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Search of human proteins with 75750480
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|75750480 ras homolog gene family, member T1 isoform 1 [Homo
sapiens]
(691 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|75750480 ras homolog gene family, member T1 isoform 1 [Homo s... 1415 0.0
gi|75750476 ras homolog gene family, member T1 isoform 2 [Homo s... 1332 0.0
gi|75750470 ras homolog gene family, member T1 isoform 3 [Homo s... 1187 0.0
gi|20270303 ras homolog gene family, member T2 [Homo sapiens] 716 0.0
gi|38016957 ras homolog gene family, member F [Homo sapiens] 67 6e-11
gi|7656900 ras homolog D [Homo sapiens] 65 2e-10
gi|4757764 ras homolog gene family, member B [Homo sapiens] 63 8e-10
gi|11034843 ras homolog gene family, member U [Homo sapiens] 61 4e-09
gi|46249393 ras homolog gene family, member G [Homo sapiens] 60 7e-09
gi|16357472 cell division cycle 42 isoform 2 [Homo sapiens] 60 9e-09
gi|89903012 cell division cycle 42 isoform 1 [Homo sapiens] 60 9e-09
gi|4757952 cell division cycle 42 isoform 1 [Homo sapiens] 60 9e-09
gi|50263042 ras-like protein TC10 [Homo sapiens] 59 2e-08
gi|4506381 ras-related C3 botulinum toxin substrate 2 [Homo sapi... 58 3e-08
gi|9845511 ras-related C3 botulinum toxin substrate 1 isoform Ra... 58 3e-08
gi|111494251 ras homolog gene family, member C precursor [Homo s... 58 3e-08
gi|111494248 ras homolog gene family, member C precursor [Homo s... 58 3e-08
gi|28395033 ras homolog gene family, member C precursor [Homo sa... 58 3e-08
gi|10835049 ras homolog gene family, member A [Homo sapiens] 57 4e-08
gi|4757772 DIRAS family, GTP-binding RAS-like 3 [Homo sapiens] 57 7e-08
gi|16903164 ras homolog gene family, member J [Homo sapiens] 57 7e-08
gi|229577148 ras homolog gene family, member V [Homo sapiens] 56 1e-07
gi|20070266 RAS-like GTP-binding protein REM [Homo sapiens] 56 1e-07
gi|4826962 ras-related C3 botulinum toxin substrate 3 (rho famil... 55 3e-07
gi|22027486 RASD family, member 2 [Homo sapiens] 54 5e-07
gi|21703367 Di-Ras2 [Homo sapiens] 53 1e-06
gi|4885069 ras homolog gene family, member E [Homo sapiens] 52 1e-06
gi|38201690 RAP2B, member of RAS oncogene family [Homo sapiens] 52 1e-06
gi|32483371 GTP-binding mitogen-induced T-cell protein [Homo sap... 52 2e-06
gi|7706095 RAS-like, family 12 protein [Homo sapiens] 52 2e-06
>gi|75750480 ras homolog gene family, member T1 isoform 1 [Homo
sapiens]
Length = 691
Score = 1415 bits (3663), Expect = 0.0
Identities = 691/691 (100%), Positives = 691/691 (100%)
Query: 1 MKKDVRILLVGEPRVGKTSLIMSLVSEEFPEEVPPRAEEITIPADVTPERVPTHIVDYSE 60
MKKDVRILLVGEPRVGKTSLIMSLVSEEFPEEVPPRAEEITIPADVTPERVPTHIVDYSE
Sbjct: 1 MKKDVRILLVGEPRVGKTSLIMSLVSEEFPEEVPPRAEEITIPADVTPERVPTHIVDYSE 60
Query: 61 AEQSDEQLHQEISQANVICIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILVGNKS 120
AEQSDEQLHQEISQANVICIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILVGNKS
Sbjct: 61 AEQSDEQLHQEISQANVICIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILVGNKS 120
Query: 121 DLVEYSSMETILPIMNQYTEIETCVECSAKNLKNISELFYYAQKAVLHPTGPLYCPEEKE 180
DLVEYSSMETILPIMNQYTEIETCVECSAKNLKNISELFYYAQKAVLHPTGPLYCPEEKE
Sbjct: 121 DLVEYSSMETILPIMNQYTEIETCVECSAKNLKNISELFYYAQKAVLHPTGPLYCPEEKE 180
Query: 181 MKPACIKALTRIFKISDQDNDGTLNDAELNFFQRICFNTPLAPQALEDVKNVVRKHISDG 240
MKPACIKALTRIFKISDQDNDGTLNDAELNFFQRICFNTPLAPQALEDVKNVVRKHISDG
Sbjct: 181 MKPACIKALTRIFKISDQDNDGTLNDAELNFFQRICFNTPLAPQALEDVKNVVRKHISDG 240
Query: 241 VADSGLTLKGFLFLHTLFIQRGRHETTWTVLRRFGYDDDLDLTPEYLFPLLKIPPDCTTE 300
VADSGLTLKGFLFLHTLFIQRGRHETTWTVLRRFGYDDDLDLTPEYLFPLLKIPPDCTTE
Sbjct: 241 VADSGLTLKGFLFLHTLFIQRGRHETTWTVLRRFGYDDDLDLTPEYLFPLLKIPPDCTTE 300
Query: 301 LNHHAYLFLQSTFDKHDLDRDCALSPDELKDLFKVFPYIPWGPDVNNTVCTNERGWITYQ 360
LNHHAYLFLQSTFDKHDLDRDCALSPDELKDLFKVFPYIPWGPDVNNTVCTNERGWITYQ
Sbjct: 301 LNHHAYLFLQSTFDKHDLDRDCALSPDELKDLFKVFPYIPWGPDVNNTVCTNERGWITYQ 360
Query: 361 GFLSQWTLTTYLDVQRCLEYLGYLGYSILTEQESQASAVTVTRDKKIDLQKKQTQRNVFR 420
GFLSQWTLTTYLDVQRCLEYLGYLGYSILTEQESQASAVTVTRDKKIDLQKKQTQRNVFR
Sbjct: 361 GFLSQWTLTTYLDVQRCLEYLGYLGYSILTEQESQASAVTVTRDKKIDLQKKQTQRNVFR 420
Query: 421 CNVIGVKNCGKSGVLQALLGRNLMRQKKIREDHKSYYAINTVYVYGQEKYLLLHDISESE 480
CNVIGVKNCGKSGVLQALLGRNLMRQKKIREDHKSYYAINTVYVYGQEKYLLLHDISESE
Sbjct: 421 CNVIGVKNCGKSGVLQALLGRNLMRQKKIREDHKSYYAINTVYVYGQEKYLLLHDISESE 480
Query: 481 FLTEAEIICDVVCLVYDVSNPKSFEYCARIFKQHFMDSRIPCLIVAAKSDLHEVKQEYSI 540
FLTEAEIICDVVCLVYDVSNPKSFEYCARIFKQHFMDSRIPCLIVAAKSDLHEVKQEYSI
Sbjct: 481 FLTEAEIICDVVCLVYDVSNPKSFEYCARIFKQHFMDSRIPCLIVAAKSDLHEVKQEYSI 540
Query: 541 SPTDFCRKHKMPPPQAFTCNTADAPSKDIFVKLTTMAMYPEDHYRDRLSRDMGHTDRIEN 600
SPTDFCRKHKMPPPQAFTCNTADAPSKDIFVKLTTMAMYPEDHYRDRLSRDMGHTDRIEN
Sbjct: 541 SPTDFCRKHKMPPPQAFTCNTADAPSKDIFVKLTTMAMYPEDHYRDRLSRDMGHTDRIEN 600
Query: 601 LRKIWVFLKTAFHARLRCMCTCNRCTFCICQNFLNSDLLQSVKNKIFTAVLNRHVTQADL 660
LRKIWVFLKTAFHARLRCMCTCNRCTFCICQNFLNSDLLQSVKNKIFTAVLNRHVTQADL
Sbjct: 601 LRKIWVFLKTAFHARLRCMCTCNRCTFCICQNFLNSDLLQSVKNKIFTAVLNRHVTQADL 660
Query: 661 KSSTFWLRASFGATVFAVLGFAMYKALLKQR 691
KSSTFWLRASFGATVFAVLGFAMYKALLKQR
Sbjct: 661 KSSTFWLRASFGATVFAVLGFAMYKALLKQR 691
>gi|75750476 ras homolog gene family, member T1 isoform 2 [Homo
sapiens]
Length = 659
Score = 1332 bits (3446), Expect = 0.0
Identities = 659/691 (95%), Positives = 659/691 (95%), Gaps = 32/691 (4%)
Query: 1 MKKDVRILLVGEPRVGKTSLIMSLVSEEFPEEVPPRAEEITIPADVTPERVPTHIVDYSE 60
MKKDVRILLVGEPRVGKTSLIMSLVSEEFPEEVPPRAEEITIPADVTPERVPTHIVDYSE
Sbjct: 1 MKKDVRILLVGEPRVGKTSLIMSLVSEEFPEEVPPRAEEITIPADVTPERVPTHIVDYSE 60
Query: 61 AEQSDEQLHQEISQANVICIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILVGNKS 120
AEQSDEQLHQEISQANVICIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILVGNKS
Sbjct: 61 AEQSDEQLHQEISQANVICIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILVGNKS 120
Query: 121 DLVEYSSMETILPIMNQYTEIETCVECSAKNLKNISELFYYAQKAVLHPTGPLYCPEEKE 180
DLVEYSSMETILPIMNQYTEIETCVECSAKNLKNISELFYYAQKAVLHPTGPLYCPEEKE
Sbjct: 121 DLVEYSSMETILPIMNQYTEIETCVECSAKNLKNISELFYYAQKAVLHPTGPLYCPEEKE 180
Query: 181 MKPACIKALTRIFKISDQDNDGTLNDAELNFFQRICFNTPLAPQALEDVKNVVRKHISDG 240
MKPACIKALTRIFKISDQDNDGTLNDAELNFFQRICFNTPLAPQALEDVKNVVRKHISDG
Sbjct: 181 MKPACIKALTRIFKISDQDNDGTLNDAELNFFQRICFNTPLAPQALEDVKNVVRKHISDG 240
Query: 241 VADSGLTLKGFLFLHTLFIQRGRHETTWTVLRRFGYDDDLDLTPEYLFPLLKIPPDCTTE 300
VADSGLTLKGFLFLHTLFIQRGRHETTWTVLRRFGYDDDLDLTPEYLFPLLKIPPDCTTE
Sbjct: 241 VADSGLTLKGFLFLHTLFIQRGRHETTWTVLRRFGYDDDLDLTPEYLFPLLKIPPDCTTE 300
Query: 301 LNHHAYLFLQSTFDKHDLDRDCALSPDELKDLFKVFPYIPWGPDVNNTVCTNERGWITYQ 360
LNHHAYLFLQSTFDKHDLDRDCALSPDELKDLFKVFPYIPWGPDVNNTVCTNERGWITYQ
Sbjct: 301 LNHHAYLFLQSTFDKHDLDRDCALSPDELKDLFKVFPYIPWGPDVNNTVCTNERGWITYQ 360
Query: 361 GFLSQWTLTTYLDVQRCLEYLGYLGYSILTEQESQASAVTVTRDKKIDLQKKQTQRNVFR 420
GFLSQWTLTTYLDVQRCLEYLGYLGYSILTEQESQASAVTVTRDKKIDLQKKQTQRNVFR
Sbjct: 361 GFLSQWTLTTYLDVQRCLEYLGYLGYSILTEQESQASAVTVTRDKKIDLQKKQTQRNVFR 420
Query: 421 CNVIGVKNCGKSGVLQALLGRNLMRQKKIREDHKSYYAINTVYVYGQEKYLLLHDISESE 480
CNVIGVKNCGKSGVLQALLGRNLMRQKKIREDHKSYYAINTVYVYGQEKYLLLHDISESE
Sbjct: 421 CNVIGVKNCGKSGVLQALLGRNLMRQKKIREDHKSYYAINTVYVYGQEKYLLLHDISESE 480
Query: 481 FLTEAEIICDVVCLVYDVSNPKSFEYCARIFKQHFMDSRIPCLIVAAKSDLHEVKQEYSI 540
FLTEAEIICDVVCLVYDVSNPKSFEYCARIFKQHFMDSRIPCLIVAAKSDLHEVKQEYSI
Sbjct: 481 FLTEAEIICDVVCLVYDVSNPKSFEYCARIFKQHFMDSRIPCLIVAAKSDLHEVKQEYSI 540
Query: 541 SPTDFCRKHKMPPPQAFTCNTADAPSKDIFVKLTTMAMYPEDHYRDRLSRDMGHTDRIEN 600
SPTDFCRKHKMPPPQAFTCNTADAPSKDIFVKLTTMAMYP
Sbjct: 541 SPTDFCRKHKMPPPQAFTCNTADAPSKDIFVKLTTMAMYP-------------------- 580
Query: 601 LRKIWVFLKTAFHARLRCMCTCNRCTFCICQNFLNSDLLQSVKNKIFTAVLNRHVTQADL 660
HARLRCMCTCNRCTFCICQNFLNSDLLQSVKNKIFTAVLNRHVTQADL
Sbjct: 581 ------------HARLRCMCTCNRCTFCICQNFLNSDLLQSVKNKIFTAVLNRHVTQADL 628
Query: 661 KSSTFWLRASFGATVFAVLGFAMYKALLKQR 691
KSSTFWLRASFGATVFAVLGFAMYKALLKQR
Sbjct: 629 KSSTFWLRASFGATVFAVLGFAMYKALLKQR 659
>gi|75750470 ras homolog gene family, member T1 isoform 3 [Homo
sapiens]
Length = 618
Score = 1187 bits (3070), Expect = 0.0
Identities = 580/580 (100%), Positives = 580/580 (100%)
Query: 1 MKKDVRILLVGEPRVGKTSLIMSLVSEEFPEEVPPRAEEITIPADVTPERVPTHIVDYSE 60
MKKDVRILLVGEPRVGKTSLIMSLVSEEFPEEVPPRAEEITIPADVTPERVPTHIVDYSE
Sbjct: 1 MKKDVRILLVGEPRVGKTSLIMSLVSEEFPEEVPPRAEEITIPADVTPERVPTHIVDYSE 60
Query: 61 AEQSDEQLHQEISQANVICIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILVGNKS 120
AEQSDEQLHQEISQANVICIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILVGNKS
Sbjct: 61 AEQSDEQLHQEISQANVICIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILVGNKS 120
Query: 121 DLVEYSSMETILPIMNQYTEIETCVECSAKNLKNISELFYYAQKAVLHPTGPLYCPEEKE 180
DLVEYSSMETILPIMNQYTEIETCVECSAKNLKNISELFYYAQKAVLHPTGPLYCPEEKE
Sbjct: 121 DLVEYSSMETILPIMNQYTEIETCVECSAKNLKNISELFYYAQKAVLHPTGPLYCPEEKE 180
Query: 181 MKPACIKALTRIFKISDQDNDGTLNDAELNFFQRICFNTPLAPQALEDVKNVVRKHISDG 240
MKPACIKALTRIFKISDQDNDGTLNDAELNFFQRICFNTPLAPQALEDVKNVVRKHISDG
Sbjct: 181 MKPACIKALTRIFKISDQDNDGTLNDAELNFFQRICFNTPLAPQALEDVKNVVRKHISDG 240
Query: 241 VADSGLTLKGFLFLHTLFIQRGRHETTWTVLRRFGYDDDLDLTPEYLFPLLKIPPDCTTE 300
VADSGLTLKGFLFLHTLFIQRGRHETTWTVLRRFGYDDDLDLTPEYLFPLLKIPPDCTTE
Sbjct: 241 VADSGLTLKGFLFLHTLFIQRGRHETTWTVLRRFGYDDDLDLTPEYLFPLLKIPPDCTTE 300
Query: 301 LNHHAYLFLQSTFDKHDLDRDCALSPDELKDLFKVFPYIPWGPDVNNTVCTNERGWITYQ 360
LNHHAYLFLQSTFDKHDLDRDCALSPDELKDLFKVFPYIPWGPDVNNTVCTNERGWITYQ
Sbjct: 301 LNHHAYLFLQSTFDKHDLDRDCALSPDELKDLFKVFPYIPWGPDVNNTVCTNERGWITYQ 360
Query: 361 GFLSQWTLTTYLDVQRCLEYLGYLGYSILTEQESQASAVTVTRDKKIDLQKKQTQRNVFR 420
GFLSQWTLTTYLDVQRCLEYLGYLGYSILTEQESQASAVTVTRDKKIDLQKKQTQRNVFR
Sbjct: 361 GFLSQWTLTTYLDVQRCLEYLGYLGYSILTEQESQASAVTVTRDKKIDLQKKQTQRNVFR 420
Query: 421 CNVIGVKNCGKSGVLQALLGRNLMRQKKIREDHKSYYAINTVYVYGQEKYLLLHDISESE 480
CNVIGVKNCGKSGVLQALLGRNLMRQKKIREDHKSYYAINTVYVYGQEKYLLLHDISESE
Sbjct: 421 CNVIGVKNCGKSGVLQALLGRNLMRQKKIREDHKSYYAINTVYVYGQEKYLLLHDISESE 480
Query: 481 FLTEAEIICDVVCLVYDVSNPKSFEYCARIFKQHFMDSRIPCLIVAAKSDLHEVKQEYSI 540
FLTEAEIICDVVCLVYDVSNPKSFEYCARIFKQHFMDSRIPCLIVAAKSDLHEVKQEYSI
Sbjct: 481 FLTEAEIICDVVCLVYDVSNPKSFEYCARIFKQHFMDSRIPCLIVAAKSDLHEVKQEYSI 540
Query: 541 SPTDFCRKHKMPPPQAFTCNTADAPSKDIFVKLTTMAMYP 580
SPTDFCRKHKMPPPQAFTCNTADAPSKDIFVKLTTMAMYP
Sbjct: 541 SPTDFCRKHKMPPPQAFTCNTADAPSKDIFVKLTTMAMYP 580
Score = 80.9 bits (198), Expect = 4e-15
Identities = 40/47 (85%), Positives = 42/47 (89%)
Query: 645 KIFTAVLNRHVTQADLKSSTFWLRASFGATVFAVLGFAMYKALLKQR 691
K+ T + HVTQADLKSSTFWLRASFGATVFAVLGFAMYKALLKQR
Sbjct: 572 KLTTMAMYPHVTQADLKSSTFWLRASFGATVFAVLGFAMYKALLKQR 618
>gi|20270303 ras homolog gene family, member T2 [Homo sapiens]
Length = 618
Score = 716 bits (1849), Expect = 0.0
Identities = 354/581 (60%), Positives = 442/581 (76%), Gaps = 5/581 (0%)
Query: 1 MKKDVRILLVGEPRVGKTSLIMSLVSEEFPEEVPPRAEEITIPADVTPERVPTHIVDYSE 60
M++DVRILL+GE +VGKTSLI+SLV EEFPEEVPPRAEEITIPADVTPE+VPTHIVDYSE
Sbjct: 1 MRRDVRILLLGEAQVGKTSLILSLVGEEFPEEVPPRAEEITIPADVTPEKVPTHIVDYSE 60
Query: 61 AEQSDEQLHQEISQANVICIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILVGNKS 120
AEQ+DE+L +EI +ANV+C+VY V+ + +I+K+ ++WIPL+N T + R+P+ILVGNKS
Sbjct: 61 AEQTDEELREEIHKANVVCVVYDVSEEATIEKIRTKWIPLVNGGTTQGPRVPIILVGNKS 120
Query: 121 DLVEYSSMETILPIMNQYTEIETCVECSAKNLKNISELFYYAQKAVLHPTGPLYCPEEKE 180
DL SSME +LPIM+Q+ EIETCVECSAKNL+NISELFYYAQKAVLHPT PLY PE K+
Sbjct: 121 DLRSGSSMEAVLPIMSQFPEIETCVECSAKNLRNISELFYYAQKAVLHPTAPLYDPEAKQ 180
Query: 181 MKPACIKALTRIFKISDQDNDGTLNDAELNFFQRICFNTPLAPQALEDVKNVVRKHISDG 240
++PAC +ALTRIF++SDQD D L+D ELN FQ+ CF PLAPQALEDVK VV ++++ G
Sbjct: 181 LRPACAQALTRIFRLSDQDLDQALSDEELNAFQKSCFGHPLAPQALEDVKTVVCRNVAGG 240
Query: 241 VADSGLTLKGFLFLHTLFIQRGRHETTWTVLRRFGYDDDLDLTPEYLFPLLKIPPDCTTE 300
V + LTL GFLFL+TLFIQRGRHETTWT+LRRFGY D L+LT +YL PL+ +PP C+TE
Sbjct: 241 VREDRLTLDGFLFLNTLFIQRGRHETTWTILRRFGYSDALELTADYLSPLIHVPPGCSTE 300
Query: 301 LNHHAYLFLQSTFDKHDLDRDCALSPDELKDLFKVFPYIPWGPDVNNTVCTNERGWITYQ 360
LNH Y F+Q F+KHD DRD ALSP EL+ LF VFP PWGP++ TV T E G +
Sbjct: 301 LNHLGYQFVQRVFEKHDQDRDGALSPVELQSLFSVFPAAPWGPELPRTVRT-EAGRLPLH 359
Query: 361 GFLSQWTLTTYLDVQRCLEYLGYLGYSILTEQESQASAVTVTRDKKIDLQKKQTQRNVFR 420
G+L QWTL TYLDV+ CL +LGYLGY L EQ+ QA A+TVTR+K++D +K QTQR+V
Sbjct: 360 GYLCQWTLVTYLDVRSCLGHLGYLGYPTLCEQD-QAHAITVTREKRLDQEKGQTQRSVLL 418
Query: 421 CNVIGVKNCGKSGVLQALLGRNLMRQKKIREDHKSYYAINTVYVYGQEKYLLLHDISESE 480
C V+G + GKS LQA LGR L Q + YAI+TV V GQEKYL+L ++
Sbjct: 419 CKVVGARGVGKSAFLQAFLGRGLGHQD--TREQPPGYAIDTVQVNGQEKYLILCEVGTDG 476
Query: 481 FL-TEAEIICDVVCLVYDVSNPKSFEYCARIFKQHFMDSRIPCLIVAAKSDLHEVKQEYS 539
L T + CDV CL++D S+PKSF +CA ++K H+MD + PCL V++K+DL E
Sbjct: 477 LLATSLDATCDVACLMFDGSDPKSFAHCASVYKHHYMDGQTPCLFVSSKADLPEGVAVSG 536
Query: 540 ISPTDFCRKHKMPPPQAFTCNTADAPSKDIFVKLTTMAMYP 580
SP +FCRKH++P P F+C PS IF +L TMA +P
Sbjct: 537 PSPAEFCRKHRLPAPVPFSCAGPAEPSTTIFTQLATMAAFP 577
Score = 37.4 bits (85), Expect = 0.047
Identities = 18/41 (43%), Positives = 26/41 (63%), Gaps = 3/41 (7%)
Query: 654 HVTQADLKSSTFWLRASF---GATVFAVLGFAMYKALLKQR 691
H+ A+L S+FWLR GA V AVL F++Y+ L+K +
Sbjct: 578 HLVHAELHPSSFWLRGLLGVVGAAVAAVLSFSLYRVLVKSQ 618
>gi|38016957 ras homolog gene family, member F [Homo sapiens]
Length = 211
Score = 67.0 bits (162), Expect = 6e-11
Identities = 50/180 (27%), Positives = 82/180 (45%), Gaps = 17/180 (9%)
Query: 2 KKDVRILLVGEPRVGKTSLIMSLVSEEFPEEVPPRA-EEITIPADVTPERVPTHIVDYSE 60
+K+++I++VG+ GKTSL+M FPE P E+ T V + V ++ D +
Sbjct: 17 RKELKIVIVGDGGCGKTSLLMVYSQGSFPEHYAPSVFEKYTASVTVGSKEVTLNLYDTAG 76
Query: 61 AEQSDEQLHQEISQANVICIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILVGNKS 120
E D +++ I Y V N S D V +W P E T +P++L+G K+
Sbjct: 77 QEDYDRLRPLSYQNTHLVLICYDVMNPTSYDNVLIKWFP---EVTHFCRGIPMVLIGCKT 133
Query: 121 DL---------VEYSSMETILPIMN----QYTEIETCVECSAKNLKNISELFYYAQKAVL 167
DL + + +E I + + +ECSAK +N+ ++F A K L
Sbjct: 134 DLRKDKEQLRKLRAAQLEPITYMQGLSACEQIRAALYLECSAKFRENVEDVFREAAKVAL 193
>gi|7656900 ras homolog D [Homo sapiens]
Length = 210
Score = 65.5 bits (158), Expect = 2e-10
Identities = 51/183 (27%), Positives = 83/183 (45%), Gaps = 17/183 (9%)
Query: 3 KDVRILLVGEPRVGKTSLIMSLVSEEFPEEVPPRA-EEITIPADVTPERVPTHIVDYSEA 61
+ V+++LVG+ GKTSL+M FPE P E + V + V HI D +
Sbjct: 16 RSVKVVLVGDGGCGKTSLLMVFADGAFPESYTPTVFERYMVNLQVKGKPVHLHIWDTAGQ 75
Query: 62 EQSDEQLHQEISQANVICIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILVGNKSD 121
+ D A+V+ + + V + +S D + +RW P +N K +P+I+VG K+D
Sbjct: 76 DDYDRLRPLFYPDASVLLLCFDVTSPNSFDNIFNRWYPEVNHFCKK---VPIIVVGCKTD 132
Query: 122 LVEYSSMETIL------PI-------MNQYTEIETCVECSAKNLKNISELFYYAQKAVLH 168
L + S+ L P+ M + +ECSA+ N+ +F A + L
Sbjct: 133 LRKDKSLVNKLRRNGLEPVTYHRGQEMARSVGAVAYLECSARLHDNVHAVFQEAAEVALS 192
Query: 169 PTG 171
G
Sbjct: 193 SRG 195
>gi|4757764 ras homolog gene family, member B [Homo sapiens]
Length = 196
Score = 63.2 bits (152), Expect = 8e-10
Identities = 46/176 (26%), Positives = 80/176 (45%), Gaps = 17/176 (9%)
Query: 6 RILLVGEPRVGKTSLIMSLVSEEFPE-EVPPRAEEITIPADVTPERVPTHIVDYSEAEQS 64
++++VG+ GKT L++ +EFPE VP E +V ++V + D + E
Sbjct: 7 KLVVVGDGACGKTCLLIVFSKDEFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDY 66
Query: 65 DEQLHQEISQANVICIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILVGNKSDLVE 124
D +VI + ++V++ S++ + +W+P + +P+ILV NK DL
Sbjct: 67 DRLRPLSYPDTDVILMCFSVDSPDSLENIPEKWVPEVKHFC---PNVPIILVANKKDLRS 123
Query: 125 YSSMETILPIMNQ-------------YTEIETCVECSAKNLKNISELFYYAQKAVL 167
+ T L M Q + +ECSAK + + E+F A +A L
Sbjct: 124 DEHVRTELARMKQEPVRTDDGRAMAVRIQAYDYLECSAKTKEGVREVFETATRAAL 179
>gi|11034843 ras homolog gene family, member U [Homo sapiens]
Length = 258
Score = 60.8 bits (146), Expect = 4e-09
Identities = 43/171 (25%), Positives = 79/171 (46%), Gaps = 17/171 (9%)
Query: 3 KDVRILLVGEPRVGKTSLIMSLVSEEFPEE-VPPRAEEITIPADVTPERVPTHIVDYSEA 61
+ V+ +LVG+ VGKTSL++S + +P E +P + + V V + D +
Sbjct: 48 RGVKCVLVGDGAVGKTSLVVSYTTNGYPTEYIPTAFDNFSAVVSVDGRPVRLQLCDTAGQ 107
Query: 62 EQSDEQLHQEISQANVICIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILVGNKSD 121
++ D+ + ++ + ++V + S V+ +W+P I K P+ILVG +SD
Sbjct: 108 DEFDKLRPLCYTNTDIFLLCFSVVSPSSFQNVSEKWVPEIRCHCPK---APIILVGTQSD 164
Query: 122 LVEYSSM-------------ETILPIMNQYTEIETCVECSAKNLKNISELF 159
L E + E + + + + +ECSA KN+ E+F
Sbjct: 165 LREDVKVLIELDKCKEKPVPEEAAKLCAEEIKAASYIECSALTQKNLKEVF 215
>gi|46249393 ras homolog gene family, member G [Homo sapiens]
Length = 191
Score = 60.1 bits (144), Expect = 7e-09
Identities = 46/182 (25%), Positives = 81/182 (44%), Gaps = 17/182 (9%)
Query: 3 KDVRILLVGEPRVGKTSLIMSLVSEEFPEE-VPPRAEEITIPADVTPERVPTHIVDYSEA 61
+ ++ ++VG+ VGKT L++ + FP+E +P + + + V V ++ D +
Sbjct: 2 QSIKCVVVGDGAVGKTCLLICYTTNAFPKEYIPTVFDNYSAQSAVDGRTVNLNLWDTAGQ 61
Query: 62 EQSDEQLHQEISQANVICIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILVGNKSD 121
E+ D Q NV I +++ + S + V +W P + +P++LVG K D
Sbjct: 62 EEYDRLRTLSYPQTNVFVICFSIASPPSYENVRHKWHPEVCHHCPD---VPILLVGTKKD 118
Query: 122 L---------VEYSSMETILPIMNQ----YTEIETCVECSAKNLKNISELFYYAQKAVLH 168
L ++ I P Q +ECSA + E+F A +AVL+
Sbjct: 119 LRAQPDTLRRLKEQGQAPITPQQGQALAKQIHAVRYLECSALQQDGVKEVFAEAVRAVLN 178
Query: 169 PT 170
PT
Sbjct: 179 PT 180
>gi|16357472 cell division cycle 42 isoform 2 [Homo sapiens]
Length = 191
Score = 59.7 bits (143), Expect = 9e-09
Identities = 50/196 (25%), Positives = 82/196 (41%), Gaps = 23/196 (11%)
Query: 5 VRILLVGEPRVGKTSLIMSLVSEEFPEE-VPPRAEEITIPADVTPERVPTHIVDYSEAEQ 63
++ ++VG+ VGKT L++S + +FP E VP + + + E + D + E
Sbjct: 4 IKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAGQED 63
Query: 64 SDEQLHQEISQANVICIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILVGNKSDL- 122
D Q +V + ++V + S + V +W+P I K P +LVG + DL
Sbjct: 64 YDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPK---TPFLLVGTQIDLR 120
Query: 123 -----VEYSSMETILPIMNQYTE-------IETCVECSAKNLKNISELFYYAQKAVLHPT 170
+E + PI + E VECSA + + +F A A L P
Sbjct: 121 DDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQRGLKNVFDEAILAALEP- 179
Query: 171 GPLYCPEEKEMKPACI 186
PE + + CI
Sbjct: 180 -----PETQPKRKCCI 190
>gi|89903012 cell division cycle 42 isoform 1 [Homo sapiens]
Length = 191
Score = 59.7 bits (143), Expect = 9e-09
Identities = 48/182 (26%), Positives = 77/182 (42%), Gaps = 17/182 (9%)
Query: 5 VRILLVGEPRVGKTSLIMSLVSEEFPEE-VPPRAEEITIPADVTPERVPTHIVDYSEAEQ 63
++ ++VG+ VGKT L++S + +FP E VP + + + E + D + E
Sbjct: 4 IKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAGQED 63
Query: 64 SDEQLHQEISQANVICIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILVGNKSDL- 122
D Q +V + ++V + S + V +W+P I K P +LVG + DL
Sbjct: 64 YDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPK---TPFLLVGTQIDLR 120
Query: 123 -----VEYSSMETILPIMNQYTE-------IETCVECSAKNLKNISELFYYAQKAVLHPT 170
+E + PI + E VECSA K + +F A A L P
Sbjct: 121 DDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQKGLKNVFDEAILAALEPP 180
Query: 171 GP 172
P
Sbjct: 181 EP 182
>gi|4757952 cell division cycle 42 isoform 1 [Homo sapiens]
Length = 191
Score = 59.7 bits (143), Expect = 9e-09
Identities = 48/182 (26%), Positives = 77/182 (42%), Gaps = 17/182 (9%)
Query: 5 VRILLVGEPRVGKTSLIMSLVSEEFPEE-VPPRAEEITIPADVTPERVPTHIVDYSEAEQ 63
++ ++VG+ VGKT L++S + +FP E VP + + + E + D + E
Sbjct: 4 IKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAGQED 63
Query: 64 SDEQLHQEISQANVICIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILVGNKSDL- 122
D Q +V + ++V + S + V +W+P I K P +LVG + DL
Sbjct: 64 YDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPK---TPFLLVGTQIDLR 120
Query: 123 -----VEYSSMETILPIMNQYTE-------IETCVECSAKNLKNISELFYYAQKAVLHPT 170
+E + PI + E VECSA K + +F A A L P
Sbjct: 121 DDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQKGLKNVFDEAILAALEPP 180
Query: 171 GP 172
P
Sbjct: 181 EP 182
>gi|50263042 ras-like protein TC10 [Homo sapiens]
Length = 205
Score = 58.9 bits (141), Expect = 2e-08
Identities = 49/179 (27%), Positives = 77/179 (43%), Gaps = 17/179 (9%)
Query: 5 VRILLVGEPRVGKTSLIMSLVSEEFPEE-VPPRAEEITIPADVTPERVPTHIVDYSEAEQ 63
++ ++VG+ VGKT L+MS ++ FPEE VP + + V ++ + D + E
Sbjct: 10 LKCVVVGDGAVGKTCLLMSYANDAFPEEYVPTVFDHYAVSVTVGGKQYLLGLYDTAGQED 69
Query: 64 SDEQLHQEISQANVICIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILVGNKSDLV 123
D +V I ++V N S V W+P + E +P +L+G + DL
Sbjct: 70 YDRLRPLSYPMTDVFLICFSVVNPASFQNVKEEWVPELKEYA---PNVPFLLIGTQIDLR 126
Query: 124 EYSSMETILPIMNQ-----------YTEIETC--VECSAKNLKNISELFYYAQKAVLHP 169
+ L M + EI C VECSA K + +F A A+L P
Sbjct: 127 DDPKTLARLNDMKEKPICVEQGQKLAKEIGACCYVECSALTQKGLKTVFDEAIIAILTP 185
>gi|4506381 ras-related C3 botulinum toxin substrate 2 [Homo
sapiens]
Length = 192
Score = 58.2 bits (139), Expect = 3e-08
Identities = 53/197 (26%), Positives = 93/197 (47%), Gaps = 27/197 (13%)
Query: 5 VRILLVGEPRVGKTSLIMSLVSEEFPEEVPPRAEEITIPADVTPERVPTHIVDYSEAEQS 64
++ ++VG+ VGKT L++S + FP E P + A+V + P ++ + A Q
Sbjct: 4 IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFD-NYSANVMVDSKPVNLGLWDTAGQE 62
Query: 65 DEQLHQEIS--QANVICIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILVGNKSDL 122
D + +S Q +V I +++ + S + V ++W P + P+ILVG K DL
Sbjct: 63 DYDRLRPLSYPQTDVFLICFSLVSPASYENVRAKWFPEVRHHCPS---TPIILVGTKLDL 119
Query: 123 ------VEYSSMETILPI-----MNQYTEIETC--VECSAKNLKNISELFYYAQKAVLHP 169
+E + + PI + EI++ +ECSA + + +F A +AVL
Sbjct: 120 RDDKDTIEKLKEKKLAPITYPQGLALAKEIDSVKYLECSALTQRGLKTVFDEAIRAVL-- 177
Query: 170 TGPLYCPE-EKEMKPAC 185
CP+ ++ K AC
Sbjct: 178 -----CPQPTRQQKRAC 189
>gi|9845511 ras-related C3 botulinum toxin substrate 1 isoform Rac1
[Homo sapiens]
Length = 192
Score = 57.8 bits (138), Expect = 3e-08
Identities = 52/197 (26%), Positives = 89/197 (45%), Gaps = 25/197 (12%)
Query: 5 VRILLVGEPRVGKTSLIMSLVSEEFPEEVPPRAEEITIPADVTPERVPTHIVDYSEAEQS 64
++ ++VG+ VGKT L++S + FP E P + A+V + P ++ + A Q
Sbjct: 4 IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFD-NYSANVMVDGKPVNLGLWDTAGQE 62
Query: 65 DEQLHQEIS--QANVICIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILVGNKSDL 122
D + +S Q +V I +++ + S + V ++W P + P+ILVG K DL
Sbjct: 63 DYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHC---PNTPIILVGTKLDL 119
Query: 123 ------VEYSSMETILPI-------MNQYTEIETCVECSAKNLKNISELFYYAQKAVLHP 169
+E + + PI M + +ECSA + + +F A +AVL P
Sbjct: 120 RDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCP 179
Query: 170 TGPLYCPEEKEMKPACI 186
P K+ K C+
Sbjct: 180 ------PPVKKRKRKCL 190
>gi|111494251 ras homolog gene family, member C precursor [Homo
sapiens]
Length = 193
Score = 57.8 bits (138), Expect = 3e-08
Identities = 44/176 (25%), Positives = 78/176 (44%), Gaps = 17/176 (9%)
Query: 6 RILLVGEPRVGKTSLIMSLVSEEFPE-EVPPRAEEITIPADVTPERVPTHIVDYSEAEQS 64
++++VG+ GKT L++ ++FPE VP E +V ++V + D + E
Sbjct: 7 KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDGKQVELALWDTAGQEDY 66
Query: 65 DEQLHQEISQANVICIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILVGNKSDLVE 124
D +VI + +++++ S++ + +W P + +P+ILVGNK DL +
Sbjct: 67 DRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFC---PNVPIILVGNKKDLRQ 123
Query: 125 YSSMETILPIMNQ-------------YTEIETCVECSAKNLKNISELFYYAQKAVL 167
L M Q +ECSAK + + E+F A +A L
Sbjct: 124 DEHTRRELAKMKQEPVRSEEGRDMANRISAFGYLECSAKTKEGVREVFEMATRAGL 179
>gi|111494248 ras homolog gene family, member C precursor [Homo
sapiens]
Length = 193
Score = 57.8 bits (138), Expect = 3e-08
Identities = 44/176 (25%), Positives = 78/176 (44%), Gaps = 17/176 (9%)
Query: 6 RILLVGEPRVGKTSLIMSLVSEEFPE-EVPPRAEEITIPADVTPERVPTHIVDYSEAEQS 64
++++VG+ GKT L++ ++FPE VP E +V ++V + D + E
Sbjct: 7 KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDGKQVELALWDTAGQEDY 66
Query: 65 DEQLHQEISQANVICIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILVGNKSDLVE 124
D +VI + +++++ S++ + +W P + +P+ILVGNK DL +
Sbjct: 67 DRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFC---PNVPIILVGNKKDLRQ 123
Query: 125 YSSMETILPIMNQ-------------YTEIETCVECSAKNLKNISELFYYAQKAVL 167
L M Q +ECSAK + + E+F A +A L
Sbjct: 124 DEHTRRELAKMKQEPVRSEEGRDMANRISAFGYLECSAKTKEGVREVFEMATRAGL 179
>gi|28395033 ras homolog gene family, member C precursor [Homo
sapiens]
Length = 193
Score = 57.8 bits (138), Expect = 3e-08
Identities = 44/176 (25%), Positives = 78/176 (44%), Gaps = 17/176 (9%)
Query: 6 RILLVGEPRVGKTSLIMSLVSEEFPE-EVPPRAEEITIPADVTPERVPTHIVDYSEAEQS 64
++++VG+ GKT L++ ++FPE VP E +V ++V + D + E
Sbjct: 7 KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDGKQVELALWDTAGQEDY 66
Query: 65 DEQLHQEISQANVICIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILVGNKSDLVE 124
D +VI + +++++ S++ + +W P + +P+ILVGNK DL +
Sbjct: 67 DRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFC---PNVPIILVGNKKDLRQ 123
Query: 125 YSSMETILPIMNQ-------------YTEIETCVECSAKNLKNISELFYYAQKAVL 167
L M Q +ECSAK + + E+F A +A L
Sbjct: 124 DEHTRRELAKMKQEPVRSEEGRDMANRISAFGYLECSAKTKEGVREVFEMATRAGL 179
>gi|10835049 ras homolog gene family, member A [Homo sapiens]
Length = 193
Score = 57.4 bits (137), Expect = 4e-08
Identities = 44/176 (25%), Positives = 76/176 (43%), Gaps = 17/176 (9%)
Query: 6 RILLVGEPRVGKTSLIMSLVSEEFPE-EVPPRAEEITIPADVTPERVPTHIVDYSEAEQS 64
++++VG+ GKT L++ ++FPE VP E +V ++V + D + E
Sbjct: 7 KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDY 66
Query: 65 DEQLHQEISQANVICIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILVGNKSDLVE 124
D +VI + +++++ S++ + +W P + +P+ILVGNK DL
Sbjct: 67 DRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFC---PNVPIILVGNKKDLRN 123
Query: 125 YSSMETILPIMNQYTEIET-------------CVECSAKNLKNISELFYYAQKAVL 167
L M Q +ECSAK + E+F A +A L
Sbjct: 124 DEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAAL 179
>gi|4757772 DIRAS family, GTP-binding RAS-like 3 [Homo sapiens]
Length = 229
Score = 56.6 bits (135), Expect = 7e-08
Identities = 49/190 (25%), Positives = 83/190 (43%), Gaps = 18/190 (9%)
Query: 3 KDVRILLVGEPRVGKTSLIMSLVSEEFPEEVPPRAEEITIPADVTPERVPT-HIVDYSEA 61
+D R+++VG VGK++L+ S F E P E V + HI D
Sbjct: 36 RDYRVVVVGTAGVGKSTLLHKWASGNFRHEYLPTIENTYCQLLGCSHGVLSLHITDSKSG 95
Query: 62 EQSDEQLHQEISQANVICIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILVGNKSD 121
+ + I++ + +VY+V K +++++ + + + + + + P++LVGNKSD
Sbjct: 96 DGNRALQRHVIARGHAFVLVYSVTKKETLEELKAFYELICKIKGNNLHKFPIVLVGNKSD 155
Query: 122 LVEYSSMETILPIMNQYTEIETC--------VECSAKNLKNISELFYYAQKAVLHPTGPL 173
+ E L + TC +E SAK N+ ELF+ PT L
Sbjct: 156 ---DTHREVAL------NDGATCAMEWNCAFMEISAKTDVNVQELFHMLLNYKKKPTTGL 206
Query: 174 YCPEEKEMKP 183
PE+K P
Sbjct: 207 QEPEKKSQMP 216
>gi|16903164 ras homolog gene family, member J [Homo sapiens]
Length = 214
Score = 56.6 bits (135), Expect = 7e-08
Identities = 51/185 (27%), Positives = 81/185 (43%), Gaps = 23/185 (12%)
Query: 2 KKDVRILLVGEPRVGKTSLIMSLVSEEFPEE-VPPRAEEITIPADVTPERVPTHIVD-YS 59
KK ++ ++VG+ VGKT L+MS ++ FPEE VP + + V ++ H++ Y
Sbjct: 19 KKMLKCVVVGDGAVGKTCLLMSYANDAFPEEYVPTVFDHYAVTVTVGGKQ---HLLGLYD 75
Query: 60 EAEQSDEQLHQEISQAN--VICIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILVG 117
A Q D + +S N V I ++V N S V W+P E D +P +L+G
Sbjct: 76 TAGQEDYNQLRPLSYPNTDVFLICFSVVNPASYHNVQEEWVP---ELKDCMPHVPYVLIG 132
Query: 118 NKSDLVEYSSMETILPIMNQ-------------YTEIETCVECSAKNLKNISELFYYAQK 164
+ DL + L M + + +ECSA K + +F A
Sbjct: 133 TQIDLRDDPKTLARLLYMKEKPLTYEHGVKLAKAIGAQCYLECSALTQKGLKAVFDEAIL 192
Query: 165 AVLHP 169
+ HP
Sbjct: 193 TIFHP 197
>gi|229577148 ras homolog gene family, member V [Homo sapiens]
Length = 236
Score = 56.2 bits (134), Expect = 1e-07
Identities = 51/203 (25%), Positives = 89/203 (43%), Gaps = 24/203 (11%)
Query: 5 VRILLVGEPRVGKTSLIMSLVSEEFPEEVPPRAEEITIPADVTPERVPTHIVDYSEAEQS 64
++ +LVG+ VGK+SLI+S +P P A + T V + P I + A Q
Sbjct: 32 IKCVLVGDGAVGKSSLIVSYTCNGYPARYRPTALD-TFSVQVLVDGAPVRIELWDTAGQE 90
Query: 65 DEQLHQEI--SQANVICIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILVGNKSDL 122
D + + +V ++V S +T +W+P I + + P++LVG ++DL
Sbjct: 91 DFDRLRSLCYPDTDVFLACFSVVQPSSFQNITEKWLPEIRTH---NPQAPVLLVGTQADL 147
Query: 123 ---------VEYSSMETILP---IMNQYTEIETC--VECSAKNLKNISELFYYAQKAVLH 168
++ E +P +I C +ECSA KN+ E+F A + +
Sbjct: 148 RDDVNVLIQLDQGGREGPVPQPQAQGLAEKIRACCYLECSALTQKNLKEVFDSAILSAIE 207
Query: 169 PTGPLYCPEEKEMKPACIKALTR 191
L EK++ ++ L+R
Sbjct: 208 HKARL----EKKLNAKGVRTLSR 226
>gi|20070266 RAS-like GTP-binding protein REM [Homo sapiens]
Length = 298
Score = 56.2 bits (134), Expect = 1e-07
Identities = 49/161 (30%), Positives = 78/161 (48%), Gaps = 13/161 (8%)
Query: 6 RILLVGEPRVGKTSLIMSLVSEE---FPEEVPPRAEEITIPADVTPERVPTHIVDYSEAE 62
R++L+G+P VGKTSL ++ E++ E T+ D E +VD EAE
Sbjct: 82 RVVLLGDPGVGKTSLASLFAGKQERDLHEQLGEDVYERTLTVD--GEDTTLVVVDTWEAE 139
Query: 63 QSDEQLHQE--ISQANVICIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILVGNKS 120
+ D+ QE + + IVY++ ++ S + + I L RT + +P+ILVGNK+
Sbjct: 140 KLDKSWSQESCLQGGSAYVIVYSIADRGSFESASELRIQL--RRTHQADHVPIILVGNKA 197
Query: 121 DLVEYSSMETILPIMNQYTEIETC--VECSAKNLKNISELF 159
DL E + + C +E SA N++ELF
Sbjct: 198 DLAR--CREVSVEEGRACAVVFDCKFIETSATLQHNVAELF 236
>gi|4826962 ras-related C3 botulinum toxin substrate 3 (rho family,
small GTP binding protein Rac3) [Homo sapiens]
Length = 192
Score = 54.7 bits (130), Expect = 3e-07
Identities = 51/190 (26%), Positives = 90/190 (47%), Gaps = 20/190 (10%)
Query: 5 VRILLVGEPRVGKTSLIMSLVSEEFPEEVPPRAEEITIPADVTPERVPTHIVDYSEAEQS 64
++ ++VG+ VGKT L++S + FP E P + A+V + P ++ + A Q
Sbjct: 4 IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFD-NYSANVMVDGKPVNLGLWDTAGQE 62
Query: 65 DEQLHQEIS--QANVICIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILVGNKSDL 122
D + +S Q +V I +++ + S + V ++W P + P++LVG K DL
Sbjct: 63 DYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHC---PHTPILLVGTKLDL 119
Query: 123 ------VEYSSMETILPI-----MNQYTEIETC--VECSAKNLKNISELFYYAQKAVLHP 169
+E + + PI + EI + +ECSA + + +F A +AVL P
Sbjct: 120 RDDKDTIERLRDKKLAPITYPQGLAMAREIGSVKYLECSALTQRGLKTVFDEAIRAVLCP 179
Query: 170 TGPLYCPEEK 179
P+ P +K
Sbjct: 180 P-PVKKPGKK 188
>gi|22027486 RASD family, member 2 [Homo sapiens]
Length = 266
Score = 53.9 bits (128), Expect = 5e-07
Identities = 39/168 (23%), Positives = 75/168 (44%), Gaps = 9/168 (5%)
Query: 2 KKDVRILLVGEPRVGKTSLIMSLVSEEFPEEVPPRAEEITIPA-DVTPERVPTHIVDYSE 60
K R++++G RVGK+S++ ++ F ++ P E+ ++ + I+D S
Sbjct: 17 KNSYRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKVYNIRGDMYQLDILDTSG 76
Query: 61 AEQSDEQLHQEISQANVICIVYAVNNKHSIDKVTSRWIPLIN------ERTDKDSRLPLI 114
I +V +V++++N+ S D+V ++ +T + + LP++
Sbjct: 77 NHPFPAMRRLSILTGDVFILVFSLDNRESFDEVKRLQKQILEVKSCLKNKTKEAAELPMV 136
Query: 115 LVGNKSDLVEYSSMETILPIMNQYTEIETCV--ECSAKNLKNISELFY 160
+ GNK+D E + E C E SAK N+ E+FY
Sbjct: 137 ICGNKNDHGELCRQVPTTEAELLVSGDENCAYFEVSAKKNTNVDEMFY 184
Score = 29.6 bits (65), Expect = 9.8
Identities = 35/137 (25%), Positives = 54/137 (39%), Gaps = 21/137 (15%)
Query: 416 RNVFRCNVIGVKNCGKSGVLQALLGRNLMRQ--KKIREDHKSYYAINTVYVYGQEKYLLL 473
+N +R V+G GKS ++ L Q I + H+ Y I G L +
Sbjct: 17 KNSYRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKVYNIR-----GDMYQLDI 71
Query: 474 HDISESE---FLTEAEIIC-DVVCLVYDVSNPKSFEYCARIFKQHFMDSRIPCLIVAAKS 529
D S + + I+ DV LV+ + N +SF+ R+ KQ I+ KS
Sbjct: 72 LDTSGNHPFPAMRRLSILTGDVFILVFSLDNRESFDEVKRLQKQ----------ILEVKS 121
Query: 530 DLHEVKQEYSISPTDFC 546
L +E + P C
Sbjct: 122 CLKNKTKEAAELPMVIC 138
>gi|21703367 Di-Ras2 [Homo sapiens]
Length = 199
Score = 52.8 bits (125), Expect = 1e-06
Identities = 43/159 (27%), Positives = 73/159 (45%), Gaps = 6/159 (3%)
Query: 4 DVRILLVGEPRVGKTSLIMSLVSEEFPEEVPPRAEEITIPADVTPERVPT-HIVDYSEAE 62
D R+ + G VGK+SL++ V F E P E+ + + T I D + +
Sbjct: 7 DYRVAVFGAGGVGKSSLVLRFVKGTFRESYIPTVEDTYRQVISCDKSICTLQITDTTGSH 66
Query: 63 QSDEQLHQEISQANVICIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILVGNKSDL 122
Q IS+ + +VY++ ++ S++++ + + + D +S +P++LVGNK D
Sbjct: 67 QFPAMQRLSISKGHAFILVYSITSRQSLEELKPIYEQICEIKGDVES-IPIMLVGNKCD- 124
Query: 123 VEYSSMETILPIMNQYTEIETC--VECSAKNLKNISELF 159
E S E C +E SAK N+ ELF
Sbjct: 125 -ESPSREVQSSEAEALARTWKCAFMETSAKLNHNVKELF 162
>gi|4885069 ras homolog gene family, member E [Homo sapiens]
Length = 244
Score = 52.4 bits (124), Expect = 1e-06
Identities = 44/182 (24%), Positives = 84/182 (46%), Gaps = 22/182 (12%)
Query: 6 RILLVGEPRVGKTSLIMSLVSEEFPEE-VPPRAEEITIPADVTPERVPTHIVDYSEAEQS 64
+I++VG+ + GKT+L+ + FPE VP E T ++ +R+ + D S +
Sbjct: 25 KIVVVGDSQCGKTALLHVFAKDCFPENYVPTVFENYTASFEIDTQRIELSLWDTSGSPYY 84
Query: 65 DEQLHQEISQANVICIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILVGNKSDLVE 124
D ++ + I + ++ ++D V +W I E ++LVG KSDL
Sbjct: 85 DNVRPLSYPDSDAVLICFDISRPETLDSVLKKWKGEIQEFCPNTK---MLLVGCKSDL-- 139
Query: 125 YSSMETILPIMN-QYTEIE--------------TCVECSAKNLKN-ISELFYYAQKAVLH 168
+ + T++ + N + T + T +ECSA +N + ++F+ A A ++
Sbjct: 140 RTDVSTLVELSNHRQTPVSYDQGANMAKQIGAATYIECSALQSENSVRDIFHVATLACVN 199
Query: 169 PT 170
T
Sbjct: 200 KT 201
>gi|38201690 RAP2B, member of RAS oncogene family [Homo sapiens]
Length = 183
Score = 52.4 bits (124), Expect = 1e-06
Identities = 46/167 (27%), Positives = 78/167 (46%), Gaps = 21/167 (12%)
Query: 3 KDVRILLVGEPRVGKTSLIMSLVSEEFPEEVPPRAEEI---TIPADVTPERVPTHIVDYS 59
++ +++++G VGK++L + V+ F E+ P E+ I D +P + I+D +
Sbjct: 2 REYKVVVLGSGGVGKSALTVQFVTGSFIEKYDPTIEDFYRKEIEVDSSPSVL--EILDTA 59
Query: 60 EAEQSDEQLHQEISQANVICIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILVGNK 119
EQ I +VY++ N+ S + +I R + R+P+ILVGNK
Sbjct: 60 GTEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQII--RVKRYERVPMILVGNK 117
Query: 120 SDL-----VEYSSMETILPIMNQYTEIETC--VECSAKNLKNISELF 159
DL V Y + + E +C +E SAKN ++ ELF
Sbjct: 118 VDLEGEREVSYGEGKAL-------AEEWSCPFMETSAKNKASVDELF 157
>gi|32483371 GTP-binding mitogen-induced T-cell protein [Homo
sapiens]
Length = 296
Score = 52.0 bits (123), Expect = 2e-06
Identities = 50/162 (30%), Positives = 77/162 (47%), Gaps = 14/162 (8%)
Query: 6 RILLVGEPRVGKTSL--IMSLVSEEFPEEVPPRAE---EITIPADVTPERVPTHIVDYSE 60
R++L+GE VGK++L I + V + + E E T+ D E ++D E
Sbjct: 77 RVVLIGEQGVGKSTLANIFAGVHDSMDSDCEVLGEDTYERTLMVD--GESATIILLDMWE 134
Query: 61 AEQSDEQLHQEISQA-NVICIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILVGNK 119
+ +E LH Q + IVY++ ++ S +K + I L R +D +P+ILVGNK
Sbjct: 135 NKGENEWLHDHCMQVGDAYLIVYSITDRASFEKASELRIQLRRARQTED--IPIILVGNK 192
Query: 120 SDLVEYSSMETILPIMNQYTEIETC--VECSAKNLKNISELF 159
SDLV E + + C +E SA N+ ELF
Sbjct: 193 SDLVR--CREVSVSEGRACAVVFDCKFIETSAAVQHNVKELF 232
>gi|7706095 RAS-like, family 12 protein [Homo sapiens]
Length = 266
Score = 52.0 bits (123), Expect = 2e-06
Identities = 38/191 (19%), Positives = 86/191 (45%), Gaps = 19/191 (9%)
Query: 4 DVRILLVGEPRVGKTSLIMSLVSEEFPEEVPPRAEEITIPADVTPERVPTHIVDYSEAE- 62
+V + ++G GK++L + +++ F E P E+ T ++ T + P H+ A+
Sbjct: 20 EVNLAILGRRGAGKSALTVKFLTKRFISEYDPNLED-TYSSEETVDHQPVHLRVMDTADL 78
Query: 63 QSDEQLHQEISQANVICIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILVGNKSDL 122
+ + ++ A+ +VY+V+++ S D +S L + +P +L+GNK D+
Sbjct: 79 DTPRNCERYLNWAHAFLVVYSVDSRQSFDSSSSYLELLALHAKETQRSIPALLLGNKLDM 138
Query: 123 VEYSSMETILPIMNQ------YTEIETCVECSAKNLKNISELFYYAQKAVLHP------T 170
+Y + + + E+ C++ +++ +F+ A + T
Sbjct: 139 AQYRQVTKAEGVALAGRFGCLFFEVSACLD-----FEHVQHVFHEAVREARRELEKSPLT 193
Query: 171 GPLYCPEEKEM 181
PL+ EE+ +
Sbjct: 194 RPLFISEERAL 204
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.137 0.417
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,132,528
Number of Sequences: 37866
Number of extensions: 1169716
Number of successful extensions: 3269
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 26
Number of HSP's successfully gapped in prelim test: 147
Number of HSP's that attempted gapping in prelim test: 3088
Number of HSP's gapped (non-prelim): 222
length of query: 691
length of database: 18,247,518
effective HSP length: 109
effective length of query: 582
effective length of database: 14,120,124
effective search space: 8217912168
effective search space used: 8217912168
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.