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Search of human proteins with 74959747
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|74959747 Fanconi anemia, complementation group M [Homo
sapiens]
(2048 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|74959747 Fanconi anemia, complementation group M [Homo sapiens] 4085 0.0
gi|27881482 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide RIG-I [... 99 4e-20
gi|149408122 RNA helicase LGP2 [Homo sapiens] 74 1e-12
gi|27886568 interferon induced with helicase C domain 1 [Homo sa... 70 2e-11
gi|29294649 dicer1 [Homo sapiens] 66 4e-10
gi|29294651 dicer1 [Homo sapiens] 66 4e-10
gi|4885217 excision repair cross-complementing rodent repair def... 60 2e-08
gi|224593278 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 [Homo sap... 54 1e-06
gi|50659095 DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 [Homo sapi... 54 2e-06
gi|7661920 eukaryotic translation initiation factor 4A, isoform ... 50 2e-05
gi|13129006 nucleolar protein GU2 [Homo sapiens] 50 3e-05
gi|38327634 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 [Homo sapi... 48 1e-04
gi|21071032 DEAD-box protein abstrakt [Homo sapiens] 47 2e-04
gi|148762940 DVL-binding protein DAPLE [Homo sapiens] 47 2e-04
gi|216548091 leucine zipper protein 1 [Homo sapiens] 47 3e-04
gi|216548085 leucine zipper protein 1 [Homo sapiens] 47 3e-04
gi|217330641 IWS1 homolog [Homo sapiens] 47 3e-04
gi|87196351 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3 [Homo... 46 3e-04
gi|169881239 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked ... 46 4e-04
gi|13514809 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked [... 46 4e-04
gi|76880486 activating signal cointegrator 1 complex subunit 3 i... 45 6e-04
gi|188035877 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 [Homo sap... 45 6e-04
gi|154759257 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51 [Homo sap... 45 6e-04
gi|209862869 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 3 ... 44 0.001
gi|13518015 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 1 [... 44 0.001
gi|216548263 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 2 ... 44 0.001
gi|31542656 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 [Homo sapi... 44 0.001
gi|38788333 remodeling and spacing factor 1 [Homo sapiens] 44 0.002
gi|149944526 additional sex combs like 3 [Homo sapiens] 44 0.002
gi|45446747 DEAD box polypeptide 42 protein [Homo sapiens] 44 0.002
>gi|74959747 Fanconi anemia, complementation group M [Homo sapiens]
Length = 2048
Score = 4085 bits (10593), Expect = 0.0
Identities = 2048/2048 (100%), Positives = 2048/2048 (100%)
Query: 1 MSGRQRTLFQTWGSSISRSSGTPGCSSGTERPQSPGSSKAPLPAAAEAQLESDDDVLLVA 60
MSGRQRTLFQTWGSSISRSSGTPGCSSGTERPQSPGSSKAPLPAAAEAQLESDDDVLLVA
Sbjct: 1 MSGRQRTLFQTWGSSISRSSGTPGCSSGTERPQSPGSSKAPLPAAAEAQLESDDDVLLVA 60
Query: 61 AYEAERQLCLENGGFCTSAGALWIYPTNCPVRDYQLHISRAALFCNTLVCLPTGLGKTFI 120
AYEAERQLCLENGGFCTSAGALWIYPTNCPVRDYQLHISRAALFCNTLVCLPTGLGKTFI
Sbjct: 61 AYEAERQLCLENGGFCTSAGALWIYPTNCPVRDYQLHISRAALFCNTLVCLPTGLGKTFI 120
Query: 121 AAVVMYNFYRWFPSGKVVFMAPTKPLVTQQIEACYQVMGIPQSHMAEMTGSTQASTRKEI 180
AAVVMYNFYRWFPSGKVVFMAPTKPLVTQQIEACYQVMGIPQSHMAEMTGSTQASTRKEI
Sbjct: 121 AAVVMYNFYRWFPSGKVVFMAPTKPLVTQQIEACYQVMGIPQSHMAEMTGSTQASTRKEI 180
Query: 181 WCSKRVLFLTPQVMVNDLSRGACPAAEIKCLVIDEAHKALGNYAYCQVVRELVKYTNHFR 240
WCSKRVLFLTPQVMVNDLSRGACPAAEIKCLVIDEAHKALGNYAYCQVVRELVKYTNHFR
Sbjct: 181 WCSKRVLFLTPQVMVNDLSRGACPAAEIKCLVIDEAHKALGNYAYCQVVRELVKYTNHFR 240
Query: 241 ILALSATPGSDIKAVQQVITNLLIGQIELRSEDSPDILTYSHERKVEKLIVPLGEELAAI 300
ILALSATPGSDIKAVQQVITNLLIGQIELRSEDSPDILTYSHERKVEKLIVPLGEELAAI
Sbjct: 241 ILALSATPGSDIKAVQQVITNLLIGQIELRSEDSPDILTYSHERKVEKLIVPLGEELAAI 300
Query: 301 QKTYIQILESFARSLIQRNVLMRRDIPNLTKYQIILARDQFRKNPSPNIVGIQQGIIEGE 360
QKTYIQILESFARSLIQRNVLMRRDIPNLTKYQIILARDQFRKNPSPNIVGIQQGIIEGE
Sbjct: 301 QKTYIQILESFARSLIQRNVLMRRDIPNLTKYQIILARDQFRKNPSPNIVGIQQGIIEGE 360
Query: 361 FAICISLYHGYELLQQMGMRSLYFFLCGIMDGTKGMTRSKNELGRNEDFMKLYNHLECMF 420
FAICISLYHGYELLQQMGMRSLYFFLCGIMDGTKGMTRSKNELGRNEDFMKLYNHLECMF
Sbjct: 361 FAICISLYHGYELLQQMGMRSLYFFLCGIMDGTKGMTRSKNELGRNEDFMKLYNHLECMF 420
Query: 421 ARTRSTSANGISAIQQGDKNKKFVYSHPKLKKLEEVVIEHFKSWNAENTTEKKRDETRVM 480
ARTRSTSANGISAIQQGDKNKKFVYSHPKLKKLEEVVIEHFKSWNAENTTEKKRDETRVM
Sbjct: 421 ARTRSTSANGISAIQQGDKNKKFVYSHPKLKKLEEVVIEHFKSWNAENTTEKKRDETRVM 480
Query: 481 IFSSFRDSVQEIAEMLSQHQPIIRVMTFVGHASGKSTKGFTQKEQLEVVKQFRDGGYNTL 540
IFSSFRDSVQEIAEMLSQHQPIIRVMTFVGHASGKSTKGFTQKEQLEVVKQFRDGGYNTL
Sbjct: 481 IFSSFRDSVQEIAEMLSQHQPIIRVMTFVGHASGKSTKGFTQKEQLEVVKQFRDGGYNTL 540
Query: 541 VSTCVGEEGLDIGEVDLIICFDSQKSPIRLVQRMGRTGRKRQGRIVIILSEGREERIYNQ 600
VSTCVGEEGLDIGEVDLIICFDSQKSPIRLVQRMGRTGRKRQGRIVIILSEGREERIYNQ
Sbjct: 541 VSTCVGEEGLDIGEVDLIICFDSQKSPIRLVQRMGRTGRKRQGRIVIILSEGREERIYNQ 600
Query: 601 SQSNKRSIYKAISSNRQVLHFYQRSPRMVPDGINPKLHKMFITHGVYEPEKPSRNLQRKS 660
SQSNKRSIYKAISSNRQVLHFYQRSPRMVPDGINPKLHKMFITHGVYEPEKPSRNLQRKS
Sbjct: 601 SQSNKRSIYKAISSNRQVLHFYQRSPRMVPDGINPKLHKMFITHGVYEPEKPSRNLQRKS 660
Query: 661 SIFSYRDGMRQSSLKKDWFLSEEEFKLWNRLYRLRDSDEIKEITLPQVQFSSLQNEENKP 720
SIFSYRDGMRQSSLKKDWFLSEEEFKLWNRLYRLRDSDEIKEITLPQVQFSSLQNEENKP
Sbjct: 661 SIFSYRDGMRQSSLKKDWFLSEEEFKLWNRLYRLRDSDEIKEITLPQVQFSSLQNEENKP 720
Query: 721 AQESTTGIHQLSLSEWRLWQDHPLPTHQVDHSDRCRHFIGLMQMIEGMRHEEGECSYELE 780
AQESTTGIHQLSLSEWRLWQDHPLPTHQVDHSDRCRHFIGLMQMIEGMRHEEGECSYELE
Sbjct: 721 AQESTTGIHQLSLSEWRLWQDHPLPTHQVDHSDRCRHFIGLMQMIEGMRHEEGECSYELE 780
Query: 781 VESYLQMEDVTSTFIAPRNESNNLASDTFITHKKSSFIKNINQGSSSSVIESDEECAEIV 840
VESYLQMEDVTSTFIAPRNESNNLASDTFITHKKSSFIKNINQGSSSSVIESDEECAEIV
Sbjct: 781 VESYLQMEDVTSTFIAPRNESNNLASDTFITHKKSSFIKNINQGSSSSVIESDEECAEIV 840
Query: 841 KQTHIKPTKIVSLKKKVSKEIKKDQLKKENNHGIIDSVDNDRNSTVENIFQEDLPNDKRT 900
KQTHIKPTKIVSLKKKVSKEIKKDQLKKENNHGIIDSVDNDRNSTVENIFQEDLPNDKRT
Sbjct: 841 KQTHIKPTKIVSLKKKVSKEIKKDQLKKENNHGIIDSVDNDRNSTVENIFQEDLPNDKRT 900
Query: 901 SDTDEIAATCTINENVIKEPCVLLTECQFTNKSTSSLAGNVLDSGYNSFNDEKSVSSNLF 960
SDTDEIAATCTINENVIKEPCVLLTECQFTNKSTSSLAGNVLDSGYNSFNDEKSVSSNLF
Sbjct: 901 SDTDEIAATCTINENVIKEPCVLLTECQFTNKSTSSLAGNVLDSGYNSFNDEKSVSSNLF 960
Query: 961 LPFEEELYIVRTDDQFYNCHSLTKEVLANVERFLSYSPPPLSGLSDLEYEIAKGTALENL 1020
LPFEEELYIVRTDDQFYNCHSLTKEVLANVERFLSYSPPPLSGLSDLEYEIAKGTALENL
Sbjct: 961 LPFEEELYIVRTDDQFYNCHSLTKEVLANVERFLSYSPPPLSGLSDLEYEIAKGTALENL 1020
Query: 1021 LFLPCAEHLRSDKCTCLLSHSAVNSQQNLELNSLKCINYPSEKSCLYDIPNDNISDEPSL 1080
LFLPCAEHLRSDKCTCLLSHSAVNSQQNLELNSLKCINYPSEKSCLYDIPNDNISDEPSL
Sbjct: 1021 LFLPCAEHLRSDKCTCLLSHSAVNSQQNLELNSLKCINYPSEKSCLYDIPNDNISDEPSL 1080
Query: 1081 CDCDVHKHNQNENLVPNNRVQIHRSPAQNLVGENNHDVDNSDLPVLSTDQDESLLLFEDV 1140
CDCDVHKHNQNENLVPNNRVQIHRSPAQNLVGENNHDVDNSDLPVLSTDQDESLLLFEDV
Sbjct: 1081 CDCDVHKHNQNENLVPNNRVQIHRSPAQNLVGENNHDVDNSDLPVLSTDQDESLLLFEDV 1140
Query: 1141 NTEFDDVSLSPLNSKSESLPVSDKTAISETPLVSQFLISDELLLDNNSELQDQITRDANS 1200
NTEFDDVSLSPLNSKSESLPVSDKTAISETPLVSQFLISDELLLDNNSELQDQITRDANS
Sbjct: 1141 NTEFDDVSLSPLNSKSESLPVSDKTAISETPLVSQFLISDELLLDNNSELQDQITRDANS 1200
Query: 1201 FKSRDQRGVQEEKVKNHEDIFDCSRDLFSVTFDLGFCSPDSDDEILEHTSDSNRPLDDLY 1260
FKSRDQRGVQEEKVKNHEDIFDCSRDLFSVTFDLGFCSPDSDDEILEHTSDSNRPLDDLY
Sbjct: 1201 FKSRDQRGVQEEKVKNHEDIFDCSRDLFSVTFDLGFCSPDSDDEILEHTSDSNRPLDDLY 1260
Query: 1261 GRYLEIKEISDANYVSNQALIPRDHSKNFTSGTVIIPSNEDMQNPNYVHLPLSAAKNEEL 1320
GRYLEIKEISDANYVSNQALIPRDHSKNFTSGTVIIPSNEDMQNPNYVHLPLSAAKNEEL
Sbjct: 1261 GRYLEIKEISDANYVSNQALIPRDHSKNFTSGTVIIPSNEDMQNPNYVHLPLSAAKNEEL 1320
Query: 1321 LSPGYSQFSLPVQKKVMSTPLSKSNTLNSFSKIRKEILKTPDSSKEKVNLQRFKEALNST 1380
LSPGYSQFSLPVQKKVMSTPLSKSNTLNSFSKIRKEILKTPDSSKEKVNLQRFKEALNST
Sbjct: 1321 LSPGYSQFSLPVQKKVMSTPLSKSNTLNSFSKIRKEILKTPDSSKEKVNLQRFKEALNST 1380
Query: 1381 FDYSEFSLEKSKSSGPMYLHKSCHSVEDGQLLTSNESEDDEIFRRKVKRAKGNVLNSPED 1440
FDYSEFSLEKSKSSGPMYLHKSCHSVEDGQLLTSNESEDDEIFRRKVKRAKGNVLNSPED
Sbjct: 1381 FDYSEFSLEKSKSSGPMYLHKSCHSVEDGQLLTSNESEDDEIFRRKVKRAKGNVLNSPED 1440
Query: 1441 QKNSEVDSPLHAVKKRRFPINRSELSSSDESENFPKPCSQLEDFKVCNGNARRGIKVPKR 1500
QKNSEVDSPLHAVKKRRFPINRSELSSSDESENFPKPCSQLEDFKVCNGNARRGIKVPKR
Sbjct: 1441 QKNSEVDSPLHAVKKRRFPINRSELSSSDESENFPKPCSQLEDFKVCNGNARRGIKVPKR 1500
Query: 1501 QSHLKHVARKFLDDEAELSEEDAEYVSSDENDESENEQDSSLLDFLNDETQLSQAINDSE 1560
QSHLKHVARKFLDDEAELSEEDAEYVSSDENDESENEQDSSLLDFLNDETQLSQAINDSE
Sbjct: 1501 QSHLKHVARKFLDDEAELSEEDAEYVSSDENDESENEQDSSLLDFLNDETQLSQAINDSE 1560
Query: 1561 MRAIYMKSLRSPMMNNKYKMIHKTHKNINIFSQIPEQDETYLEDSFCVDEEESCKGQSSE 1620
MRAIYMKSLRSPMMNNKYKMIHKTHKNINIFSQIPEQDETYLEDSFCVDEEESCKGQSSE
Sbjct: 1561 MRAIYMKSLRSPMMNNKYKMIHKTHKNINIFSQIPEQDETYLEDSFCVDEEESCKGQSSE 1620
Query: 1621 EEVCVDFNLITDDCFANSKKYKTRRAVMLKEMMEQNCAHSKKKLSRIILPDDSSEEENNV 1680
EEVCVDFNLITDDCFANSKKYKTRRAVMLKEMMEQNCAHSKKKLSRIILPDDSSEEENNV
Sbjct: 1621 EEVCVDFNLITDDCFANSKKYKTRRAVMLKEMMEQNCAHSKKKLSRIILPDDSSEEENNV 1680
Query: 1681 NDKRESNIAVNPSTVKKNKQQDHCLNSVPSGSSAQSKVRSTPRVNPLAKQSKQTSLNLKD 1740
NDKRESNIAVNPSTVKKNKQQDHCLNSVPSGSSAQSKVRSTPRVNPLAKQSKQTSLNLKD
Sbjct: 1681 NDKRESNIAVNPSTVKKNKQQDHCLNSVPSGSSAQSKVRSTPRVNPLAKQSKQTSLNLKD 1740
Query: 1741 TISEVSDFKPQNHNEVQSTTPPFTTVDSQKDCRKFPVPQKDGSALEDSSTSGASCSKSRP 1800
TISEVSDFKPQNHNEVQSTTPPFTTVDSQKDCRKFPVPQKDGSALEDSSTSGASCSKSRP
Sbjct: 1741 TISEVSDFKPQNHNEVQSTTPPFTTVDSQKDCRKFPVPQKDGSALEDSSTSGASCSKSRP 1800
Query: 1801 HLAGTHTSLRLPQEGKGTCILVGGHEITSGLEVISSLRAIHGLQVEVCPLNGCDYIVSNR 1860
HLAGTHTSLRLPQEGKGTCILVGGHEITSGLEVISSLRAIHGLQVEVCPLNGCDYIVSNR
Sbjct: 1801 HLAGTHTSLRLPQEGKGTCILVGGHEITSGLEVISSLRAIHGLQVEVCPLNGCDYIVSNR 1860
Query: 1861 MVVERRSQSEMLNSVNKNKFIEQIQHLQSMFERICVIVEKDREKTGDTSRMFRRTKSYDS 1920
MVVERRSQSEMLNSVNKNKFIEQIQHLQSMFERICVIVEKDREKTGDTSRMFRRTKSYDS
Sbjct: 1861 MVVERRSQSEMLNSVNKNKFIEQIQHLQSMFERICVIVEKDREKTGDTSRMFRRTKSYDS 1920
Query: 1921 LLTTLIGAGIRILFSSCQEETADLLKELSLVEQRKNVGIHVPTVVNSNKSEALQFYLSIP 1980
LLTTLIGAGIRILFSSCQEETADLLKELSLVEQRKNVGIHVPTVVNSNKSEALQFYLSIP
Sbjct: 1921 LLTTLIGAGIRILFSSCQEETADLLKELSLVEQRKNVGIHVPTVVNSNKSEALQFYLSIP 1980
Query: 1981 NISYITALNMCHQFSSVKRMANSSLQEISMYAQVTHQKAEEIYRYIHYVFDIQMLPNDLN 2040
NISYITALNMCHQFSSVKRMANSSLQEISMYAQVTHQKAEEIYRYIHYVFDIQMLPNDLN
Sbjct: 1981 NISYITALNMCHQFSSVKRMANSSLQEISMYAQVTHQKAEEIYRYIHYVFDIQMLPNDLN 2040
Query: 2041 QDRLKSDI 2048
QDRLKSDI
Sbjct: 2041 QDRLKSDI 2048
>gi|27881482 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide RIG-I
[Homo sapiens]
Length = 925
Score = 99.0 bits (245), Expect = 4e-20
Identities = 135/609 (22%), Positives = 262/609 (43%), Gaps = 107/609 (17%)
Query: 92 RDYQLHISRAALFC-NTLVCLPTGLGKTFIAAVVMYNFYRWFP---SGKVVFMAPTKPLV 147
R+YQL ++ A+ NT++C PTG GKTF++ ++ + + FP GKVVF A P+
Sbjct: 244 RNYQLELALPAMKGKNTIICAPTGCGKTFVSLLICEHHLKKFPQGQKGKVVFFANQIPVY 303
Query: 148 TQQIEACYQVMGIPQSHMAEMTGSTQASTR----KEIWCSKRVLFLTPQVMVNDLSRGAC 203
QQ + + H +TG + A+ ++I + ++ LTPQ++VN+L +G
Sbjct: 304 EQQKSVFSKYF---ERHGYRVTGISGATAENVPVEQIVENNDIIILTPQILVNNLKKGTI 360
Query: 204 PAAEIKCLVI-DEAHKALGNYAYCQVVRELVKYTNHF---------RILALSATPG-SDI 252
P+ I L+I DE H + Y + + Y + +++ L+A+ G D
Sbjct: 361 PSLSIFTLMIFDECHNTSKQHPYNMI---MFNYLDQKLGGSSGPLPQVIGLTASVGVGDA 417
Query: 253 KAVQQVITNL----------LIGQIELRSEDSPDILTYSHERKVEKLIVPLGEELAAIQK 302
K + + + +I ++ E+ ++ Y ++ K+ + ++ I
Sbjct: 418 KNTDEALDYICKLCASLDASVIATVKHNLEELEQVV-YKPQKFFRKVESRISDKFKYIIA 476
Query: 303 TYIQILESFARSLIQRNVLMRRDIPNLTKYQIILARDQFRKNPSPNIVGIQQGIIEGEFA 362
++ ES A+ + +D+ NL++ Q R+ + IV +Q+
Sbjct: 477 QLMRDTESLAKRIC-------KDLENLSQIQ---NREFGTQKYEQWIVTVQKA------- 519
Query: 363 ICISLYHGYELLQQMGMRSLYFFLCGIMDGTKGMTRSKNELGRNEDFMKLYNHLECMFAR 422
C+ + + ++L+ + + + S E R +D + ++L+ F+
Sbjct: 520 -CMVFQMPDKDEESRICKALFLYTSHLRKYNDALIIS--EHARMKDAL---DYLKDFFSN 573
Query: 423 TRSTSANGISAIQQGDKNKKFVYSHPKLKKLEEVVIEHFKSWNAENTTEKKRD------- 475
R A G I+Q D ++F KL++LE V S + N K D
Sbjct: 574 VR---AAGFDEIEQ-DLTQRF---EEKLQELESV------SRDPSNENPKLEDLCFILQE 620
Query: 476 ------ETRVMIFSSFRDSVQEIAEMLSQHQPI--IRVMTFVGHASGKSTKGFTQKEQLE 527
ET ++F R V + + + + ++ G G T Q
Sbjct: 621 EYHLNPETITILFVKTRALVDALKNWIEGNPKLSFLKPGILTGRGKTNQNTGMTLPAQKC 680
Query: 528 VVKQFR-DGGYNTLVSTCVGEEGLDIGEVDLIICFDSQKSPIRLVQRMGRTGRKRQGRIV 586
++ F+ G +N L++T V +EG+DI + +L+I ++ + I+++Q GR GR R +
Sbjct: 681 ILDAFKASGDHNILIATSVADEGIDIAQCNLVILYEYVGNVIKMIQTRGR-GRARGSKCF 739
Query: 587 IILSEG----------REERIYNQS----QSNKRSIYKA----ISSNRQVLHFYQRSPRM 628
++ S +E++ N S Q+ ++++ I ++ + + Q P+
Sbjct: 740 LLTSNAGVIEKEQINMYKEKMMNDSILRLQTWDEAVFREKILHIQTHEKFIRDSQEKPKP 799
Query: 629 VPDGINPKL 637
VPD N KL
Sbjct: 800 VPDKENKKL 808
>gi|149408122 RNA helicase LGP2 [Homo sapiens]
Length = 678
Score = 73.9 bits (180), Expect = 1e-12
Identities = 48/153 (31%), Positives = 77/153 (50%), Gaps = 15/153 (9%)
Query: 447 HPKLKKLEEVVIEHFKSWNAENTTEKKRDETRVMIFSSFRDSVQEIAEMLSQHQPI---- 502
+PKL+ LE+++ F S N+ R +IF+ R S + L Q Q +
Sbjct: 348 NPKLEMLEKILQRQFSSSNSP----------RGIIFTRTRQSAHSLLLWLQQQQGLQTVD 397
Query: 503 IRVMTFVGHASGKSTKGFTQKEQLEVVKQFRDGGYNTLVSTCVGEEGLDIGEVDLIICFD 562
IR +G + + TQ++Q EV+++F+DG N LV+T V EEGLDI ++++ +
Sbjct: 398 IRAQLLIGAGNSSQSTHMTQRDQQEVIQKFQDGTLNLLVATSVAEEGLDIPHCNVVVRYG 457
Query: 563 SQKSPIRLVQRMGRTGRKRQGRIVIILSEGREE 595
+ I +VQ GR R Q + +EG E
Sbjct: 458 LLTNEISMVQARGR-ARADQSVYAFVATEGSRE 489
Score = 33.1 bits (74), Expect = 2.9
Identities = 24/63 (38%), Positives = 29/63 (46%), Gaps = 1/63 (1%)
Query: 91 VRDYQLHISRAALFC-NTLVCLPTGLGKTFIAAVVMYNFYRWFPSGKVVFMAPTKPLVTQ 149
+R YQ + AL N ++ LPTG GKT AA V KVV + LVTQ
Sbjct: 3 LRSYQWEVIMPALEGKNIIIWLPTGAGKTRAAAYVAKRHLETVDGAKVVVLVNRVHLVTQ 62
Query: 150 QIE 152
E
Sbjct: 63 HGE 65
>gi|27886568 interferon induced with helicase C domain 1 [Homo
sapiens]
Length = 1025
Score = 70.5 bits (171), Expect = 2e-11
Identities = 48/175 (27%), Positives = 84/175 (48%), Gaps = 19/175 (10%)
Query: 445 YSHPKLKKLEEVVIEHFKSWNAENTTEKKRDETRVMIFSSFRDSVQEIAEMLSQHQPI-- 502
Y + KL KL ++E + + + R +IF+ R S +++ +++++
Sbjct: 696 YENEKLTKLRNTIMEQYT---------RTEESARGIIFTKTRQSAYALSQWITENEKFAE 746
Query: 503 --IRVMTFVGHASGKSTKGFTQKEQLEVVKQFRDGGYNTLVSTCVGEEGLDIGEVDLIIC 560
++ +G K TQ EQ EV+ +FR G N L++T V EEGLDI E +++I
Sbjct: 747 VGVKAHHLIGAGHSSEFKPMTQNEQKEVISKFRTGKINLLIATTVAEEGLDIKECNIVIR 806
Query: 561 FDSQKSPIRLVQRMGRTGRKRQGRIVIILSEGR---EERIYNQSQSNKRSIYKAI 612
+ + I +VQ GR R + V++ G E N + ++ +YKAI
Sbjct: 807 YGLVTNEIAMVQARGR-ARADESTYVLVAHSGSGVIEHETVNDFR--EKMMYKAI 858
Score = 44.3 bits (103), Expect = 0.001
Identities = 45/185 (24%), Positives = 79/185 (42%), Gaps = 26/185 (14%)
Query: 91 VRDYQLHISRAALFC-NTLVCLPTGLGKTFIAAVVMYNFY----RWFPSGKVVFMAPTKP 145
+R YQ+ +++ AL N ++CLPTG GKT +A + + + GKV+ +
Sbjct: 308 LRPYQMEVAQPALEGKNIIICLPTGSGKTRVAVYIAKDHLDKKKKASEPGKVIVLVNKVL 367
Query: 146 LVTQQIEACYQVMGIPQSHMAEMTGSTQAS-TRKEIWCSKRVLFLTPQVMVNDL------ 198
LV Q +Q + ++G TQ + E+ S ++ T Q++ N L
Sbjct: 368 LVEQLFRKEFQPFLKKWYRVIGLSGDTQLKISFPEVVKSCDIIISTAQILENSLLNLENG 427
Query: 199 SRGACPAAEIKCLVIDEAHKALGNYAYCQVVRE--LVKYTNHF------------RILAL 244
++ ++IDE H Y ++R + K N+ +IL L
Sbjct: 428 EDAGVQLSDFSLIIIDECHHTNKEAVYNNIMRHYLMQKLKNNRLKKENKPVIPLPQILGL 487
Query: 245 SATPG 249
+A+PG
Sbjct: 488 TASPG 492
>gi|29294649 dicer1 [Homo sapiens]
Length = 1922
Score = 65.9 bits (159), Expect = 4e-10
Identities = 52/166 (31%), Positives = 79/166 (47%), Gaps = 12/166 (7%)
Query: 92 RDYQLHISRAALFCNTLVCLPTGLGKTFIAAV----VMYNFYRWFPSG--KVVFMAPTKP 145
R YQ+ + AAL NT+VCL TG GKTFIA + + Y F + VF+ +
Sbjct: 45 RKYQVELLEAALDHNTIVCLNTGSGKTFIAVLLTKELSYQIRGDFSRNGKRTVFLVNSAN 104
Query: 146 LVTQQIEACYQVMGIPQSHMAEMTGSTQASTRKEIW----CSKRVLFLTPQVMVNDLSRG 201
V QQ+ A + + + AS KE W +VL +T V +N L G
Sbjct: 105 QVAQQVSAVRTHSDLKVGEYSNL--EVNASWTKERWNQEFTKHQVLIMTCYVALNVLKNG 162
Query: 202 ACPAAEIKCLVIDEAHKALGNYAYCQVVRELVKYTNHFRILALSAT 247
++I LV DE H A+ ++ Y ++++ + RIL L+A+
Sbjct: 163 YLSLSDINLLVFDECHLAILDHPYREIMKLCENCPSCPRILGLTAS 208
Score = 41.2 bits (95), Expect = 0.011
Identities = 26/72 (36%), Positives = 38/72 (52%), Gaps = 5/72 (6%)
Query: 510 GHASGKSTKGFTQKE-----QLEVVKQFRDGGYNTLVSTCVGEEGLDIGEVDLIICFDSQ 564
GH GK+ Q E Q EV+++FR N L++T + EEG+DI + +L++ FD
Sbjct: 481 GHGIGKNQPRNKQMEAEFRKQEEVLRKFRAHETNLLIATSIVEEGVDIPKCNLVVRFDLP 540
Query: 565 KSPIRLVQRMGR 576
VQ GR
Sbjct: 541 TEYRSYVQSKGR 552
>gi|29294651 dicer1 [Homo sapiens]
Length = 1922
Score = 65.9 bits (159), Expect = 4e-10
Identities = 52/166 (31%), Positives = 79/166 (47%), Gaps = 12/166 (7%)
Query: 92 RDYQLHISRAALFCNTLVCLPTGLGKTFIAAV----VMYNFYRWFPSG--KVVFMAPTKP 145
R YQ+ + AAL NT+VCL TG GKTFIA + + Y F + VF+ +
Sbjct: 45 RKYQVELLEAALDHNTIVCLNTGSGKTFIAVLLTKELSYQIRGDFSRNGKRTVFLVNSAN 104
Query: 146 LVTQQIEACYQVMGIPQSHMAEMTGSTQASTRKEIW----CSKRVLFLTPQVMVNDLSRG 201
V QQ+ A + + + AS KE W +VL +T V +N L G
Sbjct: 105 QVAQQVSAVRTHSDLKVGEYSNL--EVNASWTKERWNQEFTKHQVLIMTCYVALNVLKNG 162
Query: 202 ACPAAEIKCLVIDEAHKALGNYAYCQVVRELVKYTNHFRILALSAT 247
++I LV DE H A+ ++ Y ++++ + RIL L+A+
Sbjct: 163 YLSLSDINLLVFDECHLAILDHPYREIMKLCENCPSCPRILGLTAS 208
Score = 41.2 bits (95), Expect = 0.011
Identities = 26/72 (36%), Positives = 38/72 (52%), Gaps = 5/72 (6%)
Query: 510 GHASGKSTKGFTQKE-----QLEVVKQFRDGGYNTLVSTCVGEEGLDIGEVDLIICFDSQ 564
GH GK+ Q E Q EV+++FR N L++T + EEG+DI + +L++ FD
Sbjct: 481 GHGIGKNQPRNKQMEAEFRKQEEVLRKFRAHETNLLIATSIVEEGVDIPKCNLVVRFDLP 540
Query: 565 KSPIRLVQRMGR 576
VQ GR
Sbjct: 541 TEYRSYVQSKGR 552
>gi|4885217 excision repair cross-complementing rodent repair
deficiency, complementation group 4 [Homo sapiens]
Length = 916
Score = 60.5 bits (145), Expect = 2e-08
Identities = 59/233 (25%), Positives = 103/233 (44%), Gaps = 19/233 (8%)
Query: 1813 QEGKGTCILVGGHEITSGLEVISSLRAIHGLQVEVCPLNGCDYIVSNRMVVERRSQSEML 1872
Q G I+V E S L + R G+ +E L DYI++ M VER+S S+++
Sbjct: 677 QNGTQQSIVVDMREFRSELPSLIHRR---GIDIEPVTLEVGDYILTPEMCVERKSISDLI 733
Query: 1873 NSVNKNKFIEQIQHLQSMFERICVIVEKDREKTGD-TSR--MFRRTKSYD----SLLTTL 1925
S+N + Q + ++R +++E D K TSR +F+ S D L TL
Sbjct: 734 GSLNNGRLYSQCISMSRYYKRPVLLIEFDPSKPFSLTSRGALFQEISSNDISSKLTLLTL 793
Query: 1926 IGAGIRILFSSCQEETADLLKELSLVEQRKNVGIHVPTVVNSN---KSEAL-----QFYL 1977
+RIL+ TA+L +EL + + + + +S +SE F L
Sbjct: 794 HFPRLRILWCPSPHATAELFEELKQSKPQPDAATALAITADSETLPESEKYNPGPQDFLL 853
Query: 1978 SIPNISYITALNMCHQFSSVKRMANSSLQEISMYAQVTHQKAEEIYRYIHYVF 2030
+P ++ ++ H ++ +A S E++ A+++Y +IH F
Sbjct: 854 KMPGVNAKNCRSLMHHVKNIAELAALSQDELTSILG-NAANAKQLYDFIHTSF 905
Score = 37.0 bits (84), Expect = 0.20
Identities = 46/233 (19%), Positives = 102/233 (43%), Gaps = 13/233 (5%)
Query: 90 PVRDYQLHISRAALFCNTLVCLPTGLGKTFIAAVVMYNFYRWF-PSGKVVFMAPTKPLVT 148
P+ +Y+ + L + LV GLG A ++Y+F + +V + T+P
Sbjct: 14 PLLEYERQLVLELLDTDGLVVCARGLG----ADRLLYHFLQLHCHPACLVLVLNTQPAEE 69
Query: 149 QQIEACYQVMGIPQSHMAE-MTGSTQASTRKEIWCSKRVLFLTPQVMVNDLSRGACPAAE 207
+ ++ G+ H+ +T +++R E++ V+F T +++V D P+
Sbjct: 70 EYFINQLKIEGV--EHLPRRVTNEITSNSRYEVYTQGGVIFATSRILVVDFLTDRIPSDL 127
Query: 208 IKCLVIDEAHKALGNYAYCQVVRELVKYTNHFRILALSATP---GSDIKAVQQVITNLLI 264
I +++ AH+ + + ++R + I A + + V++V+ NL +
Sbjct: 128 ITGILVYRAHRIIESCQEAFILRLFRQKNKRGFIKAFTDNAVAFDTGFCHVERVMRNLFV 187
Query: 265 GQIEL--RSEDSPDILTYSHERKVEKLIVPLGEELAAIQKTYIQILESFARSL 315
++ L R + + H+ +V ++ V + + AIQ + IL + + L
Sbjct: 188 RKLYLWPRFHVAVNSFLEQHKPEVVEIHVSMTPTMLAIQTAILDILNACLKEL 240
>gi|224593278 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 [Homo
sapiens]
Length = 796
Score = 54.3 bits (129), Expect = 1e-06
Identities = 47/215 (21%), Positives = 91/215 (42%), Gaps = 19/215 (8%)
Query: 480 MIFSSFRDSVQEIAEMLSQHQPIIRVMTFVGHASGKSTKGFTQKEQLEVVKQFRDGGYNT 539
++ +F D V + Q + ++ +G G+ +Q ++LE +++F+D +
Sbjct: 457 LLTRTFTDHVMLFTQTKKQAHRMHILLGLMGLQVGELHGNLSQTQRLEALRRFKDEQIDI 516
Query: 540 LVSTCVGEEGLDIGEVDLIICFDSQKSPIRLVQRMGRTGRK-RQGRIVIILSEGREERIY 598
LV+T V GLDI V +I F + V R+GRT R R GR V ++ E + +
Sbjct: 517 LVATDVAARGLDIEGVKTVINFTMPNTIKHYVHRVGRTARAGRAGRSVSLVGEDERKMLK 576
Query: 599 NQSQSNKRSIYKAISSNRQVLHFYQRSPRMVPDGINPKLHKMFITHGVYEPEKPSRNLQR 658
++ K + I +L F + +M D + V + E + +Q+
Sbjct: 577 EIVKAAKAPVKARILPQDVILKFRDKIEKMEKD-----------VYAVLQLEAEEKEMQQ 625
Query: 659 KSSIFSYRDGMRQSSL-------KKDWFLSEEEFK 686
+ + + + ++ WF ++EE K
Sbjct: 626 SEAQINTAKRLLEKGKEAVVQEPERSWFQTKEERK 660
Score = 40.0 bits (92), Expect = 0.023
Identities = 39/158 (24%), Positives = 72/158 (45%), Gaps = 12/158 (7%)
Query: 110 CLPTGLGKT--FIAAVVMYNFY--RWFPSGKVVFMAPTKPLVTQQIEACYQVMGIPQSHM 165
C TG GKT F V+ Y R P +V+ + PT+ L Q Q+
Sbjct: 261 CAATGTGKTAAFALPVLERLIYKPRQAPVTRVLVLVPTRELGIQVHSVTRQLAQFCNITT 320
Query: 166 AEMTGSTQASTRKE-IWCSKRVLFLTPQVMVNDLSRGACPA---AEIKCLVIDEAHKALG 221
G +++ + + +L TP +++ L CP+ + I+ L++DEA + L
Sbjct: 321 CLAVGGLDVKSQEAALRAAPDILIATPGRLIDHLHN--CPSFHLSSIEVLILDEADRMLD 378
Query: 222 NYAYCQVVRELVKYTNHFR-ILALSATPGSDIKAVQQV 258
Y + + ++E+++ +H R + SAT ++K + V
Sbjct: 379 EY-FEEQMKEIIRMCSHHRQTMLFSATMTDEVKDLASV 415
>gi|50659095 DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 [Homo
sapiens]
Length = 783
Score = 53.5 bits (127), Expect = 2e-06
Identities = 40/119 (33%), Positives = 58/119 (48%), Gaps = 13/119 (10%)
Query: 478 RVMIFSSFRDSVQEIAEMLSQHQPIIRVMTFVGHASGKSTKGFTQKEQLEV-VKQFRDGG 536
R +IF + QE LSQ+ I + +S G ++Q E+ +K FR+G
Sbjct: 440 RTIIFCETKKEAQE----LSQNSAIKQ--------DAQSLHGDIPQKQREITLKGFRNGS 487
Query: 537 YNTLVSTCVGEEGLDIGEVDLIICFDSQKSPIRLVQRMGRTGRKRQGRIVIILSEGREE 595
+ LV+T V GLDI EVDL+I K + R GRTGR + + I + +EE
Sbjct: 488 FGVLVATNVAARGLDIPEVDLVIQSSPPKDVESYIHRSGRTGRAGRTGVCICFYQHKEE 546
>gi|7661920 eukaryotic translation initiation factor 4A, isoform 3
[Homo sapiens]
Length = 411
Score = 50.1 bits (118), Expect = 2e-05
Identities = 27/76 (35%), Positives = 43/76 (56%)
Query: 522 QKEQLEVVKQFRDGGYNTLVSTCVGEEGLDIGEVDLIICFDSQKSPIRLVQRMGRTGRKR 581
QKE+ ++K+FR G L+ST V GLD+ +V LII +D + + R+GR+GR
Sbjct: 313 QKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYG 372
Query: 582 QGRIVIILSEGREERI 597
+ + I + + RI
Sbjct: 373 RKGVAINFVKNDDIRI 388
>gi|13129006 nucleolar protein GU2 [Homo sapiens]
Length = 737
Score = 49.7 bits (117), Expect = 3e-05
Identities = 38/119 (31%), Positives = 54/119 (45%), Gaps = 11/119 (9%)
Query: 476 ETRVMIFSSFRDSVQEIAEMLSQHQPIIRVMTFVGHASGKSTKGFTQKEQLEVVKQFRDG 535
E R +IF + +V E+A P I+ H Q ++ +K FR+G
Sbjct: 389 EGRAIIFCETKKNVTEMAM-----NPHIKQNAQCLHGD------IAQSQREITLKGFREG 437
Query: 536 GYNTLVSTCVGEEGLDIGEVDLIICFDSQKSPIRLVQRMGRTGRKRQGRIVIILSEGRE 594
+ LV+T V GLDI EVDL+I + + R GRTGR + I I + RE
Sbjct: 438 SFKVLVATNVAARGLDIPEVDLVIQSSPPQDVESYIHRSGRTGRAGRTGICICFYQPRE 496
>gi|38327634 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 [Homo
sapiens]
Length = 670
Score = 47.8 bits (112), Expect = 1e-04
Identities = 37/114 (32%), Positives = 53/114 (46%), Gaps = 12/114 (10%)
Query: 472 KKRDETRVMIFSSFRDSVQEIAEMLSQHQ-PIIRVMTFVGHASGKSTKGFTQKEQLEVVK 530
KK + ++M+F S SV+ E+L+ P++ + H K K T
Sbjct: 421 KKNRKKKLMVFFSSCMSVKYHYELLNYIDLPVLAI-----HGKQKQNKRTT------TFF 469
Query: 531 QFRDGGYNTLVSTCVGEEGLDIGEVDLIICFDSQKSPIRLVQRMGRTGRKRQGR 584
QF + TL+ T V GLDI EVD I+ +D P + R+GRT R GR
Sbjct: 470 QFCNADSGTLLCTDVAARGLDIPEVDWIVQYDPPDDPKEYIHRVGRTARGLNGR 523
Score = 31.6 bits (70), Expect = 8.3
Identities = 31/134 (23%), Positives = 64/134 (47%), Gaps = 8/134 (5%)
Query: 108 LVCLPTGLGKTF---IAAVVMYNFYRWFPSGK--VVFMAPTKPLVTQQIEACYQVMGIP- 161
L TG GKT I AV + R+ P V+ ++PT+ L Q ++M
Sbjct: 220 LAAAKTGSGKTLAFLIPAVELIVKLRFMPRNGTGVLILSPTRELAMQTFGVLKELMTHHV 279
Query: 162 QSHMAEMTGSTQASTRKEIWCSKRVLFLTPQVMVNDLSRG-ACPAAEIKCLVIDEAHKAL 220
++ M GS +++ +++ ++ TP +++ + ++CLVIDEA + L
Sbjct: 280 HTYGLIMGGSNRSAEAQKLGNGINIIVATPGRLLDHMQNTPGFMYKNLQCLVIDEADRIL 339
Query: 221 GNYAYCQVVRELVK 234
+ + + +++++K
Sbjct: 340 -DVGFEEELKQIIK 352
>gi|21071032 DEAD-box protein abstrakt [Homo sapiens]
Length = 622
Score = 47.0 bits (110), Expect = 2e-04
Identities = 37/143 (25%), Positives = 67/143 (46%), Gaps = 11/143 (7%)
Query: 479 VMIFSSFRDSVQEIAEMLSQHQPIIRVMTFVGHASGKSTKGFTQKEQLEVVKQFRDGGYN 538
V+IF+ + V I E L +++ + V GK Q+E+ + ++ FR+G +
Sbjct: 435 VLIFAEKKADVDAIHEYL-----LLKGVEAVAIHGGKD-----QEERTKAIEAFREGKKD 484
Query: 539 TLVSTCVGEEGLDIGEVDLIICFDSQKSPIRLVQRMGRTGRK-RQGRIVIILSEGREERI 597
LV+T V +GLD + +I +D + V R+GRTGR G +++ +E +
Sbjct: 485 VLVATDVASKGLDFPAIQHVINYDMPEEIENYVHRIGRTGRSGNTGIATTFINKACDESV 544
Query: 598 YNQSQSNKRSIYKAISSNRQVLH 620
++ + + QVLH
Sbjct: 545 LMDLKALLLEAKQKVPPVLQVLH 567
>gi|148762940 DVL-binding protein DAPLE [Homo sapiens]
Length = 2028
Score = 47.0 bits (110), Expect = 2e-04
Identities = 73/351 (20%), Positives = 143/351 (40%), Gaps = 28/351 (7%)
Query: 1412 LTSNESEDDEIFRRKVKRAKGNVLNSPEDQKNSEVDSPLHAVKKRRFPINRSELSSSDES 1471
L E E+ ++ R K + K L +K+ ++ +V + +S SSS ++
Sbjct: 723 LAQMERENQQLEREKEELRKNVDLLKALGKKSERLELSYQSVSAENLRLQQSLESSSHKT 782
Query: 1472 ENFPKPCSQLEDFKVCNGNARRGIKVPKRQSHLKHVARKFLDDEAELSEEDAEYVSSDEN 1531
+ +LE + +++ Q RK L+ E E+D + + E
Sbjct: 783 QTLESELGELEAERQALRRDLEALRLANAQLEGAEKDRKALEQEVAQLEKDKKLL---EK 839
Query: 1532 DESENEQDSSLLDFLNDETQLSQAINDSEMRAIYMKSLRSPMMNNKYKMIHKTHKNINIF 1591
+ Q L D + D++ + + E RA+ + R K K + K ++++
Sbjct: 840 EAKRLWQQVELKDAVLDDSTAKLSAVEKESRALDKELARCRDAAGKLKELEKDNRDLTKQ 899
Query: 1592 SQIPEQDETYLEDSFCVDEEESCKGQS-----SEEEVCVDFN---LITDDCFANSKKYKT 1643
+ + T L + +++ +S + S S+E V N L+ +D + KYK
Sbjct: 900 VTVHARTLTTLREDLVLEKLKSQQLSSELDKLSQELEKVGLNRELLLQEDDSGSDTKYKI 959
Query: 1644 ---RRAVMLKEMMEQNCAHSKKKLSRIILPDDSSEEENNVNDKRESNIAV---NPSTVKK 1697
R LK + K +I+L + EE+ ++N + ES + + T+++
Sbjct: 960 LEGRNESALKTTLAM-------KEEKIVLLEAQMEEKASLNRQLESELQMLKKECETLRQ 1012
Query: 1698 NK-QQDHCLNSV--PSGSSAQSKVRSTPRVNPLAKQSKQTSLNLKDTISEV 1745
N+ + H NS P+G +A S + P K++ L +KD E+
Sbjct: 1013 NQGEGQHLQNSFKHPAGKTAASH-QGKEAWGPGHKEATMELLRVKDRAIEL 1062
>gi|216548091 leucine zipper protein 1 [Homo sapiens]
Length = 1076
Score = 46.6 bits (109), Expect = 3e-04
Identities = 122/576 (21%), Positives = 212/576 (36%), Gaps = 96/576 (16%)
Query: 1330 LPVQKKVMSTPLSKSNTLNSFSKIRKEILKTPDSSKE--------KVNLQRFKEALNSTF 1381
L +Q KV+ S S+ L +R+ +L+ +E ++ ++ +E N T
Sbjct: 45 LDLQDKVIQAEGSNSSMLAEIEVLRQRVLRIEGKDEEIKRAEDLCRLMKEKLEEEENLTR 104
Query: 1382 DY-SEFS-----------LEKSKSSGPMYLHKSCHSVEDGQLLTSNESEDDEIFRRKVKR 1429
+ SE LE++ S + C S+ + + LT S + E+ R KVK
Sbjct: 105 ELKSEIERLQKRMAELEKLEEAFSRSKNDCTQLCLSLNEERNLTKKISSELEMLRVKVKE 164
Query: 1430 AKGNV--LNSPEDQKNSEVDS----PLHAVKKRRFPINRSELSSSDESENFPKPCSQ-LE 1482
+ + L+ E SE++ L V +R++ +N E E+E K +Q LE
Sbjct: 165 LESSEDRLDKTEQSLASELEKLKSLTLSFVSERKY-LNEKE----KENEKLIKELTQKLE 219
Query: 1483 DFKVCNGN-ARRGIKVPKRQSHLKHVARKFLDDEAELSEEDAEYV--------SSDENDE 1533
K N + R + + ++ L + + +Y+ + EN++
Sbjct: 220 QNKKMNRDYTRNASNLERNDLRIEDGISSTLPSKESRRKGGLDYLKQVENETRNKSENEK 279
Query: 1534 SENEQDSSLLDFLNDETQLSQAINDSEMRAIYMKSLRSPMMNNKYKMIHKTHKNINIFSQ 1593
+ N++D+ + D + +L I E +K ++S + + + + +KN + SQ
Sbjct: 280 NRNQEDNKVKDLNQEIEKLKTQIKHFESLEEELKKMKSKNNDLQDNYLSEQNKNKLLASQ 339
Query: 1594 IP------------EQDETYLEDSFCVD----EEESCKGQSSEEEVCVDF---------- 1627
+ E E ED+F E +G SE V
Sbjct: 340 LEEIKLQIKKQKELENGEVEGEDAFLSSKGRHERTKFRGHGSEASVSKHTARELSPQHKR 399
Query: 1628 -NLITDDCFANSKKYK-TRRAVMLKEMMEQNCAHSKKKLSRIILPDDSSEEENNVNDKRE 1685
L + N++ Y + R V + A K S + + DS +E + R
Sbjct: 400 ERLRNREFALNNENYSLSNRQVSSPSFTNRRAA----KASHMGVSTDSGTQETKKTEDRF 455
Query: 1686 SNIAVNPSTVKKNKQQDHCLNSVPSGSSAQSKVRSTPRVNPLAKQSKQTSLNLKDTISEV 1745
+ S KK+++Q L+ P + SK T LK + +
Sbjct: 456 VP-GSSQSEGKKSREQPSVLSRYPPAAQEHSKAWK-------GTSKPGTESGLKGKVEKT 507
Query: 1746 S-DFKPQNHNEVQSTTPPFTTVDSQKDCRKFPVPQKDGSALEDSS----TSGASCSKSRP 1800
+ F H V S P D D V K G L + S + + CSK+
Sbjct: 508 TRTFSDTTHGSVPS--DPLGRADKASDTSSETVFGKRGHVLGNGSQVTQAANSGCSKAIG 565
Query: 1801 HLAGTHTSLRLPQEGKGTCILVGGHEITSGLEVISS 1836
LA +S R EG L G + +GLE +S
Sbjct: 566 ALA---SSRRSSSEG-----LSKGKKAANGLEADNS 593
>gi|216548085 leucine zipper protein 1 [Homo sapiens]
Length = 1076
Score = 46.6 bits (109), Expect = 3e-04
Identities = 122/576 (21%), Positives = 212/576 (36%), Gaps = 96/576 (16%)
Query: 1330 LPVQKKVMSTPLSKSNTLNSFSKIRKEILKTPDSSKE--------KVNLQRFKEALNSTF 1381
L +Q KV+ S S+ L +R+ +L+ +E ++ ++ +E N T
Sbjct: 45 LDLQDKVIQAEGSNSSMLAEIEVLRQRVLRIEGKDEEIKRAEDLCRLMKEKLEEEENLTR 104
Query: 1382 DY-SEFS-----------LEKSKSSGPMYLHKSCHSVEDGQLLTSNESEDDEIFRRKVKR 1429
+ SE LE++ S + C S+ + + LT S + E+ R KVK
Sbjct: 105 ELKSEIERLQKRMAELEKLEEAFSRSKNDCTQLCLSLNEERNLTKKISSELEMLRVKVKE 164
Query: 1430 AKGNV--LNSPEDQKNSEVDS----PLHAVKKRRFPINRSELSSSDESENFPKPCSQ-LE 1482
+ + L+ E SE++ L V +R++ +N E E+E K +Q LE
Sbjct: 165 LESSEDRLDKTEQSLASELEKLKSLTLSFVSERKY-LNEKE----KENEKLIKELTQKLE 219
Query: 1483 DFKVCNGN-ARRGIKVPKRQSHLKHVARKFLDDEAELSEEDAEYV--------SSDENDE 1533
K N + R + + ++ L + + +Y+ + EN++
Sbjct: 220 QNKKMNRDYTRNASNLERNDLRIEDGISSTLPSKESRRKGGLDYLKQVENETRNKSENEK 279
Query: 1534 SENEQDSSLLDFLNDETQLSQAINDSEMRAIYMKSLRSPMMNNKYKMIHKTHKNINIFSQ 1593
+ N++D+ + D + +L I E +K ++S + + + + +KN + SQ
Sbjct: 280 NRNQEDNKVKDLNQEIEKLKTQIKHFESLEEELKKMKSKNNDLQDNYLSEQNKNKLLASQ 339
Query: 1594 IP------------EQDETYLEDSFCVD----EEESCKGQSSEEEVCVDF---------- 1627
+ E E ED+F E +G SE V
Sbjct: 340 LEEIKLQIKKQKELENGEVEGEDAFLSSKGRHERTKFRGHGSEASVSKHTARELSPQHKR 399
Query: 1628 -NLITDDCFANSKKYK-TRRAVMLKEMMEQNCAHSKKKLSRIILPDDSSEEENNVNDKRE 1685
L + N++ Y + R V + A K S + + DS +E + R
Sbjct: 400 ERLRNREFALNNENYSLSNRQVSSPSFTNRRAA----KASHMGVSTDSGTQETKKTEDRF 455
Query: 1686 SNIAVNPSTVKKNKQQDHCLNSVPSGSSAQSKVRSTPRVNPLAKQSKQTSLNLKDTISEV 1745
+ S KK+++Q L+ P + SK T LK + +
Sbjct: 456 VP-GSSQSEGKKSREQPSVLSRYPPAAQEHSKAWK-------GTSKPGTESGLKGKVEKT 507
Query: 1746 S-DFKPQNHNEVQSTTPPFTTVDSQKDCRKFPVPQKDGSALEDSS----TSGASCSKSRP 1800
+ F H V S P D D V K G L + S + + CSK+
Sbjct: 508 TRTFSDTTHGSVPS--DPLGRADKASDTSSETVFGKRGHVLGNGSQVTQAANSGCSKAIG 565
Query: 1801 HLAGTHTSLRLPQEGKGTCILVGGHEITSGLEVISS 1836
LA +S R EG L G + +GLE +S
Sbjct: 566 ALA---SSRRSSSEG-----LSKGKKAANGLEADNS 593
>gi|217330641 IWS1 homolog [Homo sapiens]
Length = 819
Score = 46.6 bits (109), Expect = 3e-04
Identities = 93/465 (20%), Positives = 181/465 (38%), Gaps = 76/465 (16%)
Query: 1299 NEDMQNPNYVHLPLSAAKNEELLSPGYSQFSLPVQKKVMSTPLSKSNTLNSFSKI--RKE 1356
+ D ++ P S ++NE++ G S +K+ + LN + ++
Sbjct: 92 DSDSESEERAEPPASDSENEDVNQHG-SDSESEETRKLPGSDSENEELLNGHASDSENED 150
Query: 1357 ILKTPDSSKEKVNLQRFKEALNSTFDYSEFSLEKSKSSGPMYLHKSCHSVEDGQLLTSNE 1416
+ K P S E LQ+ + + T D + + S+S P S E+ ++
Sbjct: 151 VGKHPASDSEIEELQKSPASDSETEDALKPQISDSESEEPPRHQASDSENEEPPKPRMSD 210
Query: 1417 SEDDEIFRRKVKRAKGNVLNSPEDQKNSEVDSPLHAVKKRRFPINRSE-----LSSSDES 1471
SE +E+ + +V ++ S E ++ DS + K R + SE +S E+
Sbjct: 211 SESEELPKPQVSDSE-----SEEPPRHQASDSENEELPKPRISDSESEDPPRHQASDSEN 265
Query: 1472 ENFPKPC---SQLEDFKVCNGNARRGIKVPKRQSHLKHVARKFLDDEAELSEEDAEYVSS 1528
E PKP S+ ED + ++PK + +S+ ++E
Sbjct: 266 EELPKPRISDSESEDPPRNQASDSENEELPKPR----------------VSDSESEGPQK 309
Query: 1529 DENDESENEQDSSLLDFLNDETQLSQAINDSEMRAIYMKSLRSPMMNNKYKMIHKTHKNI 1588
+SE E S Q ++ +DS+ K + M N+ + +H +
Sbjct: 310 GPASDSETEDASR-------HKQKPESDDDSDREN---KGEDTEMQNDSFHS--DSHMDR 357
Query: 1589 NIFSQIPEQDETYLEDSFCVDEEESCKGQSSEEEVCVDFNLITDDCFANSKKYKTRRAVM 1648
F ++E + + DE+E + EEE K R+A +
Sbjct: 358 KKFHSSDSEEEEHKKQKMDSDEDE----KEGEEE-----------------KVAKRKAAV 396
Query: 1649 LKEMMEQNCAHSKKKLSRIILPDDSSEEE--NNVNDKRESNIAVNPS-------TVKKNK 1699
L + ++ A +KK SR++ D S+ + ++ + KRE IA + + KKN+
Sbjct: 397 LSDSEDEEKASAKK--SRVVSDADDSDSDAVSDKSGKREKTIASDSEEEAGKELSDKKNE 454
Query: 1700 QQDHCLNSVPSGSSAQSKVRSTPRVNPLAKQSKQTSLNLKDTISE 1744
++D + SG+ ++ + + ++ + T N +D E
Sbjct: 455 EKDLFGSDSESGNEEENLIADIFGESGDEEEEEFTGFNQEDLEEE 499
Score = 33.9 bits (76), Expect = 1.7
Identities = 62/295 (21%), Positives = 119/295 (40%), Gaps = 38/295 (12%)
Query: 1282 PRDHSKNFTSGTVIIPSNEDMQNPNYVHLPLSAAKNEELLSPGYSQFSLPVQKKVMSTPL 1341
PR + + + + P D ++ + S ++NEEL P S +K P
Sbjct: 256 PRHQASDSENEELPKPRISDSESEDPPRNQASDSENEELPKPRVSDSESEGPQK---GPA 312
Query: 1342 SKSNTLNSFSKIRKEILKTPDSSKEKVNLQRFKEALNSTFDYSEFSLEKSKSSGPMYLHK 1401
S S T ++ S+ +++ DS +E N E N +F +S+ +++ K H
Sbjct: 313 SDSETEDA-SRHKQKPESDDDSDRE--NKGEDTEMQNDSF-HSDSHMDRKK------FHS 362
Query: 1402 SCHSVEDGQLLTSNESEDD-EIFRRKVKRAKGNVLNSPEDQKNSEV----------DSPL 1450
S E+ + + ED+ E KV + K VL+ ED++ + DS
Sbjct: 363 SDSEEEEHKKQKMDSDEDEKEGEEEKVAKRKAAVLSDSEDEEKASAKKSRVVSDADDSDS 422
Query: 1451 HAVKKRRFPINRSELSSSDESENFPKPCSQLEDFKVCNGNARRGIKVPKRQSHLKHVARK 1510
AV + ++ S S+E + E+ + ++ G + ++ + + +
Sbjct: 423 DAVSDKSGKREKTIASDSEEEAGKELSDKKNEEKDLFGSDSESG---NEEENLIADIFGE 479
Query: 1511 FLDDEAE---------LSEEDAE--YVSSDENDESENEQDSSLLDFLNDETQLSQ 1554
D+E E L EE E ++++D +N + +DFL+D + Q
Sbjct: 480 SGDEEEEEFTGFNQEDLEEEKGETQVKEAEDSDSDDNIKRGKHMDFLSDFEMMLQ 534
>gi|87196351 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3 [Homo
sapiens]
Length = 662
Score = 46.2 bits (108), Expect = 3e-04
Identities = 25/59 (42%), Positives = 33/59 (55%)
Query: 521 TQKEQLEVVKQFRDGGYNTLVSTCVGEEGLDIGEVDLIICFDSQKSPIRLVQRMGRTGR 579
+Q+++ E + QFR G LV+T V GLDI V +I FD V R+GRTGR
Sbjct: 476 SQRDREEALHQFRSGKSPILVATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGR 534
>gi|169881239 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
[Homo sapiens]
Length = 660
Score = 45.8 bits (107), Expect = 4e-04
Identities = 25/59 (42%), Positives = 33/59 (55%)
Query: 521 TQKEQLEVVKQFRDGGYNTLVSTCVGEEGLDIGEVDLIICFDSQKSPIRLVQRMGRTGR 579
+Q+++ E + QFR G LV+T V GLDI V +I FD V R+GRTGR
Sbjct: 474 SQRDREEALHQFRSGKSPILVATAVAARGLDISNVRHVINFDLPSDIEEYVHRIGRTGR 532
>gi|13514809 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
[Homo sapiens]
Length = 660
Score = 45.8 bits (107), Expect = 4e-04
Identities = 25/59 (42%), Positives = 33/59 (55%)
Query: 521 TQKEQLEVVKQFRDGGYNTLVSTCVGEEGLDIGEVDLIICFDSQKSPIRLVQRMGRTGR 579
+Q+++ E + QFR G LV+T V GLDI V +I FD V R+GRTGR
Sbjct: 474 SQRDREEALHQFRSGKSPILVATAVAARGLDISNVRHVINFDLPSDIEEYVHRIGRTGR 532
>gi|76880486 activating signal cointegrator 1 complex subunit 3
isoform a [Homo sapiens]
Length = 2202
Score = 45.4 bits (106), Expect = 6e-04
Identities = 46/159 (28%), Positives = 76/159 (47%), Gaps = 19/159 (11%)
Query: 106 NTLVCLPTGLGKTFIAAV-VMYNFYRWFPSG-------KVVFMAPTKPLVTQQIEACYQV 157
N L+C PTG GKT IA + V++ + F G K+V++AP K L + + +
Sbjct: 494 NMLICAPTGAGKTNIAMLTVLHEIRQHFQQGVIKKNEFKIVYVAPMKALAAEMTDYFSRR 553
Query: 158 MGIPQSHMAEMTGSTQASTRKEIWCSKRVLFLTPQV--MVNDLSRGACPAAEI-KCLVID 214
+ + E+TG Q S + EI ++L TP+ +V S G ++I + L++D
Sbjct: 554 LEPLGIIVKELTGDMQLS-KSEI-LRTQMLVTTPEKWDVVTRKSVGDVALSQIVRLLILD 611
Query: 215 EAH------KALGNYAYCQVVRELVKYTNHFRILALSAT 247
E H + + +R++ + RIL LSAT
Sbjct: 612 EVHLLHEDRGPVLESIVARTLRQVESTQSMIRILGLSAT 650
Score = 44.7 bits (104), Expect = 0.001
Identities = 18/48 (37%), Positives = 31/48 (64%)
Query: 105 CNTLVCLPTGLGKTFIAAVVMYNFYRWFPSGKVVFMAPTKPLVTQQIE 152
CN L+ PTG GKT A + ++ + +P+ K V++AP K LV ++++
Sbjct: 1343 CNVLLGAPTGSGKTVAAELAIFRVFNKYPTSKAVYIAPLKALVRERMD 1390
>gi|188035877 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 [Homo
sapiens]
Length = 619
Score = 45.4 bits (106), Expect = 6e-04
Identities = 28/87 (32%), Positives = 43/87 (49%), Gaps = 3/87 (3%)
Query: 515 KSTKGFTQKEQLE---VVKQFRDGGYNTLVSTCVGEEGLDIGEVDLIICFDSQKSPIRLV 571
KS ++K Q+E ++K +G Y +VST V GLD+ V L++ FD S V
Sbjct: 471 KSISIHSEKSQIERKNILKGLLEGDYEVVVSTGVLGRGLDLISVRLVVNFDMPSSMDEYV 530
Query: 572 QRMGRTGRKRQGRIVIILSEGREERIY 598
++GR GR Q I +R++
Sbjct: 531 HQIGRVGRLGQNGTAITFINNNSKRLF 557
Score = 38.1 bits (87), Expect = 0.089
Identities = 58/269 (21%), Positives = 112/269 (41%), Gaps = 21/269 (7%)
Query: 108 LVCLPTGLGKT--FIAAVVMYNFYRWFPSGKVVFMAPTKPLVTQQIEACYQVM-GIPQSH 164
L TG GKT F+ V+M + + + + PT+ L Q ++M G+P+
Sbjct: 244 LASADTGSGKTAAFLLPVIMRALFE-SKTPSALILTPTRELAIQIERQAKELMSGLPRMK 302
Query: 165 MAEMTGSTQASTRK-EIWCSKRVLFLTPQVMVNDLSRGACPAAEIKCLVIDEAHKALGNY 223
+ G + + +V+ TP +++ + + + +K +V+DEA L
Sbjct: 303 TVLLVGGLPLPPQLYRLQQHVKVIIATPGRLLDIIKQSSVELCGVKIVVVDEADTMLKMG 362
Query: 224 AYCQVVRELVKYTNHFRILALSAT-PGSDIKAVQQVITN---LLIGQIELRSEDSPDILT 279
QV+ L N + + +SAT P S + Q++ N ++ G+ L + I+
Sbjct: 363 FQQQVLDILENIPNDCQTILVSATIPTSIEQLASQLLHNPVRIITGEKNLPCANVRQIIL 422
Query: 280 YSHE-RKVEKLIVPLGEELAAIQKTYIQILESFARSLIQRNVLMRRDIPNLTKYQIILAR 338
+ + K +KL L ++ + + L+ V + I L I +
Sbjct: 423 WVEDPAKKKKLFEILNDKKLFKPPVLVFVDCKLGADLLSEAV---QKITGLKSISIHSEK 479
Query: 339 DQF-RKNPSPNIVGIQQGIIEGEFAICIS 366
Q RKN I +G++EG++ + +S
Sbjct: 480 SQIERKN-------ILKGLLEGDYEVVVS 501
>gi|154759257 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51 [Homo
sapiens]
Length = 666
Score = 45.4 bits (106), Expect = 6e-04
Identities = 30/121 (24%), Positives = 60/121 (49%), Gaps = 10/121 (8%)
Query: 477 TRVMIFSSFRDSVQEIAEMLSQHQPIIRVMTFVGHASGKSTKGFTQKEQLEVVKQFRDGG 536
+RV+ F++ R++ H+ + V F G + + + ++ ++KQF G
Sbjct: 505 SRVLCFTNSREN---------SHRLFLLVQAFGGVDVAEFSSRYGPGQRRMILKQFEQGK 555
Query: 537 YNTLVSTCVGEEGLDIGEVDLIICFDSQKSPIRLVQRMGRTGRK-RQGRIVIILSEGREE 595
L+ST G+D+ V+L++ +D+ + V R+GRT R + G+ +L + +E
Sbjct: 556 IQLLISTDATARGIDVQGVELVVNYDAPQYLRTYVHRVGRTARAGKTGQAFTLLLKVQER 615
Query: 596 R 596
R
Sbjct: 616 R 616
>gi|209862869 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 3
[Homo sapiens]
Length = 724
Score = 44.3 bits (103), Expect = 0.001
Identities = 33/104 (31%), Positives = 47/104 (45%), Gaps = 10/104 (9%)
Query: 476 ETRVMIFSSFRDSVQEIAEMLSQHQPIIRVMTFVGHASGKSTKGFTQKEQLEVVKQFRDG 535
+ R M+F + IA L Q ++ T H + Q+E+ + + FR G
Sbjct: 540 DERTMVFVETKKKADFIATFLCQE----KISTTSIHGDRE------QREREQALGDFRFG 589
Query: 536 GYNTLVSTCVGEEGLDIGEVDLIICFDSQKSPIRLVQRMGRTGR 579
LV+T V GLDI V +I FD + V R+GRTGR
Sbjct: 590 KCPVLVATSVAARGLDIENVQHVINFDLPSTIDEYVHRIGRTGR 633
Score = 35.4 bits (80), Expect = 0.58
Identities = 40/167 (23%), Positives = 69/167 (41%), Gaps = 17/167 (10%)
Query: 65 ERQLCLENGGFCTSAGALWIYPTNCPVRDYQLHISRAALFCNTLVCLPTGLGKT--FIAA 122
E LC AG Y PV+ Y + I A + + C TG GKT F+
Sbjct: 292 EANLCQTLNNNIAKAG----YTKLTPVQKYSIPIILAGR--DLMACAQTGSGKTAAFLLP 345
Query: 123 VVMYNFYRWFPSGKV--------VFMAPTKPLVTQ-QIEACYQVMGIPQSHMAEMTGSTQ 173
++ + + + + + +APT+ LV Q +EA G + G+
Sbjct: 346 ILAHMMHDGITASRFKELQEPECIIVAPTRELVNQIYLEARKFSFGTCVRAVVIYGGTQL 405
Query: 174 ASTRKEIWCSKRVLFLTPQVMVNDLSRGACPAAEIKCLVIDEAHKAL 220
+ ++I +L TP +++ + + +IK LV+DEA + L
Sbjct: 406 GHSIRQIVQGCNILCATPGRLMDIIGKEKIGLKQIKYLVLDEADRML 452
>gi|13518015 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 1
[Homo sapiens]
Length = 724
Score = 44.3 bits (103), Expect = 0.001
Identities = 33/104 (31%), Positives = 47/104 (45%), Gaps = 10/104 (9%)
Query: 476 ETRVMIFSSFRDSVQEIAEMLSQHQPIIRVMTFVGHASGKSTKGFTQKEQLEVVKQFRDG 535
+ R M+F + IA L Q ++ T H + Q+E+ + + FR G
Sbjct: 540 DERTMVFVETKKKADFIATFLCQE----KISTTSIHGDRE------QREREQALGDFRFG 589
Query: 536 GYNTLVSTCVGEEGLDIGEVDLIICFDSQKSPIRLVQRMGRTGR 579
LV+T V GLDI V +I FD + V R+GRTGR
Sbjct: 590 KCPVLVATSVAARGLDIENVQHVINFDLPSTIDEYVHRIGRTGR 633
Score = 35.4 bits (80), Expect = 0.58
Identities = 40/167 (23%), Positives = 69/167 (41%), Gaps = 17/167 (10%)
Query: 65 ERQLCLENGGFCTSAGALWIYPTNCPVRDYQLHISRAALFCNTLVCLPTGLGKT--FIAA 122
E LC AG Y PV+ Y + I A + + C TG GKT F+
Sbjct: 292 EANLCQTLNNNIAKAG----YTKLTPVQKYSIPIILAGR--DLMACAQTGSGKTAAFLLP 345
Query: 123 VVMYNFYRWFPSGKV--------VFMAPTKPLVTQ-QIEACYQVMGIPQSHMAEMTGSTQ 173
++ + + + + + +APT+ LV Q +EA G + G+
Sbjct: 346 ILAHMMHDGITASRFKELQEPECIIVAPTRELVNQIYLEARKFSFGTCVRAVVIYGGTQL 405
Query: 174 ASTRKEIWCSKRVLFLTPQVMVNDLSRGACPAAEIKCLVIDEAHKAL 220
+ ++I +L TP +++ + + +IK LV+DEA + L
Sbjct: 406 GHSIRQIVQGCNILCATPGRLMDIIGKEKIGLKQIKYLVLDEADRML 452
>gi|216548263 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 2
[Homo sapiens]
Length = 690
Score = 44.3 bits (103), Expect = 0.001
Identities = 33/104 (31%), Positives = 47/104 (45%), Gaps = 10/104 (9%)
Query: 476 ETRVMIFSSFRDSVQEIAEMLSQHQPIIRVMTFVGHASGKSTKGFTQKEQLEVVKQFRDG 535
+ R M+F + IA L Q ++ T H + Q+E+ + + FR G
Sbjct: 506 DERTMVFVETKKKADFIATFLCQE----KISTTSIHGDRE------QREREQALGDFRFG 555
Query: 536 GYNTLVSTCVGEEGLDIGEVDLIICFDSQKSPIRLVQRMGRTGR 579
LV+T V GLDI V +I FD + V R+GRTGR
Sbjct: 556 KCPVLVATSVAARGLDIENVQHVINFDLPSTIDEYVHRIGRTGR 599
Score = 35.4 bits (80), Expect = 0.58
Identities = 40/167 (23%), Positives = 69/167 (41%), Gaps = 17/167 (10%)
Query: 65 ERQLCLENGGFCTSAGALWIYPTNCPVRDYQLHISRAALFCNTLVCLPTGLGKT--FIAA 122
E LC AG Y PV+ Y + I A + + C TG GKT F+
Sbjct: 258 EANLCQTLNNNIAKAG----YTKLTPVQKYSIPIILAGR--DLMACAQTGSGKTAAFLLP 311
Query: 123 VVMYNFYRWFPSGKV--------VFMAPTKPLVTQ-QIEACYQVMGIPQSHMAEMTGSTQ 173
++ + + + + + +APT+ LV Q +EA G + G+
Sbjct: 312 ILAHMMHDGITASRFKELQEPECIIVAPTRELVNQIYLEARKFSFGTCVRAVVIYGGTQL 371
Query: 174 ASTRKEIWCSKRVLFLTPQVMVNDLSRGACPAAEIKCLVIDEAHKAL 220
+ ++I +L TP +++ + + +IK LV+DEA + L
Sbjct: 372 GHSIRQIVQGCNILCATPGRLMDIIGKEKIGLKQIKYLVLDEADRML 418
>gi|31542656 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 [Homo
sapiens]
Length = 483
Score = 44.3 bits (103), Expect = 0.001
Identities = 23/71 (32%), Positives = 41/71 (57%), Gaps = 1/71 (1%)
Query: 522 QKEQLEVVKQFRDGGYNTLVSTCVGEEGLDIGEVDLIICFDSQKSPIRLVQRMGRTGRK- 580
QKE+ + +F+ Y L++T V GLDI V ++I ++ P + R+GRT R
Sbjct: 284 QKERFAALAKFKSSIYRILIATDVASRGLDIPTVQVVINHNTPGLPKIYIHRVGRTARAG 343
Query: 581 RQGRIVIILSE 591
RQG+ + ++++
Sbjct: 344 RQGQAITLVTQ 354
>gi|38788333 remodeling and spacing factor 1 [Homo sapiens]
Length = 1441
Score = 43.9 bits (102), Expect = 0.002
Identities = 111/499 (22%), Positives = 188/499 (37%), Gaps = 88/499 (17%)
Query: 1318 EELLSPGYSQFSLPVQKKVMSTPLSKSNTLNSFS-KIRKEILKTPDSSKEKVNLQRFKEA 1376
E ++ P FS ++K + SK+N L S + RK I D E ++ EA
Sbjct: 979 ENIIPPQEPDFSEDQEEKKKDSKKSKANLLERRSTRTRKCISYRFDEFDEAID-----EA 1033
Query: 1377 LNSTF---DYSEFSLEKSKSSGPMYLHKSCHSVEDGQLLTSNESEDDEIFRRKVKRAKGN 1433
+ D K S+ + K ++ D + + + RRK KR + N
Sbjct: 1034 IEDDIKEADGGGVGRGKDISTITGHRGKDISTILDEERKENKRPQRAAAARRK-KRRRLN 1092
Query: 1434 VLNSPE--DQKNSEVDSPLHAVKKRRFPINRSELSSSDESENFPKPCSQLEDFKVCNGNA 1491
L+S D++ SE + + + F ++ + DESE P P + D C+
Sbjct: 1093 DLDSDSNLDEEESEDEFKISDGSQDEFVVSDE---NPDESEEDP-PSNDDSDTDFCSRRL 1148
Query: 1492 RRGIKVPKRQSHLKHVARKFLDDEAELSEEDAEYVSSDENDESENEQDSSLLDFLNDETQ 1551
RR P RQS + + RK +Y DE +ESE S DF +D
Sbjct: 1149 RRHPSRPMRQS--RRLRRK---------TPKKKYSDDDEEEESEENSRDSESDFSDD--- 1194
Query: 1552 LSQAINDSEMRAIYMKSLRSPMMNNKYKMIHK---THKNINIFSQIPEQDETYLEDSFCV 1608
+D + +S R+ YK + + K++ +I + L S
Sbjct: 1195 ----FSDDFVETRRRRSRRNQKRQINYKEDSESDGSQKSLRRGKEIRRVHKRRLSSS--- 1247
Query: 1609 DEEESCKGQSSEEEVCVDFNLITDDCFANSKKYKTRRAVMLKEMMEQNCAHSKKKLSRII 1668
+ EES ++SE+ D+ SK+ +R E E +
Sbjct: 1248 ESEESYLSKNSED----------DELAKESKRSVRKRGRSTDEYSEAD------------ 1285
Query: 1669 LPDDSSEEENNVNDKRESNIAVNPSTVKKNKQQDHCLNSVPSGSSAQSKVRSTPRVNPLA 1728
++ EEE + KR I + +++ C N+ G + Q S PRV P
Sbjct: 1286 --EEEEEEEGKPSRKRLHRI--------ETDEEESCDNA--HGDANQPARDSQPRVLPSE 1333
Query: 1729 KQSKQTSLNLKDTISEVSDFKPQNHNEVQSTTPPFTTVDSQKDCRKFP---------VPQ 1779
++S + ++ E DF +N +V S ++ VD + P P
Sbjct: 1334 QESTKKPYRIES--DEEEDF--ENVGKVGSPL-DYSLVDLPSTNGQSPGKAIENLIGKPT 1388
Query: 1780 KDGSALEDSSTSGASCSKS 1798
+ +D+ST+ AS + +
Sbjct: 1389 EKSQTPKDNSTASASLASN 1407
>gi|149944526 additional sex combs like 3 [Homo sapiens]
Length = 2248
Score = 43.9 bits (102), Expect = 0.002
Identities = 80/333 (24%), Positives = 129/333 (38%), Gaps = 46/333 (13%)
Query: 1108 QNLVGENNHDVDNSDLPVLSTD---QDESLLLFEDVNTEFDDVSLSPLNSKSESLPVSDK 1164
+N EN H S++ +ST + SL+ + +E VS PL S E+ P+SD
Sbjct: 665 RNSTDENFHASLMSEISPISTSPEISEASLMSNLPLTSEASPVSNLPLTS--ETSPMSDL 722
Query: 1165 TAISETPLVSQFLISDELLLDNNSELQDQITRDANSFKSRDQRGVQEEKVKNHEDIFDCS 1224
SET VS L++ E ++ L + + +NS + Q + E+
Sbjct: 723 PLTSETSSVSSMLLTSETTFVSSLPLPSETSPISNSSINERMAHQQRKSPSVSEEPLSPQ 782
Query: 1225 RDLFSVTFDLGFCSPDSDDEILEHTSDSNRPLDDLYGRYLEIKEISDANYVSNQALIPRD 1284
+D S T P ++ + + SN P I ++ ++ +A D
Sbjct: 783 KDESSAT-----AKPLGENLTSQQKNLSNTP----------EPIIMSSSSIAPEAFPSED 827
Query: 1285 -HSKNFTSGTVIIPSNEDMQNPNYVHLPLSAAKNEELLSPGYSQFSLPVQKKVMSTPL-- 1341
H+K + T S+ D + P +P A + E++ +KKV+ +PL
Sbjct: 828 LHNKTLSQQT--CKSHVDTEKPYPASIPELA--STEMIKVKNHSVLQRTEKKVLPSPLEL 883
Query: 1342 --------SKSNTLNSFSKIRKEILKTPDSSKEKVNLQRFKEALNSTFDYSEFSLEKSKS 1393
+K N L S K+ + + D + + ST E S SKS
Sbjct: 884 SVFSEGTDNKGNELPSAKLQDKQYISSVDKAPFSEGSRNKTHKQGSTQSRLETS-HTSKS 942
Query: 1394 SGPMYLHKSCHSVEDGQLLTSNESEDDEIFRRK 1426
S P KS + NES D EI +RK
Sbjct: 943 SEP---SKSPDGIR-------NESRDSEISKRK 965
>gi|45446747 DEAD box polypeptide 42 protein [Homo sapiens]
Length = 938
Score = 43.5 bits (101), Expect = 0.002
Identities = 29/101 (28%), Positives = 46/101 (45%), Gaps = 10/101 (9%)
Query: 479 VMIFSSFRDSVQEIAEMLSQHQPIIRVMTFVGHASGKSTKGFTQKEQLEVVKQFRDGGYN 538
V++F + + + +E+A L Q GH G Q E+ +V+ F+
Sbjct: 501 VLLFVTKKANAEELANNLKQE----------GHNLGLLHGDMDQSERNKVISDFKKKDIP 550
Query: 539 TLVSTCVGEEGLDIGEVDLIICFDSQKSPIRLVQRMGRTGR 579
LV+T V GLDI + +I +D + R+GRTGR
Sbjct: 551 VLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGR 591
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.130 0.370
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 75,812,179
Number of Sequences: 37866
Number of extensions: 3498262
Number of successful extensions: 10888
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 62
Number of HSP's successfully gapped in prelim test: 180
Number of HSP's that attempted gapping in prelim test: 10343
Number of HSP's gapped (non-prelim): 750
length of query: 2048
length of database: 18,247,518
effective HSP length: 118
effective length of query: 1930
effective length of database: 13,779,330
effective search space: 26594106900
effective search space used: 26594106900
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.