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Search of human proteins with 7657554
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7657554 dickkopf-like 1 precursor [Homo sapiens]
(242 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7657554 dickkopf-like 1 precursor [Homo sapiens] 481 e-136
gi|66346689 dickkopf homolog 3 precursor [Homo sapiens] 58 8e-09
gi|40548393 dickkopf homolog 3 precursor [Homo sapiens] 58 8e-09
gi|40548389 dickkopf homolog 3 precursor [Homo sapiens] 58 8e-09
gi|28558969 mediator complex subunit 23 isoform b [Homo sapiens] 30 1.9
gi|28558971 mediator complex subunit 23 isoform a [Homo sapiens] 30 1.9
gi|45505173 B cell RAG associated protein [Homo sapiens] 30 1.9
gi|71274148 pleckstrin homology domain containing, family G (wit... 29 3.2
gi|94536856 coiled-coil domain containing 106 [Homo sapiens] 29 3.2
gi|47578101 selenoprotein N, 1 isoform 2 precursor [Homo sapiens] 29 4.2
gi|47578099 selenoprotein N, 1 isoform 1 precursor [Homo sapiens] 29 4.2
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 29 4.2
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 29 4.2
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 29 4.2
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 29 4.2
gi|148762940 DVL-binding protein DAPLE [Homo sapiens] 29 4.2
gi|153281202 neuropeptide W preproprotein [Homo sapiens] 29 4.2
gi|203097724 cadherin-like 29 [Homo sapiens] 28 5.5
gi|119709832 low density lipoprotein receptor-related protein 5 ... 28 7.2
gi|46255064 synaptotagmin-like 2 isoform d [Homo sapiens] 28 7.2
gi|46255062 synaptotagmin-like 2 isoform c [Homo sapiens] 28 7.2
gi|11321565 matrilin 3 precursor [Homo sapiens] 28 7.2
gi|223468602 t-complex 10-like 2 [Homo sapiens] 28 9.4
gi|110624774 mannose receptor, C type 2 [Homo sapiens] 28 9.4
gi|105553088 t-complex 10 [Homo sapiens] 28 9.4
>gi|7657554 dickkopf-like 1 precursor [Homo sapiens]
Length = 242
Score = 481 bits (1239), Expect = e-136
Identities = 242/242 (100%), Positives = 242/242 (100%)
Query: 1 MGEASPPAPARRHLLVLLLLLSTLVIPSAAAPIHDADAQESSLGLTGLQSLLQGFSRLFL 60
MGEASPPAPARRHLLVLLLLLSTLVIPSAAAPIHDADAQESSLGLTGLQSLLQGFSRLFL
Sbjct: 1 MGEASPPAPARRHLLVLLLLLSTLVIPSAAAPIHDADAQESSLGLTGLQSLLQGFSRLFL 60
Query: 61 KGNLLRGIDSLFSAPMDFRGLPGNYHKEENQEHQLGNNTLSSHLQIDKMTDNKTGEVLIS 120
KGNLLRGIDSLFSAPMDFRGLPGNYHKEENQEHQLGNNTLSSHLQIDKMTDNKTGEVLIS
Sbjct: 61 KGNLLRGIDSLFSAPMDFRGLPGNYHKEENQEHQLGNNTLSSHLQIDKMTDNKTGEVLIS 120
Query: 121 ENVVASIQPAEGSFEGDLKVPRMEEKEALVPIQKATDSFHTELHPRVAFWIIKLPRRRSH 180
ENVVASIQPAEGSFEGDLKVPRMEEKEALVPIQKATDSFHTELHPRVAFWIIKLPRRRSH
Sbjct: 121 ENVVASIQPAEGSFEGDLKVPRMEEKEALVPIQKATDSFHTELHPRVAFWIIKLPRRRSH 180
Query: 181 QDALEGGHWLSEKRHRLQAIRDGLRKGTHKDVLEEGTESSSHSRLSPRKTHLLYILRPSR 240
QDALEGGHWLSEKRHRLQAIRDGLRKGTHKDVLEEGTESSSHSRLSPRKTHLLYILRPSR
Sbjct: 181 QDALEGGHWLSEKRHRLQAIRDGLRKGTHKDVLEEGTESSSHSRLSPRKTHLLYILRPSR 240
Query: 241 QL 242
QL
Sbjct: 241 QL 242
>gi|66346689 dickkopf homolog 3 precursor [Homo sapiens]
Length = 350
Score = 57.8 bits (138), Expect = 8e-09
Identities = 24/60 (40%), Positives = 41/60 (68%)
Query: 73 SAPMDFRGLPGNYHKEENQEHQLGNNTLSSHLQIDKMTDNKTGEVLISENVVASIQPAEG 132
S+ ++ LP +YH E N + ++GNNT+ H +I K+T+N+TG+++ SE V+ S+ EG
Sbjct: 82 SSEVNLANLPPSYHNETNTDTKVGNNTIHVHREIHKITNNQTGQMVFSETVITSVGDEEG 141
>gi|40548393 dickkopf homolog 3 precursor [Homo sapiens]
Length = 350
Score = 57.8 bits (138), Expect = 8e-09
Identities = 24/60 (40%), Positives = 41/60 (68%)
Query: 73 SAPMDFRGLPGNYHKEENQEHQLGNNTLSSHLQIDKMTDNKTGEVLISENVVASIQPAEG 132
S+ ++ LP +YH E N + ++GNNT+ H +I K+T+N+TG+++ SE V+ S+ EG
Sbjct: 82 SSEVNLANLPPSYHNETNTDTKVGNNTIHVHREIHKITNNQTGQMVFSETVITSVGDEEG 141
>gi|40548389 dickkopf homolog 3 precursor [Homo sapiens]
Length = 350
Score = 57.8 bits (138), Expect = 8e-09
Identities = 24/60 (40%), Positives = 41/60 (68%)
Query: 73 SAPMDFRGLPGNYHKEENQEHQLGNNTLSSHLQIDKMTDNKTGEVLISENVVASIQPAEG 132
S+ ++ LP +YH E N + ++GNNT+ H +I K+T+N+TG+++ SE V+ S+ EG
Sbjct: 82 SSEVNLANLPPSYHNETNTDTKVGNNTIHVHREIHKITNNQTGQMVFSETVITSVGDEEG 141
>gi|28558969 mediator complex subunit 23 isoform b [Homo sapiens]
Length = 1365
Score = 30.0 bits (66), Expect = 1.9
Identities = 19/62 (30%), Positives = 27/62 (43%), Gaps = 4/62 (6%)
Query: 68 IDSLFSAPMDFRGLPGNYHKEENQEHQLGNNTLSSHLQIDKMTDNKTGEVLISENVVASI 127
I L P DFR ++ KE + EH L N+ + H+ K K E L E + +
Sbjct: 892 IQLLLLKPNDFRNRVSDFVKENSPEHWLQNDWHTKHMNYHK----KYPEKLYFEGLAEQV 947
Query: 128 QP 129
P
Sbjct: 948 DP 949
>gi|28558971 mediator complex subunit 23 isoform a [Homo sapiens]
Length = 1368
Score = 30.0 bits (66), Expect = 1.9
Identities = 19/62 (30%), Positives = 27/62 (43%), Gaps = 4/62 (6%)
Query: 68 IDSLFSAPMDFRGLPGNYHKEENQEHQLGNNTLSSHLQIDKMTDNKTGEVLISENVVASI 127
I L P DFR ++ KE + EH L N+ + H+ K K E L E + +
Sbjct: 886 IQLLLLKPNDFRNRVSDFVKENSPEHWLQNDWHTKHMNYHK----KYPEKLYFEGLAEQV 941
Query: 128 QP 129
P
Sbjct: 942 DP 943
>gi|45505173 B cell RAG associated protein [Homo sapiens]
Length = 561
Score = 30.0 bits (66), Expect = 1.9
Identities = 17/43 (39%), Positives = 20/43 (46%), Gaps = 12/43 (27%)
Query: 163 LHPRVAFWIIKLPRRRSHQDALEGGHWLSEKRHRLQAIRDGLR 205
LHP V F IK P HW + KR + +RDGLR
Sbjct: 275 LHPEVKFSAIKEP------------HWWTRKRFGIVRLRDGLR 305
>gi|71274148 pleckstrin homology domain containing, family G (with
RhoGef domain) member 1 [Homo sapiens]
Length = 1385
Score = 29.3 bits (64), Expect = 3.2
Identities = 29/126 (23%), Positives = 51/126 (40%), Gaps = 20/126 (15%)
Query: 94 QLGNNTLSSHLQIDKMTDNKTGEVLISENVVASIQPAEGSFEG----DLK--VPRMEEKE 147
++G + + LQ T+ + ++ +I + ++ DLK V + EE E
Sbjct: 621 EIGTSDRTRELQNSPKTEGQEEMTPFGSSIELTIDDIDHVYDNISYEDLKLMVAKREEAE 680
Query: 148 ALVPIQKATDSFHTELHPRVAFWIIKLPRRRSHQDA---------LEGGHWLSEKRHRLQ 198
+ P + A DS + P +AF R+ H L GG S+ H LQ
Sbjct: 681 S-TPSKSARDSVRPKSTPELAF----TKRQAGHSKGSLYAQTDGTLSGGEASSQSTHELQ 735
Query: 199 AIRDGL 204
A+ + +
Sbjct: 736 AVEENI 741
>gi|94536856 coiled-coil domain containing 106 [Homo sapiens]
Length = 280
Score = 29.3 bits (64), Expect = 3.2
Identities = 31/127 (24%), Positives = 46/127 (36%), Gaps = 33/127 (25%)
Query: 109 MTDNKTGEVLI--------SENVVASIQPAEGSFEGDLKVPRMEEKEALVPIQKATDSFH 160
M D++T E+ I + S+ P+ +FE E EA +S
Sbjct: 11 MKDDETFEISIPFDEAPHLDPQIFYSLSPSRRNFE--------EPPEAASSALALMNSVK 62
Query: 161 TELHPRVAFWIIKLPRRRSHQDALEGGHWLSEKRHRLQAIRDGLRKGTHKDVLEEGTESS 220
T+LH ALE WL ++ L+ RD LR K + E+
Sbjct: 63 TQLHM-----------------ALERNSWLQKRIEDLEEERDFLRCQLDKFISSARMEAE 105
Query: 221 SHSRLSP 227
H R+ P
Sbjct: 106 DHCRMKP 112
>gi|47578101 selenoprotein N, 1 isoform 2 precursor [Homo sapiens]
Length = 556
Score = 28.9 bits (63), Expect = 4.2
Identities = 27/79 (34%), Positives = 40/79 (50%), Gaps = 6/79 (7%)
Query: 4 ASPPAPARRHLLVLLLLLSTLVIPSAAAP---IHDADAQESSLGLTGLQSLLQGFSRLFL 60
A PPAP RR L LL + L +AAA A+AQ ++ L++L G LFL
Sbjct: 18 AQPPAPPRRRARSLALLGALLAAAAAAAVRVCARHAEAQAAARQELALKTL--GTDGLFL 75
Query: 61 KGNLLRGIDSLFSAPMDFR 79
+L D ++ +P +F+
Sbjct: 76 FSSLDTDGD-MYISPEEFK 93
>gi|47578099 selenoprotein N, 1 isoform 1 precursor [Homo sapiens]
Length = 590
Score = 28.9 bits (63), Expect = 4.2
Identities = 27/79 (34%), Positives = 40/79 (50%), Gaps = 6/79 (7%)
Query: 4 ASPPAPARRHLLVLLLLLSTLVIPSAAAP---IHDADAQESSLGLTGLQSLLQGFSRLFL 60
A PPAP RR L LL + L +AAA A+AQ ++ L++L G LFL
Sbjct: 18 AQPPAPPRRRARSLALLGALLAAAAAAAVRVCARHAEAQAAARQELALKTL--GTDGLFL 75
Query: 61 KGNLLRGIDSLFSAPMDFR 79
+L D ++ +P +F+
Sbjct: 76 FSSLDTDGD-MYISPEEFK 93
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 28.9 bits (63), Expect = 4.2
Identities = 17/80 (21%), Positives = 33/80 (41%)
Query: 84 NYHKEENQEHQLGNNTLSSHLQIDKMTDNKTGEVLISENVVASIQPAEGSFEGDLKVPRM 143
N H+ E + L Q++++ D + ++Q +G FE DL+
Sbjct: 1526 NVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDE 1585
Query: 144 EEKEALVPIQKATDSFHTEL 163
+ +E +Q+ + TEL
Sbjct: 1586 QNEEKRRQLQRQLHEYETEL 1605
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 28.9 bits (63), Expect = 4.2
Identities = 17/80 (21%), Positives = 33/80 (41%)
Query: 84 NYHKEENQEHQLGNNTLSSHLQIDKMTDNKTGEVLISENVVASIQPAEGSFEGDLKVPRM 143
N H+ E + L Q++++ D + ++Q +G FE DL+
Sbjct: 1533 NVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDE 1592
Query: 144 EEKEALVPIQKATDSFHTEL 163
+ +E +Q+ + TEL
Sbjct: 1593 QNEEKRRQLQRQLHEYETEL 1612
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 28.9 bits (63), Expect = 4.2
Identities = 17/80 (21%), Positives = 33/80 (41%)
Query: 84 NYHKEENQEHQLGNNTLSSHLQIDKMTDNKTGEVLISENVVASIQPAEGSFEGDLKVPRM 143
N H+ E + L Q++++ D + ++Q +G FE DL+
Sbjct: 1533 NVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDE 1592
Query: 144 EEKEALVPIQKATDSFHTEL 163
+ +E +Q+ + TEL
Sbjct: 1593 QNEEKRRQLQRQLHEYETEL 1612
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 28.9 bits (63), Expect = 4.2
Identities = 17/80 (21%), Positives = 33/80 (41%)
Query: 84 NYHKEENQEHQLGNNTLSSHLQIDKMTDNKTGEVLISENVVASIQPAEGSFEGDLKVPRM 143
N H+ E + L Q++++ D + ++Q +G FE DL+
Sbjct: 1526 NVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDE 1585
Query: 144 EEKEALVPIQKATDSFHTEL 163
+ +E +Q+ + TEL
Sbjct: 1586 QNEEKRRQLQRQLHEYETEL 1605
>gi|148762940 DVL-binding protein DAPLE [Homo sapiens]
Length = 2028
Score = 28.9 bits (63), Expect = 4.2
Identities = 28/103 (27%), Positives = 48/103 (46%), Gaps = 4/103 (3%)
Query: 86 HKEENQEHQLGNNTLSSHLQIDKMTDNKTGEVLISENVVASIQPAEGSFEGDLKVPRMEE 145
H+ E + QL + L++D+ TD K E L+ EN+V I + E +E+
Sbjct: 381 HELEKENLQLKSKL--HDLELDRDTDKKRIEELLEENMVLEIAQKQSMNESAHLGWELEQ 438
Query: 146 KEALVPIQKAT-DSFHTELHPRVAFWIIKLPR-RRSHQDALEG 186
+ A+ SF EL+ + I+KL + +S Q ++G
Sbjct: 439 LSKNADLSDASRKSFVFELNECASSRILKLEKENQSLQSTIQG 481
>gi|153281202 neuropeptide W preproprotein [Homo sapiens]
Length = 165
Score = 28.9 bits (63), Expect = 4.2
Identities = 21/50 (42%), Positives = 25/50 (50%), Gaps = 2/50 (4%)
Query: 8 APARRHLLVLLLLLSTLVIPSAAAPIHDADAQESSLGLTGLQSLLQGFSR 57
APA R L LLLLL L +PS A H A + ++G LL G R
Sbjct: 10 APASRPRLALLLLLLLLPLPSGAWYKHVASPRYHTVGRAA--GLLMGLRR 57
>gi|203097724 cadherin-like 29 [Homo sapiens]
Length = 788
Score = 28.5 bits (62), Expect = 5.5
Identities = 13/23 (56%), Positives = 16/23 (69%)
Query: 126 SIQPAEGSFEGDLKVPRMEEKEA 148
SIQ EGS EG L+ P+ME +A
Sbjct: 732 SIQGTEGSIEGFLEAPKMEMSQA 754
>gi|119709832 low density lipoprotein receptor-related protein 5
[Homo sapiens]
Length = 1615
Score = 28.1 bits (61), Expect = 7.2
Identities = 15/29 (51%), Positives = 19/29 (65%)
Query: 3 EASPPAPARRHLLVLLLLLSTLVIPSAAA 31
EA+PP P LL+LLLLL+ P+ AA
Sbjct: 2 EAAPPGPPWPLLLLLLLLLALCGCPAPAA 30
>gi|46255064 synaptotagmin-like 2 isoform d [Homo sapiens]
Length = 1256
Score = 28.1 bits (61), Expect = 7.2
Identities = 18/53 (33%), Positives = 27/53 (50%), Gaps = 3/53 (5%)
Query: 84 NYHKEENQEHQLGNNTLSSHLQIDKMTDNKTGEVLISENVVASIQPAEGSFEG 136
+Y ++E QE + N LS K T N + + L+SE +IQP+ G G
Sbjct: 141 DYSEQEIQESIIKTNVLSKDC---KDTFNDSLQKLLSETSTPAIQPSGGKVHG 190
>gi|46255062 synaptotagmin-like 2 isoform c [Homo sapiens]
Length = 1272
Score = 28.1 bits (61), Expect = 7.2
Identities = 18/53 (33%), Positives = 27/53 (50%), Gaps = 3/53 (5%)
Query: 84 NYHKEENQEHQLGNNTLSSHLQIDKMTDNKTGEVLISENVVASIQPAEGSFEG 136
+Y ++E QE + N LS K T N + + L+SE +IQP+ G G
Sbjct: 141 DYSEQEIQESIIKTNVLSKDC---KDTFNDSLQKLLSETSTPAIQPSGGKVHG 190
>gi|11321565 matrilin 3 precursor [Homo sapiens]
Length = 486
Score = 28.1 bits (61), Expect = 7.2
Identities = 15/24 (62%), Positives = 18/24 (75%)
Query: 7 PAPARRHLLVLLLLLSTLVIPSAA 30
PAPARR +LLLL L++PSAA
Sbjct: 4 PAPARRLPGLLLLLWPLLLLPSAA 27
>gi|223468602 t-complex 10-like 2 [Homo sapiens]
Length = 353
Score = 27.7 bits (60), Expect = 9.4
Identities = 26/96 (27%), Positives = 46/96 (47%), Gaps = 12/96 (12%)
Query: 139 KVPRMEEKEALVP-IQKATDSFHTELHPRVAFWIIKLPRRRSHQDALEGGHWLSEKRHRL 197
+VPR + +P +Q+ S H EL + + W + +SH DAL R +
Sbjct: 36 EVPREDSNAGEMPSLQQQITSLHQELGRQQSLWADIHRKLQSHMDAL---------RKQN 86
Query: 198 QAIRDGLRKGTHKDVLEEGTESSSHSRLSPRKTHLL 233
+ +R+ LR G + E G + ++ S + R++H L
Sbjct: 87 RELREELR-GLQRQQWEAGKKPAA-SPHAGRESHTL 120
>gi|110624774 mannose receptor, C type 2 [Homo sapiens]
Length = 1479
Score = 27.7 bits (60), Expect = 9.4
Identities = 24/57 (42%), Positives = 29/57 (50%), Gaps = 5/57 (8%)
Query: 1 MGEASP-PAPARRHLLVLLLLLSTLVIPSAAAPIHDADAQESSLGLT---GLQSLLQ 53
MG P PAP RHLL +LLL L + AP DA E ++ L GLQ L+
Sbjct: 1 MGPGRPAPAPWPRHLLRCVLLLGCLHLGRPGAP-GDAALPEPNVFLIFSHGLQGCLE 56
>gi|105553088 t-complex 10 [Homo sapiens]
Length = 326
Score = 27.7 bits (60), Expect = 9.4
Identities = 26/96 (27%), Positives = 46/96 (47%), Gaps = 12/96 (12%)
Query: 139 KVPRMEEKEALVP-IQKATDSFHTELHPRVAFWIIKLPRRRSHQDALEGGHWLSEKRHRL 197
+VPR + +P +Q+ S H EL + + W + +SH DAL R +
Sbjct: 9 EVPREDSNAGEMPSLQQQITSLHQELGRQQSLWADIHRKLQSHMDAL---------RKQN 59
Query: 198 QAIRDGLRKGTHKDVLEEGTESSSHSRLSPRKTHLL 233
+ +R+ LR G + E G + ++ S + R++H L
Sbjct: 60 RELREELR-GLQRQQWEAGKKPAA-SPHAGRESHTL 93
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.134 0.384
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,605,029
Number of Sequences: 37866
Number of extensions: 424477
Number of successful extensions: 1089
Number of sequences better than 10.0: 25
Number of HSP's better than 10.0 without gapping: 15
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 1073
Number of HSP's gapped (non-prelim): 26
length of query: 242
length of database: 18,247,518
effective HSP length: 99
effective length of query: 143
effective length of database: 14,498,784
effective search space: 2073326112
effective search space used: 2073326112
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.