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Search of human proteins with 7657514
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7657514 GTP-binding protein RHO6 [Homo sapiens]
(232 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7657514 GTP-binding protein RHO6 [Homo sapiens] 468 e-132
gi|4885069 ras homolog gene family, member E [Homo sapiens] 301 4e-82
gi|4885581 Rho family GTPase 2 [Homo sapiens] 250 6e-67
gi|10835049 ras homolog gene family, member A [Homo sapiens] 167 7e-42
gi|111494251 ras homolog gene family, member C precursor [Homo s... 165 3e-41
gi|111494248 ras homolog gene family, member C precursor [Homo s... 165 3e-41
gi|28395033 ras homolog gene family, member C precursor [Homo sa... 165 3e-41
gi|4757764 ras homolog gene family, member B [Homo sapiens] 165 3e-41
gi|7656900 ras homolog D [Homo sapiens] 156 1e-38
gi|38016957 ras homolog gene family, member F [Homo sapiens] 152 2e-37
gi|4506381 ras-related C3 botulinum toxin substrate 2 [Homo sapi... 149 3e-36
gi|9845511 ras-related C3 botulinum toxin substrate 1 isoform Ra... 147 6e-36
gi|4826962 ras-related C3 botulinum toxin substrate 3 (rho famil... 147 1e-35
gi|46249393 ras homolog gene family, member G [Homo sapiens] 141 5e-34
gi|9845509 ras-related C3 botulinum toxin substrate 1 isoform Ra... 136 2e-32
gi|50263042 ras-like protein TC10 [Homo sapiens] 136 2e-32
gi|16903164 ras homolog gene family, member J [Homo sapiens] 133 1e-31
gi|89903012 cell division cycle 42 isoform 1 [Homo sapiens] 132 3e-31
gi|4757952 cell division cycle 42 isoform 1 [Homo sapiens] 132 3e-31
gi|11034843 ras homolog gene family, member U [Homo sapiens] 131 4e-31
gi|16357472 cell division cycle 42 isoform 2 [Homo sapiens] 131 6e-31
gi|229577148 ras homolog gene family, member V [Homo sapiens] 119 3e-27
gi|4757770 ras homolog gene family, member H [Homo sapiens] 102 4e-22
gi|28629866 Rho-related BTB domain containing 1 [Homo sapiens] 93 2e-19
gi|237649113 Rho-related BTB domain containing 2 isoform 3 [Homo... 89 4e-18
gi|237649111 Rho-related BTB domain containing 2 isoform 2 [Homo... 89 4e-18
gi|237649109 Rho-related BTB domain containing 2 isoform 1 [Homo... 89 4e-18
gi|239915976 RAB19, member RAS oncogene family [Homo sapiens] 72 4e-13
gi|19923985 RAB3C, member RAS oncogene family [Homo sapiens] 69 3e-12
gi|106507164 RAB12, member RAS oncogene family [Homo sapiens] 69 3e-12
>gi|7657514 GTP-binding protein RHO6 [Homo sapiens]
Length = 232
Score = 468 bits (1205), Expect = e-132
Identities = 232/232 (100%), Positives = 232/232 (100%)
Query: 1 MKERRAPQPVVARCKLVLVGDVQCGKTAMLQVLAKDCYPETYVPTVFENYTACLETEEQR 60
MKERRAPQPVVARCKLVLVGDVQCGKTAMLQVLAKDCYPETYVPTVFENYTACLETEEQR
Sbjct: 1 MKERRAPQPVVARCKLVLVGDVQCGKTAMLQVLAKDCYPETYVPTVFENYTACLETEEQR 60
Query: 61 VELSLWDTSGSPYYDNVRPLCYSDSDAVLLCFDISRPETVDSALKKWRTEILDYCPSTRV 120
VELSLWDTSGSPYYDNVRPLCYSDSDAVLLCFDISRPETVDSALKKWRTEILDYCPSTRV
Sbjct: 61 VELSLWDTSGSPYYDNVRPLCYSDSDAVLLCFDISRPETVDSALKKWRTEILDYCPSTRV 120
Query: 121 LLIGCKTDLRTDLSTLMELSHQKQAPISYEQGCAIAKQLGAEIYLEGSAFTSEKSIHSIF 180
LLIGCKTDLRTDLSTLMELSHQKQAPISYEQGCAIAKQLGAEIYLEGSAFTSEKSIHSIF
Sbjct: 121 LLIGCKTDLRTDLSTLMELSHQKQAPISYEQGCAIAKQLGAEIYLEGSAFTSEKSIHSIF 180
Query: 181 RTASMLCLNKPSPLPQKSPVRSLSKRLLHLPSRSELISSTFKKEKAKSCSIM 232
RTASMLCLNKPSPLPQKSPVRSLSKRLLHLPSRSELISSTFKKEKAKSCSIM
Sbjct: 181 RTASMLCLNKPSPLPQKSPVRSLSKRLLHLPSRSELISSTFKKEKAKSCSIM 232
>gi|4885069 ras homolog gene family, member E [Homo sapiens]
Length = 244
Score = 301 bits (770), Expect = 4e-82
Identities = 142/244 (58%), Positives = 189/244 (77%), Gaps = 12/244 (4%)
Query: 1 MKERRAPQPVVAR----------CKLVLVGDVQCGKTAMLQVLAKDCYPETYVPTVFENY 50
MKERRA Q + ++ CK+V+VGD QCGKTA+L V AKDC+PE YVPTVFENY
Sbjct: 1 MKERRASQKLSSKSIMDPNQNVKCKIVVVGDSQCGKTALLHVFAKDCFPENYVPTVFENY 60
Query: 51 TACLETEEQRVELSLWDTSGSPYYDNVRPLCYSDSDAVLLCFDISRPETVDSALKKWRTE 110
TA E + QR+ELSLWDTSGSPYYDNVRPL Y DSDAVL+CFDISRPET+DS LKKW+ E
Sbjct: 61 TASFEIDTQRIELSLWDTSGSPYYDNVRPLSYPDSDAVLICFDISRPETLDSVLKKWKGE 120
Query: 111 ILDYCPSTRVLLIGCKTDLRTDLSTLMELSHQKQAPISYEQGCAIAKQLGAEIYLEGSAF 170
I ++CP+T++LL+GCK+DLRTD+STL+ELS+ +Q P+SY+QG +AKQ+GA Y+E SA
Sbjct: 121 IQEFCPNTKMLLVGCKSDLRTDVSTLVELSNHRQTPVSYDQGANMAKQIGAATYIECSAL 180
Query: 171 TSEKSIHSIFRTASMLCLNKPSPLPQKSPVRSLSKRLLHLPSRSEL--ISSTFKKEKAKS 228
SE S+ IF A++ C+NK + +++ + +KR+ H+PSR EL +++ +K+KAKS
Sbjct: 181 QSENSVRDIFHVATLACVNKTNKNVKRNKSQRATKRISHMPSRPELSAVATDLRKDKAKS 240
Query: 229 CSIM 232
C++M
Sbjct: 241 CTVM 244
>gi|4885581 Rho family GTPase 2 [Homo sapiens]
Length = 227
Score = 250 bits (639), Expect = 6e-67
Identities = 118/221 (53%), Positives = 164/221 (74%), Gaps = 1/221 (0%)
Query: 13 RCKLVLVGDVQCGKTAMLQVLAKDCYPETYVPTVFENYTACLETEEQRVELSLWDTSGSP 72
RCK+V+VGD +CGKTA+LQV AKD YP +YVPTVFENYTA E +++R+EL++WDTSGS
Sbjct: 7 RCKIVVVGDAECGKTALLQVFAKDAYPGSYVPTVFENYTASFEIDKRRIELNMWDTSGSS 66
Query: 73 YYDNVRPLCYSDSDAVLLCFDISRPETVDSALKKWRTEILDYCPSTRVLLIGCKTDLRTD 132
YYDNVRPL Y DSDAVL+CFDISRPET+DS LKKW+ E ++CP+ +V+L+GCK D+RTD
Sbjct: 67 YYDNVRPLAYPDSDAVLICFDISRPETLDSVLKKWQGETQEFCPNAKVVLVGCKLDMRTD 126
Query: 133 LSTLMELSHQKQAPISYEQGCAIAKQLGAEIYLEGSAFTSEKSIHSIFRTASMLCLNKPS 192
L+TL ELS Q+ P+++EQG +AKQ+GA Y+E S+ +SE+S+ +F A++ L +
Sbjct: 127 LATLRELSKQRLIPVTHEQGTVLAKQVGAVSYVECSSRSSERSVRDVFHVATVASLGRGH 186
Query: 193 PLPQKSPVRSLSKRLLHLPSRSEL-ISSTFKKEKAKSCSIM 232
+++ R +R L R + K++AKSC++M
Sbjct: 187 RQLRRTDSRRGMQRSAQLSGRPDRGNEGEIHKDRAKSCNLM 227
>gi|10835049 ras homolog gene family, member A [Homo sapiens]
Length = 193
Score = 167 bits (423), Expect = 7e-42
Identities = 80/176 (45%), Positives = 117/176 (66%), Gaps = 1/176 (0%)
Query: 13 RCKLVLVGDVQCGKTAMLQVLAKDCYPETYVPTVFENYTACLETEEQRVELSLWDTSGSP 72
R KLV+VGD CGKT +L V +KD +PE YVPTVFENY A +E + ++VEL+LWDT+G
Sbjct: 5 RKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQE 64
Query: 73 YYDNVRPLCYSDSDAVLLCFDISRPETVDSALKKWRTEILDYCPSTRVLLIGCKTDLRTD 132
YD +RPL Y D+D +L+CF I P+++++ +KW E+ +CP+ ++L+G K DLR D
Sbjct: 65 DYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRND 124
Query: 133 LSTLMELSHQKQAPISYEQGCAIAKQLGAEIYLEGSAFTSEKSIHSIFRTASMLCL 188
T EL+ KQ P+ E+G +A ++GA Y+E SA T + + +F A+ L
Sbjct: 125 EHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKD-GVREVFEMATRAAL 179
>gi|111494251 ras homolog gene family, member C precursor [Homo
sapiens]
Length = 193
Score = 165 bits (418), Expect = 3e-41
Identities = 80/172 (46%), Positives = 115/172 (66%), Gaps = 1/172 (0%)
Query: 13 RCKLVLVGDVQCGKTAMLQVLAKDCYPETYVPTVFENYTACLETEEQRVELSLWDTSGSP 72
R KLV+VGD CGKT +L V +KD +PE YVPTVFENY A +E + ++VEL+LWDT+G
Sbjct: 5 RKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDGKQVELALWDTAGQE 64
Query: 73 YYDNVRPLCYSDSDAVLLCFDISRPETVDSALKKWRTEILDYCPSTRVLLIGCKTDLRTD 132
YD +RPL Y D+D +L+CF I P+++++ +KW E+ +CP+ ++L+G K DLR D
Sbjct: 65 DYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRQD 124
Query: 133 LSTLMELSHQKQAPISYEQGCAIAKQLGAEIYLEGSAFTSEKSIHSIFRTAS 184
T EL+ KQ P+ E+G +A ++ A YLE SA T E + +F A+
Sbjct: 125 EHTRRELAKMKQEPVRSEEGRDMANRISAFGYLECSAKTKE-GVREVFEMAT 175
>gi|111494248 ras homolog gene family, member C precursor [Homo
sapiens]
Length = 193
Score = 165 bits (418), Expect = 3e-41
Identities = 80/172 (46%), Positives = 115/172 (66%), Gaps = 1/172 (0%)
Query: 13 RCKLVLVGDVQCGKTAMLQVLAKDCYPETYVPTVFENYTACLETEEQRVELSLWDTSGSP 72
R KLV+VGD CGKT +L V +KD +PE YVPTVFENY A +E + ++VEL+LWDT+G
Sbjct: 5 RKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDGKQVELALWDTAGQE 64
Query: 73 YYDNVRPLCYSDSDAVLLCFDISRPETVDSALKKWRTEILDYCPSTRVLLIGCKTDLRTD 132
YD +RPL Y D+D +L+CF I P+++++ +KW E+ +CP+ ++L+G K DLR D
Sbjct: 65 DYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRQD 124
Query: 133 LSTLMELSHQKQAPISYEQGCAIAKQLGAEIYLEGSAFTSEKSIHSIFRTAS 184
T EL+ KQ P+ E+G +A ++ A YLE SA T E + +F A+
Sbjct: 125 EHTRRELAKMKQEPVRSEEGRDMANRISAFGYLECSAKTKE-GVREVFEMAT 175
>gi|28395033 ras homolog gene family, member C precursor [Homo
sapiens]
Length = 193
Score = 165 bits (418), Expect = 3e-41
Identities = 80/172 (46%), Positives = 115/172 (66%), Gaps = 1/172 (0%)
Query: 13 RCKLVLVGDVQCGKTAMLQVLAKDCYPETYVPTVFENYTACLETEEQRVELSLWDTSGSP 72
R KLV+VGD CGKT +L V +KD +PE YVPTVFENY A +E + ++VEL+LWDT+G
Sbjct: 5 RKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDGKQVELALWDTAGQE 64
Query: 73 YYDNVRPLCYSDSDAVLLCFDISRPETVDSALKKWRTEILDYCPSTRVLLIGCKTDLRTD 132
YD +RPL Y D+D +L+CF I P+++++ +KW E+ +CP+ ++L+G K DLR D
Sbjct: 65 DYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRQD 124
Query: 133 LSTLMELSHQKQAPISYEQGCAIAKQLGAEIYLEGSAFTSEKSIHSIFRTAS 184
T EL+ KQ P+ E+G +A ++ A YLE SA T E + +F A+
Sbjct: 125 EHTRRELAKMKQEPVRSEEGRDMANRISAFGYLECSAKTKE-GVREVFEMAT 175
>gi|4757764 ras homolog gene family, member B [Homo sapiens]
Length = 196
Score = 165 bits (418), Expect = 3e-41
Identities = 80/178 (44%), Positives = 117/178 (65%), Gaps = 1/178 (0%)
Query: 13 RCKLVLVGDVQCGKTAMLQVLAKDCYPETYVPTVFENYTACLETEEQRVELSLWDTSGSP 72
R KLV+VGD CGKT +L V +KD +PE YVPTVFENY A +E + ++VEL+LWDT+G
Sbjct: 5 RKKLVVVGDGACGKTCLLIVFSKDEFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQE 64
Query: 73 YYDNVRPLCYSDSDAVLLCFDISRPETVDSALKKWRTEILDYCPSTRVLLIGCKTDLRTD 132
YD +RPL Y D+D +L+CF + P+++++ +KW E+ +CP+ ++L+ K DLR+D
Sbjct: 65 DYDRLRPLSYPDTDVILMCFSVDSPDSLENIPEKWVPEVKHFCPNVPIILVANKKDLRSD 124
Query: 133 LSTLMELSHQKQAPISYEQGCAIAKQLGAEIYLEGSAFTSEKSIHSIFRTASMLCLNK 190
EL+ KQ P+ + G A+A ++ A YLE SA T E + +F TA+ L K
Sbjct: 125 EHVRTELARMKQEPVRTDDGRAMAVRIQAYDYLECSAKTKE-GVREVFETATRAALQK 181
>gi|7656900 ras homolog D [Homo sapiens]
Length = 210
Score = 156 bits (395), Expect = 1e-38
Identities = 73/181 (40%), Positives = 114/181 (62%), Gaps = 1/181 (0%)
Query: 9 PVVARCKLVLVGDVQCGKTAMLQVLAKDCYPETYVPTVFENYTACLETEEQRVELSLWDT 68
P V K+VLVGD CGKT++L V A +PE+Y PTVFE Y L+ + + V L +WDT
Sbjct: 13 PGVRSVKVVLVGDGGCGKTSLLMVFADGAFPESYTPTVFERYMVNLQVKGKPVHLHIWDT 72
Query: 69 SGSPYYDNVRPLCYSDSDAVLLCFDISRPETVDSALKKWRTEILDYCPSTRVLLIGCKTD 128
+G YD +RPL Y D+ +LLCFD++ P + D+ +W E+ +C ++++GCKTD
Sbjct: 73 AGQDDYDRLRPLFYPDASVLLLCFDVTSPNSFDNIFNRWYPEVNHFCKKVPIIVVGCKTD 132
Query: 129 LRTDLSTLMELSHQKQAPISYEQGCAIAKQLGAEIYLEGSAFTSEKSIHSIFRTASMLCL 188
LR D S + +L P++Y +G +A+ +GA YLE SA + ++H++F+ A+ + L
Sbjct: 133 LRKDKSLVNKLRRNGLEPVTYHRGQEMARSVGAVAYLECSARLHD-NVHAVFQEAAEVAL 191
Query: 189 N 189
+
Sbjct: 192 S 192
>gi|38016957 ras homolog gene family, member F [Homo sapiens]
Length = 211
Score = 152 bits (385), Expect = 2e-37
Identities = 76/189 (40%), Positives = 116/189 (61%), Gaps = 1/189 (0%)
Query: 1 MKERRAPQPVVARCKLVLVGDVQCGKTAMLQVLAKDCYPETYVPTVFENYTACLETEEQR 60
+ + AP P K+V+VGD CGKT++L V ++ +PE Y P+VFE YTA + +
Sbjct: 7 LAQTAAPGPGRKELKIVIVGDGGCGKTSLLMVYSQGSFPEHYAPSVFEKYTASVTVGSKE 66
Query: 61 VELSLWDTSGSPYYDNVRPLCYSDSDAVLLCFDISRPETVDSALKKWRTEILDYCPSTRV 120
V L+L+DT+G YD +RPL Y ++ VL+C+D+ P + D+ L KW E+ +C +
Sbjct: 67 VTLNLYDTAGQEDYDRLRPLSYQNTHLVLICYDVMNPTSYDNVLIKWFPEVTHFCRGIPM 126
Query: 121 LLIGCKTDLRTDLSTLMELSHQKQAPISYEQGCAIAKQLGAEIYLEGSAFTSEKSIHSIF 180
+LIGCKTDLR D L +L + PI+Y QG + +Q+ A +YLE SA E ++ +F
Sbjct: 127 VLIGCKTDLRKDKEQLRKLRAAQLEPITYMQGLSACEQIRAALYLECSAKFRE-NVEDVF 185
Query: 181 RTASMLCLN 189
R A+ + L+
Sbjct: 186 REAAKVALS 194
>gi|4506381 ras-related C3 botulinum toxin substrate 2 [Homo
sapiens]
Length = 192
Score = 149 bits (375), Expect = 3e-36
Identities = 77/191 (40%), Positives = 116/191 (60%), Gaps = 6/191 (3%)
Query: 15 KLVLVGDVQCGKTAMLQVLAKDCYPETYVPTVFENYTACLETEEQRVELSLWDTSGSPYY 74
K V+VGD GKT +L + +P Y+PTVF+NY+A + + + V L LWDT+G Y
Sbjct: 5 KCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPVNLGLWDTAGQEDY 64
Query: 75 DNVRPLCYSDSDAVLLCFDISRPETVDSALKKWRTEILDYCPSTRVLLIGCKTDLRTDLS 134
D +RPL Y +D L+CF + P + ++ KW E+ +CPST ++L+G K DLR D
Sbjct: 65 DRLRPLSYPQTDVFLICFSLVSPASYENVRAKWFPEVRHHCPSTPIILVGTKLDLRDDKD 124
Query: 135 TLMELSHQKQAPISYEQGCAIAKQLGAEIYLEGSAFTSEKSIHSIFRTA--SMLCLNKPS 192
T+ +L +K API+Y QG A+AK++ + YLE SA T ++ + ++F A ++LC P
Sbjct: 125 TIEKLKEKKLAPITYPQGLALAKEIDSVKYLECSALT-QRGLKTVFDEAIRAVLC---PQ 180
Query: 193 PLPQKSPVRSL 203
P Q+ SL
Sbjct: 181 PTRQQKRACSL 191
>gi|9845511 ras-related C3 botulinum toxin substrate 1 isoform Rac1
[Homo sapiens]
Length = 192
Score = 147 bits (372), Expect = 6e-36
Identities = 74/185 (40%), Positives = 115/185 (62%), Gaps = 6/185 (3%)
Query: 15 KLVLVGDVQCGKTAMLQVLAKDCYPETYVPTVFENYTACLETEEQRVELSLWDTSGSPYY 74
K V+VGD GKT +L + +P Y+PTVF+NY+A + + + V L LWDT+G Y
Sbjct: 5 KCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDY 64
Query: 75 DNVRPLCYSDSDAVLLCFDISRPETVDSALKKWRTEILDYCPSTRVLLIGCKTDLRTDLS 134
D +RPL Y +D L+CF + P + ++ KW E+ +CP+T ++L+G K DLR D
Sbjct: 65 DRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKD 124
Query: 135 TLMELSHQKQAPISYEQGCAIAKQLGAEIYLEGSAFTSEKSIHSIFRTA--SMLCLNKPS 192
T+ +L +K PI+Y QG A+AK++GA YLE SA T ++ + ++F A ++LC P
Sbjct: 125 TIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALT-QRGLKTVFDEAIRAVLC---PP 180
Query: 193 PLPQK 197
P+ ++
Sbjct: 181 PVKKR 185
>gi|4826962 ras-related C3 botulinum toxin substrate 3 (rho family,
small GTP binding protein Rac3) [Homo sapiens]
Length = 192
Score = 147 bits (370), Expect = 1e-35
Identities = 76/187 (40%), Positives = 113/187 (60%), Gaps = 8/187 (4%)
Query: 15 KLVLVGDVQCGKTAMLQVLAKDCYPETYVPTVFENYTACLETEEQRVELSLWDTSGSPYY 74
K V+VGD GKT +L + +P Y+PTVF+NY+A + + + V L LWDT+G Y
Sbjct: 5 KCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDY 64
Query: 75 DNVRPLCYSDSDAVLLCFDISRPETVDSALKKWRTEILDYCPSTRVLLIGCKTDLRTDLS 134
D +RPL Y +D L+CF + P + ++ KW E+ +CP T +LL+G K DLR D
Sbjct: 65 DRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPHTPILLVGTKLDLRDDKD 124
Query: 135 TLMELSHQKQAPISYEQGCAIAKQLGAEIYLEGSAFTSEKSIHSIFRTA--SMLCLNKPS 192
T+ L +K API+Y QG A+A+++G+ YLE SA T ++ + ++F A ++LC
Sbjct: 125 TIERLRDKKLAPITYPQGLAMAREIGSVKYLECSALT-QRGLKTVFDEAIRAVLC----- 178
Query: 193 PLPQKSP 199
P P K P
Sbjct: 179 PPPVKKP 185
>gi|46249393 ras homolog gene family, member G [Homo sapiens]
Length = 191
Score = 141 bits (355), Expect = 5e-34
Identities = 72/180 (40%), Positives = 106/180 (58%), Gaps = 2/180 (1%)
Query: 15 KLVLVGDVQCGKTAMLQVLAKDCYPETYVPTVFENYTACLETEEQRVELSLWDTSGSPYY 74
K V+VGD GKT +L + +P+ Y+PTVF+NY+A + + V L+LWDT+G Y
Sbjct: 5 KCVVVGDGAVGKTCLLICYTTNAFPKEYIPTVFDNYSAQSAVDGRTVNLNLWDTAGQEEY 64
Query: 75 DNVRPLCYSDSDAVLLCFDISRPETVDSALKKWRTEILDYCPSTRVLLIGCKTDLRTDLS 134
D +R L Y ++ ++CF I+ P + ++ KW E+ +CP +LL+G K DLR
Sbjct: 65 DRLRTLSYPQTNVFVICFSIASPPSYENVRHKWHPEVCHHCPDVPILLVGTKKDLRAQPD 124
Query: 135 TLMELSHQKQAPISYEQGCAIAKQLGAEIYLEGSAFTSEKSIHSIFRTASMLCLNKPSPL 194
TL L Q QAPI+ +QG A+AKQ+ A YLE SA + + +F A LN P+P+
Sbjct: 125 TLRRLKEQGQAPITPQQGQALAKQIHAVRYLECSAL-QQDGVKEVFAEAVRAVLN-PTPI 182
>gi|9845509 ras-related C3 botulinum toxin substrate 1 isoform Rac1b
[Homo sapiens]
Length = 211
Score = 136 bits (342), Expect = 2e-32
Identities = 74/204 (36%), Positives = 115/204 (56%), Gaps = 25/204 (12%)
Query: 15 KLVLVGDVQCGKTAMLQVLAKDCYPETYVPTVFENYTACLETEEQRVELSLWDTSGSPYY 74
K V+VGD GKT +L + +P Y+PTVF+NY+A + + + V L LWDT+G Y
Sbjct: 5 KCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDY 64
Query: 75 DNVRPLCYSDS-------------------DAVLLCFDISRPETVDSALKKWRTEILDYC 115
D +RPL Y + D L+CF + P + ++ KW E+ +C
Sbjct: 65 DRLRPLSYPQTVGETYGKDITSRGKDKPIADVFLICFSLVSPASFENVRAKWYPEVRHHC 124
Query: 116 PSTRVLLIGCKTDLRTDLSTLMELSHQKQAPISYEQGCAIAKQLGAEIYLEGSAFTSEKS 175
P+T ++L+G K DLR D T+ +L +K PI+Y QG A+AK++GA YLE SA T ++
Sbjct: 125 PNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALT-QRG 183
Query: 176 IHSIFRTA--SMLCLNKPSPLPQK 197
+ ++F A ++LC P P+ ++
Sbjct: 184 LKTVFDEAIRAVLC---PPPVKKR 204
>gi|50263042 ras-like protein TC10 [Homo sapiens]
Length = 205
Score = 136 bits (342), Expect = 2e-32
Identities = 74/193 (38%), Positives = 109/193 (56%), Gaps = 6/193 (3%)
Query: 9 PVVARCKLVLVGDVQCGKTAMLQVLAKDCYPETYVPTVFENYTACLETEEQRVELSLWDT 68
P K V+VGD GKT +L A D +PE YVPTVF++Y + ++ L L+DT
Sbjct: 5 PGALMLKCVVVGDGAVGKTCLLMSYANDAFPEEYVPTVFDHYAVSVTVGGKQYLLGLYDT 64
Query: 69 SGSPYYDNVRPLCYSDSDAVLLCFDISRPETVDSALKKWRTEILDYCPSTRVLLIGCKTD 128
+G YD +RPL Y +D L+CF + P + + ++W E+ +Y P+ LLIG + D
Sbjct: 65 AGQEDYDRLRPLSYPMTDVFLICFSVVNPASFQNVKEEWVPELKEYAPNVPFLLIGTQID 124
Query: 129 LRTDLSTLMELSHQKQAPISYEQGCAIAKQLGAEIYLEGSAFTSEKSIHSIFRTASMLCL 188
LR D TL L+ K+ PI EQG +AK++GA Y+E SA T +K + ++F A + L
Sbjct: 125 LRDDPKTLARLNDMKEKPICVEQGQKLAKEIGACCYVECSALT-QKGLKTVFDEAIIAIL 183
Query: 189 NKPSPLPQKSPVR 201
P+K V+
Sbjct: 184 T-----PKKHTVK 191
>gi|16903164 ras homolog gene family, member J [Homo sapiens]
Length = 214
Score = 133 bits (335), Expect = 1e-31
Identities = 67/169 (39%), Positives = 101/169 (59%), Gaps = 1/169 (0%)
Query: 15 KLVLVGDVQCGKTAMLQVLAKDCYPETYVPTVFENYTACLETEEQRVELSLWDTSGSPYY 74
K V+VGD GKT +L A D +PE YVPTVF++Y + ++ L L+DT+G Y
Sbjct: 23 KCVVVGDGAVGKTCLLMSYANDAFPEEYVPTVFDHYAVTVTVGGKQHLLGLYDTAGQEDY 82
Query: 75 DNVRPLCYSDSDAVLLCFDISRPETVDSALKKWRTEILDYCPSTRVLLIGCKTDLRTDLS 134
+ +RPL Y ++D L+CF + P + + ++W E+ D P +LIG + DLR D
Sbjct: 83 NQLRPLSYPNTDVFLICFSVVNPASYHNVQEEWVPELKDCMPHVPYVLIGTQIDLRDDPK 142
Query: 135 TLMELSHQKQAPISYEQGCAIAKQLGAEIYLEGSAFTSEKSIHSIFRTA 183
TL L + K+ P++YE G +AK +GA+ YLE SA T +K + ++F A
Sbjct: 143 TLARLLYMKEKPLTYEHGVKLAKAIGAQCYLECSALT-QKGLKAVFDEA 190
>gi|89903012 cell division cycle 42 isoform 1 [Homo sapiens]
Length = 191
Score = 132 bits (332), Expect = 3e-31
Identities = 70/179 (39%), Positives = 102/179 (56%), Gaps = 1/179 (0%)
Query: 15 KLVLVGDVQCGKTAMLQVLAKDCYPETYVPTVFENYTACLETEEQRVELSLWDTSGSPYY 74
K V+VGD GKT +L + +P YVPTVF+NY + + L L+DT+G Y
Sbjct: 5 KCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAGQEDY 64
Query: 75 DNVRPLCYSDSDAVLLCFDISRPETVDSALKKWRTEILDYCPSTRVLLIGCKTDLRTDLS 134
D +RPL Y +D L+CF + P + ++ +KW EI +CP T LL+G + DLR D S
Sbjct: 65 DRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQIDLRDDPS 124
Query: 135 TLMELSHQKQAPISYEQGCAIAKQLGAEIYLEGSAFTSEKSIHSIFRTASMLCLNKPSP 193
T+ +L+ KQ PI+ E +A+ L A Y+E SA T +K + ++F A + L P P
Sbjct: 125 TIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALT-QKGLKNVFDEAILAALEPPEP 182
>gi|4757952 cell division cycle 42 isoform 1 [Homo sapiens]
Length = 191
Score = 132 bits (332), Expect = 3e-31
Identities = 70/179 (39%), Positives = 102/179 (56%), Gaps = 1/179 (0%)
Query: 15 KLVLVGDVQCGKTAMLQVLAKDCYPETYVPTVFENYTACLETEEQRVELSLWDTSGSPYY 74
K V+VGD GKT +L + +P YVPTVF+NY + + L L+DT+G Y
Sbjct: 5 KCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAGQEDY 64
Query: 75 DNVRPLCYSDSDAVLLCFDISRPETVDSALKKWRTEILDYCPSTRVLLIGCKTDLRTDLS 134
D +RPL Y +D L+CF + P + ++ +KW EI +CP T LL+G + DLR D S
Sbjct: 65 DRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQIDLRDDPS 124
Query: 135 TLMELSHQKQAPISYEQGCAIAKQLGAEIYLEGSAFTSEKSIHSIFRTASMLCLNKPSP 193
T+ +L+ KQ PI+ E +A+ L A Y+E SA T +K + ++F A + L P P
Sbjct: 125 TIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALT-QKGLKNVFDEAILAALEPPEP 182
>gi|11034843 ras homolog gene family, member U [Homo sapiens]
Length = 258
Score = 131 bits (330), Expect = 4e-31
Identities = 68/193 (35%), Positives = 112/193 (58%), Gaps = 3/193 (1%)
Query: 15 KLVLVGDVQCGKTAMLQVLAKDCYPETYVPTVFENYTACLETEEQRVELSLWDTSGSPYY 74
K VLVGD GKT+++ + YP Y+PT F+N++A + + + V L L DT+G +
Sbjct: 51 KCVLVGDGAVGKTSLVVSYTTNGYPTEYIPTAFDNFSAVVSVDGRPVRLQLCDTAGQDEF 110
Query: 75 DNVRPLCYSDSDAVLLCFDISRPETVDSALKKWRTEILDYCPSTRVLLIGCKTDLRTDLS 134
D +RPLCY+++D LLCF + P + + +KW EI +CP ++L+G ++DLR D+
Sbjct: 111 DKLRPLCYTNTDIFLLCFSVVSPSSFQNVSEKWVPEIRCHCPKAPIILVGTQSDLREDVK 170
Query: 135 TLMELSHQKQAPISYEQGCAIAKQLGAEIYLEGSAFTSEKSIHSIFRTASM--LCLNKPS 192
L+EL K+ P+ E A+++ A Y+E SA T +K++ +F A + + +
Sbjct: 171 VLIELDKCKEKPVPEEAAKLCAEEIKAASYIECSALT-QKNLKEVFDAAIVAGIQYSDTQ 229
Query: 193 PLPQKSPVRSLSK 205
P+KS R+ K
Sbjct: 230 QQPKKSKSRTPDK 242
>gi|16357472 cell division cycle 42 isoform 2 [Homo sapiens]
Length = 191
Score = 131 bits (329), Expect = 6e-31
Identities = 69/183 (37%), Positives = 104/183 (56%), Gaps = 1/183 (0%)
Query: 15 KLVLVGDVQCGKTAMLQVLAKDCYPETYVPTVFENYTACLETEEQRVELSLWDTSGSPYY 74
K V+VGD GKT +L + +P YVPTVF+NY + + L L+DT+G Y
Sbjct: 5 KCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAGQEDY 64
Query: 75 DNVRPLCYSDSDAVLLCFDISRPETVDSALKKWRTEILDYCPSTRVLLIGCKTDLRTDLS 134
D +RPL Y +D L+CF + P + ++ +KW EI +CP T LL+G + DLR D S
Sbjct: 65 DRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQIDLRDDPS 124
Query: 135 TLMELSHQKQAPISYEQGCAIAKQLGAEIYLEGSAFTSEKSIHSIFRTASMLCLNKPSPL 194
T+ +L+ KQ PI+ E +A+ L A Y+E SA T ++ + ++F A + L P
Sbjct: 125 TIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALT-QRGLKNVFDEAILAALEPPETQ 183
Query: 195 PQK 197
P++
Sbjct: 184 PKR 186
>gi|229577148 ras homolog gene family, member V [Homo sapiens]
Length = 236
Score = 119 bits (297), Expect = 3e-27
Identities = 67/206 (32%), Positives = 112/206 (54%), Gaps = 5/206 (2%)
Query: 4 RRAPQPVVARCKLVLVGDVQCGKTAMLQVLAKDCYPETYVPTVFENYTACLETEEQRVEL 63
RR P K VLVGD GK++++ + YP Y PT + ++ + + V +
Sbjct: 22 RRRSAPPELGIKCVLVGDGAVGKSSLIVSYTCNGYPARYRPTALDTFSVQVLVDGAPVRI 81
Query: 64 SLWDTSGSPYYDNVRPLCYSDSDAVLLCFDISRPETVDSALKKWRTEILDYCPSTRVLLI 123
LWDT+G +D +R LCY D+D L CF + +P + + +KW EI + P VLL+
Sbjct: 82 ELWDTAGQEDFDRLRSLCYPDTDVFLACFSVVQPSSFQNITEKWLPEIRTHNPQAPVLLV 141
Query: 124 GCKTDLRTDLSTLMELSH-QKQAPISYEQGCAIAKQLGAEIYLEGSAFTSEKSIHSIFRT 182
G + DLR D++ L++L ++ P+ Q +A+++ A YLE SA T +K++ +F +
Sbjct: 142 GTQADLRDDVNVLIQLDQGGREGPVPQPQAQGLAEKIRACCYLECSALT-QKNLKEVFDS 200
Query: 183 ASMLCLNKPSPLPQK---SPVRSLSK 205
A + + + L +K VR+LS+
Sbjct: 201 AILSAIEHKARLEKKLNAKGVRTLSR 226
>gi|4757770 ras homolog gene family, member H [Homo sapiens]
Length = 191
Score = 102 bits (253), Expect = 4e-22
Identities = 56/181 (30%), Positives = 98/181 (54%), Gaps = 8/181 (4%)
Query: 10 VVARCKLVLVGDVQCGKTAMLQVLAKDCYPETYVPTVFENYTACLETEEQRVELSLWDTS 69
+++ K VLVGD GKT++L + +PE Y PTV+EN + + ++ L LWDT+
Sbjct: 1 MLSSIKCVLVGDSAVGKTSLLVRFTSETFPEAYKPTVYENTGVDVFMDGIQISLGLWDTA 60
Query: 70 GSPYYDNVRPLCYSDSDAVLLCFDISRPETVDSALKKWRTEILDYCPSTRVLLIGCKTDL 129
G+ + ++RPL Y +D VL+C+ ++ + + KW EI P T VL++ +TD
Sbjct: 61 GNDAFRSIRPLSYQQADVVLMCYSVANHNSFLNLKNKWIGEIRSNLPCTPVLVVATQTDQ 120
Query: 130 RTDLSTLMELSHQKQAPISYEQGCAIAKQLGAEIYLEGSAFTSEKSIHSIFRTASMLCLN 189
R E+ + + ++ +G +A+ + A+ YLE SA S + + +F A +N
Sbjct: 121 R-------EMGPHRASCVNAMEGKKLAQDVRAKGYLECSAL-SNRGVQQVFECAVRTAVN 172
Query: 190 K 190
+
Sbjct: 173 Q 173
>gi|28629866 Rho-related BTB domain containing 1 [Homo sapiens]
Length = 696
Score = 93.2 bits (230), Expect = 2e-19
Identities = 77/230 (33%), Positives = 105/230 (45%), Gaps = 32/230 (13%)
Query: 8 QPVVARCKLVLVGDVQCGKTAMLQVLAKDCYPE--------TYVPTVF--ENYTACLET- 56
+P V K V+VGD GKT + + A+ C T+VPTV+ + Y C E
Sbjct: 9 RPNVETIKCVVVGDNAVGKTRL--ICARACNTTLTQYQLLATHVPTVWAIDQYRVCQEVL 66
Query: 57 -------EEQRVELSLWDTSGSPYYDNVRPLCYSDSDAVLLCFDISRPETVDSALKKWRT 109
+E V L LWDT G + D R Y SD V+LCF I+ P +++ W
Sbjct: 67 ERSRDVVDEVSVSLRLWDTFGDHHKD--RRFAYGRSDVVVLCFSIANPNSLNHVKSMWYP 124
Query: 110 EILDYCPSTRVLLIGCKTDLR-TDLSTLMELSHQKQAPISY------EQGCAIAKQLGAE 162
EI +CP T V+L+GC+ DLR DL + PI E+G +AK+LG
Sbjct: 125 EIKHFCPRTPVILVGCQLDLRYADLEAVNRARRPLARPIKRGDILPPEKGREVAKELGLP 184
Query: 163 IYLEGSAFTSEKSIHSIFRTASMLCLNKPSPLP-QKSPVRSLSKRLLHLP 211
Y E S F + I +F A L L KS ++ + K LL P
Sbjct: 185 -YYETSVF-DQFGIKDVFDNAIRAALISRRHLQFWKSHLKKVQKPLLQAP 232
>gi|237649113 Rho-related BTB domain containing 2 isoform 3 [Homo
sapiens]
Length = 727
Score = 88.6 bits (218), Expect = 4e-18
Identities = 73/230 (31%), Positives = 104/230 (45%), Gaps = 32/230 (13%)
Query: 8 QPVVARCKLVLVGDVQCGKTAMLQVLAKDCYPE--------TYVPTVF--ENYTACLETE 57
+P V K V+VGD GKT + + A+ C T+VPTV+ + Y C E
Sbjct: 9 RPNVETIKCVVVGDNAVGKTRL--ICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVL 66
Query: 58 EQR--------VELSLWDTSGSPYYDNVRPLCYSDSDAVLLCFDISRPETVDSALKKWRT 109
E+ V L LWDT G + D R Y SD V+LCF I+ P ++ W
Sbjct: 67 ERSRDVVDDVSVSLRLWDTFGDHHKD--RRFAYGRSDVVVLCFSIANPNSLHHVKTMWYP 124
Query: 110 EILDYCPSTRVLLIGCKTDLR-TDLSTLMELSHQKQAPIS------YEQGCAIAKQLGAE 162
EI +CP V+L+GC+ DLR DL + PI E+G +AK+LG
Sbjct: 125 EIKHFCPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKELGIP 184
Query: 163 IYLEGSAFTSEKSIHSIFRTASMLCLNKPSPLP-QKSPVRSLSKRLLHLP 211
Y ++ ++ I +F A L L KS +R++ + LL P
Sbjct: 185 YY--ETSVVAQFGIKDVFDNAIRAALISRRHLQFWKSHLRNVQRPLLQAP 232
>gi|237649111 Rho-related BTB domain containing 2 isoform 2 [Homo
sapiens]
Length = 734
Score = 88.6 bits (218), Expect = 4e-18
Identities = 73/230 (31%), Positives = 104/230 (45%), Gaps = 32/230 (13%)
Query: 8 QPVVARCKLVLVGDVQCGKTAMLQVLAKDCYPE--------TYVPTVF--ENYTACLETE 57
+P V K V+VGD GKT + + A+ C T+VPTV+ + Y C E
Sbjct: 16 RPNVETIKCVVVGDNAVGKTRL--ICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVL 73
Query: 58 EQR--------VELSLWDTSGSPYYDNVRPLCYSDSDAVLLCFDISRPETVDSALKKWRT 109
E+ V L LWDT G + D R Y SD V+LCF I+ P ++ W
Sbjct: 74 ERSRDVVDDVSVSLRLWDTFGDHHKD--RRFAYGRSDVVVLCFSIANPNSLHHVKTMWYP 131
Query: 110 EILDYCPSTRVLLIGCKTDLR-TDLSTLMELSHQKQAPIS------YEQGCAIAKQLGAE 162
EI +CP V+L+GC+ DLR DL + PI E+G +AK+LG
Sbjct: 132 EIKHFCPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKELGIP 191
Query: 163 IYLEGSAFTSEKSIHSIFRTASMLCLNKPSPLP-QKSPVRSLSKRLLHLP 211
Y ++ ++ I +F A L L KS +R++ + LL P
Sbjct: 192 YY--ETSVVAQFGIKDVFDNAIRAALISRRHLQFWKSHLRNVQRPLLQAP 239
>gi|237649109 Rho-related BTB domain containing 2 isoform 1 [Homo
sapiens]
Length = 749
Score = 88.6 bits (218), Expect = 4e-18
Identities = 73/230 (31%), Positives = 104/230 (45%), Gaps = 32/230 (13%)
Query: 8 QPVVARCKLVLVGDVQCGKTAMLQVLAKDCYPE--------TYVPTVF--ENYTACLETE 57
+P V K V+VGD GKT + + A+ C T+VPTV+ + Y C E
Sbjct: 31 RPNVETIKCVVVGDNAVGKTRL--ICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVL 88
Query: 58 EQR--------VELSLWDTSGSPYYDNVRPLCYSDSDAVLLCFDISRPETVDSALKKWRT 109
E+ V L LWDT G + D R Y SD V+LCF I+ P ++ W
Sbjct: 89 ERSRDVVDDVSVSLRLWDTFGDHHKD--RRFAYGRSDVVVLCFSIANPNSLHHVKTMWYP 146
Query: 110 EILDYCPSTRVLLIGCKTDLR-TDLSTLMELSHQKQAPIS------YEQGCAIAKQLGAE 162
EI +CP V+L+GC+ DLR DL + PI E+G +AK+LG
Sbjct: 147 EIKHFCPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKELGIP 206
Query: 163 IYLEGSAFTSEKSIHSIFRTASMLCLNKPSPLP-QKSPVRSLSKRLLHLP 211
Y ++ ++ I +F A L L KS +R++ + LL P
Sbjct: 207 YY--ETSVVAQFGIKDVFDNAIRAALISRRHLQFWKSHLRNVQRPLLQAP 254
>gi|239915976 RAB19, member RAS oncogene family [Homo sapiens]
Length = 217
Score = 72.0 bits (175), Expect = 4e-13
Identities = 49/168 (29%), Positives = 85/168 (50%), Gaps = 16/168 (9%)
Query: 15 KLVLVGDVQCGKTAMLQVLAKDCYPETYVPTVFENYTA-CLETEEQRVELSLWDTSGSPY 73
K++L+GD GKT ++Q Y ET T+ ++T L+ + ++V++ +WDT+G
Sbjct: 19 KIILIGDSNVGKTCVVQHFKSGVYTETQQNTIGVDFTVRSLDIDGKKVKMQVWDTAGQER 78
Query: 74 YDNVRPLCYSDSDAVLLCFDISRPETVDSALKKWRTEILDY-CPSTRVLLIGCKTDLRTD 132
+ + Y + A ++ +D++R T +S + W EI Y + ++LIG K D
Sbjct: 79 FRTITQSYYRSAHAAIIAYDLTRRSTFES-IPHWIHEIEKYGAANVVIMLIGNKCD---- 133
Query: 133 LSTLMELSHQKQAPISYEQGCAIAKQLGAEIYLEGSAFTSEKSIHSIF 180
L E H + +E C +A++ G LE SA S K+I +F
Sbjct: 134 ---LWEKRH-----VLFEDACTLAEKYGLLAVLETSAKES-KNIEEVF 172
>gi|19923985 RAB3C, member RAS oncogene family [Homo sapiens]
Length = 227
Score = 68.9 bits (167), Expect = 3e-12
Identities = 52/194 (26%), Positives = 97/194 (50%), Gaps = 17/194 (8%)
Query: 15 KLVLVGDVQCGKTAMLQVLAKDCYPETYVPTVFENYTA-CLETEEQRVELSLWDTSGSPY 73
KL+++G+ GKT+ L A D + +V TV ++ + E+R++L +WDT+G
Sbjct: 32 KLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVFKNEKRIKLQIWDTAGQER 91
Query: 74 YDNVRPLCYSDSDAVLLCFDISRPETVDSALKKWRTEILDYC-PSTRVLLIGCKTDLRTD 132
Y + Y + +L +DI+ E+ +A++ W T+I Y + +V+L+G K D+
Sbjct: 92 YRTITTAYYRGAMGFILMYDITNEESF-NAVQDWSTQIKTYSWDNAQVILVGNKCDM--- 147
Query: 133 LSTLMELSHQKQAPISYEQGCAIAKQLGAEIYLEGSAFTSEKSIHSIFRTASMLCLNKPS 192
+ + IS E+G + +QLG E + E SA + + R ++C +K S
Sbjct: 148 ---------EDERVISTERGQHLGEQLGFE-FFETSAKDNINVKQTFERLVDIIC-DKMS 196
Query: 193 PLPQKSPVRSLSKR 206
+ P + +K+
Sbjct: 197 ESLETDPAITAAKQ 210
>gi|106507164 RAB12, member RAS oncogene family [Homo sapiens]
Length = 244
Score = 68.9 bits (167), Expect = 3e-12
Identities = 43/170 (25%), Positives = 83/170 (48%), Gaps = 15/170 (8%)
Query: 2 KERRAPQPVVARCKLVLVGDVQCGKTAMLQVLAKDCYPETYVPTVFENYTA-CLETEEQR 60
+ ++ P+P + +++++G GKT++++ D + E TV ++ +E ++
Sbjct: 31 RRKQPPRPADFKLQVIIIGSRGVGKTSLMERFTDDTFCEACKSTVGVDFKIKTVELRGKK 90
Query: 61 VELSLWDTSGSPYYDNVRPLCYSDSDAVLLCFDISRPETVDSALKKWRTEILDYC-PSTR 119
+ L +WDT+G ++++ Y + ++L +DI++ ET D L KW I Y
Sbjct: 91 IRLQIWDTAGQERFNSITSAYYRSAKGIILVYDITKKETFDD-LPKWMKMIDKYASEDAE 149
Query: 120 VLLIGCKTDLRTDLSTLMELSHQKQAPISYEQGCAIAKQLGAEIYLEGSA 169
+LL+G K D TD I+ +QG A+Q+ + E SA
Sbjct: 150 LLLVGNKLDCETD------------REITRQQGEKFAQQITGMRFCEASA 187
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.132 0.391
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,957,671
Number of Sequences: 37866
Number of extensions: 380796
Number of successful extensions: 1328
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 155
Number of HSP's successfully gapped in prelim test: 41
Number of HSP's that attempted gapping in prelim test: 1089
Number of HSP's gapped (non-prelim): 200
length of query: 232
length of database: 18,247,518
effective HSP length: 99
effective length of query: 133
effective length of database: 14,498,784
effective search space: 1928338272
effective search space used: 1928338272
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.