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Search of human proteins with 7657625
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7657625 staufen homolog 2 [Homo sapiens]
(479 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7657625 staufen homolog 2 [Homo sapiens] 957 0.0
gi|82659087 staufen isoform b [Homo sapiens] 395 e-110
gi|82659089 staufen isoform a [Homo sapiens] 370 e-102
gi|82659085 staufen isoform a [Homo sapiens] 370 e-102
gi|82659083 staufen isoform a [Homo sapiens] 370 e-102
gi|82659091 staufen isoform c [Homo sapiens] 364 e-100
gi|19743838 TAR RNA binding protein 2 isoform b [Homo sapiens] 79 7e-15
gi|19743840 TAR RNA binding protein 2 isoform a [Homo sapiens] 79 7e-15
gi|85068512 TAR RNA binding protein 2 isoform b [Homo sapiens] 79 7e-15
gi|213417919 protein kinase, interferon-inducible double strande... 79 1e-14
gi|213417911 protein kinase, interferon-inducible double strande... 79 1e-14
gi|4505581 protein kinase, interferon-inducible double stranded ... 79 1e-14
gi|212549555 interleukin enhancer binding factor 3 isoform e [Ho... 66 8e-11
gi|212549553 interleukin enhancer binding factor 3 isoform d [Ho... 66 8e-11
gi|24234756 interleukin enhancer binding factor 3 isoform c [Hom... 65 1e-10
gi|24234753 interleukin enhancer binding factor 3 isoform b [Hom... 65 1e-10
gi|24234750 interleukin enhancer binding factor 3 isoform a [Hom... 65 1e-10
gi|70167032 adenosine deaminase, RNA-specific isoform c [Homo sa... 58 2e-08
gi|21361745 spermatid perinuclear RNA binding protein [Homo sapi... 58 2e-08
gi|70167113 adenosine deaminase, RNA-specific isoform d [Homo sa... 55 1e-07
gi|70166944 adenosine deaminase, RNA-specific isoform b [Homo sa... 55 1e-07
gi|70166852 adenosine deaminase, RNA-specific isoform a [Homo sa... 55 1e-07
gi|237681091 RNA-specific adenosine deaminase B1 isoform 7 [Homo... 53 7e-07
gi|7669479 RNA-specific adenosine deaminase B1 isoform 3 [Homo s... 53 7e-07
gi|7669477 RNA-specific adenosine deaminase B1 isoform 2 [Homo s... 53 7e-07
gi|4501919 RNA-specific adenosine deaminase B1 isoform 1 [Homo s... 53 7e-07
gi|208431829 eukaryotic translation initiation factor 2-alpha ki... 51 2e-06
gi|208431827 eukaryotic translation initiation factor 2-alpha ki... 51 2e-06
gi|4506103 eukaryotic translation initiation factor 2-alpha kina... 51 2e-06
gi|8922077 adenosine deaminase, RNA-specific, B2 [Homo sapiens] 49 8e-06
>gi|7657625 staufen homolog 2 [Homo sapiens]
Length = 479
Score = 957 bits (2475), Expect = 0.0
Identities = 479/479 (100%), Positives = 479/479 (100%)
Query: 1 MLQINQMFSVQLSLGEQTWESEGSSIKKAQQAVANKALTESTLPKPVQKPPKSNVNNNPG 60
MLQINQMFSVQLSLGEQTWESEGSSIKKAQQAVANKALTESTLPKPVQKPPKSNVNNNPG
Sbjct: 1 MLQINQMFSVQLSLGEQTWESEGSSIKKAQQAVANKALTESTLPKPVQKPPKSNVNNNPG 60
Query: 61 SITPTVELNGLAMKRGEPAIYRPLDPKPFPNYRANYNFRGMYNQRYHCPVPKIFYVQLTV 120
SITPTVELNGLAMKRGEPAIYRPLDPKPFPNYRANYNFRGMYNQRYHCPVPKIFYVQLTV
Sbjct: 61 SITPTVELNGLAMKRGEPAIYRPLDPKPFPNYRANYNFRGMYNQRYHCPVPKIFYVQLTV 120
Query: 121 GNNEFFGEGKTRQAARHNAAMKALQALQNEPIPERSPQNGESGKDMDDDKDANKSEISLV 180
GNNEFFGEGKTRQAARHNAAMKALQALQNEPIPERSPQNGESGKDMDDDKDANKSEISLV
Sbjct: 121 GNNEFFGEGKTRQAARHNAAMKALQALQNEPIPERSPQNGESGKDMDDDKDANKSEISLV 180
Query: 181 FEIALKRNMPVSFEVIKESGPPHMKSFVTRVSVGEFSAEGEGNSKKLSKKRAATTVLQEL 240
FEIALKRNMPVSFEVIKESGPPHMKSFVTRVSVGEFSAEGEGNSKKLSKKRAATTVLQEL
Sbjct: 181 FEIALKRNMPVSFEVIKESGPPHMKSFVTRVSVGEFSAEGEGNSKKLSKKRAATTVLQEL 240
Query: 241 KKLPPLPVVEKPKLFFKKRPKTIVKAGPEYGQGMNPISRLAQIQQAKKEKEPDYVLLSER 300
KKLPPLPVVEKPKLFFKKRPKTIVKAGPEYGQGMNPISRLAQIQQAKKEKEPDYVLLSER
Sbjct: 241 KKLPPLPVVEKPKLFFKKRPKTIVKAGPEYGQGMNPISRLAQIQQAKKEKEPDYVLLSER 300
Query: 301 GMPRRREFVMQVKVGNEVATGTGPNKKIAKKNAAEAMLLQLGYKASTNLQDQLEKTGENK 360
GMPRRREFVMQVKVGNEVATGTGPNKKIAKKNAAEAMLLQLGYKASTNLQDQLEKTGENK
Sbjct: 301 GMPRRREFVMQVKVGNEVATGTGPNKKIAKKNAAEAMLLQLGYKASTNLQDQLEKTGENK 360
Query: 361 GWSGPKPGFPEPTNNTPKGILHLSPDVYQEMEASRHKVISGTTLGYLSPKDMNQPSSSFF 420
GWSGPKPGFPEPTNNTPKGILHLSPDVYQEMEASRHKVISGTTLGYLSPKDMNQPSSSFF
Sbjct: 361 GWSGPKPGFPEPTNNTPKGILHLSPDVYQEMEASRHKVISGTTLGYLSPKDMNQPSSSFF 420
Query: 421 SISPTSNSSATIARELLMNGTSSTAEAIGLKGSSPTPPCSPVQPSKQLEYLARIQGFQV 479
SISPTSNSSATIARELLMNGTSSTAEAIGLKGSSPTPPCSPVQPSKQLEYLARIQGFQV
Sbjct: 421 SISPTSNSSATIARELLMNGTSSTAEAIGLKGSSPTPPCSPVQPSKQLEYLARIQGFQV 479
>gi|82659087 staufen isoform b [Homo sapiens]
Length = 577
Score = 395 bits (1016), Expect = e-110
Identities = 256/523 (48%), Positives = 322/523 (61%), Gaps = 69/523 (13%)
Query: 7 MFSVQLSLGEQTWESEGSSIKKAQQAVANKAL-----TESTLP-----KPVQKP--PKSN 54
M VQ+ + + GS I Q++ ++ L T S+LP +P+Q P ++
Sbjct: 1 MSQVQVQVQNPSAALSGSQILNKNQSLLSQPLMSIPSTTSSLPSENAGRPIQNSALPSAS 60
Query: 55 VNNNPG---SITPTVELNGLAMKRGEPAIYRPLDPKPFPNYRANYNFRG-MYNQRYHCPV 110
+ + SITPTVELN L MK G+ +Y+P+DP NYN RG Y RY P
Sbjct: 61 ITSTSAAAESITPTVELNALCMKLGKKPMYKPVDPYSRMQSTYNYNMRGGAYPPRYFYPF 120
Query: 111 PK---IFYVQLTVGNNEFFGEGKTRQAARHNAAMKALQALQNEPIPERSPQNGESGKDMD 167
P ++ V+L+VG +F G+GKTRQAA+H+AA KAL+ LQNEP+PER NG
Sbjct: 121 PVPPLLYQVELSVGGQQFNGKGKTRQAAKHDAAAKALRILQNEPLPERLEVNGRES---- 176
Query: 168 DDKDANKSEISLVFEIALKRNMPVSFEVIKESGPPHMKSFVTRVSVGEFSAEGEGNSKKL 227
++++ NKSEIS VFEIALKRN+PV+FEV +ESGPPHMK+FVT+VSVGEF EGEG SKK+
Sbjct: 177 EEENLNKSEISQVFEIALKRNLPVNFEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKI 236
Query: 228 SKKRAATTVLQELKKLPPLPVVEKPKLFFKKRPKTIVK--AGPEYGQGMNPISRLAQIQQ 285
SKK AA VL+ELKKLPPLP VE+ K KK+ K IVK PEYGQG+NPISRLAQIQQ
Sbjct: 237 SKKNAAIAVLEELKKLPPLPAVERVKPRIKKKTKPIVKPQTSPEYGQGINPISRLAQIQQ 296
Query: 286 AKKEKEPDYVLLSERGMPRRREFVMQVKVGNEVATGTGPNKKIAKKNAAEAMLLQLGYKA 345
AKKEKEP+Y LL+ERG+PRRREFVMQVKVGN A GTG NKK+AK+NAAE ML LG+K
Sbjct: 297 AKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNAAENMLEILGFKV 356
Query: 346 -----STNLQDQLEKTGENKGWSGPKPGFPEP-------TNN--------------TPKG 379
+ EKT K G K F EP T+N P G
Sbjct: 357 PQAQPTKPALKSEEKTPIKKPGDGRKVTFFEPGSGDENGTSNKEDEFRMPYLSHQQLPAG 416
Query: 380 ILHLSPDVYQEMEASRHKVISGTTLGYLSPKDMNQPSSSFFSISPTSNSSATIARELLMN 439
IL + P+V Q + G + G+ KD + + + + +A IARELL
Sbjct: 417 ILPMVPEVAQAV---------GVSQGH-HTKDFTRAAPN----PAKATVTAMIARELLYG 462
Query: 440 GTSSTAEAIGLKG--SSPTPPCSPV-QPSKQLEYLARIQGFQV 479
GTS TAE I LK SS P P+ +PS+QL+YL+R+QGFQV
Sbjct: 463 GTSPTAETI-LKNNISSGHVPHGPLTRPSEQLDYLSRVQGFQV 504
>gi|82659089 staufen isoform a [Homo sapiens]
Length = 496
Score = 370 bits (951), Expect = e-102
Identities = 231/442 (52%), Positives = 283/442 (64%), Gaps = 54/442 (12%)
Query: 73 MKRGEPAIYRPLDPKPFPNYRANYNFRG-MYNQRYHCPVPK---IFYVQLTVGNNEFFGE 128
MK G+ +Y+P+DP NYN RG Y RY P P ++ V+L+VG +F G+
Sbjct: 1 MKLGKKPMYKPVDPYSRMQSTYNYNMRGGAYPPRYFYPFPVPPLLYQVELSVGGQQFNGK 60
Query: 129 GKTRQAARHNAAMKALQALQNEPIPERSPQNGESGKDMDDDKDANKSEISLVFEIALKRN 188
GKTRQAA+H+AA KAL+ LQNEP+PER NG ++++ NKSEIS VFEIALKRN
Sbjct: 61 GKTRQAAKHDAAAKALRILQNEPLPERLEVNGRES----EEENLNKSEISQVFEIALKRN 116
Query: 189 MPVSFEVIKESGPPHMKSFVTRVSVGEFSAEGEGNSKKLSKKRAATTVLQELKKLPPLPV 248
+PV+FEV +ESGPPHMK+FVT+VSVGEF EGEG SKK+SKK AA VL+ELKKLPPLP
Sbjct: 117 LPVNFEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLPPLPA 176
Query: 249 VEKPKLFFKKRPKTIVK--AGPEYGQGMNPISRLAQIQQAKKEKEPDYVLLSERGMPRRR 306
VE+ K KK+ K IVK PEYGQG+NPISRLAQIQQAKKEKEP+Y LL+ERG+PRRR
Sbjct: 177 VERVKPRIKKKTKPIVKPQTSPEYGQGINPISRLAQIQQAKKEKEPEYTLLTERGLPRRR 236
Query: 307 EFVMQVKVGNEVATGTGPNKKIAKKNAAEAMLLQLGYKA-----STNLQDQLEKTGENKG 361
EFVMQVKVGN A GTG NKK+AK+NAAE ML LG+K + EKT K
Sbjct: 237 EFVMQVKVGNHTAEGTGTNKKVAKRNAAENMLEILGFKVPQAQPTKPALKSEEKTPIKKP 296
Query: 362 WSGPKPGFPEP-------TNN--------------TPKGILHLSPDVYQEMEASRHKVIS 400
G K F EP T+N P GIL + P+V Q +
Sbjct: 297 GDGRKVTFFEPGSGDENGTSNKEDEFRMPYLSHQQLPAGILPMVPEVAQAV--------- 347
Query: 401 GTTLGYLSPKDMNQPSSSFFSISPTSNSSATIARELLMNGTSSTAEAIGLKG--SSPTPP 458
G + G+ KD + + + + +A IARELL GTS TAE I LK SS P
Sbjct: 348 GVSQGH-HTKDFTRAAPN----PAKATVTAMIARELLYGGTSPTAETI-LKNNISSGHVP 401
Query: 459 CSPV-QPSKQLEYLARIQGFQV 479
P+ +PS+QL+YL+R+QGFQV
Sbjct: 402 HGPLTRPSEQLDYLSRVQGFQV 423
Score = 67.4 bits (163), Expect = 3e-11
Identities = 70/274 (25%), Positives = 120/274 (43%), Gaps = 39/274 (14%)
Query: 7 MFSVQLSLGEQTWESEGSSIKKAQQAVANKA---LTESTLPK--PVQKPPKSNVNNNPGS 61
++ V+LS+G Q + +G + + A+ A KA L LP+ V N N
Sbjct: 45 LYQVELSVGGQQFNGKGKTRQAAKHDAAAKALRILQNEPLPERLEVNGRESEEENLNKSE 104
Query: 62 ITPTVELNGLAMKRGEPAIYRPLDPKPFPNYRANYNFRGMYNQRYHCPVPKIFYVQLTVG 121
I+ E +A+KR P + P+ K F +++VG
Sbjct: 105 ISQVFE---IALKRNLPVNFEVARESGPPHM-------------------KNFVTKVSVG 142
Query: 122 NNEFFGEGKTRQAARHNAAMKALQALQNEP----IPERSPQNGESGKDMDDDKDANK--- 174
GEGK+++ ++ NAA+ L+ L+ P + P+ + K + + + +
Sbjct: 143 EFVGEGEGKSKKISKKNAAIAVLEELKKLPPLPAVERVKPRIKKKTKPIVKPQTSPEYGQ 202
Query: 175 --SEISLVFEI-ALKRNMPVSFEVIKESGPPHMKSFVTRVSVGEFSAEGEGNSKKLSKKR 231
+ IS + +I K+ + ++ E G P + FV +V VG +AEG G +KK++K+
Sbjct: 203 GINPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRN 262
Query: 232 AATTVLQELKKLPPLPVVEKPKLFFKKRPKTIVK 265
AA +L+ L P KP L K KT +K
Sbjct: 263 AAENMLEILGFKVPQAQPTKPAL--KSEEKTPIK 294
>gi|82659085 staufen isoform a [Homo sapiens]
Length = 496
Score = 370 bits (951), Expect = e-102
Identities = 231/442 (52%), Positives = 283/442 (64%), Gaps = 54/442 (12%)
Query: 73 MKRGEPAIYRPLDPKPFPNYRANYNFRG-MYNQRYHCPVPK---IFYVQLTVGNNEFFGE 128
MK G+ +Y+P+DP NYN RG Y RY P P ++ V+L+VG +F G+
Sbjct: 1 MKLGKKPMYKPVDPYSRMQSTYNYNMRGGAYPPRYFYPFPVPPLLYQVELSVGGQQFNGK 60
Query: 129 GKTRQAARHNAAMKALQALQNEPIPERSPQNGESGKDMDDDKDANKSEISLVFEIALKRN 188
GKTRQAA+H+AA KAL+ LQNEP+PER NG ++++ NKSEIS VFEIALKRN
Sbjct: 61 GKTRQAAKHDAAAKALRILQNEPLPERLEVNGRES----EEENLNKSEISQVFEIALKRN 116
Query: 189 MPVSFEVIKESGPPHMKSFVTRVSVGEFSAEGEGNSKKLSKKRAATTVLQELKKLPPLPV 248
+PV+FEV +ESGPPHMK+FVT+VSVGEF EGEG SKK+SKK AA VL+ELKKLPPLP
Sbjct: 117 LPVNFEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLPPLPA 176
Query: 249 VEKPKLFFKKRPKTIVK--AGPEYGQGMNPISRLAQIQQAKKEKEPDYVLLSERGMPRRR 306
VE+ K KK+ K IVK PEYGQG+NPISRLAQIQQAKKEKEP+Y LL+ERG+PRRR
Sbjct: 177 VERVKPRIKKKTKPIVKPQTSPEYGQGINPISRLAQIQQAKKEKEPEYTLLTERGLPRRR 236
Query: 307 EFVMQVKVGNEVATGTGPNKKIAKKNAAEAMLLQLGYKA-----STNLQDQLEKTGENKG 361
EFVMQVKVGN A GTG NKK+AK+NAAE ML LG+K + EKT K
Sbjct: 237 EFVMQVKVGNHTAEGTGTNKKVAKRNAAENMLEILGFKVPQAQPTKPALKSEEKTPIKKP 296
Query: 362 WSGPKPGFPEP-------TNN--------------TPKGILHLSPDVYQEMEASRHKVIS 400
G K F EP T+N P GIL + P+V Q +
Sbjct: 297 GDGRKVTFFEPGSGDENGTSNKEDEFRMPYLSHQQLPAGILPMVPEVAQAV--------- 347
Query: 401 GTTLGYLSPKDMNQPSSSFFSISPTSNSSATIARELLMNGTSSTAEAIGLKG--SSPTPP 458
G + G+ KD + + + + +A IARELL GTS TAE I LK SS P
Sbjct: 348 GVSQGH-HTKDFTRAAPN----PAKATVTAMIARELLYGGTSPTAETI-LKNNISSGHVP 401
Query: 459 CSPV-QPSKQLEYLARIQGFQV 479
P+ +PS+QL+YL+R+QGFQV
Sbjct: 402 HGPLTRPSEQLDYLSRVQGFQV 423
Score = 67.4 bits (163), Expect = 3e-11
Identities = 70/274 (25%), Positives = 120/274 (43%), Gaps = 39/274 (14%)
Query: 7 MFSVQLSLGEQTWESEGSSIKKAQQAVANKA---LTESTLPK--PVQKPPKSNVNNNPGS 61
++ V+LS+G Q + +G + + A+ A KA L LP+ V N N
Sbjct: 45 LYQVELSVGGQQFNGKGKTRQAAKHDAAAKALRILQNEPLPERLEVNGRESEEENLNKSE 104
Query: 62 ITPTVELNGLAMKRGEPAIYRPLDPKPFPNYRANYNFRGMYNQRYHCPVPKIFYVQLTVG 121
I+ E +A+KR P + P+ K F +++VG
Sbjct: 105 ISQVFE---IALKRNLPVNFEVARESGPPHM-------------------KNFVTKVSVG 142
Query: 122 NNEFFGEGKTRQAARHNAAMKALQALQNEP----IPERSPQNGESGKDMDDDKDANK--- 174
GEGK+++ ++ NAA+ L+ L+ P + P+ + K + + + +
Sbjct: 143 EFVGEGEGKSKKISKKNAAIAVLEELKKLPPLPAVERVKPRIKKKTKPIVKPQTSPEYGQ 202
Query: 175 --SEISLVFEI-ALKRNMPVSFEVIKESGPPHMKSFVTRVSVGEFSAEGEGNSKKLSKKR 231
+ IS + +I K+ + ++ E G P + FV +V VG +AEG G +KK++K+
Sbjct: 203 GINPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRN 262
Query: 232 AATTVLQELKKLPPLPVVEKPKLFFKKRPKTIVK 265
AA +L+ L P KP L K KT +K
Sbjct: 263 AAENMLEILGFKVPQAQPTKPAL--KSEEKTPIK 294
>gi|82659083 staufen isoform a [Homo sapiens]
Length = 496
Score = 370 bits (951), Expect = e-102
Identities = 231/442 (52%), Positives = 283/442 (64%), Gaps = 54/442 (12%)
Query: 73 MKRGEPAIYRPLDPKPFPNYRANYNFRG-MYNQRYHCPVPK---IFYVQLTVGNNEFFGE 128
MK G+ +Y+P+DP NYN RG Y RY P P ++ V+L+VG +F G+
Sbjct: 1 MKLGKKPMYKPVDPYSRMQSTYNYNMRGGAYPPRYFYPFPVPPLLYQVELSVGGQQFNGK 60
Query: 129 GKTRQAARHNAAMKALQALQNEPIPERSPQNGESGKDMDDDKDANKSEISLVFEIALKRN 188
GKTRQAA+H+AA KAL+ LQNEP+PER NG ++++ NKSEIS VFEIALKRN
Sbjct: 61 GKTRQAAKHDAAAKALRILQNEPLPERLEVNGRES----EEENLNKSEISQVFEIALKRN 116
Query: 189 MPVSFEVIKESGPPHMKSFVTRVSVGEFSAEGEGNSKKLSKKRAATTVLQELKKLPPLPV 248
+PV+FEV +ESGPPHMK+FVT+VSVGEF EGEG SKK+SKK AA VL+ELKKLPPLP
Sbjct: 117 LPVNFEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLPPLPA 176
Query: 249 VEKPKLFFKKRPKTIVK--AGPEYGQGMNPISRLAQIQQAKKEKEPDYVLLSERGMPRRR 306
VE+ K KK+ K IVK PEYGQG+NPISRLAQIQQAKKEKEP+Y LL+ERG+PRRR
Sbjct: 177 VERVKPRIKKKTKPIVKPQTSPEYGQGINPISRLAQIQQAKKEKEPEYTLLTERGLPRRR 236
Query: 307 EFVMQVKVGNEVATGTGPNKKIAKKNAAEAMLLQLGYKA-----STNLQDQLEKTGENKG 361
EFVMQVKVGN A GTG NKK+AK+NAAE ML LG+K + EKT K
Sbjct: 237 EFVMQVKVGNHTAEGTGTNKKVAKRNAAENMLEILGFKVPQAQPTKPALKSEEKTPIKKP 296
Query: 362 WSGPKPGFPEP-------TNN--------------TPKGILHLSPDVYQEMEASRHKVIS 400
G K F EP T+N P GIL + P+V Q +
Sbjct: 297 GDGRKVTFFEPGSGDENGTSNKEDEFRMPYLSHQQLPAGILPMVPEVAQAV--------- 347
Query: 401 GTTLGYLSPKDMNQPSSSFFSISPTSNSSATIARELLMNGTSSTAEAIGLKG--SSPTPP 458
G + G+ KD + + + + +A IARELL GTS TAE I LK SS P
Sbjct: 348 GVSQGH-HTKDFTRAAPN----PAKATVTAMIARELLYGGTSPTAETI-LKNNISSGHVP 401
Query: 459 CSPV-QPSKQLEYLARIQGFQV 479
P+ +PS+QL+YL+R+QGFQV
Sbjct: 402 HGPLTRPSEQLDYLSRVQGFQV 423
Score = 67.4 bits (163), Expect = 3e-11
Identities = 70/274 (25%), Positives = 120/274 (43%), Gaps = 39/274 (14%)
Query: 7 MFSVQLSLGEQTWESEGSSIKKAQQAVANKA---LTESTLPK--PVQKPPKSNVNNNPGS 61
++ V+LS+G Q + +G + + A+ A KA L LP+ V N N
Sbjct: 45 LYQVELSVGGQQFNGKGKTRQAAKHDAAAKALRILQNEPLPERLEVNGRESEEENLNKSE 104
Query: 62 ITPTVELNGLAMKRGEPAIYRPLDPKPFPNYRANYNFRGMYNQRYHCPVPKIFYVQLTVG 121
I+ E +A+KR P + P+ K F +++VG
Sbjct: 105 ISQVFE---IALKRNLPVNFEVARESGPPHM-------------------KNFVTKVSVG 142
Query: 122 NNEFFGEGKTRQAARHNAAMKALQALQNEP----IPERSPQNGESGKDMDDDKDANK--- 174
GEGK+++ ++ NAA+ L+ L+ P + P+ + K + + + +
Sbjct: 143 EFVGEGEGKSKKISKKNAAIAVLEELKKLPPLPAVERVKPRIKKKTKPIVKPQTSPEYGQ 202
Query: 175 --SEISLVFEI-ALKRNMPVSFEVIKESGPPHMKSFVTRVSVGEFSAEGEGNSKKLSKKR 231
+ IS + +I K+ + ++ E G P + FV +V VG +AEG G +KK++K+
Sbjct: 203 GINPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRN 262
Query: 232 AATTVLQELKKLPPLPVVEKPKLFFKKRPKTIVK 265
AA +L+ L P KP L K KT +K
Sbjct: 263 AAENMLEILGFKVPQAQPTKPAL--KSEEKTPIK 294
>gi|82659091 staufen isoform c [Homo sapiens]
Length = 502
Score = 364 bits (934), Expect = e-100
Identities = 231/448 (51%), Positives = 283/448 (63%), Gaps = 60/448 (13%)
Query: 73 MKRGEPAIYRPLDPKPFPNYRANYNFRG-MYNQRYHCPVPK---IFYVQLTVGNNEFFGE 128
MK G+ +Y+P+DP NYN RG Y RY P P ++ V+L+VG +F G+
Sbjct: 1 MKLGKKPMYKPVDPYSRMQSTYNYNMRGGAYPPRYFYPFPVPPLLYQVELSVGGQQFNGK 60
Query: 129 GKTRQAARHNAAMKALQALQNEPIPERSPQNGESGKDMDDDKDANKSEISLVFEIALKRN 188
GKTRQAA+H+AA KAL+ LQNEP+PER NG ++++ NKSEIS VFEIALKRN
Sbjct: 61 GKTRQAAKHDAAAKALRILQNEPLPERLEVNGRES----EEENLNKSEISQVFEIALKRN 116
Query: 189 MPVSFE------VIKESGPPHMKSFVTRVSVGEFSAEGEGNSKKLSKKRAATTVLQELKK 242
+PV+FE V +ESGPPHMK+FVT+VSVGEF EGEG SKK+SKK AA VL+ELKK
Sbjct: 117 LPVNFESFPLKQVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKK 176
Query: 243 LPPLPVVEKPKLFFKKRPKTIVK--AGPEYGQGMNPISRLAQIQQAKKEKEPDYVLLSER 300
LPPLP VE+ K KK+ K IVK PEYGQG+NPISRLAQIQQAKKEKEP+Y LL+ER
Sbjct: 177 LPPLPAVERVKPRIKKKTKPIVKPQTSPEYGQGINPISRLAQIQQAKKEKEPEYTLLTER 236
Query: 301 GMPRRREFVMQVKVGNEVATGTGPNKKIAKKNAAEAMLLQLGYKA-----STNLQDQLEK 355
G+PRRREFVMQVKVGN A GTG NKK+AK+NAAE ML LG+K + EK
Sbjct: 237 GLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNAAENMLEILGFKVPQAQPTKPALKSEEK 296
Query: 356 TGENKGWSGPKPGFPEP-------TNN--------------TPKGILHLSPDVYQEMEAS 394
T K G K F EP T+N P GIL + P+V Q +
Sbjct: 297 TPIKKPGDGRKVTFFEPGSGDENGTSNKEDEFRMPYLSHQQLPAGILPMVPEVAQAV--- 353
Query: 395 RHKVISGTTLGYLSPKDMNQPSSSFFSISPTSNSSATIARELLMNGTSSTAEAIGLKG-- 452
G + G+ KD + + + + +A IARELL GTS TAE I LK
Sbjct: 354 ------GVSQGH-HTKDFTRAAPN----PAKATVTAMIARELLYGGTSPTAETI-LKNNI 401
Query: 453 SSPTPPCSPV-QPSKQLEYLARIQGFQV 479
SS P P+ +PS+QL+YL+R+QGFQV
Sbjct: 402 SSGHVPHGPLTRPSEQLDYLSRVQGFQV 429
Score = 69.3 bits (168), Expect = 7e-12
Identities = 71/274 (25%), Positives = 120/274 (43%), Gaps = 33/274 (12%)
Query: 7 MFSVQLSLGEQTWESEGSSIKKAQQAVANKA---LTESTLPK--PVQKPPKSNVNNNPGS 61
++ V+LS+G Q + +G + + A+ A KA L LP+ V N N
Sbjct: 45 LYQVELSVGGQQFNGKGKTRQAAKHDAAAKALRILQNEPLPERLEVNGRESEEENLNKSE 104
Query: 62 ITPTVELNGLAMKRGEPAIYRPLDPKPFPNYRANYNFRGMYNQRYHCPVPKIFYVQLTVG 121
I+ E +A+KR P + K P K F +++VG
Sbjct: 105 ISQVFE---IALKRNLPVNFESFPLKQVARESGP-------------PHMKNFVTKVSVG 148
Query: 122 NNEFFGEGKTRQAARHNAAMKALQALQNEP----IPERSPQNGESGKDMDDDKDANK--- 174
GEGK+++ ++ NAA+ L+ L+ P + P+ + K + + + +
Sbjct: 149 EFVGEGEGKSKKISKKNAAIAVLEELKKLPPLPAVERVKPRIKKKTKPIVKPQTSPEYGQ 208
Query: 175 --SEISLVFEI-ALKRNMPVSFEVIKESGPPHMKSFVTRVSVGEFSAEGEGNSKKLSKKR 231
+ IS + +I K+ + ++ E G P + FV +V VG +AEG G +KK++K+
Sbjct: 209 GINPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRN 268
Query: 232 AATTVLQELKKLPPLPVVEKPKLFFKKRPKTIVK 265
AA +L+ L P KP L K KT +K
Sbjct: 269 AAENMLEILGFKVPQAQPTKPAL--KSEEKTPIK 300
>gi|19743838 TAR RNA binding protein 2 isoform b [Homo sapiens]
Length = 345
Score = 79.3 bits (194), Expect = 7e-15
Identities = 57/198 (28%), Positives = 93/198 (46%), Gaps = 31/198 (15%)
Query: 174 KSEISLVFEIALKRNMPVSFEVIKESGPPHMKSFVTRVSVGEFSAEGEGNSKKLSKKRAA 233
K+ ISL+ E + ++++K G H +F RV+VG+ S G+G SKK +K +AA
Sbjct: 8 KTPISLLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTVGDTSCTGQGPSKKAAKHKAA 67
Query: 234 TTVLQELK--------------------KLPP-LPVVEK-------PKLFFKKRPKTIVK 265
L+ LK LP +PV P + + P ++
Sbjct: 68 EVALKHLKGGSMLEPALEDSSSFSPLDSSLPEDIPVFTAAAAATPVPSVVLTRSPPMELQ 127
Query: 266 --AGPEYGQGMNPISRLAQIQQAKKEKEPDYVLLSERGMPRRREFVMQVKVGNEVATGTG 323
P+ + NP+ L ++ K + P+Y + E G R+EF M +V + G+G
Sbjct: 128 PPVSPQQSE-CNPVGALQELVVQKGWRLPEYTVTQESGPAHRKEFTMTCRVERFIEIGSG 186
Query: 324 PNKKIAKKNAAEAMLLQL 341
+KK+AK+NAA MLL++
Sbjct: 187 TSKKLAKRNAAAKMLLRV 204
Score = 52.8 bits (125), Expect = 7e-07
Identities = 42/168 (25%), Positives = 70/168 (41%), Gaps = 37/168 (22%)
Query: 114 FYVQLTVGNNEFFGEGKTRQAARHNAAMKALQALQNEPIPERSPQNGESGKDMDDDKDAN 173
F ++TVG+ G+G +++AA+H AA AL+ L+ + E + ++ S +D +
Sbjct: 41 FTFRVTVGDTSCTGQGPSKKAAKHKAAEVALKHLKGGSMLEPALEDSSSFSPLDSSLPED 100
Query: 174 ------KSEISLVFEIALKRNMPVSFE-------------------------------VI 196
+ + V + L R+ P+ + V
Sbjct: 101 IPVFTAAAAATPVPSVVLTRSPPMELQPPVSPQQSECNPVGALQELVVQKGWRLPEYTVT 160
Query: 197 KESGPPHMKSFVTRVSVGEFSAEGEGNSKKLSKKRAATTVLQELKKLP 244
+ESGP H K F V F G G SKKL+K+ AA +L + +P
Sbjct: 161 QESGPAHRKEFTMTCRVERFIEIGSGTSKKLAKRNAAAKMLLRVHTVP 208
Score = 47.4 bits (111), Expect = 3e-05
Identities = 33/82 (40%), Positives = 40/82 (48%), Gaps = 3/82 (3%)
Query: 273 GMNPISRLAQIQQAKKEKEPDYVLLSERGMPRRREFVMQVKVGNEVATGTGPNKKIAKKN 332
G PIS L Q + K P Y LL G + F +V VG+ TG GP+KK AK
Sbjct: 7 GKTPIS-LLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTVGDTSCTGQGPSKKAAKHK 65
Query: 333 AAEAMLLQLGYKASTNLQDQLE 354
AAE L L K + L+ LE
Sbjct: 66 AAEVALKHL--KGGSMLEPALE 85
>gi|19743840 TAR RNA binding protein 2 isoform a [Homo sapiens]
Length = 366
Score = 79.3 bits (194), Expect = 7e-15
Identities = 57/198 (28%), Positives = 93/198 (46%), Gaps = 31/198 (15%)
Query: 174 KSEISLVFEIALKRNMPVSFEVIKESGPPHMKSFVTRVSVGEFSAEGEGNSKKLSKKRAA 233
K+ ISL+ E + ++++K G H +F RV+VG+ S G+G SKK +K +AA
Sbjct: 29 KTPISLLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTVGDTSCTGQGPSKKAAKHKAA 88
Query: 234 TTVLQELK--------------------KLPP-LPVVEK-------PKLFFKKRPKTIVK 265
L+ LK LP +PV P + + P ++
Sbjct: 89 EVALKHLKGGSMLEPALEDSSSFSPLDSSLPEDIPVFTAAAAATPVPSVVLTRSPPMELQ 148
Query: 266 --AGPEYGQGMNPISRLAQIQQAKKEKEPDYVLLSERGMPRRREFVMQVKVGNEVATGTG 323
P+ + NP+ L ++ K + P+Y + E G R+EF M +V + G+G
Sbjct: 149 PPVSPQQSE-CNPVGALQELVVQKGWRLPEYTVTQESGPAHRKEFTMTCRVERFIEIGSG 207
Query: 324 PNKKIAKKNAAEAMLLQL 341
+KK+AK+NAA MLL++
Sbjct: 208 TSKKLAKRNAAAKMLLRV 225
Score = 52.8 bits (125), Expect = 7e-07
Identities = 42/168 (25%), Positives = 70/168 (41%), Gaps = 37/168 (22%)
Query: 114 FYVQLTVGNNEFFGEGKTRQAARHNAAMKALQALQNEPIPERSPQNGESGKDMDDDKDAN 173
F ++TVG+ G+G +++AA+H AA AL+ L+ + E + ++ S +D +
Sbjct: 62 FTFRVTVGDTSCTGQGPSKKAAKHKAAEVALKHLKGGSMLEPALEDSSSFSPLDSSLPED 121
Query: 174 ------KSEISLVFEIALKRNMPVSFE-------------------------------VI 196
+ + V + L R+ P+ + V
Sbjct: 122 IPVFTAAAAATPVPSVVLTRSPPMELQPPVSPQQSECNPVGALQELVVQKGWRLPEYTVT 181
Query: 197 KESGPPHMKSFVTRVSVGEFSAEGEGNSKKLSKKRAATTVLQELKKLP 244
+ESGP H K F V F G G SKKL+K+ AA +L + +P
Sbjct: 182 QESGPAHRKEFTMTCRVERFIEIGSGTSKKLAKRNAAAKMLLRVHTVP 229
Score = 47.4 bits (111), Expect = 3e-05
Identities = 33/82 (40%), Positives = 40/82 (48%), Gaps = 3/82 (3%)
Query: 273 GMNPISRLAQIQQAKKEKEPDYVLLSERGMPRRREFVMQVKVGNEVATGTGPNKKIAKKN 332
G PIS L Q + K P Y LL G + F +V VG+ TG GP+KK AK
Sbjct: 28 GKTPIS-LLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTVGDTSCTGQGPSKKAAKHK 86
Query: 333 AAEAMLLQLGYKASTNLQDQLE 354
AAE L L K + L+ LE
Sbjct: 87 AAEVALKHL--KGGSMLEPALE 106
>gi|85068512 TAR RNA binding protein 2 isoform b [Homo sapiens]
Length = 345
Score = 79.3 bits (194), Expect = 7e-15
Identities = 57/198 (28%), Positives = 93/198 (46%), Gaps = 31/198 (15%)
Query: 174 KSEISLVFEIALKRNMPVSFEVIKESGPPHMKSFVTRVSVGEFSAEGEGNSKKLSKKRAA 233
K+ ISL+ E + ++++K G H +F RV+VG+ S G+G SKK +K +AA
Sbjct: 8 KTPISLLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTVGDTSCTGQGPSKKAAKHKAA 67
Query: 234 TTVLQELK--------------------KLPP-LPVVEK-------PKLFFKKRPKTIVK 265
L+ LK LP +PV P + + P ++
Sbjct: 68 EVALKHLKGGSMLEPALEDSSSFSPLDSSLPEDIPVFTAAAAATPVPSVVLTRSPPMELQ 127
Query: 266 --AGPEYGQGMNPISRLAQIQQAKKEKEPDYVLLSERGMPRRREFVMQVKVGNEVATGTG 323
P+ + NP+ L ++ K + P+Y + E G R+EF M +V + G+G
Sbjct: 128 PPVSPQQSE-CNPVGALQELVVQKGWRLPEYTVTQESGPAHRKEFTMTCRVERFIEIGSG 186
Query: 324 PNKKIAKKNAAEAMLLQL 341
+KK+AK+NAA MLL++
Sbjct: 187 TSKKLAKRNAAAKMLLRV 204
Score = 52.8 bits (125), Expect = 7e-07
Identities = 42/168 (25%), Positives = 70/168 (41%), Gaps = 37/168 (22%)
Query: 114 FYVQLTVGNNEFFGEGKTRQAARHNAAMKALQALQNEPIPERSPQNGESGKDMDDDKDAN 173
F ++TVG+ G+G +++AA+H AA AL+ L+ + E + ++ S +D +
Sbjct: 41 FTFRVTVGDTSCTGQGPSKKAAKHKAAEVALKHLKGGSMLEPALEDSSSFSPLDSSLPED 100
Query: 174 ------KSEISLVFEIALKRNMPVSFE-------------------------------VI 196
+ + V + L R+ P+ + V
Sbjct: 101 IPVFTAAAAATPVPSVVLTRSPPMELQPPVSPQQSECNPVGALQELVVQKGWRLPEYTVT 160
Query: 197 KESGPPHMKSFVTRVSVGEFSAEGEGNSKKLSKKRAATTVLQELKKLP 244
+ESGP H K F V F G G SKKL+K+ AA +L + +P
Sbjct: 161 QESGPAHRKEFTMTCRVERFIEIGSGTSKKLAKRNAAAKMLLRVHTVP 208
Score = 47.4 bits (111), Expect = 3e-05
Identities = 33/82 (40%), Positives = 40/82 (48%), Gaps = 3/82 (3%)
Query: 273 GMNPISRLAQIQQAKKEKEPDYVLLSERGMPRRREFVMQVKVGNEVATGTGPNKKIAKKN 332
G PIS L Q + K P Y LL G + F +V VG+ TG GP+KK AK
Sbjct: 7 GKTPIS-LLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTVGDTSCTGQGPSKKAAKHK 65
Query: 333 AAEAMLLQLGYKASTNLQDQLE 354
AAE L L K + L+ LE
Sbjct: 66 AAEVALKHL--KGGSMLEPALE 85
>gi|213417919 protein kinase, interferon-inducible double stranded
RNA dependent activator isoform 3 [Homo sapiens]
Length = 288
Score = 78.6 bits (192), Expect = 1e-14
Identities = 71/268 (26%), Positives = 121/268 (45%), Gaps = 26/268 (9%)
Query: 174 KSEISLVFEIALK-RNMPVSFEVIKESGPPHMKSFVTRVSVGEFSAEGEGNSKKLSKKRA 232
K+ I ++ E +K +N+PV +E + H+ +F RV+VG+ + GEG SKKL+K RA
Sbjct: 8 KTPIQVLHEYGMKTKNIPV-YECERSDVQIHVPTFTFRVTVGDITCTGEGTSKKLAKHRA 66
Query: 233 ATTVLQELKK------LPPLPVVEKPKLFFKKRPKTIVKAGPEYGQGMNPISRLAQIQQA 286
A + LK P P++ P K+PK +NPI L ++
Sbjct: 67 AEAAINILKANASICFAVPDPLMPDP----SKQPK----------NQLNPIGSLQELAIH 112
Query: 287 KKEKEPDYVLLSERGMPRRREFVMQVKVGNEVATGTGPNKKIAKKNAAEAMLLQLGYKAS 346
+ P+Y L E G +RE+ ++ + + TG G +KK AK+NAAE L + +
Sbjct: 113 HGWRLPEYTLSQEGGPAHKREYTTICRLESFMETGKGASKKQAKRNAAEKFLAKFSNISP 172
Query: 347 TNLQDQLEKTGENKG--WSGPKPGFPEPTNNTPKGILHLSPDVYQEMEASRHKVISGTTL 404
N G + G W + E N + +L + Y ++ + K G +
Sbjct: 173 ENHISLTNVVGHSLGCTWHSLRNSPGEKINLLKRSLLSIPNTDYIQLLSEIAKE-QGFNI 231
Query: 405 GYLSPKDMNQPSSSFFSISPTSNSSATI 432
YL +++ + + ++ S S T+
Sbjct: 232 TYLDIDELS-ANGQYQCLAELSTSPITV 258
Score = 49.3 bits (116), Expect = 8e-06
Identities = 36/145 (24%), Positives = 63/145 (43%), Gaps = 26/145 (17%)
Query: 114 FYVQLTVGNNEFFGEGKTRQAARHNAAMKALQALQNE------------PIPERSPQNGE 161
F ++TVG+ GEG +++ A+H AA A+ L+ P P + P+N
Sbjct: 41 FTFRVTVGDITCTGEGTSKKLAKHRAAEAAINILKANASICFAVPDPLMPDPSKQPKN-- 98
Query: 162 SGKDMDDDKDANKSEISLVFEIALKRNMPV-SFEVIKESGPPHMKSFVTRVSVGEFSAEG 220
+ I + E+A+ + + + +E GP H + + T + F G
Sbjct: 99 -----------QLNPIGSLQELAIHHGWRLPEYTLSQEGGPAHKREYTTICRLESFMETG 147
Query: 221 EGNSKKLSKKRAATTVLQELKKLPP 245
+G SKK +K+ AA L + + P
Sbjct: 148 KGASKKQAKRNAAEKFLAKFSNISP 172
>gi|213417911 protein kinase, interferon-inducible double stranded
RNA dependent activator isoform 2 [Homo sapiens]
Length = 302
Score = 78.6 bits (192), Expect = 1e-14
Identities = 71/268 (26%), Positives = 121/268 (45%), Gaps = 26/268 (9%)
Query: 174 KSEISLVFEIALK-RNMPVSFEVIKESGPPHMKSFVTRVSVGEFSAEGEGNSKKLSKKRA 232
K+ I ++ E +K +N+PV +E + H+ +F RV+VG+ + GEG SKKL+K RA
Sbjct: 22 KTPIQVLHEYGMKTKNIPV-YECERSDVQIHVPTFTFRVTVGDITCTGEGTSKKLAKHRA 80
Query: 233 ATTVLQELKK------LPPLPVVEKPKLFFKKRPKTIVKAGPEYGQGMNPISRLAQIQQA 286
A + LK P P++ P K+PK +NPI L ++
Sbjct: 81 AEAAINILKANASICFAVPDPLMPDP----SKQPK----------NQLNPIGSLQELAIH 126
Query: 287 KKEKEPDYVLLSERGMPRRREFVMQVKVGNEVATGTGPNKKIAKKNAAEAMLLQLGYKAS 346
+ P+Y L E G +RE+ ++ + + TG G +KK AK+NAAE L + +
Sbjct: 127 HGWRLPEYTLSQEGGPAHKREYTTICRLESFMETGKGASKKQAKRNAAEKFLAKFSNISP 186
Query: 347 TNLQDQLEKTGENKG--WSGPKPGFPEPTNNTPKGILHLSPDVYQEMEASRHKVISGTTL 404
N G + G W + E N + +L + Y ++ + K G +
Sbjct: 187 ENHISLTNVVGHSLGCTWHSLRNSPGEKINLLKRSLLSIPNTDYIQLLSEIAKE-QGFNI 245
Query: 405 GYLSPKDMNQPSSSFFSISPTSNSSATI 432
YL +++ + + ++ S S T+
Sbjct: 246 TYLDIDELS-ANGQYQCLAELSTSPITV 272
Score = 49.3 bits (116), Expect = 8e-06
Identities = 36/145 (24%), Positives = 63/145 (43%), Gaps = 26/145 (17%)
Query: 114 FYVQLTVGNNEFFGEGKTRQAARHNAAMKALQALQNE------------PIPERSPQNGE 161
F ++TVG+ GEG +++ A+H AA A+ L+ P P + P+N
Sbjct: 55 FTFRVTVGDITCTGEGTSKKLAKHRAAEAAINILKANASICFAVPDPLMPDPSKQPKN-- 112
Query: 162 SGKDMDDDKDANKSEISLVFEIALKRNMPV-SFEVIKESGPPHMKSFVTRVSVGEFSAEG 220
+ I + E+A+ + + + +E GP H + + T + F G
Sbjct: 113 -----------QLNPIGSLQELAIHHGWRLPEYTLSQEGGPAHKREYTTICRLESFMETG 161
Query: 221 EGNSKKLSKKRAATTVLQELKKLPP 245
+G SKK +K+ AA L + + P
Sbjct: 162 KGASKKQAKRNAAEKFLAKFSNISP 186
>gi|4505581 protein kinase, interferon-inducible double stranded RNA
dependent activator isoform 1 [Homo sapiens]
Length = 313
Score = 78.6 bits (192), Expect = 1e-14
Identities = 71/268 (26%), Positives = 121/268 (45%), Gaps = 26/268 (9%)
Query: 174 KSEISLVFEIALK-RNMPVSFEVIKESGPPHMKSFVTRVSVGEFSAEGEGNSKKLSKKRA 232
K+ I ++ E +K +N+PV +E + H+ +F RV+VG+ + GEG SKKL+K RA
Sbjct: 33 KTPIQVLHEYGMKTKNIPV-YECERSDVQIHVPTFTFRVTVGDITCTGEGTSKKLAKHRA 91
Query: 233 ATTVLQELKK------LPPLPVVEKPKLFFKKRPKTIVKAGPEYGQGMNPISRLAQIQQA 286
A + LK P P++ P K+PK +NPI L ++
Sbjct: 92 AEAAINILKANASICFAVPDPLMPDP----SKQPK----------NQLNPIGSLQELAIH 137
Query: 287 KKEKEPDYVLLSERGMPRRREFVMQVKVGNEVATGTGPNKKIAKKNAAEAMLLQLGYKAS 346
+ P+Y L E G +RE+ ++ + + TG G +KK AK+NAAE L + +
Sbjct: 138 HGWRLPEYTLSQEGGPAHKREYTTICRLESFMETGKGASKKQAKRNAAEKFLAKFSNISP 197
Query: 347 TNLQDQLEKTGENKG--WSGPKPGFPEPTNNTPKGILHLSPDVYQEMEASRHKVISGTTL 404
N G + G W + E N + +L + Y ++ + K G +
Sbjct: 198 ENHISLTNVVGHSLGCTWHSLRNSPGEKINLLKRSLLSIPNTDYIQLLSEIAKE-QGFNI 256
Query: 405 GYLSPKDMNQPSSSFFSISPTSNSSATI 432
YL +++ + + ++ S S T+
Sbjct: 257 TYLDIDELS-ANGQYQCLAELSTSPITV 283
Score = 49.3 bits (116), Expect = 8e-06
Identities = 36/145 (24%), Positives = 63/145 (43%), Gaps = 26/145 (17%)
Query: 114 FYVQLTVGNNEFFGEGKTRQAARHNAAMKALQALQNE------------PIPERSPQNGE 161
F ++TVG+ GEG +++ A+H AA A+ L+ P P + P+N
Sbjct: 66 FTFRVTVGDITCTGEGTSKKLAKHRAAEAAINILKANASICFAVPDPLMPDPSKQPKN-- 123
Query: 162 SGKDMDDDKDANKSEISLVFEIALKRNMPV-SFEVIKESGPPHMKSFVTRVSVGEFSAEG 220
+ I + E+A+ + + + +E GP H + + T + F G
Sbjct: 124 -----------QLNPIGSLQELAIHHGWRLPEYTLSQEGGPAHKREYTTICRLESFMETG 172
Query: 221 EGNSKKLSKKRAATTVLQELKKLPP 245
+G SKK +K+ AA L + + P
Sbjct: 173 KGASKKQAKRNAAEKFLAKFSNISP 197
>gi|212549555 interleukin enhancer binding factor 3 isoform e [Homo
sapiens]
Length = 706
Score = 65.9 bits (159), Expect = 8e-11
Identities = 69/260 (26%), Positives = 101/260 (38%), Gaps = 46/260 (17%)
Query: 151 PIPERSPQNGESGKDMDDDKDANKSEISLVFEIALKRNM---PVSFEVIKESGPPHMKSF 207
P+ E + S K K K+E ++ N + ++++ ++GP H F
Sbjct: 373 PMEEDGEEKSPSKKKKKIQKKEEKAEPPQAMNALMRLNQLKPGLQYKLVSQTGPVHAPIF 432
Query: 208 VTRVSVGEFSAEGEGNSKKLSKKRAATTVLQEL-------------------------KK 242
V V S E G SKK +K A VLQ++
Sbjct: 433 TMSVEVDGNSFEASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSKGEDSAEETEAKPAV 492
Query: 243 LPPLPVVEK---PKLFFKK--RPKTIVKAGPEYGQ-GMNPISRLAQIQQAKKEKEPDYVL 296
+ P PVVE P F + + + GP + G NP+ L + ++ K Y L
Sbjct: 493 VAPAPVVEAVSTPSAAFPSDATAENVKQQGPILTKHGKNPVMELNEKRRGLK-----YEL 547
Query: 297 LSERGMPRRREFVMQVKVGNEVATGTGPNKKIAKKNAAEAMLLQLGYKASTNLQDQLEKT 356
+SE G + FVM+V+V + G G NKK+AK AA A L +L L +K
Sbjct: 548 ISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAALEKLFPDTPLALDANKKKR 607
Query: 357 GENKGWSGPK-------PGF 369
GPK PGF
Sbjct: 608 APVPVRGGPKFAAKPHNPGF 627
>gi|212549553 interleukin enhancer binding factor 3 isoform d [Homo
sapiens]
Length = 898
Score = 65.9 bits (159), Expect = 8e-11
Identities = 69/260 (26%), Positives = 101/260 (38%), Gaps = 46/260 (17%)
Query: 151 PIPERSPQNGESGKDMDDDKDANKSEISLVFEIALKRNM---PVSFEVIKESGPPHMKSF 207
P+ E + S K K K+E ++ N + ++++ ++GP H F
Sbjct: 373 PMEEDGEEKSPSKKKKKIQKKEEKAEPPQAMNALMRLNQLKPGLQYKLVSQTGPVHAPIF 432
Query: 208 VTRVSVGEFSAEGEGNSKKLSKKRAATTVLQEL-------------------------KK 242
V V S E G SKK +K A VLQ++
Sbjct: 433 TMSVEVDGNSFEASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSKGEDSAEETEAKPAV 492
Query: 243 LPPLPVVEK---PKLFFKK--RPKTIVKAGPEYGQ-GMNPISRLAQIQQAKKEKEPDYVL 296
+ P PVVE P F + + + GP + G NP+ L + ++ K Y L
Sbjct: 493 VAPAPVVEAVSTPSAAFPSDATAENVKQQGPILTKHGKNPVMELNEKRRGLK-----YEL 547
Query: 297 LSERGMPRRREFVMQVKVGNEVATGTGPNKKIAKKNAAEAMLLQLGYKASTNLQDQLEKT 356
+SE G + FVM+V+V + G G NKK+AK AA A L +L L +K
Sbjct: 548 ISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAALEKLFPDTPLALDANKKKR 607
Query: 357 GENKGWSGPK-------PGF 369
GPK PGF
Sbjct: 608 APVPVRGGPKFAAKPHNPGF 627
>gi|24234756 interleukin enhancer binding factor 3 isoform c [Homo
sapiens]
Length = 690
Score = 65.1 bits (157), Expect = 1e-10
Identities = 68/256 (26%), Positives = 98/256 (38%), Gaps = 42/256 (16%)
Query: 151 PIPERSPQNGESGKDMDDDKDANKSEISLVFEIALKRNM---PVSFEVIKESGPPHMKSF 207
P+ E + S K K K+E ++ N + ++++ ++GP H F
Sbjct: 373 PMEEDGEEKSPSKKKKKIQKKEEKAEPPQAMNALMRLNQLKPGLQYKLVSQTGPVHAPIF 432
Query: 208 VTRVSVGEFSAEGEGNSKKLSKKRAATTVLQEL-------------------------KK 242
V V S E G SKK +K A VLQ++
Sbjct: 433 TMSVEVDGNSFEASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSKGEDSAEETEAKPAV 492
Query: 243 LPPLPVVEKPKLFFKKRPK-TIVKAGPEYGQ-GMNPISRLAQIQQAKKEKEPDYVLLSER 300
+ P PVVE P + GP + G NP+ L + ++ K Y L+SE
Sbjct: 493 VAPAPVVEAVSTPSAAFPSDATAEQGPILTKHGKNPVMELNEKRRGLK-----YELISET 547
Query: 301 GMPRRREFVMQVKVGNEVATGTGPNKKIAKKNAAEAMLLQLGYKASTNLQDQLEKTGENK 360
G + FVM+V+V + G G NKK+AK AA A L +L L +K
Sbjct: 548 GGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAALEKLFPDTPLALDANKKKRAPVP 607
Query: 361 GWSGPK-------PGF 369
GPK PGF
Sbjct: 608 VRGGPKFAAKPHNPGF 623
>gi|24234753 interleukin enhancer binding factor 3 isoform b [Homo
sapiens]
Length = 702
Score = 65.1 bits (157), Expect = 1e-10
Identities = 68/256 (26%), Positives = 98/256 (38%), Gaps = 42/256 (16%)
Query: 151 PIPERSPQNGESGKDMDDDKDANKSEISLVFEIALKRNM---PVSFEVIKESGPPHMKSF 207
P+ E + S K K K+E ++ N + ++++ ++GP H F
Sbjct: 373 PMEEDGEEKSPSKKKKKIQKKEEKAEPPQAMNALMRLNQLKPGLQYKLVSQTGPVHAPIF 432
Query: 208 VTRVSVGEFSAEGEGNSKKLSKKRAATTVLQEL-------------------------KK 242
V V S E G SKK +K A VLQ++
Sbjct: 433 TMSVEVDGNSFEASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSKGEDSAEETEAKPAV 492
Query: 243 LPPLPVVEKPKLFFKKRPK-TIVKAGPEYGQ-GMNPISRLAQIQQAKKEKEPDYVLLSER 300
+ P PVVE P + GP + G NP+ L + ++ K Y L+SE
Sbjct: 493 VAPAPVVEAVSTPSAAFPSDATAEQGPILTKHGKNPVMELNEKRRGLK-----YELISET 547
Query: 301 GMPRRREFVMQVKVGNEVATGTGPNKKIAKKNAAEAMLLQLGYKASTNLQDQLEKTGENK 360
G + FVM+V+V + G G NKK+AK AA A L +L L +K
Sbjct: 548 GGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAALEKLFPDTPLALDANKKKRAPVP 607
Query: 361 GWSGPK-------PGF 369
GPK PGF
Sbjct: 608 VRGGPKFAAKPHNPGF 623
>gi|24234750 interleukin enhancer binding factor 3 isoform a [Homo
sapiens]
Length = 894
Score = 65.1 bits (157), Expect = 1e-10
Identities = 68/256 (26%), Positives = 98/256 (38%), Gaps = 42/256 (16%)
Query: 151 PIPERSPQNGESGKDMDDDKDANKSEISLVFEIALKRNM---PVSFEVIKESGPPHMKSF 207
P+ E + S K K K+E ++ N + ++++ ++GP H F
Sbjct: 373 PMEEDGEEKSPSKKKKKIQKKEEKAEPPQAMNALMRLNQLKPGLQYKLVSQTGPVHAPIF 432
Query: 208 VTRVSVGEFSAEGEGNSKKLSKKRAATTVLQEL-------------------------KK 242
V V S E G SKK +K A VLQ++
Sbjct: 433 TMSVEVDGNSFEASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSKGEDSAEETEAKPAV 492
Query: 243 LPPLPVVEKPKLFFKKRPK-TIVKAGPEYGQ-GMNPISRLAQIQQAKKEKEPDYVLLSER 300
+ P PVVE P + GP + G NP+ L + ++ K Y L+SE
Sbjct: 493 VAPAPVVEAVSTPSAAFPSDATAEQGPILTKHGKNPVMELNEKRRGLK-----YELISET 547
Query: 301 GMPRRREFVMQVKVGNEVATGTGPNKKIAKKNAAEAMLLQLGYKASTNLQDQLEKTGENK 360
G + FVM+V+V + G G NKK+AK AA A L +L L +K
Sbjct: 548 GGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAALEKLFPDTPLALDANKKKRAPVP 607
Query: 361 GWSGPK-------PGF 369
GPK PGF
Sbjct: 608 VRGGPKFAAKPHNPGF 623
>gi|70167032 adenosine deaminase, RNA-specific isoform c [Homo
sapiens]
Length = 1181
Score = 57.8 bits (138), Expect = 2e-08
Identities = 55/199 (27%), Positives = 93/199 (46%), Gaps = 15/199 (7%)
Query: 174 KSEISLVFEIALKRNMPVSFEVIKESGPPHMKSFVTRVSV-GEFSAEGEGNSKKLSKKRA 232
K+ IS + E A + F +I++SGPPH F +V + G E SKK++K+ A
Sbjct: 502 KNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDA 561
Query: 233 A----TTVLQELKKLPPLPVVEKPKLFFKK------RPKTIVKAGPEYGQGMNPISRLAQ 282
A T +L+E K E +K +T + + G +P++ L +
Sbjct: 562 AMKAMTILLEEAKAKDSGKSEESSHYSTEKESEKTAESQTPTPSATSFFSGKSPVTTLLE 621
Query: 283 IQQAKKEKEPDYVLLSERGMPRRREFVMQVKVGNEV-ATGTGPNKKIAKKNAAEAMLLQL 341
K ++ LLS+ G +F V VG + + + P+KK+AK+ AAE + L
Sbjct: 622 CMH-KLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKAL 680
Query: 342 GYKASTNL--QDQLEKTGE 358
+A+ ++ +Q+ K GE
Sbjct: 681 HGEATNSMASDNQVRKIGE 699
Score = 47.0 bits (110), Expect = 4e-05
Identities = 57/245 (23%), Positives = 103/245 (42%), Gaps = 29/245 (11%)
Query: 114 FYVQLTVGNNEFF-GEGKTRQAARHNAAMKALQALQNEPIPERSPQNGESGK---DMDDD 169
F Q+ + EF E +++ A+ +AAMKA+ L E + S ++ ES + + +
Sbjct: 535 FKFQVVINGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDSGKSEESSHYSTEKESE 594
Query: 170 KDAN--------------KSEISLVFEIALKRNMPVSFEVIKESGPPHMKSFVTRVSVG- 214
K A KS ++ + E K F ++ + GP H F V+VG
Sbjct: 595 KTAESQTPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGA 654
Query: 215 EFSAEGEGNSKKLSKKRAATTVLQELKKLPPLPVVEKPKLFFKKRPKTIVKAGPEYGQGM 274
+ SKK++K+ AA ++ L + ++ ++ +V+
Sbjct: 655 QTFPSVSAPSKKVAKQMAAEEAMKALHGEATNSMASDNQV---RKIGELVRY-----LNT 706
Query: 275 NPISRLAQIQQAKKEKEPDYVLLSERGMPRRREFVMQVKVGNE-VATGTGPNKKIAKKNA 333
NP+ L + ++ ++ L+ + G P +FV Q KVG +KK K+ A
Sbjct: 707 NPVGGLLEYARS-HGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEA 765
Query: 334 AEAML 338
A+A L
Sbjct: 766 ADAAL 770
Score = 41.2 bits (95), Expect = 0.002
Identities = 30/111 (27%), Positives = 53/111 (47%), Gaps = 2/111 (1%)
Query: 131 TRQAARHNAAMKALQALQNEPIPERSPQNGESGKDMDDDKDANKSEISLVFEIALKRNMP 190
+++ A+ AA +A++AL E + N + K + + N + + + E A
Sbjct: 664 SKKVAKQMAAEEAMKALHGEATNSMASDN-QVRKIGELVRYLNTNPVGGLLEYARSHGFA 722
Query: 191 VSFEVIKESGPPHMKSFVTRVSV-GEFSAEGEGNSKKLSKKRAATTVLQEL 240
F+++ +SGPPH FV + V G + +SKK K+ AA L+ L
Sbjct: 723 AEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVL 773
>gi|21361745 spermatid perinuclear RNA binding protein [Homo
sapiens]
Length = 672
Score = 57.8 bits (138), Expect = 2e-08
Identities = 70/283 (24%), Positives = 110/283 (38%), Gaps = 66/283 (23%)
Query: 132 RQAARHNAAMKALQALQNEPIPERSPQNGESGKDMD------------------DDKDAN 173
+ A R +A + + L+ +P+P P S D DDKD N
Sbjct: 311 QHALRLSAFGQIYKVLEMDPLPSSKPFQKYSWSVTDKEGAGSSALKRPFEDGLGDDKDPN 370
Query: 174 K-----------SEISLVFEIALKRNM---PVSFEVIKESGPPHMKSFVTRVSVGEFSAE 219
K S+ + ++ N + ++++ +SGP H F V V + E
Sbjct: 371 KKMKRNLRKILDSKAIDLMNALMRLNQIRPGLQYKLLSQSGPVHAPVFTMSVDVDGTTYE 430
Query: 220 GEGNSKKLSKKRAATTVLQEL-------KKLPPLPVVEKPKLFFKKRPKT---------- 262
G SKK +K A VLQ + + + EK K +
Sbjct: 431 ASGPSKKTAKLHVAVKVLQAMGYPTGFDADIECMSSDEKSDNESKNETVSSNSSNNTGNS 490
Query: 263 ---------IVKAGPEY-GQGMNPISRLAQIQQAKKEKEPDYVLLSERGMPRRREFVMQV 312
+ GP G NP+ L + ++ K Y L+SE G + FVM+V
Sbjct: 491 TTETSSTLEVRTQGPILTASGKNPVMELNEKRRGLK-----YELISETGGSHDKRFVMEV 545
Query: 313 KVGNEVATGTGPNKKIAKKNAAEAMLLQL--GYKASTNLQDQL 353
+V + G GPNKK+AK +AA A L +L G A+ N + ++
Sbjct: 546 EVDGQKFRGAGPNKKVAKASAALAALEKLFSGPNAANNKKKKI 588
Score = 42.7 bits (99), Expect = 7e-04
Identities = 45/179 (25%), Positives = 71/179 (39%), Gaps = 35/179 (19%)
Query: 107 HCPVPKIFYVQLTVGNNEFFGEGKTRQAARHNAAMKALQAL------------------- 147
H PV F + + V + G +++ A+ + A+K LQA+
Sbjct: 414 HAPV---FTMSVDVDGTTYEASGPSKKTAKLHVAVKVLQAMGYPTGFDADIECMSSDEKS 470
Query: 148 ----QNEPIPERSPQN-GESGKDMDDDKDANKSEISL-------VFEIALKRNMPVSFEV 195
+NE + S N G S + + L V E+ KR + +E+
Sbjct: 471 DNESKNETVSSNSSNNTGNSTTETSSTLEVRTQGPILTASGKNPVMELNEKRR-GLKYEL 529
Query: 196 IKESGPPHMKSFVTRVSVGEFSAEGEGNSKKLSKKRAATTVLQELKKLPPLPVVEKPKL 254
I E+G H K FV V V G G +KK++K AA L++L P +K K+
Sbjct: 530 ISETGGSHDKRFVMEVEVDGQKFRGAGPNKKVAKASAALAALEKLFSGPNAANNKKKKI 588
>gi|70167113 adenosine deaminase, RNA-specific isoform d [Homo
sapiens]
Length = 931
Score = 55.1 bits (131), Expect = 1e-07
Identities = 52/196 (26%), Positives = 89/196 (45%), Gaps = 13/196 (6%)
Query: 174 KSEISLVFEIALKRNMPVSFEVIKESGPPHMKSFVTRVSV-GEFSAEGEGNSKKLSKKRA 232
K+ IS + E A + F +I++SGPPH F +V + G E SKK++K+ A
Sbjct: 207 KNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDA 266
Query: 233 A----TTVLQELKKLPPLPVVEKPKLFFKK------RPKTIVKAGPEYGQGMNPISRLAQ 282
A T +L+E K E +K +T + + G +P++ L +
Sbjct: 267 AMKAMTILLEEAKAKDSGKSEESSHYSTEKESEKTAESQTPTPSATSFFSGKSPVTTLLE 326
Query: 283 IQQAKKEKEPDYVLLSERGMPRRREFVMQVKVGNEV-ATGTGPNKKIAKKNAAEAMLLQL 341
K ++ LLS+ G +F V VG + + + P+KK+AK+ AAE + L
Sbjct: 327 CMH-KLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKAL 385
Query: 342 GYKASTNLQDQLEKTG 357
+A+ ++ + G
Sbjct: 386 HGEATNSMASDNQPEG 401
Score = 49.3 bits (116), Expect = 8e-06
Identities = 61/256 (23%), Positives = 102/256 (39%), Gaps = 32/256 (12%)
Query: 114 FYVQLTVGNNEFF-GEGKTRQAARHNAAMKALQALQNEPIPERSPQNGESGK---DMDDD 169
F Q+ + EF E +++ A+ +AAMKA+ L E + S ++ ES + + +
Sbjct: 240 FKFQVVINGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDSGKSEESSHYSTEKESE 299
Query: 170 KDAN--------------KSEISLVFEIALKRNMPVSFEVIKESGPPHMKSFVTRVSVG- 214
K A KS ++ + E K F ++ + GP H F V+VG
Sbjct: 300 KTAESQTPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGA 359
Query: 215 EFSAEGEGNSKKLSKKRAATTVLQEL----------KKLPPLPVVEKPKLFFKKRPKTIV 264
+ SKK++K+ AA ++ L P + E P +
Sbjct: 360 QTFPSVSAPSKKVAKQMAAEEAMKALHGEATNSMASDNQPEGMISESLDNLESMMPNKVR 419
Query: 265 KAGPEYGQ-GMNPISRLAQIQQAKKEKEPDYVLLSERGMPRRREFVMQVKVGNE-VATGT 322
K G NP+ L + ++ ++ L+ + G P +FV Q KVG
Sbjct: 420 KIGELVRYLNTNPVGGLLEYARS-HGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVC 478
Query: 323 GPNKKIAKKNAAEAML 338
+KK K+ AA+A L
Sbjct: 479 AHSKKQGKQEAADAAL 494
Score = 37.7 bits (86), Expect = 0.023
Identities = 31/129 (24%), Positives = 55/129 (42%), Gaps = 19/129 (14%)
Query: 131 TRQAARHNAAMKALQALQNEPIPERSPQNGESG---KDMDDDKDA--------------- 172
+++ A+ AA +A++AL E + N G + +D+ +
Sbjct: 369 SKKVAKQMAAEEAMKALHGEATNSMASDNQPEGMISESLDNLESMMPNKVRKIGELVRYL 428
Query: 173 NKSEISLVFEIALKRNMPVSFEVIKESGPPHMKSFVTRVSV-GEFSAEGEGNSKKLSKKR 231
N + + + E A F+++ +SGPPH FV + V G + +SKK K+
Sbjct: 429 NTNPVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQE 488
Query: 232 AATTVLQEL 240
AA L+ L
Sbjct: 489 AADAALRVL 497
>gi|70166944 adenosine deaminase, RNA-specific isoform b [Homo
sapiens]
Length = 1200
Score = 55.1 bits (131), Expect = 1e-07
Identities = 52/196 (26%), Positives = 89/196 (45%), Gaps = 13/196 (6%)
Query: 174 KSEISLVFEIALKRNMPVSFEVIKESGPPHMKSFVTRVSV-GEFSAEGEGNSKKLSKKRA 232
K+ IS + E A + F +I++SGPPH F +V + G E SKK++K+ A
Sbjct: 502 KNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDA 561
Query: 233 A----TTVLQELKKLPPLPVVEKPKLFFKK------RPKTIVKAGPEYGQGMNPISRLAQ 282
A T +L+E K E +K +T + + G +P++ L +
Sbjct: 562 AMKAMTILLEEAKAKDSGKSEESSHYSTEKESEKTAESQTPTPSATSFFSGKSPVTTLLE 621
Query: 283 IQQAKKEKEPDYVLLSERGMPRRREFVMQVKVGNEV-ATGTGPNKKIAKKNAAEAMLLQL 341
K ++ LLS+ G +F V VG + + + P+KK+AK+ AAE + L
Sbjct: 622 CMH-KLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKAL 680
Query: 342 GYKASTNLQDQLEKTG 357
+A+ ++ + G
Sbjct: 681 HGEATNSMASDNQPEG 696
Score = 49.3 bits (116), Expect = 8e-06
Identities = 61/256 (23%), Positives = 102/256 (39%), Gaps = 32/256 (12%)
Query: 114 FYVQLTVGNNEFF-GEGKTRQAARHNAAMKALQALQNEPIPERSPQNGESGK---DMDDD 169
F Q+ + EF E +++ A+ +AAMKA+ L E + S ++ ES + + +
Sbjct: 535 FKFQVVINGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDSGKSEESSHYSTEKESE 594
Query: 170 KDAN--------------KSEISLVFEIALKRNMPVSFEVIKESGPPHMKSFVTRVSVG- 214
K A KS ++ + E K F ++ + GP H F V+VG
Sbjct: 595 KTAESQTPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGA 654
Query: 215 EFSAEGEGNSKKLSKKRAATTVLQEL----------KKLPPLPVVEKPKLFFKKRPKTIV 264
+ SKK++K+ AA ++ L P + E P +
Sbjct: 655 QTFPSVSAPSKKVAKQMAAEEAMKALHGEATNSMASDNQPEGMISESLDNLESMMPNKVR 714
Query: 265 KAGPEYGQ-GMNPISRLAQIQQAKKEKEPDYVLLSERGMPRRREFVMQVKVGNE-VATGT 322
K G NP+ L + ++ ++ L+ + G P +FV Q KVG
Sbjct: 715 KIGELVRYLNTNPVGGLLEYARS-HGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVC 773
Query: 323 GPNKKIAKKNAAEAML 338
+KK K+ AA+A L
Sbjct: 774 AHSKKQGKQEAADAAL 789
Score = 37.7 bits (86), Expect = 0.023
Identities = 31/129 (24%), Positives = 55/129 (42%), Gaps = 19/129 (14%)
Query: 131 TRQAARHNAAMKALQALQNEPIPERSPQNGESG---KDMDDDKDA--------------- 172
+++ A+ AA +A++AL E + N G + +D+ +
Sbjct: 664 SKKVAKQMAAEEAMKALHGEATNSMASDNQPEGMISESLDNLESMMPNKVRKIGELVRYL 723
Query: 173 NKSEISLVFEIALKRNMPVSFEVIKESGPPHMKSFVTRVSV-GEFSAEGEGNSKKLSKKR 231
N + + + E A F+++ +SGPPH FV + V G + +SKK K+
Sbjct: 724 NTNPVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQE 783
Query: 232 AATTVLQEL 240
AA L+ L
Sbjct: 784 AADAALRVL 792
>gi|70166852 adenosine deaminase, RNA-specific isoform a [Homo
sapiens]
Length = 1226
Score = 55.1 bits (131), Expect = 1e-07
Identities = 52/196 (26%), Positives = 89/196 (45%), Gaps = 13/196 (6%)
Query: 174 KSEISLVFEIALKRNMPVSFEVIKESGPPHMKSFVTRVSV-GEFSAEGEGNSKKLSKKRA 232
K+ IS + E A + F +I++SGPPH F +V + G E SKK++K+ A
Sbjct: 502 KNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDA 561
Query: 233 A----TTVLQELKKLPPLPVVEKPKLFFKK------RPKTIVKAGPEYGQGMNPISRLAQ 282
A T +L+E K E +K +T + + G +P++ L +
Sbjct: 562 AMKAMTILLEEAKAKDSGKSEESSHYSTEKESEKTAESQTPTPSATSFFSGKSPVTTLLE 621
Query: 283 IQQAKKEKEPDYVLLSERGMPRRREFVMQVKVGNEV-ATGTGPNKKIAKKNAAEAMLLQL 341
K ++ LLS+ G +F V VG + + + P+KK+AK+ AAE + L
Sbjct: 622 CMH-KLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKAL 680
Query: 342 GYKASTNLQDQLEKTG 357
+A+ ++ + G
Sbjct: 681 HGEATNSMASDNQPEG 696
Score = 49.3 bits (116), Expect = 8e-06
Identities = 61/256 (23%), Positives = 102/256 (39%), Gaps = 32/256 (12%)
Query: 114 FYVQLTVGNNEFF-GEGKTRQAARHNAAMKALQALQNEPIPERSPQNGESGK---DMDDD 169
F Q+ + EF E +++ A+ +AAMKA+ L E + S ++ ES + + +
Sbjct: 535 FKFQVVINGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDSGKSEESSHYSTEKESE 594
Query: 170 KDAN--------------KSEISLVFEIALKRNMPVSFEVIKESGPPHMKSFVTRVSVG- 214
K A KS ++ + E K F ++ + GP H F V+VG
Sbjct: 595 KTAESQTPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGA 654
Query: 215 EFSAEGEGNSKKLSKKRAATTVLQEL----------KKLPPLPVVEKPKLFFKKRPKTIV 264
+ SKK++K+ AA ++ L P + E P +
Sbjct: 655 QTFPSVSAPSKKVAKQMAAEEAMKALHGEATNSMASDNQPEGMISESLDNLESMMPNKVR 714
Query: 265 KAGPEYGQ-GMNPISRLAQIQQAKKEKEPDYVLLSERGMPRRREFVMQVKVGNE-VATGT 322
K G NP+ L + ++ ++ L+ + G P +FV Q KVG
Sbjct: 715 KIGELVRYLNTNPVGGLLEYARS-HGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVC 773
Query: 323 GPNKKIAKKNAAEAML 338
+KK K+ AA+A L
Sbjct: 774 AHSKKQGKQEAADAAL 789
Score = 37.7 bits (86), Expect = 0.023
Identities = 31/129 (24%), Positives = 55/129 (42%), Gaps = 19/129 (14%)
Query: 131 TRQAARHNAAMKALQALQNEPIPERSPQNGESG---KDMDDDKDA--------------- 172
+++ A+ AA +A++AL E + N G + +D+ +
Sbjct: 664 SKKVAKQMAAEEAMKALHGEATNSMASDNQPEGMISESLDNLESMMPNKVRKIGELVRYL 723
Query: 173 NKSEISLVFEIALKRNMPVSFEVIKESGPPHMKSFVTRVSV-GEFSAEGEGNSKKLSKKR 231
N + + + E A F+++ +SGPPH FV + V G + +SKK K+
Sbjct: 724 NTNPVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQE 783
Query: 232 AATTVLQEL 240
AA L+ L
Sbjct: 784 AADAALRVL 792
>gi|237681091 RNA-specific adenosine deaminase B1 isoform 7 [Homo
sapiens]
Length = 674
Score = 52.8 bits (125), Expect = 7e-07
Identities = 57/232 (24%), Positives = 88/232 (37%), Gaps = 43/232 (18%)
Query: 107 HCPVPKIFYVQLTVGNNEFFGEGKTRQAARHNAAMKALQALQNEPIPERSPQNGESGKDM 166
H P +F + + V F G G T++ A+ +AA KAL++ P S + G+ +
Sbjct: 105 HAP---LFVMSVEVNGQVFEGSGPTKKKAKLHAAEKALRSFVQ--FPNASEAHLAMGRTL 159
Query: 167 DDDKDANKSEISLVFEIALKRNMPVSFEVIKESGPPHMKSFVTRVSVGEFSAEGEGNSKK 226
+ D + + FE ++ PP S G+ S G+
Sbjct: 160 SVNTDFTSDQADF------PDTLFNGFETPDKAEPPFYVG-----SNGDDSFSSSGDLSL 208
Query: 227 LSKKRAATTVLQELKKLPPLPVVEKPKLFFKKRPKTIVKAGPEYGQGMNPISRLAQIQQA 286
+ A+ L LPP P G NP+ L +++
Sbjct: 209 SASPVPASLAQPPLPVLPPFPPPS----------------------GKNPVMILNELRPG 246
Query: 287 KKEKEPDYVLLSERGMPRRREFVMQVKVGNEVATGTGPNKKIAKKNAAEAML 338
K Y LSE G + FVM V V + G+G NKK+AK AA++ L
Sbjct: 247 LK-----YDFLSESGESHAKSFVMSVVVDGQFFEGSGRNKKLAKARAAQSAL 293
Score = 43.5 bits (101), Expect = 4e-04
Identities = 34/86 (39%), Positives = 44/86 (51%), Gaps = 10/86 (11%)
Query: 253 KLFFKKRPKTIVKAGPEYGQGMNPISRLAQIQQAKKEKEPDYVLLSERGMPRRREFVMQV 312
K KKR KT GP + P + L Q+ + K + Y LLS+ G FVM V
Sbjct: 64 KYRLKKRRKT---PGP-----VLPKNALMQLNEIKPGLQ--YTLLSQTGPVHAPLFVMSV 113
Query: 313 KVGNEVATGTGPNKKIAKKNAAEAML 338
+V +V G+GP KK AK +AAE L
Sbjct: 114 EVNGQVFEGSGPTKKKAKLHAAEKAL 139
Score = 41.2 bits (95), Expect = 0.002
Identities = 22/53 (41%), Positives = 30/53 (56%)
Query: 191 VSFEVIKESGPPHMKSFVTRVSVGEFSAEGEGNSKKLSKKRAATTVLQELKKL 243
+ ++ + ESG H KSFV V V EG G +KKL+K RAA + L + L
Sbjct: 247 LKYDFLSESGESHAKSFVMSVVVDGQFFEGSGRNKKLAKARAAQSALAAIFNL 299
Score = 33.9 bits (76), Expect = 0.34
Identities = 17/54 (31%), Positives = 27/54 (50%)
Query: 191 VSFEVIKESGPPHMKSFVTRVSVGEFSAEGEGNSKKLSKKRAATTVLQELKKLP 244
+ + ++ ++GP H FV V V EG G +KK +K AA L+ + P
Sbjct: 93 LQYTLLSQTGPVHAPLFVMSVEVNGQVFEGSGPTKKKAKLHAAEKALRSFVQFP 146
>gi|7669479 RNA-specific adenosine deaminase B1 isoform 3 [Homo
sapiens]
Length = 714
Score = 52.8 bits (125), Expect = 7e-07
Identities = 57/232 (24%), Positives = 88/232 (37%), Gaps = 43/232 (18%)
Query: 107 HCPVPKIFYVQLTVGNNEFFGEGKTRQAARHNAAMKALQALQNEPIPERSPQNGESGKDM 166
H P +F + + V F G G T++ A+ +AA KAL++ P S + G+ +
Sbjct: 105 HAP---LFVMSVEVNGQVFEGSGPTKKKAKLHAAEKALRSFVQ--FPNASEAHLAMGRTL 159
Query: 167 DDDKDANKSEISLVFEIALKRNMPVSFEVIKESGPPHMKSFVTRVSVGEFSAEGEGNSKK 226
+ D + + FE ++ PP S G+ S G+
Sbjct: 160 SVNTDFTSDQADF------PDTLFNGFETPDKAEPPFYVG-----SNGDDSFSSSGDLSL 208
Query: 227 LSKKRAATTVLQELKKLPPLPVVEKPKLFFKKRPKTIVKAGPEYGQGMNPISRLAQIQQA 286
+ A+ L LPP P G NP+ L +++
Sbjct: 209 SASPVPASLAQPPLPVLPPFPPPS----------------------GKNPVMILNELRPG 246
Query: 287 KKEKEPDYVLLSERGMPRRREFVMQVKVGNEVATGTGPNKKIAKKNAAEAML 338
K Y LSE G + FVM V V + G+G NKK+AK AA++ L
Sbjct: 247 LK-----YDFLSESGESHAKSFVMSVVVDGQFFEGSGRNKKLAKARAAQSAL 293
Score = 43.5 bits (101), Expect = 4e-04
Identities = 34/86 (39%), Positives = 44/86 (51%), Gaps = 10/86 (11%)
Query: 253 KLFFKKRPKTIVKAGPEYGQGMNPISRLAQIQQAKKEKEPDYVLLSERGMPRRREFVMQV 312
K KKR KT GP + P + L Q+ + K + Y LLS+ G FVM V
Sbjct: 64 KYRLKKRRKT---PGP-----VLPKNALMQLNEIKPGLQ--YTLLSQTGPVHAPLFVMSV 113
Query: 313 KVGNEVATGTGPNKKIAKKNAAEAML 338
+V +V G+GP KK AK +AAE L
Sbjct: 114 EVNGQVFEGSGPTKKKAKLHAAEKAL 139
Score = 41.2 bits (95), Expect = 0.002
Identities = 22/53 (41%), Positives = 30/53 (56%)
Query: 191 VSFEVIKESGPPHMKSFVTRVSVGEFSAEGEGNSKKLSKKRAATTVLQELKKL 243
+ ++ + ESG H KSFV V V EG G +KKL+K RAA + L + L
Sbjct: 247 LKYDFLSESGESHAKSFVMSVVVDGQFFEGSGRNKKLAKARAAQSALAAIFNL 299
Score = 33.9 bits (76), Expect = 0.34
Identities = 17/54 (31%), Positives = 27/54 (50%)
Query: 191 VSFEVIKESGPPHMKSFVTRVSVGEFSAEGEGNSKKLSKKRAATTVLQELKKLP 244
+ + ++ ++GP H FV V V EG G +KK +K AA L+ + P
Sbjct: 93 LQYTLLSQTGPVHAPLFVMSVEVNGQVFEGSGPTKKKAKLHAAEKALRSFVQFP 146
>gi|7669477 RNA-specific adenosine deaminase B1 isoform 2 [Homo
sapiens]
Length = 741
Score = 52.8 bits (125), Expect = 7e-07
Identities = 57/232 (24%), Positives = 88/232 (37%), Gaps = 43/232 (18%)
Query: 107 HCPVPKIFYVQLTVGNNEFFGEGKTRQAARHNAAMKALQALQNEPIPERSPQNGESGKDM 166
H P +F + + V F G G T++ A+ +AA KAL++ P S + G+ +
Sbjct: 105 HAP---LFVMSVEVNGQVFEGSGPTKKKAKLHAAEKALRSFVQ--FPNASEAHLAMGRTL 159
Query: 167 DDDKDANKSEISLVFEIALKRNMPVSFEVIKESGPPHMKSFVTRVSVGEFSAEGEGNSKK 226
+ D + + FE ++ PP S G+ S G+
Sbjct: 160 SVNTDFTSDQADF------PDTLFNGFETPDKAEPPFYVG-----SNGDDSFSSSGDLSL 208
Query: 227 LSKKRAATTVLQELKKLPPLPVVEKPKLFFKKRPKTIVKAGPEYGQGMNPISRLAQIQQA 286
+ A+ L LPP P G NP+ L +++
Sbjct: 209 SASPVPASLAQPPLPVLPPFPPPS----------------------GKNPVMILNELRPG 246
Query: 287 KKEKEPDYVLLSERGMPRRREFVMQVKVGNEVATGTGPNKKIAKKNAAEAML 338
K Y LSE G + FVM V V + G+G NKK+AK AA++ L
Sbjct: 247 LK-----YDFLSESGESHAKSFVMSVVVDGQFFEGSGRNKKLAKARAAQSAL 293
Score = 43.5 bits (101), Expect = 4e-04
Identities = 34/86 (39%), Positives = 44/86 (51%), Gaps = 10/86 (11%)
Query: 253 KLFFKKRPKTIVKAGPEYGQGMNPISRLAQIQQAKKEKEPDYVLLSERGMPRRREFVMQV 312
K KKR KT GP + P + L Q+ + K + Y LLS+ G FVM V
Sbjct: 64 KYRLKKRRKT---PGP-----VLPKNALMQLNEIKPGLQ--YTLLSQTGPVHAPLFVMSV 113
Query: 313 KVGNEVATGTGPNKKIAKKNAAEAML 338
+V +V G+GP KK AK +AAE L
Sbjct: 114 EVNGQVFEGSGPTKKKAKLHAAEKAL 139
Score = 41.2 bits (95), Expect = 0.002
Identities = 22/53 (41%), Positives = 30/53 (56%)
Query: 191 VSFEVIKESGPPHMKSFVTRVSVGEFSAEGEGNSKKLSKKRAATTVLQELKKL 243
+ ++ + ESG H KSFV V V EG G +KKL+K RAA + L + L
Sbjct: 247 LKYDFLSESGESHAKSFVMSVVVDGQFFEGSGRNKKLAKARAAQSALAAIFNL 299
Score = 33.9 bits (76), Expect = 0.34
Identities = 17/54 (31%), Positives = 27/54 (50%)
Query: 191 VSFEVIKESGPPHMKSFVTRVSVGEFSAEGEGNSKKLSKKRAATTVLQELKKLP 244
+ + ++ ++GP H FV V V EG G +KK +K AA L+ + P
Sbjct: 93 LQYTLLSQTGPVHAPLFVMSVEVNGQVFEGSGPTKKKAKLHAAEKALRSFVQFP 146
>gi|4501919 RNA-specific adenosine deaminase B1 isoform 1 [Homo
sapiens]
Length = 701
Score = 52.8 bits (125), Expect = 7e-07
Identities = 57/232 (24%), Positives = 88/232 (37%), Gaps = 43/232 (18%)
Query: 107 HCPVPKIFYVQLTVGNNEFFGEGKTRQAARHNAAMKALQALQNEPIPERSPQNGESGKDM 166
H P +F + + V F G G T++ A+ +AA KAL++ P S + G+ +
Sbjct: 105 HAP---LFVMSVEVNGQVFEGSGPTKKKAKLHAAEKALRSFVQ--FPNASEAHLAMGRTL 159
Query: 167 DDDKDANKSEISLVFEIALKRNMPVSFEVIKESGPPHMKSFVTRVSVGEFSAEGEGNSKK 226
+ D + + FE ++ PP S G+ S G+
Sbjct: 160 SVNTDFTSDQADF------PDTLFNGFETPDKAEPPFYVG-----SNGDDSFSSSGDLSL 208
Query: 227 LSKKRAATTVLQELKKLPPLPVVEKPKLFFKKRPKTIVKAGPEYGQGMNPISRLAQIQQA 286
+ A+ L LPP P G NP+ L +++
Sbjct: 209 SASPVPASLAQPPLPVLPPFPPPS----------------------GKNPVMILNELRPG 246
Query: 287 KKEKEPDYVLLSERGMPRRREFVMQVKVGNEVATGTGPNKKIAKKNAAEAML 338
K Y LSE G + FVM V V + G+G NKK+AK AA++ L
Sbjct: 247 LK-----YDFLSESGESHAKSFVMSVVVDGQFFEGSGRNKKLAKARAAQSAL 293
Score = 43.5 bits (101), Expect = 4e-04
Identities = 34/86 (39%), Positives = 44/86 (51%), Gaps = 10/86 (11%)
Query: 253 KLFFKKRPKTIVKAGPEYGQGMNPISRLAQIQQAKKEKEPDYVLLSERGMPRRREFVMQV 312
K KKR KT GP + P + L Q+ + K + Y LLS+ G FVM V
Sbjct: 64 KYRLKKRRKT---PGP-----VLPKNALMQLNEIKPGLQ--YTLLSQTGPVHAPLFVMSV 113
Query: 313 KVGNEVATGTGPNKKIAKKNAAEAML 338
+V +V G+GP KK AK +AAE L
Sbjct: 114 EVNGQVFEGSGPTKKKAKLHAAEKAL 139
Score = 41.2 bits (95), Expect = 0.002
Identities = 22/53 (41%), Positives = 30/53 (56%)
Query: 191 VSFEVIKESGPPHMKSFVTRVSVGEFSAEGEGNSKKLSKKRAATTVLQELKKL 243
+ ++ + ESG H KSFV V V EG G +KKL+K RAA + L + L
Sbjct: 247 LKYDFLSESGESHAKSFVMSVVVDGQFFEGSGRNKKLAKARAAQSALAAIFNL 299
Score = 33.9 bits (76), Expect = 0.34
Identities = 17/54 (31%), Positives = 27/54 (50%)
Query: 191 VSFEVIKESGPPHMKSFVTRVSVGEFSAEGEGNSKKLSKKRAATTVLQELKKLP 244
+ + ++ ++GP H FV V V EG G +KK +K AA L+ + P
Sbjct: 93 LQYTLLSQTGPVHAPLFVMSVEVNGQVFEGSGPTKKKAKLHAAEKALRSFVQFP 146
>gi|208431829 eukaryotic translation initiation factor 2-alpha
kinase 2 isoform b [Homo sapiens]
Length = 510
Score = 51.2 bits (121), Expect = 2e-06
Identities = 48/158 (30%), Positives = 74/158 (46%), Gaps = 14/158 (8%)
Query: 186 KRNMPVSFEVIKESGPPHMKSFVTRVSV-GEFSAEGEGNSKKLSKKRAATTVLQELKKLP 244
K+ + + ++ + SGPPH + F +V + G EGEG SKK +K AA ++ L K
Sbjct: 20 KQGVVLKYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSKKEAKNAAAKLAVEILNK-- 77
Query: 245 PLPVVEKPKLFFKKRPKTIVKAGPEYGQGMNPISRLAQIQQAKKEKEPDYVLLSERGMPR 304
EK + T G G + I+R+AQ KK +Y + G+
Sbjct: 78 -----EKKAVSPLLLTTTNSSEGLSMGNYIGLINRIAQ----KKRLTVNYEQCAS-GVHG 127
Query: 305 RREFVMQVKVG-NEVATGTGPNKKIAKKNAAEAMLLQL 341
F + K+G E + GTG K+ AK+ AA+ LQ+
Sbjct: 128 PEGFHYKCKMGQKEYSIGTGSTKQEAKQLAAKLAYLQI 165
>gi|208431827 eukaryotic translation initiation factor 2-alpha
kinase 2 isoform a [Homo sapiens]
Length = 551
Score = 51.2 bits (121), Expect = 2e-06
Identities = 48/158 (30%), Positives = 74/158 (46%), Gaps = 14/158 (8%)
Query: 186 KRNMPVSFEVIKESGPPHMKSFVTRVSV-GEFSAEGEGNSKKLSKKRAATTVLQELKKLP 244
K+ + + ++ + SGPPH + F +V + G EGEG SKK +K AA ++ L K
Sbjct: 20 KQGVVLKYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSKKEAKNAAAKLAVEILNK-- 77
Query: 245 PLPVVEKPKLFFKKRPKTIVKAGPEYGQGMNPISRLAQIQQAKKEKEPDYVLLSERGMPR 304
EK + T G G + I+R+AQ KK +Y + G+
Sbjct: 78 -----EKKAVSPLLLTTTNSSEGLSMGNYIGLINRIAQ----KKRLTVNYEQCAS-GVHG 127
Query: 305 RREFVMQVKVG-NEVATGTGPNKKIAKKNAAEAMLLQL 341
F + K+G E + GTG K+ AK+ AA+ LQ+
Sbjct: 128 PEGFHYKCKMGQKEYSIGTGSTKQEAKQLAAKLAYLQI 165
>gi|4506103 eukaryotic translation initiation factor 2-alpha kinase
2 isoform a [Homo sapiens]
Length = 551
Score = 51.2 bits (121), Expect = 2e-06
Identities = 48/158 (30%), Positives = 74/158 (46%), Gaps = 14/158 (8%)
Query: 186 KRNMPVSFEVIKESGPPHMKSFVTRVSV-GEFSAEGEGNSKKLSKKRAATTVLQELKKLP 244
K+ + + ++ + SGPPH + F +V + G EGEG SKK +K AA ++ L K
Sbjct: 20 KQGVVLKYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSKKEAKNAAAKLAVEILNK-- 77
Query: 245 PLPVVEKPKLFFKKRPKTIVKAGPEYGQGMNPISRLAQIQQAKKEKEPDYVLLSERGMPR 304
EK + T G G + I+R+AQ KK +Y + G+
Sbjct: 78 -----EKKAVSPLLLTTTNSSEGLSMGNYIGLINRIAQ----KKRLTVNYEQCAS-GVHG 127
Query: 305 RREFVMQVKVG-NEVATGTGPNKKIAKKNAAEAMLLQL 341
F + K+G E + GTG K+ AK+ AA+ LQ+
Sbjct: 128 PEGFHYKCKMGQKEYSIGTGSTKQEAKQLAAKLAYLQI 165
>gi|8922077 adenosine deaminase, RNA-specific, B2 [Homo sapiens]
Length = 739
Score = 49.3 bits (116), Expect = 8e-06
Identities = 49/200 (24%), Positives = 74/200 (37%), Gaps = 49/200 (24%)
Query: 191 VSFEVIKESGPPHMKSFVTRVSVGEFSAEGEGNSKKLSKKRAATTVLQELKKLP------ 244
+ + + ++GP H F V V + EG G +KK +K RAA L+ + P
Sbjct: 140 LQYRTVSQTGPVHAPVFAVAVEVNGLTFEGTGPTKKKAKMRAAELALRSFVQFPNACQAH 199
Query: 245 ------PLP-------VVEKPKLFFKK-------------RPKTIVKAGPEYGQ------ 272
P P + P F++ RP YG+
Sbjct: 200 LAMGGGPGPGTDFTSDQADFPDTLFQEFEPPAPRPGLAGGRPGDAALLSAAYGRRRLLCR 259
Query: 273 GMNPISRLAQIQQAKKEKEP-----------DYVLLSERGMPRRREFVMQVKVGNEVATG 321
++ + A E+ P YV L+E R R FVM V V G
Sbjct: 260 ALDLVGPTPATPAAPGERNPVVLLNRLRAGLRYVCLAEPAERRARSFVMAVSVDGRTFEG 319
Query: 322 TGPNKKIAKKNAAEAMLLQL 341
+G +KK+A+ AA+A L +L
Sbjct: 320 SGRSKKLARGQAAQAALQEL 339
Score = 32.0 bits (71), Expect = 1.3
Identities = 21/63 (33%), Positives = 30/63 (47%), Gaps = 2/63 (3%)
Query: 276 PISRLAQIQQAKKEKEPDYVLLSERGMPRRREFVMQVKVGNEVATGTGPNKKIAKKNAAE 335
P + L Q+ + + + Y +S+ G F + V+V GTGP KK AK AAE
Sbjct: 126 PKNALVQLHELRPGLQ--YRTVSQTGPVHAPVFAVAVEVNGLTFEGTGPTKKKAKMRAAE 183
Query: 336 AML 338
L
Sbjct: 184 LAL 186
Score = 30.4 bits (67), Expect = 3.7
Identities = 15/44 (34%), Positives = 25/44 (56%)
Query: 114 FYVQLTVGNNEFFGEGKTRQAARHNAAMKALQALQNEPIPERSP 157
F + ++V F G G++++ AR AA ALQ L + +P +P
Sbjct: 306 FVMAVSVDGRTFEGSGRSKKLARGQAAQAALQELFDIQMPGHAP 349
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.129 0.365
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,160,940
Number of Sequences: 37866
Number of extensions: 1002714
Number of successful extensions: 3190
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 34
Number of HSP's successfully gapped in prelim test: 47
Number of HSP's that attempted gapping in prelim test: 2966
Number of HSP's gapped (non-prelim): 155
length of query: 479
length of database: 18,247,518
effective HSP length: 106
effective length of query: 373
effective length of database: 14,233,722
effective search space: 5309178306
effective search space used: 5309178306
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.