSRAIGDVFQK---------PYVSGEADAASRALTGSEDYLLLACDGFFDVVPHQEVVG 373
AVSRA+GD K VS E + +++++LACDG +DV+ ++E+
Sbjct: 197 AVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEILRAEEDEFIILACDGIWDVMSNEELCE 256
Query: 374 LVQSHLTRQQGSGLRVAEELVAAARERGSHDNITVMVV 411
V+S L V +V +GS DN+++++V
Sbjct: 257 YVKSRLEVSDDLE-NVCNWVVDTCLHKGSRDNMSIVLV 293
>gi|10337595 protein phosphatase 1A isoform 1 [Homo sapiens]
Length = 382
Score = 96.3 bits (238), Expect = 5e-20
Identities = 83/277 (29%), Positives = 134/277 (48%), Gaps = 37/277 (13%)
Query: 159 IHAIRNTRRKMEDRH---VSLPSFNQLFGLSDPVNRAYFAVFDGHGGVDAARYAAVHV-- 213
+ +++ R +MED H + LPS GL + ++FAV+DGH G A+Y H+
Sbjct: 26 LSSMQGWRVEMEDAHTAVIGLPS-----GLE---SWSFFAVYDGHAGSQVAKYCCEHLLD 77
Query: 214 -------HTNAARQPELPTDPEGALREAFRRTDQMF--LRKAKRERLQSGTTGVCALIAG 264
+A P + G +R F D+ + + K +SG+T V LI+
Sbjct: 78 HITNNQDFKGSAGAPSVENVKNG-IRTGFLEIDEHMRVMSEKKHGADRSGSTAVGVLISP 136
Query: 265 ATLHVAWLGDSQVILVQQGQVVKLMEPHRPERQDEKARIEALGGFVSHMDCWRVNGTLAV 324
+ GDS+ +L + +V + H+P EK RI+ GG V RVNG+LAV
Sbjct: 137 QHTYFINCGDSRGLLCRNRKVHFFTQDHKPSNPLEKERIQNAGGSVM---IQRVNGSLAV 193
Query: 325 SRAIGDVFQK---------PYVSGEADAASRALTGSED-YLLLACDGFFDVVPHQEVVGL 374
SRA+GD K VS E + + +D +++LACDG +DV+ ++E+
Sbjct: 194 SRALGDFDYKCVHGKGPTEQLVSPEPEVHDIERSEEDDQFIILACDGIWDVMGNEELCDF 253
Query: 375 VQSHLTRQQGSGLRVAEELVAAARERGSHDNITVMVV 411
V+S L +V E+V +GS DN++V+++
Sbjct: 254 VRSRLEVTDDLE-KVCNEVVDTCLYKGSRDNMSVILI 289
>gi|29557855 protein phosphatase 1A isoform 2 [Homo sapiens]
Length = 324
Score = 96.3 bits (238), Expect = 5e-20
Identities = 83/277 (29%), Positives = 134/277 (48%), Gaps = 37/277 (13%)
Query: 159 IHAIRNTRRKMEDRH---VSLPSFNQLFGLSDPVNRAYFAVFDGHGGVDAARYAAVHV-- 213
+ +++ R +MED H + LPS GL + ++FAV+DGH G A+Y H+
Sbjct: 26 LSSMQGWRVEMEDAHTAVIGLPS-----GLE---SWSFFAVYDGHAGSQVAKYCCEHLLD 77
Query: 214 -------HTNAARQPELPTDPEGALREAFRRTDQMF--LRKAKRERLQSGTTGVCALIAG 264
+A P + G +R F D+ + + K +SG+T V LI+
Sbjct: 78 HITNNQDFKGSAGAPSVENVKNG-IRTGFLEIDEHMRVMSEKKHGADRSGSTAVGVLISP 136
Query: 265 ATLHVAWLGDSQVILVQQGQVVKLMEPHRPERQDEKARIEALGGFVSHMDCWRVNGTLAV 324
+ GDS+ +L + +V + H+P EK RI+ GG V RVNG+LAV
Sbjct: 137 QHTYFINCGDSRGLLCRNRKVHFFTQDHKPSNPLEKERIQNAGGSVM---IQRVNGSLAV 193
Query: 325 SRAIGDVFQK---------PYVSGEADAASRALTGSED-YLLLACDGFFDVVPHQEVVGL 374
SRA+GD K VS E + + +D +++LACDG +DV+ ++E+
Sbjct: 194 SRALGDFDYKCVHGKGPTEQLVSPEPEVHDIERSEEDDQFIILACDGIWDVMGNEELCDF 253
Query: 375 VQSHLTRQQGSGLRVAEELVAAARERGSHDNITVMVV 411
V+S L +V E+V +GS DN++V+++
Sbjct: 254 VRSRLEVTDDLE-KVCNEVVDTCLYKGSRDNMSVILI 289
>gi|193211600 protein phosphatase 1A isoform 3 [Homo sapiens]
Length = 455
Score = 96.3 bits (238), Expect = 5e-20
Identities = 83/277 (29%), Positives = 134/277 (48%), Gaps = 37/277 (13%)
Query: 159 IHAIRNTRRKMEDRH---VSLPSFNQLFGLSDPVNRAYFAVFDGHGGVDAARYAAVHV-- 213
+ +++ R +MED H + LPS GL + ++FAV+DGH G A+Y H+
Sbjct: 99 LSSMQGWRVEMEDAHTAVIGLPS-----GLE---SWSFFAVYDGHAGSQVAKYCCEHLLD 150
Query: 214 -------HTNAARQPELPTDPEGALREAFRRTDQMF--LRKAKRERLQSGTTGVCALIAG 264
+A P + G +R F D+ + + K +SG+T V LI+
Sbjct: 151 HITNNQDFKGSAGAPSVENVKNG-IRTGFLEIDEHMRVMSEKKHGADRSGSTAVGVLISP 209
Query: 265 ATLHVAWLGDSQVILVQQGQVVKLMEPHRPERQDEKARIEALGGFVSHMDCWRVNGTLAV 324
+ GDS+ +L + +V + H+P EK RI+ GG V RVNG+LAV
Sbjct: 210 QHTYFINCGDSRGLLCRNRKVHFFTQDHKPSNPLEKERIQNAGGSVM---IQRVNGSLAV 266
Query: 325 SRAIGDVFQK---------PYVSGEADAASRALTGSED-YLLLACDGFFDVVPHQEVVGL 374
SRA+GD K VS E + + +D +++LACDG +DV+ ++E+
Sbjct: 267 SRALGDFDYKCVHGKGPTEQLVSPEPEVHDIERSEEDDQFIILACDGIWDVMGNEELCDF 326
Query: 375 VQSHLTRQQGSGLRVAEELVAAARERGSHDNITVMVV 411
V+S L +V E+V +GS DN++V+++
Sbjct: 327 VRSRLEVTDDLE-KVCNEVVDTCLYKGSRDNMSVILI 362
>gi|4505999 protein phosphatase 1G [Homo sapiens]
Length = 546
Score = 91.7 bits (226), Expect = 1e-18
Identities = 60/152 (39%), Positives = 89/152 (58%), Gaps = 12/152 (7%)
Query: 253 SGTTGVCALIAGATLHVAWLGDSQVILVQQGQVVKLMEPHRPERQDEKARIEALGGFVSH 312
SGTT V ALI G L VA GDS+ ++ + G+ + + H+PE + E ARI+ GG V+
Sbjct: 327 SGTTAVVALIRGKQLIVANAGDSRCVVSEAGKALDMSYDHKPEDEVELARIKNAGGKVT- 385
Query: 313 MDCWRVNGTLAVSRAIGDVFQK---------PYVSGEADAASRALTGSEDYLLLACDGFF 363
MD RVNG L +SRAIGD F K +S D LT +++++ACDG +
Sbjct: 386 MD-GRVNGGLNLSRAIGDHFYKRNKNLPPEEQMISALPDIKVLTLTDDHEFMVIACDGIW 444
Query: 364 DVVPHQEVVGLVQSHLTRQQGSG-LRVAEELV 394
+V+ QEVV +QS ++++ +G LR+ +V
Sbjct: 445 NVMSSQEVVDFIQSKISQRDENGELRLLSSIV 476
Score = 34.7 bits (78), Expect = 0.18
Identities = 18/53 (33%), Positives = 27/53 (50%), Gaps = 8/53 (15%)
Query: 161 AIRNTRRKMEDRHVSLPSFNQLFGLSDPVNRAYFAVFDGHGGVDAARYAAVHV 213
A++ R MED H +P + A F+V+DGHGG + A Y A ++
Sbjct: 31 AMQGWRVSMEDAHNCIPELDS--------ETAMFSVYDGHGGEEVALYCAKYL 75
>gi|29826282 protein phosphatase 1G [Homo sapiens]
Length = 546
Score = 91.7 bits (226), Expect = 1e-18
Identities = 60/152 (39%), Positives = 89/152 (58%), Gaps = 12/152 (7%)
Query: 253 SGTTGVCALIAGATLHVAWLGDSQVILVQQGQVVKLMEPHRPERQDEKARIEALGGFVSH 312
SGTT V ALI G L VA GDS+ ++ + G+ + + H+PE + E ARI+ GG V+
Sbjct: 327 SGTTAVVALIRGKQLIVANAGDSRCVVSEAGKALDMSYDHKPEDEVELARIKNAGGKVT- 385
Query: 313 MDCWRVNGTLAVSRAIGDVFQK---------PYVSGEADAASRALTGSEDYLLLACDGFF 363
MD RVNG L +SRAIGD F K +S D LT +++++ACDG +
Sbjct: 386 MD-GRVNGGLNLSRAIGDHFYKRNKNLPPEEQMISALPDIKVLTLTDDHEFMVIACDGIW 444
Query: 364 DVVPHQEVVGLVQSHLTRQQGSG-LRVAEELV 394
+V+ QEVV +QS ++++ +G LR+ +V
Sbjct: 445 NVMSSQEVVDFIQSKISQRDENGELRLLSSIV 476
Score = 34.7 bits (78), Expect = 0.18
Identities = 18/53 (33%), Positives = 27/53 (50%), Gaps = 8/53 (15%)
Query: 161 AIRNTRRKMEDRHVSLPSFNQLFGLSDPVNRAYFAVFDGHGGVDAARYAAVHV 213
A++ R MED H +P + A F+V+DGHGG + A Y A ++
Sbjct: 31 AMQGWRVSMEDAHNCIPELDS--------ETAMFSVYDGHGGEEVALYCAKYL 75
>gi|4505997 protein phosphatase 1D [Homo sapiens]
Length = 605
Score = 78.2 bits (191), Expect = 1e-14
Identities = 67/232 (28%), Positives = 107/232 (46%), Gaps = 47/232 (20%)
Query: 192 AYFAVFDGHGGVDAARYAAVHVHTNAARQPEL----PTDPEGALREAFRRTD-QMFLRKA 246
A+FAV DGHGG +AA++A H+ +Q P A+R+ F M+ + A
Sbjct: 99 AFFAVCDGHGGREAAQFAREHLWGFIKKQKGFTSSEPAKVCAAIRKGFLACHLAMWKKLA 158
Query: 247 KRERLQ------SGTTGVCALIAGATLHVAWLGDSQVILVQQG-------QVVKLMEPHR 293
+ + SGTT +I G ++VA +GDS V+L Q + V++ + H+
Sbjct: 159 EWPKTMTGLPSTSGTTASVVIIRGMKMYVAHVGDSGVVLGIQDDPKDDFVRAVEVTQDHK 218
Query: 294 PERQDEKARIEALGGFVSHMD-----CWR-----VNGT------------LAVSRAIGDV 331
PE E+ RIE LGG V + W+ NG LAV+RA+GD+
Sbjct: 219 PELPKERERIEGLGGSVMNKSGVNRVVWKRPRLTHNGPVRRSTVIDQIPFLAVARALGDL 278
Query: 332 FQKPYVSGEADAASRALTG-------SEDYLLLACDGFFDVVPHQEVVGLVQ 376
+ + SGE + T Y++L DG ++++P Q+ + + Q
Sbjct: 279 WSYDFFSGEFVVSPEPDTSVHTLDPQKHKYIILGSDGLWNMIPPQDAISMCQ 330
>gi|149944715 protein phosphatase 1H (PP2C domain containing) [Homo
sapiens]
Length = 514
Score = 56.6 bits (135), Expect = 5e-08
Identities = 59/263 (22%), Positives = 101/263 (38%), Gaps = 80/263 (30%)
Query: 229 GALREAFRRTDQMFLRKAKRERLQSGTTGVCALIAGATLHVAWLGDSQVILVQQGQVVKL 288
GAL AF+ D R+ + G T + + L+VA GDS+ I+++ G+++ +
Sbjct: 243 GALESAFKEMDLQIERERSSYNISGGCTALIVICLLGKLYVANAGDSRAIIIRNGEIIPM 302
Query: 289 MEPHRPERQDEKARIEA------LGGFVSHMDC----------------------W---- 316
PE + ++ + A LG +H++ W
Sbjct: 303 SSEFTPETERQRLQYLAFMQPHLLGNEFTHLEFPRRVQRKELGKKMLYRDFNMTGWAYKT 362
Query: 317 ------------------RVNGTLAVSRAIGD---------VFQKPYVSGEADAASRALT 349
RV T+ V+R +GD ++ KP++S + L+
Sbjct: 363 IEDEDLKFPLIYGEGKKARVMATIGVTRGLGDHDLKVHDSNIYIKPFLSSAPEVRIYDLS 422
Query: 350 ----GSEDYLLLACDGFFDVVPHQEVVGLVQSHLTRQQGSG----LRVAEELVAAAR--- 398
GS+D L+LA DG +DV+ ++EV + L A++LV AR
Sbjct: 423 KYDHGSDDVLILATDGLWDVLSNEEVAEAITQFLPNCDPDDPHRYTLAAQDLVMRARGVL 482
Query: 399 ----------ERGSHDNITVMVV 411
GS D+I+V V+
Sbjct: 483 KDRGWRISNDRLGSGDDISVYVI 505
>gi|65506328 protein phosphatase 1J (PP2C domain containing) [Homo
sapiens]
Length = 505
Score = 52.0 bits (123), Expect = 1e-06
Identities = 74/349 (21%), Positives = 125/349 (35%), Gaps = 125/349 (35%)
Query: 193 YFAVFDGHGGVDAARYAAVHVHTNAARQPE---------------LPTDPE--------- 228
Y+ +FDGH G AA A+ +H + Q + LPT P
Sbjct: 153 YWGLFDGHAGGGAAEMASRLLHRHIREQLKDLVEILQDPSPPPLCLPTTPGTPDSSDPSH 212
Query: 229 ---------------------GALREAFRRTDQMFLRKAKRERLQSGTTGVCALIAGATL 267
GA+ AF+ D+ R+ + +++ G + + +
Sbjct: 213 LLGPQSCWSSQKEVSHESLVVGAVENAFQLMDEQMARERRGHQVEGGCCALVVIYLLGKV 272
Query: 268 HVAWLGDSQVILVQQGQVVKLMEPHRPERQDEKARI------EALGGFVSHMDC------ 315
+VA GDS+ I+V+ G+++ + PE + ++ ++ E LG +H++
Sbjct: 273 YVANAGDSRAIIVRNGEIIPMSREFTPETERQRLQLLGFLKPELLGSEFTHLEFPRRVLP 332
Query: 316 ----------------W----------------------RVNGTLAVSRAIGD------- 330
W RV T+ V+R +GD
Sbjct: 333 KELGQRMLYRDQNMTGWAYKKIELEDLRFPLVCGEGKKARVMATIGVTRGLGDHSLKVCS 392
Query: 331 --VFQKPYVSGEADAASRALTGSE----DYLLLACDGFFDVVPHQEVVGLVQSHLTRQQG 384
+ KP++S + LT E D L+L DG +DV EV V L+ +
Sbjct: 393 STLPIKPFLSCFPEVRVYDLTQYEHCPDDVLVLGTDGLWDVTTDCEVAATVDRVLSAYEP 452
Query: 385 SG----LRVAEELVAAAR-------------ERGSHDNITVMVVFLRDP 416
+ +A+ LV AR + GS D+I+V V+ L P
Sbjct: 453 NDHSRYTALAQALVLGARGTPRDRGWRLPNNKLGSGDDISVFVIPLGGP 501
>gi|37221175 PH domain and leucine rich repeat protein phosphatase
[Homo sapiens]
Length = 1205
Score = 51.6 bits (122), Expect = 1e-06
Identities = 40/148 (27%), Positives = 68/148 (45%), Gaps = 7/148 (4%)
Query: 266 TLHVAWLGDSQVILVQQGQVVKLMEPHRPERQDEKARIEALGGFVSHMDCWRVNGTLAVS 325
TL A +G Q +L + G+ + L + ++E RI+ ++ + +VNG +
Sbjct: 770 TLTSANVGKCQTVLCRNGKPLPLSRSYIMSCEEELKRIKQHKAIIT--EDGKVNGVTEST 827
Query: 326 RAIGDVFQKPYVSGEADAASRALTGSEDYLLLACDGFFDVVPHQEVVGLVQSHLTRQQGS 385
R +G F P V S LT +++ +L G +D + +E V V R
Sbjct: 828 RILGYTFLHPSVVPRPHVQSVLLTPQDEFFILGSKGLWDSLSVEEAVEAV-----RNVPD 882
Query: 386 GLRVAEELVAAARERGSHDNITVMVVFL 413
L A++L A+ G HD+I+ +VV L
Sbjct: 883 ALAAAKKLCTLAQSYGCHDSISAVVVQL 910
>gi|65301141 PH domain and leucine rich repeat protein
phosphatase-like [Homo sapiens]
Length = 1323
Score = 50.8 bits (120), Expect = 2e-06
Identities = 40/154 (25%), Positives = 74/154 (48%), Gaps = 8/154 (5%)
Query: 266 TLHVAWLGDSQVILVQQGQVVKLMEPHRPERQDEKA-RIEALGGFVSHMDCWRVNGTLAV 324
+L VA +G Q +L + G+ V L + E+ E+A R++ ++ + +VNG
Sbjct: 892 SLTVANVGTCQAVLCRGGKPVPLSKVFSLEQDPEEAQRVKDQKAIITEDN--KVNGVTCC 949
Query: 325 SRAIGDVFQKPYVSGEADAASRALTGSEDYLLLACDGFFDVVPHQEVVGLVQSHLTRQQG 384
+R +G + P++ + +S LT ++ L+L ++ + + E V V R
Sbjct: 950 TRMLGCTYLYPWILPKPHISSTPLTIQDELLILGNKALWEHLSYTEAVNAV-----RHVQ 1004
Query: 385 SGLRVAEELVAAARERGSHDNITVMVVFLRDPQE 418
L A++L A+ G DN+ MVV+L +E
Sbjct: 1005 DPLAAAKKLCTLAQSYGCQDNVGAMVVYLNIGEE 1038
>gi|171460932 protein phosphatase 1M isoform a [Homo sapiens]
Length = 298
Score = 50.4 bits (119), Expect = 3e-06
Identities = 63/260 (24%), Positives = 105/260 (40%), Gaps = 79/260 (30%)
Query: 229 GALREAFRRTDQMFLRKAKRERLQSGTTGVCALIAGATLHVAWLGDSQVILVQQGQVVKL 288
GAL AF+ D++ R+ + G T + A+ L++A GDS+ ILV++ ++ L
Sbjct: 29 GALESAFQECDEVIGRELEASGQMGGCTALVAVSLQGKLYMANAGDSRAILVRRDEIRPL 88
Query: 289 MEPHRPERQDEKARIEAL---------GGFV---------------------SHMDCW-- 316
PE E+ RI+ L G F HM W
Sbjct: 89 SFEFTPE--TERQRIQQLAFVYPELLAGEFTRLEFPRRLKGDDLGQKVLFRDHHMSGWSY 146
Query: 317 --------------------RVNGTLAVSRAIGD---------VFQKPYVSGEADA---- 343
R+ GTLAVSR +GD + KP++
Sbjct: 147 KRVEKSDLKYPLIHGQGRQARLLGTLAVSRGLGDHQLRVLDTNIQLKPFLLSVPQVTVLD 206
Query: 344 ASRALTGSEDYLLLACDGFFDVVPHQEVVGLVQSHLTRQQGSGLR---VAEELVAAAR-- 398
+ +D +++A DG +DV+ +++V LV+S L Q R +A+ L+ + +
Sbjct: 207 VDQLELQEDDVVVMATDGLWDVLSNEQVAWLVRSFLPGNQEDPHRFSKLAQMLIHSTQGK 266
Query: 399 -----ERG--SHDNITVMVV 411
E G S+D+++V V+
Sbjct: 267 EDSLTEEGQVSYDDVSVFVI 286
>gi|41349497 pyruvate dehydrogenase phosphatase isoenzyme 2 [Homo
sapiens]
Length = 529
Score = 46.6 bits (109), Expect = 5e-05
Identities = 51/203 (25%), Positives = 80/203 (39%), Gaps = 53/203 (26%)
Query: 253 SGTTGVCALIAGATLHVAWLGDSQVIL-VQQGQ----VVKLMEPHRPERQDEKARI---- 303
SG T A + G LHVA GD + IL VQ+ + L H Q E +R+
Sbjct: 265 SGATACMAHVDGIHLHVANAGDCRAILGVQEDNGMWSCLPLTRDHNAWNQAELSRLKREH 324
Query: 304 -EALGGFVSHMDCWRVNGTLAVSRAIGDV------------------------------- 331
E+ + D R+ G L RA GDV
Sbjct: 325 PESEDRTIIMED--RLLGVLIPCRAFGDVQLKWSKELQRSILERGFNTEALNIYQFTPPH 382
Query: 332 -FQKPYVSGEADAASRALTGSEDYLLLACDGFFDVVPHQEVVGLVQSHLTR--------- 381
+ PY++ E + L + +L+LA DG +D++ +++VV LV HL
Sbjct: 383 YYTPPYLTAEPEVTYHRLRPQDKFLVLASDGLWDMLSNEDVVRLVVGHLAEADWHKTDLA 442
Query: 382 QQGSGLRVAEELVAAARERGSHD 404
Q+ + L + + L+ + G H+
Sbjct: 443 QRPANLGLMQSLLLQRKASGLHE 465
>gi|45439339 pyruvate dehyrogenase phosphatase catalytic subunit 1
isoform 3 precursor [Homo sapiens]
Length = 537
Score = 44.7 bits (104), Expect = 2e-04
Identities = 54/210 (25%), Positives = 78/210 (37%), Gaps = 57/210 (27%)
Query: 226 DPEGALREAFRRTDQ------------MFLRKAKRERLQSGTTGVCALIAGATLHVAWLG 273
D + AL AF+R D FL SG T A + G LHVA G
Sbjct: 231 DVKEALINAFKRLDNDISLEAQVGDPNSFLNYLVLRVAFSGATACVAHVDGVDLHVANTG 290
Query: 274 DSQVILVQQGQ-----VVKLMEPHRPERQDEKARIE-----ALGGFVSHMDCWRVNGTLA 323
DS+ +L Q + V L H + + E R++ + V D R+ G L
Sbjct: 291 DSRAMLGVQEEDGSWSAVTLSNDHNAQNERELERLKLEHPKSEAKSVVKQD--RLLGLLM 348
Query: 324 VSRAIGDVFQK---------------------------------PYVSGEADAASRALTG 350
RA GDV K PY++ E + L
Sbjct: 349 PFRAFGDVKFKWSIDLQKRVIESGPDQLNDNEYTKFIPPNYHTPPYLTAEPEVTYHRLRP 408
Query: 351 SEDYLLLACDGFFDVVPHQEVVGLVQSHLT 380
+ +L+LA DG ++ + Q+VV +V +LT
Sbjct: 409 QDKFLVLATDGLWETMHRQDVVRIVGEYLT 438
>gi|239985428 pyruvate dehyrogenase phosphatase catalytic subunit 1
isoform 3 precursor [Homo sapiens]
Length = 537
Score = 44.7 bits (104), Expect = 2e-04
Identities = 54/210 (25%), Positives = 78/210 (37%), Gaps = 57/210 (27%)
Query: 226 DPEGALREAFRRTDQ------------MFLRKAKRERLQSGTTGVCALIAGATLHVAWLG 273
D + AL AF+R D FL SG T A + G LHVA G
Sbjct: 231 DVKEALINAFKRLDNDISLEAQVGDPNSFLNYLVLRVAFSGATACVAHVDGVDLHVANTG 290
Query: 274 DSQVILVQQGQ-----VVKLMEPHRPERQDEKARIE-----ALGGFVSHMDCWRVNGTLA 323
DS+ +L Q + V L H + + E R++ + V D R+ G L
Sbjct: 291 DSRAMLGVQEEDGSWSAVTLSNDHNAQNERELERLKLEHPKSEAKSVVKQD--RLLGLLM 348
Query: 324 VSRAIGDVFQK---------------------------------PYVSGEADAASRALTG 350
RA GDV K PY++ E + L
Sbjct: 349 PFRAFGDVKFKWSIDLQKRVIESGPDQLNDNEYTKFIPPNYHTPPYLTAEPEVTYHRLRP 408
Query: 351 SEDYLLLACDGFFDVVPHQEVVGLVQSHLT 380
+ +L+LA DG ++ + Q+VV +V +LT
Sbjct: 409 QDKFLVLATDGLWETMHRQDVVRIVGEYLT 438
>gi|239985426 pyruvate dehyrogenase phosphatase catalytic subunit 1
isoform 2 [Homo sapiens]
Length = 562
Score = 44.7 bits (104), Expect = 2e-04
Identities = 54/210 (25%), Positives = 78/210 (37%), Gaps = 57/210 (27%)
Query: 226 DPEGALREAFRRTDQ------------MFLRKAKRERLQSGTTGVCALIAGATLHVAWLG 273
D + AL AF+R D FL SG T A + G LHVA G
Sbjct: 256 DVKEALINAFKRLDNDISLEAQVGDPNSFLNYLVLRVAFSGATACVAHVDGVDLHVANTG 315
Query: 274 DSQVILVQQGQ-----VVKLMEPHRPERQDEKARIE-----ALGGFVSHMDCWRVNGTLA 323
DS+ +L Q + V L H + + E R++ + V D R+ G L
Sbjct: 316 DSRAMLGVQEEDGSWSAVTLSNDHNAQNERELERLKLEHPKSEAKSVVKQD--RLLGLLM 373
Query: 324 VSRAIGDVFQK---------------------------------PYVSGEADAASRALTG 350
RA GDV K PY++ E + L
Sbjct: 374 PFRAFGDVKFKWSIDLQKRVIESGPDQLNDNEYTKFIPPNYHTPPYLTAEPEVTYHRLRP 433
Query: 351 SEDYLLLACDGFFDVVPHQEVVGLVQSHLT 380
+ +L+LA DG ++ + Q+VV +V +LT
Sbjct: 434 QDKFLVLATDGLWETMHRQDVVRIVGEYLT 463
>gi|239985422 pyruvate dehyrogenase phosphatase catalytic subunit 1
isoform 2 [Homo sapiens]
Length = 562
Score = 44.7 bits (104), Expect = 2e-04
Identities = 54/210 (25%), Positives = 78/210 (37%), Gaps = 57/210 (27%)
Query: 226 DPEGALREAFRRTDQ------------MFLRKAKRERLQSGTTGVCALIAGATLHVAWLG 273
D + AL AF+R D FL SG T A + G LHVA G
Sbjct: 256 DVKEALINAFKRLDNDISLEAQVGDPNSFLNYLVLRVAFSGATACVAHVDGVDLHVANTG 315
Query: 274 DSQVILVQQGQ-----VVKLMEPHRPERQDEKARIE-----ALGGFVSHMDCWRVNGTLA 323
DS+ +L Q + V L H + + E R++ + V D R+ G L
Sbjct: 316 DSRAMLGVQEEDGSWSAVTLSNDHNAQNERELERLKLEHPKSEAKSVVKQD--RLLGLLM 373
Query: 324 VSRAIGDVFQK---------------------------------PYVSGEADAASRALTG 350
RA GDV K PY++ E + L
Sbjct: 374 PFRAFGDVKFKWSIDLQKRVIESGPDQLNDNEYTKFIPPNYHTPPYLTAEPEVTYHRLRP 433
Query: 351 SEDYLLLACDGFFDVVPHQEVVGLVQSHLT 380
+ +L+LA DG ++ + Q+VV +V +LT
Sbjct: 434 QDKFLVLATDGLWETMHRQDVVRIVGEYLT 463
>gi|239985420 pyruvate dehyrogenase phosphatase catalytic subunit 1
isoform 1 [Homo sapiens]
Length = 596
Score = 44.7 bits (104), Expect = 2e-04
Identities = 54/210 (25%), Positives = 78/210 (37%), Gaps = 57/210 (27%)
Query: 226 DPEGALREAFRRTDQ------------MFLRKAKRERLQSGTTGVCALIAGATLHVAWLG 273
D + AL AF+R D FL SG T A + G LHVA G
Sbjct: 290 DVKEALINAFKRLDNDISLEAQVGDPNSFLNYLVLRVAFSGATACVAHVDGVDLHVANTG 349
Query: 274 DSQVILVQQGQ-----VVKLMEPHRPERQDEKARIE-----ALGGFVSHMDCWRVNGTLA 323
DS+ +L Q + V L H + + E R++ + V D R+ G L
Sbjct: 350 DSRAMLGVQEEDGSWSAVTLSNDHNAQNERELERLKLEHPKSEAKSVVKQD--RLLGLLM 407
Query: 324 VSRAIGDVFQK---------------------------------PYVSGEADAASRALTG 350
RA GDV K PY++ E + L
Sbjct: 408 PFRAFGDVKFKWSIDLQKRVIESGPDQLNDNEYTKFIPPNYHTPPYLTAEPEVTYHRLRP 467
Query: 351 SEDYLLLACDGFFDVVPHQEVVGLVQSHLT 380
+ +L+LA DG ++ + Q+VV +V +LT
Sbjct: 468 QDKFLVLATDGLWETMHRQDVVRIVGEYLT 497
>gi|171460934 protein phosphatase 1M isoform b [Homo sapiens]
Length = 247
Score = 38.9 bits (89), Expect = 0.010
Identities = 56/235 (23%), Positives = 93/235 (39%), Gaps = 79/235 (33%)
Query: 254 GTTGVCALIAGATLHVAWLGDSQVILVQQGQVVKLMEPHRPERQDEKARIEAL------- 306
G T + A+ L++A GDS+ ILV++ ++ L PE E+ RI+ L
Sbjct: 3 GCTALVAVSLQGKLYMANAGDSRAILVRRDEIRPLSFEFTPET--ERQRIQQLAFVYPEL 60
Query: 307 --GGFVS---------------------HMDCW----------------------RVNGT 321
G F HM W R+ GT
Sbjct: 61 LAGEFTRLEFPRRLKGDDLGQKVLFRDHHMSGWSYKRVEKSDLKYPLIHGQGRQARLLGT 120
Query: 322 LAVSRAIGD---------VFQKPYVSGEADAA----SRALTGSEDYLLLACDGFFDVVPH 368
LAVSR +GD + KP++ + +D +++A DG +DV+ +
Sbjct: 121 LAVSRGLGDHQLRVLDTNIQLKPFLLSVPQVTVLDVDQLELQEDDVVVMATDGLWDVLSN 180
Query: 369 QEVVGLVQSHLTRQQGSGLR---VAEELVAAAR-------ERG--SHDNITVMVV 411
++V LV+S L Q R +A+ L+ + + E G S+D+++V V+
Sbjct: 181 EQVAWLVRSFLPGNQEDPHRFSKLAQMLIHSTQGKEDSLTEEGQVSYDDVSVFVI 235
>gi|119709834 castor homolog 1, zinc finger isoform a [Homo sapiens]
Length = 1759
Score = 37.7 bits (86), Expect = 0.022
Identities = 26/75 (34%), Positives = 37/75 (49%), Gaps = 7/75 (9%)
Query: 45 PGTVLSQEEVEGELAELAMGFLGSRKAP------PPLAAALAHEAVSQLLQTDLSEFRKL 98
PG++L + L LA+G G P P AA A A + Q D E +L
Sbjct: 1626 PGSLLFLQSAAAGLG-LALGDAGDPGPPDAAAPGPREGAAAAAAAAGESSQEDEEEELEL 1684
Query: 99 PREEEEEEEDDDEEE 113
P EE E++ED+D++E
Sbjct: 1685 PEEEAEDDEDEDDDE 1699
>gi|21735492 protein phosphatase 1, regulatory (inhibitor) subunit
1B isoform 1 [Homo sapiens]
Length = 204
Score = 36.6 bits (83), Expect = 0.048
Identities = 17/28 (60%), Positives = 23/28 (82%), Gaps = 2/28 (7%)
Query: 89 QTDLSEFRKL--PREEEEEEEDDDEEEK 114
+ +L E R+L PREE+EEEE+DDEEE+
Sbjct: 105 EDELGELRELGYPREEDEEEEEDDEEEE 132
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.132 0.385
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,022,980
Number of Sequences: 37866
Number of extensions: 926584
Number of successful extensions: 11611
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 106
Number of HSP's successfully gapped in prelim test: 75
Number of HSP's that attempted gapping in prelim test: 9925
Number of HSP's gapped (non-prelim): 1068
length of query: 454
length of database: 18,247,518
effective HSP length: 106
effective length of query: 348
effective length of database: 14,233,722
effective search space: 4953335256
effective search space used: 4953335256
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.