BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|7657655 translocation associated membrane protein 1 [Homo sapiens] (374 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|7657655 translocation associated membrane protein 1 [Homo sap... 747 0.0 gi|145580602 translocation associated membrane protein 1-like 1 ... 539 e-153 gi|6912450 translocation-associated membrane protein 2 [Homo sap... 398 e-111 gi|45007002 longevity assurance homolog 6 [Homo sapiens] 57 2e-08 gi|205360977 LAG1 homolog, ceramide synthase 4 [Homo sapiens] 56 5e-08 gi|32455256 LAG1 longevity assurance 2 [Homo sapiens] 56 6e-08 gi|31077094 LAG1 longevity assurance 2 [Homo sapiens] 56 6e-08 gi|22218345 LAG1 homolog, ceramide synthase 5 [Homo sapiens] 52 9e-07 gi|116235446 LAG1 longevity assurance homolog 3 [Homo sapiens] 45 8e-05 gi|49533617 sterol O-acyltransferase 1 [Homo sapiens] 32 1.2 gi|169216272 PREDICTED: hypothetical protein [Homo sapiens] 30 3.5 gi|169216572 PREDICTED: hypothetical protein [Homo sapiens] 30 3.5 gi|58219014 solute carrier family 6, member 17 [Homo sapiens] 30 4.6 gi|224586786 natural cytotoxicity triggering receptor 1 isoform ... 30 4.6 gi|4758692 natural cytotoxicity triggering receptor 1 isoform a ... 29 6.0 gi|33598944 polycystic kidney disease 2-like 1 [Homo sapiens] 29 6.0 >gi|7657655 translocation associated membrane protein 1 [Homo sapiens] Length = 374 Score = 747 bits (1928), Expect = 0.0 Identities = 374/374 (100%), Positives = 374/374 (100%) Query: 1 MAIRKKSTKSPPVLSHEFVLQNHADIVSCVAMVFLLGLMFEITAKASIIFVTLQYNVTLP 60 MAIRKKSTKSPPVLSHEFVLQNHADIVSCVAMVFLLGLMFEITAKASIIFVTLQYNVTLP Sbjct: 1 MAIRKKSTKSPPVLSHEFVLQNHADIVSCVAMVFLLGLMFEITAKASIIFVTLQYNVTLP 60 Query: 61 ATEEQATESVSLYYYGIKDLATVFFYMLVAIIIHAVIQEYMLDKINRRMHFSKTKHSKFN 120 ATEEQATESVSLYYYGIKDLATVFFYMLVAIIIHAVIQEYMLDKINRRMHFSKTKHSKFN Sbjct: 61 ATEEQATESVSLYYYGIKDLATVFFYMLVAIIIHAVIQEYMLDKINRRMHFSKTKHSKFN 120 Query: 121 ESGQLSAFYLFACVWGTFILISENYISDPTILWRAYPHNLMTFQMKFFYISQLAYWLHAF 180 ESGQLSAFYLFACVWGTFILISENYISDPTILWRAYPHNLMTFQMKFFYISQLAYWLHAF Sbjct: 121 ESGQLSAFYLFACVWGTFILISENYISDPTILWRAYPHNLMTFQMKFFYISQLAYWLHAF 180 Query: 181 PELYFQKTKKEDIPRQLVYIGLYLFHIAGAYLLNLNHLGLVLLVLHYFVEFLFHISRLFY 240 PELYFQKTKKEDIPRQLVYIGLYLFHIAGAYLLNLNHLGLVLLVLHYFVEFLFHISRLFY Sbjct: 181 PELYFQKTKKEDIPRQLVYIGLYLFHIAGAYLLNLNHLGLVLLVLHYFVEFLFHISRLFY 240 Query: 241 FSNEKYQKGFSLWAVLFVLGRLLTLILSVLTVGFGLARAENQKLDFSTGNFNVLAVRIAV 300 FSNEKYQKGFSLWAVLFVLGRLLTLILSVLTVGFGLARAENQKLDFSTGNFNVLAVRIAV Sbjct: 241 FSNEKYQKGFSLWAVLFVLGRLLTLILSVLTVGFGLARAENQKLDFSTGNFNVLAVRIAV 300 Query: 301 LASICVTQAFMMWKFINFQLRRWREHSAFQAPAVKKKPTVTKGRSSKKGTENGVNGTLTS 360 LASICVTQAFMMWKFINFQLRRWREHSAFQAPAVKKKPTVTKGRSSKKGTENGVNGTLTS Sbjct: 301 LASICVTQAFMMWKFINFQLRRWREHSAFQAPAVKKKPTVTKGRSSKKGTENGVNGTLTS 360 Query: 361 NVADSPRNKKEKSS 374 NVADSPRNKKEKSS Sbjct: 361 NVADSPRNKKEKSS 374 >gi|145580602 translocation associated membrane protein 1-like 1 [Homo sapiens] Length = 369 Score = 539 bits (1388), Expect = e-153 Identities = 267/374 (71%), Positives = 311/374 (83%), Gaps = 5/374 (1%) Query: 1 MAIRKKSTKSPPVLSHEFVLQNHADIVSCVAMVFLLGLMFEITAKASIIFVTLQYNVTLP 60 M +RKKSTK+PPVLS EF+LQNHADIVSCV M FLLGL+FE TA+ASI+F+TLQ++V +P Sbjct: 1 MGLRKKSTKNPPVLSQEFILQNHADIVSCVGMFFLLGLVFEGTAEASIVFLTLQHSVAVP 60 Query: 61 ATEEQATESVSLYYYGIKDLATVFFYMLVAIIIHAVIQEYMLDKINRRMHFSKTKHSKFN 120 A EEQAT S SLYYYG+KDLATVFFYMLVAIIIHA IQEY+LDKIN+RM F+K K +KFN Sbjct: 61 AAEEQATGSKSLYYYGVKDLATVFFYMLVAIIIHATIQEYVLDKINKRMQFTKAKQNKFN 120 Query: 121 ESGQLSAFYLFACVWGTFILISENYISDPTILWRAYPHNLMTFQMKFFYISQLAYWLHAF 180 ESGQ S FY F+C+WGTFILISEN +SDPT++W+A PH++MTFQMKFFYISQLAYW HAF Sbjct: 121 ESGQFSVFYFFSCIWGTFILISENCLSDPTLIWKARPHSMMTFQMKFFYISQLAYWFHAF 180 Query: 181 PELYFQKTKKEDIPRQLVYIGLYLFHIAGAYLLNLNHLGLVLLVLHYFVEFLFHISRLFY 240 PELYFQKTKK+DIPRQLVYIGL+LFHI GAYLL LNHLGL+LLVLHYFVE L H+ LFY Sbjct: 181 PELYFQKTKKQDIPRQLVYIGLHLFHITGAYLLYLNHLGLLLLVLHYFVELLSHMCGLFY 240 Query: 241 FSNEKYQKGFSLWAVLFVLGRLLTLILSVLTVGFGLARAENQKLDFSTGNFNVLAVRIAV 300 FS+EKYQKG SLWA++F+LGRL+TLI+SVLTVGF LA ++N+ D TGN NVLA +IAV Sbjct: 241 FSDEKYQKGISLWAIVFILGRLVTLIVSVLTVGFHLAGSQNRNPDALTGNVNVLAAKIAV 300 Query: 301 LASICVTQAFMMWKFINFQLRRWREHSAFQAPAVKKKPTVTKGRSSKKGTENGVNGTLTS 360 L+S C QA++ W I L+RW E S QA +KKK + RSSKK TENGV G TS Sbjct: 301 LSSSCTIQAYVTWNLITLWLQRWVEDSNIQASCMKKK----RSRSSKKRTENGV-GVETS 355 Query: 361 NVADSPRNKKEKSS 374 N D P +KEKSS Sbjct: 356 NRVDCPPKRKEKSS 369 >gi|6912450 translocation-associated membrane protein 2 [Homo sapiens] Length = 370 Score = 398 bits (1023), Expect = e-111 Identities = 195/375 (52%), Positives = 263/375 (70%), Gaps = 8/375 (2%) Query: 1 MAIRKKSTKSPPVLSHEFVLQNHADIVSCVAMVFLLGLMFEITAKASIIFVTLQYNVTLP 60 MA R++ TKS P+ S EFV+ NHADI C+ + L+GLMFE+TAK + +F+ QYN+++P Sbjct: 1 MAFRRR-TKSYPLFSQEFVIHNHADIGFCLVLCVLIGLMFEVTAKTAFLFILPQYNISVP 59 Query: 61 ATEEQATESVSLYYYGIKDLATVFFYMLVAIIIHAVIQEYMLDKINRRMHFSKTKHSKFN 120 + + Y+YG KDL T+ FY+ + II+HAV+QEY+LDKI++R+H SK KHSKFN Sbjct: 60 TADSETVH----YHYGPKDLVTILFYIFITIILHAVVQEYILDKISKRLHLSKVKHSKFN 115 Query: 121 ESGQLSAFYLFACVWGTFILISENYISDPTILWRAYPHNLMTFQMKFFYISQLAYWLHAF 180 ESGQL F+ + +W +++++E Y+++P LW YPH + FQ+KFFY+ QLAYWLHA Sbjct: 116 ESGQLVVFHFTSVIWCFYVVVTEGYLTNPRSLWEDYPHVHLPFQVKFFYLCQLAYWLHAL 175 Query: 181 PELYFQKTKKEDIPRQLVYIGLYLFHIAGAYLLNLNHLGLVLLVLHYFVEFLFHISRLFY 240 PELYFQK +KE+IPRQL YI LYL HIAGAYLLNL+ LGL+LL+L Y EFLFH +RLFY Sbjct: 176 PELYFQKVRKEEIPRQLQYICLYLVHIAGAYLLNLSRLGLILLLLQYSTEFLFHTARLFY 235 Query: 241 FSNEKYQKGFSLWAVLFVLGRLLTLILSVLTVGFGLARAENQKLDFSTGNFNVLAVRIAV 300 F++E +K FS WA +F + RL L L+VL +GFGLAR ENQ D GNFN L R+ V Sbjct: 236 FADENNEKLFSAWAAVFGVTRLFILTLAVLAIGFGLARMENQAFDPEKGNFNTLFCRLCV 295 Query: 301 LASICVTQAFMMWKFINFQLRRWREHSAFQAPAVKKKPTVTK--GRSSKKGTENGVNGTL 358 L +C QA++MW+FI+ QLR WRE+ Q+ A ++ P + R K+ + NG + Sbjct: 296 LLLVCAAQAWLMWRFIHSQLRHWREYWNEQS-AKRRVPATPRLPARLIKRESGYHENGVV 354 Query: 359 TSNVADSPRNKKEKS 373 + SPR KK KS Sbjct: 355 KAENGTSPRTKKLKS 369 >gi|45007002 longevity assurance homolog 6 [Homo sapiens] Length = 384 Score = 57.4 bits (137), Expect = 2e-08 Identities = 44/169 (26%), Positives = 84/169 (49%), Gaps = 9/169 (5%) Query: 107 RRMHFSKTKHSKFNESGQLSAFYLFACVWGTFILISENYISDPTILWRAYPHNLMTFQMK 166 RR + ++F ES +FYL+ +G L ++ + W YP+ +T + Sbjct: 120 RRNQEKPSTLTRFCESMWRFSFYLYVFTYGVRFLKKTPWLWNTRHCWYNYPYQPLTTDLH 179 Query: 167 FFYISQLA-YWLHAFPELYFQKTKKEDIPRQLVYIGLYLFHIAGAYLLNLNHLGLVLLVL 225 ++YI +L+ YW F + F K++D ++ + +F I +Y+ N+ +G ++L L Sbjct: 180 YYYILELSFYWSLMFSQ--FTDIKRKDFGIMFLHHLVSIFLITFSYVNNMARVGTLVLCL 237 Query: 226 HYFVEFLFHISRLFYFSNEKYQKG----FSLWAVLFVLGRLLTLILSVL 270 H + L +++ ++ K+QK F ++AV+F+ RL L VL Sbjct: 238 HDSADALLEAAKMANYA--KFQKMCDLLFVMFAVVFITTRLGIFPLWVL 284 >gi|205360977 LAG1 homolog, ceramide synthase 4 [Homo sapiens] Length = 394 Score = 56.2 bits (134), Expect = 5e-08 Identities = 37/157 (23%), Positives = 79/157 (50%), Gaps = 7/157 (4%) Query: 118 KFNESGQLSAFYLFACVWGTFILISENYISDPTILWRAYPHNLMTFQMKFFYISQLAYWL 177 KF E+ FYL + V G +L E+++ P + W YP+ + + ++Y+ +L ++L Sbjct: 132 KFCEASWRFLFYLSSFVGGLSVLYHESWLWAPVMCWDRYPNQTLKPSLYWWYLLELGFYL 191 Query: 178 HAFPELYFQKTKKEDIPRQLVYIGLYLFHIAGAYLLNLNHLGLVLLVLHYFVEFLFHISR 237 L F K++D Q+++ + + + +Y NL +G ++L+LH ++L + Sbjct: 192 SLLIRLPFD-VKRKDFKEQVIHHFVAVILMTFSYSANLLRIGSLVLLLHDSSDYLLEACK 250 Query: 238 LFYFSNEKYQKG----FSLWAVLFVLGRLLTLILSVL 270 + + +YQ+ F +++ +F RL+ +L Sbjct: 251 MVNYM--QYQQVCDALFLIFSFVFFYTRLVLFPTQIL 285 >gi|32455256 LAG1 longevity assurance 2 [Homo sapiens] Length = 380 Score = 55.8 bits (133), Expect = 6e-08 Identities = 35/156 (22%), Positives = 75/156 (48%), Gaps = 5/156 (3%) Query: 118 KFNESGQLSAFYLFACVWGTFILISENYISDPTILWRAYPHNLMTFQMKFFYISQLA-YW 176 KF E+ FYL A + G +++ + + D +W YP ++Y+ +L+ YW Sbjct: 132 KFREASWRFTFYLIAFIAGMAVIVDKPWFYDMKKVWEGYPIQSTIPSQYWYYMIELSFYW 191 Query: 177 LHAFPELYFQKTKKEDIPRQLVYIGLYLFHIAGAYLLNLNHLGLVLLVLHYFVEFLFHIS 236 F K++D Q+++ + I+ ++ N G +++ LH ++L + Sbjct: 192 SLLFS--IASDVKRKDFKEQIIHHVATIILISFSWFANYIRAGTLIMALHDSSDYLLESA 249 Query: 237 RLFYFSNEK--YQKGFSLWAVLFVLGRLLTLILSVL 270 ++F ++ K F ++A++F++ RL+ L +L Sbjct: 250 KMFNYAGWKNTCNNIFIVFAIVFIITRLVILPFWIL 285 >gi|31077094 LAG1 longevity assurance 2 [Homo sapiens] Length = 380 Score = 55.8 bits (133), Expect = 6e-08 Identities = 35/156 (22%), Positives = 75/156 (48%), Gaps = 5/156 (3%) Query: 118 KFNESGQLSAFYLFACVWGTFILISENYISDPTILWRAYPHNLMTFQMKFFYISQLA-YW 176 KF E+ FYL A + G +++ + + D +W YP ++Y+ +L+ YW Sbjct: 132 KFREASWRFTFYLIAFIAGMAVIVDKPWFYDMKKVWEGYPIQSTIPSQYWYYMIELSFYW 191 Query: 177 LHAFPELYFQKTKKEDIPRQLVYIGLYLFHIAGAYLLNLNHLGLVLLVLHYFVEFLFHIS 236 F K++D Q+++ + I+ ++ N G +++ LH ++L + Sbjct: 192 SLLFS--IASDVKRKDFKEQIIHHVATIILISFSWFANYIRAGTLIMALHDSSDYLLESA 249 Query: 237 RLFYFSNEK--YQKGFSLWAVLFVLGRLLTLILSVL 270 ++F ++ K F ++A++F++ RL+ L +L Sbjct: 250 KMFNYAGWKNTCNNIFIVFAIVFIITRLVILPFWIL 285 >gi|22218345 LAG1 homolog, ceramide synthase 5 [Homo sapiens] Length = 392 Score = 52.0 bits (123), Expect = 9e-07 Identities = 45/155 (29%), Positives = 75/155 (48%), Gaps = 17/155 (10%) Query: 117 SKFNESGQLSAFYLFACVWGTFILISENYISDPTILWRAYPHNLMTFQMKFFYISQLA-Y 175 +KF ES FYL +G L S + D W YP ++ + +YI +LA Y Sbjct: 139 TKFCESMWRFTFYLCIFCYGIRFLWSSPWFWDIRQCWHNYPFQPLSSGLYHYYIMELAFY 198 Query: 176 WLHAFPELYFQKTKKED----IPRQLVYIGLYLFHIAGAYLLNLNHLGLVLLVLHYFVEF 231 W F + F K++D LV IGL F +Y+ N+ +G +++ LH +F Sbjct: 199 WSLMFSQ--FTDIKRKDFLIMFVHHLVTIGLISF----SYINNMVRVGTLIMCLHDVSDF 252 Query: 232 LFHISRLFYFSNEKYQK----GFSLWAVLFVLGRL 262 L ++L ++ KYQ+ F +++ +F++ RL Sbjct: 253 LLEAAKLANYA--KYQRLCDTLFVIFSAVFMVTRL 285 >gi|116235446 LAG1 longevity assurance homolog 3 [Homo sapiens] Length = 383 Score = 45.4 bits (106), Expect = 8e-05 Identities = 31/167 (18%), Positives = 76/167 (45%), Gaps = 3/167 (1%) Query: 106 NRRMHFSKTKHSKFNESGQLSAFYLFACVWGTFILISENYISDPTILWRAYPHNLMTFQM 165 +RR ++ KF E+ AFYL V G L + ++ D +W YP + Sbjct: 119 SRRNQERPSRLKKFQEACWRFAFYLMITVAGIAFLYDKPWLYDLWEVWNGYPKQPLLPSQ 178 Query: 166 KFFYISQLAYWLHAFPELYFQKTKKEDIPRQLVYIGLYLFHIAGAYLLNLNHLGLVLLVL 225 ++YI +++++ L F K++D +++ + ++ ++ N G +++++ Sbjct: 179 YWYYILEMSFYWSLLFRLGFD-VKRKDFLAHIIHHLAAISLMSFSWCANYIRSGTLVMIV 237 Query: 226 HYFVEFLFHISRLFYFS--NEKYQKGFSLWAVLFVLGRLLTLILSVL 270 H + +++F ++ + F +++ +F + RL+ +L Sbjct: 238 HDVADIWLESAKMFSYAGWTQTCNTLFFIFSTIFFISRLIVFPFWIL 284 >gi|49533617 sterol O-acyltransferase 1 [Homo sapiens] Length = 550 Score = 31.6 bits (70), Expect = 1.2 Identities = 28/132 (21%), Positives = 56/132 (42%), Gaps = 10/132 (7%) Query: 128 FYLFACVWGTFILISENYISDPTILWRAYPHNLMTFQMKFFYISQLAYWLHAFPELYFQK 187 ++LFA ++ ++Y +PT+ W FFY+ + L A F+ Sbjct: 299 YFLFAPT----LIYRDSYPRNPTVRWGYVAMKFAQVFGCFFYVYYIFERLCA---PLFRN 351 Query: 188 TKKEDIPRQLVYIGLYLFHIAGAYLLNLNHLGLVLLVLHYFVEFLFHISRLFY---FSNE 244 K+E +++ + ++ + G +L L + L+ F E L R+FY +++ Sbjct: 352 IKQEPFSARVLVLCVFNSILPGVLILFLTFFAFLHCWLNAFAEMLRFGDRMFYKDWWNST 411 Query: 245 KYQKGFSLWAVL 256 Y + W V+ Sbjct: 412 SYSNYYRTWNVV 423 >gi|169216272 PREDICTED: hypothetical protein [Homo sapiens] Length = 753 Score = 30.0 bits (66), Expect = 3.5 Identities = 13/30 (43%), Positives = 18/30 (60%) Query: 320 LRRWREHSAFQAPAVKKKPTVTKGRSSKKG 349 LR + S F+AP K P +T+ RS+ KG Sbjct: 246 LRTLKATSIFEAPCTSKDPRITRARSTLKG 275 >gi|169216572 PREDICTED: hypothetical protein [Homo sapiens] Length = 753 Score = 30.0 bits (66), Expect = 3.5 Identities = 13/30 (43%), Positives = 18/30 (60%) Query: 320 LRRWREHSAFQAPAVKKKPTVTKGRSSKKG 349 LR + S F+AP K P +T+ RS+ KG Sbjct: 246 LRTLKATSIFEAPCTSKDPRITRARSTLKG 275 >gi|58219014 solute carrier family 6, member 17 [Homo sapiens] Length = 727 Score = 29.6 bits (65), Expect = 4.6 Identities = 19/55 (34%), Positives = 30/55 (54%), Gaps = 5/55 (9%) Query: 27 VSCVAMVFLLGLMFEITAKASIIFVTL--QYNVTLPATEEQATESVSL-YYYGIK 78 V C FL+GL+F ++ FVT+ Y+ TLP T E++++ + YG K Sbjct: 498 VGCCVFAFLVGLLF--VQRSGNYFVTMFDDYSATLPLTLIVILENIAVAWIYGTK 550 >gi|224586786 natural cytotoxicity triggering receptor 1 isoform b [Homo sapiens] Length = 303 Score = 29.6 bits (65), Expect = 4.6 Identities = 13/47 (27%), Positives = 22/47 (46%) Query: 131 FACVWGTFILISENYISDPTILWRAYPHNLMTFQMKFFYISQLAYWL 177 F WGT++L +E + LW NL+ + F + L ++L Sbjct: 226 FPDTWGTYLLTTETGLQKDHALWDHTAQNLLRMGLAFLVLVALVWFL 272 >gi|4758692 natural cytotoxicity triggering receptor 1 isoform a [Homo sapiens] Length = 304 Score = 29.3 bits (64), Expect = 6.0 Identities = 13/46 (28%), Positives = 22/46 (47%) Query: 132 ACVWGTFILISENYISDPTILWRAYPHNLMTFQMKFFYISQLAYWL 177 A WGT++L +E + LW NL+ + F + L ++L Sbjct: 228 ADTWGTYLLTTETGLQKDHALWDHTAQNLLRMGLAFLVLVALVWFL 273 >gi|33598944 polycystic kidney disease 2-like 1 [Homo sapiens] Length = 805 Score = 29.3 bits (64), Expect = 6.0 Identities = 23/82 (28%), Positives = 39/82 (47%), Gaps = 20/82 (24%) Query: 199 YIGLYLFHIAGAYLLNLNHLGLVLLVLHYFVEFLF--HISRLFYFSNEKYQKGFSLWAVL 256 Y+ + F I G ++ + + +Y VE + HI RL Y S S+W +L Sbjct: 344 YVSNWDFFIVGCEVI------FCVFIFYYVVEEILELHIHRLRYLS--------SIWNIL 389 Query: 257 FVLGRLLTLILSVLTVGFGLAR 278 L+ ++LS++ VGF + R Sbjct: 390 ----DLVVILLSIVAVGFHIFR 407 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.327 0.138 0.415 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 12,283,984 Number of Sequences: 37866 Number of extensions: 470809 Number of successful extensions: 1403 Number of sequences better than 10.0: 16 Number of HSP's better than 10.0 without gapping: 13 Number of HSP's successfully gapped in prelim test: 3 Number of HSP's that attempted gapping in prelim test: 1385 Number of HSP's gapped (non-prelim): 17 length of query: 374 length of database: 18,247,518 effective HSP length: 104 effective length of query: 270 effective length of database: 14,309,454 effective search space: 3863552580 effective search space used: 3863552580 T: 11 A: 40 X1: 15 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.7 bits) S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.