Search of human proteins with 75750470

Search of human proteins with 75750470

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|75750470 ras homolog gene family, member T1 isoform 3 [Homo
sapiens]
         (618 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|75750470 ras homolog gene family, member T1 isoform 3 [Homo s...  1260   0.0  
gi|75750476 ras homolog gene family, member T1 isoform 2 [Homo s...  1240   0.0  
gi|75750480 ras homolog gene family, member T1 isoform 1 [Homo s...  1187   0.0  
gi|20270303 ras homolog gene family, member T2 [Homo sapiens]         749   0.0  
gi|38016957 ras homolog gene family, member F [Homo sapiens]           67   5e-11
gi|7656900 ras homolog D [Homo sapiens]                                65   1e-10
gi|4757764 ras homolog gene family, member B [Homo sapiens]            63   7e-10
gi|11034843 ras homolog gene family, member U [Homo sapiens]           61   3e-09
gi|46249393 ras homolog gene family, member G [Homo sapiens]           60   6e-09
gi|16357472 cell division cycle 42 isoform 2 [Homo sapiens]            60   8e-09
gi|89903012 cell division cycle 42 isoform 1 [Homo sapiens]            60   8e-09
gi|4757952 cell division cycle 42 isoform 1 [Homo sapiens]             60   8e-09
gi|50263042 ras-like protein TC10 [Homo sapiens]                       59   1e-08
gi|4506381 ras-related C3 botulinum toxin substrate 2 [Homo sapi...    58   2e-08
gi|9845511 ras-related C3 botulinum toxin substrate 1 isoform Ra...    58   3e-08
gi|111494251 ras homolog gene family, member C precursor [Homo s...    58   3e-08
gi|111494248 ras homolog gene family, member C precursor [Homo s...    58   3e-08
gi|28395033 ras homolog gene family, member C precursor [Homo sa...    58   3e-08
gi|10835049 ras homolog gene family, member A [Homo sapiens]           57   4e-08
gi|4757772 DIRAS family, GTP-binding RAS-like 3 [Homo sapiens]         57   7e-08
gi|16903164 ras homolog gene family, member J [Homo sapiens]           57   7e-08
gi|229577148 ras homolog gene family, member V [Homo sapiens]          56   9e-08
gi|20070266 RAS-like GTP-binding protein REM [Homo sapiens]            56   9e-08
gi|4826962 ras-related C3 botulinum toxin substrate 3 (rho famil...    55   2e-07
gi|22027486 RASD family, member 2 [Homo sapiens]                       54   4e-07
gi|21703367 Di-Ras2 [Homo sapiens]                                     53   9e-07
gi|4885069 ras homolog gene family, member E [Homo sapiens]            52   1e-06
gi|38201690 RAP2B, member of RAS oncogene family [Homo sapiens]        52   1e-06
gi|32483371 GTP-binding mitogen-induced T-cell protein [Homo sap...    52   2e-06
gi|7706095 RAS-like, family 12 protein [Homo sapiens]                  52   2e-06

>gi|75750470 ras homolog gene family, member T1 isoform 3 [Homo
           sapiens]
          Length = 618

 Score = 1260 bits (3261), Expect = 0.0
 Identities = 618/618 (100%), Positives = 618/618 (100%)

Query: 1   MKKDVRILLVGEPRVGKTSLIMSLVSEEFPEEVPPRAEEITIPADVTPERVPTHIVDYSE 60
           MKKDVRILLVGEPRVGKTSLIMSLVSEEFPEEVPPRAEEITIPADVTPERVPTHIVDYSE
Sbjct: 1   MKKDVRILLVGEPRVGKTSLIMSLVSEEFPEEVPPRAEEITIPADVTPERVPTHIVDYSE 60

Query: 61  AEQSDEQLHQEISQANVICIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILVGNKS 120
           AEQSDEQLHQEISQANVICIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILVGNKS
Sbjct: 61  AEQSDEQLHQEISQANVICIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILVGNKS 120

Query: 121 DLVEYSSMETILPIMNQYTEIETCVECSAKNLKNISELFYYAQKAVLHPTGPLYCPEEKE 180
           DLVEYSSMETILPIMNQYTEIETCVECSAKNLKNISELFYYAQKAVLHPTGPLYCPEEKE
Sbjct: 121 DLVEYSSMETILPIMNQYTEIETCVECSAKNLKNISELFYYAQKAVLHPTGPLYCPEEKE 180

Query: 181 MKPACIKALTRIFKISDQDNDGTLNDAELNFFQRICFNTPLAPQALEDVKNVVRKHISDG 240
           MKPACIKALTRIFKISDQDNDGTLNDAELNFFQRICFNTPLAPQALEDVKNVVRKHISDG
Sbjct: 181 MKPACIKALTRIFKISDQDNDGTLNDAELNFFQRICFNTPLAPQALEDVKNVVRKHISDG 240

Query: 241 VADSGLTLKGFLFLHTLFIQRGRHETTWTVLRRFGYDDDLDLTPEYLFPLLKIPPDCTTE 300
           VADSGLTLKGFLFLHTLFIQRGRHETTWTVLRRFGYDDDLDLTPEYLFPLLKIPPDCTTE
Sbjct: 241 VADSGLTLKGFLFLHTLFIQRGRHETTWTVLRRFGYDDDLDLTPEYLFPLLKIPPDCTTE 300

Query: 301 LNHHAYLFLQSTFDKHDLDRDCALSPDELKDLFKVFPYIPWGPDVNNTVCTNERGWITYQ 360
           LNHHAYLFLQSTFDKHDLDRDCALSPDELKDLFKVFPYIPWGPDVNNTVCTNERGWITYQ
Sbjct: 301 LNHHAYLFLQSTFDKHDLDRDCALSPDELKDLFKVFPYIPWGPDVNNTVCTNERGWITYQ 360

Query: 361 GFLSQWTLTTYLDVQRCLEYLGYLGYSILTEQESQASAVTVTRDKKIDLQKKQTQRNVFR 420
           GFLSQWTLTTYLDVQRCLEYLGYLGYSILTEQESQASAVTVTRDKKIDLQKKQTQRNVFR
Sbjct: 361 GFLSQWTLTTYLDVQRCLEYLGYLGYSILTEQESQASAVTVTRDKKIDLQKKQTQRNVFR 420

Query: 421 CNVIGVKNCGKSGVLQALLGRNLMRQKKIREDHKSYYAINTVYVYGQEKYLLLHDISESE 480
           CNVIGVKNCGKSGVLQALLGRNLMRQKKIREDHKSYYAINTVYVYGQEKYLLLHDISESE
Sbjct: 421 CNVIGVKNCGKSGVLQALLGRNLMRQKKIREDHKSYYAINTVYVYGQEKYLLLHDISESE 480

Query: 481 FLTEAEIICDVVCLVYDVSNPKSFEYCARIFKQHFMDSRIPCLIVAAKSDLHEVKQEYSI 540
           FLTEAEIICDVVCLVYDVSNPKSFEYCARIFKQHFMDSRIPCLIVAAKSDLHEVKQEYSI
Sbjct: 481 FLTEAEIICDVVCLVYDVSNPKSFEYCARIFKQHFMDSRIPCLIVAAKSDLHEVKQEYSI 540

Query: 541 SPTDFCRKHKMPPPQAFTCNTADAPSKDIFVKLTTMAMYPHVTQADLKSSTFWLRASFGA 600
           SPTDFCRKHKMPPPQAFTCNTADAPSKDIFVKLTTMAMYPHVTQADLKSSTFWLRASFGA
Sbjct: 541 SPTDFCRKHKMPPPQAFTCNTADAPSKDIFVKLTTMAMYPHVTQADLKSSTFWLRASFGA 600

Query: 601 TVFAVLGFAMYKALLKQR 618
           TVFAVLGFAMYKALLKQR
Sbjct: 601 TVFAVLGFAMYKALLKQR 618


>gi|75750476 ras homolog gene family, member T1 isoform 2 [Homo
           sapiens]
          Length = 659

 Score = 1240 bits (3209), Expect = 0.0
 Identities = 618/659 (93%), Positives = 618/659 (93%), Gaps = 41/659 (6%)

Query: 1   MKKDVRILLVGEPRVGKTSLIMSLVSEEFPEEVPPRAEEITIPADVTPERVPTHIVDYSE 60
           MKKDVRILLVGEPRVGKTSLIMSLVSEEFPEEVPPRAEEITIPADVTPERVPTHIVDYSE
Sbjct: 1   MKKDVRILLVGEPRVGKTSLIMSLVSEEFPEEVPPRAEEITIPADVTPERVPTHIVDYSE 60

Query: 61  AEQSDEQLHQEISQANVICIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILVGNKS 120
           AEQSDEQLHQEISQANVICIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILVGNKS
Sbjct: 61  AEQSDEQLHQEISQANVICIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILVGNKS 120

Query: 121 DLVEYSSMETILPIMNQYTEIETCVECSAKNLKNISELFYYAQKAVLHPTGPLYCPEEKE 180
           DLVEYSSMETILPIMNQYTEIETCVECSAKNLKNISELFYYAQKAVLHPTGPLYCPEEKE
Sbjct: 121 DLVEYSSMETILPIMNQYTEIETCVECSAKNLKNISELFYYAQKAVLHPTGPLYCPEEKE 180

Query: 181 MKPACIKALTRIFKISDQDNDGTLNDAELNFFQRICFNTPLAPQALEDVKNVVRKHISDG 240
           MKPACIKALTRIFKISDQDNDGTLNDAELNFFQRICFNTPLAPQALEDVKNVVRKHISDG
Sbjct: 181 MKPACIKALTRIFKISDQDNDGTLNDAELNFFQRICFNTPLAPQALEDVKNVVRKHISDG 240

Query: 241 VADSGLTLKGFLFLHTLFIQRGRHETTWTVLRRFGYDDDLDLTPEYLFPLLKIPPDCTTE 300
           VADSGLTLKGFLFLHTLFIQRGRHETTWTVLRRFGYDDDLDLTPEYLFPLLKIPPDCTTE
Sbjct: 241 VADSGLTLKGFLFLHTLFIQRGRHETTWTVLRRFGYDDDLDLTPEYLFPLLKIPPDCTTE 300

Query: 301 LNHHAYLFLQSTFDKHDLDRDCALSPDELKDLFKVFPYIPWGPDVNNTVCTNERGWITYQ 360
           LNHHAYLFLQSTFDKHDLDRDCALSPDELKDLFKVFPYIPWGPDVNNTVCTNERGWITYQ
Sbjct: 301 LNHHAYLFLQSTFDKHDLDRDCALSPDELKDLFKVFPYIPWGPDVNNTVCTNERGWITYQ 360

Query: 361 GFLSQWTLTTYLDVQRCLEYLGYLGYSILTEQESQASAVTVTRDKKIDLQKKQTQRNVFR 420
           GFLSQWTLTTYLDVQRCLEYLGYLGYSILTEQESQASAVTVTRDKKIDLQKKQTQRNVFR
Sbjct: 361 GFLSQWTLTTYLDVQRCLEYLGYLGYSILTEQESQASAVTVTRDKKIDLQKKQTQRNVFR 420

Query: 421 CNVIGVKNCGKSGVLQALLGRNLMRQKKIREDHKSYYAINTVYVYGQEKYLLLHDISESE 480
           CNVIGVKNCGKSGVLQALLGRNLMRQKKIREDHKSYYAINTVYVYGQEKYLLLHDISESE
Sbjct: 421 CNVIGVKNCGKSGVLQALLGRNLMRQKKIREDHKSYYAINTVYVYGQEKYLLLHDISESE 480

Query: 481 FLTEAEIICDVVCLVYDVSNPKSFEYCARIFKQHFMDSRIPCLIVAAKSDLHEVKQEYSI 540
           FLTEAEIICDVVCLVYDVSNPKSFEYCARIFKQHFMDSRIPCLIVAAKSDLHEVKQEYSI
Sbjct: 481 FLTEAEIICDVVCLVYDVSNPKSFEYCARIFKQHFMDSRIPCLIVAAKSDLHEVKQEYSI 540

Query: 541 SPTDFCRKHKMPPPQAFTCNTADAPSKDIFVKLTTMAMYP-------------------- 580
           SPTDFCRKHKMPPPQAFTCNTADAPSKDIFVKLTTMAMYP                    
Sbjct: 541 SPTDFCRKHKMPPPQAFTCNTADAPSKDIFVKLTTMAMYPHARLRCMCTCNRCTFCICQN 600

Query: 581 ---------------------HVTQADLKSSTFWLRASFGATVFAVLGFAMYKALLKQR 618
                                HVTQADLKSSTFWLRASFGATVFAVLGFAMYKALLKQR
Sbjct: 601 FLNSDLLQSVKNKIFTAVLNRHVTQADLKSSTFWLRASFGATVFAVLGFAMYKALLKQR 659


>gi|75750480 ras homolog gene family, member T1 isoform 1 [Homo
           sapiens]
          Length = 691

 Score = 1187 bits (3070), Expect = 0.0
 Identities = 580/580 (100%), Positives = 580/580 (100%)

Query: 1   MKKDVRILLVGEPRVGKTSLIMSLVSEEFPEEVPPRAEEITIPADVTPERVPTHIVDYSE 60
           MKKDVRILLVGEPRVGKTSLIMSLVSEEFPEEVPPRAEEITIPADVTPERVPTHIVDYSE
Sbjct: 1   MKKDVRILLVGEPRVGKTSLIMSLVSEEFPEEVPPRAEEITIPADVTPERVPTHIVDYSE 60

Query: 61  AEQSDEQLHQEISQANVICIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILVGNKS 120
           AEQSDEQLHQEISQANVICIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILVGNKS
Sbjct: 61  AEQSDEQLHQEISQANVICIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILVGNKS 120

Query: 121 DLVEYSSMETILPIMNQYTEIETCVECSAKNLKNISELFYYAQKAVLHPTGPLYCPEEKE 180
           DLVEYSSMETILPIMNQYTEIETCVECSAKNLKNISELFYYAQKAVLHPTGPLYCPEEKE
Sbjct: 121 DLVEYSSMETILPIMNQYTEIETCVECSAKNLKNISELFYYAQKAVLHPTGPLYCPEEKE 180

Query: 181 MKPACIKALTRIFKISDQDNDGTLNDAELNFFQRICFNTPLAPQALEDVKNVVRKHISDG 240
           MKPACIKALTRIFKISDQDNDGTLNDAELNFFQRICFNTPLAPQALEDVKNVVRKHISDG
Sbjct: 181 MKPACIKALTRIFKISDQDNDGTLNDAELNFFQRICFNTPLAPQALEDVKNVVRKHISDG 240

Query: 241 VADSGLTLKGFLFLHTLFIQRGRHETTWTVLRRFGYDDDLDLTPEYLFPLLKIPPDCTTE 300
           VADSGLTLKGFLFLHTLFIQRGRHETTWTVLRRFGYDDDLDLTPEYLFPLLKIPPDCTTE
Sbjct: 241 VADSGLTLKGFLFLHTLFIQRGRHETTWTVLRRFGYDDDLDLTPEYLFPLLKIPPDCTTE 300

Query: 301 LNHHAYLFLQSTFDKHDLDRDCALSPDELKDLFKVFPYIPWGPDVNNTVCTNERGWITYQ 360
           LNHHAYLFLQSTFDKHDLDRDCALSPDELKDLFKVFPYIPWGPDVNNTVCTNERGWITYQ
Sbjct: 301 LNHHAYLFLQSTFDKHDLDRDCALSPDELKDLFKVFPYIPWGPDVNNTVCTNERGWITYQ 360

Query: 361 GFLSQWTLTTYLDVQRCLEYLGYLGYSILTEQESQASAVTVTRDKKIDLQKKQTQRNVFR 420
           GFLSQWTLTTYLDVQRCLEYLGYLGYSILTEQESQASAVTVTRDKKIDLQKKQTQRNVFR
Sbjct: 361 GFLSQWTLTTYLDVQRCLEYLGYLGYSILTEQESQASAVTVTRDKKIDLQKKQTQRNVFR 420

Query: 421 CNVIGVKNCGKSGVLQALLGRNLMRQKKIREDHKSYYAINTVYVYGQEKYLLLHDISESE 480
           CNVIGVKNCGKSGVLQALLGRNLMRQKKIREDHKSYYAINTVYVYGQEKYLLLHDISESE
Sbjct: 421 CNVIGVKNCGKSGVLQALLGRNLMRQKKIREDHKSYYAINTVYVYGQEKYLLLHDISESE 480

Query: 481 FLTEAEIICDVVCLVYDVSNPKSFEYCARIFKQHFMDSRIPCLIVAAKSDLHEVKQEYSI 540
           FLTEAEIICDVVCLVYDVSNPKSFEYCARIFKQHFMDSRIPCLIVAAKSDLHEVKQEYSI
Sbjct: 481 FLTEAEIICDVVCLVYDVSNPKSFEYCARIFKQHFMDSRIPCLIVAAKSDLHEVKQEYSI 540

Query: 541 SPTDFCRKHKMPPPQAFTCNTADAPSKDIFVKLTTMAMYP 580
           SPTDFCRKHKMPPPQAFTCNTADAPSKDIFVKLTTMAMYP
Sbjct: 541 SPTDFCRKHKMPPPQAFTCNTADAPSKDIFVKLTTMAMYP 580



 Score = 80.9 bits (198), Expect = 3e-15
 Identities = 40/47 (85%), Positives = 42/47 (89%)

Query: 572 KLTTMAMYPHVTQADLKSSTFWLRASFGATVFAVLGFAMYKALLKQR 618
           K+ T  +  HVTQADLKSSTFWLRASFGATVFAVLGFAMYKALLKQR
Sbjct: 645 KIFTAVLNRHVTQADLKSSTFWLRASFGATVFAVLGFAMYKALLKQR 691


>gi|20270303 ras homolog gene family, member T2 [Homo sapiens]
          Length = 618

 Score =  749 bits (1934), Expect = 0.0
 Identities = 372/622 (59%), Positives = 468/622 (75%), Gaps = 8/622 (1%)

Query: 1   MKKDVRILLVGEPRVGKTSLIMSLVSEEFPEEVPPRAEEITIPADVTPERVPTHIVDYSE 60
           M++DVRILL+GE +VGKTSLI+SLV EEFPEEVPPRAEEITIPADVTPE+VPTHIVDYSE
Sbjct: 1   MRRDVRILLLGEAQVGKTSLILSLVGEEFPEEVPPRAEEITIPADVTPEKVPTHIVDYSE 60

Query: 61  AEQSDEQLHQEISQANVICIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILVGNKS 120
           AEQ+DE+L +EI +ANV+C+VY V+ + +I+K+ ++WIPL+N  T +  R+P+ILVGNKS
Sbjct: 61  AEQTDEELREEIHKANVVCVVYDVSEEATIEKIRTKWIPLVNGGTTQGPRVPIILVGNKS 120

Query: 121 DLVEYSSMETILPIMNQYTEIETCVECSAKNLKNISELFYYAQKAVLHPTGPLYCPEEKE 180
           DL   SSME +LPIM+Q+ EIETCVECSAKNL+NISELFYYAQKAVLHPT PLY PE K+
Sbjct: 121 DLRSGSSMEAVLPIMSQFPEIETCVECSAKNLRNISELFYYAQKAVLHPTAPLYDPEAKQ 180

Query: 181 MKPACIKALTRIFKISDQDNDGTLNDAELNFFQRICFNTPLAPQALEDVKNVVRKHISDG 240
           ++PAC +ALTRIF++SDQD D  L+D ELN FQ+ CF  PLAPQALEDVK VV ++++ G
Sbjct: 181 LRPACAQALTRIFRLSDQDLDQALSDEELNAFQKSCFGHPLAPQALEDVKTVVCRNVAGG 240

Query: 241 VADSGLTLKGFLFLHTLFIQRGRHETTWTVLRRFGYDDDLDLTPEYLFPLLKIPPDCTTE 300
           V +  LTL GFLFL+TLFIQRGRHETTWT+LRRFGY D L+LT +YL PL+ +PP C+TE
Sbjct: 241 VREDRLTLDGFLFLNTLFIQRGRHETTWTILRRFGYSDALELTADYLSPLIHVPPGCSTE 300

Query: 301 LNHHAYLFLQSTFDKHDLDRDCALSPDELKDLFKVFPYIPWGPDVNNTVCTNERGWITYQ 360
           LNH  Y F+Q  F+KHD DRD ALSP EL+ LF VFP  PWGP++  TV T E G +   
Sbjct: 301 LNHLGYQFVQRVFEKHDQDRDGALSPVELQSLFSVFPAAPWGPELPRTVRT-EAGRLPLH 359

Query: 361 GFLSQWTLTTYLDVQRCLEYLGYLGYSILTEQESQASAVTVTRDKKIDLQKKQTQRNVFR 420
           G+L QWTL TYLDV+ CL +LGYLGY  L EQ+ QA A+TVTR+K++D +K QTQR+V  
Sbjct: 360 GYLCQWTLVTYLDVRSCLGHLGYLGYPTLCEQD-QAHAITVTREKRLDQEKGQTQRSVLL 418

Query: 421 CNVIGVKNCGKSGVLQALLGRNLMRQKKIREDHKSYYAINTVYVYGQEKYLLLHDISESE 480
           C V+G +  GKS  LQA LGR L  Q     +    YAI+TV V GQEKYL+L ++    
Sbjct: 419 CKVVGARGVGKSAFLQAFLGRGLGHQD--TREQPPGYAIDTVQVNGQEKYLILCEVGTDG 476

Query: 481 FL-TEAEIICDVVCLVYDVSNPKSFEYCARIFKQHFMDSRIPCLIVAAKSDLHEVKQEYS 539
            L T  +  CDV CL++D S+PKSF +CA ++K H+MD + PCL V++K+DL E      
Sbjct: 477 LLATSLDATCDVACLMFDGSDPKSFAHCASVYKHHYMDGQTPCLFVSSKADLPEGVAVSG 536

Query: 540 ISPTDFCRKHKMPPPQAFTCNTADAPSKDIFVKLTTMAMYPHVTQADLKSSTFWLRASF- 598
            SP +FCRKH++P P  F+C     PS  IF +L TMA +PH+  A+L  S+FWLR    
Sbjct: 537 PSPAEFCRKHRLPAPVPFSCAGPAEPSTTIFTQLATMAAFPHLVHAELHPSSFWLRGLLG 596

Query: 599 --GATVFAVLGFAMYKALLKQR 618
             GA V AVL F++Y+ L+K +
Sbjct: 597 VVGAAVAAVLSFSLYRVLVKSQ 618


>gi|38016957 ras homolog gene family, member F [Homo sapiens]
          Length = 211

 Score = 67.0 bits (162), Expect = 5e-11
 Identities = 50/180 (27%), Positives = 82/180 (45%), Gaps = 17/180 (9%)

Query: 2   KKDVRILLVGEPRVGKTSLIMSLVSEEFPEEVPPRA-EEITIPADVTPERVPTHIVDYSE 60
           +K+++I++VG+   GKTSL+M      FPE   P   E+ T    V  + V  ++ D + 
Sbjct: 17  RKELKIVIVGDGGCGKTSLLMVYSQGSFPEHYAPSVFEKYTASVTVGSKEVTLNLYDTAG 76

Query: 61  AEQSDEQLHQEISQANVICIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILVGNKS 120
            E  D          +++ I Y V N  S D V  +W P   E T     +P++L+G K+
Sbjct: 77  QEDYDRLRPLSYQNTHLVLICYDVMNPTSYDNVLIKWFP---EVTHFCRGIPMVLIGCKT 133

Query: 121 DL---------VEYSSMETILPIMN----QYTEIETCVECSAKNLKNISELFYYAQKAVL 167
           DL         +  + +E I  +      +       +ECSAK  +N+ ++F  A K  L
Sbjct: 134 DLRKDKEQLRKLRAAQLEPITYMQGLSACEQIRAALYLECSAKFRENVEDVFREAAKVAL 193


>gi|7656900 ras homolog D [Homo sapiens]
          Length = 210

 Score = 65.5 bits (158), Expect = 1e-10
 Identities = 51/183 (27%), Positives = 83/183 (45%), Gaps = 17/183 (9%)

Query: 3   KDVRILLVGEPRVGKTSLIMSLVSEEFPEEVPPRA-EEITIPADVTPERVPTHIVDYSEA 61
           + V+++LVG+   GKTSL+M      FPE   P   E   +   V  + V  HI D +  
Sbjct: 16  RSVKVVLVGDGGCGKTSLLMVFADGAFPESYTPTVFERYMVNLQVKGKPVHLHIWDTAGQ 75

Query: 62  EQSDEQLHQEISQANVICIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILVGNKSD 121
           +  D         A+V+ + + V + +S D + +RW P +N    K   +P+I+VG K+D
Sbjct: 76  DDYDRLRPLFYPDASVLLLCFDVTSPNSFDNIFNRWYPEVNHFCKK---VPIIVVGCKTD 132

Query: 122 LVEYSSMETIL------PI-------MNQYTEIETCVECSAKNLKNISELFYYAQKAVLH 168
           L +  S+   L      P+       M +       +ECSA+   N+  +F  A +  L 
Sbjct: 133 LRKDKSLVNKLRRNGLEPVTYHRGQEMARSVGAVAYLECSARLHDNVHAVFQEAAEVALS 192

Query: 169 PTG 171
             G
Sbjct: 193 SRG 195


>gi|4757764 ras homolog gene family, member B [Homo sapiens]
          Length = 196

 Score = 63.2 bits (152), Expect = 7e-10
 Identities = 46/176 (26%), Positives = 80/176 (45%), Gaps = 17/176 (9%)

Query: 6   RILLVGEPRVGKTSLIMSLVSEEFPE-EVPPRAEEITIPADVTPERVPTHIVDYSEAEQS 64
           ++++VG+   GKT L++    +EFPE  VP   E      +V  ++V   + D +  E  
Sbjct: 7   KLVVVGDGACGKTCLLIVFSKDEFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDY 66

Query: 65  DEQLHQEISQANVICIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILVGNKSDLVE 124
           D          +VI + ++V++  S++ +  +W+P +         +P+ILV NK DL  
Sbjct: 67  DRLRPLSYPDTDVILMCFSVDSPDSLENIPEKWVPEVKHFC---PNVPIILVANKKDLRS 123

Query: 125 YSSMETILPIMNQ-------------YTEIETCVECSAKNLKNISELFYYAQKAVL 167
              + T L  M Q               +    +ECSAK  + + E+F  A +A L
Sbjct: 124 DEHVRTELARMKQEPVRTDDGRAMAVRIQAYDYLECSAKTKEGVREVFETATRAAL 179


>gi|11034843 ras homolog gene family, member U [Homo sapiens]
          Length = 258

 Score = 60.8 bits (146), Expect = 3e-09
 Identities = 43/171 (25%), Positives = 79/171 (46%), Gaps = 17/171 (9%)

Query: 3   KDVRILLVGEPRVGKTSLIMSLVSEEFPEE-VPPRAEEITIPADVTPERVPTHIVDYSEA 61
           + V+ +LVG+  VGKTSL++S  +  +P E +P   +  +    V    V   + D +  
Sbjct: 48  RGVKCVLVGDGAVGKTSLVVSYTTNGYPTEYIPTAFDNFSAVVSVDGRPVRLQLCDTAGQ 107

Query: 62  EQSDEQLHQEISQANVICIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILVGNKSD 121
           ++ D+      +  ++  + ++V +  S   V+ +W+P I     K    P+ILVG +SD
Sbjct: 108 DEFDKLRPLCYTNTDIFLLCFSVVSPSSFQNVSEKWVPEIRCHCPK---APIILVGTQSD 164

Query: 122 LVEYSSM-------------ETILPIMNQYTEIETCVECSAKNLKNISELF 159
           L E   +             E    +  +  +  + +ECSA   KN+ E+F
Sbjct: 165 LREDVKVLIELDKCKEKPVPEEAAKLCAEEIKAASYIECSALTQKNLKEVF 215


>gi|46249393 ras homolog gene family, member G [Homo sapiens]
          Length = 191

 Score = 60.1 bits (144), Expect = 6e-09
 Identities = 46/182 (25%), Positives = 81/182 (44%), Gaps = 17/182 (9%)

Query: 3   KDVRILLVGEPRVGKTSLIMSLVSEEFPEE-VPPRAEEITIPADVTPERVPTHIVDYSEA 61
           + ++ ++VG+  VGKT L++   +  FP+E +P   +  +  + V    V  ++ D +  
Sbjct: 2   QSIKCVVVGDGAVGKTCLLICYTTNAFPKEYIPTVFDNYSAQSAVDGRTVNLNLWDTAGQ 61

Query: 62  EQSDEQLHQEISQANVICIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILVGNKSD 121
           E+ D        Q NV  I +++ +  S + V  +W P +         +P++LVG K D
Sbjct: 62  EEYDRLRTLSYPQTNVFVICFSIASPPSYENVRHKWHPEVCHHCPD---VPILLVGTKKD 118

Query: 122 L---------VEYSSMETILPIMNQ----YTEIETCVECSAKNLKNISELFYYAQKAVLH 168
           L         ++      I P   Q           +ECSA     + E+F  A +AVL+
Sbjct: 119 LRAQPDTLRRLKEQGQAPITPQQGQALAKQIHAVRYLECSALQQDGVKEVFAEAVRAVLN 178

Query: 169 PT 170
           PT
Sbjct: 179 PT 180


>gi|16357472 cell division cycle 42 isoform 2 [Homo sapiens]
          Length = 191

 Score = 59.7 bits (143), Expect = 8e-09
 Identities = 50/196 (25%), Positives = 82/196 (41%), Gaps = 23/196 (11%)

Query: 5   VRILLVGEPRVGKTSLIMSLVSEEFPEE-VPPRAEEITIPADVTPERVPTHIVDYSEAEQ 63
           ++ ++VG+  VGKT L++S  + +FP E VP   +   +   +  E     + D +  E 
Sbjct: 4   IKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAGQED 63

Query: 64  SDEQLHQEISQANVICIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILVGNKSDL- 122
            D        Q +V  + ++V +  S + V  +W+P I     K    P +LVG + DL 
Sbjct: 64  YDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPK---TPFLLVGTQIDLR 120

Query: 123 -----VEYSSMETILPIMNQYTE-------IETCVECSAKNLKNISELFYYAQKAVLHPT 170
                +E  +     PI  +  E           VECSA   + +  +F  A  A L P 
Sbjct: 121 DDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQRGLKNVFDEAILAALEP- 179

Query: 171 GPLYCPEEKEMKPACI 186
                PE +  +  CI
Sbjct: 180 -----PETQPKRKCCI 190


>gi|89903012 cell division cycle 42 isoform 1 [Homo sapiens]
          Length = 191

 Score = 59.7 bits (143), Expect = 8e-09
 Identities = 48/182 (26%), Positives = 77/182 (42%), Gaps = 17/182 (9%)

Query: 5   VRILLVGEPRVGKTSLIMSLVSEEFPEE-VPPRAEEITIPADVTPERVPTHIVDYSEAEQ 63
           ++ ++VG+  VGKT L++S  + +FP E VP   +   +   +  E     + D +  E 
Sbjct: 4   IKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAGQED 63

Query: 64  SDEQLHQEISQANVICIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILVGNKSDL- 122
            D        Q +V  + ++V +  S + V  +W+P I     K    P +LVG + DL 
Sbjct: 64  YDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPK---TPFLLVGTQIDLR 120

Query: 123 -----VEYSSMETILPIMNQYTE-------IETCVECSAKNLKNISELFYYAQKAVLHPT 170
                +E  +     PI  +  E           VECSA   K +  +F  A  A L P 
Sbjct: 121 DDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQKGLKNVFDEAILAALEPP 180

Query: 171 GP 172
            P
Sbjct: 181 EP 182


>gi|4757952 cell division cycle 42 isoform 1 [Homo sapiens]
          Length = 191

 Score = 59.7 bits (143), Expect = 8e-09
 Identities = 48/182 (26%), Positives = 77/182 (42%), Gaps = 17/182 (9%)

Query: 5   VRILLVGEPRVGKTSLIMSLVSEEFPEE-VPPRAEEITIPADVTPERVPTHIVDYSEAEQ 63
           ++ ++VG+  VGKT L++S  + +FP E VP   +   +   +  E     + D +  E 
Sbjct: 4   IKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAGQED 63

Query: 64  SDEQLHQEISQANVICIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILVGNKSDL- 122
            D        Q +V  + ++V +  S + V  +W+P I     K    P +LVG + DL 
Sbjct: 64  YDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPK---TPFLLVGTQIDLR 120

Query: 123 -----VEYSSMETILPIMNQYTE-------IETCVECSAKNLKNISELFYYAQKAVLHPT 170
                +E  +     PI  +  E           VECSA   K +  +F  A  A L P 
Sbjct: 121 DDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQKGLKNVFDEAILAALEPP 180

Query: 171 GP 172
            P
Sbjct: 181 EP 182


>gi|50263042 ras-like protein TC10 [Homo sapiens]
          Length = 205

 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 49/179 (27%), Positives = 77/179 (43%), Gaps = 17/179 (9%)

Query: 5   VRILLVGEPRVGKTSLIMSLVSEEFPEE-VPPRAEEITIPADVTPERVPTHIVDYSEAEQ 63
           ++ ++VG+  VGKT L+MS  ++ FPEE VP   +   +   V  ++    + D +  E 
Sbjct: 10  LKCVVVGDGAVGKTCLLMSYANDAFPEEYVPTVFDHYAVSVTVGGKQYLLGLYDTAGQED 69

Query: 64  SDEQLHQEISQANVICIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILVGNKSDLV 123
            D          +V  I ++V N  S   V   W+P + E       +P +L+G + DL 
Sbjct: 70  YDRLRPLSYPMTDVFLICFSVVNPASFQNVKEEWVPELKEYA---PNVPFLLIGTQIDLR 126

Query: 124 EYSSMETILPIMNQ-----------YTEIETC--VECSAKNLKNISELFYYAQKAVLHP 169
           +       L  M +             EI  C  VECSA   K +  +F  A  A+L P
Sbjct: 127 DDPKTLARLNDMKEKPICVEQGQKLAKEIGACCYVECSALTQKGLKTVFDEAIIAILTP 185


>gi|4506381 ras-related C3 botulinum toxin substrate 2 [Homo
           sapiens]
          Length = 192

 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 53/197 (26%), Positives = 93/197 (47%), Gaps = 27/197 (13%)

Query: 5   VRILLVGEPRVGKTSLIMSLVSEEFPEEVPPRAEEITIPADVTPERVPTHIVDYSEAEQS 64
           ++ ++VG+  VGKT L++S  +  FP E  P   +    A+V  +  P ++  +  A Q 
Sbjct: 4   IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFD-NYSANVMVDSKPVNLGLWDTAGQE 62

Query: 65  DEQLHQEIS--QANVICIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILVGNKSDL 122
           D    + +S  Q +V  I +++ +  S + V ++W P +          P+ILVG K DL
Sbjct: 63  DYDRLRPLSYPQTDVFLICFSLVSPASYENVRAKWFPEVRHHCPS---TPIILVGTKLDL 119

Query: 123 ------VEYSSMETILPI-----MNQYTEIETC--VECSAKNLKNISELFYYAQKAVLHP 169
                 +E    + + PI     +    EI++   +ECSA   + +  +F  A +AVL  
Sbjct: 120 RDDKDTIEKLKEKKLAPITYPQGLALAKEIDSVKYLECSALTQRGLKTVFDEAIRAVL-- 177

Query: 170 TGPLYCPE-EKEMKPAC 185
                CP+  ++ K AC
Sbjct: 178 -----CPQPTRQQKRAC 189


>gi|9845511 ras-related C3 botulinum toxin substrate 1 isoform Rac1
           [Homo sapiens]
          Length = 192

 Score = 57.8 bits (138), Expect = 3e-08
 Identities = 52/197 (26%), Positives = 89/197 (45%), Gaps = 25/197 (12%)

Query: 5   VRILLVGEPRVGKTSLIMSLVSEEFPEEVPPRAEEITIPADVTPERVPTHIVDYSEAEQS 64
           ++ ++VG+  VGKT L++S  +  FP E  P   +    A+V  +  P ++  +  A Q 
Sbjct: 4   IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFD-NYSANVMVDGKPVNLGLWDTAGQE 62

Query: 65  DEQLHQEIS--QANVICIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILVGNKSDL 122
           D    + +S  Q +V  I +++ +  S + V ++W P +          P+ILVG K DL
Sbjct: 63  DYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHC---PNTPIILVGTKLDL 119

Query: 123 ------VEYSSMETILPI-------MNQYTEIETCVECSAKNLKNISELFYYAQKAVLHP 169
                 +E    + + PI       M +       +ECSA   + +  +F  A +AVL P
Sbjct: 120 RDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCP 179

Query: 170 TGPLYCPEEKEMKPACI 186
                 P  K+ K  C+
Sbjct: 180 ------PPVKKRKRKCL 190


>gi|111494251 ras homolog gene family, member C precursor [Homo
           sapiens]
          Length = 193

 Score = 57.8 bits (138), Expect = 3e-08
 Identities = 44/176 (25%), Positives = 78/176 (44%), Gaps = 17/176 (9%)

Query: 6   RILLVGEPRVGKTSLIMSLVSEEFPE-EVPPRAEEITIPADVTPERVPTHIVDYSEAEQS 64
           ++++VG+   GKT L++    ++FPE  VP   E      +V  ++V   + D +  E  
Sbjct: 7   KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDGKQVELALWDTAGQEDY 66

Query: 65  DEQLHQEISQANVICIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILVGNKSDLVE 124
           D          +VI + +++++  S++ +  +W P +         +P+ILVGNK DL +
Sbjct: 67  DRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFC---PNVPIILVGNKKDLRQ 123

Query: 125 YSSMETILPIMNQ-------------YTEIETCVECSAKNLKNISELFYYAQKAVL 167
                  L  M Q                    +ECSAK  + + E+F  A +A L
Sbjct: 124 DEHTRRELAKMKQEPVRSEEGRDMANRISAFGYLECSAKTKEGVREVFEMATRAGL 179


>gi|111494248 ras homolog gene family, member C precursor [Homo
           sapiens]
          Length = 193

 Score = 57.8 bits (138), Expect = 3e-08
 Identities = 44/176 (25%), Positives = 78/176 (44%), Gaps = 17/176 (9%)

Query: 6   RILLVGEPRVGKTSLIMSLVSEEFPE-EVPPRAEEITIPADVTPERVPTHIVDYSEAEQS 64
           ++++VG+   GKT L++    ++FPE  VP   E      +V  ++V   + D +  E  
Sbjct: 7   KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDGKQVELALWDTAGQEDY 66

Query: 65  DEQLHQEISQANVICIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILVGNKSDLVE 124
           D          +VI + +++++  S++ +  +W P +         +P+ILVGNK DL +
Sbjct: 67  DRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFC---PNVPIILVGNKKDLRQ 123

Query: 125 YSSMETILPIMNQ-------------YTEIETCVECSAKNLKNISELFYYAQKAVL 167
                  L  M Q                    +ECSAK  + + E+F  A +A L
Sbjct: 124 DEHTRRELAKMKQEPVRSEEGRDMANRISAFGYLECSAKTKEGVREVFEMATRAGL 179


>gi|28395033 ras homolog gene family, member C precursor [Homo
           sapiens]
          Length = 193

 Score = 57.8 bits (138), Expect = 3e-08
 Identities = 44/176 (25%), Positives = 78/176 (44%), Gaps = 17/176 (9%)

Query: 6   RILLVGEPRVGKTSLIMSLVSEEFPE-EVPPRAEEITIPADVTPERVPTHIVDYSEAEQS 64
           ++++VG+   GKT L++    ++FPE  VP   E      +V  ++V   + D +  E  
Sbjct: 7   KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDGKQVELALWDTAGQEDY 66

Query: 65  DEQLHQEISQANVICIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILVGNKSDLVE 124
           D          +VI + +++++  S++ +  +W P +         +P+ILVGNK DL +
Sbjct: 67  DRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFC---PNVPIILVGNKKDLRQ 123

Query: 125 YSSMETILPIMNQ-------------YTEIETCVECSAKNLKNISELFYYAQKAVL 167
                  L  M Q                    +ECSAK  + + E+F  A +A L
Sbjct: 124 DEHTRRELAKMKQEPVRSEEGRDMANRISAFGYLECSAKTKEGVREVFEMATRAGL 179


>gi|10835049 ras homolog gene family, member A [Homo sapiens]
          Length = 193

 Score = 57.4 bits (137), Expect = 4e-08
 Identities = 44/176 (25%), Positives = 76/176 (43%), Gaps = 17/176 (9%)

Query: 6   RILLVGEPRVGKTSLIMSLVSEEFPE-EVPPRAEEITIPADVTPERVPTHIVDYSEAEQS 64
           ++++VG+   GKT L++    ++FPE  VP   E      +V  ++V   + D +  E  
Sbjct: 7   KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDY 66

Query: 65  DEQLHQEISQANVICIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILVGNKSDLVE 124
           D          +VI + +++++  S++ +  +W P +         +P+ILVGNK DL  
Sbjct: 67  DRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFC---PNVPIILVGNKKDLRN 123

Query: 125 YSSMETILPIMNQYTEIET-------------CVECSAKNLKNISELFYYAQKAVL 167
                  L  M Q                    +ECSAK    + E+F  A +A L
Sbjct: 124 DEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAAL 179


>gi|4757772 DIRAS family, GTP-binding RAS-like 3 [Homo sapiens]
          Length = 229

 Score = 56.6 bits (135), Expect = 7e-08
 Identities = 49/190 (25%), Positives = 83/190 (43%), Gaps = 18/190 (9%)

Query: 3   KDVRILLVGEPRVGKTSLIMSLVSEEFPEEVPPRAEEITIPADVTPERVPT-HIVDYSEA 61
           +D R+++VG   VGK++L+    S  F  E  P  E            V + HI D    
Sbjct: 36  RDYRVVVVGTAGVGKSTLLHKWASGNFRHEYLPTIENTYCQLLGCSHGVLSLHITDSKSG 95

Query: 62  EQSDEQLHQEISQANVICIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILVGNKSD 121
           + +       I++ +   +VY+V  K +++++ + +  +   + +   + P++LVGNKSD
Sbjct: 96  DGNRALQRHVIARGHAFVLVYSVTKKETLEELKAFYELICKIKGNNLHKFPIVLVGNKSD 155

Query: 122 LVEYSSMETILPIMNQYTEIETC--------VECSAKNLKNISELFYYAQKAVLHPTGPL 173
               +  E  L       +  TC        +E SAK   N+ ELF+        PT  L
Sbjct: 156 ---DTHREVAL------NDGATCAMEWNCAFMEISAKTDVNVQELFHMLLNYKKKPTTGL 206

Query: 174 YCPEEKEMKP 183
             PE+K   P
Sbjct: 207 QEPEKKSQMP 216


>gi|16903164 ras homolog gene family, member J [Homo sapiens]
          Length = 214

 Score = 56.6 bits (135), Expect = 7e-08
 Identities = 51/185 (27%), Positives = 81/185 (43%), Gaps = 23/185 (12%)

Query: 2   KKDVRILLVGEPRVGKTSLIMSLVSEEFPEE-VPPRAEEITIPADVTPERVPTHIVD-YS 59
           KK ++ ++VG+  VGKT L+MS  ++ FPEE VP   +   +   V  ++   H++  Y 
Sbjct: 19  KKMLKCVVVGDGAVGKTCLLMSYANDAFPEEYVPTVFDHYAVTVTVGGKQ---HLLGLYD 75

Query: 60  EAEQSDEQLHQEISQAN--VICIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILVG 117
            A Q D    + +S  N  V  I ++V N  S   V   W+P   E  D    +P +L+G
Sbjct: 76  TAGQEDYNQLRPLSYPNTDVFLICFSVVNPASYHNVQEEWVP---ELKDCMPHVPYVLIG 132

Query: 118 NKSDLVEYSSMETILPIMNQ-------------YTEIETCVECSAKNLKNISELFYYAQK 164
            + DL +       L  M +                 +  +ECSA   K +  +F  A  
Sbjct: 133 TQIDLRDDPKTLARLLYMKEKPLTYEHGVKLAKAIGAQCYLECSALTQKGLKAVFDEAIL 192

Query: 165 AVLHP 169
            + HP
Sbjct: 193 TIFHP 197


>gi|229577148 ras homolog gene family, member V [Homo sapiens]
          Length = 236

 Score = 56.2 bits (134), Expect = 9e-08
 Identities = 51/203 (25%), Positives = 89/203 (43%), Gaps = 24/203 (11%)

Query: 5   VRILLVGEPRVGKTSLIMSLVSEEFPEEVPPRAEEITIPADVTPERVPTHIVDYSEAEQS 64
           ++ +LVG+  VGK+SLI+S     +P    P A + T    V  +  P  I  +  A Q 
Sbjct: 32  IKCVLVGDGAVGKSSLIVSYTCNGYPARYRPTALD-TFSVQVLVDGAPVRIELWDTAGQE 90

Query: 65  DEQLHQEI--SQANVICIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILVGNKSDL 122
           D    + +     +V    ++V    S   +T +W+P I      + + P++LVG ++DL
Sbjct: 91  DFDRLRSLCYPDTDVFLACFSVVQPSSFQNITEKWLPEIRTH---NPQAPVLLVGTQADL 147

Query: 123 ---------VEYSSMETILP---IMNQYTEIETC--VECSAKNLKNISELFYYAQKAVLH 168
                    ++    E  +P         +I  C  +ECSA   KN+ E+F  A  + + 
Sbjct: 148 RDDVNVLIQLDQGGREGPVPQPQAQGLAEKIRACCYLECSALTQKNLKEVFDSAILSAIE 207

Query: 169 PTGPLYCPEEKEMKPACIKALTR 191
               L    EK++    ++ L+R
Sbjct: 208 HKARL----EKKLNAKGVRTLSR 226


>gi|20070266 RAS-like GTP-binding protein REM [Homo sapiens]
          Length = 298

 Score = 56.2 bits (134), Expect = 9e-08
 Identities = 49/161 (30%), Positives = 78/161 (48%), Gaps = 13/161 (8%)

Query: 6   RILLVGEPRVGKTSLIMSLVSEE---FPEEVPPRAEEITIPADVTPERVPTHIVDYSEAE 62
           R++L+G+P VGKTSL      ++     E++     E T+  D   E     +VD  EAE
Sbjct: 82  RVVLLGDPGVGKTSLASLFAGKQERDLHEQLGEDVYERTLTVD--GEDTTLVVVDTWEAE 139

Query: 63  QSDEQLHQE--ISQANVICIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILVGNKS 120
           + D+   QE  +   +   IVY++ ++ S +  +   I L   RT +   +P+ILVGNK+
Sbjct: 140 KLDKSWSQESCLQGGSAYVIVYSIADRGSFESASELRIQL--RRTHQADHVPIILVGNKA 197

Query: 121 DLVEYSSMETILPIMNQYTEIETC--VECSAKNLKNISELF 159
           DL      E  +        +  C  +E SA    N++ELF
Sbjct: 198 DLAR--CREVSVEEGRACAVVFDCKFIETSATLQHNVAELF 236


>gi|4826962 ras-related C3 botulinum toxin substrate 3 (rho family,
           small GTP binding protein Rac3) [Homo sapiens]
          Length = 192

 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 51/190 (26%), Positives = 90/190 (47%), Gaps = 20/190 (10%)

Query: 5   VRILLVGEPRVGKTSLIMSLVSEEFPEEVPPRAEEITIPADVTPERVPTHIVDYSEAEQS 64
           ++ ++VG+  VGKT L++S  +  FP E  P   +    A+V  +  P ++  +  A Q 
Sbjct: 4   IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFD-NYSANVMVDGKPVNLGLWDTAGQE 62

Query: 65  DEQLHQEIS--QANVICIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILVGNKSDL 122
           D    + +S  Q +V  I +++ +  S + V ++W P +          P++LVG K DL
Sbjct: 63  DYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHC---PHTPILLVGTKLDL 119

Query: 123 ------VEYSSMETILPI-----MNQYTEIETC--VECSAKNLKNISELFYYAQKAVLHP 169
                 +E    + + PI     +    EI +   +ECSA   + +  +F  A +AVL P
Sbjct: 120 RDDKDTIERLRDKKLAPITYPQGLAMAREIGSVKYLECSALTQRGLKTVFDEAIRAVLCP 179

Query: 170 TGPLYCPEEK 179
             P+  P +K
Sbjct: 180 P-PVKKPGKK 188


>gi|22027486 RASD family, member 2 [Homo sapiens]
          Length = 266

 Score = 53.9 bits (128), Expect = 4e-07
 Identities = 39/168 (23%), Positives = 75/168 (44%), Gaps = 9/168 (5%)

Query: 2   KKDVRILLVGEPRVGKTSLIMSLVSEEFPEEVPPRAEEITIPA-DVTPERVPTHIVDYSE 60
           K   R++++G  RVGK+S++   ++  F ++  P  E+      ++  +     I+D S 
Sbjct: 17  KNSYRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKVYNIRGDMYQLDILDTSG 76

Query: 61  AEQSDEQLHQEISQANVICIVYAVNNKHSIDKVTSRWIPLIN------ERTDKDSRLPLI 114
                      I   +V  +V++++N+ S D+V      ++        +T + + LP++
Sbjct: 77  NHPFPAMRRLSILTGDVFILVFSLDNRESFDEVKRLQKQILEVKSCLKNKTKEAAELPMV 136

Query: 115 LVGNKSDLVEYSSMETILPIMNQYTEIETCV--ECSAKNLKNISELFY 160
           + GNK+D  E              +  E C   E SAK   N+ E+FY
Sbjct: 137 ICGNKNDHGELCRQVPTTEAELLVSGDENCAYFEVSAKKNTNVDEMFY 184



 Score = 29.6 bits (65), Expect = 8.6
 Identities = 35/137 (25%), Positives = 54/137 (39%), Gaps = 21/137 (15%)

Query: 416 RNVFRCNVIGVKNCGKSGVLQALLGRNLMRQ--KKIREDHKSYYAINTVYVYGQEKYLLL 473
           +N +R  V+G    GKS ++   L      Q    I + H+  Y I      G    L +
Sbjct: 17  KNSYRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKVYNIR-----GDMYQLDI 71

Query: 474 HDISESE---FLTEAEIIC-DVVCLVYDVSNPKSFEYCARIFKQHFMDSRIPCLIVAAKS 529
            D S +     +    I+  DV  LV+ + N +SF+   R+ KQ          I+  KS
Sbjct: 72  LDTSGNHPFPAMRRLSILTGDVFILVFSLDNRESFDEVKRLQKQ----------ILEVKS 121

Query: 530 DLHEVKQEYSISPTDFC 546
            L    +E +  P   C
Sbjct: 122 CLKNKTKEAAELPMVIC 138


>gi|21703367 Di-Ras2 [Homo sapiens]
          Length = 199

 Score = 52.8 bits (125), Expect = 9e-07
 Identities = 43/159 (27%), Positives = 73/159 (45%), Gaps = 6/159 (3%)

Query: 4   DVRILLVGEPRVGKTSLIMSLVSEEFPEEVPPRAEEITIPADVTPERVPT-HIVDYSEAE 62
           D R+ + G   VGK+SL++  V   F E   P  E+         + + T  I D + + 
Sbjct: 7   DYRVAVFGAGGVGKSSLVLRFVKGTFRESYIPTVEDTYRQVISCDKSICTLQITDTTGSH 66

Query: 63  QSDEQLHQEISQANVICIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILVGNKSDL 122
           Q        IS+ +   +VY++ ++ S++++   +  +   + D +S +P++LVGNK D 
Sbjct: 67  QFPAMQRLSISKGHAFILVYSITSRQSLEELKPIYEQICEIKGDVES-IPIMLVGNKCD- 124

Query: 123 VEYSSMETILPIMNQYTEIETC--VECSAKNLKNISELF 159
            E  S E              C  +E SAK   N+ ELF
Sbjct: 125 -ESPSREVQSSEAEALARTWKCAFMETSAKLNHNVKELF 162


>gi|4885069 ras homolog gene family, member E [Homo sapiens]
          Length = 244

 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 44/182 (24%), Positives = 84/182 (46%), Gaps = 22/182 (12%)

Query: 6   RILLVGEPRVGKTSLIMSLVSEEFPEE-VPPRAEEITIPADVTPERVPTHIVDYSEAEQS 64
           +I++VG+ + GKT+L+     + FPE  VP   E  T   ++  +R+   + D S +   
Sbjct: 25  KIVVVGDSQCGKTALLHVFAKDCFPENYVPTVFENYTASFEIDTQRIELSLWDTSGSPYY 84

Query: 65  DEQLHQEISQANVICIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILVGNKSDLVE 124
           D         ++ + I + ++   ++D V  +W   I E         ++LVG KSDL  
Sbjct: 85  DNVRPLSYPDSDAVLICFDISRPETLDSVLKKWKGEIQEFCPNTK---MLLVGCKSDL-- 139

Query: 125 YSSMETILPIMN-QYTEIE--------------TCVECSAKNLKN-ISELFYYAQKAVLH 168
            + + T++ + N + T +               T +ECSA   +N + ++F+ A  A ++
Sbjct: 140 RTDVSTLVELSNHRQTPVSYDQGANMAKQIGAATYIECSALQSENSVRDIFHVATLACVN 199

Query: 169 PT 170
            T
Sbjct: 200 KT 201


>gi|38201690 RAP2B, member of RAS oncogene family [Homo sapiens]
          Length = 183

 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 46/167 (27%), Positives = 78/167 (46%), Gaps = 21/167 (12%)

Query: 3   KDVRILLVGEPRVGKTSLIMSLVSEEFPEEVPPRAEEI---TIPADVTPERVPTHIVDYS 59
           ++ +++++G   VGK++L +  V+  F E+  P  E+     I  D +P  +   I+D +
Sbjct: 2   REYKVVVLGSGGVGKSALTVQFVTGSFIEKYDPTIEDFYRKEIEVDSSPSVL--EILDTA 59

Query: 60  EAEQSDEQLHQEISQANVICIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILVGNK 119
             EQ        I       +VY++ N+ S   +      +I  R  +  R+P+ILVGNK
Sbjct: 60  GTEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQII--RVKRYERVPMILVGNK 117

Query: 120 SDL-----VEYSSMETILPIMNQYTEIETC--VECSAKNLKNISELF 159
            DL     V Y   + +        E  +C  +E SAKN  ++ ELF
Sbjct: 118 VDLEGEREVSYGEGKAL-------AEEWSCPFMETSAKNKASVDELF 157


>gi|32483371 GTP-binding mitogen-induced T-cell protein [Homo
           sapiens]
          Length = 296

 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 50/162 (30%), Positives = 77/162 (47%), Gaps = 14/162 (8%)

Query: 6   RILLVGEPRVGKTSL--IMSLVSEEFPEEVPPRAE---EITIPADVTPERVPTHIVDYSE 60
           R++L+GE  VGK++L  I + V +    +     E   E T+  D   E     ++D  E
Sbjct: 77  RVVLIGEQGVGKSTLANIFAGVHDSMDSDCEVLGEDTYERTLMVD--GESATIILLDMWE 134

Query: 61  AEQSDEQLHQEISQA-NVICIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILVGNK 119
            +  +E LH    Q  +   IVY++ ++ S +K +   I L   R  +D  +P+ILVGNK
Sbjct: 135 NKGENEWLHDHCMQVGDAYLIVYSITDRASFEKASELRIQLRRARQTED--IPIILVGNK 192

Query: 120 SDLVEYSSMETILPIMNQYTEIETC--VECSAKNLKNISELF 159
           SDLV     E  +        +  C  +E SA    N+ ELF
Sbjct: 193 SDLVR--CREVSVSEGRACAVVFDCKFIETSAAVQHNVKELF 232


>gi|7706095 RAS-like, family 12 protein [Homo sapiens]
          Length = 266

 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 38/191 (19%), Positives = 86/191 (45%), Gaps = 19/191 (9%)

Query: 4   DVRILLVGEPRVGKTSLIMSLVSEEFPEEVPPRAEEITIPADVTPERVPTHIVDYSEAE- 62
           +V + ++G    GK++L +  +++ F  E  P  E+ T  ++ T +  P H+     A+ 
Sbjct: 20  EVNLAILGRRGAGKSALTVKFLTKRFISEYDPNLED-TYSSEETVDHQPVHLRVMDTADL 78

Query: 63  QSDEQLHQEISQANVICIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILVGNKSDL 122
            +     + ++ A+   +VY+V+++ S D  +S    L     +    +P +L+GNK D+
Sbjct: 79  DTPRNCERYLNWAHAFLVVYSVDSRQSFDSSSSYLELLALHAKETQRSIPALLLGNKLDM 138

Query: 123 VEYSSMETILPIMNQ------YTEIETCVECSAKNLKNISELFYYAQKAVLHP------T 170
            +Y  +     +         + E+  C++      +++  +F+ A +           T
Sbjct: 139 AQYRQVTKAEGVALAGRFGCLFFEVSACLD-----FEHVQHVFHEAVREARRELEKSPLT 193

Query: 171 GPLYCPEEKEM 181
            PL+  EE+ +
Sbjct: 194 RPLFISEERAL 204


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.136    0.411 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,557,944
Number of Sequences: 37866
Number of extensions: 1057299
Number of successful extensions: 3070
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 26
Number of HSP's successfully gapped in prelim test: 146
Number of HSP's that attempted gapping in prelim test: 2890
Number of HSP's gapped (non-prelim): 220
length of query: 618
length of database: 18,247,518
effective HSP length: 108
effective length of query: 510
effective length of database: 14,157,990
effective search space: 7220574900
effective search space used: 7220574900
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.