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Search of human proteins with 7524359
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7524359 paired box 7 isoform 2 [Homo sapiens]
(518 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7524359 paired box 7 isoform 2 [Homo sapiens] 1062 0.0
gi|4505619 paired box 7 isoform 1 [Homo sapiens] 1057 0.0
gi|207029223 paired box 7 isoform 3 [Homo sapiens] 949 0.0
gi|31563340 paired box 3 isoform PAX3 [Homo sapiens] 747 0.0
gi|31563344 paired box 3 isoform PAX3e [Homo sapiens] 745 0.0
gi|31563342 paired box 3 isoform PAX3d [Homo sapiens] 745 0.0
gi|188219638 paired box 3 isoform PAX3i [Homo sapiens] 738 0.0
gi|31563348 paired box 3 isoform PAX3g [Homo sapiens] 625 e-179
gi|31563346 paired box 3 isoform PAX3h [Homo sapiens] 625 e-179
gi|7524356 paired box 3 isoform PAX3b [Homo sapiens] 348 5e-96
gi|6654638 paired box 3 isoform PAX3a [Homo sapiens] 348 7e-96
gi|189083681 paired box gene 6 isoform a [Homo sapiens] 262 6e-70
gi|4505615 paired box gene 6 isoform a [Homo sapiens] 262 6e-70
gi|4580424 paired box gene 6 isoform b [Homo sapiens] 252 5e-67
gi|9951920 paired box 5 [Homo sapiens] 224 2e-58
gi|34878716 paired box protein 2 isoform d [Homo sapiens] 218 8e-57
gi|34878701 paired box protein 2 isoform b [Homo sapiens] 218 8e-57
gi|34878709 paired box protein 2 isoform c [Homo sapiens] 218 1e-56
gi|7524361 paired box 8 isoform PAX8B [Homo sapiens] 211 1e-54
gi|34878699 paired box protein 2 isoform a [Homo sapiens] 209 5e-54
gi|34878703 paired box protein 2 isoform e [Homo sapiens] 209 5e-54
gi|7524363 paired box 8 isoform PAX8C [Homo sapiens] 206 3e-53
gi|7524365 paired box 8 isoform PAX8D [Homo sapiens] 205 7e-53
gi|7669542 paired box 8 isoform PAX8E [Homo sapiens] 205 7e-53
gi|5803117 paired box 8 isoform PAX8A [Homo sapiens] 205 7e-53
gi|197276661 paired box 1 [Homo sapiens] 193 4e-49
gi|7242167 paired box 9 [Homo sapiens] 191 1e-48
gi|170784824 paired box 4 [Homo sapiens] 191 1e-48
gi|24497589 aristaless related homeobox [Homo sapiens] 114 2e-25
gi|113204604 aristaless-like homeobox 3 [Homo sapiens] 112 8e-25
>gi|7524359 paired box 7 isoform 2 [Homo sapiens]
Length = 518
Score = 1062 bits (2746), Expect = 0.0
Identities = 518/518 (100%), Positives = 518/518 (100%)
Query: 1 MAALPGTVPRMMRPAPGQNYPRTGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV 60
MAALPGTVPRMMRPAPGQNYPRTGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV
Sbjct: 1 MAALPGTVPRMMRPAPGQNYPRTGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV 60
Query: 61 EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPRQVATPDVEKKIEE 120
EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPRQVATPDVEKKIEE
Sbjct: 61 EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPRQVATPDVEKKIEE 120
Query: 121 YKRENPGMFSWEIRDRLLKDGHCDRSTVPSVSSISRVLRIKFGKKEEEDEADKKEDDGEK 180
YKRENPGMFSWEIRDRLLKDGHCDRSTVPSVSSISRVLRIKFGKKEEEDEADKKEDDGEK
Sbjct: 121 YKRENPGMFSWEIRDRLLKDGHCDRSTVPSVSSISRVLRIKFGKKEEEDEADKKEDDGEK 180
Query: 181 KAKHSIDGILGDKGNRLDEGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTHYP 240
KAKHSIDGILGDKGNRLDEGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTHYP
Sbjct: 181 KAKHSIDGILGDKGNRLDEGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTHYP 240
Query: 241 DIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPTGMPTLPP 300
DIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPTGMPTLPP
Sbjct: 241 DIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPTGMPTLPP 300
Query: 301 YQLPDSTYPTTTISQDGGSTVHRPQPLPPSTMHQGGLAAAAAAADTSSAYGARHSFSSYS 360
YQLPDSTYPTTTISQDGGSTVHRPQPLPPSTMHQGGLAAAAAAADTSSAYGARHSFSSYS
Sbjct: 301 YQLPDSTYPTTTISQDGGSTVHRPQPLPPSTMHQGGLAAAAAAADTSSAYGARHSFSSYS 360
Query: 361 DSFMNPAAPSNHMNPVSNGLSPQVMSILGNPSAVPPQPQADFSISPLHGGLDSATSISAS 420
DSFMNPAAPSNHMNPVSNGLSPQVMSILGNPSAVPPQPQADFSISPLHGGLDSATSISAS
Sbjct: 361 DSFMNPAAPSNHMNPVSNGLSPQVMSILGNPSAVPPQPQADFSISPLHGGLDSATSISAS 420
Query: 421 CSQRADSIKPGDSLPTSQAYCPPTYSTTGYSVDPVAGYQYGQYGQSECLVPWASPVPIPS 480
CSQRADSIKPGDSLPTSQAYCPPTYSTTGYSVDPVAGYQYGQYGQSECLVPWASPVPIPS
Sbjct: 421 CSQRADSIKPGDSLPTSQAYCPPTYSTTGYSVDPVAGYQYGQYGQSECLVPWASPVPIPS 480
Query: 481 PTPRASCLFMESYKVVSGWGMSISQMEKLKSSQMEQFT 518
PTPRASCLFMESYKVVSGWGMSISQMEKLKSSQMEQFT
Sbjct: 481 PTPRASCLFMESYKVVSGWGMSISQMEKLKSSQMEQFT 518
>gi|4505619 paired box 7 isoform 1 [Homo sapiens]
Length = 520
Score = 1057 bits (2733), Expect = 0.0
Identities = 518/520 (99%), Positives = 518/520 (99%), Gaps = 2/520 (0%)
Query: 1 MAALPGTVPRMMRPAPGQNYPRTGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV 60
MAALPGTVPRMMRPAPGQNYPRTGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV
Sbjct: 1 MAALPGTVPRMMRPAPGQNYPRTGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV 60
Query: 61 EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPRQVATPDVEKKIEE 120
EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPRQVATPDVEKKIEE
Sbjct: 61 EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPRQVATPDVEKKIEE 120
Query: 121 YKRENPGMFSWEIRDRLLKDGHCDRSTVPS--VSSISRVLRIKFGKKEEEDEADKKEDDG 178
YKRENPGMFSWEIRDRLLKDGHCDRSTVPS VSSISRVLRIKFGKKEEEDEADKKEDDG
Sbjct: 121 YKRENPGMFSWEIRDRLLKDGHCDRSTVPSGLVSSISRVLRIKFGKKEEEDEADKKEDDG 180
Query: 179 EKKAKHSIDGILGDKGNRLDEGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTH 238
EKKAKHSIDGILGDKGNRLDEGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTH
Sbjct: 181 EKKAKHSIDGILGDKGNRLDEGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTH 240
Query: 239 YPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPTGMPTL 298
YPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPTGMPTL
Sbjct: 241 YPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPTGMPTL 300
Query: 299 PPYQLPDSTYPTTTISQDGGSTVHRPQPLPPSTMHQGGLAAAAAAADTSSAYGARHSFSS 358
PPYQLPDSTYPTTTISQDGGSTVHRPQPLPPSTMHQGGLAAAAAAADTSSAYGARHSFSS
Sbjct: 301 PPYQLPDSTYPTTTISQDGGSTVHRPQPLPPSTMHQGGLAAAAAAADTSSAYGARHSFSS 360
Query: 359 YSDSFMNPAAPSNHMNPVSNGLSPQVMSILGNPSAVPPQPQADFSISPLHGGLDSATSIS 418
YSDSFMNPAAPSNHMNPVSNGLSPQVMSILGNPSAVPPQPQADFSISPLHGGLDSATSIS
Sbjct: 361 YSDSFMNPAAPSNHMNPVSNGLSPQVMSILGNPSAVPPQPQADFSISPLHGGLDSATSIS 420
Query: 419 ASCSQRADSIKPGDSLPTSQAYCPPTYSTTGYSVDPVAGYQYGQYGQSECLVPWASPVPI 478
ASCSQRADSIKPGDSLPTSQAYCPPTYSTTGYSVDPVAGYQYGQYGQSECLVPWASPVPI
Sbjct: 421 ASCSQRADSIKPGDSLPTSQAYCPPTYSTTGYSVDPVAGYQYGQYGQSECLVPWASPVPI 480
Query: 479 PSPTPRASCLFMESYKVVSGWGMSISQMEKLKSSQMEQFT 518
PSPTPRASCLFMESYKVVSGWGMSISQMEKLKSSQMEQFT
Sbjct: 481 PSPTPRASCLFMESYKVVSGWGMSISQMEKLKSSQMEQFT 520
>gi|207029223 paired box 7 isoform 3 [Homo sapiens]
Length = 505
Score = 949 bits (2452), Expect = 0.0
Identities = 465/468 (99%), Positives = 466/468 (99%), Gaps = 2/468 (0%)
Query: 1 MAALPGTVPRMMRPAPGQNYPRTGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV 60
MAALPGTVPRMMRPAPGQNYPRTGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV
Sbjct: 1 MAALPGTVPRMMRPAPGQNYPRTGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV 60
Query: 61 EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPRQVATPDVEKKIEE 120
EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPRQVATPDVEKKIEE
Sbjct: 61 EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPRQVATPDVEKKIEE 120
Query: 121 YKRENPGMFSWEIRDRLLKDGHCDRSTVPS--VSSISRVLRIKFGKKEEEDEADKKEDDG 178
YKRENPGMFSWEIRDRLLKDGHCDRSTVPS VSSISRVLRIKFGKKEEEDEADKKEDDG
Sbjct: 121 YKRENPGMFSWEIRDRLLKDGHCDRSTVPSGLVSSISRVLRIKFGKKEEEDEADKKEDDG 180
Query: 179 EKKAKHSIDGILGDKGNRLDEGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTH 238
EKKAKHSIDGILGDKGNRLDEGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTH
Sbjct: 181 EKKAKHSIDGILGDKGNRLDEGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTH 240
Query: 239 YPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPTGMPTL 298
YPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPTGMPTL
Sbjct: 241 YPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPTGMPTL 300
Query: 299 PPYQLPDSTYPTTTISQDGGSTVHRPQPLPPSTMHQGGLAAAAAAADTSSAYGARHSFSS 358
PPYQLPDSTYPTTTISQDGGSTVHRPQPLPPSTMHQGGLAAAAAAADTSSAYGARHSFSS
Sbjct: 301 PPYQLPDSTYPTTTISQDGGSTVHRPQPLPPSTMHQGGLAAAAAAADTSSAYGARHSFSS 360
Query: 359 YSDSFMNPAAPSNHMNPVSNGLSPQVMSILGNPSAVPPQPQADFSISPLHGGLDSATSIS 418
YSDSFMNPAAPSNHMNPVSNGLSPQVMSILGNPSAVPPQPQADFSISPLHGGLDSATSIS
Sbjct: 361 YSDSFMNPAAPSNHMNPVSNGLSPQVMSILGNPSAVPPQPQADFSISPLHGGLDSATSIS 420
Query: 419 ASCSQRADSIKPGDSLPTSQAYCPPTYSTTGYSVDPVAGYQYGQYGQS 466
ASCSQRADSIKPGDSLPTSQAYCPPTYSTTGYSVDPVAGYQYGQYGQ+
Sbjct: 421 ASCSQRADSIKPGDSLPTSQAYCPPTYSTTGYSVDPVAGYQYGQYGQT 468
>gi|31563340 paired box 3 isoform PAX3 [Homo sapiens]
Length = 479
Score = 747 bits (1928), Expect = 0.0
Identities = 374/484 (77%), Positives = 413/484 (85%), Gaps = 19/484 (3%)
Query: 1 MAALPGTVPRMMRPAPGQNYPRTGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV 60
M L G VPRMMRP PGQNYPR+GFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV
Sbjct: 1 MTTLAGAVPRMMRPGPGQNYPRSGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV 60
Query: 61 EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPRQVATPDVEKKIEE 120
EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKP+QV TPDVEKKIEE
Sbjct: 61 EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPKQVTTPDVEKKIEE 120
Query: 121 YKRENPGMFSWEIRDRLLKDGHCDRSTVPSVSSISRVLRIKFGKKEEEDEAD---KKEDD 177
YKRENPGMFSWEIRD+LLKD CDR+TVPSVSSISR+LR KFGK EEE EAD K+ ++
Sbjct: 121 YKRENPGMFSWEIRDKLLKDAVCDRNTVPSVSSISRILRSKFGKGEEE-EADLERKEAEE 179
Query: 178 GEKKAKHSIDGILGDKGN--RLDEGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKAFE 235
EKKAKHSIDGIL ++ + + DEGSD++SEPDLPLKRKQRRSRTTFTAEQLEELE+AFE
Sbjct: 180 SEKKAKHSIDGILSERASAPQSDEGSDIDSEPDLPLKRKQRRSRTTFTAEQLEELERAFE 239
Query: 236 RTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPTGM 295
RTHYPDIYTREELAQR KLTEARVQVWFSNRRARWRKQAGANQL AFNHL+PGGFPPT M
Sbjct: 240 RTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAGANQLMAFNHLIPGGFPPTAM 299
Query: 296 PTLPPYQLPDSTYPTTTISQ---DGGSTVHRPQPLPPSTMHQGGLAAAAAAADTSSAY-- 350
PTLP YQL +++Y T+I Q D STVHRPQPLPPST+HQ + + D+SSAY
Sbjct: 300 PTLPTYQLSETSYQPTSIPQAVSDPSSTVHRPQPLPPSTVHQ---STIPSNPDSSSAYCL 356
Query: 351 -GARHSFSSYSDSFMNPAAPSNHMNP-VSNGLSPQVMSILGNPSAVPPQPQADFSISPLH 408
RH FSSY+DSF+ P+ PSN MNP + NGLSPQVM +L N VP QPQ D+++SPL
Sbjct: 357 PSTRHGFSSYTDSFVPPSGPSNPMNPTIGNGLSPQVMGLLTNHGGVPHQPQTDYALSPLT 416
Query: 409 GGLDSATSISASCSQRADSIKPGDSLPTSQAYCPPTYSTTGYSVDPVAGYQYGQYGQSEC 468
GGL+ T++SASCSQR D +K DSLPTSQ+YCPPTYSTTGYS+DPV GYQYGQYGQS+
Sbjct: 417 GGLEPTTTVSASCSQRLDHMKSLDSLPTSQSYCPPTYSTTGYSMDPVTGYQYGQYGQSK- 475
Query: 469 LVPW 472
PW
Sbjct: 476 --PW 477
>gi|31563344 paired box 3 isoform PAX3e [Homo sapiens]
Length = 505
Score = 745 bits (1923), Expect = 0.0
Identities = 372/478 (77%), Positives = 410/478 (85%), Gaps = 16/478 (3%)
Query: 1 MAALPGTVPRMMRPAPGQNYPRTGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV 60
M L G VPRMMRP PGQNYPR+GFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV
Sbjct: 1 MTTLAGAVPRMMRPGPGQNYPRSGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV 60
Query: 61 EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPRQVATPDVEKKIEE 120
EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKP+QV TPDVEKKIEE
Sbjct: 61 EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPKQVTTPDVEKKIEE 120
Query: 121 YKRENPGMFSWEIRDRLLKDGHCDRSTVPSVSSISRVLRIKFGKKEEEDEAD---KKEDD 177
YKRENPGMFSWEIRD+LLKD CDR+TVPSVSSISR+LR KFGK EEE EAD K+ ++
Sbjct: 121 YKRENPGMFSWEIRDKLLKDAVCDRNTVPSVSSISRILRSKFGKGEEE-EADLERKEAEE 179
Query: 178 GEKKAKHSIDGILGDKGN--RLDEGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKAFE 235
EKKAKHSIDGIL ++ + + DEGSD++SEPDLPLKRKQRRSRTTFTAEQLEELE+AFE
Sbjct: 180 SEKKAKHSIDGILSERASAPQSDEGSDIDSEPDLPLKRKQRRSRTTFTAEQLEELERAFE 239
Query: 236 RTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPTGM 295
RTHYPDIYTREELAQR KLTEARVQVWFSNRRARWRKQAGANQL AFNHL+PGGFPPT M
Sbjct: 240 RTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAGANQLMAFNHLIPGGFPPTAM 299
Query: 296 PTLPPYQLPDSTYPTTTISQ---DGGSTVHRPQPLPPSTMHQGGLAAAAAAADTSSAY-- 350
PTLP YQL +++Y T+I Q D STVHRPQPLPPST+HQ + + D+SSAY
Sbjct: 300 PTLPTYQLSETSYQPTSIPQAVSDPSSTVHRPQPLPPSTVHQ---STIPSNPDSSSAYCL 356
Query: 351 -GARHSFSSYSDSFMNPAAPSNHMNP-VSNGLSPQVMSILGNPSAVPPQPQADFSISPLH 408
RH FSSY+DSF+ P+ PSN MNP + NGLSPQVM +L N VP QPQ D+++SPL
Sbjct: 357 PSTRHGFSSYTDSFVPPSGPSNPMNPTIGNGLSPQVMGLLTNHGGVPHQPQTDYALSPLT 416
Query: 409 GGLDSATSISASCSQRADSIKPGDSLPTSQAYCPPTYSTTGYSVDPVAGYQYGQYGQS 466
GGL+ T++SASCSQR D +K DSLPTSQ+YCPPTYSTTGYS+DPV GYQYGQYGQS
Sbjct: 417 GGLEPTTTVSASCSQRLDHMKSLDSLPTSQSYCPPTYSTTGYSMDPVTGYQYGQYGQS 474
>gi|31563342 paired box 3 isoform PAX3d [Homo sapiens]
Length = 484
Score = 745 bits (1923), Expect = 0.0
Identities = 372/478 (77%), Positives = 410/478 (85%), Gaps = 16/478 (3%)
Query: 1 MAALPGTVPRMMRPAPGQNYPRTGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV 60
M L G VPRMMRP PGQNYPR+GFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV
Sbjct: 1 MTTLAGAVPRMMRPGPGQNYPRSGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV 60
Query: 61 EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPRQVATPDVEKKIEE 120
EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKP+QV TPDVEKKIEE
Sbjct: 61 EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPKQVTTPDVEKKIEE 120
Query: 121 YKRENPGMFSWEIRDRLLKDGHCDRSTVPSVSSISRVLRIKFGKKEEEDEAD---KKEDD 177
YKRENPGMFSWEIRD+LLKD CDR+TVPSVSSISR+LR KFGK EEE EAD K+ ++
Sbjct: 121 YKRENPGMFSWEIRDKLLKDAVCDRNTVPSVSSISRILRSKFGKGEEE-EADLERKEAEE 179
Query: 178 GEKKAKHSIDGILGDKGN--RLDEGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKAFE 235
EKKAKHSIDGIL ++ + + DEGSD++SEPDLPLKRKQRRSRTTFTAEQLEELE+AFE
Sbjct: 180 SEKKAKHSIDGILSERASAPQSDEGSDIDSEPDLPLKRKQRRSRTTFTAEQLEELERAFE 239
Query: 236 RTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPTGM 295
RTHYPDIYTREELAQR KLTEARVQVWFSNRRARWRKQAGANQL AFNHL+PGGFPPT M
Sbjct: 240 RTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAGANQLMAFNHLIPGGFPPTAM 299
Query: 296 PTLPPYQLPDSTYPTTTISQ---DGGSTVHRPQPLPPSTMHQGGLAAAAAAADTSSAY-- 350
PTLP YQL +++Y T+I Q D STVHRPQPLPPST+HQ + + D+SSAY
Sbjct: 300 PTLPTYQLSETSYQPTSIPQAVSDPSSTVHRPQPLPPSTVHQ---STIPSNPDSSSAYCL 356
Query: 351 -GARHSFSSYSDSFMNPAAPSNHMNP-VSNGLSPQVMSILGNPSAVPPQPQADFSISPLH 408
RH FSSY+DSF+ P+ PSN MNP + NGLSPQVM +L N VP QPQ D+++SPL
Sbjct: 357 PSTRHGFSSYTDSFVPPSGPSNPMNPTIGNGLSPQVMGLLTNHGGVPHQPQTDYALSPLT 416
Query: 409 GGLDSATSISASCSQRADSIKPGDSLPTSQAYCPPTYSTTGYSVDPVAGYQYGQYGQS 466
GGL+ T++SASCSQR D +K DSLPTSQ+YCPPTYSTTGYS+DPV GYQYGQYGQS
Sbjct: 417 GGLEPTTTVSASCSQRLDHMKSLDSLPTSQSYCPPTYSTTGYSMDPVTGYQYGQYGQS 474
>gi|188219638 paired box 3 isoform PAX3i [Homo sapiens]
Length = 483
Score = 738 bits (1906), Expect = 0.0
Identities = 371/478 (77%), Positives = 409/478 (85%), Gaps = 17/478 (3%)
Query: 1 MAALPGTVPRMMRPAPGQNYPRTGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV 60
M L G VPRMMRP PGQNYPR+GFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV
Sbjct: 1 MTTLAGAVPRMMRPGPGQNYPRSGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV 60
Query: 61 EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPRQVATPDVEKKIEE 120
EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKP+ V TPDVEKKIEE
Sbjct: 61 EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPK-VTTPDVEKKIEE 119
Query: 121 YKRENPGMFSWEIRDRLLKDGHCDRSTVPSVSSISRVLRIKFGKKEEEDEAD---KKEDD 177
YKRENPGMFSWEIRD+LLKD CDR+TVPSVSSISR+LR KFGK EEE EAD K+ ++
Sbjct: 120 YKRENPGMFSWEIRDKLLKDAVCDRNTVPSVSSISRILRSKFGKGEEE-EADLERKEAEE 178
Query: 178 GEKKAKHSIDGILGDKGN--RLDEGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKAFE 235
EKKAKHSIDGIL ++ + + DEGSD++SEPDLPLKRKQRRSRTTFTAEQLEELE+AFE
Sbjct: 179 SEKKAKHSIDGILSERASAPQSDEGSDIDSEPDLPLKRKQRRSRTTFTAEQLEELERAFE 238
Query: 236 RTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPTGM 295
RTHYPDIYTREELAQR KLTEARVQVWFSNRRARWRKQAGANQL AFNHL+PGGFPPT M
Sbjct: 239 RTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAGANQLMAFNHLIPGGFPPTAM 298
Query: 296 PTLPPYQLPDSTYPTTTISQ---DGGSTVHRPQPLPPSTMHQGGLAAAAAAADTSSAY-- 350
PTLP YQL +++Y T+I Q D STVHRPQPLPPST+HQ + + D+SSAY
Sbjct: 299 PTLPTYQLSETSYQPTSIPQAVSDPSSTVHRPQPLPPSTVHQ---STIPSNPDSSSAYCL 355
Query: 351 -GARHSFSSYSDSFMNPAAPSNHMNP-VSNGLSPQVMSILGNPSAVPPQPQADFSISPLH 408
RH FSSY+DSF+ P+ PSN MNP + NGLSPQVM +L N VP QPQ D+++SPL
Sbjct: 356 PSTRHGFSSYTDSFVPPSGPSNPMNPTIGNGLSPQVMGLLTNHGGVPHQPQTDYALSPLT 415
Query: 409 GGLDSATSISASCSQRADSIKPGDSLPTSQAYCPPTYSTTGYSVDPVAGYQYGQYGQS 466
GGL+ T++SASCSQR D +K DSLPTSQ+YCPPTYSTTGYS+DPV GYQYGQYGQS
Sbjct: 416 GGLEPTTTVSASCSQRLDHMKSLDSLPTSQSYCPPTYSTTGYSMDPVTGYQYGQYGQS 473
>gi|31563348 paired box 3 isoform PAX3g [Homo sapiens]
Length = 403
Score = 625 bits (1611), Expect = e-179
Identities = 316/402 (78%), Positives = 346/402 (86%), Gaps = 16/402 (3%)
Query: 1 MAALPGTVPRMMRPAPGQNYPRTGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV 60
M L G VPRMMRP PGQNYPR+GFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV
Sbjct: 1 MTTLAGAVPRMMRPGPGQNYPRSGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV 60
Query: 61 EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPRQVATPDVEKKIEE 120
EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKP+QV TPDVEKKIEE
Sbjct: 61 EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPKQVTTPDVEKKIEE 120
Query: 121 YKRENPGMFSWEIRDRLLKDGHCDRSTVPSVSSISRVLRIKFGKKEEEDEAD---KKEDD 177
YKRENPGMFSWEIRD+LLKD CDR+TVPSVSSISR+LR KFGK EEE EAD K+ ++
Sbjct: 121 YKRENPGMFSWEIRDKLLKDAVCDRNTVPSVSSISRILRSKFGKGEEE-EADLERKEAEE 179
Query: 178 GEKKAKHSIDGILGDKGN--RLDEGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKAFE 235
EKKAKHSIDGIL ++ + + DEGSD++SEPDLPLKRKQRRSRTTFTAEQLEELE+AFE
Sbjct: 180 SEKKAKHSIDGILSERASAPQSDEGSDIDSEPDLPLKRKQRRSRTTFTAEQLEELERAFE 239
Query: 236 RTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPTGM 295
RTHYPDIYTREELAQR KLTEARVQVWFSNRRARWRKQAGANQL AFNHL+PGGFPPT M
Sbjct: 240 RTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAGANQLMAFNHLIPGGFPPTAM 299
Query: 296 PTLPPYQLPDSTYPTTTISQ---DGGSTVHRPQPLPPSTMHQGGLAAAAAAADTSSAY-- 350
PTLP YQL +++Y T+I Q D STVHRPQPLPPST+HQ + + D+SSAY
Sbjct: 300 PTLPTYQLSETSYQPTSIPQAVSDPSSTVHRPQPLPPSTVHQ---STIPSNPDSSSAYCL 356
Query: 351 -GARHSFSSYSDSFMNPAAPSNHMNP-VSNGLSPQVMSILGN 390
RH FSSY+DSF+ P+ PSN MNP + NGLSPQV I+ +
Sbjct: 357 PSTRHGFSSYTDSFVPPSGPSNPMNPTIGNGLSPQVPFIISS 398
>gi|31563346 paired box 3 isoform PAX3h [Homo sapiens]
Length = 407
Score = 625 bits (1611), Expect = e-179
Identities = 316/402 (78%), Positives = 346/402 (86%), Gaps = 16/402 (3%)
Query: 1 MAALPGTVPRMMRPAPGQNYPRTGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV 60
M L G VPRMMRP PGQNYPR+GFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV
Sbjct: 1 MTTLAGAVPRMMRPGPGQNYPRSGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV 60
Query: 61 EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPRQVATPDVEKKIEE 120
EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKP+QV TPDVEKKIEE
Sbjct: 61 EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPKQVTTPDVEKKIEE 120
Query: 121 YKRENPGMFSWEIRDRLLKDGHCDRSTVPSVSSISRVLRIKFGKKEEEDEAD---KKEDD 177
YKRENPGMFSWEIRD+LLKD CDR+TVPSVSSISR+LR KFGK EEE EAD K+ ++
Sbjct: 121 YKRENPGMFSWEIRDKLLKDAVCDRNTVPSVSSISRILRSKFGKGEEE-EADLERKEAEE 179
Query: 178 GEKKAKHSIDGILGDKGN--RLDEGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKAFE 235
EKKAKHSIDGIL ++ + + DEGSD++SEPDLPLKRKQRRSRTTFTAEQLEELE+AFE
Sbjct: 180 SEKKAKHSIDGILSERASAPQSDEGSDIDSEPDLPLKRKQRRSRTTFTAEQLEELERAFE 239
Query: 236 RTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPTGM 295
RTHYPDIYTREELAQR KLTEARVQVWFSNRRARWRKQAGANQL AFNHL+PGGFPPT M
Sbjct: 240 RTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAGANQLMAFNHLIPGGFPPTAM 299
Query: 296 PTLPPYQLPDSTYPTTTISQ---DGGSTVHRPQPLPPSTMHQGGLAAAAAAADTSSAY-- 350
PTLP YQL +++Y T+I Q D STVHRPQPLPPST+HQ + + D+SSAY
Sbjct: 300 PTLPTYQLSETSYQPTSIPQAVSDPSSTVHRPQPLPPSTVHQ---STIPSNPDSSSAYCL 356
Query: 351 -GARHSFSSYSDSFMNPAAPSNHMNP-VSNGLSPQVMSILGN 390
RH FSSY+DSF+ P+ PSN MNP + NGLSPQV I+ +
Sbjct: 357 PSTRHGFSSYTDSFVPPSGPSNPMNPTIGNGLSPQVPFIISS 398
>gi|7524356 paired box 3 isoform PAX3b [Homo sapiens]
Length = 206
Score = 348 bits (894), Expect = 5e-96
Identities = 172/203 (84%), Positives = 182/203 (89%), Gaps = 4/203 (1%)
Query: 1 MAALPGTVPRMMRPAPGQNYPRTGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV 60
M L G VPRMMRP PGQNYPR+GFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV
Sbjct: 1 MTTLAGAVPRMMRPGPGQNYPRSGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV 60
Query: 61 EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPRQVATPDVEKKIEE 120
EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKP+QV TPDVEKKIEE
Sbjct: 61 EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPKQVTTPDVEKKIEE 120
Query: 121 YKRENPGMFSWEIRDRLLKDGHCDRSTVPSVSSISRVLRIKFGKKEEEDEAD---KKEDD 177
YKRENPGMFSWEIRD+LLKD CDR+TVPSVSSISR+LR KFGK EEE EAD K+ ++
Sbjct: 121 YKRENPGMFSWEIRDKLLKDAVCDRNTVPSVSSISRILRSKFGKGEEE-EADLERKEAEE 179
Query: 178 GEKKAKHSIDGILGDKGNRLDEG 200
EKKAKHSIDGIL ++G L G
Sbjct: 180 SEKKAKHSIDGILSERGKALVSG 202
>gi|6654638 paired box 3 isoform PAX3a [Homo sapiens]
Length = 215
Score = 348 bits (893), Expect = 7e-96
Identities = 171/199 (85%), Positives = 181/199 (90%), Gaps = 4/199 (2%)
Query: 1 MAALPGTVPRMMRPAPGQNYPRTGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV 60
M L G VPRMMRP PGQNYPR+GFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV
Sbjct: 1 MTTLAGAVPRMMRPGPGQNYPRSGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV 60
Query: 61 EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPRQVATPDVEKKIEE 120
EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKP+QV TPDVEKKIEE
Sbjct: 61 EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPKQVTTPDVEKKIEE 120
Query: 121 YKRENPGMFSWEIRDRLLKDGHCDRSTVPSVSSISRVLRIKFGKKEEEDEAD---KKEDD 177
YKRENPGMFSWEIRD+LLKD CDR+TVPSVSSISR+LR KFGK EEE EAD K+ ++
Sbjct: 121 YKRENPGMFSWEIRDKLLKDAVCDRNTVPSVSSISRILRSKFGKGEEE-EADLERKEAEE 179
Query: 178 GEKKAKHSIDGILGDKGNR 196
EKKAKHSIDGIL ++G R
Sbjct: 180 SEKKAKHSIDGILSERGKR 198
>gi|189083681 paired box gene 6 isoform a [Homo sapiens]
Length = 422
Score = 262 bits (669), Expect = 6e-70
Identities = 179/449 (39%), Positives = 230/449 (51%), Gaps = 81/449 (18%)
Query: 38 VNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIR 97
VNQLGGVF+NGRPLP+ R KIVE+AH G RPC ISR L+VS+GCVSKIL RY ETGSIR
Sbjct: 8 VNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRYYETGSIR 67
Query: 98 PGAIGGSKPRQVATPDVEKKIEEYKRENPGMFSWEIRDRLLKDGHCDRSTVPSVSSISRV 157
P AIGGSKPR VATP+V KI +YKRE P +F+WEIRDRLL +G C +PSVSSI+RV
Sbjct: 68 PRAIGGSKPR-VATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGVCTNDNIPSVSSINRV 126
Query: 158 LRIKFGKKEE-------------------------------------EDEADKKEDDGEK 180
LR +K++ +D ++E GE
Sbjct: 127 LRNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGWYPGTSVPGQPTQDGCQQQEGGGEN 186
Query: 181 KAKHSIDGILGDKGNRLDEGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTHYP 240
S +G E SD E++ L LKRK +R+RT+FT EQ+E LEK FERTHYP
Sbjct: 187 TNSISSNG----------EDSD-EAQMRLQLKRKLQRNRTSFTQEQIEALEKEFERTHYP 235
Query: 241 DIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPTGMPTLPP 300
D++ RE LA + L EAR+QVWFSNRRA+WR++ P P + +
Sbjct: 236 DVFARERLAAKIDLPEARIQVWFSNRRAKWRREEKLRNQRRQASNTPSHIPISSSFSTSV 295
Query: 301 YQ-LPDSTYPTTTISQDGGSTVHRPQPLPPSTMHQGGLAAAAAAADTSSAYGARHSFSSY 359
YQ +P T P ++ + GS + R A +T SA SF+
Sbjct: 296 YQPIPQPTTPVSSFT--SGSMLGRTD---------------TALTNTYSALPPMPSFTMA 338
Query: 360 SDSFMNPAAPSNHMNPVSNGLSPQVMSILGN--PSAVPPQPQADFSISPLHGGLDSATSI 417
++ M P PS + + + P S+ G + PP Q + P+ G TS
Sbjct: 339 NNLPMQPPVPSQTSS--YSCMLPTSPSVNGRSYDTYTPPHMQTHMNSQPM--GTSGTTST 394
Query: 418 SASCSQRADSIKPGDSLPTSQAYCPPTYS 446
I PG S+P P S
Sbjct: 395 GL--------ISPGVSVPVQVPGSEPDMS 415
>gi|4505615 paired box gene 6 isoform a [Homo sapiens]
Length = 422
Score = 262 bits (669), Expect = 6e-70
Identities = 179/449 (39%), Positives = 230/449 (51%), Gaps = 81/449 (18%)
Query: 38 VNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIR 97
VNQLGGVF+NGRPLP+ R KIVE+AH G RPC ISR L+VS+GCVSKIL RY ETGSIR
Sbjct: 8 VNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRYYETGSIR 67
Query: 98 PGAIGGSKPRQVATPDVEKKIEEYKRENPGMFSWEIRDRLLKDGHCDRSTVPSVSSISRV 157
P AIGGSKPR VATP+V KI +YKRE P +F+WEIRDRLL +G C +PSVSSI+RV
Sbjct: 68 PRAIGGSKPR-VATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGVCTNDNIPSVSSINRV 126
Query: 158 LRIKFGKKEE-------------------------------------EDEADKKEDDGEK 180
LR +K++ +D ++E GE
Sbjct: 127 LRNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGWYPGTSVPGQPTQDGCQQQEGGGEN 186
Query: 181 KAKHSIDGILGDKGNRLDEGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTHYP 240
S +G E SD E++ L LKRK +R+RT+FT EQ+E LEK FERTHYP
Sbjct: 187 TNSISSNG----------EDSD-EAQMRLQLKRKLQRNRTSFTQEQIEALEKEFERTHYP 235
Query: 241 DIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPTGMPTLPP 300
D++ RE LA + L EAR+QVWFSNRRA+WR++ P P + +
Sbjct: 236 DVFARERLAAKIDLPEARIQVWFSNRRAKWRREEKLRNQRRQASNTPSHIPISSSFSTSV 295
Query: 301 YQ-LPDSTYPTTTISQDGGSTVHRPQPLPPSTMHQGGLAAAAAAADTSSAYGARHSFSSY 359
YQ +P T P ++ + GS + R A +T SA SF+
Sbjct: 296 YQPIPQPTTPVSSFT--SGSMLGRTD---------------TALTNTYSALPPMPSFTMA 338
Query: 360 SDSFMNPAAPSNHMNPVSNGLSPQVMSILGN--PSAVPPQPQADFSISPLHGGLDSATSI 417
++ M P PS + + + P S+ G + PP Q + P+ G TS
Sbjct: 339 NNLPMQPPVPSQTSS--YSCMLPTSPSVNGRSYDTYTPPHMQTHMNSQPM--GTSGTTST 394
Query: 418 SASCSQRADSIKPGDSLPTSQAYCPPTYS 446
I PG S+P P S
Sbjct: 395 GL--------ISPGVSVPVQVPGSEPDMS 415
>gi|4580424 paired box gene 6 isoform b [Homo sapiens]
Length = 436
Score = 252 bits (644), Expect = 5e-67
Identities = 179/463 (38%), Positives = 230/463 (49%), Gaps = 95/463 (20%)
Query: 38 VNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLR--------------VSHGCV 83
VNQLGGVF+NGRPLP+ R KIVE+AH G RPC ISR L+ VS+GCV
Sbjct: 8 VNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQTHADAKVQVLDNQNVSNGCV 67
Query: 84 SKILCRYQETGSIRPGAIGGSKPRQVATPDVEKKIEEYKRENPGMFSWEIRDRLLKDGHC 143
SKIL RY ETGSIRP AIGGSKPR VATP+V KI +YKRE P +F+WEIRDRLL +G C
Sbjct: 68 SKILGRYYETGSIRPRAIGGSKPR-VATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGVC 126
Query: 144 DRSTVPSVSSISRVLRIKFGKKEE------------------------------------ 167
+PSVSSI+RVLR +K++
Sbjct: 127 TNDNIPSVSSINRVLRNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGWYPGTSVPGQP 186
Query: 168 -EDEADKKEDDGEKKAKHSIDGILGDKGNRLDEGSDVESEPDLPLKRKQRRSRTTFTAEQ 226
+D ++E GE S +G E SD E++ L LKRK +R+RT+FT EQ
Sbjct: 187 TQDGCQQQEGGGENTNSISSNG----------EDSD-EAQMRLQLKRKLQRNRTSFTQEQ 235
Query: 227 LEELEKAFERTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLL 286
+E LEK FERTHYPD++ RE LA + L EAR+QVWFSNRRA+WR++
Sbjct: 236 IEALEKEFERTHYPDVFARERLAAKIDLPEARIQVWFSNRRAKWRREEKLRNQRRQASNT 295
Query: 287 PGGFPPTGMPTLPPYQ-LPDSTYPTTTISQDGGSTVHRPQPLPPSTMHQGGLAAAAAAAD 345
P P + + YQ +P T P ++ + GS + R A +
Sbjct: 296 PSHIPISSSFSTSVYQPIPQPTTPVSSFT--SGSMLGRTD---------------TALTN 338
Query: 346 TSSAYGARHSFSSYSDSFMNPAAPSNHMNPVSNGLSPQVMSILGN--PSAVPPQPQADFS 403
T SA SF+ ++ M P PS + + + P S+ G + PP Q +
Sbjct: 339 TYSALPPMPSFTMANNLPMQPPVPSQTSS--YSCMLPTSPSVNGRSYDTYTPPHMQTHMN 396
Query: 404 ISPLHGGLDSATSISASCSQRADSIKPGDSLPTSQAYCPPTYS 446
P+ G TS I PG S+P P S
Sbjct: 397 SQPM--GTSGTTSTGL--------ISPGVSVPVQVPGSEPDMS 429
>gi|9951920 paired box 5 [Homo sapiens]
Length = 391
Score = 224 bits (570), Expect = 2e-58
Identities = 148/369 (40%), Positives = 192/369 (52%), Gaps = 41/369 (11%)
Query: 25 FPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVS 84
+P ++ G G VNQLGGVF+NGRPLP+ +R +IVE+AH G+RPC ISRQLRVSHGCVS
Sbjct: 7 YPTPRTSRTGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVS 66
Query: 85 KILCRYQETGSIRPGAIGGSKPRQVATPDVEKKIEEYKRENPGMFSWEIRDRLLKDGHCD 144
KIL RY ETGSI+PG IGGSKP+ VATP V +KI EYKR+NP MF+WEIRDRLL + CD
Sbjct: 67 KILGRYYETGSIKPGVIGGSKPK-VATPKVVEKIAEYKRQNPTMFAWEIRDRLLAERVCD 125
Query: 145 RSTVPSVSSISRVLRIKFGKKEEEDEADKKE--------------DDGEKKAKHSIDGIL 190
TVPSVSSI+R++R K + + + +SI GIL
Sbjct: 126 NDTVPSVSSINRIIRTKVQQPPNQPVPASSHSIVSTGSVTQVSSVSTDSAGSSYSISGIL 185
Query: 191 G-------DKGNRLDEG---SDVESEPDLP---LKRKQRRSRTTFTAEQLEELEKAFERT 237
G + DEG S V + LP RKQ R FT +QLE L++ FER
Sbjct: 186 GITSPSADTNKRKRDEGIQESPVPNGHSLPGRDFLRKQMRG-DLFTQQQLEVLDRVFERQ 244
Query: 238 HYPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPTGMPT 297
HY DI+T E + + TE + + + A +PG P P
Sbjct: 245 HYSDIFTTTEPIKPEQTTEYSAMASLAGGLDDMKANLASPTPADIGSSVPG---PQSYPI 301
Query: 298 LPPYQLPDSTYPTTTISQDGGSTVHRPQPLPPSTMHQGGLAAAAAAADTSSAYGARHSFS 357
+ L +T P G H P P + L ++ S + + +S
Sbjct: 302 VTGRDLASTTLP--------GYPPHVP-PAGQGSYSAPTLTGMVPGSEFSGSPYSHPQYS 352
Query: 358 SYSDSFMNP 366
SY+DS+ P
Sbjct: 353 SYNDSWRFP 361
>gi|34878716 paired box protein 2 isoform d [Homo sapiens]
Length = 408
Score = 218 bits (556), Expect = 8e-57
Identities = 140/340 (41%), Positives = 183/340 (53%), Gaps = 50/340 (14%)
Query: 34 GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQET 93
G G VNQLGGVF+NGRPLP+ +R +IVE+AH G+RPC ISRQLRVSHGCVSKIL RY ET
Sbjct: 16 GHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYET 75
Query: 94 GSIRPGAIGGSKPRQVATPDVEKKIEEYKRENPGMFSWEIRDRLLKDGHCDRSTVPSVSS 153
GSI+PG IGGSKP+ VATP V KI EYKR+NP MF+WEIRDRLL +G CD TVPSVSS
Sbjct: 76 GSIKPGVIGGSKPK-VATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSVSS 134
Query: 154 ISRVLRIKFGKK--------------------EEEDEADKKEDDGEKKAKHSIDGILG-- 191
I+R++R K + + +SI+GILG
Sbjct: 135 INRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASNDPVGSYSINGILGIP 194
Query: 192 -DKGNRLDEGSDV--------ESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTHYPDI 242
G + DV +S+ + RK R+ TFT +QLE L++ FER YPD+
Sbjct: 195 RSNGEKRKRDEDVSEGSVPNGDSQSGVDSLRKHLRA-DTFTQQQLEALDRVFERPSYPDV 253
Query: 243 YTREELAQRTKLTEARVQVWF-------SNRRARWRKQAGANQLAAFNHLLPGG--FPPT 293
+ E + + E + S+ A + G+N + + G T
Sbjct: 254 FQASEHIKSEQGNEYSLPALTPGLDEVKSSLSASTNPELGSNVSGTQTYPVVTGRDMAST 313
Query: 294 GMPTLPPYQLP--DSTYPTTTI------SQDGGSTVHRPQ 325
+P PP+ P +YPT+T+ S+ G+ PQ
Sbjct: 314 TLPGYPPHVPPTGQGSYPTSTLAGMVPGSEFSGNPYSHPQ 353
>gi|34878701 paired box protein 2 isoform b [Homo sapiens]
Length = 393
Score = 218 bits (556), Expect = 8e-57
Identities = 140/340 (41%), Positives = 183/340 (53%), Gaps = 50/340 (14%)
Query: 34 GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQET 93
G G VNQLGGVF+NGRPLP+ +R +IVE+AH G+RPC ISRQLRVSHGCVSKIL RY ET
Sbjct: 16 GHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYET 75
Query: 94 GSIRPGAIGGSKPRQVATPDVEKKIEEYKRENPGMFSWEIRDRLLKDGHCDRSTVPSVSS 153
GSI+PG IGGSKP+ VATP V KI EYKR+NP MF+WEIRDRLL +G CD TVPSVSS
Sbjct: 76 GSIKPGVIGGSKPK-VATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSVSS 134
Query: 154 ISRVLRIKFGKK--------------------EEEDEADKKEDDGEKKAKHSIDGILG-- 191
I+R++R K + + +SI+GILG
Sbjct: 135 INRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASNDPVGSYSINGILGIP 194
Query: 192 -DKGNRLDEGSDV--------ESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTHYPDI 242
G + DV +S+ + RK R+ TFT +QLE L++ FER YPD+
Sbjct: 195 RSNGEKRKRDEDVSEGSVPNGDSQSGVDSLRKHLRA-DTFTQQQLEALDRVFERPSYPDV 253
Query: 243 YTREELAQRTKLTEARVQVWF-------SNRRARWRKQAGANQLAAFNHLLPGG--FPPT 293
+ E + + E + S+ A + G+N + + G T
Sbjct: 254 FQASEHIKSEQGNEYSLPALTPGLDEVKSSLSASTNPELGSNVSGTQTYPVVTGRDMAST 313
Query: 294 GMPTLPPYQLP--DSTYPTTTI------SQDGGSTVHRPQ 325
+P PP+ P +YPT+T+ S+ G+ PQ
Sbjct: 314 TLPGYPPHVPPTGQGSYPTSTLAGMVPGSEFSGNPYSHPQ 353
>gi|34878709 paired box protein 2 isoform c [Homo sapiens]
Length = 396
Score = 218 bits (555), Expect = 1e-56
Identities = 136/323 (42%), Positives = 178/323 (55%), Gaps = 44/323 (13%)
Query: 34 GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQET 93
G G VNQLGGVF+NGRPLP+ +R +IVE+AH G+RPC ISRQLRVSHGCVSKIL RY ET
Sbjct: 16 GHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYET 75
Query: 94 GSIRPGAIGGSKPRQVATPDVEKKIEEYKRENPGMFSWEIRDRLLKDGHCDRSTVPSVSS 153
GSI+PG IGGSKP+ VATP V KI EYKR+NP MF+WEIRDRLL +G CD TVPSVSS
Sbjct: 76 GSIKPGVIGGSKPK-VATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSVSS 134
Query: 154 ISRVLRIKFGKK--------------------EEEDEADKKEDDGEKKAKHSIDGILG-- 191
I+R++R K + + +SI+GILG
Sbjct: 135 INRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASNDPVGSYSINGILGIP 194
Query: 192 -DKGNRLDEGSDV--------ESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTHYPDI 242
G + DV +S+ + RK R+ TFT +QLE L++ FER YPD+
Sbjct: 195 RSNGEKRKRDEDVSEGSVPNGDSQSGVDSLRKHLRA-DTFTQQQLEALDRVFERPSYPDV 253
Query: 243 YTREELAQRTKLTEARVQVWF-------SNRRARWRKQAGANQLAAFNHLLPGG--FPPT 293
+ E + + E + S+ A + G+N + + G T
Sbjct: 254 FQASEHIKSEQGNEYSLPALTPGLDEVKSSLSASTNPELGSNVSGTQTYPVVTGRDMAST 313
Query: 294 GMPTLPPYQLP--DSTYPTTTIS 314
+P PP+ P +YPT+T++
Sbjct: 314 TLPGYPPHVPPTGQGSYPTSTLA 336
>gi|7524361 paired box 8 isoform PAX8B [Homo sapiens]
Length = 387
Score = 211 bits (537), Expect = 1e-54
Identities = 158/408 (38%), Positives = 199/408 (48%), Gaps = 84/408 (20%)
Query: 34 GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQET 93
G G +NQLGG F+NGRPLP +R +IV++AH G+RPC ISRQLRVSHGCVSKIL RY ET
Sbjct: 9 GHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSKILGRYYET 68
Query: 94 GSIRPGAIGGSKPRQVATPDVEKKIEEYKRENPGMFSWEIRDRLLKDGHCDRSTVPSVSS 153
GSIRPG IGGSKP+ VATP V +KI +YKR+NP MF+WEIRDRLL +G CD TVPSVSS
Sbjct: 69 GSIRPGVIGGSKPK-VATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDNDTVPSVSS 127
Query: 154 ISRVLRIK----FGKKEEEDEADKKEDDGEK------------------KAKHSIDGILG 191
I+R++R K F + A K G + +SI+G+LG
Sbjct: 128 INRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTYSINGLLG 187
Query: 192 ------DKGNRLDEGSD-----VESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTHYP 240
DK D D ++S+ RK R+ F+ LE LE FER HYP
Sbjct: 188 IAQPGSDKRKMDDSDQDSCRLSIDSQSSSSGPRKHLRT-DAFSQHHLEPLECPFERQHYP 246
Query: 241 DIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPTGMPTLPP 300
+ Y + + + G L N L G TL P
Sbjct: 247 EAYASP---------------------SHTKGEQGLYPLPLLNSTL-----DDGKATLTP 280
Query: 301 YQLP-------DSTYPTTTISQDGGSTVHRPQPLPPSTMHQGGLAAAAAAA------DTS 347
P TYP + G T+ P P T QG A++A A +
Sbjct: 281 SNTPLGRNLSTHQTYPVVAGREMVGPTLPGYPPHIP-TSGQGSYASSAIAGMVAGSEYSG 339
Query: 348 SAYGARHSFSSYSDSFMNPAAPSNHMNPVSNGLSPQVMSILGNPSAVP 395
+AYG +SSYS+++ P + S SP S PSA P
Sbjct: 340 NAYG-HTPYSSYSEAWRFPNS--------SLLSSPYYYSSTSRPSAPP 378
>gi|34878699 paired box protein 2 isoform a [Homo sapiens]
Length = 416
Score = 209 bits (532), Expect = 5e-54
Identities = 142/363 (39%), Positives = 187/363 (51%), Gaps = 73/363 (20%)
Query: 34 GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQET 93
G G VNQLGGVF+NGRPLP+ +R +IVE+AH G+RPC ISRQLRVSHGCVSKIL RY ET
Sbjct: 16 GHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYET 75
Query: 94 GSIRPGAIGGSKPRQVATPDVEKKIEEYKRENPGMFSWEIRDRLLKDGHCDRSTVPSVSS 153
GSI+PG IGGSKP+ VATP V KI EYKR+NP MF+WEIRDRLL +G CD TVPSVSS
Sbjct: 76 GSIKPGVIGGSKPK-VATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSVSS 134
Query: 154 ISRVLRIKFGKK--------------------EEEDEADKKEDDGEKKAKHSIDGIL--- 190
I+R++R K + + +SI+GIL
Sbjct: 135 INRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASNDPVGSYSINGILGIP 194
Query: 191 ---GDKGNR--------------------------LDEGS--DVESEPDLPLKRKQRRSR 219
G+K R + EGS + +S+ + RK R+
Sbjct: 195 RSNGEKRKRDEVEVYTDPAHIRGGGGLHLVWTLRDVSEGSVPNGDSQSGVDSLRKHLRA- 253
Query: 220 TTFTAEQLEELEKAFERTHYPDIYTREELAQRTKLTEARVQVWF-------SNRRARWRK 272
TFT +QLE L++ FER YPD++ E + + E + S+ A
Sbjct: 254 DTFTQQQLEALDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGLDEVKSSLSASTNP 313
Query: 273 QAGANQLAAFNHLLPGG--FPPTGMPTLPPYQLP--DSTYPTTTI------SQDGGSTVH 322
+ G+N + + G T +P PP+ P +YPT+T+ S+ G+
Sbjct: 314 ELGSNVSGTQTYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAGMVPGSEFSGNPYS 373
Query: 323 RPQ 325
PQ
Sbjct: 374 HPQ 376
>gi|34878703 paired box protein 2 isoform e [Homo sapiens]
Length = 431
Score = 209 bits (532), Expect = 5e-54
Identities = 142/363 (39%), Positives = 187/363 (51%), Gaps = 73/363 (20%)
Query: 34 GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQET 93
G G VNQLGGVF+NGRPLP+ +R +IVE+AH G+RPC ISRQLRVSHGCVSKIL RY ET
Sbjct: 16 GHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYET 75
Query: 94 GSIRPGAIGGSKPRQVATPDVEKKIEEYKRENPGMFSWEIRDRLLKDGHCDRSTVPSVSS 153
GSI+PG IGGSKP+ VATP V KI EYKR+NP MF+WEIRDRLL +G CD TVPSVSS
Sbjct: 76 GSIKPGVIGGSKPK-VATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSVSS 134
Query: 154 ISRVLRIKFGKK--------------------EEEDEADKKEDDGEKKAKHSIDGIL--- 190
I+R++R K + + +SI+GIL
Sbjct: 135 INRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASNDPVGSYSINGILGIP 194
Query: 191 ---GDKGNR--------------------------LDEGS--DVESEPDLPLKRKQRRSR 219
G+K R + EGS + +S+ + RK R+
Sbjct: 195 RSNGEKRKRDEVEVYTDPAHIRGGGGLHLVWTLRDVSEGSVPNGDSQSGVDSLRKHLRA- 253
Query: 220 TTFTAEQLEELEKAFERTHYPDIYTREELAQRTKLTEARVQVWF-------SNRRARWRK 272
TFT +QLE L++ FER YPD++ E + + E + S+ A
Sbjct: 254 DTFTQQQLEALDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGLDEVKSSLSASTNP 313
Query: 273 QAGANQLAAFNHLLPGG--FPPTGMPTLPPYQLP--DSTYPTTTI------SQDGGSTVH 322
+ G+N + + G T +P PP+ P +YPT+T+ S+ G+
Sbjct: 314 ELGSNVSGTQTYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAGMVPGSEFSGNPYS 373
Query: 323 RPQ 325
PQ
Sbjct: 374 HPQ 376
>gi|7524363 paired box 8 isoform PAX8C [Homo sapiens]
Length = 398
Score = 206 bits (525), Expect = 3e-53
Identities = 155/413 (37%), Positives = 196/413 (47%), Gaps = 84/413 (20%)
Query: 34 GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQET 93
G G +NQLGG F+NGRPLP +R +IV++AH G+RPC ISRQLRVSHGCVSKIL RY ET
Sbjct: 9 GHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSKILGRYYET 68
Query: 94 GSIRPGAIGGSKPRQVATPDVEKKIEEYKRENPGMFSWEIRDRLLKDGHCDRSTVPSVSS 153
GSIRPG IGGSKP+ VATP V +KI +YKR+NP MF+WEIRDRLL +G CD TVPSVSS
Sbjct: 69 GSIRPGVIGGSKPK-VATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDNDTVPSVSS 127
Query: 154 ISRVLRIK----FGKKEEEDEADKKEDDGEK------------------KAKHSIDGILG 191
I+R++R K F + A K G + +SI+G+LG
Sbjct: 128 INRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTYSINGLLG 187
Query: 192 ------DKGNRLDEGSD-----VESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTHYP 240
DK D D ++S+ RK R+ F+ LE LE FER HYP
Sbjct: 188 IAQPGSDKRKMDDSDQDSCRLSIDSQSSSSGPRKHLRT-DAFSQHHLEPLECPFERQHYP 246
Query: 241 DIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPTGMPTLPP 300
+ Y + + + G L N L G TL P
Sbjct: 247 EAYASP---------------------SHTKGEQGLYPLPLLNSTL-----DDGKATLTP 280
Query: 301 YQLP-------DSTYPTTTI-------SQDGGSTVHRPQP-LPPSTMHQGGLAAAAAAAD 345
P TYP GS P P LPP T G + A ++
Sbjct: 281 SNTPLGRNLSTHQTYPVVAAPPFWICSKSAPGSRPSMPFPMLPPCT----GSSRARPSSQ 336
Query: 346 TSSAYGARHSFSSYSDSFMNPAAPSNHMNPVSNGLSPQVMSILGNPSAVPPQP 398
+G R + + +P A M P+ + Q ++ L P A PP P
Sbjct: 337 GERWWGPRCPDTHPT----SPPADRAAMPPLPSQAWWQEVNTLAMPMATPPTP 385
>gi|7524365 paired box 8 isoform PAX8D [Homo sapiens]
Length = 321
Score = 205 bits (522), Expect = 7e-53
Identities = 120/243 (49%), Positives = 147/243 (60%), Gaps = 35/243 (14%)
Query: 34 GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQET 93
G G +NQLGG F+NGRPLP +R +IV++AH G+RPC ISRQLRVSHGCVSKIL RY ET
Sbjct: 9 GHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSKILGRYYET 68
Query: 94 GSIRPGAIGGSKPRQVATPDVEKKIEEYKRENPGMFSWEIRDRLLKDGHCDRSTVPSVSS 153
GSIRPG IGGSKP+ VATP V +KI +YKR+NP MF+WEIRDRLL +G CD TVPSVSS
Sbjct: 69 GSIRPGVIGGSKPK-VATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDNDTVPSVSS 127
Query: 154 ISRVLRIK----FGKKEEEDEADKKEDDGEK------------------KAKHSIDGILG 191
I+R++R K F + A K G + +SI+G+LG
Sbjct: 128 INRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTYSINGLLG 187
Query: 192 ------DKGNRLDEGSD-----VESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTHYP 240
DK D D ++S+ RK R+ F+ LE LE FER HYP
Sbjct: 188 IAQPGSDKRKMDDSDQDSCRLSIDSQSSSSGPRKHLRT-DAFSQHHLEPLECPFERQHYP 246
Query: 241 DIY 243
+ Y
Sbjct: 247 EAY 249
>gi|7669542 paired box 8 isoform PAX8E [Homo sapiens]
Length = 287
Score = 205 bits (522), Expect = 7e-53
Identities = 120/243 (49%), Positives = 147/243 (60%), Gaps = 35/243 (14%)
Query: 34 GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQET 93
G G +NQLGG F+NGRPLP +R +IV++AH G+RPC ISRQLRVSHGCVSKIL RY ET
Sbjct: 9 GHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSKILGRYYET 68
Query: 94 GSIRPGAIGGSKPRQVATPDVEKKIEEYKRENPGMFSWEIRDRLLKDGHCDRSTVPSVSS 153
GSIRPG IGGSKP+ VATP V +KI +YKR+NP MF+WEIRDRLL +G CD TVPSVSS
Sbjct: 69 GSIRPGVIGGSKPK-VATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDNDTVPSVSS 127
Query: 154 ISRVLRIK----FGKKEEEDEADKKEDDGEK------------------KAKHSIDGILG 191
I+R++R K F + A K G + +SI+G+LG
Sbjct: 128 INRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTYSINGLLG 187
Query: 192 ------DKGNRLDEGSD-----VESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTHYP 240
DK D D ++S+ RK R+ F+ LE LE FER HYP
Sbjct: 188 IAQPGSDKRKMDDSDQDSCRLSIDSQSSSSGPRKHLRT-DAFSQHHLEPLECPFERQHYP 246
Query: 241 DIY 243
+ Y
Sbjct: 247 EAY 249
>gi|5803117 paired box 8 isoform PAX8A [Homo sapiens]
Length = 450
Score = 205 bits (522), Expect = 7e-53
Identities = 120/243 (49%), Positives = 147/243 (60%), Gaps = 35/243 (14%)
Query: 34 GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQET 93
G G +NQLGG F+NGRPLP +R +IV++AH G+RPC ISRQLRVSHGCVSKIL RY ET
Sbjct: 9 GHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSKILGRYYET 68
Query: 94 GSIRPGAIGGSKPRQVATPDVEKKIEEYKRENPGMFSWEIRDRLLKDGHCDRSTVPSVSS 153
GSIRPG IGGSKP+ VATP V +KI +YKR+NP MF+WEIRDRLL +G CD TVPSVSS
Sbjct: 69 GSIRPGVIGGSKPK-VATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDNDTVPSVSS 127
Query: 154 ISRVLRIK----FGKKEEEDEADKKEDDGEK------------------KAKHSIDGILG 191
I+R++R K F + A K G + +SI+G+LG
Sbjct: 128 INRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTYSINGLLG 187
Query: 192 ------DKGNRLDEGSD-----VESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTHYP 240
DK D D ++S+ RK R+ F+ LE LE FER HYP
Sbjct: 188 IAQPGSDKRKMDDSDQDSCRLSIDSQSSSSGPRKHLRT-DAFSQHHLEPLECPFERQHYP 246
Query: 241 DIY 243
+ Y
Sbjct: 247 EAY 249
>gi|197276661 paired box 1 [Homo sapiens]
Length = 534
Score = 193 bits (490), Expect = 4e-49
Identities = 103/160 (64%), Positives = 120/160 (75%), Gaps = 7/160 (4%)
Query: 8 VPRMMRPAPGQNYPRTGFPLEVSTPLGQ----GRVNQLGGVFINGRPLPNHIRHKIVEMA 63
+P P+PG +P +++ PL G VNQLGGVF+NGRPLPN IR +IVE+A
Sbjct: 70 LPDCAGPSPG--HPGHPGARQLAGPLAMEQTYGEVNQLGGVFVNGRPLPNAIRLRIVELA 127
Query: 64 HHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPRQVATPDVEKKIEEYKR 123
GIRPC ISRQLRVSHGCVSKIL RY ETGSI PGAIGGSKPR V TP+V K I +YK+
Sbjct: 128 QLGIRPCDISRQLRVSHGCVSKILARYNETGSILPGAIGGSKPR-VTTPNVVKHIRDYKQ 186
Query: 124 ENPGMFSWEIRDRLLKDGHCDRSTVPSVSSISRVLRIKFG 163
+PG+F+WEIRDRLL DG CD+ VPSVSSISR+LR K G
Sbjct: 187 GDPGIFAWEIRDRLLADGVCDKYNVPSVSSISRILRNKIG 226
>gi|7242167 paired box 9 [Homo sapiens]
Length = 341
Score = 191 bits (486), Expect = 1e-48
Identities = 97/137 (70%), Positives = 108/137 (78%), Gaps = 1/137 (0%)
Query: 36 GRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGS 95
G VNQLGGVF+NGRPLPN IR +IVE+A GIRPC ISRQLRVSHGCVSKIL RY ETGS
Sbjct: 6 GEVNQLGGVFVNGRPLPNAIRLRIVELAQLGIRPCDISRQLRVSHGCVSKILARYNETGS 65
Query: 96 IRPGAIGGSKPRQVATPDVEKKIEEYKRENPGMFSWEIRDRLLKDGHCDRSTVPSVSSIS 155
I PGAIGGSKPR V TP V K I YK+ +PG+F+WEIRDRLL DG CD+ VPSVSSIS
Sbjct: 66 ILPGAIGGSKPR-VTTPTVVKHIRTYKQRDPGIFAWEIRDRLLADGVCDKYNVPSVSSIS 124
Query: 156 RVLRIKFGKKEEEDEAD 172
R+LR K G ++ D
Sbjct: 125 RILRNKIGNLAQQGHYD 141
>gi|170784824 paired box 4 [Homo sapiens]
Length = 343
Score = 191 bits (485), Expect = 1e-48
Identities = 128/325 (39%), Positives = 167/325 (51%), Gaps = 43/325 (13%)
Query: 38 VNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIR 97
+NQLGG+F+NGRPLP R +IV +A G+RPC ISR L+VS+GCVSKIL RY TG +
Sbjct: 1 MNQLGGLFVNGRPLPLDTRQQIVRLAVSGMRPCDISRILKVSNGCVSKILGRYYRTGVLE 60
Query: 98 PGAIGGSKPRQVATPDVEKKIEEYKRENPGMFSWEIRDRLLKDGHCDRSTVPSVSSISRV 157
P IGGSKPR +ATP V +I + K E P +F+WEI+ +L +G C + PSVSSI+RV
Sbjct: 61 PKGIGGSKPR-LATPPVVARIAQLKGECPALFAWEIQRQLCAEGLCTQDKTPSVSSINRV 119
Query: 158 LRIKFGKKEEEDEADKKEDDGEKKAKHSIDGILGDKGNRLDEGSDVESEPDLPLKRKQRR 217
LR +ED G + +L GS+ P R
Sbjct: 120 LRA------------LQEDQGLPCTRLRSPAVLAPAVLTPHSGSET---PRGTHPGTGHR 164
Query: 218 SRTTFTAEQLEELEKAFERTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQ---- 273
+RT F+ Q E LEK F+R YPD R +LA T L E V+VWFSNRRA+WR+Q
Sbjct: 165 NRTIFSPSQAEALEKEFQRGQYPDSVARGKLATATSLPEDTVRVWFSNRRAKWRRQEKLK 224
Query: 274 -----AGANQLAAFNHLL---------PGGFPPTGMPTLPP-----YQLPDSTYPTTTIS 314
GA+Q + PG P +P L P YQL +T P +S
Sbjct: 225 WEMQLPGASQGLTVPRVAPGIISAQQSPGSVPTAALPALEPLGPSCYQLCWATAPERCLS 284
Query: 315 QDGGSTVHRP----QPLPPSTMHQG 335
+P P P+++ G
Sbjct: 285 DTPPKACLKPCWGHLPPQPNSLDSG 309
>gi|24497589 aristaless related homeobox [Homo sapiens]
Length = 562
Score = 114 bits (285), Expect = 2e-25
Identities = 76/158 (48%), Positives = 91/158 (57%), Gaps = 22/158 (13%)
Query: 187 DGILGDKGNRLDEGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTHYPDIYTRE 246
+G G+ L GSD SE L LKRKQRR RTTFT+ QLEELE+AF++THYPD++TRE
Sbjct: 303 EGKDGEDSVCLSAGSD--SEEGL-LKRKQRRYRTTFTSYQLEELERAFQKTHYPDVFTRE 359
Query: 247 ELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPTGMPTLPPYQLPDS 306
ELA R LTEARVQVWF NRRA+WRK+ A A H P G+P P +
Sbjct: 360 ELAMRLDLTEARVQVWFQNRRAKWRKREKA---GAQTH-------PPGLPFPGPL---SA 406
Query: 307 TYPTTTISQDGGSTVHRPQPLPPSTMHQGGLAAAAAAA 344
T+P + H P + AAAAAAA
Sbjct: 407 THPLSPYLDASPFPPHHP------ALDSAWTAAAAAAA 438
>gi|113204604 aristaless-like homeobox 3 [Homo sapiens]
Length = 343
Score = 112 bits (280), Expect = 8e-25
Identities = 68/192 (35%), Positives = 101/192 (52%), Gaps = 13/192 (6%)
Query: 212 KRKQRRSRTTFTAEQLEELEKAFERTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWR 271
K K+RR+RTTF+ QLEELEK F++THYPD+Y RE+LA RT LTEARVQVWF NRRA+WR
Sbjct: 150 KSKKRRNRTTFSTFQLEELEKVFQKTHYPDVYAREQLALRTDLTEARVQVWFQNRRAKWR 209
Query: 272 KQAGANQLAAFNHLLPGGFPPTGMPTLPPY-QLPDSTYPTTTISQDGGSTVHRPQPLP-- 328
K+ ++ + + + +P + QL +S + + GG + P+ +P
Sbjct: 210 KRERYGKIQEGRNPFTAAYDISVLPRTDSHPQLQNSLWASPGSGSPGGPCLVSPEGIPSP 269
Query: 329 ---PSTMHQGGLAAAAAAADTSSAYGARHSFSSYSDSFMNPAAPSNHMNPVSNG--LSPQ 383
P + G +A S+A+ +S + P + P S+G SP
Sbjct: 270 CMSPYSHPHGSVAGFMGVPAPSAAHPGIYSIHGFP-----PTLGGHSFEPSSDGDYKSPS 324
Query: 384 VMSILGNPSAVP 395
++S+ P P
Sbjct: 325 LVSLRVKPKEPP 336
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.131 0.395
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,154,143
Number of Sequences: 37866
Number of extensions: 1349473
Number of successful extensions: 6757
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 325
Number of HSP's successfully gapped in prelim test: 289
Number of HSP's that attempted gapping in prelim test: 5813
Number of HSP's gapped (non-prelim): 1111
length of query: 518
length of database: 18,247,518
effective HSP length: 107
effective length of query: 411
effective length of database: 14,195,856
effective search space: 5834496816
effective search space used: 5834496816
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.