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Search of human proteins with 7661666
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7661666 testin isoform 1 [Homo sapiens]
(421 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7661666 testin isoform 1 [Homo sapiens] 909 0.0
gi|23238188 testin isoform 2 [Homo sapiens] 891 0.0
gi|7657309 LIM and cysteine-rich domains 1 [Homo sapiens] 386 e-107
gi|7710129 LIM domain only 6 [Homo sapiens] 288 5e-78
gi|38524620 prickle-like 2 [Homo sapiens] 255 5e-68
gi|222136684 prickle homolog 1 [Homo sapiens] 252 5e-67
gi|222136682 prickle homolog 1 [Homo sapiens] 252 5e-67
gi|222136680 prickle homolog 1 [Homo sapiens] 252 5e-67
gi|222136678 prickle homolog 1 [Homo sapiens] 252 5e-67
gi|118722347 over-expressed breast tumor protein [Homo sapiens] 142 7e-34
gi|87159836 four and a half LIM domains 2 [Homo sapiens] 100 2e-21
gi|87159834 four and a half LIM domains 2 [Homo sapiens] 100 2e-21
gi|42403575 four and a half LIM domains 2 [Homo sapiens] 100 2e-21
gi|87159832 four and a half LIM domains 2 [Homo sapiens] 100 2e-21
gi|228480213 four and a half LIM domains 1 isoform 2 [Homo sapiens] 94 3e-19
gi|228480211 four and a half LIM domains 1 isoform 1 [Homo sapiens] 94 3e-19
gi|228480207 four and a half LIM domains 1 isoform 2 [Homo sapiens] 94 3e-19
gi|228480209 four and a half LIM domains 1 isoform 3 [Homo sapiens] 94 3e-19
gi|228480205 four and a half LIM domains 1 isoform 5 [Homo sapiens] 94 3e-19
gi|21361122 four and a half LIM domains 1 isoform 2 [Homo sapiens] 94 3e-19
gi|170932518 paxillin isoform 3 [Homo sapiens] 86 6e-17
gi|170932516 paxillin isoform 2 [Homo sapiens] 86 6e-17
gi|170932514 paxillin isoform 1 [Homo sapiens] 86 6e-17
gi|221316659 leupaxin isoform 1 [Homo sapiens] 86 6e-17
gi|4758670 leupaxin isoform 2 [Homo sapiens] 86 6e-17
gi|122056614 LIM domain binding 3 isoform 2 [Homo sapiens] 84 2e-16
gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens] 84 2e-16
gi|54112385 four and a half LIM domains 3 [Homo sapiens] 84 2e-16
gi|30410801 activator of cAMP-responsive element modulator (CREM... 84 2e-16
gi|109638745 transforming growth factor beta 1 induced transcrip... 82 1e-15
>gi|7661666 testin isoform 1 [Homo sapiens]
Length = 421
Score = 909 bits (2348), Expect = 0.0
Identities = 421/421 (100%), Positives = 421/421 (100%)
Query: 1 MDLENKVKKMGLGHEQGFGAPCLKCKEKCEGFELHFWRKICRNCKCGQEEHDVLLSNEED 60
MDLENKVKKMGLGHEQGFGAPCLKCKEKCEGFELHFWRKICRNCKCGQEEHDVLLSNEED
Sbjct: 1 MDLENKVKKMGLGHEQGFGAPCLKCKEKCEGFELHFWRKICRNCKCGQEEHDVLLSNEED 60
Query: 61 RKVGKLFEDTKYTTLIAKLKSDGIPMYKRNVMILTNPVAAKKNVSINTVTYEWAPPVQNQ 120
RKVGKLFEDTKYTTLIAKLKSDGIPMYKRNVMILTNPVAAKKNVSINTVTYEWAPPVQNQ
Sbjct: 61 RKVGKLFEDTKYTTLIAKLKSDGIPMYKRNVMILTNPVAAKKNVSINTVTYEWAPPVQNQ 120
Query: 121 ALARQYMQMLPKEKQPVAGSEGAQYRKKQLAKQLPAHDQDPSKCHELSPREVKEMEQFVK 180
ALARQYMQMLPKEKQPVAGSEGAQYRKKQLAKQLPAHDQDPSKCHELSPREVKEMEQFVK
Sbjct: 121 ALARQYMQMLPKEKQPVAGSEGAQYRKKQLAKQLPAHDQDPSKCHELSPREVKEMEQFVK 180
Query: 181 KYKSEALGVGDVKLPCEMDAQGPKQMNIPGGDRSTPAAVGAMEDKSAEHKRTQYSCYCCK 240
KYKSEALGVGDVKLPCEMDAQGPKQMNIPGGDRSTPAAVGAMEDKSAEHKRTQYSCYCCK
Sbjct: 181 KYKSEALGVGDVKLPCEMDAQGPKQMNIPGGDRSTPAAVGAMEDKSAEHKRTQYSCYCCK 240
Query: 241 LSMKEGDPAIYAERAGYDKLWHPACFVCSTCHELLVDMIYFWKNEKLYCGRHYCDSEKPR 300
LSMKEGDPAIYAERAGYDKLWHPACFVCSTCHELLVDMIYFWKNEKLYCGRHYCDSEKPR
Sbjct: 241 LSMKEGDPAIYAERAGYDKLWHPACFVCSTCHELLVDMIYFWKNEKLYCGRHYCDSEKPR 300
Query: 301 CAGCDELIFSNEYTQAENQNWHLKHFCCFDCDSILAGEIYVMVNDKPVCKPCYVKNHAVV 360
CAGCDELIFSNEYTQAENQNWHLKHFCCFDCDSILAGEIYVMVNDKPVCKPCYVKNHAVV
Sbjct: 301 CAGCDELIFSNEYTQAENQNWHLKHFCCFDCDSILAGEIYVMVNDKPVCKPCYVKNHAVV 360
Query: 361 CQGCHNAIDPEVQRVTYNNFSWHASTECFLCSCCSKCLIGQKFMPVEGMVFCSVECKKRM 420
CQGCHNAIDPEVQRVTYNNFSWHASTECFLCSCCSKCLIGQKFMPVEGMVFCSVECKKRM
Sbjct: 361 CQGCHNAIDPEVQRVTYNNFSWHASTECFLCSCCSKCLIGQKFMPVEGMVFCSVECKKRM 420
Query: 421 S 421
S
Sbjct: 421 S 421
>gi|23238188 testin isoform 2 [Homo sapiens]
Length = 412
Score = 891 bits (2303), Expect = 0.0
Identities = 412/412 (100%), Positives = 412/412 (100%)
Query: 10 MGLGHEQGFGAPCLKCKEKCEGFELHFWRKICRNCKCGQEEHDVLLSNEEDRKVGKLFED 69
MGLGHEQGFGAPCLKCKEKCEGFELHFWRKICRNCKCGQEEHDVLLSNEEDRKVGKLFED
Sbjct: 1 MGLGHEQGFGAPCLKCKEKCEGFELHFWRKICRNCKCGQEEHDVLLSNEEDRKVGKLFED 60
Query: 70 TKYTTLIAKLKSDGIPMYKRNVMILTNPVAAKKNVSINTVTYEWAPPVQNQALARQYMQM 129
TKYTTLIAKLKSDGIPMYKRNVMILTNPVAAKKNVSINTVTYEWAPPVQNQALARQYMQM
Sbjct: 61 TKYTTLIAKLKSDGIPMYKRNVMILTNPVAAKKNVSINTVTYEWAPPVQNQALARQYMQM 120
Query: 130 LPKEKQPVAGSEGAQYRKKQLAKQLPAHDQDPSKCHELSPREVKEMEQFVKKYKSEALGV 189
LPKEKQPVAGSEGAQYRKKQLAKQLPAHDQDPSKCHELSPREVKEMEQFVKKYKSEALGV
Sbjct: 121 LPKEKQPVAGSEGAQYRKKQLAKQLPAHDQDPSKCHELSPREVKEMEQFVKKYKSEALGV 180
Query: 190 GDVKLPCEMDAQGPKQMNIPGGDRSTPAAVGAMEDKSAEHKRTQYSCYCCKLSMKEGDPA 249
GDVKLPCEMDAQGPKQMNIPGGDRSTPAAVGAMEDKSAEHKRTQYSCYCCKLSMKEGDPA
Sbjct: 181 GDVKLPCEMDAQGPKQMNIPGGDRSTPAAVGAMEDKSAEHKRTQYSCYCCKLSMKEGDPA 240
Query: 250 IYAERAGYDKLWHPACFVCSTCHELLVDMIYFWKNEKLYCGRHYCDSEKPRCAGCDELIF 309
IYAERAGYDKLWHPACFVCSTCHELLVDMIYFWKNEKLYCGRHYCDSEKPRCAGCDELIF
Sbjct: 241 IYAERAGYDKLWHPACFVCSTCHELLVDMIYFWKNEKLYCGRHYCDSEKPRCAGCDELIF 300
Query: 310 SNEYTQAENQNWHLKHFCCFDCDSILAGEIYVMVNDKPVCKPCYVKNHAVVCQGCHNAID 369
SNEYTQAENQNWHLKHFCCFDCDSILAGEIYVMVNDKPVCKPCYVKNHAVVCQGCHNAID
Sbjct: 301 SNEYTQAENQNWHLKHFCCFDCDSILAGEIYVMVNDKPVCKPCYVKNHAVVCQGCHNAID 360
Query: 370 PEVQRVTYNNFSWHASTECFLCSCCSKCLIGQKFMPVEGMVFCSVECKKRMS 421
PEVQRVTYNNFSWHASTECFLCSCCSKCLIGQKFMPVEGMVFCSVECKKRMS
Sbjct: 361 PEVQRVTYNNFSWHASTECFLCSCCSKCLIGQKFMPVEGMVFCSVECKKRMS 412
>gi|7657309 LIM and cysteine-rich domains 1 [Homo sapiens]
Length = 365
Score = 386 bits (991), Expect = e-107
Identities = 182/356 (51%), Positives = 243/356 (68%), Gaps = 8/356 (2%)
Query: 2 DLENKVKKMGLGHEQGF-GAPCLKCKEKCEGFELHFWRKICRNCKCGQEEHDVLLSNEED 60
DL VKKM LG Q G CL CK C GFE H WRKIC++CKC QE+H + E+D
Sbjct: 7 DLNPGVKKMSLGQLQSARGVACLGCKGTCSGFEPHSWRKICKSCKCSQEDHCLTSDLEDD 66
Query: 61 RKVGKLFEDTKYTTLIAKLKS-DGIPMYKRNVMILTNPVAAKKNVSINTVTYEWAPPVQN 119
RK+G+L D+KY+TL A++K DGI +YKRN MI+TNP+A K+ + +T+TYEWAPP
Sbjct: 67 RKIGRLLMDSKYSTLTARVKGGDGIRIYKRNRMIMTNPIATGKDPTFDTITYEWAPPGVT 126
Query: 120 QALARQYMQMLPKEKQPVAGSEGAQYRKKQLAKQLPAHDQDPSKCHELSPREVKEMEQFV 179
Q L QYM+++PKEKQPV G+EGA YR++QL QLP +DQDPS+C L E+K ME+FV
Sbjct: 127 QKLGLQYMELIPKEKQPVTGTEGAFYRRRQLMHQLPIYDQDPSRCRGLLENELKLMEEFV 186
Query: 180 KKYKSEALGVGDVKLPCE--MDAQGPKQMNIPGGDRSTPAAV-GAMEDKSAEHKRTQYSC 236
K+YKSEALGVG+V LP + + + KQ P G +T A G++ D S K +Y C
Sbjct: 187 KQYKSEALGVGEVALPGQGGLPKEEGKQQEKPEGAETTAATTNGSLSDPS---KEVEYVC 243
Query: 237 YCCKLSMKEGDPAIYAERAGYDKLWHPACFVCSTCHELLVDMIYFWKNEKLYCGRHYCDS 296
CK + P +Y++RAGY+K WHP CFVC+ C E LVD+IYFWK+ +CGRHYC+S
Sbjct: 244 ELCKGAAPPDSPVVYSDRAGYNKQWHPTCFVCAKCSEPLVDLIYFWKDGAPWCGRHYCES 303
Query: 297 EKPRCAGCDELIFSNEYTQAENQNWHLKHFCCFDCDSILAGEIYVMVNDKPVCKPC 352
+PRC+GCDE+IF+ +Y + E+ WH KHF C C+ +L+G Y++ + +C C
Sbjct: 304 LRPRCSGCDEIIFAEDYQRVEDLAWHRKHFVCEGCEQLLSGRAYIVTKGQLLCPTC 359
>gi|7710129 LIM domain only 6 [Homo sapiens]
Length = 615
Score = 288 bits (738), Expect = 5e-78
Identities = 149/398 (37%), Positives = 205/398 (51%), Gaps = 55/398 (13%)
Query: 19 GAPCLKCKEKCEGFELHFWRKICRNCKCGQEEHDVLLSNEEDRKVGKLFEDTKYTTLIAK 78
G PC C+E+C GF LH WRKIC++CKC +EEH V + ++ + +
Sbjct: 24 GQPCNSCREQCPGFLLHGWRKICQHCKCPREEHAVHAVPVDLERI------------MCR 71
Query: 79 LKSDGIPMYKRNVMILTNPVAAKKNVSINTVTYEWAPPVQNQALARQYMQMLPKEKQPVA 138
L SD ++R+ + + A + Y W PP Q+ LP++K P
Sbjct: 72 LISD----FQRHSISDDDSGCASEE-------YAWVPPGLKPEQVYQFFSCLPEDKVPYV 120
Query: 139 GSEGAQYRKKQLAKQLPAHDQDPSKCHELSPREVKEMEQFVKKYKSEALGVGDVKLPCEM 198
S G +YR KQL QLP HD + C L E KE+ F ++ K E LG G V++
Sbjct: 121 NSPGEKYRIKQLLHQLPPHDSEAQYCTALEEEEKKELRAFSQQRKRENLGRGIVRI---- 176
Query: 199 DAQGPKQMNIPGGDRSTPAAVGAMEDKSAEHKRTQYSCYCCKLSMKEGDPAIYAERAGYD 258
P + T C C + GD A++A RAG
Sbjct: 177 ----------------FPVTI------------TGAICEECGKQIGGGDIAVFASRAGLG 208
Query: 259 KLWHPACFVCSTCHELLVDMIYFWKNEKLYCGRHYCDSEKPRCAGCDELIFSNEYTQAEN 318
WHP CFVC+TC ELLVD+IYF+ K+YCGRH+ + +PRC CDE+IFS E T+AE
Sbjct: 209 ACWHPQCFVCTTCQELLVDLIYFYHVGKVYCGRHHAECLRPRCQACDEIIFSPECTEAEG 268
Query: 319 QNWHLKHFCCFDCDSILAGEIYVMVNDKPVCKPCYVKNHAVVCQGCHNAIDPEVQRVTYN 378
++WH+ HFCCF+C++ L G+ YVM +P C CY HA C GC I + ++ Y
Sbjct: 269 RHWHMDHFCCFECEASLGGQRYVMRQSRPHCCACYEARHAEYCDGCGEHIGLDQGQMAYE 328
Query: 379 NFSWHASTECFLCSCCSKCLIGQKFMPVEGMVFCSVEC 416
WHAS CF CS C + L+G+ F+P G++FCS C
Sbjct: 329 GQHWHASDRCFCCSRCGRALLGRPFLPRRGLIFCSRAC 366
>gi|38524620 prickle-like 2 [Homo sapiens]
Length = 844
Score = 255 bits (652), Expect = 5e-68
Identities = 119/306 (38%), Positives = 171/306 (55%), Gaps = 32/306 (10%)
Query: 111 YEWAPPVQNQALARQYMQMLPKEKQPVAGSEGAQYRKKQLAKQLPAHDQDPSKCHELSPR 170
Y W PP QY LP+EK P S G + R KQL QLP HD + C+ L
Sbjct: 37 YAWVPPGLKPEQVHQYYSCLPEEKVPYVNSPGEKLRIKQLLHQLPPHDNEVRYCNSLDEE 96
Query: 171 EVKEMEQFVKKYKSEALGVGDVKLPCEMDAQGPKQMNIPGGDRSTPAAVGAMEDKSAEHK 230
E +E++ F + K E LG G+V+ P + + G
Sbjct: 97 EKRELKLFSSQRKRENLGRGNVR---------PFPVTMTGA------------------- 128
Query: 231 RTQYSCYCCKLSMKEGDPAIYAERAGYDKLWHPACFVCSTCHELLVDMIYFWKNEKLYCG 290
C C + GD A++A RAG+ WHP CFVC+ C+ELLVD+IYF+++ K+YCG
Sbjct: 129 ----ICEQCGGQINGGDIAVFASRAGHGVCWHPPCFVCTVCNELLVDLIYFYQDGKIYCG 184
Query: 291 RHYCDSEKPRCAGCDELIFSNEYTQAENQNWHLKHFCCFDCDSILAGEIYVMVNDKPVCK 350
RH+ + KPRCA CDE+IF++E T+AE ++WH+KHFCCF+C+++L G+ Y+M +P C
Sbjct: 185 RHHAECLKPRCAACDEIIFADECTEAEGRHWHMKHFCCFECETVLGGQRYIMKEGRPYCC 244
Query: 351 PCYVKNHAVVCQGCHNAIDPEVQRVTYNNFSWHASTECFLCSCCSKCLIGQKFMPVEGMV 410
C+ +A C C I + ++TY+ WHA+ CF C+ C K L+G+ F+P +G +
Sbjct: 245 HCFESLYAEYCDTCAQHIGIDQGQMTYDGQHWHATETCFCCAHCKKSLLGRPFLPKQGQI 304
Query: 411 FCSVEC 416
FCS C
Sbjct: 305 FCSRAC 310
Score = 31.6 bits (70), Expect = 1.4
Identities = 30/125 (24%), Positives = 46/125 (36%), Gaps = 34/125 (27%)
Query: 221 AMEDKSAEHKRTQYSCYCC----------KLSMKEGDP-------AIYAE---------- 253
A E AE + +CC + MKEG P ++YAE
Sbjct: 204 ADECTEAEGRHWHMKHFCCFECETVLGGQRYIMKEGRPYCCHCFESLYAEYCDTCAQHIG 263
Query: 254 ----RAGYD-KLWHPA--CFVCSTCHELLVDMIYFWKNEKLYCGRHYCDSEKPRCAGCDE 306
+ YD + WH CF C+ C + L+ + K +++C R E P + +
Sbjct: 264 IDQGQMTYDGQHWHATETCFCCAHCKKSLLGRPFLPKQGQIFCSRACSAGEDPNGSDSSD 323
Query: 307 LIFSN 311
F N
Sbjct: 324 SAFQN 328
>gi|222136684 prickle homolog 1 [Homo sapiens]
Length = 831
Score = 252 bits (643), Expect = 5e-67
Identities = 119/306 (38%), Positives = 173/306 (56%), Gaps = 32/306 (10%)
Query: 111 YEWAPPVQNQALARQYMQMLPKEKQPVAGSEGAQYRKKQLAKQLPAHDQDPSKCHELSPR 170
Y W PP + Y LP+EK P S G ++R KQL QLP HD + C LS
Sbjct: 33 YAWVPPGLRPEQIQLYFACLPEEKVPYVNSPGEKHRIKQLLYQLPPHDNEVRYCQSLSEE 92
Query: 171 EVKEMEQFVKKYKSEALGVGDVKLPCEMDAQGPKQMNIPGGDRSTPAAVGAMEDKSAEHK 230
E KE++ F + K EALG G +KL R+ AV
Sbjct: 93 EKKELQVFSAQRKKEALGRGTIKLL----------------SRAVMHAV----------- 125
Query: 231 RTQYSCYCCKLSMKEGDPAIYAERAGYDKLWHPACFVCSTCHELLVDMIYFWKNEKLYCG 290
C C L + G+ A++A RAG WHP+CFVC TC+ELLVD+IYF+++ K++CG
Sbjct: 126 -----CEQCGLKINGGEVAVFASRAGPGVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCG 180
Query: 291 RHYCDSEKPRCAGCDELIFSNEYTQAENQNWHLKHFCCFDCDSILAGEIYVMVNDKPVCK 350
RH+ + KPRC+ CDE+IF++E T+AE ++WH+KHFCC +C+++L G+ Y+M + +P C
Sbjct: 181 RHHAELLKPRCSACDEIIFADECTEAEGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCC 240
Query: 351 PCYVKNHAVVCQGCHNAIDPEVQRVTYNNFSWHASTECFLCSCCSKCLIGQKFMPVEGMV 410
C+ +A C+ C I + ++TY+ WHA+ CF C+ C L+G F+P +G +
Sbjct: 241 GCFESLYAEYCETCGEHIGVDHAQMTYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQI 300
Query: 411 FCSVEC 416
+CS C
Sbjct: 301 YCSKTC 306
>gi|222136682 prickle homolog 1 [Homo sapiens]
Length = 831
Score = 252 bits (643), Expect = 5e-67
Identities = 119/306 (38%), Positives = 173/306 (56%), Gaps = 32/306 (10%)
Query: 111 YEWAPPVQNQALARQYMQMLPKEKQPVAGSEGAQYRKKQLAKQLPAHDQDPSKCHELSPR 170
Y W PP + Y LP+EK P S G ++R KQL QLP HD + C LS
Sbjct: 33 YAWVPPGLRPEQIQLYFACLPEEKVPYVNSPGEKHRIKQLLYQLPPHDNEVRYCQSLSEE 92
Query: 171 EVKEMEQFVKKYKSEALGVGDVKLPCEMDAQGPKQMNIPGGDRSTPAAVGAMEDKSAEHK 230
E KE++ F + K EALG G +KL R+ AV
Sbjct: 93 EKKELQVFSAQRKKEALGRGTIKLL----------------SRAVMHAV----------- 125
Query: 231 RTQYSCYCCKLSMKEGDPAIYAERAGYDKLWHPACFVCSTCHELLVDMIYFWKNEKLYCG 290
C C L + G+ A++A RAG WHP+CFVC TC+ELLVD+IYF+++ K++CG
Sbjct: 126 -----CEQCGLKINGGEVAVFASRAGPGVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCG 180
Query: 291 RHYCDSEKPRCAGCDELIFSNEYTQAENQNWHLKHFCCFDCDSILAGEIYVMVNDKPVCK 350
RH+ + KPRC+ CDE+IF++E T+AE ++WH+KHFCC +C+++L G+ Y+M + +P C
Sbjct: 181 RHHAELLKPRCSACDEIIFADECTEAEGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCC 240
Query: 351 PCYVKNHAVVCQGCHNAIDPEVQRVTYNNFSWHASTECFLCSCCSKCLIGQKFMPVEGMV 410
C+ +A C+ C I + ++TY+ WHA+ CF C+ C L+G F+P +G +
Sbjct: 241 GCFESLYAEYCETCGEHIGVDHAQMTYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQI 300
Query: 411 FCSVEC 416
+CS C
Sbjct: 301 YCSKTC 306
>gi|222136680 prickle homolog 1 [Homo sapiens]
Length = 831
Score = 252 bits (643), Expect = 5e-67
Identities = 119/306 (38%), Positives = 173/306 (56%), Gaps = 32/306 (10%)
Query: 111 YEWAPPVQNQALARQYMQMLPKEKQPVAGSEGAQYRKKQLAKQLPAHDQDPSKCHELSPR 170
Y W PP + Y LP+EK P S G ++R KQL QLP HD + C LS
Sbjct: 33 YAWVPPGLRPEQIQLYFACLPEEKVPYVNSPGEKHRIKQLLYQLPPHDNEVRYCQSLSEE 92
Query: 171 EVKEMEQFVKKYKSEALGVGDVKLPCEMDAQGPKQMNIPGGDRSTPAAVGAMEDKSAEHK 230
E KE++ F + K EALG G +KL R+ AV
Sbjct: 93 EKKELQVFSAQRKKEALGRGTIKLL----------------SRAVMHAV----------- 125
Query: 231 RTQYSCYCCKLSMKEGDPAIYAERAGYDKLWHPACFVCSTCHELLVDMIYFWKNEKLYCG 290
C C L + G+ A++A RAG WHP+CFVC TC+ELLVD+IYF+++ K++CG
Sbjct: 126 -----CEQCGLKINGGEVAVFASRAGPGVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCG 180
Query: 291 RHYCDSEKPRCAGCDELIFSNEYTQAENQNWHLKHFCCFDCDSILAGEIYVMVNDKPVCK 350
RH+ + KPRC+ CDE+IF++E T+AE ++WH+KHFCC +C+++L G+ Y+M + +P C
Sbjct: 181 RHHAELLKPRCSACDEIIFADECTEAEGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCC 240
Query: 351 PCYVKNHAVVCQGCHNAIDPEVQRVTYNNFSWHASTECFLCSCCSKCLIGQKFMPVEGMV 410
C+ +A C+ C I + ++TY+ WHA+ CF C+ C L+G F+P +G +
Sbjct: 241 GCFESLYAEYCETCGEHIGVDHAQMTYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQI 300
Query: 411 FCSVEC 416
+CS C
Sbjct: 301 YCSKTC 306
>gi|222136678 prickle homolog 1 [Homo sapiens]
Length = 831
Score = 252 bits (643), Expect = 5e-67
Identities = 119/306 (38%), Positives = 173/306 (56%), Gaps = 32/306 (10%)
Query: 111 YEWAPPVQNQALARQYMQMLPKEKQPVAGSEGAQYRKKQLAKQLPAHDQDPSKCHELSPR 170
Y W PP + Y LP+EK P S G ++R KQL QLP HD + C LS
Sbjct: 33 YAWVPPGLRPEQIQLYFACLPEEKVPYVNSPGEKHRIKQLLYQLPPHDNEVRYCQSLSEE 92
Query: 171 EVKEMEQFVKKYKSEALGVGDVKLPCEMDAQGPKQMNIPGGDRSTPAAVGAMEDKSAEHK 230
E KE++ F + K EALG G +KL R+ AV
Sbjct: 93 EKKELQVFSAQRKKEALGRGTIKLL----------------SRAVMHAV----------- 125
Query: 231 RTQYSCYCCKLSMKEGDPAIYAERAGYDKLWHPACFVCSTCHELLVDMIYFWKNEKLYCG 290
C C L + G+ A++A RAG WHP+CFVC TC+ELLVD+IYF+++ K++CG
Sbjct: 126 -----CEQCGLKINGGEVAVFASRAGPGVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCG 180
Query: 291 RHYCDSEKPRCAGCDELIFSNEYTQAENQNWHLKHFCCFDCDSILAGEIYVMVNDKPVCK 350
RH+ + KPRC+ CDE+IF++E T+AE ++WH+KHFCC +C+++L G+ Y+M + +P C
Sbjct: 181 RHHAELLKPRCSACDEIIFADECTEAEGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCC 240
Query: 351 PCYVKNHAVVCQGCHNAIDPEVQRVTYNNFSWHASTECFLCSCCSKCLIGQKFMPVEGMV 410
C+ +A C+ C I + ++TY+ WHA+ CF C+ C L+G F+P +G +
Sbjct: 241 GCFESLYAEYCETCGEHIGVDHAQMTYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQI 300
Query: 411 FCSVEC 416
+CS C
Sbjct: 301 YCSKTC 306
>gi|118722347 over-expressed breast tumor protein [Homo sapiens]
Length = 384
Score = 142 bits (357), Expect = 7e-34
Identities = 71/209 (33%), Positives = 102/209 (48%), Gaps = 32/209 (15%)
Query: 150 LAKQLPAHDQDPSKCHELSPREVKEMEQFVKKYKSEALGVGDVKLPCEMDAQGPKQMNIP 209
L +QLP D D C L E E++ F + K EALG QG ++ +P
Sbjct: 70 LLQQLPPQDIDERYCLALGEEERAELQLFCARRKQEALG------------QGVARLVLP 117
Query: 210 GGDRSTPAAVGAMEDKSAEHKRTQYSCYCCKLSMKEGDPAIYAERAGYDKLWHPACFVCS 269
K ++C C+ +K G+ ++A RAG + WH CF C
Sbjct: 118 --------------------KLEGHTCEKCRELLKPGEYGVFAARAGEQRCWHQPCFACQ 157
Query: 270 TCHELLVDMIYFWKNEKLYCGRHYCDSEKPRCAGCDELIFSNEYTQAENQNWHLKHFCCF 329
C + L+++IYF+ + +LYCGRH+ + +PRC CD+LIFS T+AE Q WH HFCC
Sbjct: 158 ACGQALINLIYFYHDGQLYCGRHHAELLRPRCPACDQLIFSWRCTEAEGQRWHENHFCCQ 217
Query: 330 DCDSILAGEIYVMVNDKPVCKPCYVKNHA 358
DC L G Y + P C C+ ++
Sbjct: 218 DCAGPLGGGRYALPGGSPCCPSCFENRYS 246
>gi|87159836 four and a half LIM domains 2 [Homo sapiens]
Length = 279
Score = 100 bits (249), Expect = 2e-21
Identities = 50/156 (32%), Positives = 73/156 (46%), Gaps = 5/156 (3%)
Query: 258 DKLWHPACFVCSTCHELLVDMIYFWKNEKLYCGRHYCDSEKPRCAGCDELIF-SNEYTQA 316
D+ WH ACF CS C LVD + K ++L C Y + +C C + I +
Sbjct: 58 DRHWHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEY 117
Query: 317 ENQNWHLKHFCCFDCDSILAGEIYVMVNDKPVCKPCYVKNHAVVCQGCHNAIDPEVQRVT 376
+ +WH F C C + + ++ +++ C PCY K HA+ C C I VT
Sbjct: 118 KGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPI--TTGGVT 175
Query: 377 YNNFSWHASTECFLCSCCSKCLIGQKFMPVEGMVFC 412
Y WH ECF+C+ C K L GQ+F + +C
Sbjct: 176 YREQPWH--KECFVCTACRKQLSGQRFTARDDFAYC 209
Score = 81.3 bits (199), Expect = 2e-15
Identities = 50/190 (26%), Positives = 83/190 (43%), Gaps = 12/190 (6%)
Query: 233 QYSCYC--CKLSMKEGDPAIYAERAGYDKLWHPACFVCSTCHELLVDMIYFWKNEKLYCG 290
+YS C CK ++ G + + + WH CF+C C + + + K+ + +C
Sbjct: 96 EYSSKCQECKKTIMPGTRKMEYKGSS----WHETCFICHRCQQPIGTKSFIPKDNQNFCV 151
Query: 291 RHYCDSEKPRCAGCDELIFSNEYTQAENQNWHLKHFCCFDCDSILAGEIYVMVNDKPVCK 350
Y +C C + I + T E Q WH + F C C L+G+ + +D C
Sbjct: 152 PCYEKQHAMQCVQCKKPITTGGVTYRE-QPWHKECFVCTACRKQLSGQRFTARDDFAYCL 210
Query: 351 PCYVKNHAVVCQGCHNAID--PEVQRVTYNNFSWHASTECFLCSCCSKCLIGQKFMPVEG 408
C+ +A C GC N I + +++ WH +CF C CS L+G+ F+
Sbjct: 211 NCFCDLYAKKCAGCTNPISGLGGTKYISFEERQWH--NDCFNCKKCSLSLVGRGFLTERD 268
Query: 409 MVFCSVECKK 418
+ C +C K
Sbjct: 269 DILCP-DCGK 277
Score = 75.5 bits (184), Expect = 9e-14
Identities = 41/159 (25%), Positives = 69/159 (43%), Gaps = 26/159 (16%)
Query: 284 NEKLYCGRHYCDSEKPRCAGCDELIFSNEYTQA-------------ENQNWHLKHFCCFD 330
NE L+ ++ E P C C E +F+N + ++++WH F C
Sbjct: 11 NESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWHEACFHCSQ 70
Query: 331 CDSILAGEIYVMVNDKPVCKPCYVKNHAVVCQGCHNAIDPEVQRVTYNNFSWHASTECFL 390
C + L + + D+ +C CY ++ CQ C I P +++ Y SWH + CF+
Sbjct: 71 CRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSWHET--CFI 128
Query: 391 CSCCSKCLIGQKFMPVEGMVFC-----------SVECKK 418
C C + + + F+P + FC V+CKK
Sbjct: 129 CHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKK 167
Score = 63.2 bits (152), Expect = 4e-10
Identities = 36/126 (28%), Positives = 52/126 (41%), Gaps = 9/126 (7%)
Query: 230 KRTQYSCYCCKLSMKEGDPAIYAERAGYDKLWHPACFVCSTCHELLVDMIYFWKNEKLYC 289
K+ C CK + G Y E+ WH CFVC+ C + L + +++ YC
Sbjct: 156 KQHAMQCVQCKKPITTGG-VTYREQP-----WHKECFVCTACRKQLSGQRFTARDDFAYC 209
Query: 290 GRHYCDSEKPRCAGCDELIF---SNEYTQAENQNWHLKHFCCFDCDSILAGEIYVMVNDK 346
+CD +CAGC I +Y E + WH F C C L G ++ D
Sbjct: 210 LNCFCDLYAKKCAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLTERDD 269
Query: 347 PVCKPC 352
+C C
Sbjct: 270 ILCPDC 275
Score = 55.5 bits (132), Expect = 9e-08
Identities = 25/90 (27%), Positives = 43/90 (47%), Gaps = 2/90 (2%)
Query: 324 KHFCCFDCDSILAGEIYVMVNDKPVCKPCYVKNHAVVCQGCHNAIDPEVQRVTYNNFSWH 383
+ F C C+ L G+ Y++ + P C C+ A C+ C I + + ++Y + WH
Sbjct: 3 ERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWH 62
Query: 384 ASTECFLCSCCSKCLIGQKFMPVEGMVFCS 413
+ CF CS C L+ + F E + C+
Sbjct: 63 EA--CFHCSQCRNSLVDKPFAAKEDQLLCT 90
>gi|87159834 four and a half LIM domains 2 [Homo sapiens]
Length = 279
Score = 100 bits (249), Expect = 2e-21
Identities = 50/156 (32%), Positives = 73/156 (46%), Gaps = 5/156 (3%)
Query: 258 DKLWHPACFVCSTCHELLVDMIYFWKNEKLYCGRHYCDSEKPRCAGCDELIF-SNEYTQA 316
D+ WH ACF CS C LVD + K ++L C Y + +C C + I +
Sbjct: 58 DRHWHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEY 117
Query: 317 ENQNWHLKHFCCFDCDSILAGEIYVMVNDKPVCKPCYVKNHAVVCQGCHNAIDPEVQRVT 376
+ +WH F C C + + ++ +++ C PCY K HA+ C C I VT
Sbjct: 118 KGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPI--TTGGVT 175
Query: 377 YNNFSWHASTECFLCSCCSKCLIGQKFMPVEGMVFC 412
Y WH ECF+C+ C K L GQ+F + +C
Sbjct: 176 YREQPWH--KECFVCTACRKQLSGQRFTARDDFAYC 209
Score = 81.3 bits (199), Expect = 2e-15
Identities = 50/190 (26%), Positives = 83/190 (43%), Gaps = 12/190 (6%)
Query: 233 QYSCYC--CKLSMKEGDPAIYAERAGYDKLWHPACFVCSTCHELLVDMIYFWKNEKLYCG 290
+YS C CK ++ G + + + WH CF+C C + + + K+ + +C
Sbjct: 96 EYSSKCQECKKTIMPGTRKMEYKGSS----WHETCFICHRCQQPIGTKSFIPKDNQNFCV 151
Query: 291 RHYCDSEKPRCAGCDELIFSNEYTQAENQNWHLKHFCCFDCDSILAGEIYVMVNDKPVCK 350
Y +C C + I + T E Q WH + F C C L+G+ + +D C
Sbjct: 152 PCYEKQHAMQCVQCKKPITTGGVTYRE-QPWHKECFVCTACRKQLSGQRFTARDDFAYCL 210
Query: 351 PCYVKNHAVVCQGCHNAID--PEVQRVTYNNFSWHASTECFLCSCCSKCLIGQKFMPVEG 408
C+ +A C GC N I + +++ WH +CF C CS L+G+ F+
Sbjct: 211 NCFCDLYAKKCAGCTNPISGLGGTKYISFEERQWH--NDCFNCKKCSLSLVGRGFLTERD 268
Query: 409 MVFCSVECKK 418
+ C +C K
Sbjct: 269 DILCP-DCGK 277
Score = 75.5 bits (184), Expect = 9e-14
Identities = 41/159 (25%), Positives = 69/159 (43%), Gaps = 26/159 (16%)
Query: 284 NEKLYCGRHYCDSEKPRCAGCDELIFSNEYTQA-------------ENQNWHLKHFCCFD 330
NE L+ ++ E P C C E +F+N + ++++WH F C
Sbjct: 11 NESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWHEACFHCSQ 70
Query: 331 CDSILAGEIYVMVNDKPVCKPCYVKNHAVVCQGCHNAIDPEVQRVTYNNFSWHASTECFL 390
C + L + + D+ +C CY ++ CQ C I P +++ Y SWH + CF+
Sbjct: 71 CRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSWHET--CFI 128
Query: 391 CSCCSKCLIGQKFMPVEGMVFC-----------SVECKK 418
C C + + + F+P + FC V+CKK
Sbjct: 129 CHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKK 167
Score = 63.2 bits (152), Expect = 4e-10
Identities = 36/126 (28%), Positives = 52/126 (41%), Gaps = 9/126 (7%)
Query: 230 KRTQYSCYCCKLSMKEGDPAIYAERAGYDKLWHPACFVCSTCHELLVDMIYFWKNEKLYC 289
K+ C CK + G Y E+ WH CFVC+ C + L + +++ YC
Sbjct: 156 KQHAMQCVQCKKPITTGG-VTYREQP-----WHKECFVCTACRKQLSGQRFTARDDFAYC 209
Query: 290 GRHYCDSEKPRCAGCDELIF---SNEYTQAENQNWHLKHFCCFDCDSILAGEIYVMVNDK 346
+CD +CAGC I +Y E + WH F C C L G ++ D
Sbjct: 210 LNCFCDLYAKKCAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLTERDD 269
Query: 347 PVCKPC 352
+C C
Sbjct: 270 ILCPDC 275
Score = 55.5 bits (132), Expect = 9e-08
Identities = 25/90 (27%), Positives = 43/90 (47%), Gaps = 2/90 (2%)
Query: 324 KHFCCFDCDSILAGEIYVMVNDKPVCKPCYVKNHAVVCQGCHNAIDPEVQRVTYNNFSWH 383
+ F C C+ L G+ Y++ + P C C+ A C+ C I + + ++Y + WH
Sbjct: 3 ERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWH 62
Query: 384 ASTECFLCSCCSKCLIGQKFMPVEGMVFCS 413
+ CF CS C L+ + F E + C+
Sbjct: 63 EA--CFHCSQCRNSLVDKPFAAKEDQLLCT 90
>gi|42403575 four and a half LIM domains 2 [Homo sapiens]
Length = 279
Score = 100 bits (249), Expect = 2e-21
Identities = 50/156 (32%), Positives = 73/156 (46%), Gaps = 5/156 (3%)
Query: 258 DKLWHPACFVCSTCHELLVDMIYFWKNEKLYCGRHYCDSEKPRCAGCDELIF-SNEYTQA 316
D+ WH ACF CS C LVD + K ++L C Y + +C C + I +
Sbjct: 58 DRHWHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEY 117
Query: 317 ENQNWHLKHFCCFDCDSILAGEIYVMVNDKPVCKPCYVKNHAVVCQGCHNAIDPEVQRVT 376
+ +WH F C C + + ++ +++ C PCY K HA+ C C I VT
Sbjct: 118 KGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPI--TTGGVT 175
Query: 377 YNNFSWHASTECFLCSCCSKCLIGQKFMPVEGMVFC 412
Y WH ECF+C+ C K L GQ+F + +C
Sbjct: 176 YREQPWH--KECFVCTACRKQLSGQRFTARDDFAYC 209
Score = 81.3 bits (199), Expect = 2e-15
Identities = 50/190 (26%), Positives = 83/190 (43%), Gaps = 12/190 (6%)
Query: 233 QYSCYC--CKLSMKEGDPAIYAERAGYDKLWHPACFVCSTCHELLVDMIYFWKNEKLYCG 290
+YS C CK ++ G + + + WH CF+C C + + + K+ + +C
Sbjct: 96 EYSSKCQECKKTIMPGTRKMEYKGSS----WHETCFICHRCQQPIGTKSFIPKDNQNFCV 151
Query: 291 RHYCDSEKPRCAGCDELIFSNEYTQAENQNWHLKHFCCFDCDSILAGEIYVMVNDKPVCK 350
Y +C C + I + T E Q WH + F C C L+G+ + +D C
Sbjct: 152 PCYEKQHAMQCVQCKKPITTGGVTYRE-QPWHKECFVCTACRKQLSGQRFTARDDFAYCL 210
Query: 351 PCYVKNHAVVCQGCHNAID--PEVQRVTYNNFSWHASTECFLCSCCSKCLIGQKFMPVEG 408
C+ +A C GC N I + +++ WH +CF C CS L+G+ F+
Sbjct: 211 NCFCDLYAKKCAGCTNPISGLGGTKYISFEERQWH--NDCFNCKKCSLSLVGRGFLTERD 268
Query: 409 MVFCSVECKK 418
+ C +C K
Sbjct: 269 DILCP-DCGK 277
Score = 75.5 bits (184), Expect = 9e-14
Identities = 41/159 (25%), Positives = 69/159 (43%), Gaps = 26/159 (16%)
Query: 284 NEKLYCGRHYCDSEKPRCAGCDELIFSNEYTQA-------------ENQNWHLKHFCCFD 330
NE L+ ++ E P C C E +F+N + ++++WH F C
Sbjct: 11 NESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWHEACFHCSQ 70
Query: 331 CDSILAGEIYVMVNDKPVCKPCYVKNHAVVCQGCHNAIDPEVQRVTYNNFSWHASTECFL 390
C + L + + D+ +C CY ++ CQ C I P +++ Y SWH + CF+
Sbjct: 71 CRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSWHET--CFI 128
Query: 391 CSCCSKCLIGQKFMPVEGMVFC-----------SVECKK 418
C C + + + F+P + FC V+CKK
Sbjct: 129 CHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKK 167
Score = 63.2 bits (152), Expect = 4e-10
Identities = 36/126 (28%), Positives = 52/126 (41%), Gaps = 9/126 (7%)
Query: 230 KRTQYSCYCCKLSMKEGDPAIYAERAGYDKLWHPACFVCSTCHELLVDMIYFWKNEKLYC 289
K+ C CK + G Y E+ WH CFVC+ C + L + +++ YC
Sbjct: 156 KQHAMQCVQCKKPITTGG-VTYREQP-----WHKECFVCTACRKQLSGQRFTARDDFAYC 209
Query: 290 GRHYCDSEKPRCAGCDELIF---SNEYTQAENQNWHLKHFCCFDCDSILAGEIYVMVNDK 346
+CD +CAGC I +Y E + WH F C C L G ++ D
Sbjct: 210 LNCFCDLYAKKCAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLTERDD 269
Query: 347 PVCKPC 352
+C C
Sbjct: 270 ILCPDC 275
Score = 55.5 bits (132), Expect = 9e-08
Identities = 25/90 (27%), Positives = 43/90 (47%), Gaps = 2/90 (2%)
Query: 324 KHFCCFDCDSILAGEIYVMVNDKPVCKPCYVKNHAVVCQGCHNAIDPEVQRVTYNNFSWH 383
+ F C C+ L G+ Y++ + P C C+ A C+ C I + + ++Y + WH
Sbjct: 3 ERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWH 62
Query: 384 ASTECFLCSCCSKCLIGQKFMPVEGMVFCS 413
+ CF CS C L+ + F E + C+
Sbjct: 63 EA--CFHCSQCRNSLVDKPFAAKEDQLLCT 90
>gi|87159832 four and a half LIM domains 2 [Homo sapiens]
Length = 279
Score = 100 bits (249), Expect = 2e-21
Identities = 50/156 (32%), Positives = 73/156 (46%), Gaps = 5/156 (3%)
Query: 258 DKLWHPACFVCSTCHELLVDMIYFWKNEKLYCGRHYCDSEKPRCAGCDELIF-SNEYTQA 316
D+ WH ACF CS C LVD + K ++L C Y + +C C + I +
Sbjct: 58 DRHWHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEY 117
Query: 317 ENQNWHLKHFCCFDCDSILAGEIYVMVNDKPVCKPCYVKNHAVVCQGCHNAIDPEVQRVT 376
+ +WH F C C + + ++ +++ C PCY K HA+ C C I VT
Sbjct: 118 KGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPI--TTGGVT 175
Query: 377 YNNFSWHASTECFLCSCCSKCLIGQKFMPVEGMVFC 412
Y WH ECF+C+ C K L GQ+F + +C
Sbjct: 176 YREQPWH--KECFVCTACRKQLSGQRFTARDDFAYC 209
Score = 81.3 bits (199), Expect = 2e-15
Identities = 50/190 (26%), Positives = 83/190 (43%), Gaps = 12/190 (6%)
Query: 233 QYSCYC--CKLSMKEGDPAIYAERAGYDKLWHPACFVCSTCHELLVDMIYFWKNEKLYCG 290
+YS C CK ++ G + + + WH CF+C C + + + K+ + +C
Sbjct: 96 EYSSKCQECKKTIMPGTRKMEYKGSS----WHETCFICHRCQQPIGTKSFIPKDNQNFCV 151
Query: 291 RHYCDSEKPRCAGCDELIFSNEYTQAENQNWHLKHFCCFDCDSILAGEIYVMVNDKPVCK 350
Y +C C + I + T E Q WH + F C C L+G+ + +D C
Sbjct: 152 PCYEKQHAMQCVQCKKPITTGGVTYRE-QPWHKECFVCTACRKQLSGQRFTARDDFAYCL 210
Query: 351 PCYVKNHAVVCQGCHNAID--PEVQRVTYNNFSWHASTECFLCSCCSKCLIGQKFMPVEG 408
C+ +A C GC N I + +++ WH +CF C CS L+G+ F+
Sbjct: 211 NCFCDLYAKKCAGCTNPISGLGGTKYISFEERQWH--NDCFNCKKCSLSLVGRGFLTERD 268
Query: 409 MVFCSVECKK 418
+ C +C K
Sbjct: 269 DILCP-DCGK 277
Score = 75.5 bits (184), Expect = 9e-14
Identities = 41/159 (25%), Positives = 69/159 (43%), Gaps = 26/159 (16%)
Query: 284 NEKLYCGRHYCDSEKPRCAGCDELIFSNEYTQA-------------ENQNWHLKHFCCFD 330
NE L+ ++ E P C C E +F+N + ++++WH F C
Sbjct: 11 NESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWHEACFHCSQ 70
Query: 331 CDSILAGEIYVMVNDKPVCKPCYVKNHAVVCQGCHNAIDPEVQRVTYNNFSWHASTECFL 390
C + L + + D+ +C CY ++ CQ C I P +++ Y SWH + CF+
Sbjct: 71 CRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSWHET--CFI 128
Query: 391 CSCCSKCLIGQKFMPVEGMVFC-----------SVECKK 418
C C + + + F+P + FC V+CKK
Sbjct: 129 CHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKK 167
Score = 63.2 bits (152), Expect = 4e-10
Identities = 36/126 (28%), Positives = 52/126 (41%), Gaps = 9/126 (7%)
Query: 230 KRTQYSCYCCKLSMKEGDPAIYAERAGYDKLWHPACFVCSTCHELLVDMIYFWKNEKLYC 289
K+ C CK + G Y E+ WH CFVC+ C + L + +++ YC
Sbjct: 156 KQHAMQCVQCKKPITTGG-VTYREQP-----WHKECFVCTACRKQLSGQRFTARDDFAYC 209
Query: 290 GRHYCDSEKPRCAGCDELIF---SNEYTQAENQNWHLKHFCCFDCDSILAGEIYVMVNDK 346
+CD +CAGC I +Y E + WH F C C L G ++ D
Sbjct: 210 LNCFCDLYAKKCAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLTERDD 269
Query: 347 PVCKPC 352
+C C
Sbjct: 270 ILCPDC 275
Score = 55.5 bits (132), Expect = 9e-08
Identities = 25/90 (27%), Positives = 43/90 (47%), Gaps = 2/90 (2%)
Query: 324 KHFCCFDCDSILAGEIYVMVNDKPVCKPCYVKNHAVVCQGCHNAIDPEVQRVTYNNFSWH 383
+ F C C+ L G+ Y++ + P C C+ A C+ C I + + ++Y + WH
Sbjct: 3 ERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWH 62
Query: 384 ASTECFLCSCCSKCLIGQKFMPVEGMVFCS 413
+ CF CS C L+ + F E + C+
Sbjct: 63 EA--CFHCSQCRNSLVDKPFAAKEDQLLCT 90
>gi|228480213 four and a half LIM domains 1 isoform 2 [Homo sapiens]
Length = 280
Score = 93.6 bits (231), Expect = 3e-19
Identities = 47/162 (29%), Positives = 77/162 (47%), Gaps = 6/162 (3%)
Query: 258 DKLWHPACFVCSTCHELLVDMIYFWKNEKLYCGRHYCDSEKPRCAGC-DELIFSNEYTQA 316
++ WH CF C+ C L + + K+ K+ C + + P+C GC ++ ++ +
Sbjct: 58 NRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEY 117
Query: 317 ENQNWHLKHFCCFDCDSILAGEIYVMVNDKPVCKPCYVKNHAVVCQGCHNAIDPEVQRVT 376
+ WH F C +C ++ + + C C+ A C C+ AI +T
Sbjct: 118 KGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITS--GGIT 175
Query: 377 YNNFSWHASTECFLCSCCSKCLIGQKFMPVEGMVFCSVECKK 418
Y + WHA +CF+C CSK L GQ+F VE +C V+C K
Sbjct: 176 YQDQPWHA--DCFVCVTCSKKLAGQRFTAVEDQYYC-VDCYK 214
Score = 92.0 bits (227), Expect = 9e-19
Identities = 53/164 (32%), Positives = 74/164 (45%), Gaps = 7/164 (4%)
Query: 260 LWHPACFVCSTCHELLVDMIYFWKNEKLYCGRHYCDSEKPRCAGCDELIFSNEYTQAENQ 319
+WH CF CS C +++ +F K E YC + C C++ I S T ++Q
Sbjct: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITY-QDQ 179
Query: 320 NWHLKHFCCFDCDSILAGEIYVMVNDKPVCKPCYVKNHAVVCQGCHNAI---DPEVQRVT 376
WH F C C LAG+ + V D+ C CY A C GC N I V
Sbjct: 180 PWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVVA 239
Query: 377 YNNFSWHASTECFLCSCCSKCLIGQKFMPVEGMVFCSVECKKRM 420
Y SWH CF C CS L ++F+ + V+C +C K++
Sbjct: 240 YEGQSWH--DYCFHCKKCSVNLANKRFVFHQEQVYCP-DCAKKL 280
Score = 64.3 bits (155), Expect = 2e-10
Identities = 44/152 (28%), Positives = 65/152 (42%), Gaps = 4/152 (2%)
Query: 266 FVCSTCHELLVDMIYFWKNEKLYCGRHYCDSEKPRCAGCDELIFSN-EYTQAENQNWHLK 324
F C C + L Y K+ C + + C C + I ++ + +N+ WH
Sbjct: 5 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
Query: 325 HFCCFDCDSILAGEIYVMVNDKPVCKPCYVKNHAVVCQGCHNAIDPEVQRVTYNNFSWHA 384
F C C LA E +V ++K +C C + + C+GC AI Q V Y WH
Sbjct: 65 CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWH- 123
Query: 385 STECFLCSCCSKCLIGQKFMPVEGMVFCSVEC 416
+CF CS C + + F P +G F V C
Sbjct: 124 -KDCFTCSNCKQVIGTGSFFP-KGEDFYCVTC 153
Score = 55.8 bits (133), Expect = 7e-08
Identities = 31/102 (30%), Positives = 44/102 (43%), Gaps = 4/102 (3%)
Query: 258 DKLWHPACFVCSTCHELLVDMIYFWKNEKLYCGRHYCDSEKPRCAGCDELIF----SNEY 313
D+ WH CFVC TC + L + ++ YC Y + +CAGC I +
Sbjct: 178 DQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSV 237
Query: 314 TQAENQNWHLKHFCCFDCDSILAGEIYVMVNDKPVCKPCYVK 355
E Q+WH F C C LA + +V ++ C C K
Sbjct: 238 VAYEGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAKK 279
>gi|228480211 four and a half LIM domains 1 isoform 1 [Homo sapiens]
Length = 323
Score = 93.6 bits (231), Expect = 3e-19
Identities = 47/162 (29%), Positives = 77/162 (47%), Gaps = 6/162 (3%)
Query: 258 DKLWHPACFVCSTCHELLVDMIYFWKNEKLYCGRHYCDSEKPRCAGC-DELIFSNEYTQA 316
++ WH CF C+ C L + + K+ K+ C + + P+C GC ++ ++ +
Sbjct: 58 NRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEY 117
Query: 317 ENQNWHLKHFCCFDCDSILAGEIYVMVNDKPVCKPCYVKNHAVVCQGCHNAIDPEVQRVT 376
+ WH F C +C ++ + + C C+ A C C+ AI +T
Sbjct: 118 KGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITS--GGIT 175
Query: 377 YNNFSWHASTECFLCSCCSKCLIGQKFMPVEGMVFCSVECKK 418
Y + WHA +CF+C CSK L GQ+F VE +C V+C K
Sbjct: 176 YQDQPWHA--DCFVCVTCSKKLAGQRFTAVEDQYYC-VDCYK 214
Score = 74.7 bits (182), Expect = 1e-13
Identities = 40/120 (33%), Positives = 56/120 (46%), Gaps = 3/120 (2%)
Query: 260 LWHPACFVCSTCHELLVDMIYFWKNEKLYCGRHYCDSEKPRCAGCDELIFSNEYTQAENQ 319
+WH CF CS C +++ +F K E YC + C C++ I S T ++Q
Sbjct: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITY-QDQ 179
Query: 320 NWHLKHFCCFDCDSILAGEIYVMVNDKPVCKPCYVKNHAVVCQGCHNAIDPE--VQRVTY 377
WH F C C LAG+ + V D+ C CY A C GC N I + V RV++
Sbjct: 180 PWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGKRTVSRVSH 239
Score = 64.3 bits (155), Expect = 2e-10
Identities = 44/152 (28%), Positives = 65/152 (42%), Gaps = 4/152 (2%)
Query: 266 FVCSTCHELLVDMIYFWKNEKLYCGRHYCDSEKPRCAGCDELIFSN-EYTQAENQNWHLK 324
F C C + L Y K+ C + + C C + I ++ + +N+ WH
Sbjct: 5 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
Query: 325 HFCCFDCDSILAGEIYVMVNDKPVCKPCYVKNHAVVCQGCHNAIDPEVQRVTYNNFSWHA 384
F C C LA E +V ++K +C C + + C+GC AI Q V Y WH
Sbjct: 65 CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWH- 123
Query: 385 STECFLCSCCSKCLIGQKFMPVEGMVFCSVEC 416
+CF CS C + + F P +G F V C
Sbjct: 124 -KDCFTCSNCKQVIGTGSFFP-KGEDFYCVTC 153
Score = 40.4 bits (93), Expect = 0.003
Identities = 17/47 (36%), Positives = 24/47 (51%)
Query: 258 DKLWHPACFVCSTCHELLVDMIYFWKNEKLYCGRHYCDSEKPRCAGC 304
D+ WH CFVC TC + L + ++ YC Y + +CAGC
Sbjct: 178 DQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGC 224
>gi|228480207 four and a half LIM domains 1 isoform 2 [Homo sapiens]
Length = 280
Score = 93.6 bits (231), Expect = 3e-19
Identities = 47/162 (29%), Positives = 77/162 (47%), Gaps = 6/162 (3%)
Query: 258 DKLWHPACFVCSTCHELLVDMIYFWKNEKLYCGRHYCDSEKPRCAGC-DELIFSNEYTQA 316
++ WH CF C+ C L + + K+ K+ C + + P+C GC ++ ++ +
Sbjct: 58 NRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEY 117
Query: 317 ENQNWHLKHFCCFDCDSILAGEIYVMVNDKPVCKPCYVKNHAVVCQGCHNAIDPEVQRVT 376
+ WH F C +C ++ + + C C+ A C C+ AI +T
Sbjct: 118 KGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITS--GGIT 175
Query: 377 YNNFSWHASTECFLCSCCSKCLIGQKFMPVEGMVFCSVECKK 418
Y + WHA +CF+C CSK L GQ+F VE +C V+C K
Sbjct: 176 YQDQPWHA--DCFVCVTCSKKLAGQRFTAVEDQYYC-VDCYK 214
Score = 92.0 bits (227), Expect = 9e-19
Identities = 53/164 (32%), Positives = 74/164 (45%), Gaps = 7/164 (4%)
Query: 260 LWHPACFVCSTCHELLVDMIYFWKNEKLYCGRHYCDSEKPRCAGCDELIFSNEYTQAENQ 319
+WH CF CS C +++ +F K E YC + C C++ I S T ++Q
Sbjct: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITY-QDQ 179
Query: 320 NWHLKHFCCFDCDSILAGEIYVMVNDKPVCKPCYVKNHAVVCQGCHNAI---DPEVQRVT 376
WH F C C LAG+ + V D+ C CY A C GC N I V
Sbjct: 180 PWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVVA 239
Query: 377 YNNFSWHASTECFLCSCCSKCLIGQKFMPVEGMVFCSVECKKRM 420
Y SWH CF C CS L ++F+ + V+C +C K++
Sbjct: 240 YEGQSWH--DYCFHCKKCSVNLANKRFVFHQEQVYCP-DCAKKL 280
Score = 64.3 bits (155), Expect = 2e-10
Identities = 44/152 (28%), Positives = 65/152 (42%), Gaps = 4/152 (2%)
Query: 266 FVCSTCHELLVDMIYFWKNEKLYCGRHYCDSEKPRCAGCDELIFSN-EYTQAENQNWHLK 324
F C C + L Y K+ C + + C C + I ++ + +N+ WH
Sbjct: 5 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
Query: 325 HFCCFDCDSILAGEIYVMVNDKPVCKPCYVKNHAVVCQGCHNAIDPEVQRVTYNNFSWHA 384
F C C LA E +V ++K +C C + + C+GC AI Q V Y WH
Sbjct: 65 CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWH- 123
Query: 385 STECFLCSCCSKCLIGQKFMPVEGMVFCSVEC 416
+CF CS C + + F P +G F V C
Sbjct: 124 -KDCFTCSNCKQVIGTGSFFP-KGEDFYCVTC 153
Score = 55.8 bits (133), Expect = 7e-08
Identities = 31/102 (30%), Positives = 44/102 (43%), Gaps = 4/102 (3%)
Query: 258 DKLWHPACFVCSTCHELLVDMIYFWKNEKLYCGRHYCDSEKPRCAGCDELIF----SNEY 313
D+ WH CFVC TC + L + ++ YC Y + +CAGC I +
Sbjct: 178 DQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSV 237
Query: 314 TQAENQNWHLKHFCCFDCDSILAGEIYVMVNDKPVCKPCYVK 355
E Q+WH F C C LA + +V ++ C C K
Sbjct: 238 VAYEGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAKK 279
>gi|228480209 four and a half LIM domains 1 isoform 3 [Homo sapiens]
Length = 309
Score = 93.6 bits (231), Expect = 3e-19
Identities = 47/162 (29%), Positives = 77/162 (47%), Gaps = 6/162 (3%)
Query: 258 DKLWHPACFVCSTCHELLVDMIYFWKNEKLYCGRHYCDSEKPRCAGC-DELIFSNEYTQA 316
++ WH CF C+ C L + + K+ K+ C + + P+C GC ++ ++ +
Sbjct: 87 NRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEY 146
Query: 317 ENQNWHLKHFCCFDCDSILAGEIYVMVNDKPVCKPCYVKNHAVVCQGCHNAIDPEVQRVT 376
+ WH F C +C ++ + + C C+ A C C+ AI +T
Sbjct: 147 KGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITS--GGIT 204
Query: 377 YNNFSWHASTECFLCSCCSKCLIGQKFMPVEGMVFCSVECKK 418
Y + WHA +CF+C CSK L GQ+F VE +C V+C K
Sbjct: 205 YQDQPWHA--DCFVCVTCSKKLAGQRFTAVEDQYYC-VDCYK 243
Score = 92.0 bits (227), Expect = 9e-19
Identities = 53/164 (32%), Positives = 74/164 (45%), Gaps = 7/164 (4%)
Query: 260 LWHPACFVCSTCHELLVDMIYFWKNEKLYCGRHYCDSEKPRCAGCDELIFSNEYTQAENQ 319
+WH CF CS C +++ +F K E YC + C C++ I S T ++Q
Sbjct: 150 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITY-QDQ 208
Query: 320 NWHLKHFCCFDCDSILAGEIYVMVNDKPVCKPCYVKNHAVVCQGCHNAI---DPEVQRVT 376
WH F C C LAG+ + V D+ C CY A C GC N I V
Sbjct: 209 PWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVVA 268
Query: 377 YNNFSWHASTECFLCSCCSKCLIGQKFMPVEGMVFCSVECKKRM 420
Y SWH CF C CS L ++F+ + V+C +C K++
Sbjct: 269 YEGQSWH--DYCFHCKKCSVNLANKRFVFHQEQVYCP-DCAKKL 309
Score = 64.3 bits (155), Expect = 2e-10
Identities = 44/152 (28%), Positives = 65/152 (42%), Gaps = 4/152 (2%)
Query: 266 FVCSTCHELLVDMIYFWKNEKLYCGRHYCDSEKPRCAGCDELIFSN-EYTQAENQNWHLK 324
F C C + L Y K+ C + + C C + I ++ + +N+ WH
Sbjct: 34 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 93
Query: 325 HFCCFDCDSILAGEIYVMVNDKPVCKPCYVKNHAVVCQGCHNAIDPEVQRVTYNNFSWHA 384
F C C LA E +V ++K +C C + + C+GC AI Q V Y WH
Sbjct: 94 CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWH- 152
Query: 385 STECFLCSCCSKCLIGQKFMPVEGMVFCSVEC 416
+CF CS C + + F P +G F V C
Sbjct: 153 -KDCFTCSNCKQVIGTGSFFP-KGEDFYCVTC 182
Score = 55.8 bits (133), Expect = 7e-08
Identities = 31/102 (30%), Positives = 44/102 (43%), Gaps = 4/102 (3%)
Query: 258 DKLWHPACFVCSTCHELLVDMIYFWKNEKLYCGRHYCDSEKPRCAGCDELIF----SNEY 313
D+ WH CFVC TC + L + ++ YC Y + +CAGC I +
Sbjct: 207 DQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSV 266
Query: 314 TQAENQNWHLKHFCCFDCDSILAGEIYVMVNDKPVCKPCYVK 355
E Q+WH F C C LA + +V ++ C C K
Sbjct: 267 VAYEGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAKK 308
>gi|228480205 four and a half LIM domains 1 isoform 5 [Homo sapiens]
Length = 296
Score = 93.6 bits (231), Expect = 3e-19
Identities = 47/162 (29%), Positives = 77/162 (47%), Gaps = 6/162 (3%)
Query: 258 DKLWHPACFVCSTCHELLVDMIYFWKNEKLYCGRHYCDSEKPRCAGC-DELIFSNEYTQA 316
++ WH CF C+ C L + + K+ K+ C + + P+C GC ++ ++ +
Sbjct: 74 NRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEY 133
Query: 317 ENQNWHLKHFCCFDCDSILAGEIYVMVNDKPVCKPCYVKNHAVVCQGCHNAIDPEVQRVT 376
+ WH F C +C ++ + + C C+ A C C+ AI +T
Sbjct: 134 KGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITS--GGIT 191
Query: 377 YNNFSWHASTECFLCSCCSKCLIGQKFMPVEGMVFCSVECKK 418
Y + WHA +CF+C CSK L GQ+F VE +C V+C K
Sbjct: 192 YQDQPWHA--DCFVCVTCSKKLAGQRFTAVEDQYYC-VDCYK 230
Score = 92.0 bits (227), Expect = 9e-19
Identities = 53/164 (32%), Positives = 74/164 (45%), Gaps = 7/164 (4%)
Query: 260 LWHPACFVCSTCHELLVDMIYFWKNEKLYCGRHYCDSEKPRCAGCDELIFSNEYTQAENQ 319
+WH CF CS C +++ +F K E YC + C C++ I S T ++Q
Sbjct: 137 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITY-QDQ 195
Query: 320 NWHLKHFCCFDCDSILAGEIYVMVNDKPVCKPCYVKNHAVVCQGCHNAI---DPEVQRVT 376
WH F C C LAG+ + V D+ C CY A C GC N I V
Sbjct: 196 PWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVVA 255
Query: 377 YNNFSWHASTECFLCSCCSKCLIGQKFMPVEGMVFCSVECKKRM 420
Y SWH CF C CS L ++F+ + V+C +C K++
Sbjct: 256 YEGQSWH--DYCFHCKKCSVNLANKRFVFHQEQVYCP-DCAKKL 296
Score = 64.3 bits (155), Expect = 2e-10
Identities = 44/152 (28%), Positives = 65/152 (42%), Gaps = 4/152 (2%)
Query: 266 FVCSTCHELLVDMIYFWKNEKLYCGRHYCDSEKPRCAGCDELIFSN-EYTQAENQNWHLK 324
F C C + L Y K+ C + + C C + I ++ + +N+ WH
Sbjct: 21 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 80
Query: 325 HFCCFDCDSILAGEIYVMVNDKPVCKPCYVKNHAVVCQGCHNAIDPEVQRVTYNNFSWHA 384
F C C LA E +V ++K +C C + + C+GC AI Q V Y WH
Sbjct: 81 CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWH- 139
Query: 385 STECFLCSCCSKCLIGQKFMPVEGMVFCSVEC 416
+CF CS C + + F P +G F V C
Sbjct: 140 -KDCFTCSNCKQVIGTGSFFP-KGEDFYCVTC 169
Score = 55.8 bits (133), Expect = 7e-08
Identities = 31/102 (30%), Positives = 44/102 (43%), Gaps = 4/102 (3%)
Query: 258 DKLWHPACFVCSTCHELLVDMIYFWKNEKLYCGRHYCDSEKPRCAGCDELIF----SNEY 313
D+ WH CFVC TC + L + ++ YC Y + +CAGC I +
Sbjct: 194 DQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSV 253
Query: 314 TQAENQNWHLKHFCCFDCDSILAGEIYVMVNDKPVCKPCYVK 355
E Q+WH F C C LA + +V ++ C C K
Sbjct: 254 VAYEGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAKK 295
>gi|21361122 four and a half LIM domains 1 isoform 2 [Homo sapiens]
Length = 280
Score = 93.6 bits (231), Expect = 3e-19
Identities = 47/162 (29%), Positives = 77/162 (47%), Gaps = 6/162 (3%)
Query: 258 DKLWHPACFVCSTCHELLVDMIYFWKNEKLYCGRHYCDSEKPRCAGC-DELIFSNEYTQA 316
++ WH CF C+ C L + + K+ K+ C + + P+C GC ++ ++ +
Sbjct: 58 NRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEY 117
Query: 317 ENQNWHLKHFCCFDCDSILAGEIYVMVNDKPVCKPCYVKNHAVVCQGCHNAIDPEVQRVT 376
+ WH F C +C ++ + + C C+ A C C+ AI +T
Sbjct: 118 KGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITS--GGIT 175
Query: 377 YNNFSWHASTECFLCSCCSKCLIGQKFMPVEGMVFCSVECKK 418
Y + WHA +CF+C CSK L GQ+F VE +C V+C K
Sbjct: 176 YQDQPWHA--DCFVCVTCSKKLAGQRFTAVEDQYYC-VDCYK 214
Score = 92.0 bits (227), Expect = 9e-19
Identities = 53/164 (32%), Positives = 74/164 (45%), Gaps = 7/164 (4%)
Query: 260 LWHPACFVCSTCHELLVDMIYFWKNEKLYCGRHYCDSEKPRCAGCDELIFSNEYTQAENQ 319
+WH CF CS C +++ +F K E YC + C C++ I S T ++Q
Sbjct: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITY-QDQ 179
Query: 320 NWHLKHFCCFDCDSILAGEIYVMVNDKPVCKPCYVKNHAVVCQGCHNAI---DPEVQRVT 376
WH F C C LAG+ + V D+ C CY A C GC N I V
Sbjct: 180 PWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVVA 239
Query: 377 YNNFSWHASTECFLCSCCSKCLIGQKFMPVEGMVFCSVECKKRM 420
Y SWH CF C CS L ++F+ + V+C +C K++
Sbjct: 240 YEGQSWH--DYCFHCKKCSVNLANKRFVFHQEQVYCP-DCAKKL 280
Score = 64.3 bits (155), Expect = 2e-10
Identities = 44/152 (28%), Positives = 65/152 (42%), Gaps = 4/152 (2%)
Query: 266 FVCSTCHELLVDMIYFWKNEKLYCGRHYCDSEKPRCAGCDELIFSN-EYTQAENQNWHLK 324
F C C + L Y K+ C + + C C + I ++ + +N+ WH
Sbjct: 5 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
Query: 325 HFCCFDCDSILAGEIYVMVNDKPVCKPCYVKNHAVVCQGCHNAIDPEVQRVTYNNFSWHA 384
F C C LA E +V ++K +C C + + C+GC AI Q V Y WH
Sbjct: 65 CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWH- 123
Query: 385 STECFLCSCCSKCLIGQKFMPVEGMVFCSVEC 416
+CF CS C + + F P +G F V C
Sbjct: 124 -KDCFTCSNCKQVIGTGSFFP-KGEDFYCVTC 153
Score = 55.8 bits (133), Expect = 7e-08
Identities = 31/102 (30%), Positives = 44/102 (43%), Gaps = 4/102 (3%)
Query: 258 DKLWHPACFVCSTCHELLVDMIYFWKNEKLYCGRHYCDSEKPRCAGCDELIF----SNEY 313
D+ WH CFVC TC + L + ++ YC Y + +CAGC I +
Sbjct: 178 DQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSV 237
Query: 314 TQAENQNWHLKHFCCFDCDSILAGEIYVMVNDKPVCKPCYVK 355
E Q+WH F C C LA + +V ++ C C K
Sbjct: 238 VAYEGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAKK 279
>gi|170932518 paxillin isoform 3 [Homo sapiens]
Length = 424
Score = 85.9 bits (211), Expect = 6e-17
Identities = 49/161 (30%), Positives = 72/161 (44%), Gaps = 5/161 (3%)
Query: 259 KLWHPACFVCSTCHELLVDMIYFWKNEKLYCGRHYCDSEKPRCAGCDELIFSNEYTQAEN 318
K WHP FVC+ C E + +F ++ + YC + Y + PRC C+ I T A +
Sbjct: 208 KTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYCNGPILDKVVT-ALD 266
Query: 319 QNWHLKHFCCFDCDSILAGEIYVMVNDKPVCKPCYVKNHAVVCQGCHNAIDPEVQRVTYN 378
+ WH +HF C C + E + + K C+ Y A C GC AI ++
Sbjct: 267 RTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKCGGCARAILENY--ISAL 324
Query: 379 NFSWHASTECFLCSCCSKCLIGQKFMPVEGMVFCSVECKKR 419
N WH ECF+C C + F +G +C V +R
Sbjct: 325 NTLWH--PECFVCRECFTPFVNGSFFEHDGQPYCEVHYHER 363
Score = 75.5 bits (184), Expect = 9e-14
Identities = 47/177 (26%), Positives = 66/177 (37%), Gaps = 11/177 (6%)
Query: 236 CYCCKLSMKEGDPAIYAERAGYDKLWHPACFVCSTCHELLVDMIYFWKNEKLYCGRHYCD 295
CY C P + D+ WHP F C+ C + K+ K YC + Y D
Sbjct: 250 CYYCN------GPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFD 303
Query: 296 SEKPRCAGCDELIFSNEYTQAENQNWHLKHFCCFDCDSILAGEIYVMVNDKPVCKPCYVK 355
P+C GC I N Y A N WH + F C +C + + + +P C+ Y +
Sbjct: 304 MFAPKCGGCARAILEN-YISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHE 362
Query: 356 NHAVVCQGCHNAIDPEVQRVTYNNFSWHASTECFLCSCCSKCLIGQKFMPVEGMVFC 412
+C GC I F E F+C+ C K L F +C
Sbjct: 363 RRGSLCSGCQKPITGRCITAMAKKF----HPEHFVCAFCLKQLNKGTFKEQNDKPYC 415
Score = 67.4 bits (163), Expect = 2e-11
Identities = 34/96 (35%), Positives = 48/96 (50%), Gaps = 1/96 (1%)
Query: 260 LWHPACFVCSTCHELLVDMIYFWKNEKLYCGRHYCDSEKPRCAGCDELIFSNEYTQAENQ 319
LWHP CFVC C V+ +F + + YC HY + C+GC + I T A +
Sbjct: 327 LWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQKPITGRCIT-AMAK 385
Query: 320 NWHLKHFCCFDCDSILAGEIYVMVNDKPVCKPCYVK 355
+H +HF C C L + NDKP C+ C++K
Sbjct: 386 KFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLK 421
Score = 45.4 bits (106), Expect = 9e-05
Identities = 28/112 (25%), Positives = 47/112 (41%), Gaps = 5/112 (4%)
Query: 301 CAGCDELIFSNEYTQAENQNWHLKHFCCFDCDSILAGEIYVMVNDKPVCKPCYVKNHAVV 360
C C + I + + A + WH +HF C C + + + +P C+ Y +
Sbjct: 191 CGACKKPI-AGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPR 249
Query: 361 CQGCHNAIDPEVQRVTYNNFSWHASTECFLCSCCSKCLIGQKFMPVEGMVFC 412
C C+ I +V VT + +WH E F C+ C + F +G +C
Sbjct: 250 CYYCNGPILDKV--VTALDRTWH--PEHFFCAQCGAFFGPEGFHEKDGKAYC 297
>gi|170932516 paxillin isoform 2 [Homo sapiens]
Length = 557
Score = 85.9 bits (211), Expect = 6e-17
Identities = 49/161 (30%), Positives = 72/161 (44%), Gaps = 5/161 (3%)
Query: 259 KLWHPACFVCSTCHELLVDMIYFWKNEKLYCGRHYCDSEKPRCAGCDELIFSNEYTQAEN 318
K WHP FVC+ C E + +F ++ + YC + Y + PRC C+ I T A +
Sbjct: 341 KTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYCNGPILDKVVT-ALD 399
Query: 319 QNWHLKHFCCFDCDSILAGEIYVMVNDKPVCKPCYVKNHAVVCQGCHNAIDPEVQRVTYN 378
+ WH +HF C C + E + + K C+ Y A C GC AI ++
Sbjct: 400 RTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKCGGCARAILENY--ISAL 457
Query: 379 NFSWHASTECFLCSCCSKCLIGQKFMPVEGMVFCSVECKKR 419
N WH ECF+C C + F +G +C V +R
Sbjct: 458 NTLWH--PECFVCRECFTPFVNGSFFEHDGQPYCEVHYHER 496
Score = 75.5 bits (184), Expect = 9e-14
Identities = 47/177 (26%), Positives = 66/177 (37%), Gaps = 11/177 (6%)
Query: 236 CYCCKLSMKEGDPAIYAERAGYDKLWHPACFVCSTCHELLVDMIYFWKNEKLYCGRHYCD 295
CY C P + D+ WHP F C+ C + K+ K YC + Y D
Sbjct: 383 CYYCN------GPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFD 436
Query: 296 SEKPRCAGCDELIFSNEYTQAENQNWHLKHFCCFDCDSILAGEIYVMVNDKPVCKPCYVK 355
P+C GC I N Y A N WH + F C +C + + + +P C+ Y +
Sbjct: 437 MFAPKCGGCARAILEN-YISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHE 495
Query: 356 NHAVVCQGCHNAIDPEVQRVTYNNFSWHASTECFLCSCCSKCLIGQKFMPVEGMVFC 412
+C GC I F E F+C+ C K L F +C
Sbjct: 496 RRGSLCSGCQKPITGRCITAMAKKF----HPEHFVCAFCLKQLNKGTFKEQNDKPYC 548
Score = 67.4 bits (163), Expect = 2e-11
Identities = 34/96 (35%), Positives = 48/96 (50%), Gaps = 1/96 (1%)
Query: 260 LWHPACFVCSTCHELLVDMIYFWKNEKLYCGRHYCDSEKPRCAGCDELIFSNEYTQAENQ 319
LWHP CFVC C V+ +F + + YC HY + C+GC + I T A +
Sbjct: 460 LWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQKPITGRCIT-AMAK 518
Query: 320 NWHLKHFCCFDCDSILAGEIYVMVNDKPVCKPCYVK 355
+H +HF C C L + NDKP C+ C++K
Sbjct: 519 KFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLK 554
Score = 45.4 bits (106), Expect = 9e-05
Identities = 28/112 (25%), Positives = 47/112 (41%), Gaps = 5/112 (4%)
Query: 301 CAGCDELIFSNEYTQAENQNWHLKHFCCFDCDSILAGEIYVMVNDKPVCKPCYVKNHAVV 360
C C + I + + A + WH +HF C C + + + +P C+ Y +
Sbjct: 324 CGACKKPI-AGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPR 382
Query: 361 CQGCHNAIDPEVQRVTYNNFSWHASTECFLCSCCSKCLIGQKFMPVEGMVFC 412
C C+ I +V VT + +WH E F C+ C + F +G +C
Sbjct: 383 CYYCNGPILDKV--VTALDRTWH--PEHFFCAQCGAFFGPEGFHEKDGKAYC 430
>gi|170932514 paxillin isoform 1 [Homo sapiens]
Length = 591
Score = 85.9 bits (211), Expect = 6e-17
Identities = 49/161 (30%), Positives = 72/161 (44%), Gaps = 5/161 (3%)
Query: 259 KLWHPACFVCSTCHELLVDMIYFWKNEKLYCGRHYCDSEKPRCAGCDELIFSNEYTQAEN 318
K WHP FVC+ C E + +F ++ + YC + Y + PRC C+ I T A +
Sbjct: 375 KTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYCNGPILDKVVT-ALD 433
Query: 319 QNWHLKHFCCFDCDSILAGEIYVMVNDKPVCKPCYVKNHAVVCQGCHNAIDPEVQRVTYN 378
+ WH +HF C C + E + + K C+ Y A C GC AI ++
Sbjct: 434 RTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKCGGCARAILENY--ISAL 491
Query: 379 NFSWHASTECFLCSCCSKCLIGQKFMPVEGMVFCSVECKKR 419
N WH ECF+C C + F +G +C V +R
Sbjct: 492 NTLWH--PECFVCRECFTPFVNGSFFEHDGQPYCEVHYHER 530
Score = 75.5 bits (184), Expect = 9e-14
Identities = 47/177 (26%), Positives = 66/177 (37%), Gaps = 11/177 (6%)
Query: 236 CYCCKLSMKEGDPAIYAERAGYDKLWHPACFVCSTCHELLVDMIYFWKNEKLYCGRHYCD 295
CY C P + D+ WHP F C+ C + K+ K YC + Y D
Sbjct: 417 CYYCN------GPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFD 470
Query: 296 SEKPRCAGCDELIFSNEYTQAENQNWHLKHFCCFDCDSILAGEIYVMVNDKPVCKPCYVK 355
P+C GC I N Y A N WH + F C +C + + + +P C+ Y +
Sbjct: 471 MFAPKCGGCARAILEN-YISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHE 529
Query: 356 NHAVVCQGCHNAIDPEVQRVTYNNFSWHASTECFLCSCCSKCLIGQKFMPVEGMVFC 412
+C GC I F E F+C+ C K L F +C
Sbjct: 530 RRGSLCSGCQKPITGRCITAMAKKF----HPEHFVCAFCLKQLNKGTFKEQNDKPYC 582
Score = 67.4 bits (163), Expect = 2e-11
Identities = 34/96 (35%), Positives = 48/96 (50%), Gaps = 1/96 (1%)
Query: 260 LWHPACFVCSTCHELLVDMIYFWKNEKLYCGRHYCDSEKPRCAGCDELIFSNEYTQAENQ 319
LWHP CFVC C V+ +F + + YC HY + C+GC + I T A +
Sbjct: 494 LWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQKPITGRCIT-AMAK 552
Query: 320 NWHLKHFCCFDCDSILAGEIYVMVNDKPVCKPCYVK 355
+H +HF C C L + NDKP C+ C++K
Sbjct: 553 KFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLK 588
Score = 45.4 bits (106), Expect = 9e-05
Identities = 28/112 (25%), Positives = 47/112 (41%), Gaps = 5/112 (4%)
Query: 301 CAGCDELIFSNEYTQAENQNWHLKHFCCFDCDSILAGEIYVMVNDKPVCKPCYVKNHAVV 360
C C + I + + A + WH +HF C C + + + +P C+ Y +
Sbjct: 358 CGACKKPI-AGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPR 416
Query: 361 CQGCHNAIDPEVQRVTYNNFSWHASTECFLCSCCSKCLIGQKFMPVEGMVFC 412
C C+ I +V VT + +WH E F C+ C + F +G +C
Sbjct: 417 CYYCNGPILDKV--VTALDRTWH--PEHFFCAQCGAFFGPEGFHEKDGKAYC 464
>gi|221316659 leupaxin isoform 1 [Homo sapiens]
Length = 391
Score = 85.9 bits (211), Expect = 6e-17
Identities = 47/159 (29%), Positives = 69/159 (43%), Gaps = 5/159 (3%)
Query: 261 WHPACFVCSTCHELLVDMIYFWKNEKLYCGRHYCDSEKPRCAGCDELIFSNEYTQAENQN 320
WHP FVC+ C E + +F ++ YC Y PRCA C I T A NQ
Sbjct: 176 WHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSPRCAYCAAPILDKVLT-AMNQT 234
Query: 321 WHLKHFCCFDCDSILAGEIYVMVNDKPVCKPCYVKNHAVVCQGCHNAIDPEVQRVTYNNF 380
WH +HF C C + E + + KP C+ ++ + C GC+ + ++ +
Sbjct: 235 WHPEHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFSPKCGGCNRPVLENY--LSAMDT 292
Query: 381 SWHASTECFLCSCCSKCLIGQKFMPVEGMVFCSVECKKR 419
WH ECF+C C F ++G FC + R
Sbjct: 293 VWH--PECFVCGDCFTSFSTGSFFELDGRPFCELHYHHR 329
Score = 71.6 bits (174), Expect = 1e-12
Identities = 40/155 (25%), Positives = 68/155 (43%), Gaps = 5/155 (3%)
Query: 258 DKLWHPACFVCSTCHELLVDMIYFWKNEKLYCGRHYCDSEKPRCAGCDELIFSNEYTQAE 317
++ WHP F CS C E+ + K++K YC + + P+C GC+ + N Y A
Sbjct: 232 NQTWHPEHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFSPKCGGCNRPVLEN-YLSAM 290
Query: 318 NQNWHLKHFCCFDCDSILAGEIYVMVNDKPVCKPCYVKNHAVVCQGCHNAIDPEVQRVTY 377
+ WH + F C DC + + + ++ +P C+ Y +C GC I ++
Sbjct: 291 DTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGTLCHGCGQPITGRC--ISA 348
Query: 378 NNFSWHASTECFLCSCCSKCLIGQKFMPVEGMVFC 412
+ +H E F+C+ C L F +C
Sbjct: 349 MGYKFH--PEHFVCAFCLTQLSKGIFREQNDKTYC 381
Score = 64.7 bits (156), Expect = 2e-10
Identities = 33/108 (30%), Positives = 49/108 (45%), Gaps = 1/108 (0%)
Query: 248 PAIYAERAGYDKLWHPACFVCSTCHELLVDMIYFWKNEKLYCGRHYCDSEKPRCAGCDEL 307
P + + D +WHP CFVC C +F + + +C HY C GC +
Sbjct: 281 PVLENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGTLCHGCGQP 340
Query: 308 IFSNEYTQAENQNWHLKHFCCFDCDSILAGEIYVMVNDKPVCKPCYVK 355
I + A +H +HF C C + L+ I+ NDK C+PC+ K
Sbjct: 341 I-TGRCISAMGYKFHPEHFVCAFCLTQLSKGIFREQNDKTYCQPCFNK 387
Score = 42.7 bits (99), Expect = 6e-04
Identities = 30/115 (26%), Positives = 47/115 (40%), Gaps = 5/115 (4%)
Query: 298 KPRCAGCDELIFSNEYTQAENQNWHLKHFCCFDCDSILAGEIYVMVNDKPVCKPCYVKNH 357
K CA C + I + + A Q+WH +HF C C + + + C Y +
Sbjct: 154 KGHCASCQKPI-AGKVIHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLF 212
Query: 358 AVVCQGCHNAIDPEVQRVTYNNFSWHASTECFLCSCCSKCLIGQKFMPVEGMVFC 412
+ C C I +V +T N +WH E F CS C + + F + +C
Sbjct: 213 SPRCAYCAAPILDKV--LTAMNQTWH--PEHFFCSHCGEVFGAEGFHEKDKKPYC 263
>gi|4758670 leupaxin isoform 2 [Homo sapiens]
Length = 386
Score = 85.9 bits (211), Expect = 6e-17
Identities = 47/159 (29%), Positives = 69/159 (43%), Gaps = 5/159 (3%)
Query: 261 WHPACFVCSTCHELLVDMIYFWKNEKLYCGRHYCDSEKPRCAGCDELIFSNEYTQAENQN 320
WHP FVC+ C E + +F ++ YC Y PRCA C I T A NQ
Sbjct: 171 WHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSPRCAYCAAPILDKVLT-AMNQT 229
Query: 321 WHLKHFCCFDCDSILAGEIYVMVNDKPVCKPCYVKNHAVVCQGCHNAIDPEVQRVTYNNF 380
WH +HF C C + E + + KP C+ ++ + C GC+ + ++ +
Sbjct: 230 WHPEHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFSPKCGGCNRPVLENY--LSAMDT 287
Query: 381 SWHASTECFLCSCCSKCLIGQKFMPVEGMVFCSVECKKR 419
WH ECF+C C F ++G FC + R
Sbjct: 288 VWH--PECFVCGDCFTSFSTGSFFELDGRPFCELHYHHR 324
Score = 71.6 bits (174), Expect = 1e-12
Identities = 40/155 (25%), Positives = 68/155 (43%), Gaps = 5/155 (3%)
Query: 258 DKLWHPACFVCSTCHELLVDMIYFWKNEKLYCGRHYCDSEKPRCAGCDELIFSNEYTQAE 317
++ WHP F CS C E+ + K++K YC + + P+C GC+ + N Y A
Sbjct: 227 NQTWHPEHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFSPKCGGCNRPVLEN-YLSAM 285
Query: 318 NQNWHLKHFCCFDCDSILAGEIYVMVNDKPVCKPCYVKNHAVVCQGCHNAIDPEVQRVTY 377
+ WH + F C DC + + + ++ +P C+ Y +C GC I ++
Sbjct: 286 DTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGTLCHGCGQPITGRC--ISA 343
Query: 378 NNFSWHASTECFLCSCCSKCLIGQKFMPVEGMVFC 412
+ +H E F+C+ C L F +C
Sbjct: 344 MGYKFH--PEHFVCAFCLTQLSKGIFREQNDKTYC 376
Score = 64.7 bits (156), Expect = 2e-10
Identities = 33/108 (30%), Positives = 49/108 (45%), Gaps = 1/108 (0%)
Query: 248 PAIYAERAGYDKLWHPACFVCSTCHELLVDMIYFWKNEKLYCGRHYCDSEKPRCAGCDEL 307
P + + D +WHP CFVC C +F + + +C HY C GC +
Sbjct: 276 PVLENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGTLCHGCGQP 335
Query: 308 IFSNEYTQAENQNWHLKHFCCFDCDSILAGEIYVMVNDKPVCKPCYVK 355
I + A +H +HF C C + L+ I+ NDK C+PC+ K
Sbjct: 336 I-TGRCISAMGYKFHPEHFVCAFCLTQLSKGIFREQNDKTYCQPCFNK 382
Score = 42.7 bits (99), Expect = 6e-04
Identities = 30/115 (26%), Positives = 47/115 (40%), Gaps = 5/115 (4%)
Query: 298 KPRCAGCDELIFSNEYTQAENQNWHLKHFCCFDCDSILAGEIYVMVNDKPVCKPCYVKNH 357
K CA C + I + + A Q+WH +HF C C + + + C Y +
Sbjct: 149 KGHCASCQKPI-AGKVIHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLF 207
Query: 358 AVVCQGCHNAIDPEVQRVTYNNFSWHASTECFLCSCCSKCLIGQKFMPVEGMVFC 412
+ C C I +V +T N +WH E F CS C + + F + +C
Sbjct: 208 SPRCAYCAAPILDKV--LTAMNQTWH--PEHFFCSHCGEVFGAEGFHEKDKKPYC 258
>gi|122056614 LIM domain binding 3 isoform 2 [Homo sapiens]
Length = 617
Score = 84.0 bits (206), Expect = 2e-16
Identities = 43/152 (28%), Positives = 65/152 (42%), Gaps = 3/152 (1%)
Query: 261 WHPACFVCSTCHELLVDMIYFWKNEKLYCGRHYCDSEKPRCAGCDELIFSNEYTQAENQN 320
WHP F C+ C L D+ + + +YC R Y P CA C+ I E A Q
Sbjct: 460 WHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLCAKCNTKIMG-EVMHALRQT 518
Query: 321 WHLKHFCCFDCDSILAGEIYVMVNDKPVCKPCYVKNHAVVCQGCHNAIDPEVQRVTYNNF 380
WH F C C ++ M + +P C+ Y+ + C GC ++ + +
Sbjct: 519 WHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEALGH 578
Query: 381 SWHASTECFLCSCCSKCLIGQKFMPVEGMVFC 412
+WH + CF+C+ C L GQ F + C
Sbjct: 579 TWHDT--CFICAVCHVNLEGQPFYSKKDRPLC 608
Score = 62.8 bits (151), Expect = 6e-10
Identities = 31/114 (27%), Positives = 55/114 (48%), Gaps = 5/114 (4%)
Query: 238 CCKLSMKEGDPAIYAERAGYDKLWHPACFVCSTCHELLVDMIYFWKNEKLYCGRHYCDSE 297
C K + K ++A R + WH CFVC+ C + + ++ ++ + YC + Y +
Sbjct: 500 CAKCNTKIMGEVMHALR----QTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLF 555
Query: 298 KPRCAGCD-ELIFSNEYTQAENQNWHLKHFCCFDCDSILAGEIYVMVNDKPVCK 350
+C GCD + +++ +A WH F C C L G+ + D+P+CK
Sbjct: 556 STKCHGCDFPVEAGDKFIEALGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLCK 609
Score = 60.8 bits (146), Expect = 2e-09
Identities = 35/122 (28%), Positives = 53/122 (43%), Gaps = 5/122 (4%)
Query: 291 RHYCDSEKPRCAGCDELIFSNEYTQAENQNWHLKHFCCFDCDSILAGEIYVMVNDKPVCK 350
R S P C C+ +I + A ++WH + F C C + LA +V + C+
Sbjct: 431 RFPASSRTPLCGHCNNVI-RGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCE 489
Query: 351 PCYVKNHAVVCQGCHNAIDPEVQRVTYNNFSWHASTECFLCSCCSKCLIGQKFMPVEGMV 410
CY + A +C C+ I EV +WH T CF+C+ C K F +G
Sbjct: 490 RCYEQFFAPLCAKCNTKIMGEVMHALRQ--TWH--TTCFVCAACKKPFGNSLFHMEDGEP 545
Query: 411 FC 412
+C
Sbjct: 546 YC 547
Score = 40.8 bits (94), Expect = 0.002
Identities = 18/57 (31%), Positives = 29/57 (50%), Gaps = 4/57 (7%)
Query: 236 CYCCKLSMKEGDPAIYAERAGYDKLWHPACFVCSTCHELLVDMIYFWKNEKLYCGRH 292
C+ C ++ GD I E G+ WH CF+C+ CH L ++ K ++ C +H
Sbjct: 559 CHGCDFPVEAGDKFI--EALGHT--WHDTCFICAVCHVNLEGQPFYSKKDRPLCKKH 611
>gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens]
Length = 727
Score = 84.0 bits (206), Expect = 2e-16
Identities = 43/152 (28%), Positives = 65/152 (42%), Gaps = 3/152 (1%)
Query: 261 WHPACFVCSTCHELLVDMIYFWKNEKLYCGRHYCDSEKPRCAGCDELIFSNEYTQAENQN 320
WHP F C+ C L D+ + + +YC R Y P CA C+ I E A Q
Sbjct: 570 WHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLCAKCNTKIMG-EVMHALRQT 628
Query: 321 WHLKHFCCFDCDSILAGEIYVMVNDKPVCKPCYVKNHAVVCQGCHNAIDPEVQRVTYNNF 380
WH F C C ++ M + +P C+ Y+ + C GC ++ + +
Sbjct: 629 WHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEALGH 688
Query: 381 SWHASTECFLCSCCSKCLIGQKFMPVEGMVFC 412
+WH + CF+C+ C L GQ F + C
Sbjct: 689 TWHDT--CFICAVCHVNLEGQPFYSKKDRPLC 718
Score = 62.8 bits (151), Expect = 6e-10
Identities = 31/114 (27%), Positives = 55/114 (48%), Gaps = 5/114 (4%)
Query: 238 CCKLSMKEGDPAIYAERAGYDKLWHPACFVCSTCHELLVDMIYFWKNEKLYCGRHYCDSE 297
C K + K ++A R + WH CFVC+ C + + ++ ++ + YC + Y +
Sbjct: 610 CAKCNTKIMGEVMHALR----QTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLF 665
Query: 298 KPRCAGCD-ELIFSNEYTQAENQNWHLKHFCCFDCDSILAGEIYVMVNDKPVCK 350
+C GCD + +++ +A WH F C C L G+ + D+P+CK
Sbjct: 666 STKCHGCDFPVEAGDKFIEALGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLCK 719
Score = 60.8 bits (146), Expect = 2e-09
Identities = 35/122 (28%), Positives = 53/122 (43%), Gaps = 5/122 (4%)
Query: 291 RHYCDSEKPRCAGCDELIFSNEYTQAENQNWHLKHFCCFDCDSILAGEIYVMVNDKPVCK 350
R S P C C+ +I + A ++WH + F C C + LA +V + C+
Sbjct: 541 RFPASSRTPLCGHCNNVI-RGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCE 599
Query: 351 PCYVKNHAVVCQGCHNAIDPEVQRVTYNNFSWHASTECFLCSCCSKCLIGQKFMPVEGMV 410
CY + A +C C+ I EV +WH T CF+C+ C K F +G
Sbjct: 600 RCYEQFFAPLCAKCNTKIMGEVMHALRQ--TWH--TTCFVCAACKKPFGNSLFHMEDGEP 655
Query: 411 FC 412
+C
Sbjct: 656 YC 657
Score = 40.8 bits (94), Expect = 0.002
Identities = 18/57 (31%), Positives = 29/57 (50%), Gaps = 4/57 (7%)
Query: 236 CYCCKLSMKEGDPAIYAERAGYDKLWHPACFVCSTCHELLVDMIYFWKNEKLYCGRH 292
C+ C ++ GD I E G+ WH CF+C+ CH L ++ K ++ C +H
Sbjct: 669 CHGCDFPVEAGDKFI--EALGHT--WHDTCFICAVCHVNLEGQPFYSKKDRPLCKKH 721
>gi|54112385 four and a half LIM domains 3 [Homo sapiens]
Length = 280
Score = 84.0 bits (206), Expect = 2e-16
Identities = 47/154 (30%), Positives = 70/154 (45%), Gaps = 5/154 (3%)
Query: 261 WHPACFVCSTCHELLVDMIYFWKNEKLYCGRHYCDSEKPRCAGCDELIFSNEYTQAENQN 320
WH CF+CS C + L + YC Y + PRCA C + + T + Q
Sbjct: 122 WHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFAPRCARCSKTLTQGGVTYRD-QP 180
Query: 321 WHLKHFCCFDCDSILAGEIYVMVNDKPVCKPCYVKNHAVVCQGCHNAID--PEVQRVTYN 378
WH + C C + LAG+ + ++ P C C+ + A C C I + V++
Sbjct: 181 WHRECLVCTGCQTPLAGQQFTSRDEDPYCVACFGELFAPKCSSCKRPIVGLGGGKYVSFE 240
Query: 379 NFSWHASTECFLCSCCSKCLIGQKFMPVEGMVFC 412
+ WH + CF C+ CS L+GQ F+P V C
Sbjct: 241 DRHWHHN--CFSCARCSTSLVGQGFVPDGDQVLC 272
Score = 82.4 bits (202), Expect = 7e-16
Identities = 44/156 (28%), Positives = 65/156 (41%), Gaps = 5/156 (3%)
Query: 258 DKLWHPACFVCSTCHELLVDMIYFWKNEKLYCGRHYCDSEKPRCAGCDELIF-SNEYTQA 316
D+ +H CF C C L D + ++ +L C YC + +C+ C E + + +
Sbjct: 58 DRHFHEGCFRCCRCQRSLADEPFTCQDSELLCNDCYCSAFSSQCSACGETVMPGSRKLEY 117
Query: 317 ENQNWHLKHFCCFDCDSILAGEIYVMVNDKPVCKPCYVKNHAVVCQGCHNAIDPEVQRVT 376
Q WH F C C+ L +V C PCY A C C + VT
Sbjct: 118 GGQTWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFAPRCARCSKTLTQ--GGVT 175
Query: 377 YNNFSWHASTECFLCSCCSKCLIGQKFMPVEGMVFC 412
Y + WH EC +C+ C L GQ+F + +C
Sbjct: 176 YRDQPWH--RECLVCTGCQTPLAGQQFTSRDEDPYC 209
Score = 75.5 bits (184), Expect = 9e-14
Identities = 42/148 (28%), Positives = 68/148 (45%), Gaps = 3/148 (2%)
Query: 266 FVCSTCHELLVDMIYFWKNEKLYCGRHYCDSEKPRCAGCDELI-FSNEYTQAENQNWHLK 324
F C+ C+E L Y + YC Y ++ CA C +LI + E++++H
Sbjct: 5 FDCAKCNESLYGRKYIQTDSGPYCVPCYDNTFANTCAECQQLIGHDSRELFYEDRHFHEG 64
Query: 325 HFCCFDCDSILAGEIYVMVNDKPVCKPCYVKNHAVVCQGCHNAIDPEVQRVTYNNFSWHA 384
F C C LA E + + + +C CY + C C + P +++ Y +WH
Sbjct: 65 CFRCCRCQRSLADEPFTCQDSELLCNDCYCSAFSSQCSACGETVMPGSRKLEYGGQTWH- 123
Query: 385 STECFLCSCCSKCLIGQKFMPVEGMVFC 412
CFLCS C + L + F+P +G +C
Sbjct: 124 -EHCFLCSGCEQPLGSRSFVPDKGAHYC 150
Score = 60.1 bits (144), Expect = 4e-09
Identities = 28/98 (28%), Positives = 47/98 (47%), Gaps = 3/98 (3%)
Query: 258 DKLWHPACFVCSTCHELLVDMIYFWKNEKLYCGRHYCDSEKPRCAGCDELIF---SNEYT 314
D+ WH C VC+ C L + ++E YC + + P+C+ C I +Y
Sbjct: 178 DQPWHRECLVCTGCQTPLAGQQFTSRDEDPYCVACFGELFAPKCSSCKRPIVGLGGGKYV 237
Query: 315 QAENQNWHLKHFCCFDCDSILAGEIYVMVNDKPVCKPC 352
E+++WH F C C + L G+ +V D+ +C+ C
Sbjct: 238 SFEDRHWHHNCFSCARCSTSLVGQGFVPDGDQVLCQGC 275
Score = 50.8 bits (120), Expect = 2e-06
Identities = 24/88 (27%), Positives = 37/88 (42%), Gaps = 2/88 (2%)
Query: 326 FCCFDCDSILAGEIYVMVNDKPVCKPCYVKNHAVVCQGCHNAIDPEVQRVTYNNFSWHAS 385
F C C+ L G Y+ + P C PCY A C C I + + + Y + +H
Sbjct: 5 FDCAKCNESLYGRKYIQTDSGPYCVPCYDNTFANTCAECQQLIGHDSRELFYEDRHFHEG 64
Query: 386 TECFLCSCCSKCLIGQKFMPVEGMVFCS 413
CF C C + L + F + + C+
Sbjct: 65 --CFRCCRCQRSLADEPFTCQDSELLCN 90
>gi|30410801 activator of cAMP-responsive element modulator (CREM)
in testis [Homo sapiens]
Length = 284
Score = 84.0 bits (206), Expect = 2e-16
Identities = 46/156 (29%), Positives = 69/156 (44%), Gaps = 5/156 (3%)
Query: 258 DKLWHPACFVCSTCHELLVDMIYFWKNEKLYCGRHYCDSEKPRCAGCDELIF-SNEYTQA 316
D+ WH CF C+ C+ LV+ + K+E+L C Y + +C C I + +
Sbjct: 59 DRHWHEGCFKCTKCNHSLVEKPFAAKDERLLCTECYSNECSSKCFHCKRTIMPGSRKMEF 118
Query: 317 ENQNWHLKHFCCFDCDSILAGEIYVMVNDKPVCKPCYVKNHAVVCQGCHNAIDPEVQRVT 376
+ WH F C +C + + + C PC+ K A C C I +T
Sbjct: 119 KGNYWHETCFVCENCRQPIGTKPLISKESGNYCVPCFEKEFAHYCNFCKKVITS--GGIT 176
Query: 377 YNNFSWHASTECFLCSCCSKCLIGQKFMPVEGMVFC 412
+ + WH ECFLCS C K L ++FM + FC
Sbjct: 177 FCDQLWH--KECFLCSGCRKDLCEEQFMSRDDYPFC 210
Score = 79.7 bits (195), Expect = 5e-15
Identities = 49/179 (27%), Positives = 74/179 (41%), Gaps = 9/179 (5%)
Query: 236 CYCCKLSMKEGDPAIYAERAGYDKLWHPACFVCSTCHELLVDMIYFWKNEKLYCGRHYCD 295
C+ CK ++ G + + WH CFVC C + + K YC +
Sbjct: 102 CFHCKRTIMPGSRKMEFK----GNYWHETCFVCENCRQPIGTKPLISKESGNYCVPCFEK 157
Query: 296 SEKPRCAGCDELIFSNEYTQAENQNWHLKHFCCFDCDSILAGEIYVMVNDKPVCKPCYVK 355
C C ++I S T + Q WH + F C C L E ++ +D P C CY
Sbjct: 158 EFAHYCNFCKKVITSGGITFCD-QLWHKECFLCSGCRKDLCEEQFMSRDDYPFCMDCYNH 216
Query: 356 NHAVVCQGCHNAID--PEVQRVTYNNFSWHASTECFLCSCCSKCLIGQKFMPVEGMVFC 412
+A C C I + + + + WH +ECF C CS L+G+ F+ +FC
Sbjct: 217 LYANKCVACSKPISGLTGAKFICFQDSQWH--SECFNCGKCSVSLVGKGFLTQNKEIFC 273
Score = 59.7 bits (143), Expect = 5e-09
Identities = 28/92 (30%), Positives = 47/92 (51%), Gaps = 3/92 (3%)
Query: 325 HFCCFDCDSILAGEIYVMVNDKPVCKPCYVKNHAVVCQGCHNAIDPEVQRVTYNNFSWHA 384
HF C C + L G+ YV+ +D P C CY + + C+ C I+ + + + Y + WH
Sbjct: 5 HFYCQYCTASLLGKKYVLKDDSPYCVTCYDRVFSNYCEECKKPIESDSKDLCYKDRHWHE 64
Query: 385 STECFLCSCCSKCLIGQKFMPVEGMVFCSVEC 416
CF C+ C+ L+ + F + + C+ EC
Sbjct: 65 G--CFKCTKCNHSLVEKPFAAKDERLLCT-EC 93
Score = 56.2 bits (134), Expect = 5e-08
Identities = 35/150 (23%), Positives = 63/150 (42%), Gaps = 3/150 (2%)
Query: 264 ACFVCSTCHELLVDMIYFWKNEKLYCGRHYCDSEKPRCAGCDELIFSNEYTQA-ENQNWH 322
A F C C L+ Y K++ YC Y C C + I S+ ++++WH
Sbjct: 4 AHFYCQYCTASLLGKKYVLKDDSPYCVTCYDRVFSNYCEECKKPIESDSKDLCYKDRHWH 63
Query: 323 LKHFCCFDCDSILAGEIYVMVNDKPVCKPCYVKNHAVVCQGCHNAIDPEVQRVTYNNFSW 382
F C C+ L + + +++ +C CY + C C I P +++ + W
Sbjct: 64 EGCFKCTKCNHSLVEKPFAAKDERLLCTECYSNECSSKCFHCKRTIMPGSRKMEFKGNYW 123
Query: 383 HASTECFLCSCCSKCLIGQKFMPVEGMVFC 412
H + CF+C C + + + + E +C
Sbjct: 124 HET--CFVCENCRQPIGTKPLISKESGNYC 151
Score = 51.6 bits (122), Expect = 1e-06
Identities = 25/98 (25%), Positives = 46/98 (46%), Gaps = 3/98 (3%)
Query: 258 DKLWHPACFVCSTCHELLVDMIYFWKNEKLYCGRHYCDSEKPRCAGCDELI---FSNEYT 314
D+LWH CF+CS C + L + + +++ +C Y +C C + I ++
Sbjct: 179 DQLWHKECFLCSGCRKDLCEEQFMSRDDYPFCMDCYNHLYANKCVACSKPISGLTGAKFI 238
Query: 315 QAENQNWHLKHFCCFDCDSILAGEIYVMVNDKPVCKPC 352
++ WH + F C C L G+ ++ N + C+ C
Sbjct: 239 CFQDSQWHSECFNCGKCSVSLVGKGFLTQNKEIFCQKC 276
>gi|109638745 transforming growth factor beta 1 induced transcript 1
isoform 1 [Homo sapiens]
Length = 461
Score = 81.6 bits (200), Expect = 1e-15
Identities = 60/238 (25%), Positives = 92/238 (38%), Gaps = 23/238 (9%)
Query: 189 VGDVKLPCEMDAQGPKQMNI-------------PGGDRSTPAAVGAME-DKSAEHKRTQY 234
+ D ++ + A GP Q + P G S +G ++ D S TQ
Sbjct: 165 LSDFRVQNHLPASGPTQPPVVSSTNEGSPSPPEPTGKGSLDTMLGLLQSDLSRRGVPTQA 224
Query: 235 SCYCCKLSMKEGDPAIYAERAGYDKLWHPACFVCSTCHELLVDMIYFWKNEKLYCGRHYC 294
C + + A + WHP FVC C L +F K+ +C Y
Sbjct: 225 KGLCGSCNKPIAGQVVTA----LGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYF 280
Query: 295 DSEKPRCAGCDELIFSNEYTQAENQNWHLKHFCCFDCDSILAGEIYVMVNDKPVCKPCYV 354
+ PRC C++ I ++ A +WH +HFCC C E + +P C+ ++
Sbjct: 281 ERFSPRCGFCNQPI-RHKMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFL 339
Query: 355 KNHAVVCQGCHNAIDPEVQRVTYNNFSWHASTECFLCSCCSKCLIGQKFMPVEGMVFC 412
+ A CQGC I ++ + WH +CF+C C G F EG C
Sbjct: 340 QLFAPRCQGCQGPILDNY--ISALSALWH--PDCFVCRECFAPFSGGSFFEHEGRPLC 393
Score = 62.0 bits (149), Expect = 1e-09
Identities = 38/152 (25%), Positives = 58/152 (38%), Gaps = 5/152 (3%)
Query: 261 WHPACFVCSTCHELLVDMIYFWKNEKLYCGRHYCDSEKPRCAGCDELIFSNEYTQAENQN 320
WHP F C +C E D + + + YC R + PRC GC I N Y A +
Sbjct: 306 WHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFAPRCQGCQGPILDN-YISALSAL 364
Query: 321 WHLKHFCCFDCDSILAGEIYVMVNDKPVCKPCYVKNHAVVCQGCHNAIDPEVQRVTYNNF 380
WH F C +C + +G + +P+C+ + +C C + F
Sbjct: 365 WHPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRGSLCATCGLPVTGRCVSALGRRF 424
Query: 381 SWHASTECFLCSCCSKCLIGQKFMPVEGMVFC 412
+ F C+ C + L F G +C
Sbjct: 425 ----HPDHFTCTFCLRPLTKGSFQERAGKPYC 452
Score = 53.1 bits (126), Expect = 5e-07
Identities = 29/96 (30%), Positives = 39/96 (40%), Gaps = 1/96 (1%)
Query: 260 LWHPACFVCSTCHELLVDMIYFWKNEKLYCGRHYCDSEKPRCAGCDELIFSNEYTQAENQ 319
LWHP CFVC C +F + C H+ CA C L + A +
Sbjct: 364 LWHPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRGSLCATCG-LPVTGRCVSALGR 422
Query: 320 NWHLKHFCCFDCDSILAGEIYVMVNDKPVCKPCYVK 355
+H HF C C L + KP C+PC++K
Sbjct: 423 RFHPDHFTCTFCLRPLTKGSFQERAGKPYCQPCFLK 458
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.135 0.441
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,897,077
Number of Sequences: 37866
Number of extensions: 859580
Number of successful extensions: 3086
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 106
Number of HSP's successfully gapped in prelim test: 51
Number of HSP's that attempted gapping in prelim test: 2323
Number of HSP's gapped (non-prelim): 429
length of query: 421
length of database: 18,247,518
effective HSP length: 105
effective length of query: 316
effective length of database: 14,271,588
effective search space: 4509821808
effective search space used: 4509821808
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.