BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|7657498 MAPK/MAK/MRK overlapping kinase [Homo sapiens] (419 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|7657498 MAPK/MAK/MRK overlapping kinase [Homo sapiens] 855 0.0 gi|27477122 intestinal cell kinase [Homo sapiens] 239 3e-63 gi|7662388 intestinal cell kinase [Homo sapiens] 239 3e-63 gi|11496279 male germ cell-associated kinase [Homo sapiens] 226 3e-59 gi|83367069 cyclin-dependent kinase-like 5 [Homo sapiens] 176 3e-44 gi|4507281 cyclin-dependent kinase-like 5 [Homo sapiens] 176 3e-44 gi|4557439 cyclin-dependent kinase 3 [Homo sapiens] 172 4e-43 gi|89903018 cell cycle related kinase isoform 3 [Homo sapiens] 166 5e-41 gi|166064027 cyclin-dependent kinase-like 3 isoform 1 [Homo sapi... 165 6e-41 gi|166064025 cyclin-dependent kinase-like 3 isoform 2 [Homo sapi... 165 6e-41 gi|37595545 PCTAIRE protein kinase 2 [Homo sapiens] 164 1e-40 gi|4502709 cell division cycle 2 isoform 1 [Homo sapiens] 163 2e-40 gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens] 163 2e-40 gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens] 163 2e-40 gi|16936528 cyclin-dependent kinase 2 isoform 1 [Homo sapiens] 163 2e-40 gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof... 162 4e-40 gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isof... 162 4e-40 gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof... 162 4e-40 gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof... 162 4e-40 gi|16332360 cell division cycle 2-like 1 (PITSLRE proteins) isof... 162 4e-40 gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isof... 162 4e-40 gi|195927041 cell division cycle 2 isoform 3 [Homo sapiens] 162 7e-40 gi|37596297 cyclin-dependent kinase-like 1 [Homo sapiens] 161 1e-39 gi|223718134 cyclin-dependent kinase 6 [Homo sapiens] 159 3e-39 gi|4502741 cyclin-dependent kinase 6 [Homo sapiens] 159 3e-39 gi|91718899 mitogen-activated protein kinase 3 isoform 1 [Homo s... 159 4e-39 gi|20986497 mitogen-activated protein kinase 7 isoform 1 [Homo s... 159 4e-39 gi|209529736 mitogen-activated protein kinase 7 isoform 1 [Homo ... 159 4e-39 gi|209529734 mitogen-activated protein kinase 7 isoform 1 [Homo ... 159 4e-39 gi|95147356 mitogen-activated protein kinase 15 [Homo sapiens] 158 8e-39 >gi|7657498 MAPK/MAK/MRK overlapping kinase [Homo sapiens] Length = 419 Score = 855 bits (2210), Expect = 0.0 Identities = 419/419 (100%), Positives = 419/419 (100%) Query: 1 MKNYKAIGKIGEGTFSEVMKMQSLRDGNYYACKQMKQRFESIEQVNNLREIQALRRLNPH 60 MKNYKAIGKIGEGTFSEVMKMQSLRDGNYYACKQMKQRFESIEQVNNLREIQALRRLNPH Sbjct: 1 MKNYKAIGKIGEGTFSEVMKMQSLRDGNYYACKQMKQRFESIEQVNNLREIQALRRLNPH 60 Query: 61 PNILMLHEVVFDRKSGSLALICELMDMNIYELIRGRRYPLSEKKIMHYMYQLCKSLDHIH 120 PNILMLHEVVFDRKSGSLALICELMDMNIYELIRGRRYPLSEKKIMHYMYQLCKSLDHIH Sbjct: 61 PNILMLHEVVFDRKSGSLALICELMDMNIYELIRGRRYPLSEKKIMHYMYQLCKSLDHIH 120 Query: 121 RNGIFHRDVKPENILIKQDVLKLGDFGSCRSVYSKQPYTEYISTRWYRAPECLLTDGFYT 180 RNGIFHRDVKPENILIKQDVLKLGDFGSCRSVYSKQPYTEYISTRWYRAPECLLTDGFYT Sbjct: 121 RNGIFHRDVKPENILIKQDVLKLGDFGSCRSVYSKQPYTEYISTRWYRAPECLLTDGFYT 180 Query: 181 YKMDLWSAGCVFYEIASLQPLFPGVNELDQISKIHDVIGTPAQKILTKFKQSRAMNFDFP 240 YKMDLWSAGCVFYEIASLQPLFPGVNELDQISKIHDVIGTPAQKILTKFKQSRAMNFDFP Sbjct: 181 YKMDLWSAGCVFYEIASLQPLFPGVNELDQISKIHDVIGTPAQKILTKFKQSRAMNFDFP 240 Query: 241 FKKGSGIPLLTTNLSPQCLSLLHAMVAYDPDERIAAHQALQHPYFQEQRKTEKRALGSHR 300 FKKGSGIPLLTTNLSPQCLSLLHAMVAYDPDERIAAHQALQHPYFQEQRKTEKRALGSHR Sbjct: 241 FKKGSGIPLLTTNLSPQCLSLLHAMVAYDPDERIAAHQALQHPYFQEQRKTEKRALGSHR 300 Query: 301 KAGFPEHPVAPEPLSNSCQISKEGRKQKQSLKQEEDRPKRRGPAYVMELPKLKLSGVVRL 360 KAGFPEHPVAPEPLSNSCQISKEGRKQKQSLKQEEDRPKRRGPAYVMELPKLKLSGVVRL Sbjct: 301 KAGFPEHPVAPEPLSNSCQISKEGRKQKQSLKQEEDRPKRRGPAYVMELPKLKLSGVVRL 360 Query: 361 SSYSSPTLQSVLGSGTNGRVPVLRPLKCIPASKKTDPQKDLKPAPQQCRLPTIVRKGGR 419 SSYSSPTLQSVLGSGTNGRVPVLRPLKCIPASKKTDPQKDLKPAPQQCRLPTIVRKGGR Sbjct: 361 SSYSSPTLQSVLGSGTNGRVPVLRPLKCIPASKKTDPQKDLKPAPQQCRLPTIVRKGGR 419 >gi|27477122 intestinal cell kinase [Homo sapiens] Length = 632 Score = 239 bits (611), Expect = 3e-63 Identities = 135/345 (39%), Positives = 204/345 (59%), Gaps = 19/345 (5%) Query: 1 MKNYKAIGKIGEGTFSEVMKMQSLRDGNYYACKQMKQRFESIEQVNNLREIQALRRLNPH 60 M Y I ++G+GT+ V+ +S+ G A K+MK++F S E+ NLRE+++L++LN H Sbjct: 1 MNRYTTIRQLGDGTYGSVLLGRSIESGELIAIKKMKRKFYSWEECMNLREVKSLKKLN-H 59 Query: 61 PNILMLHEVVFDRKSGSLALICELMDMNIYELIRGRRYPLSEKKIMHYMYQLCKSLDHIH 120 N++ L EV+ R++ L I E M N+Y+LI+ R E I + MYQ+ + L IH Sbjct: 60 ANVVKLKEVI--RENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIH 117 Query: 121 RNGIFHRDVKPENIL-IKQDVLKLGDFGSCRSVYSKQPYTEYISTRWYRAPECLLTDGFY 179 ++G FHRD+KPEN+L + +++K+ DFG R + SK PYT+Y+STRWYRAPE LL Y Sbjct: 118 KHGFFHRDLKPENLLCMGPELVKIADFGLAREIRSKPPYTDYVSTRWYRAPEVLLRSTNY 177 Query: 180 TYKMDLWSAGCVFYEIASLQPLFPGVNELDQISKIHDVIGTPAQKILTK-FKQSRAMNFD 238 + +D+W+ GC+ E+ +L+PLFPG +E+D I KI V+GTP + + ++ S AMNF Sbjct: 178 SSPIDVWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGTPKKTDWPEGYQLSSAMNFR 237 Query: 239 FPFKKGSGIPLLTTNLSPQCLSLLHAMVAYDPDERIAAHQALQHPYF----------QEQ 288 +P + + L N S + + LL M+ +DP +R A QAL++PYF Q Sbjct: 238 WPQCVPNNLKTLIPNASSEAVQLLRDMLQWDPKKRPTASQALRYPYFQVGHPLGSTTQNL 297 Query: 289 RKTEKRALGSHRKAGFPEH----PVAPEPLSNSCQISKEGRKQKQ 329 + +EK G KAG P + P A P +IS + Q Sbjct: 298 QDSEKPQKGILEKAGPPPYIKPVPPAQPPAKPHTRISSRQHQASQ 342 >gi|7662388 intestinal cell kinase [Homo sapiens] Length = 632 Score = 239 bits (611), Expect = 3e-63 Identities = 135/345 (39%), Positives = 204/345 (59%), Gaps = 19/345 (5%) Query: 1 MKNYKAIGKIGEGTFSEVMKMQSLRDGNYYACKQMKQRFESIEQVNNLREIQALRRLNPH 60 M Y I ++G+GT+ V+ +S+ G A K+MK++F S E+ NLRE+++L++LN H Sbjct: 1 MNRYTTIRQLGDGTYGSVLLGRSIESGELIAIKKMKRKFYSWEECMNLREVKSLKKLN-H 59 Query: 61 PNILMLHEVVFDRKSGSLALICELMDMNIYELIRGRRYPLSEKKIMHYMYQLCKSLDHIH 120 N++ L EV+ R++ L I E M N+Y+LI+ R E I + MYQ+ + L IH Sbjct: 60 ANVVKLKEVI--RENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIH 117 Query: 121 RNGIFHRDVKPENIL-IKQDVLKLGDFGSCRSVYSKQPYTEYISTRWYRAPECLLTDGFY 179 ++G FHRD+KPEN+L + +++K+ DFG R + SK PYT+Y+STRWYRAPE LL Y Sbjct: 118 KHGFFHRDLKPENLLCMGPELVKIADFGLAREIRSKPPYTDYVSTRWYRAPEVLLRSTNY 177 Query: 180 TYKMDLWSAGCVFYEIASLQPLFPGVNELDQISKIHDVIGTPAQKILTK-FKQSRAMNFD 238 + +D+W+ GC+ E+ +L+PLFPG +E+D I KI V+GTP + + ++ S AMNF Sbjct: 178 SSPIDVWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGTPKKTDWPEGYQLSSAMNFR 237 Query: 239 FPFKKGSGIPLLTTNLSPQCLSLLHAMVAYDPDERIAAHQALQHPYF----------QEQ 288 +P + + L N S + + LL M+ +DP +R A QAL++PYF Q Sbjct: 238 WPQCVPNNLKTLIPNASSEAVQLLRDMLQWDPKKRPTASQALRYPYFQVGHPLGSTTQNL 297 Query: 289 RKTEKRALGSHRKAGFPEH----PVAPEPLSNSCQISKEGRKQKQ 329 + +EK G KAG P + P A P +IS + Q Sbjct: 298 QDSEKPQKGILEKAGPPPYIKPVPPAQPPAKPHTRISSRQHQASQ 342 >gi|11496279 male germ cell-associated kinase [Homo sapiens] Length = 623 Score = 226 bits (576), Expect = 3e-59 Identities = 116/288 (40%), Positives = 183/288 (63%), Gaps = 5/288 (1%) Query: 1 MKNYKAIGKIGEGTFSEVMKMQSLRDGNYYACKQMKQRFESIEQVNNLREIQALRRLNPH 60 M Y + ++G+GT+ V+ +S G A K+MK++F S ++ NLRE+++L++LN H Sbjct: 1 MNRYTTMRQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECMNLREVKSLKKLN-H 59 Query: 61 PNILMLHEVVFDRKSGSLALICELMDMNIYELIRGRRYPLSEKKIMHYMYQLCKSLDHIH 120 N++ L EV+ R++ L I E M N+Y+L++ R E I + MYQ+ + L IH Sbjct: 60 ANVIKLKEVI--RENDHLYFIFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQGLAFIH 117 Query: 121 RNGIFHRDVKPENIL-IKQDVLKLGDFGSCRSVYSKQPYTEYISTRWYRAPECLLTDGFY 179 ++G FHRD+KPEN+L + +++K+ DFG R + S+ PYT+Y+STRWYRAPE LL Y Sbjct: 118 KHGFFHRDMKPENLLCMGPELVKIADFGLARELRSQPPYTDYVSTRWYRAPEVLLRSSVY 177 Query: 180 TYKMDLWSAGCVFYEIASLQPLFPGVNELDQISKIHDVIGTPAQKILTK-FKQSRAMNFD 238 + +D+W+ G + E+ L+PLFPG +E+D+I KI V+GTP + + ++ + +MNF Sbjct: 178 SSPIDVWAVGSIMAELYMLRPLFPGTSEVDEIFKICQVLGTPKKSDWPEGYQLASSMNFR 237 Query: 239 FPFKKGSGIPLLTTNLSPQCLSLLHAMVAYDPDERIAAHQALQHPYFQ 286 FP + L N S + + L+ M+ +DP +R A QAL+HPYFQ Sbjct: 238 FPQCVPINLKTLIPNASNEAIQLMTEMLNWDPKKRPTASQALKHPYFQ 285 >gi|83367069 cyclin-dependent kinase-like 5 [Homo sapiens] Length = 1030 Score = 176 bits (447), Expect = 3e-44 Identities = 120/349 (34%), Positives = 180/349 (51%), Gaps = 26/349 (7%) Query: 1 MKNYKAIGKIGEGTFSEVMKMQSLRDGNYYACKQMKQRFESIE-QVNNLREIQALRRLNP 59 M ++ +G +GEG + V+K + A K+ K E+ E + LRE++ LR L Sbjct: 10 MNKFEILGVVGEGAYGVVLKCRHKETHEIVAIKKFKDSEENEEVKETTLRELKMLRTLKQ 69 Query: 60 HPNILMLHEVVFDRKSGSLALICELMDMNIYELIRGRRYPLSEKKIMHYMYQLCKSLDHI 119 NI+ L E R+ G L L+ E ++ N+ EL+ + +K+ Y+YQL K++ Sbjct: 70 E-NIVELKEAF--RRRGKLYLVFEYVEKNMLELLEEMPNGVPPEKVKSYIYQLIKAIHWC 126 Query: 120 HRNGIFHRDVKPENILIK-QDVLKLGDFGSCRSVY--SKQPYTEYISTRWYRAPECLLTD 176 H+N I HRD+KPEN+LI DVLKL DFG R++ + YTEY++TRWYR+PE LL Sbjct: 127 HKNDIVHRDIKPENLLISHNDVLKLCDFGFARNLSEGNNANYTEYVATRWYRSPE-LLLG 185 Query: 177 GFYTYKMDLWSAGCVFYEIASLQPLFPGVNELDQISKIHDVIG-TPAQKILTKFKQSRAM 235 Y +D+WS GC+ E++ QPLFPG +E+DQ+ I V+G P++++ + R Sbjct: 186 APYGKSVDMWSVGCILGELSDGQPLFPGESEIDQLFTIQKVLGPLPSEQMKLFYSNPRFH 245 Query: 236 NFDFPF--------KKGSGIPLLTTNLSPQCLSLLHAMVAYDPDERIAAHQALQHPYFQE 287 FP ++ GI L+ L L+ ++ DP +R Q L HP FQ Sbjct: 246 GLRFPAVNHPQSLERRYLGI------LNSVLLDLMKNLLKLDPADRYLTEQCLNHPTFQT 299 Query: 288 QRKTEKRALGSHRKAGFPEHPVAPEPLSNSCQISKEGRKQKQSLKQEED 336 QR ++ S ++ P H V LSN Q K Q +D Sbjct: 300 QRLLDRSPSRSAKRK--PYH-VESSTLSNRNQAGKSTALQSHHRSNSKD 345 >gi|4507281 cyclin-dependent kinase-like 5 [Homo sapiens] Length = 1030 Score = 176 bits (447), Expect = 3e-44 Identities = 120/349 (34%), Positives = 180/349 (51%), Gaps = 26/349 (7%) Query: 1 MKNYKAIGKIGEGTFSEVMKMQSLRDGNYYACKQMKQRFESIE-QVNNLREIQALRRLNP 59 M ++ +G +GEG + V+K + A K+ K E+ E + LRE++ LR L Sbjct: 10 MNKFEILGVVGEGAYGVVLKCRHKETHEIVAIKKFKDSEENEEVKETTLRELKMLRTLKQ 69 Query: 60 HPNILMLHEVVFDRKSGSLALICELMDMNIYELIRGRRYPLSEKKIMHYMYQLCKSLDHI 119 NI+ L E R+ G L L+ E ++ N+ EL+ + +K+ Y+YQL K++ Sbjct: 70 E-NIVELKEAF--RRRGKLYLVFEYVEKNMLELLEEMPNGVPPEKVKSYIYQLIKAIHWC 126 Query: 120 HRNGIFHRDVKPENILIK-QDVLKLGDFGSCRSVY--SKQPYTEYISTRWYRAPECLLTD 176 H+N I HRD+KPEN+LI DVLKL DFG R++ + YTEY++TRWYR+PE LL Sbjct: 127 HKNDIVHRDIKPENLLISHNDVLKLCDFGFARNLSEGNNANYTEYVATRWYRSPE-LLLG 185 Query: 177 GFYTYKMDLWSAGCVFYEIASLQPLFPGVNELDQISKIHDVIG-TPAQKILTKFKQSRAM 235 Y +D+WS GC+ E++ QPLFPG +E+DQ+ I V+G P++++ + R Sbjct: 186 APYGKSVDMWSVGCILGELSDGQPLFPGESEIDQLFTIQKVLGPLPSEQMKLFYSNPRFH 245 Query: 236 NFDFPF--------KKGSGIPLLTTNLSPQCLSLLHAMVAYDPDERIAAHQALQHPYFQE 287 FP ++ GI L+ L L+ ++ DP +R Q L HP FQ Sbjct: 246 GLRFPAVNHPQSLERRYLGI------LNSVLLDLMKNLLKLDPADRYLTEQCLNHPTFQT 299 Query: 288 QRKTEKRALGSHRKAGFPEHPVAPEPLSNSCQISKEGRKQKQSLKQEED 336 QR ++ S ++ P H V LSN Q K Q +D Sbjct: 300 QRLLDRSPSRSAKRK--PYH-VESSTLSNRNQAGKSTALQSHHRSNSKD 345 >gi|4557439 cyclin-dependent kinase 3 [Homo sapiens] Length = 305 Score = 172 bits (437), Expect = 4e-43 Identities = 105/292 (35%), Positives = 162/292 (55%), Gaps = 13/292 (4%) Query: 1 MKNYKAIGKIGEGTFSEVMKMQSLRDGNYYACKQMKQRFESIEQVNN--LREIQALRRLN 58 M ++ + KIGEGT+ V K ++ G A K+++ E +E V + +REI L+ L Sbjct: 1 MDMFQKVEKIGEGTYGVVYKAKNRETGQLVALKKIRLDLE-MEGVPSTAIREISLLKELK 59 Query: 59 PHPNILMLHEVVFDRKSGSLALICELMDMNIYELIR---GRRYPLSEKKIMHYMYQLCKS 115 HPNI+ L +VV + + L L+ E + ++ + + G PL I Y++QL + Sbjct: 60 -HPNIVRLLDVVHNERK--LYLVFEFLSQDLKKYMDSTPGSELPLH--LIKSYLFQLLQG 114 Query: 116 LDHIHRNGIFHRDVKPENILIKQ-DVLKLGDFGSCRSV-YSKQPYTEYISTRWYRAPECL 173 + H + + HRD+KP+N+LI + +KL DFG R+ + YT + T WYRAPE L Sbjct: 115 VSFCHSHRVIHRDLKPQNLLINELGAIKLADFGLARAFGVPLRTYTHEVVTLWYRAPEIL 174 Query: 174 LTDGFYTYKMDLWSAGCVFYEIASLQPLFPGVNELDQISKIHDVIGTPAQKILTKFKQSR 233 L FYT +D+WS GC+F E+ + + LFPG +E+DQ+ +I ++GTP++ Q Sbjct: 175 LGSKFYTTAVDIWSIGCIFAEMVTRKALFPGDSEIDQLFRIFRMLGTPSEDTWPGVTQLP 234 Query: 234 AMNFDFPFKKGSGIPLLTTNLSPQCLSLLHAMVAYDPDERIAAHQALQHPYF 285 FP G+ + NL P+ LL ++ YDP +RI A AL HPYF Sbjct: 235 DYKGSFPKWTRKGLEEIVPNLEPEGRDLLMQLLQYDPSQRITAKTALAHPYF 286 >gi|89903018 cell cycle related kinase isoform 3 [Homo sapiens] Length = 346 Score = 166 bits (419), Expect = 5e-41 Identities = 103/291 (35%), Positives = 157/291 (53%), Gaps = 9/291 (3%) Query: 1 MKNYKAIGKIGEGTFSEVMKMQSLRDGNYYACKQMK-QRFESIEQVNNLREIQALRRLNP 59 M Y +G+IGEG V K + + G A K++ +R E LREI+AL+ + Sbjct: 1 MDQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGFPNQALREIKALQEMED 60 Query: 60 HPNILMLHEVVFDRKSGSLALICELMDMNIYELIRGRRYPLSEKKIMHYMYQLCKSLDHI 119 + ++ L + VF G L E M ++ E++R + PL++ ++ Y+ L K + Sbjct: 61 NQYVVQL-KAVFPH-GGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQMLLKGVAFC 118 Query: 120 HRNGIFHRDVKPENILIKQD-VLKLGDFGSCR--SVYSKQPYTEYISTRWYRAPECLLTD 176 H N I HRD+KP N+LI LK+ DFG R S + YT ++TRWYRAPE L Sbjct: 119 HANNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATRWYRAPELLYGA 178 Query: 177 GFYTYKMDLWSAGCVFYEIASLQPLFPGVNELDQISKIHDVIGTPAQKILTKFKQSRAMN 236 Y +DLWS GC+ E+ + PLFPG N+++Q+ + ++GTP ++ + + N Sbjct: 179 RQYDQGVDLWSVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQVWPELTELPDYN 238 Query: 237 FDFPFKKGSGIPL--LTTNLSPQCLSLLHAMVAYDPDERIAAHQALQHPYF 285 FK+ +PL + ++SPQ L LL + Y P +RIAA +AL H YF Sbjct: 239 -KISFKEQVPMPLEEVLPDVSPQALDLLGQFLLYPPHQRIAASKALLHQYF 288 >gi|166064027 cyclin-dependent kinase-like 3 isoform 1 [Homo sapiens] Length = 592 Score = 165 bits (418), Expect = 6e-41 Identities = 110/362 (30%), Positives = 180/362 (49%), Gaps = 38/362 (10%) Query: 1 MKNYKAIGKIGEGTFSEVMKMQSLRDGNYYACKQMKQRFESIEQVNNLREIQALRRLNPH 60 M+ Y+ +GK+GEG++ VMK + G A K +R E +REI+ L++ + H Sbjct: 1 MEMYETLGKVGEGSYGTVMKCKHKNTGQIVAIKIFYERPEQSVNKIAMREIKFLKQFH-H 59 Query: 61 PNILMLHEVVFDRKSGSLALICELMDMNIYELIRGRRYPLSEKKIMHYMYQLCKSLDHIH 120 N++ L EV +K + L+ E +D + + ++ + L K++ Y++Q+ +++D++H Sbjct: 60 ENLVNLIEVFRQKKK--IHLVFEFIDHTVLDELQHYCHGLESKRLRKYLFQILRAIDYLH 117 Query: 121 RNGIFHRDVKPENILIKQD-VLKLGDFGSCRSVYSKQP-YTEYISTRWYRAPECLLTDGF 178 N I HRD+KPENIL+ Q + KL DFG R++ + YT+Y++TRWYRAPE +L D Sbjct: 118 SNNIIHRDIKPENILVSQSGITKLCDFGFARTLAAPGDIYTDYVATRWYRAPELVLKDTS 177 Query: 179 YTYKMDLWSAGCVFYEIASLQPLFPGVNELDQISKIHDVIGTPAQKILTKFKQSRAMNFD 238 Y +D+W+ GC+ E+A+ P P ++LD + KI +G + + F +S Sbjct: 178 YGKPVDIWALGCMIIEMATGNPYLPSSSDLDLLHKIVLKVGNLSPHLQNIFSKS------ 231 Query: 239 FPFKKGSGIPLLT---------TNLSPQCLSLLHAMVAYDPDERIAAHQALQHPYFQEQR 289 P G +P + L+ ++HA + DP +RI++ L H YF Sbjct: 232 -PIFAGVVLPQVQHPKNARKKYPKLNGLLADIVHACLQIDPADRISSSDLLHHEYFTRDG 290 Query: 290 KTEKRALGSHRKAGFPEHPVAPEPLSNSCQISKEGR--KQKQSLKQEEDRPKRRGPAYVM 347 EK PE + Q +K K K+S K+ E R R Y Sbjct: 291 FIEK---------------FMPELKAKLLQEAKVNSLIKPKESSKENELRKDERKTVYTN 335 Query: 348 EL 349 L Sbjct: 336 TL 337 >gi|166064025 cyclin-dependent kinase-like 3 isoform 2 [Homo sapiens] Length = 455 Score = 165 bits (418), Expect = 6e-41 Identities = 110/362 (30%), Positives = 180/362 (49%), Gaps = 38/362 (10%) Query: 1 MKNYKAIGKIGEGTFSEVMKMQSLRDGNYYACKQMKQRFESIEQVNNLREIQALRRLNPH 60 M+ Y+ +GK+GEG++ VMK + G A K +R E +REI+ L++ + H Sbjct: 1 MEMYETLGKVGEGSYGTVMKCKHKNTGQIVAIKIFYERPEQSVNKIAMREIKFLKQFH-H 59 Query: 61 PNILMLHEVVFDRKSGSLALICELMDMNIYELIRGRRYPLSEKKIMHYMYQLCKSLDHIH 120 N++ L EV +K + L+ E +D + + ++ + L K++ Y++Q+ +++D++H Sbjct: 60 ENLVNLIEVFRQKKK--IHLVFEFIDHTVLDELQHYCHGLESKRLRKYLFQILRAIDYLH 117 Query: 121 RNGIFHRDVKPENILIKQD-VLKLGDFGSCRSVYSKQP-YTEYISTRWYRAPECLLTDGF 178 N I HRD+KPENIL+ Q + KL DFG R++ + YT+Y++TRWYRAPE +L D Sbjct: 118 SNNIIHRDIKPENILVSQSGITKLCDFGFARTLAAPGDIYTDYVATRWYRAPELVLKDTS 177 Query: 179 YTYKMDLWSAGCVFYEIASLQPLFPGVNELDQISKIHDVIGTPAQKILTKFKQSRAMNFD 238 Y +D+W+ GC+ E+A+ P P ++LD + KI +G + + F +S Sbjct: 178 YGKPVDIWALGCMIIEMATGNPYLPSSSDLDLLHKIVLKVGNLSPHLQNIFSKS------ 231 Query: 239 FPFKKGSGIPLLT---------TNLSPQCLSLLHAMVAYDPDERIAAHQALQHPYFQEQR 289 P G +P + L+ ++HA + DP +RI++ L H YF Sbjct: 232 -PIFAGVVLPQVQHPKNARKKYPKLNGLLADIVHACLQIDPADRISSSDLLHHEYFTRDG 290 Query: 290 KTEKRALGSHRKAGFPEHPVAPEPLSNSCQISKEGR--KQKQSLKQEEDRPKRRGPAYVM 347 EK PE + Q +K K K+S K+ E R R Y Sbjct: 291 FIEK---------------FMPELKAKLLQEAKVNSLIKPKESSKENELRKDERKTVYTN 335 Query: 348 EL 349 L Sbjct: 336 TL 337 >gi|37595545 PCTAIRE protein kinase 2 [Homo sapiens] Length = 523 Score = 164 bits (416), Expect = 1e-40 Identities = 95/290 (32%), Positives = 162/290 (55%), Gaps = 8/290 (2%) Query: 1 MKNYKAIGKIGEGTFSEVMKMQSLRDGNYYACKQMKQRFESIEQVNNLREIQALRRLNPH 60 M+ Y + K+GEGT++ V K +S N A K+++ E +RE+ L+ L H Sbjct: 189 METYIKLEKLGEGTYATVYKGRSKLTENLVALKEIRLEHEEGAPCTAIREVSLLKDLK-H 247 Query: 61 PNILMLHEVVFDRKSGSLALICELMDMNIYELIRGRRYPLSEKKIMHYMYQLCKSLDHIH 120 NI+ LH++V KS L L+ E +D ++ + + +S + ++YQ+ + L + H Sbjct: 248 ANIVTLHDIVHTDKS--LTLVFEYLDKDLKQYMDDCGNIMSMHNVKLFLYQILRGLAYCH 305 Query: 121 RNGIFHRDVKPENILIKQD-VLKLGDFGSCR--SVYSKQPYTEYISTRWYRAPECLLTDG 177 R + HRD+KP+N+LI + LKL DFG R SV +K Y+ + T WYR P+ LL Sbjct: 306 RRKVLHRDLKPQNLLINEKGELKLADFGLARAKSVPTKT-YSNEVVTLWYRPPDVLLGSS 364 Query: 178 FYTYKMDLWSAGCVFYEIASLQPLFPGVNELDQISKIHDVIGTPAQKILTKFKQSRAM-N 236 Y+ ++D+W GC+F+E+AS +PLFPG D++ I ++GTP+Q+ + N Sbjct: 365 EYSTQIDMWGVGCIFFEMASGRPLFPGSTVEDELHLIFRLLGTPSQETWPGISSNEEFKN 424 Query: 237 FDFPFKKGSGIPLLTTNLSPQCLSLLHAMVAYDPDERIAAHQALQHPYFQ 286 ++FP K + L + + L+ + Y+ +R++A +A++H YF+ Sbjct: 425 YNFPKYKPQPLINHAPRLDSEGIELITKFLQYESKKRVSAEEAMKHVYFR 474 >gi|4502709 cell division cycle 2 isoform 1 [Homo sapiens] Length = 297 Score = 163 bits (413), Expect = 2e-40 Identities = 103/295 (34%), Positives = 159/295 (53%), Gaps = 14/295 (4%) Query: 1 MKNYKAIGKIGEGTFSEVMKMQSLRDGNYYACKQMKQRFESIEQ---VNNLREIQALRRL 57 M++Y I KIGEGT+ V K + G A K++ R ES E+ +REI L+ L Sbjct: 1 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKI--RLESEEEGVPSTAIREISLLKEL 58 Query: 58 NPHPNILMLHEVVFDRKSGSLALICELMDMNI---YELIRGRRYPLSEKKIMHYMYQLCK 114 HPNI+ L +V+ + L LI E + M++ + I +Y + + Y+YQ+ + Sbjct: 59 R-HPNIVSLQDVLM--QDSRLYLIFEFLSMDLKKYLDSIPPGQY-MDSSLVKSYLYQILQ 114 Query: 115 SLDHIHRNGIFHRDVKPENILIK-QDVLKLGDFGSCRSV-YSKQPYTEYISTRWYRAPEC 172 + H + HRD+KP+N+LI + +KL DFG R+ + YT + T WYR+PE Sbjct: 115 GIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEV 174 Query: 173 LLTDGFYTYKMDLWSAGCVFYEIASLQPLFPGVNELDQISKIHDVIGTPAQKILTKFKQS 232 LL Y+ +D+WS G +F E+A+ +PLF G +E+DQ+ +I +GTP ++ + + Sbjct: 175 LLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESL 234 Query: 233 RAMNFDFPFKKGSGIPLLTTNLSPQCLSLLHAMVAYDPDERIAAHQALQHPYFQE 287 + FP K + NL L LL M+ YDP +RI+ AL HPYF + Sbjct: 235 QDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFND 289 >gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens] Length = 770 Score = 163 bits (413), Expect = 2e-40 Identities = 95/297 (31%), Positives = 162/297 (54%), Gaps = 16/297 (5%) Query: 1 MKNYKAIGKIGEGTFSEVMKMQSLRDGNYYACKQMKQRFESIE-QVNNLREIQALRRLNP 59 ++ ++ + +I EGT+ V + + + A K++K E + +LREI + + Sbjct: 410 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQ- 468 Query: 60 HPNILMLHEVVFDRKSGSLALICELMDMNIYELIRGRRYPLSEKKIMHYMYQLCKSLDHI 119 HPNI+ + E+V + ++ ++ ++ L+ + P ++ M QL + + H+ Sbjct: 469 HPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHL 528 Query: 120 HRNGIFHRDVKPENILIKQ-DVLKLGDFGSCRSVYSK-QPYTEYISTRWYRAPECLLTDG 177 H N I HRD+K N+L+ +LK+GDFG R S + YT + T+WYRAPE LL Sbjct: 529 HDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAK 588 Query: 178 FYTYKMDLWSAGCVFYEIASLQPLFPGVNELDQISKIHDVIGTPAQKILTKFKQ---SRA 234 Y+ +D+WS GC+F E+ + +PLFPG +E+DQI+K+ +GTP++KI + + + Sbjct: 589 EYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKK 648 Query: 235 MNF-DFPF---KKGSGIPLLTTNLSPQCLSLLHAMVAYDPDERIAAHQALQHPYFQE 287 M F + P+ +K G LS Q L++ + Y P RI+A L+H YF+E Sbjct: 649 MTFSEHPYNNLRKRFG-----ALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRE 700 >gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens] Length = 780 Score = 163 bits (413), Expect = 2e-40 Identities = 95/297 (31%), Positives = 162/297 (54%), Gaps = 16/297 (5%) Query: 1 MKNYKAIGKIGEGTFSEVMKMQSLRDGNYYACKQMKQRFESIE-QVNNLREIQALRRLNP 59 ++ ++ + +I EGT+ V + + + A K++K E + +LREI + + Sbjct: 420 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQ- 478 Query: 60 HPNILMLHEVVFDRKSGSLALICELMDMNIYELIRGRRYPLSEKKIMHYMYQLCKSLDHI 119 HPNI+ + E+V + ++ ++ ++ L+ + P ++ M QL + + H+ Sbjct: 479 HPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHL 538 Query: 120 HRNGIFHRDVKPENILIKQ-DVLKLGDFGSCRSVYSK-QPYTEYISTRWYRAPECLLTDG 177 H N I HRD+K N+L+ +LK+GDFG R S + YT + T+WYRAPE LL Sbjct: 539 HDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAK 598 Query: 178 FYTYKMDLWSAGCVFYEIASLQPLFPGVNELDQISKIHDVIGTPAQKILTKFKQ---SRA 234 Y+ +D+WS GC+F E+ + +PLFPG +E+DQI+K+ +GTP++KI + + + Sbjct: 599 EYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKK 658 Query: 235 MNF-DFPF---KKGSGIPLLTTNLSPQCLSLLHAMVAYDPDERIAAHQALQHPYFQE 287 M F + P+ +K G LS Q L++ + Y P RI+A L+H YF+E Sbjct: 659 MTFSEHPYNNLRKRFG-----ALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRE 710 >gi|16936528 cyclin-dependent kinase 2 isoform 1 [Homo sapiens] Length = 298 Score = 163 bits (413), Expect = 2e-40 Identities = 104/299 (34%), Positives = 162/299 (54%), Gaps = 17/299 (5%) Query: 1 MKNYKAIGKIGEGTFSEVMKMQSLRDGNYYACKQMKQRFESIEQVNN--LREIQALRRLN 58 M+N++ + KIGEGT+ V K ++ G A K+++ E+ E V + +REI L+ LN Sbjct: 1 MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTET-EGVPSTAIREISLLKELN 59 Query: 59 PHPNILMLHEVVFDRKSGSLALICELMDMNIYEL-----IRGRRYPLSEKKIMHYMYQLC 113 HPNI+ L +V+ L L+ E + ++ + + G PL I Y++QL Sbjct: 60 -HPNIVKLLDVI--HTENKLYLVFEFLHQDLKKFMDASALTGIPLPL----IKSYLFQLL 112 Query: 114 KSLDHIHRNGIFHRDVKPENILIKQD-VLKLGDFGSCRSV-YSKQPYTEYISTRWYRAPE 171 + L H + + HRD+KP+N+LI + +KL DFG R+ + YT + T WYRAPE Sbjct: 113 QGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPE 172 Query: 172 CLLTDGFYTYKMDLWSAGCVFYEIASLQPLFPGVNELDQISKIHDVIGTPAQKILTKFKQ 231 LL +Y+ +D+WS GC+F E+ + + LFPG +E+DQ+ +I +GTP + + Sbjct: 173 ILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTS 232 Query: 232 SRAMNFDFPFKKGSGIPLLTTNLSPQCLSLLHAMVAYDPDERIAAHQALQHPYFQEQRK 290 FP + L SLL M+ YDP++RI+A AL HP+FQ+ K Sbjct: 233 MPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTK 291 >gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform 9 [Homo sapiens] Length = 771 Score = 162 bits (411), Expect = 4e-40 Identities = 96/297 (32%), Positives = 161/297 (54%), Gaps = 16/297 (5%) Query: 1 MKNYKAIGKIGEGTFSEVMKMQSLRDGNYYACKQMKQRFESIE-QVNNLREIQALRRLNP 59 ++ ++ + +I EGT+ V + + + A K++K E + +LREI + + Sbjct: 411 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQ- 469 Query: 60 HPNILMLHEVVFDRKSGSLALICELMDMNIYELIRGRRYPLSEKKIMHYMYQLCKSLDHI 119 HPNI+ + E+V + ++ ++ ++ L+ + P ++ M QL + + H+ Sbjct: 470 HPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHL 529 Query: 120 HRNGIFHRDVKPENILIKQ-DVLKLGDFGSCRSVYSK-QPYTEYISTRWYRAPECLLTDG 177 H N I HRD+K N+L+ +LK+GDFG R S + YT + T WYRAPE LL Sbjct: 530 HDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAK 589 Query: 178 FYTYKMDLWSAGCVFYEIASLQPLFPGVNELDQISKIHDVIGTPAQKILTKFKQSRA--- 234 Y+ +D+WS GC+F E+ + +PLFPG +E+DQI+K+ +GTP++KI + + A Sbjct: 590 EYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKK 649 Query: 235 MNF-DFPF---KKGSGIPLLTTNLSPQCLSLLHAMVAYDPDERIAAHQALQHPYFQE 287 M F + P+ +K G LS Q L++ + Y P RI+A L+H YF+E Sbjct: 650 MTFSEHPYNNLRKRFG-----ALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRE 701 >gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isoform 8 [Homo sapiens] Length = 780 Score = 162 bits (411), Expect = 4e-40 Identities = 96/297 (32%), Positives = 161/297 (54%), Gaps = 16/297 (5%) Query: 1 MKNYKAIGKIGEGTFSEVMKMQSLRDGNYYACKQMKQRFESIE-QVNNLREIQALRRLNP 59 ++ ++ + +I EGT+ V + + + A K++K E + +LREI + + Sbjct: 420 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQ- 478 Query: 60 HPNILMLHEVVFDRKSGSLALICELMDMNIYELIRGRRYPLSEKKIMHYMYQLCKSLDHI 119 HPNI+ + E+V + ++ ++ ++ L+ + P ++ M QL + + H+ Sbjct: 479 HPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHL 538 Query: 120 HRNGIFHRDVKPENILIKQ-DVLKLGDFGSCRSVYSK-QPYTEYISTRWYRAPECLLTDG 177 H N I HRD+K N+L+ +LK+GDFG R S + YT + T WYRAPE LL Sbjct: 539 HDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAK 598 Query: 178 FYTYKMDLWSAGCVFYEIASLQPLFPGVNELDQISKIHDVIGTPAQKILTKFKQSRA--- 234 Y+ +D+WS GC+F E+ + +PLFPG +E+DQI+K+ +GTP++KI + + A Sbjct: 599 EYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKK 658 Query: 235 MNF-DFPF---KKGSGIPLLTTNLSPQCLSLLHAMVAYDPDERIAAHQALQHPYFQE 287 M F + P+ +K G LS Q L++ + Y P RI+A L+H YF+E Sbjct: 659 MTFSEHPYNNLRKRFG-----ALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRE 710 >gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform 5 [Homo sapiens] Length = 748 Score = 162 bits (411), Expect = 4e-40 Identities = 96/297 (32%), Positives = 161/297 (54%), Gaps = 16/297 (5%) Query: 1 MKNYKAIGKIGEGTFSEVMKMQSLRDGNYYACKQMKQRFESIE-QVNNLREIQALRRLNP 59 ++ ++ + +I EGT+ V + + + A K++K E + +LREI + + Sbjct: 388 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQ- 446 Query: 60 HPNILMLHEVVFDRKSGSLALICELMDMNIYELIRGRRYPLSEKKIMHYMYQLCKSLDHI 119 HPNI+ + E+V + ++ ++ ++ L+ + P ++ M QL + + H+ Sbjct: 447 HPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHL 506 Query: 120 HRNGIFHRDVKPENILIKQ-DVLKLGDFGSCRSVYSK-QPYTEYISTRWYRAPECLLTDG 177 H N I HRD+K N+L+ +LK+GDFG R S + YT + T WYRAPE LL Sbjct: 507 HDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAK 566 Query: 178 FYTYKMDLWSAGCVFYEIASLQPLFPGVNELDQISKIHDVIGTPAQKILTKFKQSRA--- 234 Y+ +D+WS GC+F E+ + +PLFPG +E+DQI+K+ +GTP++KI + + A Sbjct: 567 EYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKK 626 Query: 235 MNF-DFPF---KKGSGIPLLTTNLSPQCLSLLHAMVAYDPDERIAAHQALQHPYFQE 287 M F + P+ +K G LS Q L++ + Y P RI+A L+H YF+E Sbjct: 627 MTFSEHPYNNLRKRFG-----ALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRE 678 >gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform 4 [Homo sapiens] Length = 737 Score = 162 bits (411), Expect = 4e-40 Identities = 96/297 (32%), Positives = 161/297 (54%), Gaps = 16/297 (5%) Query: 1 MKNYKAIGKIGEGTFSEVMKMQSLRDGNYYACKQMKQRFESIE-QVNNLREIQALRRLNP 59 ++ ++ + +I EGT+ V + + + A K++K E + +LREI + + Sbjct: 377 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQ- 435 Query: 60 HPNILMLHEVVFDRKSGSLALICELMDMNIYELIRGRRYPLSEKKIMHYMYQLCKSLDHI 119 HPNI+ + E+V + ++ ++ ++ L+ + P ++ M QL + + H+ Sbjct: 436 HPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHL 495 Query: 120 HRNGIFHRDVKPENILIKQ-DVLKLGDFGSCRSVYSK-QPYTEYISTRWYRAPECLLTDG 177 H N I HRD+K N+L+ +LK+GDFG R S + YT + T WYRAPE LL Sbjct: 496 HDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAK 555 Query: 178 FYTYKMDLWSAGCVFYEIASLQPLFPGVNELDQISKIHDVIGTPAQKILTKFKQSRA--- 234 Y+ +D+WS GC+F E+ + +PLFPG +E+DQI+K+ +GTP++KI + + A Sbjct: 556 EYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKK 615 Query: 235 MNF-DFPF---KKGSGIPLLTTNLSPQCLSLLHAMVAYDPDERIAAHQALQHPYFQE 287 M F + P+ +K G LS Q L++ + Y P RI+A L+H YF+E Sbjct: 616 MTFSEHPYNNLRKRFG-----ALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRE 667 >gi|16332360 cell division cycle 2-like 1 (PITSLRE proteins) isoform 3 [Homo sapiens] Length = 526 Score = 162 bits (411), Expect = 4e-40 Identities = 96/297 (32%), Positives = 161/297 (54%), Gaps = 16/297 (5%) Query: 1 MKNYKAIGKIGEGTFSEVMKMQSLRDGNYYACKQMKQRFESIE-QVNNLREIQALRRLNP 59 ++ ++ + +I EGT+ V + + + A K++K E + +LREI + + Sbjct: 166 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQ- 224 Query: 60 HPNILMLHEVVFDRKSGSLALICELMDMNIYELIRGRRYPLSEKKIMHYMYQLCKSLDHI 119 HPNI+ + E+V + ++ ++ ++ L+ + P ++ M QL + + H+ Sbjct: 225 HPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHL 284 Query: 120 HRNGIFHRDVKPENILIKQ-DVLKLGDFGSCRSVYSK-QPYTEYISTRWYRAPECLLTDG 177 H N I HRD+K N+L+ +LK+GDFG R S + YT + T WYRAPE LL Sbjct: 285 HDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAK 344 Query: 178 FYTYKMDLWSAGCVFYEIASLQPLFPGVNELDQISKIHDVIGTPAQKILTKFKQSRA--- 234 Y+ +D+WS GC+F E+ + +PLFPG +E+DQI+K+ +GTP++KI + + A Sbjct: 345 EYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKK 404 Query: 235 MNF-DFPF---KKGSGIPLLTTNLSPQCLSLLHAMVAYDPDERIAAHQALQHPYFQE 287 M F + P+ +K G LS Q L++ + Y P RI+A L+H YF+E Sbjct: 405 MTFSEHPYNNLRKRFG-----ALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRE 456 >gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isoform 2 [Homo sapiens] Length = 782 Score = 162 bits (411), Expect = 4e-40 Identities = 96/297 (32%), Positives = 161/297 (54%), Gaps = 16/297 (5%) Query: 1 MKNYKAIGKIGEGTFSEVMKMQSLRDGNYYACKQMKQRFESIE-QVNNLREIQALRRLNP 59 ++ ++ + +I EGT+ V + + + A K++K E + +LREI + + Sbjct: 422 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQ- 480 Query: 60 HPNILMLHEVVFDRKSGSLALICELMDMNIYELIRGRRYPLSEKKIMHYMYQLCKSLDHI 119 HPNI+ + E+V + ++ ++ ++ L+ + P ++ M QL + + H+ Sbjct: 481 HPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHL 540 Query: 120 HRNGIFHRDVKPENILIKQ-DVLKLGDFGSCRSVYSK-QPYTEYISTRWYRAPECLLTDG 177 H N I HRD+K N+L+ +LK+GDFG R S + YT + T WYRAPE LL Sbjct: 541 HDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAK 600 Query: 178 FYTYKMDLWSAGCVFYEIASLQPLFPGVNELDQISKIHDVIGTPAQKILTKFKQSRA--- 234 Y+ +D+WS GC+F E+ + +PLFPG +E+DQI+K+ +GTP++KI + + A Sbjct: 601 EYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKK 660 Query: 235 MNF-DFPF---KKGSGIPLLTTNLSPQCLSLLHAMVAYDPDERIAAHQALQHPYFQE 287 M F + P+ +K G LS Q L++ + Y P RI+A L+H YF+E Sbjct: 661 MTFSEHPYNNLRKRFG-----ALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRE 712 >gi|195927041 cell division cycle 2 isoform 3 [Homo sapiens] Length = 297 Score = 162 bits (409), Expect = 7e-40 Identities = 103/295 (34%), Positives = 158/295 (53%), Gaps = 14/295 (4%) Query: 1 MKNYKAIGKIGEGTFSEVMKMQSLRDGNYYACKQMKQRFESIEQ---VNNLREIQALRRL 57 M++Y I KIGEGT+ V K + G A K++ R ES E+ +REI L+ L Sbjct: 1 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKI--RLESEEEGVPSTAIREISLLKEL 58 Query: 58 NPHPNILMLHEVVFDRKSGSLALICELMDMNI---YELIRGRRYPLSEKKIMHYMYQLCK 114 HPNI+ L +V+ + L LI E + M++ + I +Y + + Y+YQ+ + Sbjct: 59 R-HPNIVSLQDVLM--QDSRLYLIFEFLSMDLKKYLDSIPPGQY-MDSSLVKSYLYQILQ 114 Query: 115 SLDHIHRNGIFHRDVKPENILIK-QDVLKLGDFGSCRSV-YSKQPYTEYISTRWYRAPEC 172 + H + HRD+KP+N+LI + +KL DFG R+ + YT T WYR+PE Sbjct: 115 GIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEAITLWYRSPEV 174 Query: 173 LLTDGFYTYKMDLWSAGCVFYEIASLQPLFPGVNELDQISKIHDVIGTPAQKILTKFKQS 232 LL Y+ +D+WS G +F E+A+ +PLF G +E+DQ+ +I +GTP ++ + + Sbjct: 175 LLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESL 234 Query: 233 RAMNFDFPFKKGSGIPLLTTNLSPQCLSLLHAMVAYDPDERIAAHQALQHPYFQE 287 + FP K + NL L LL M+ YDP +RI+ AL HPYF + Sbjct: 235 QDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFND 289 >gi|37596297 cyclin-dependent kinase-like 1 [Homo sapiens] Length = 358 Score = 161 bits (407), Expect = 1e-39 Identities = 110/308 (35%), Positives = 169/308 (54%), Gaps = 24/308 (7%) Query: 1 MKNYKAIGKIGEGTFSEVMKMQSLRDGNYYACKQ-MKQRFESIEQVNNLREIQALRRLNP 59 M+ Y+ IGKIGEG++ V K ++ G A K+ ++ + + + LREI+ L++L Sbjct: 2 MEKYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKKFLESEDDPVIKKIALREIRMLKQLK- 60 Query: 60 HPNILMLHEVVFDRKSGSLALICELMDMNI-YELIRGRRYPLSEKKIMHYMYQLCKSLDH 118 HPN++ L EV R+ L L+ E D + +EL R +R + E + +Q ++++ Sbjct: 61 HPNLVNLLEVF--RRKRRLHLVFEYCDHTVLHELDRYQR-GVPEHLVKSITWQTLQAVNF 117 Query: 119 IHRNGIFHRDVKPENILI-KQDVLKLGDFGSCRSVYSKQPY-TEYISTRWYRAPECLLTD 176 H++ HRDVKPENILI K V+KL DFG R + Y T+Y++TRWYR+PE L+ D Sbjct: 118 CHKHNCIHRDVKPENILITKHSVIKLCDFGFARLLTGPSDYYTDYVATRWYRSPELLVGD 177 Query: 177 GFYTYKMDLWSAGCVFYEIASLQPLFPGVNELDQISKIHDVIGTPAQKILTKFKQSRAMN 236 Y +D+W+ GCVF E+ S PL+PG +++DQ+ I +G ++ + +Q + N Sbjct: 178 TQYGPPVDVWAIGCVFAELLSGVPLWPGKSDVDQLYLIRKTLG----DLIPRHQQVFSTN 233 Query: 237 FDFPFKKGSGIP---------LLTTNLSPQCLSLLHAMVAYDPDERIAAHQALQHPYFQE 287 F G IP L N+S L LL + DP +R+ Q L HPYF+ Sbjct: 234 QYF---SGVKIPDPEDMEPLELKFPNISYPALGLLKGCLHMDPTQRLTCEQLLHHPYFEN 290 Query: 288 QRKTEKRA 295 R+ E A Sbjct: 291 IREIEDLA 298 >gi|223718134 cyclin-dependent kinase 6 [Homo sapiens] Length = 326 Score = 159 bits (403), Expect = 3e-39 Identities = 104/308 (33%), Positives = 166/308 (53%), Gaps = 15/308 (4%) Query: 2 KNYKAIGKIGEGTFSEVMKMQSLRDGN-YYACKQMK-QRFESIEQVNNLREIQALRRLNP 59 + Y+ + +IGEG + +V K + L++G + A K+++ Q E ++ +RE+ LR L Sbjct: 11 QQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIREVAVLRHLET 70 Query: 60 --HPNILMLHEVVF----DRKSGSLALICELMDMNIYELIRGRRYP-LSEKKIMHYMYQL 112 HPN++ L +V DR++ L L+ E +D ++ + P + + I M+QL Sbjct: 71 FEHPNVVRLFDVCTVSRTDRET-KLTLVFEHVDQDLTTYLDKVPEPGVPTETIKDMMFQL 129 Query: 113 CKSLDHIHRNGIFHRDVKPENILIKQD-VLKLGDFGSCRSVYSKQPYTEYISTRWYRAPE 171 + LD +H + + HRD+KP+NIL+ +KL DFG R + T + T WYRAPE Sbjct: 130 LRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQMALTSVVVTLWYRAPE 189 Query: 172 CLLTDGFYTYKMDLWSAGCVFYEIASLQPLFPGVNELDQISKIHDVIGTPAQKILTKFKQ 231 LL + T +DLWS GC+F E+ +PLF G +++DQ+ KI DVIG P ++ + Sbjct: 190 VLLQSSYAT-PVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGEEDWP--RD 246 Query: 232 SRAMNFDFPFKKGSGIPLLTTNLSPQCLSLLHAMVAYDPDERIAAHQALQHPYFQEQRKT 291 F K I T++ LL + ++P +RI+A+ AL HPYFQ+ + Sbjct: 247 VALPRQAFHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYSALSHPYFQDLERC 306 Query: 292 EKRALGSH 299 K L SH Sbjct: 307 -KENLDSH 313 >gi|4502741 cyclin-dependent kinase 6 [Homo sapiens] Length = 326 Score = 159 bits (403), Expect = 3e-39 Identities = 104/308 (33%), Positives = 166/308 (53%), Gaps = 15/308 (4%) Query: 2 KNYKAIGKIGEGTFSEVMKMQSLRDGN-YYACKQMK-QRFESIEQVNNLREIQALRRLNP 59 + Y+ + +IGEG + +V K + L++G + A K+++ Q E ++ +RE+ LR L Sbjct: 11 QQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIREVAVLRHLET 70 Query: 60 --HPNILMLHEVVF----DRKSGSLALICELMDMNIYELIRGRRYP-LSEKKIMHYMYQL 112 HPN++ L +V DR++ L L+ E +D ++ + P + + I M+QL Sbjct: 71 FEHPNVVRLFDVCTVSRTDRET-KLTLVFEHVDQDLTTYLDKVPEPGVPTETIKDMMFQL 129 Query: 113 CKSLDHIHRNGIFHRDVKPENILIKQD-VLKLGDFGSCRSVYSKQPYTEYISTRWYRAPE 171 + LD +H + + HRD+KP+NIL+ +KL DFG R + T + T WYRAPE Sbjct: 130 LRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQMALTSVVVTLWYRAPE 189 Query: 172 CLLTDGFYTYKMDLWSAGCVFYEIASLQPLFPGVNELDQISKIHDVIGTPAQKILTKFKQ 231 LL + T +DLWS GC+F E+ +PLF G +++DQ+ KI DVIG P ++ + Sbjct: 190 VLLQSSYAT-PVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGEEDWP--RD 246 Query: 232 SRAMNFDFPFKKGSGIPLLTTNLSPQCLSLLHAMVAYDPDERIAAHQALQHPYFQEQRKT 291 F K I T++ LL + ++P +RI+A+ AL HPYFQ+ + Sbjct: 247 VALPRQAFHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYSALSHPYFQDLERC 306 Query: 292 EKRALGSH 299 K L SH Sbjct: 307 -KENLDSH 313 >gi|91718899 mitogen-activated protein kinase 3 isoform 1 [Homo sapiens] Length = 379 Score = 159 bits (402), Expect = 4e-39 Identities = 104/357 (29%), Positives = 179/357 (50%), Gaps = 29/357 (8%) Query: 4 YKAIGKIGEGTFSEVMKMQSLRDGNYYACKQMKQRFESIEQVNNLREIQALRRLNPHPNI 63 Y + IGEG + V A K++ LREIQ L R H N+ Sbjct: 42 YTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKISPFEHQTYCQRTLREIQILLRFR-HENV 100 Query: 64 LMLHEVVFDRKSGSLA---LICELMDMNIYELIRGRRYPLSEKKIMHYMYQLCKSLDHIH 120 + + +++ ++ ++ +LM+ ++Y+L++ ++ LS I +++YQ+ + L +IH Sbjct: 101 IGIRDILRASTLEAMRDVYIVQDLMETDLYKLLKSQQ--LSNDHICYFLYQILRGLKYIH 158 Query: 121 RNGIFHRDVKPENILIKQDV-LKLGDFGSCRSVYSKQPYT----EYISTRWYRAPECLLT 175 + HRD+KP N+LI LK+ DFG R + +T EY++TRWYRAPE +L Sbjct: 159 SANVLHRDLKPSNLLINTTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLN 218 Query: 176 DGFYTYKMDLWSAGCVFYEIASLQPLFPGVNELDQISKIHDVIGTPAQKILTKFKQSRAM 235 YT +D+WS GC+ E+ S +P+FPG + LDQ++ I ++G+P+Q+ L +A Sbjct: 219 SKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINMKAR 278 Query: 236 NF--DFPFKKGSGIPLLTTNLSPQCLSLLHAMVAYDPDERIAAHQALQHPYFQEQRKTEK 293 N+ P K L + L LL M+ ++P++RI +AL HPY ++ Sbjct: 279 NYLQSLPSKTKVAWAKLFPKSDSKALDLLDRMLTFNPNKRITVEEALAHPYLEQYYDP-- 336 Query: 294 RALGSHRKAGFPEHPVAPEPLSNSCQISKEGRKQKQSLKQEEDRPKRRGPAYVMELP 350 + PVA EP + + ++ +++ + L +E + G V+E P Sbjct: 337 -----------TDEPVAEEPFTFAMELDDLPKERLKELIFQETARFQPG---VLEAP 379 >gi|20986497 mitogen-activated protein kinase 7 isoform 1 [Homo sapiens] Length = 816 Score = 159 bits (402), Expect = 4e-39 Identities = 92/294 (31%), Positives = 160/294 (54%), Gaps = 15/294 (5%) Query: 4 YKAIGKIGEGTFSEVMKMQSLRDGNYYACKQMKQRFESIEQVNN-LREIQALRRLNPHPN 62 Y+ I IG G + V + G A K++ F+ + LRE++ L+ H N Sbjct: 55 YEIIETIGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKHFK-HDN 113 Query: 63 ILMLHEVVFDR----KSGSLALICELMDMNIYELIRGRRYPLSEKKIMHYMYQLCKSLDH 118 I+ + +++ + S+ ++ +LM+ +++++I + PL+ + + +++YQL + L + Sbjct: 114 IIAIKDILRPTVPYGEFKSVYVVLDLMESDLHQIIHSSQ-PLTLEHVRYFLYQLLRGLKY 172 Query: 119 IHRNGIFHRDVKPENILIKQDV-LKLGDFGSCRSVYSKQP-----YTEYISTRWYRAPEC 172 +H + HRD+KP N+L+ ++ LK+GDFG R + + TEY++TRWYRAPE Sbjct: 173 MHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYRAPEL 232 Query: 173 LLTDGFYTYKMDLWSAGCVFYEIASLQPLFPGVNELDQISKIHDVIGTPAQKILTKFKQS 232 +L+ YT +DLWS GC+F E+ + + LFPG N + Q+ I V+GTP+ ++ Sbjct: 233 MLSLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAE 292 Query: 233 RAMNFDFPFKKGSGIPLLTT--NLSPQCLSLLHAMVAYDPDERIAAHQALQHPY 284 R + +P T Q LSLL M+ ++P RI+A AL+HP+ Sbjct: 293 RVRAYIQSLPPRQPVPWETVYPGADRQALSLLGRMLRFEPSARISAAAALRHPF 346 >gi|209529736 mitogen-activated protein kinase 7 isoform 1 [Homo sapiens] Length = 816 Score = 159 bits (402), Expect = 4e-39 Identities = 92/294 (31%), Positives = 160/294 (54%), Gaps = 15/294 (5%) Query: 4 YKAIGKIGEGTFSEVMKMQSLRDGNYYACKQMKQRFESIEQVNN-LREIQALRRLNPHPN 62 Y+ I IG G + V + G A K++ F+ + LRE++ L+ H N Sbjct: 55 YEIIETIGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKHFK-HDN 113 Query: 63 ILMLHEVVFDR----KSGSLALICELMDMNIYELIRGRRYPLSEKKIMHYMYQLCKSLDH 118 I+ + +++ + S+ ++ +LM+ +++++I + PL+ + + +++YQL + L + Sbjct: 114 IIAIKDILRPTVPYGEFKSVYVVLDLMESDLHQIIHSSQ-PLTLEHVRYFLYQLLRGLKY 172 Query: 119 IHRNGIFHRDVKPENILIKQDV-LKLGDFGSCRSVYSKQP-----YTEYISTRWYRAPEC 172 +H + HRD+KP N+L+ ++ LK+GDFG R + + TEY++TRWYRAPE Sbjct: 173 MHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYRAPEL 232 Query: 173 LLTDGFYTYKMDLWSAGCVFYEIASLQPLFPGVNELDQISKIHDVIGTPAQKILTKFKQS 232 +L+ YT +DLWS GC+F E+ + + LFPG N + Q+ I V+GTP+ ++ Sbjct: 233 MLSLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAE 292 Query: 233 RAMNFDFPFKKGSGIPLLTT--NLSPQCLSLLHAMVAYDPDERIAAHQALQHPY 284 R + +P T Q LSLL M+ ++P RI+A AL+HP+ Sbjct: 293 RVRAYIQSLPPRQPVPWETVYPGADRQALSLLGRMLRFEPSARISAAAALRHPF 346 >gi|209529734 mitogen-activated protein kinase 7 isoform 1 [Homo sapiens] Length = 816 Score = 159 bits (402), Expect = 4e-39 Identities = 92/294 (31%), Positives = 160/294 (54%), Gaps = 15/294 (5%) Query: 4 YKAIGKIGEGTFSEVMKMQSLRDGNYYACKQMKQRFESIEQVNN-LREIQALRRLNPHPN 62 Y+ I IG G + V + G A K++ F+ + LRE++ L+ H N Sbjct: 55 YEIIETIGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKHFK-HDN 113 Query: 63 ILMLHEVVFDR----KSGSLALICELMDMNIYELIRGRRYPLSEKKIMHYMYQLCKSLDH 118 I+ + +++ + S+ ++ +LM+ +++++I + PL+ + + +++YQL + L + Sbjct: 114 IIAIKDILRPTVPYGEFKSVYVVLDLMESDLHQIIHSSQ-PLTLEHVRYFLYQLLRGLKY 172 Query: 119 IHRNGIFHRDVKPENILIKQDV-LKLGDFGSCRSVYSKQP-----YTEYISTRWYRAPEC 172 +H + HRD+KP N+L+ ++ LK+GDFG R + + TEY++TRWYRAPE Sbjct: 173 MHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYRAPEL 232 Query: 173 LLTDGFYTYKMDLWSAGCVFYEIASLQPLFPGVNELDQISKIHDVIGTPAQKILTKFKQS 232 +L+ YT +DLWS GC+F E+ + + LFPG N + Q+ I V+GTP+ ++ Sbjct: 233 MLSLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAE 292 Query: 233 RAMNFDFPFKKGSGIPLLTT--NLSPQCLSLLHAMVAYDPDERIAAHQALQHPY 284 R + +P T Q LSLL M+ ++P RI+A AL+HP+ Sbjct: 293 RVRAYIQSLPPRQPVPWETVYPGADRQALSLLGRMLRFEPSARISAAAALRHPF 346 >gi|95147356 mitogen-activated protein kinase 15 [Homo sapiens] Length = 544 Score = 158 bits (400), Expect = 8e-39 Identities = 97/297 (32%), Positives = 156/297 (52%), Gaps = 12/297 (4%) Query: 1 MKNYKAIGKIGEGTFSEVMKMQSLRDGNYYACKQMKQRF-ESIEQVNNLREIQALRRLNP 59 ++ Y ++G+G + V K R G A K++ F + + REI L+ Sbjct: 10 VRRYLLRRQLGQGAYGIVWKAVDRRTGEVVAIKKIFDAFRDKTDAQRTFREITLLQEFGD 69 Query: 60 HPNILMLHEVVFDRKSGSLALICELMDMNIYELIRGRRYPLSEKKIMHYMYQLCKSLDHI 119 HPNI+ L +V+ + L+ E MD ++ +IR + L + + YQL ++ + Sbjct: 70 HPNIISLLDVIRAENDRDIYLVFEFMDTDLNAVIR-KGGLLQDVHVRSIFYQLLRATRFL 128 Query: 120 HRNGIFHRDVKPENILIKQD-VLKLGDFGSCRSVYS------KQPYTEYISTRWYRAPEC 172 H + HRD KP N+L+ + +KL DFG RS+ Q TEY++TRWYRAPE Sbjct: 129 HSGHVVHRDQKPSNVLLDANCTVKLCDFGLARSLGDLPEGPEDQAVTEYVATRWYRAPEV 188 Query: 173 LLTDGFYTYKMDLWSAGCVFYEIASLQPLFPGVNELDQISKIHDVIGTPAQKILTKFK-- 230 LL+ YT +D+WS GC+ E+ +PLFPG + L Q+ I + I P+++ L Sbjct: 189 LLSSHRYTLGVDMWSLGCILGEMLRGRPLFPGTSTLHQLELILETIPPPSEEDLLALGSG 248 Query: 231 -QSRAMNFDFPFKKGSGIPLLTTNLSPQCLSLLHAMVAYDPDERIAAHQALQHPYFQ 286 ++ ++ + + LL + SP+ L LL ++ + PD+R++A QALQHPY Q Sbjct: 249 CRASVLHQLGSRPRQTLDALLPPDTSPEALDLLRRLLVFAPDKRLSATQALQHPYVQ 305 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.320 0.136 0.408 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 17,249,676 Number of Sequences: 37866 Number of extensions: 833393 Number of successful extensions: 4339 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 573 Number of HSP's successfully gapped in prelim test: 220 Number of HSP's that attempted gapping in prelim test: 2431 Number of HSP's gapped (non-prelim): 1050 length of query: 419 length of database: 18,247,518 effective HSP length: 105 effective length of query: 314 effective length of database: 14,271,588 effective search space: 4481278632 effective search space used: 4481278632 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.