Guide to the Human Genome
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Search of human proteins with 74319833

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|74319833 ubiquitin specific protease 9, Y-linked [Homo
sapiens]
         (2555 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|74319833 ubiquitin specific protease 9, Y-linked [Homo sapiens]   5204   0.0  
gi|145309311 ubiquitin specific protease 9, X-linked isoform 4 [...  4808   0.0  
gi|145309309 ubiquitin specific protease 9, X-linked isoform 3 [...  4797   0.0  
gi|149192845 ubiquitin specific protease 24 [Homo sapiens]            942   0.0  
gi|110347427 ubiquitin specific protease 34 [Homo sapiens]            256   2e-67
gi|52630449 ubiquitin specific protease 48 isoform a [Homo sapiens]   140   2e-32
gi|76257392 ubiquitin specific protease 48 isoform b [Homo sapiens]   140   2e-32
gi|71774197 ubiquitin specific protease 47 [Homo sapiens]             138   8e-32
gi|150378533 ubiquitin specific peptidase 7 [Homo sapiens]            118   7e-26
gi|41055953 ubiquitin thioesterase 40 [Homo sapiens]                  114   9e-25
gi|239742282 PREDICTED: hypothetical protein XP_002342474 [Homo ...    91   1e-17
gi|197116355 ubiquitin specific peptidase 46 isoform 2 [Homo sap...    90   2e-17
gi|31377709 ubiquitin specific peptidase 46 isoform 1 [Homo sapi...    90   2e-17
gi|153792150 deubiquitinating enzyme 3 [Homo sapiens]                  90   3e-17
gi|190684694 ubiquitin specific peptidase 8 [Homo sapiens]             89   4e-17
gi|190684692 ubiquitin specific peptidase 8 [Homo sapiens]             89   4e-17
gi|190684690 ubiquitin specific peptidase 8 [Homo sapiens]             89   4e-17
gi|122114651 ubiquitin specific peptidase 36 [Homo sapiens]            89   7e-17
gi|239758075 PREDICTED: similar to deubiquitinating enzyme DUB1 ...    87   2e-16
gi|169172882 PREDICTED: Ubiquitin carboxyl-terminal hydrolase 17...    87   2e-16
gi|239742297 PREDICTED: hypothetical protein XP_002342480 [Homo ...    87   2e-16
gi|239742287 PREDICTED: hypothetical protein XP_002342475 [Homo ...    87   2e-16
gi|32698815 ubiquitin thiolesterase 12 [Homo sapiens]                  87   2e-16
gi|157785653 ubiquitin specific peptidase 17 [Homo sapiens]            87   2e-16
gi|169217654 PREDICTED: similar to deubiquitinating enzyme DUB1 ...    87   3e-16
gi|113415490 PREDICTED: similar to deubiquitinating enzyme 1 [Ho...    86   4e-16
gi|113415488 PREDICTED: similar to deubiquitinating enzyme 1 [Ho...    86   4e-16
gi|113415486 PREDICTED: similar to deubiquitinating enzyme 1 [Ho...    86   4e-16
gi|113415484 PREDICTED: similar to deubiquitinating enzyme 1 [Ho...    86   4e-16
gi|113415480 PREDICTED: similar to deubiquitinating enzyme 1 [Ho...    86   4e-16

>gi|74319833 ubiquitin specific protease 9, Y-linked [Homo sapiens]
          Length = 2555

 Score = 5204 bits (13498), Expect = 0.0
 Identities = 2555/2555 (100%), Positives = 2555/2555 (100%)

Query: 1    MTAITHGSPVGGNDSQGQVLDGQSQHLFQQNQTSSPDSSNENSVATPPPEEQGQGDAPPQ 60
            MTAITHGSPVGGNDSQGQVLDGQSQHLFQQNQTSSPDSSNENSVATPPPEEQGQGDAPPQ
Sbjct: 1    MTAITHGSPVGGNDSQGQVLDGQSQHLFQQNQTSSPDSSNENSVATPPPEEQGQGDAPPQ 60

Query: 61   HEDEEPAFPHTELANLDDMINRPRWVVPVLPKGELEVLLEAAIDLSVKGLDVKSEACQRF 120
            HEDEEPAFPHTELANLDDMINRPRWVVPVLPKGELEVLLEAAIDLSVKGLDVKSEACQRF
Sbjct: 61   HEDEEPAFPHTELANLDDMINRPRWVVPVLPKGELEVLLEAAIDLSVKGLDVKSEACQRF 120

Query: 121  FRDGLTISFTKILMDEAVSGWKFEIHRCIINNTHRLVELCVAKLSQDWFPLLELLAMALN 180
            FRDGLTISFTKILMDEAVSGWKFEIHRCIINNTHRLVELCVAKLSQDWFPLLELLAMALN
Sbjct: 121  FRDGLTISFTKILMDEAVSGWKFEIHRCIINNTHRLVELCVAKLSQDWFPLLELLAMALN 180

Query: 181  PHCKFHIYNGTRPCELISSNAQLPEDELFARSSDPRSPKGWLVDLINKFGTLNGFQILHD 240
            PHCKFHIYNGTRPCELISSNAQLPEDELFARSSDPRSPKGWLVDLINKFGTLNGFQILHD
Sbjct: 181  PHCKFHIYNGTRPCELISSNAQLPEDELFARSSDPRSPKGWLVDLINKFGTLNGFQILHD 240

Query: 241  RFFNGSALNIQIIAALIKPFGQCYEFLSQHTLKKYFIPVIEIVPHLLENLTDEELKKEAK 300
            RFFNGSALNIQIIAALIKPFGQCYEFLSQHTLKKYFIPVIEIVPHLLENLTDEELKKEAK
Sbjct: 241  RFFNGSALNIQIIAALIKPFGQCYEFLSQHTLKKYFIPVIEIVPHLLENLTDEELKKEAK 300

Query: 301  NEAKNDALSMIIKSLKNLASRISGQDETIKNLEIFRLKMILRLLQISSFNGKMNALNEIN 360
            NEAKNDALSMIIKSLKNLASRISGQDETIKNLEIFRLKMILRLLQISSFNGKMNALNEIN
Sbjct: 301  NEAKNDALSMIIKSLKNLASRISGQDETIKNLEIFRLKMILRLLQISSFNGKMNALNEIN 360

Query: 361  KVISSVSYYTHRHSNPEEEEWLTAERMAEWIQQNNILSIVLQDSLHQPQYVEKLEKILRF 420
            KVISSVSYYTHRHSNPEEEEWLTAERMAEWIQQNNILSIVLQDSLHQPQYVEKLEKILRF
Sbjct: 361  KVISSVSYYTHRHSNPEEEEWLTAERMAEWIQQNNILSIVLQDSLHQPQYVEKLEKILRF 420

Query: 421  VIKEKALTLQDLDNIWAAQAGKHEAIVKNVHDLLAKLAWDFSPGQLDHLFDCFKASWTNA 480
            VIKEKALTLQDLDNIWAAQAGKHEAIVKNVHDLLAKLAWDFSPGQLDHLFDCFKASWTNA
Sbjct: 421  VIKEKALTLQDLDNIWAAQAGKHEAIVKNVHDLLAKLAWDFSPGQLDHLFDCFKASWTNA 480

Query: 481  SKKQREKLLELIRRLAEDDKDGVMAHKVLNLLWNLAQSDDVPVDIMDLALSAHIKILDYS 540
            SKKQREKLLELIRRLAEDDKDGVMAHKVLNLLWNLAQSDDVPVDIMDLALSAHIKILDYS
Sbjct: 481  SKKQREKLLELIRRLAEDDKDGVMAHKVLNLLWNLAQSDDVPVDIMDLALSAHIKILDYS 540

Query: 541  CSQDRDAQKIQWIDHFIEELRTNDKWVIPALKQIREICSLFGEASQNLSQTQRSPHIFYR 600
            CSQDRDAQKIQWIDHFIEELRTNDKWVIPALKQIREICSLFGEASQNLSQTQRSPHIFYR
Sbjct: 541  CSQDRDAQKIQWIDHFIEELRTNDKWVIPALKQIREICSLFGEASQNLSQTQRSPHIFYR 600

Query: 601  HDLINQLQQNHALVTLVAENLATYMNSIRLYAGDHEDYDPQTVRLGSRYSHVQEVQERLN 660
            HDLINQLQQNHALVTLVAENLATYMNSIRLYAGDHEDYDPQTVRLGSRYSHVQEVQERLN
Sbjct: 601  HDLINQLQQNHALVTLVAENLATYMNSIRLYAGDHEDYDPQTVRLGSRYSHVQEVQERLN 660

Query: 661  FLRFLLKDGQLWLCAPQAKQIWKCLAENAVYLCDREACFKWYSKLMGDEPDLDPDINKDF 720
            FLRFLLKDGQLWLCAPQAKQIWKCLAENAVYLCDREACFKWYSKLMGDEPDLDPDINKDF
Sbjct: 661  FLRFLLKDGQLWLCAPQAKQIWKCLAENAVYLCDREACFKWYSKLMGDEPDLDPDINKDF 720

Query: 721  FESNVLQLDPSLLTENGMKCFERFFKAVNCRERKLIAKRRSYMMDDLELIGLDYLWRVVI 780
            FESNVLQLDPSLLTENGMKCFERFFKAVNCRERKLIAKRRSYMMDDLELIGLDYLWRVVI
Sbjct: 721  FESNVLQLDPSLLTENGMKCFERFFKAVNCRERKLIAKRRSYMMDDLELIGLDYLWRVVI 780

Query: 781  QSSDEIANRAIDLLKEIYTNLGPRLKANQVVIHEDFIQSCFDRLKASYDTLCVFDGDKNS 840
            QSSDEIANRAIDLLKEIYTNLGPRLKANQVVIHEDFIQSCFDRLKASYDTLCVFDGDKNS
Sbjct: 781  QSSDEIANRAIDLLKEIYTNLGPRLKANQVVIHEDFIQSCFDRLKASYDTLCVFDGDKNS 840

Query: 841  INCARQEAIRMVRVLTVIKEYINECDSDYHKERMILPMSRAFRGKHLSLIVRFPNQGRQV 900
            INCARQEAIRMVRVLTVIKEYINECDSDYHKERMILPMSRAFRGKHLSLIVRFPNQGRQV
Sbjct: 841  INCARQEAIRMVRVLTVIKEYINECDSDYHKERMILPMSRAFRGKHLSLIVRFPNQGRQV 900

Query: 901  DELDIWSHTNDTIGSVRRCIVNRIKANVAHKKIELFVGGELIDSEDDRKLIGQLNLKDKS 960
            DELDIWSHTNDTIGSVRRCIVNRIKANVAHKKIELFVGGELIDSEDDRKLIGQLNLKDKS
Sbjct: 901  DELDIWSHTNDTIGSVRRCIVNRIKANVAHKKIELFVGGELIDSEDDRKLIGQLNLKDKS 960

Query: 961  LITAKLTQINFNMPSSPDSSSDSSTASPGNHRNHYNDGPNLEVESCLPGVIMSVHPRYIS 1020
            LITAKLTQINFNMPSSPDSSSDSSTASPGNHRNHYNDGPNLEVESCLPGVIMSVHPRYIS
Sbjct: 961  LITAKLTQINFNMPSSPDSSSDSSTASPGNHRNHYNDGPNLEVESCLPGVIMSVHPRYIS 1020

Query: 1021 FLWQVADLGSNLNMPPLRDGARVLMKLMPPDRTAVEKLRAVCLDHAKLGEGKLSPPLDSL 1080
            FLWQVADLGSNLNMPPLRDGARVLMKLMPPDRTAVEKLRAVCLDHAKLGEGKLSPPLDSL
Sbjct: 1021 FLWQVADLGSNLNMPPLRDGARVLMKLMPPDRTAVEKLRAVCLDHAKLGEGKLSPPLDSL 1080

Query: 1081 FFGPSASQVLYLTEVVYALLMPAGVPLTDGSSDFQVHFLKSGGLPLVLSMLIRNNFLPNT 1140
            FFGPSASQVLYLTEVVYALLMPAGVPLTDGSSDFQVHFLKSGGLPLVLSMLIRNNFLPNT
Sbjct: 1081 FFGPSASQVLYLTEVVYALLMPAGVPLTDGSSDFQVHFLKSGGLPLVLSMLIRNNFLPNT 1140

Query: 1141 DMETRRGAYLNALKIAKLLLTAIGYGHVRAVAEACQPVVDGTDPITQINQVTHDQAVVLQ 1200
            DMETRRGAYLNALKIAKLLLTAIGYGHVRAVAEACQPVVDGTDPITQINQVTHDQAVVLQ
Sbjct: 1141 DMETRRGAYLNALKIAKLLLTAIGYGHVRAVAEACQPVVDGTDPITQINQVTHDQAVVLQ 1200

Query: 1201 SALQSIPNPSSECVLRNESILLAQEISNEASRYMPDICVIRAIQKIIWASACGALGLVFS 1260
            SALQSIPNPSSECVLRNESILLAQEISNEASRYMPDICVIRAIQKIIWASACGALGLVFS
Sbjct: 1201 SALQSIPNPSSECVLRNESILLAQEISNEASRYMPDICVIRAIQKIIWASACGALGLVFS 1260

Query: 1261 PNEEITKIYQMTTNGSNKLEVEDEQVCCEALEVMTLCFALLPTALDALSKEKAWQTFIID 1320
            PNEEITKIYQMTTNGSNKLEVEDEQVCCEALEVMTLCFALLPTALDALSKEKAWQTFIID
Sbjct: 1261 PNEEITKIYQMTTNGSNKLEVEDEQVCCEALEVMTLCFALLPTALDALSKEKAWQTFIID 1320

Query: 1321 LLLHCPSKTVRQLAQEQFFLMCTRCCMGHRPLLFFITLLFTILGSTAREKGKYSGDYFTL 1380
            LLLHCPSKTVRQLAQEQFFLMCTRCCMGHRPLLFFITLLFTILGSTAREKGKYSGDYFTL
Sbjct: 1321 LLLHCPSKTVRQLAQEQFFLMCTRCCMGHRPLLFFITLLFTILGSTAREKGKYSGDYFTL 1380

Query: 1381 LRHLLNYAYNGNINIPNAEVLLVSEIDWLKRIRDNVKNTGETGVEEPILEGHLGVTKELL 1440
            LRHLLNYAYNGNINIPNAEVLLVSEIDWLKRIRDNVKNTGETGVEEPILEGHLGVTKELL
Sbjct: 1381 LRHLLNYAYNGNINIPNAEVLLVSEIDWLKRIRDNVKNTGETGVEEPILEGHLGVTKELL 1440

Query: 1441 AFQTSEKKYHFGCEKGGANLIKELIDDFIFPASKVYLQYLRSGELPAEQAIPVCSSPVTI 1500
            AFQTSEKKYHFGCEKGGANLIKELIDDFIFPASKVYLQYLRSGELPAEQAIPVCSSPVTI
Sbjct: 1441 AFQTSEKKYHFGCEKGGANLIKELIDDFIFPASKVYLQYLRSGELPAEQAIPVCSSPVTI 1500

Query: 1501 NAGFELLVALAIGCVRNLKQIVDCLTEMYYMGTAITTCEALTEWEYLPPVGPRPPKGFVG 1560
            NAGFELLVALAIGCVRNLKQIVDCLTEMYYMGTAITTCEALTEWEYLPPVGPRPPKGFVG
Sbjct: 1501 NAGFELLVALAIGCVRNLKQIVDCLTEMYYMGTAITTCEALTEWEYLPPVGPRPPKGFVG 1560

Query: 1561 LKNAGATCYMNSVIQQLYMIPSIRNSILAIEGTGSDLHDDMFGDEKQDSESNVDPRDDVF 1620
            LKNAGATCYMNSVIQQLYMIPSIRNSILAIEGTGSDLHDDMFGDEKQDSESNVDPRDDVF
Sbjct: 1561 LKNAGATCYMNSVIQQLYMIPSIRNSILAIEGTGSDLHDDMFGDEKQDSESNVDPRDDVF 1620

Query: 1621 GYPHQFEDKPALSKTEDRKEYNIGVLRHLQVIFGHLAASQLQYYVPRGFWKQFRLWGEPV 1680
            GYPHQFEDKPALSKTEDRKEYNIGVLRHLQVIFGHLAASQLQYYVPRGFWKQFRLWGEPV
Sbjct: 1621 GYPHQFEDKPALSKTEDRKEYNIGVLRHLQVIFGHLAASQLQYYVPRGFWKQFRLWGEPV 1680

Query: 1681 NLREQHDALEFFNSLVDSLDEALKALGHPAILSKVLGGSFADQKICQGCPHRYECEESFT 1740
            NLREQHDALEFFNSLVDSLDEALKALGHPAILSKVLGGSFADQKICQGCPHRYECEESFT
Sbjct: 1681 NLREQHDALEFFNSLVDSLDEALKALGHPAILSKVLGGSFADQKICQGCPHRYECEESFT 1740

Query: 1741 TLNVDIRNHQNLLDSLEQYIKGDLLEGANAYHCEKCDKKVDTVKRLLIKKLPRVLAIQLK 1800
            TLNVDIRNHQNLLDSLEQYIKGDLLEGANAYHCEKCDKKVDTVKRLLIKKLPRVLAIQLK
Sbjct: 1741 TLNVDIRNHQNLLDSLEQYIKGDLLEGANAYHCEKCDKKVDTVKRLLIKKLPRVLAIQLK 1800

Query: 1801 RFDYDWERECAIKFNDYFEFPRELDMGPYTVAGVANLERDNVNSENELIEQKEQSDNETA 1860
            RFDYDWERECAIKFNDYFEFPRELDMGPYTVAGVANLERDNVNSENELIEQKEQSDNETA
Sbjct: 1801 RFDYDWERECAIKFNDYFEFPRELDMGPYTVAGVANLERDNVNSENELIEQKEQSDNETA 1860

Query: 1861 GGTKYRLVGVLVHSGQASGGHYYSYIIQRNGKDDQTDHWYKFDDGDVTECKMDDDEEMKN 1920
            GGTKYRLVGVLVHSGQASGGHYYSYIIQRNGKDDQTDHWYKFDDGDVTECKMDDDEEMKN
Sbjct: 1861 GGTKYRLVGVLVHSGQASGGHYYSYIIQRNGKDDQTDHWYKFDDGDVTECKMDDDEEMKN 1920

Query: 1921 QCFGGEYMGEVFDHMMKRMSYRRQKRWWNAYILFYEQMDMIDEDDEMIRYISELTIARPH 1980
            QCFGGEYMGEVFDHMMKRMSYRRQKRWWNAYILFYEQMDMIDEDDEMIRYISELTIARPH
Sbjct: 1921 QCFGGEYMGEVFDHMMKRMSYRRQKRWWNAYILFYEQMDMIDEDDEMIRYISELTIARPH 1980

Query: 1981 QIIMSPAIERSVRKQNVKFMHNRLQYSLEYFQFVKKLLTCNGVYLNPAPGQDYLLPEAEE 2040
            QIIMSPAIERSVRKQNVKFMHNRLQYSLEYFQFVKKLLTCNGVYLNPAPGQDYLLPEAEE
Sbjct: 1981 QIIMSPAIERSVRKQNVKFMHNRLQYSLEYFQFVKKLLTCNGVYLNPAPGQDYLLPEAEE 2040

Query: 2041 ITMISIQLAARFLFTTGFHTKKIVRGPASDWYDALCVLLRHSKNVRFWFTHNVLFNVSNR 2100
            ITMISIQLAARFLFTTGFHTKKIVRGPASDWYDALCVLLRHSKNVRFWFTHNVLFNVSNR
Sbjct: 2041 ITMISIQLAARFLFTTGFHTKKIVRGPASDWYDALCVLLRHSKNVRFWFTHNVLFNVSNR 2100

Query: 2101 FSEYLLECPSAEVRGAFAKLIVFIAHFSLQDGSCPSPFASPGPSSQACDNLSLSDHLLRA 2160
            FSEYLLECPSAEVRGAFAKLIVFIAHFSLQDGSCPSPFASPGPSSQACDNLSLSDHLLRA
Sbjct: 2101 FSEYLLECPSAEVRGAFAKLIVFIAHFSLQDGSCPSPFASPGPSSQACDNLSLSDHLLRA 2160

Query: 2161 TLNLLRREVSEHGHHLQQYFNLFVMYANLGVAEKTQLLKLNVPATFMLVSLDEGPGPPIK 2220
            TLNLLRREVSEHGHHLQQYFNLFVMYANLGVAEKTQLLKLNVPATFMLVSLDEGPGPPIK
Sbjct: 2161 TLNLLRREVSEHGHHLQQYFNLFVMYANLGVAEKTQLLKLNVPATFMLVSLDEGPGPPIK 2220

Query: 2221 YQYAELGKLYSVVSQLIRCCNVSSTMQSSINGNPPLPNPFGDLNLSQPIMPIQQNVLDIL 2280
            YQYAELGKLYSVVSQLIRCCNVSSTMQSSINGNPPLPNPFGDLNLSQPIMPIQQNVLDIL
Sbjct: 2221 YQYAELGKLYSVVSQLIRCCNVSSTMQSSINGNPPLPNPFGDLNLSQPIMPIQQNVLDIL 2280

Query: 2281 FVRTSYVKKIIEDCSNSEDTIKLLRFCSWENPQFSSTVLSELLWQVAYSYTYELRPYLDL 2340
            FVRTSYVKKIIEDCSNSEDTIKLLRFCSWENPQFSSTVLSELLWQVAYSYTYELRPYLDL
Sbjct: 2281 FVRTSYVKKIIEDCSNSEDTIKLLRFCSWENPQFSSTVLSELLWQVAYSYTYELRPYLDL 2340

Query: 2341 LFQILLIEDSWQTHRIHNALKGIPDDRDGLFDTIQRSKNHYQKRAYQCIKCMVALFSSCP 2400
            LFQILLIEDSWQTHRIHNALKGIPDDRDGLFDTIQRSKNHYQKRAYQCIKCMVALFSSCP
Sbjct: 2341 LFQILLIEDSWQTHRIHNALKGIPDDRDGLFDTIQRSKNHYQKRAYQCIKCMVALFSSCP 2400

Query: 2401 VAYQILQGNGDLKRKWTWAVEWLGDELERRPYTGNPQYSYNNWSPPVQSNETANGYFLER 2460
            VAYQILQGNGDLKRKWTWAVEWLGDELERRPYTGNPQYSYNNWSPPVQSNETANGYFLER
Sbjct: 2401 VAYQILQGNGDLKRKWTWAVEWLGDELERRPYTGNPQYSYNNWSPPVQSNETANGYFLER 2460

Query: 2461 SHSARMTLAKACELCPEEEPDDQDAPDEHEPSPSEDAPLYPHSPASQYQQNNHVHGQPYT 2520
            SHSARMTLAKACELCPEEEPDDQDAPDEHEPSPSEDAPLYPHSPASQYQQNNHVHGQPYT
Sbjct: 2461 SHSARMTLAKACELCPEEEPDDQDAPDEHEPSPSEDAPLYPHSPASQYQQNNHVHGQPYT 2520

Query: 2521 GPAAHHLNNPQKTGQRTQENYEGNEEVSSPQMKDQ 2555
            GPAAHHLNNPQKTGQRTQENYEGNEEVSSPQMKDQ
Sbjct: 2521 GPAAHHLNNPQKTGQRTQENYEGNEEVSSPQMKDQ 2555


>gi|145309311 ubiquitin specific protease 9, X-linked isoform 4 [Homo
            sapiens]
          Length = 2554

 Score = 4808 bits (12470), Expect = 0.0
 Identities = 2341/2556 (91%), Positives = 2441/2556 (95%), Gaps = 3/2556 (0%)

Query: 1    MTAITHGSPVGGNDSQGQVLDGQSQHLFQQNQTSSPDSSNENSVATPPPEEQGQGDAPPQ 60
            MTA T GSPVGGND+QGQ  DGQSQ   QQNQTSSPDSSNENS ATPP +EQGQGDAPPQ
Sbjct: 1    MTATTRGSPVGGNDNQGQAPDGQSQPPLQQNQTSSPDSSNENSPATPP-DEQGQGDAPPQ 59

Query: 61   HEDEEPAFPHTELANLDDMINRPRWVVPVLPKGELEVLLEAAIDLSVKGLDVKSEACQRF 120
             EDEEPAFPHT+LA LDDMINRPRWVVPVLPKGELEVLLEAAIDLS KGLDVKSEACQRF
Sbjct: 60   LEDEEPAFPHTDLAKLDDMINRPRWVVPVLPKGELEVLLEAAIDLSKKGLDVKSEACQRF 119

Query: 121  FRDGLTISFTKILMDEAVSGWKFEIHRCIINNTHRLVELCVAKLSQDWFPLLELLAMALN 180
            FRDGLTISFTKIL DEAVSGWKFEIHRCIINNTHRLVELCVAKLSQDWFPLLELLAMALN
Sbjct: 120  FRDGLTISFTKILTDEAVSGWKFEIHRCIINNTHRLVELCVAKLSQDWFPLLELLAMALN 179

Query: 181  PHCKFHIYNGTRPCELISSNAQLPEDELFARSSDPRSPKGWLVDLINKFGTLNGFQILHD 240
            PHCKFHIYNGTRPCE +SS+ QLPEDELFARS DPRSPKGWLVDL+NKFGTLNGFQILHD
Sbjct: 180  PHCKFHIYNGTRPCESVSSSVQLPEDELFARSPDPRSPKGWLVDLLNKFGTLNGFQILHD 239

Query: 241  RFFNGSALNIQIIAALIKPFGQCYEFLSQHTLKKYFIPVIEIVPHLLENLTDEELKKEAK 300
            RF NGSALN+QIIAALIKPFGQCYEFL+ HT+KKYF+P+IE+VP  LENLTDEELKKEAK
Sbjct: 240  RFINGSALNVQIIAALIKPFGQCYEFLTLHTVKKYFLPIIEMVPQFLENLTDEELKKEAK 299

Query: 301  NEAKNDALSMIIKSLKNLASRISGQDETIKNLEIFRLKMILRLLQISSFNGKMNALNEIN 360
            NEAKNDALSMIIKSLKNLASR+ GQ+ET+KNLEIFRLKMILRLLQISSFNGKMNALNE+N
Sbjct: 300  NEAKNDALSMIIKSLKNLASRVPGQEETVKNLEIFRLKMILRLLQISSFNGKMNALNEVN 359

Query: 361  KVISSVSYYTHRHSNPEEEEWLTAERMAEWIQQNNILSIVLQDSLHQPQYVEKLEKILRF 420
            KVISSVSYYTHRH NPEEEEWLTAERMAEWIQQNNILSIVL+DSLHQPQYVEKLEKILRF
Sbjct: 360  KVISSVSYYTHRHGNPEEEEWLTAERMAEWIQQNNILSIVLRDSLHQPQYVEKLEKILRF 419

Query: 421  VIKEKALTLQDLDNIWAAQAGKHEAIVKNVHDLLAKLAWDFSPGQLDHLFDCFKASWTNA 480
            VIKEKALTLQDLDNIWAAQAGKHEAIVKNVHDLLAKLAWDFSP QLDHLFDCFKASWTNA
Sbjct: 420  VIKEKALTLQDLDNIWAAQAGKHEAIVKNVHDLLAKLAWDFSPEQLDHLFDCFKASWTNA 479

Query: 481  SKKQREKLLELIRRLAEDDKDGVMAHKVLNLLWNLAQSDDVPVDIMDLALSAHIKILDYS 540
            SKKQREKLLELIRRLAEDDKDGVMAHKVLNLLWNLA SDDVPVDIMDLALSAHIKILDYS
Sbjct: 480  SKKQREKLLELIRRLAEDDKDGVMAHKVLNLLWNLAHSDDVPVDIMDLALSAHIKILDYS 539

Query: 541  CSQDRDAQKIQWIDHFIEELRTNDKWVIPALKQIREICSLFGEASQNLSQTQRSPHIFYR 600
            CSQDRD QKIQWID FIEELRTNDKWVIPALKQIREICSLFGEA QNLSQTQRSPH+FYR
Sbjct: 540  CSQDRDTQKIQWIDRFIEELRTNDKWVIPALKQIREICSLFGEAPQNLSQTQRSPHVFYR 599

Query: 601  HDLINQLQQNHALVTLVAENLATYMNSIRLYAGDHEDYDPQTVRLGSRYSHVQEVQERLN 660
            HDLINQLQ NHALVTLVAENLATYM S+RLYA DHEDYDPQTVRLGSRYSHVQEVQERLN
Sbjct: 600  HDLINQLQHNHALVTLVAENLATYMESMRLYARDHEDYDPQTVRLGSRYSHVQEVQERLN 659

Query: 661  FLRFLLKDGQLWLCAPQAKQIWKCLAENAVYLCDREACFKWYSKLMGDEPDLDPDINKDF 720
            FLRFLLKDGQLWLCAPQAKQIWKCLAENAVYLCDREACFKWYSKLMGDEPDLDPDINKDF
Sbjct: 660  FLRFLLKDGQLWLCAPQAKQIWKCLAENAVYLCDREACFKWYSKLMGDEPDLDPDINKDF 719

Query: 721  FESNVLQLDPSLLTENGMKCFERFFKAVNCRERKLIAKRRSYMMDDLELIGLDYLWRVVI 780
            FESNVLQLDPSLLTENGMKCFERFFKAVNCRE KL+AKRR+YMMDDLELIGLDYLWRVVI
Sbjct: 720  FESNVLQLDPSLLTENGMKCFERFFKAVNCREGKLVAKRRAYMMDDLELIGLDYLWRVVI 779

Query: 781  QSSDEIANRAIDLLKEIYTNLGPRLKANQVVIHEDFIQSCFDRLKASYDTLCVFDGDKNS 840
            QS+D+IA+RAIDLLKEIYTNLGPRL+ NQVVIHEDFIQSCFDRLKASYDTLCV DGDK+S
Sbjct: 780  QSNDDIASRAIDLLKEIYTNLGPRLQVNQVVIHEDFIQSCFDRLKASYDTLCVLDGDKDS 839

Query: 841  INCARQEAIRMVRVLTVIKEYINECDSDYHKERMILPMSRAFRGKHLSLIVRFPNQGRQV 900
            +NCARQEA+RMVRVLTV++EYINECDSDYH+ER ILPMSRAFRGKHLS +VRFPNQGRQV
Sbjct: 840  VNCARQEAVRMVRVLTVLREYINECDSDYHEERTILPMSRAFRGKHLSFVVRFPNQGRQV 899

Query: 901  DELDIWSHTNDTIGSVRRCIVNRIKANVAHKKIELFVGGELIDSEDDRKLIGQLNLKDKS 960
            D+L++WSHTNDTIGSVRRCI+NRIKANVAH KIELFVGGELID  DDRKLIGQLNLKDKS
Sbjct: 900  DDLEVWSHTNDTIGSVRRCILNRIKANVAHTKIELFVGGELIDPADDRKLIGQLNLKDKS 959

Query: 961  LITAKLTQINFNMPSSPDSSSDSSTASPGNHRNHYNDGPNLEVESCLPGVIMSVHPRYIS 1020
            LITAKLTQI+ NMPSSPDSSSDSST SPGNH NHY+DGPN EVESCLPGVIMS+HPRYIS
Sbjct: 960  LITAKLTQISSNMPSSPDSSSDSSTGSPGNHGNHYSDGPNPEVESCLPGVIMSLHPRYIS 1019

Query: 1021 FLWQVADLGSNLNMPPLRDGARVLMKLMPPDRTAVEKLRAVCLDHAKLGEGKLSPPLDSL 1080
            FLWQVADLGS+LNMPPLRDGARVLMKLMPPD T +EKLRA+CLDHAKLGE  LSP LDSL
Sbjct: 1020 FLWQVADLGSSLNMPPLRDGARVLMKLMPPDSTTIEKLRAICLDHAKLGESSLSPSLDSL 1079

Query: 1081 FFGPSASQVLYLTEVVYALLMPAGVPLTDGSSDFQVHFLKSGGLPLVLSMLIRNNFLPNT 1140
            FFGPSASQVLYLTEVVYALLMPAG PL D SSDFQ HFLKSGGLPLVLSML RNNFLPN 
Sbjct: 1080 FFGPSASQVLYLTEVVYALLMPAGAPLADDSSDFQFHFLKSGGLPLVLSMLTRNNFLPNA 1139

Query: 1141 DMETRRGAYLNALKIAKLLLTAIGYGHVRAVAEACQPVVDGTDPITQINQVTHDQAVVLQ 1200
            DMETRRGAYLNALKIAKLLLTAIGYGHVRAVAEACQP V+G +P+TQINQVTHDQAVVLQ
Sbjct: 1140 DMETRRGAYLNALKIAKLLLTAIGYGHVRAVAEACQPGVEGVNPMTQINQVTHDQAVVLQ 1199

Query: 1201 SALQSIPNPSSECVLRNESILLAQEISNEASRYMPDICVIRAIQKIIWASACGALGLVFS 1260
            SALQSIPNPSSEC+LRN S+ LAQ+IS+EASRYMPDICVIRAIQKIIWAS CG+L LVFS
Sbjct: 1200 SALQSIPNPSSECMLRNVSVRLAQQISDEASRYMPDICVIRAIQKIIWASGCGSLQLVFS 1259

Query: 1261 PNEEITKIYQMTTNGSNKLEVEDEQVCCEALEVMTLCFALLPTALDALSKEKAWQTFIID 1320
            PNEEITKIY+  TN  N+ ++EDEQVCCEALEVMTLCFAL+PTALDALSKEKAWQTFIID
Sbjct: 1260 PNEEITKIYE-KTNAGNEPDLEDEQVCCEALEVMTLCFALIPTALDALSKEKAWQTFIID 1318

Query: 1321 LLLHCPSKTVRQLAQEQFFLMCTRCCMGHRPLLFFITLLFTILGSTAREKGKYSGDYFTL 1380
            LLLHC SKTVRQ+AQEQFFLMCTRCCMGHRPLLFFITLLFT+LGSTARE+ K+SGDYFTL
Sbjct: 1319 LLLHCHSKTVRQVAQEQFFLMCTRCCMGHRPLLFFITLLFTVLGSTARERAKHSGDYFTL 1378

Query: 1381 LRHLLNYAYNGNINIPNAEVLLVSEIDWLKRIRDNVKNTGETGVEEPILEGHLGVTKELL 1440
            LRHLLNYAYN NIN+PNAEVLL +EIDWLKRIRD+VK TGETG+EE ILEGHLGVTKELL
Sbjct: 1379 LRHLLNYAYNSNINVPNAEVLLNNEIDWLKRIRDDVKRTGETGIEETILEGHLGVTKELL 1438

Query: 1441 AFQTSEKKYHFGCEKGGANLIKELIDDFIFPASKVYLQYLRSGELPAEQAIPVCSSPVTI 1500
            AFQTSEKK+H GCEKGGANLIKELIDDFIFPAS VYLQY+R+GELPAEQAIPVC SP TI
Sbjct: 1439 AFQTSEKKFHIGCEKGGANLIKELIDDFIFPASNVYLQYMRNGELPAEQAIPVCGSPPTI 1498

Query: 1501 NAGFELLVALAIGCVRNLKQIVDCLTEMYYMGTAITTCEALTEWEYLPPVGPRPPKGFVG 1560
            NAGFELLVALA+GCVRNLKQIVD LTEMYY+GTAITTCEALTEWEYLPPVGPRPPKGFVG
Sbjct: 1499 NAGFELLVALAVGCVRNLKQIVDSLTEMYYIGTAITTCEALTEWEYLPPVGPRPPKGFVG 1558

Query: 1561 LKNAGATCYMNSVIQQLYMIPSIRNSILAIEGTGSDLHDDMFGDEKQDSESNVDPRDDVF 1620
            LKNAGATCYMNSVIQQLYMIPSIRN ILAIEGTGSD+ DDM GDEKQD+ESNVDPRDDVF
Sbjct: 1559 LKNAGATCYMNSVIQQLYMIPSIRNGILAIEGTGSDVDDDMSGDEKQDNESNVDPRDDVF 1618

Query: 1621 GYPHQFEDKPALSKTEDRKEYNIGVLRHLQVIFGHLAASQLQYYVPRGFWKQFRLWGEPV 1680
            GYP QFEDKPALSKTEDRKEYNIGVLRHLQVIFGHLAAS+LQYYVPRGFWKQFRLWGEPV
Sbjct: 1619 GYPQQFEDKPALSKTEDRKEYNIGVLRHLQVIFGHLAASRLQYYVPRGFWKQFRLWGEPV 1678

Query: 1681 NLREQHDALEFFNSLVDSLDEALKALGHPAILSKVLGGSFADQKICQGCPHRYECEESFT 1740
            NLREQHDALEFFNSLVDSLDEALKALGHPA+LSKVLGGSFADQKICQGCPHRYECEESFT
Sbjct: 1679 NLREQHDALEFFNSLVDSLDEALKALGHPAMLSKVLGGSFADQKICQGCPHRYECEESFT 1738

Query: 1741 TLNVDIRNHQNLLDSLEQYIKGDLLEGANAYHCEKCDKKVDTVKRLLIKKLPRVLAIQLK 1800
            TLNVDIRNHQNLLDSLEQY+KGDLLEGANAYHCEKC+KKVDTVKRLLIKKLP VLAIQLK
Sbjct: 1739 TLNVDIRNHQNLLDSLEQYVKGDLLEGANAYHCEKCNKKVDTVKRLLIKKLPPVLAIQLK 1798

Query: 1801 RFDYDWERECAIKFNDYFEFPRELDMGPYTVAGVANLERDNVNSENELIEQKEQSDNETA 1860
            RFDYDWERECAIKFNDYFEFPRELDM PYTVAGVA LE DNVN E++LI+Q EQS++ETA
Sbjct: 1799 RFDYDWERECAIKFNDYFEFPRELDMEPYTVAGVAKLEGDNVNPESQLIQQSEQSESETA 1858

Query: 1861 GGTKYRLVGVLVHSGQASGGHYYSYIIQRNGKDDQTDHWYKFDDGDVTECKMDDDEEMKN 1920
            G TKYRLVGVLVHSGQASGGHYYSYIIQRNG D + + WYKFDDGDVTECKMDDDEEMKN
Sbjct: 1859 GSTKYRLVGVLVHSGQASGGHYYSYIIQRNGGDGERNRWYKFDDGDVTECKMDDDEEMKN 1918

Query: 1921 QCFGGEYMGEVFDHMMKRMSYRRQKRWWNAYILFYEQMDMIDEDDEMIRYISELTI-ARP 1979
            QCFGGEYMGEVFDHMMKRMSYRRQKRWWNAYILFYE+MD ID+DDE+IRYISEL I  RP
Sbjct: 1919 QCFGGEYMGEVFDHMMKRMSYRRQKRWWNAYILFYERMDTIDQDDELIRYISELAITTRP 1978

Query: 1980 HQIIMSPAIERSVRKQNVKFMHNRLQYSLEYFQFVKKLLTCNGVYLNPAPGQDYLLPEAE 2039
            HQIIM  AIERSVRKQNV+FMHNR+QYS+EYFQF+KKLLTCNGVYLNP PGQD+LLPEAE
Sbjct: 1979 HQIIMPSAIERSVRKQNVQFMHNRMQYSMEYFQFMKKLLTCNGVYLNPPPGQDHLLPEAE 2038

Query: 2040 EITMISIQLAARFLFTTGFHTKKIVRGPASDWYDALCVLLRHSKNVRFWFTHNVLFNVSN 2099
            EITMISIQLAARFLFTTGFHTKK+VRG ASDWYDALC+LLRHSKNVRFWF HNVLFNVSN
Sbjct: 2039 EITMISIQLAARFLFTTGFHTKKVVRGSASDWYDALCILLRHSKNVRFWFAHNVLFNVSN 2098

Query: 2100 RFSEYLLECPSAEVRGAFAKLIVFIAHFSLQDGSCPSPFASPGPSSQACDNLSLSDHLLR 2159
            RFSEYLLECPSAEVRGAFAKLIVFIAHFSLQDG CPSPFASPGPSSQA DNLSLSDHLLR
Sbjct: 2099 RFSEYLLECPSAEVRGAFAKLIVFIAHFSLQDGPCPSPFASPGPSSQAYDNLSLSDHLLR 2158

Query: 2160 ATLNLLRREVSEHGHHLQQYFNLFVMYANLGVAEKTQLLKLNVPATFMLVSLDEGPGPPI 2219
            A LNLLRREVSEHG HLQQYFNLFVMYANLGVAEKTQLLKL+VPATFMLVSLDEGPGPPI
Sbjct: 2159 AVLNLLRREVSEHGRHLQQYFNLFVMYANLGVAEKTQLLKLSVPATFMLVSLDEGPGPPI 2218

Query: 2220 KYQYAELGKLYSVVSQLIRCCNVSSTMQSSINGNPPLPNPFGDLNLSQPIMPIQQNVLDI 2279
            KYQYAELGKLYSVVSQLIRCCNVSS MQSSINGNPPLPNPFGD NLSQPIMPIQQNV DI
Sbjct: 2219 KYQYAELGKLYSVVSQLIRCCNVSSRMQSSINGNPPLPNPFGDPNLSQPIMPIQQNVADI 2278

Query: 2280 LFVRTSYVKKIIEDCSNSEDTIKLLRFCSWENPQFSSTVLSELLWQVAYSYTYELRPYLD 2339
            LFVRTSYVKKIIEDCSNSE+T+KLLRFC WENPQFSSTVLSELLWQVAYSYTYELRPYLD
Sbjct: 2279 LFVRTSYVKKIIEDCSNSEETVKLLRFCCWENPQFSSTVLSELLWQVAYSYTYELRPYLD 2338

Query: 2340 LLFQILLIEDSWQTHRIHNALKGIPDDRDGLFDTIQRSKNHYQKRAYQCIKCMVALFSSC 2399
            LL QILLIEDSWQTHRIHNALKGIPDDRDGLFDTIQRSKNHYQKRAYQCIKCMVALFS+C
Sbjct: 2339 LLLQILLIEDSWQTHRIHNALKGIPDDRDGLFDTIQRSKNHYQKRAYQCIKCMVALFSNC 2398

Query: 2400 PVAYQILQGNGDLKRKWTWAVEWLGDELERRPYTGNPQYSYNNWSPPVQSNETANGYFLE 2459
            PVAYQILQGNGDLKRKWTWAVEWLGDELERRPYTGNPQY+YNNWSPPVQSNET+NGYFLE
Sbjct: 2399 PVAYQILQGNGDLKRKWTWAVEWLGDELERRPYTGNPQYTYNNWSPPVQSNETSNGYFLE 2458

Query: 2460 RSHSARMTLAKACELCPEEEPDDQDAPDEHEPSPSEDAPLYPHSPASQYQQNNHVHGQPY 2519
            RSHSARMTLAKACELCPEEEPDDQDAPDEHE  P EDAPLYPHSP SQYQQNNHVHGQPY
Sbjct: 2459 RSHSARMTLAKACELCPEEEPDDQDAPDEHESPPPEDAPLYPHSPGSQYQQNNHVHGQPY 2518

Query: 2520 TGPAAHHLNNPQKTGQRTQENYEGNEEVSSPQMKDQ 2555
            TGPAAHH+NNPQ+TGQR QENYEG+EEVS PQ KDQ
Sbjct: 2519 TGPAAHHMNNPQRTGQRAQENYEGSEEVSPPQTKDQ 2554


>gi|145309309 ubiquitin specific protease 9, X-linked isoform 3 [Homo
            sapiens]
          Length = 2570

 Score = 4797 bits (12443), Expect = 0.0
 Identities = 2341/2572 (91%), Positives = 2441/2572 (94%), Gaps = 19/2572 (0%)

Query: 1    MTAITHGSPVGGNDSQGQVLDGQSQHLFQQNQTSSPDSSNENSVATPPPEEQGQGDAPPQ 60
            MTA T GSPVGGND+QGQ  DGQSQ   QQNQTSSPDSSNENS ATPP +EQGQGDAPPQ
Sbjct: 1    MTATTRGSPVGGNDNQGQAPDGQSQPPLQQNQTSSPDSSNENSPATPP-DEQGQGDAPPQ 59

Query: 61   HEDEEPAFPHTELANLDDMINRPRWVVPVLPKGELEVLLEAAIDLSVKGLDVKSEACQRF 120
             EDEEPAFPHT+LA LDDMINRPRWVVPVLPKGELEVLLEAAIDLS KGLDVKSEACQRF
Sbjct: 60   LEDEEPAFPHTDLAKLDDMINRPRWVVPVLPKGELEVLLEAAIDLSKKGLDVKSEACQRF 119

Query: 121  FRDGLTISFTKILMDEAVSGWKFEIHRCIINNTHRLVELCVAKLSQDWFPLLELLAMALN 180
            FRDGLTISFTKIL DEAVSGWKFEIHRCIINNTHRLVELCVAKLSQDWFPLLELLAMALN
Sbjct: 120  FRDGLTISFTKILTDEAVSGWKFEIHRCIINNTHRLVELCVAKLSQDWFPLLELLAMALN 179

Query: 181  PHCKFHIYNGTRPCELISSNAQLPEDELFARSSDPRSPKGWLVDLINKFGTLNGFQILHD 240
            PHCKFHIYNGTRPCE +SS+ QLPEDELFARS DPRSPKGWLVDL+NKFGTLNGFQILHD
Sbjct: 180  PHCKFHIYNGTRPCESVSSSVQLPEDELFARSPDPRSPKGWLVDLLNKFGTLNGFQILHD 239

Query: 241  RFFNGSALNIQIIAALIKPFGQCYEFLSQHTLKKYFIPVIEIVPHLLENLTDEELKKEAK 300
            RF NGSALN+QIIAALIKPFGQCYEFL+ HT+KKYF+P+IE+VP  LENLTDEELKKEAK
Sbjct: 240  RFINGSALNVQIIAALIKPFGQCYEFLTLHTVKKYFLPIIEMVPQFLENLTDEELKKEAK 299

Query: 301  NEAKNDALSMIIKSLKNLASRISGQDETIKNLEIFRLKMILRLLQISSFNGKMNALNEIN 360
            NEAKNDALSMIIKSLKNLASR+ GQ+ET+KNLEIFRLKMILRLLQISSFNGKMNALNE+N
Sbjct: 300  NEAKNDALSMIIKSLKNLASRVPGQEETVKNLEIFRLKMILRLLQISSFNGKMNALNEVN 359

Query: 361  KVISSVSYYTHRHSNPEEEEWLTAERMAEWIQQNNILSIVLQDSLHQPQYVEKLEKILRF 420
            KVISSVSYYTHRH NPEEEEWLTAERMAEWIQQNNILSIVL+DSLHQPQYVEKLEKILRF
Sbjct: 360  KVISSVSYYTHRHGNPEEEEWLTAERMAEWIQQNNILSIVLRDSLHQPQYVEKLEKILRF 419

Query: 421  VIKEKALTLQDLDNIWAAQAGKHEAIVKNVHDLLAKLAWDFSPGQLDHLFDCFKASWTNA 480
            VIKEKALTLQDLDNIWAAQAGKHEAIVKNVHDLLAKLAWDFSP QLDHLFDCFKASWTNA
Sbjct: 420  VIKEKALTLQDLDNIWAAQAGKHEAIVKNVHDLLAKLAWDFSPEQLDHLFDCFKASWTNA 479

Query: 481  SKKQREKLLELIRRLAEDDKDGVMAHKVLNLLWNLAQSDDVPVDIMDLALSAHIKILDYS 540
            SKKQREKLLELIRRLAEDDKDGVMAHKVLNLLWNLA SDDVPVDIMDLALSAHIKILDYS
Sbjct: 480  SKKQREKLLELIRRLAEDDKDGVMAHKVLNLLWNLAHSDDVPVDIMDLALSAHIKILDYS 539

Query: 541  CSQDRDAQKIQWIDHFIEELRTNDKWVIPALKQIREICSLFGEASQNLSQTQRSPHIFYR 600
            CSQDRD QKIQWID FIEELRTNDKWVIPALKQIREICSLFGEA QNLSQTQRSPH+FYR
Sbjct: 540  CSQDRDTQKIQWIDRFIEELRTNDKWVIPALKQIREICSLFGEAPQNLSQTQRSPHVFYR 599

Query: 601  HDLINQLQQNHALVTLVAENLATYMNSIRLYAGDHEDYDPQTVRLGSRYSHVQEVQERLN 660
            HDLINQLQ NHALVTLVAENLATYM S+RLYA DHEDYDPQTVRLGSRYSHVQEVQERLN
Sbjct: 600  HDLINQLQHNHALVTLVAENLATYMESMRLYARDHEDYDPQTVRLGSRYSHVQEVQERLN 659

Query: 661  FLRFLLKDGQLWLCAPQAKQIWKCLAENAVYLCDREACFKWYSKLMGDEPDLDPDINKDF 720
            FLRFLLKDGQLWLCAPQAKQIWKCLAENAVYLCDREACFKWYSKLMGDEPDLDPDINKDF
Sbjct: 660  FLRFLLKDGQLWLCAPQAKQIWKCLAENAVYLCDREACFKWYSKLMGDEPDLDPDINKDF 719

Query: 721  FESNVLQLDPSLLTENGMKCFERFFKAVNCRERKLIAKRRSYMMDDLELIGLDYLWRVVI 780
            FESNVLQLDPSLLTENGMKCFERFFKAVNCRE KL+AKRR+YMMDDLELIGLDYLWRVVI
Sbjct: 720  FESNVLQLDPSLLTENGMKCFERFFKAVNCREGKLVAKRRAYMMDDLELIGLDYLWRVVI 779

Query: 781  QSSDEIANRAIDLLKEIYTNLGPRLKANQVVIHEDFIQSCFDRLKASYDTLCVFDGDKNS 840
            QS+D+IA+RAIDLLKEIYTNLGPRL+ NQVVIHEDFIQSCFDRLKASYDTLCV DGDK+S
Sbjct: 780  QSNDDIASRAIDLLKEIYTNLGPRLQVNQVVIHEDFIQSCFDRLKASYDTLCVLDGDKDS 839

Query: 841  INCARQEAIRMVRVLTVIKEYINECDSDYHKERMILPMSRAFRGKHLSLIVRFPNQGRQV 900
            +NCARQEA+RMVRVLTV++EYINECDSDYH+ER ILPMSRAFRGKHLS +VRFPNQGRQV
Sbjct: 840  VNCARQEAVRMVRVLTVLREYINECDSDYHEERTILPMSRAFRGKHLSFVVRFPNQGRQV 899

Query: 901  DELDIWSHTNDTIGSVRRCIVNRIKANVAHKKIELFVGGELIDSEDDRKLIGQLNLKDKS 960
            D+L++WSHTNDTIGSVRRCI+NRIKANVAH KIELFVGGELID  DDRKLIGQLNLKDKS
Sbjct: 900  DDLEVWSHTNDTIGSVRRCILNRIKANVAHTKIELFVGGELIDPADDRKLIGQLNLKDKS 959

Query: 961  LITAKLTQINFNMPSSPDSSSDSSTASPGNHRNHYNDGPNLEVESCLPGVIMSVHPRYIS 1020
            LITAKLTQI+ NMPSSPDSSSDSST SPGNH NHY+DGPN EVESCLPGVIMS+HPRYIS
Sbjct: 960  LITAKLTQISSNMPSSPDSSSDSSTGSPGNHGNHYSDGPNPEVESCLPGVIMSLHPRYIS 1019

Query: 1021 FLWQVADLGSNLNMPPLRDGARVLMKLMPPDRTAVEKLRAVCLDHAKLGEGKLSPPLDSL 1080
            FLWQVADLGS+LNMPPLRDGARVLMKLMPPD T +EKLRA+CLDHAKLGE  LSP LDSL
Sbjct: 1020 FLWQVADLGSSLNMPPLRDGARVLMKLMPPDSTTIEKLRAICLDHAKLGESSLSPSLDSL 1079

Query: 1081 FFGPSASQVLYLTEVVYALLMPAGVPLTDGSSDFQVHFLKSGGLPLVLSMLIRNNFLPNT 1140
            FFGPSASQVLYLTEVVYALLMPAG PL D SSDFQ HFLKSGGLPLVLSML RNNFLPN 
Sbjct: 1080 FFGPSASQVLYLTEVVYALLMPAGAPLADDSSDFQFHFLKSGGLPLVLSMLTRNNFLPNA 1139

Query: 1141 DMETRRGAYLNALKIAKLLLTAIGYGHVRAVAEACQPVVDGTDPITQINQVTHDQAVVLQ 1200
            DMETRRGAYLNALKIAKLLLTAIGYGHVRAVAEACQP V+G +P+TQINQVTHDQAVVLQ
Sbjct: 1140 DMETRRGAYLNALKIAKLLLTAIGYGHVRAVAEACQPGVEGVNPMTQINQVTHDQAVVLQ 1199

Query: 1201 SALQSIPNPSSECVLRNESILLAQEISNEASRYMPDICVIRAIQKIIWASACGALGLVFS 1260
            SALQSIPNPSSEC+LRN S+ LAQ+IS+EASRYMPDICVIRAIQKIIWAS CG+L LVFS
Sbjct: 1200 SALQSIPNPSSECMLRNVSVRLAQQISDEASRYMPDICVIRAIQKIIWASGCGSLQLVFS 1259

Query: 1261 PNEEITKIYQMTTNGSNKLEVEDEQVCCEALEVMTLCFALLPTALDALSKEKAWQTFIID 1320
            PNEEITKIY+  TN  N+ ++EDEQVCCEALEVMTLCFAL+PTALDALSKEKAWQTFIID
Sbjct: 1260 PNEEITKIYE-KTNAGNEPDLEDEQVCCEALEVMTLCFALIPTALDALSKEKAWQTFIID 1318

Query: 1321 LLLHCPSKTVRQLAQEQFFLMCTRCCMGHRPLLFFITLLFTILGSTAREKGKYSGDYFTL 1380
            LLLHC SKTVRQ+AQEQFFLMCTRCCMGHRPLLFFITLLFT+LGSTARE+ K+SGDYFTL
Sbjct: 1319 LLLHCHSKTVRQVAQEQFFLMCTRCCMGHRPLLFFITLLFTVLGSTARERAKHSGDYFTL 1378

Query: 1381 LRHLLNYAYNGNINIPNAEVLLVSEIDWLKRIRDNVKNTGETGVEEPILEGHLGVTKELL 1440
            LRHLLNYAYN NIN+PNAEVLL +EIDWLKRIRD+VK TGETG+EE ILEGHLGVTKELL
Sbjct: 1379 LRHLLNYAYNSNINVPNAEVLLNNEIDWLKRIRDDVKRTGETGIEETILEGHLGVTKELL 1438

Query: 1441 AFQTSEKKYHFGCEKGGANLIKELIDDFIFPASKVYLQYLRSGELPAEQAIPVCSSPVTI 1500
            AFQTSEKK+H GCEKGGANLIKELIDDFIFPAS VYLQY+R+GELPAEQAIPVC SP TI
Sbjct: 1439 AFQTSEKKFHIGCEKGGANLIKELIDDFIFPASNVYLQYMRNGELPAEQAIPVCGSPPTI 1498

Query: 1501 NAGFELLVALAIGCVRNLKQIVDCLTEMYYMGTAITTCEALTEWEYLPPVGPRPPKGFVG 1560
            NAGFELLVALA+GCVRNLKQIVD LTEMYY+GTAITTCEALTEWEYLPPVGPRPPKGFVG
Sbjct: 1499 NAGFELLVALAVGCVRNLKQIVDSLTEMYYIGTAITTCEALTEWEYLPPVGPRPPKGFVG 1558

Query: 1561 LKNAGATCYMNSVIQQLYMIPSIRNSILAIEGTGSDLHDDMFGDEKQDSESNVDPRDDVF 1620
            LKNAGATCYMNSVIQQLYMIPSIRN ILAIEGTGSD+ DDM GDEKQD+ESNVDPRDDVF
Sbjct: 1559 LKNAGATCYMNSVIQQLYMIPSIRNGILAIEGTGSDVDDDMSGDEKQDNESNVDPRDDVF 1618

Query: 1621 GYPHQFEDKPALSKTEDRKEYNIGVLRHLQVIFGHLAASQLQYYVPRGFWKQFRLWGEPV 1680
            GYP QFEDKPALSKTEDRKEYNIGVLRHLQVIFGHLAAS+LQYYVPRGFWKQFRLWGEPV
Sbjct: 1619 GYPQQFEDKPALSKTEDRKEYNIGVLRHLQVIFGHLAASRLQYYVPRGFWKQFRLWGEPV 1678

Query: 1681 NLREQHDALEFFNSLVDSLDEALKALGHPAILSKVLGGSFADQKICQGCPHRYECEESFT 1740
            NLREQHDALEFFNSLVDSLDEALKALGHPA+LSKVLGGSFADQKICQGCPHRYECEESFT
Sbjct: 1679 NLREQHDALEFFNSLVDSLDEALKALGHPAMLSKVLGGSFADQKICQGCPHRYECEESFT 1738

Query: 1741 TLNVDIRNHQNLLDSLEQYIKGDLLEGANAYHCEKCDKKVDTVKRLLIKKLPRVLAIQLK 1800
            TLNVDIRNHQNLLDSLEQY+KGDLLEGANAYHCEKC+KKVDTVKRLLIKKLP VLAIQLK
Sbjct: 1739 TLNVDIRNHQNLLDSLEQYVKGDLLEGANAYHCEKCNKKVDTVKRLLIKKLPPVLAIQLK 1798

Query: 1801 RFDYDWERECAIKFNDYFEFPRELDMGPYTVAGVANLERDNVNSENELIEQKEQSDNETA 1860
            RFDYDWERECAIKFNDYFEFPRELDM PYTVAGVA LE DNVN E++LI+Q EQS++ETA
Sbjct: 1799 RFDYDWERECAIKFNDYFEFPRELDMEPYTVAGVAKLEGDNVNPESQLIQQSEQSESETA 1858

Query: 1861 GGTKYRLVGVLVHSGQASGGHYYSYIIQRNGKDDQTDHWYKFDDGDVTECKMDDDEEMKN 1920
            G TKYRLVGVLVHSGQASGGHYYSYIIQRNG D + + WYKFDDGDVTECKMDDDEEMKN
Sbjct: 1859 GSTKYRLVGVLVHSGQASGGHYYSYIIQRNGGDGERNRWYKFDDGDVTECKMDDDEEMKN 1918

Query: 1921 QCFGGEYMGEVFDHMMKRMSYRRQKRWWNAYILFYEQMDMIDEDDEMIRYISELTI-ARP 1979
            QCFGGEYMGEVFDHMMKRMSYRRQKRWWNAYILFYE+MD ID+DDE+IRYISEL I  RP
Sbjct: 1919 QCFGGEYMGEVFDHMMKRMSYRRQKRWWNAYILFYERMDTIDQDDELIRYISELAITTRP 1978

Query: 1980 HQIIMSPAIERSVRKQNVKFMHNRLQYSLEYFQFVKKLLTCNGVYLNPAPGQDYLLPEAE 2039
            HQIIM  AIERSVRKQNV+FMHNR+QYS+EYFQF+KKLLTCNGVYLNP PGQD+LLPEAE
Sbjct: 1979 HQIIMPSAIERSVRKQNVQFMHNRMQYSMEYFQFMKKLLTCNGVYLNPPPGQDHLLPEAE 2038

Query: 2040 EITMISIQLAARFLFTTGFHTKKIVRGPASDWYDALCVLLRHSKNVRFWFTHNVLFNVSN 2099
            EITMISIQLAARFLFTTGFHTKK+VRG ASDWYDALC+LLRHSKNVRFWF HNVLFNVSN
Sbjct: 2039 EITMISIQLAARFLFTTGFHTKKVVRGSASDWYDALCILLRHSKNVRFWFAHNVLFNVSN 2098

Query: 2100 RFSEYLLECPSAEVRGAFAKLIVFIAHFSLQDGSCPSPFASPGPSSQACDNLSLSDHLLR 2159
            RFSEYLLECPSAEVRGAFAKLIVFIAHFSLQDG CPSPFASPGPSSQA DNLSLSDHLLR
Sbjct: 2099 RFSEYLLECPSAEVRGAFAKLIVFIAHFSLQDGPCPSPFASPGPSSQAYDNLSLSDHLLR 2158

Query: 2160 ATLNLLRREVSEHGHHLQQYFNLFVMYANLGVAEKTQLLKLNVPATFMLVSLDEGPGPPI 2219
            A LNLLRREVSEHG HLQQYFNLFVMYANLGVAEKTQLLKL+VPATFMLVSLDEGPGPPI
Sbjct: 2159 AVLNLLRREVSEHGRHLQQYFNLFVMYANLGVAEKTQLLKLSVPATFMLVSLDEGPGPPI 2218

Query: 2220 KYQYAELGKLYSVVSQLIRCCNVSSTMQSSINGNPPLPNPFGDLNLSQPIMPIQQNVLDI 2279
            KYQYAELGKLYSVVSQLIRCCNVSS MQSSINGNPPLPNPFGD NLSQPIMPIQQNV DI
Sbjct: 2219 KYQYAELGKLYSVVSQLIRCCNVSSRMQSSINGNPPLPNPFGDPNLSQPIMPIQQNVADI 2278

Query: 2280 LFVRTSYVKKIIEDCSNSEDTIKLLRFCSWENPQFSSTVLSELLWQVAYSYTYELRPYLD 2339
            LFVRTSYVKKIIEDCSNSE+T+KLLRFC WENPQFSSTVLSELLWQVAYSYTYELRPYLD
Sbjct: 2279 LFVRTSYVKKIIEDCSNSEETVKLLRFCCWENPQFSSTVLSELLWQVAYSYTYELRPYLD 2338

Query: 2340 LLFQILLIEDSWQTHRIHNALKGIPDDRDGLFDTIQRSKNHYQKRAYQCIKCMVALFSSC 2399
            LL QILLIEDSWQTHRIHNALKGIPDDRDGLFDTIQRSKNHYQKRAYQCIKCMVALFS+C
Sbjct: 2339 LLLQILLIEDSWQTHRIHNALKGIPDDRDGLFDTIQRSKNHYQKRAYQCIKCMVALFSNC 2398

Query: 2400 PVAYQILQGNGDLKRKWTWAVEWLGDELERRPYTGNPQYSYNNWSPPVQSNETANGYFLE 2459
            PVAYQILQGNGDLKRKWTWAVEWLGDELERRPYTGNPQY+YNNWSPPVQSNET+NGYFLE
Sbjct: 2399 PVAYQILQGNGDLKRKWTWAVEWLGDELERRPYTGNPQYTYNNWSPPVQSNETSNGYFLE 2458

Query: 2460 RSHSARMTLAKACELCPEE----------------EPDDQDAPDEHEPSPSEDAPLYPHS 2503
            RSHSARMTLAKACELCPEE                EPDDQDAPDEHE  P EDAPLYPHS
Sbjct: 2459 RSHSARMTLAKACELCPEEVKKATSVQQIEMEESKEPDDQDAPDEHESPPPEDAPLYPHS 2518

Query: 2504 PASQYQQNNHVHGQPYTGPAAHHLNNPQKTGQRTQENYEGNEEVSSPQMKDQ 2555
            P SQYQQNNHVHGQPYTGPAAHH+NNPQ+TGQR QENYEG+EEVS PQ KDQ
Sbjct: 2519 PGSQYQQNNHVHGQPYTGPAAHHMNNPQRTGQRAQENYEGSEEVSPPQTKDQ 2570


>gi|149192845 ubiquitin specific protease 24 [Homo sapiens]
          Length = 2460

 Score =  942 bits (2434), Expect = 0.0
 Identities = 758/2574 (29%), Positives = 1202/2574 (46%), Gaps = 385/2574 (14%)

Query: 109  GLDVKSEACQRFFRDGLTISFTKILMDEAVSGWKFEIHRCIINNTHRLVELCVAKLSQDW 168
            GL    E C+RF    +  +F K+L   AV  W  EIH  I N    L+EL   ++ QD 
Sbjct: 52   GLSESDENCRRFMDRCMPEAFKKLLTSSAVHKWGTEIHEGIYNMLMLLIELVAERIKQDP 111

Query: 169  FP--LLELLAMALNPHCKFHIYNGTRPCELISSNAQLPEDELFARS---SDPRSPKGWLV 223
             P  LL +L MA NP  ++H  N  +  +   +     E  +FA S   +  + P GW+V
Sbjct: 112  IPTGLLGVLTMAFNPDNEYHFKNRMKVSQRNWAEV-FGEGNMFAVSPVSTFQKEPHGWVV 170

Query: 224  DLINKFGTLNGFQILHDRFFNGSALNIQIIAALIKPFGQCYEFLSQHTLKKYFIPVIEIV 283
            DL+NKFG L GF  +  +  +   + +  ++ALI+P G C E+L+   ++    PVI   
Sbjct: 171  DLVNKFGELGGFAAIQAKL-HSEDIELGAVSALIQPLGVCAEYLNSSVVQPMLDPVILTT 229

Query: 284  PHLLENLTDEELKKEAKNEAKNDALSMIIKSLKNLASRISGQDETIKNLEIFRLKMILRL 343
               + ++ +++LK     + +  ++  ++ ++K L  R   Q + +  ++  RL ++LR+
Sbjct: 230  IQDVRSVEEKDLK-----DKRLVSIPELLSAVKLLCMRF--QPDLVTIVDDLRLDILLRM 282

Query: 344  LQISSFNGKMNALNEINKVISSVSYYTHRHSNPEEEEWLTAERMAEWIQQNNILSIVLQD 403
            L+   F+ KMN+L E+ K+I   +       +   +  +  +R+ +W+ +N++LSI L+ 
Sbjct: 283  LKSPHFSAKMNSLKEVTKLIEDSTL------SKSVKNAIDTDRLLDWLVENSVLSIALEG 336

Query: 404  SLHQPQYVEKLEKILRFVIKEKALTLQDLDNIWAAQAGKHEAIVKNVHDLLAKLAWDFSP 463
            ++ Q QY ++++ I+  +  +  L+L +L  IW  Q+G+   +++N+H ++A  A  F+ 
Sbjct: 337  NIDQAQYCDRIKGIIELLGSK--LSLDELTKIWKIQSGQSSTVIENIHTIIAAAAVKFNS 394

Query: 464  GQLDHLFDCFKASWTNASKKQREKLLELIRRLAEDDKDGVMAHKVLNLLWNLAQSDDVPV 523
             QL+HLF                                V+  KVL++LW LA    +P 
Sbjct: 395  DQLNHLF--------------------------------VLIQKVLDVLWELAHLPTLPS 422

Query: 524  DIMDLALSAHIKILDYSCSQDRDAQKIQWIDHFIEELRTNDK-------WVIPALKQIRE 576
             ++  AL  H+ IL  + +  ++A K  +I   IE+++ + +       WV+PAL+Q+ E
Sbjct: 423  SLIQQALEEHLTILSDAYAV-KEAIKRSYIIKCIEDIKRSSQLNNPQFVWVVPALRQLHE 481

Query: 577  ICSLFGEASQNLSQTQRSPHIFYRHDLINQLQQNHALVTLVAENLATYMNSIRLYAGDHE 636
            I   F      + QT +         +I  L++N  +V LV  +L          AG   
Sbjct: 482  ITRSF------IKQTYQKQD----KSIIQDLKKNFEIVKLVTGSLIACHRLAAAVAGPGG 531

Query: 637  DYDPQTVRLGSRYSHVQEVQERLNFLRFLLKDGQLWLCAPQAKQIWKCLAENA-VYLCDR 695
                  V    RY++ + ++  L FL F L++  L+L   +AK+IW+CL     V   DR
Sbjct: 532  LSGSTLV--DGRYTYREYLEAHLKFLAFFLQEATLYLGWNRAKEIWECLVTGQDVCELDR 589

Query: 696  EACFKWYSKLMGDEPDLDPDINKDFFESNVLQLDPSLLTENGMKCFERFFKAVNCRERKL 755
            E CF+W++K    + DL+ D+ +  F+  +L+L+   +T NG   F+ FF+ VN  + +L
Sbjct: 590  EMCFEWFTK---GQHDLESDVQQQLFKEKILKLESYEITMNGFNLFKTFFENVNLCDHRL 646

Query: 756  IAKRRSYMMDDLELIGLDYLWRVVIQSSDE-IANRAIDLLKEI-YTNLGPRLKANQVVIH 813
              +     ++ LELIG+D++W++ ++S DE IAN AI L+    Y NL PRLK + V +H
Sbjct: 647  KRQGAQLYVEKLELIGMDFIWKIAMESPDEEIANEAIQLIINYSYINLNPRLKKDSVSLH 706

Query: 814  EDFIQSCFDRLKASYDTL-------CVFDGDKNSINCARQEAIRMV-------------R 853
            + FI  C+ RL+A+   L        V    K     A       V             R
Sbjct: 707  KKFIADCYTRLEAASSALGGPTLTHAVTRATKMLTATAMPTVATSVQSPYRSTKLVIIER 766

Query: 854  VLTVIKEYINECDSDYHKERMILPMSRAFRGKHLSLIVRFPNQGRQVDELDIWSHTNDTI 913
            +L + + Y+   +  Y   R ILP   +F G  L+L V + +     D   + +H+N+TI
Sbjct: 767  LLLLAERYVITIEDFYSVPRTILPHGASFHGHLLTLNVTYESTK---DTFTVEAHSNETI 823

Query: 914  GSVRRCIVNRIKANVAHKKIELFVGGELIDSEDDRKLIGQLNLKDKSLITAKLTQINFNM 973
            GSVR  I  ++ + V +  I++F    L+    D+KL+ QL   D+ ++T K +      
Sbjct: 824  GSVRWKIAKQLCSPVDN--IQIFTNDSLLTVNKDQKLLHQLGFSDEQILTVKTSGSGTPS 881

Query: 974  PSSPDSSSDSSTASPGNHRNHYNDGPNLEVESCLPGVIMSVHPRYISFLWQVADLGSNLN 1033
             SS DSS+ SS++S G   + Y     +E E  LPGV+M++       L+Q+A    NL 
Sbjct: 882  GSSADSSTSSSSSSSGVFSSSYA----MEQEKSLPGVVMALVCNVFDMLYQLA----NLE 933

Query: 1034 MPPLRDGARVLMKLMPPDRTAVEKL---------------------RAVCLDHAKLGEGK 1072
             P +    R L+ L+P D    E L                     ++  L   +  +  
Sbjct: 934  EPRITLRVRKLLLLIPTDPAIQEALDQLDSLGRKKTLLSESSSQSSKSPSLSSKQQHQPS 993

Query: 1073 LSPPLDSLF--FGPSAS--QVLYLTEVVYALLMPAGVP--LTDGSSDFQVHFLKSGGLPL 1126
             S  L+SLF  F P  S  +VLY  EV+ + LMP          +  F  +FLK+GGL L
Sbjct: 994  ASSILESLFRSFAPGMSTFRVLYNLEVLSSKLMPTADDDMARSCAKSFCENFLKAGGLSL 1053

Query: 1127 VLSMLIRNNFLPNTDMETRRGAYLNALKIAKLLLTAIGYGHVRAVAEACQPVVDGTDPIT 1186
            V++++ R++     D ETR+G Y   L++A+ LL     G             DG + ++
Sbjct: 1054 VVNVMQRDSIPSEVDYETRQGVYSICLQLARFLLV----GQTMPTLLDEDLTKDGIEALS 1109

Query: 1187 QINQVTHDQAVVLQSALQSIPNPSS--------ECVLRNESILLAQEISNEASRYMPDIC 1238
                    +    Q +L   P  SS           +R E I+ A  ++ +         
Sbjct: 1110 SRPFRNVSRQTSRQMSLCGTPEKSSYRQLSVSDRSSIRVEEIIPAARVAIQTMEVSDFTS 1169

Query: 1239 VIRAIQKIIWASACGALGLVFS--PNEEITKIY------QMTTNGSN------------- 1277
             +    ++ WA+A G L LV S  P +E   +       +++++GSN             
Sbjct: 1170 TVACFMRLSWAAAAGRLDLVGSSQPIKESNSLCPAGIRNRLSSSGSNCSSGSEGEPVALH 1229

Query: 1278 --------KLEVEDEQVCCEALEVMTLCFALLPTALDALSKEKAWQTFIIDLLLHCPSKT 1329
                     +  +D  +  EAL ++  C  L    L +         FIID+LL  PS  
Sbjct: 1230 AGICVRQQSVSTKDSLIAGEALSLLVTCLQLRSQQLASFYNLPCVADFIIDILLGSPSAE 1289

Query: 1330 VRQLAQEQFFLMCTRCCMGH----RPLLFFITLLFT----------ILGSTAREKGKYSG 1375
            +R++A +Q + +       H    +P  F + ++ T          I+    +       
Sbjct: 1290 IRRVACDQLYTLSQTDTSAHPDVQKPNQFLLGVILTAQLPLWSPTSIMRGVNQRLLSQCM 1349

Query: 1376 DYFTLLRHLLNYAYNGNINIPNAE--VLLVSEIDWLKRIRDNVKNTGETGVEEPIL-EGH 1432
            +YF L   LL+      +         +L  EI WL     N     ET   + IL  GH
Sbjct: 1350 EYFDLRCQLLDDLTTSEMEQLRISPATMLEDEITWLDNFEPNRTAECETSEADNILLAGH 1409

Query: 1433 LGVTKELLAFQTSEKKYHFGCEKGGANLIKELIDDFIFPASKVYLQY---LRSGELPAEQ 1489
            L + K LL+   +EK      E  G++LIK L+DDF+F AS++ L       S  +  + 
Sbjct: 1410 LRLIKTLLSLCGAEK------EMLGSSLIKPLLDDFLFRASRIILNSHSPAGSAAISQQD 1463

Query: 1490 AIPVCSSPVTINAGFELLVALAIGCVRNLKQIVDCLTEMYYMGTAITTCEALTEWEYLPP 1549
              P CS+  +  A +E+LV LA     NL+ I+  L  M++      T     E++YLPP
Sbjct: 1464 FHPKCSTANSRLAAYEVLVMLADSSPSNLQIIIKELLSMHHQPDPALT----KEFDYLPP 1519

Query: 1550 VGPRPPKGFVGLKNAGATCYMNSVIQQLYMIPSIRNSILAIEGTGSDLHDDMFGDEKQDS 1609
            V  R   GFVGL+N GATCYMN+V QQLYM P +  S+L+++                  
Sbjct: 1520 VDSRSSSGFVGLRNGGATCYMNAVFQQLYMQPGLPESLLSVD------------------ 1561

Query: 1610 ESNVDPRDDVFGYPHQFEDKPALSKTEDRKEYNIGVLRHLQVIFGHLAASQLQYYVPRGF 1669
            +   +P D VF                            +Q +FGHL  S+LQYYVP  F
Sbjct: 1562 DDTDNPDDSVF--------------------------YQVQSLFGHLMESKLQYYVPENF 1595

Query: 1670 WKQFRLWGEPVNLREQHDALEFFNSLVDSLDEALKALGHPAILSKVLGGSFADQKICQGC 1729
            WK F++W + + +REQ DA EFF SL+D +DE LK +G   I      G ++DQKIC+ C
Sbjct: 1596 WKIFKMWNKELYVREQQDAYEFFTSLIDQMDEYLKKMGRDQIFKNTFQGIYSDQKICKDC 1655

Query: 1730 PHRYECEESFTTLNVDIRNHQNLLDSLEQYIKGDLLEGANAYHCEKCDKKVDTVKRLLIK 1789
            PHRYE EE+F  LN+ + + Q+L  SL+Q+++G++LEG+NAY+CEKC +K  TVKR  IK
Sbjct: 1656 PHRYEREEAFMALNLGVTSCQSLEISLDQFVRGEVLEGSNAYYCEKCKEKRITVKRTCIK 1715

Query: 1790 KLPRVLAIQLKRFDYDWERECAIKFNDYFEFPRELDMGPYTVAGVANLERDNVNSENELI 1849
             LP VL I L RF +DWE   +IK+++   FP  L+M PYTV+G+A   R + +SE   +
Sbjct: 1716 SLPSVLVIHLMRFGFDWESGRSIKYDEQIRFPWMLNMEPYTVSGMA---RQDSSSE---V 1769

Query: 1850 EQKEQSDNETAGGT---------KYRLVGVLVHSGQASGGHYYSYIIQRNGKDDQTDHWY 1900
             +  +S ++  GG+          Y LVGV+VHSGQA  GHYYS+I  R G       WY
Sbjct: 1770 GENGRSVDQGGGGSPRKKVALTENYELVGVIVHSGQAHAGHYYSFIKDRRGCG--KGKWY 1827

Query: 1901 KFDDGDVTECKMDDDEEMKNQCFGGEYMGEVFDHMMKRMSYRRQKRWWNAYILFYE---- 1956
            KF+D  + E  + +DE ++ +CFGGEY  +V+D        RR  R+WNAY+LFY+    
Sbjct: 1828 KFNDTVIEEFDL-NDETLEYECFGGEYRPKVYDQTNPYTDVRR--RYWNAYMLFYQRVSD 1884

Query: 1957 ----------QMDMIDEDDEMIRY-------ISELTIARPHQ------------------ 1981
                      ++ ++ ++ E +         IS  +  RPH+                  
Sbjct: 1885 QNSPVLPKKSRVSVVRQEAEDLSLSAPSSPEISPQSSPRPHRPNNDRLSILTKLVKKGEK 1944

Query: 1982 ----IIMSPA-IERSVRKQNVKFMHNRLQYSLEYFQFVKKLLTCNGVYLNPAPGQDYLLP 2036
                +   PA I + VR +N+KFM NR  YS +YF FV  L + N   L          P
Sbjct: 1945 KGLFVEKMPARIYQMVRDENLKFMKNRDVYSSDYFSFVLSLASLNATKLKH--------P 1996

Query: 2037 EAEEITMISIQLAARFLFTTGFHTKKIVRGPASDWYDALCVLLRHSKNVRFWFTHNVLFN 2096
                +  +S+QLA +FLF T   TKK +R    +W   +  LL  S +   W     + +
Sbjct: 1997 YYPCMAKVSLQLAIQFLFQTYLRTKKKLRVDTEEWIATIEALLSKSFDACQWLVEYFISS 2056

Query: 2097 VSNRFSE-YLLECPSAEVRGAFAKLIVFIAHFSLQDGSCPSPFASPGPSSQACDNLSLSD 2155
                  + +LLEC   EVR A A ++      +L        F          D L    
Sbjct: 2057 EGRELIKIFLLECNVREVRVAVATILEKTLDSAL--------FYQ--------DKLKSLH 2100

Query: 2156 HLLRATLNLLRREVSEHGHHLQQYFNLFVMYANLGVAEKTQLLKLNVPATFMLVSLDEGP 2215
             LL   L LL ++V E+  +  QYF LF  +          LL L   A   ++S   G 
Sbjct: 2101 QLLEVLLALLDKDVPENCKNCAQYFFLFNTFVQKQGIRAGDLL-LRHSALRHMISFLLGA 2159

Query: 2216 GPP-------IKYQYAELGKLYSVVSQLIRCCNVSSTMQSS---INGNPPLPNPFGDLNL 2265
                         Q  E G L++ V+ L+   +VSS    +       PP+      +  
Sbjct: 2160 SRQNNQIRRWSSAQAREFGNLHNTVALLVLHSDVSSQRNVAPGIFKQRPPI-----SIAP 2214

Query: 2266 SQPIMPIQQNVLDILFVRTS--YVKKII----EDCSNSEDTIKLLRFCSWENPQFSSTVL 2319
            S P++P+ + V  +LF+     Y+ +++    E   +    I+++ +C + N  FS T+L
Sbjct: 2215 SSPLLPLHEEVEALLFMSEGKPYLLEVMFALRELTGSLLALIEMVVYCCFCNEHFSFTML 2274

Query: 2320 SELLWQVAYSYTYELRPYLDLLFQILLIEDSWQTHRIHNALKGIPDDRDGLFDTIQRSKN 2379
              +  Q+  +  +EL+    LL +IL+IED  Q  R+    K + +  +GL   +  S +
Sbjct: 2275 HFIKNQLETAPPHELKNTFQLLHEILVIEDPIQVERV----KFVFETENGLLALMHHSNH 2330

Query: 2380 HYQKRAYQCIKCMVALFSSCPVAYQILQGNGDLKRKWTWAVEWLGDELERRPYTGNPQYS 2439
                R YQC+K +V L   CP A +  + N      W+WAV+WL  ++           S
Sbjct: 2331 VDSSRCYQCVKFLVTLAQKCPAAKEYFKEN---SHHWSWAVQWLQKKM-----------S 2376

Query: 2440 YNNWSPPVQ-SNETANGYFLERSHSARMTLAKACELCPEEEPDDQDAPDEHEPS 2492
             + W+P    SNET+ G   +R+ SA+ TLA A  L  E+E        E  P+
Sbjct: 2377 EHYWTPQSNVSNETSTGKTFQRTISAQDTLAYATALLNEKEQSGSSNGSESSPA 2430


>gi|110347427 ubiquitin specific protease 34 [Homo sapiens]
          Length = 3546

 Score =  256 bits (655), Expect = 2e-67
 Identities = 223/850 (26%), Positives = 371/850 (43%), Gaps = 130/850 (15%)

Query: 1376 DYFTLLRHLLNYAYNGNINIPNAEVLLVSEIDWLKR-----IRDN-VKNTGETGVEEPIL 1429
            +YF LL  L++     NI+I +A    + ++D L R     IR   + +  +  VE+  L
Sbjct: 1733 EYFWLLCKLVD-----NIHIKDASQTTLLDLDALARHLADCIRSREILDHQDGNVEDDGL 1787

Query: 1430 EGHLGVTKELLAFQTSEKKYHFGCEKGGANLIKELIDD-FIFPASKVYLQYLRSGELPAE 1488
             G L      LA    + K  F   + G   ++++ +  F+ P+ K             +
Sbjct: 1788 TGLLR-----LATSVVKHKPPFKFSREGQEFLRDIFNLLFLLPSLK-------------D 1829

Query: 1489 QAIPVCSSPVTINAGFELLVALAIGCVRNLKQIVDCLTEMYYMGTAITTCEALTEWEYLP 1548
            +  P C S  +  A ++LLV +  G V N + I + +   +          A  +W+Y P
Sbjct: 1830 RQQPKCKSHSSRAAAYDLLVEMVKGSVENYRLIHNWVMAQHMQS------HAPYKWDYWP 1883

Query: 1549 PVGPRPPKGFVGLKNAGATCYMNSVIQQLYMIPSIRNSILAIEGTGSDLHDDMFGDEKQD 1608
                R    FVGL N GATCY+ S IQQLYMIP  R ++   +                 
Sbjct: 1884 HEDVRAECRFVGLTNLGATCYLASTIQQLYMIPEARQAVFTAK----------------- 1926

Query: 1609 SESNVDPRDDVFGYPHQFEDKPALSKTEDRKEYNIGVLRHLQVIFGHLAASQLQYYVPRG 1668
                                      +ED K      L  LQ +F +L  S+ + Y PR 
Sbjct: 1927 -------------------------YSEDMKHKT--TLLELQKMFTYLMESECKAYNPRP 1959

Query: 1669 FWKQFRLWGEPVNLREQHDALEFFNSLVDSLDEALKALGHPAILSKVLGGSFADQKICQG 1728
            F K + +  +P+N  EQ D  EFF  L+  ++E    L +   +  + GG   +  +   
Sbjct: 1960 FCKTYTMDKQPLNTGEQKDMTEFFTDLITKIEEMSPELKNT--VKSLFGGVITNNVVSLD 2017

Query: 1729 CPHRYECEESFTTLNVDIRNHQNLLDSLEQYIKGDLLEGANAYHCEKCDKKVDTVKRLLI 1788
            C H  +  E F T+   + + +N+ +SL++    D LEG N Y C  C KKV   KR   
Sbjct: 2018 CEHVSQTAEEFYTVRCQVADMKNIYESLDEVTIKDTLEGDNMYTCSHCGKKVRAEKRACF 2077

Query: 1789 KKLPRVLAIQLKRFDYDWERECAIKFNDYFEFPRELDMGPYTVAGVANLERDNVNSENEL 1848
            KKLPR+L+    R+ ++       K N +F FP  LDM PYT         D +  ++E 
Sbjct: 2078 KKLPRILSFNTMRYTFNMVTMMKEKVNTHFSFPLRLDMTPYT--------EDFLMGKSER 2129

Query: 1849 IEQ-KEQSD-NETAGGTKYRLVGVLVHSGQASGGHYYSYIIQ-RNGKDDQTDHWYKFDDG 1905
             E  KE SD ++ +   +Y L+GV VH+G A GGHYYS+I    N    + + WY F+D 
Sbjct: 2130 KEGFKEVSDHSKDSESYEYDLIGVTVHTGTADGGHYYSFIRDIVNPHAYKNNKWYLFNDA 2189

Query: 1906 DVTECKMDDDEEMKNQCFGGEYMGEVFDHMMKRMSYRRQKRWWNAYILFYEQMDMIDEDD 1965
            +V   K  D  ++ ++CFGGE   + +D +  +      ++  +AY+LFY++M+  +E+ 
Sbjct: 2190 EV---KPFDSAQLASECFGGEMTTKTYDSVTDKFMDFSFEKTHSAYMLFYKRMEPEEEN- 2245

Query: 1966 EMIRYISELTIARPHQIIMSPAIERSVRKQNVKFMHNRLQYSLEYFQFVKKLLTCNGVYL 2025
                        R ++  +S  +   +   N++F+ ++  +   YF F+ +L +C     
Sbjct: 2246 -----------GREYKFDVSSELLEWIWHDNMQFLQDKNIFEHTYFGFMWQLCSC----- 2289

Query: 2026 NPAPGQDYLLPEAEEITMISIQLAARFLFTTGFHTKKIVRGPASDWYDALCVLLRHSKNV 2085
               P     LP+ + +++++ +L+  F+  T  H+K+  +     W + L     +S+  
Sbjct: 2290 --IPS---TLPDPKAVSLMTAKLSTSFVLETFIHSKE--KPTMLQWIELLTKQFNNSQAA 2342

Query: 2086 RFWFTHNVLFNVSNRFSEYLLECPSAEVRGAFAKLIVFI--------AHFSLQDGSCPSP 2137
              WF    + +      + L++CP+  VR  F +L + +        AH  LQ G     
Sbjct: 2343 CEWFLDR-MADDDWWPMQILIKCPNQIVRQMFQRLCIHVIQRLRPVHAHLYLQPG-MEDG 2400

Query: 2138 FASPGPSSQACDNLSLSDHLLRATLNLLRREVSEHGHHLQQYFNLFVMYANLGVAEKTQL 2197
                  S +     S     +R  L ++   V  H  HL +YF     +A +G  E   L
Sbjct: 2401 SDDMDTSVEDIGGRSCVTRFVRTLLLIMEHGVKPHSKHLTEYFAFLYEFAKMGEEESQFL 2460

Query: 2198 LKLNVPATFM 2207
            L L   +T +
Sbjct: 2461 LSLQAISTMV 2470



 Score = 65.9 bits (159), Expect = 5e-10
 Identities = 80/321 (24%), Positives = 137/321 (42%), Gaps = 33/321 (10%)

Query: 159 LCVAKLSQDWFPLLELLAMALNPHCKFHIYNGTRPCELISSNAQLPEDELFARSSDPRSP 218
           LCVAK+ Q  FPL    A   N H      + T+   ++ +         F   +D   P
Sbjct: 159 LCVAKIFQIQFPLYT--AYKHNTHPTIEDIS-TQESNILGA---------FCDMNDVEVP 206

Query: 219 KGWLVDLINKFGTLNGFQILHDRFFNGS--ALNIQIIAALIKPFGQCYEFLSQHTLKKYF 276
              L+  +  F   NG  ++ D F  G+   L   I  A I        +L    + ++ 
Sbjct: 207 LH-LLRYVCLFCGKNGLSLMKDCFEYGTPETLPFLIAHAFITVVSNIRIWLHIPAVMQHI 265

Query: 277 IPVIEIVPHLLENLTDEELKKEAKNEAKNDALSMIIKSLKNLASRISGQDETIKNLEIFR 336
           IP    V   L  L+D+EL++ A   A+N A  M     + L + +    E++     + 
Sbjct: 266 IPFRTYVIRYLCKLSDQELRQSA---ARNMADLMWSTVKEPLDTTLCFDKESLDLAFKYF 322

Query: 337 LK--MILRLLQISSFNGKMNALNEINKVISSVSYYTHRHSNPEEEEWLTAERMAEWIQQN 394
           +   + +RL  +S    +++  N++    S VS          + E   A+ +A+W+  N
Sbjct: 323 MSPTLTMRLAGLSQITNQLHTFNDVCNNESLVS----------DTETSIAKELADWLISN 372

Query: 395 NILSIVLQDSLHQPQYVEKLEKILRFVIKEKALTLQDLDNIWAAQAGKHEAIVKNVHDLL 454
           N++  +   +LH  + +++ + IL F+  E  L+ Q +D IWAA   KH    + +HDL 
Sbjct: 373 NVVEHIFGPNLH-IEIIKQCQVILNFLAAEGRLSTQHIDCIWAAAQLKH--CSRYIHDLF 429

Query: 455 AKLAWDFSPGQLDHLFDCFKA 475
             L  +  P  L HL +   A
Sbjct: 430 PSLIKNLDPVPLRHLLNLVSA 450



 Score = 60.5 bits (145), Expect = 2e-08
 Identities = 74/328 (22%), Positives = 135/328 (41%), Gaps = 43/328 (13%)

Query: 511  LLWNLAQSDDVPVDIMDLALSAHIKILDYSCSQDRDAQ-KIQWIDHFIEELRTNDKWVIP 569
            LLW++ Q +D  V++ +  ++   K+L        D Q ++++I+  +E L  N   VI 
Sbjct: 862  LLWDIVQDEDA-VNLSEGLINEAEKLLCSLVCWFTDRQIRMRFIEGCLENLGNNRSVVI- 919

Query: 570  ALKQIREICSLFGEASQNLSQTQRSPHIFYRHDLINQLQQNHALVTLVAENLATYMNSIR 629
                +R +  LFG   Q  S        +  H +    ++   ++ L  +NL  Y+ ++R
Sbjct: 920  ---SLRLLPKLFGTFQQFGSS-------YDTHWITMWAEKELNMMKLFFDNLVYYIQTVR 969

Query: 630  LYAGDHEDYDPQTVRLGSRYSHVQEVQERLNFLRFLL----KDGQLWLCAPQAKQIWKCL 685
                 H           + YSH  EVQ RL FL  +           L   Q   +W CL
Sbjct: 970  EGRQKH-----------ALYSHSAEVQVRLQFLTCVFSTLGSPDHFRLSLEQVDILWHCL 1018

Query: 686  AENAVYLCDREACFKWYSKLMG-DEPDLDPDINKDFFESNVLQLDPSLLTENGMKCFERF 744
             E++   C  +A   + +++   D+  +  +  K  F   + QL P  ++  G+  F+  
Sbjct: 1019 VEDSE--CYDDALHWFLNQVRSKDQHAMGMETYKHLFLEKMPQLKPETISMTGLNLFQHL 1076

Query: 745  FKAVNCRERKLIAKRRSYMMDDLELIGLDYLWRVVIQS-SDEIANRAIDLLKEIYTNLGP 803
                 C   +L         +  EL G+D  W + +++ S +++  AI  +   Y N   
Sbjct: 1077 -----CNLARLATSAYDGCSNS-ELCGMDQFWGIALRAQSGDVSRAAIQYINSYYINGKT 1130

Query: 804  RLKANQVVIHEDFIQSCFDRLKASYDTL 831
             L+  Q     +FI  C + L  +  +L
Sbjct: 1131 GLEKEQ-----EFISKCMESLMIASSSL 1153


>gi|52630449 ubiquitin specific protease 48 isoform a [Homo sapiens]
          Length = 1035

 Score =  140 bits (353), Expect = 2e-32
 Identities = 121/481 (25%), Positives = 199/481 (41%), Gaps = 93/481 (19%)

Query: 1553 RPPKGFVGLKNAGATCYMNSVIQQLYMIPSIRNSILAIEGTGSDLHDDMFGDEKQDSESN 1612
            R    FVGL N GATCY+N+ +Q  ++   +R ++     T SD    M GD  Q+ E +
Sbjct: 83   RKKNSFVGLTNLGATCYVNTFLQVWFLNLELRQALYLCPSTCSDY---MLGDGIQE-EKD 138

Query: 1613 VDPRDDVFGYPHQFEDKPALSKTEDRKEYNIGVLRHLQVIFGHLAASQLQYYVPRGFWKQ 1672
             +P+                            +  HLQ +F  L  S  +Y  P GF K 
Sbjct: 139  YEPQT---------------------------ICEHLQYLFALLQNSNRRYIDPSGFVKA 171

Query: 1673 FRLWGEPVNLREQHDALEFFNSLVDSLDEALKALGHPA---ILSKVLGGSFADQKICQGC 1729
              L     +  +Q DA EF    +  L++ L    +P    I+ +   G +A   +C  C
Sbjct: 172  LGL-----DTGQQQDAQEFSKLFMSLLEDTLSKQKNPDVRNIVQQQFCGEYAYVTVCNQC 226

Query: 1730 PHRYECEESFTTLNVDIRNHQNLLDSLEQYIKGDLLEGANAYHCEKCDKKVDTVKRLLIK 1789
                +    F  L ++I+ H+ L D + +++K + LEG N Y CE C  K +  +++ + 
Sbjct: 227  GRESKLLSKFYELELNIQGHKQLTDCISEFLKEEKLEGDNRYFCENCQSKQNATRKIRLL 286

Query: 1790 KLPRVLAIQLKRFDYDWERECAIKFNDYFEFPRELDMGPYTVAGVANLERDNVNSENELI 1849
             LP  L +QL RF +D +     K N Y  F   LDM PY                   +
Sbjct: 287  SLPCTLNLQLMRFVFDRQTGHKKKLNTYIGFSEILDMEPY-------------------V 327

Query: 1850 EQKEQSDNETAGGTKYRLVGVLVHSG-QASGGHYYSYIIQRNGKDDQTDHWYKFDDGDVT 1908
            E K        G   Y L  VL+H G  A  GHY +++     KD Q+  WYKF+D D+ 
Sbjct: 328  EHK-------GGSYVYELSAVLIHRGVSAYSGHYIAHV-----KDPQSGEWYKFNDEDIE 375

Query: 1909 ECK-------MDDD-------EEMKNQCFGGEYMGEVFDHMMKRMSYRRQKRWWNAYILF 1954
            + +       +++D       +  K +C  G +       ++ R+  + +         F
Sbjct: 376  KMEGKKLQLGIEEDLAEPSKSQTRKPKCGKGTHCSRNAYMLVYRLQTQEKPNTTVQVPAF 435

Query: 1955 YEQMDMIDEDDEMI-RYISELTIARPHQIIMSPAIERSVRKQNVKFMHNRLQYSLEYFQF 2013
             +  +++D D+     +  E+   R   +    A     + + VK ++ RL    E ++F
Sbjct: 436  LQ--ELVDRDNSKFEEWCIEMAEMRKQSVDKGKA-----KHEEVKELYQRLPAGAEPYEF 488

Query: 2014 V 2014
            V
Sbjct: 489  V 489


>gi|76257392 ubiquitin specific protease 48 isoform b [Homo sapiens]
          Length = 485

 Score =  140 bits (352), Expect = 2e-32
 Identities = 103/359 (28%), Positives = 154/359 (42%), Gaps = 71/359 (19%)

Query: 1553 RPPKGFVGLKNAGATCYMNSVIQQLYMIPSIRNSILAIEGTGSDLHDDMFGDEKQDSESN 1612
            R    FVGL N GATCY+N+ +Q  ++   +R ++     T SD    M GD  Q+ E +
Sbjct: 83   RKKNSFVGLTNLGATCYVNTFLQVWFLNLELRQALYLCPSTCSDY---MLGDGIQE-EKD 138

Query: 1613 VDPRDDVFGYPHQFEDKPALSKTEDRKEYNIGVLRHLQVIFGHLAASQLQYYVPRGFWKQ 1672
             +P+                            +  HLQ +F  L  S  +Y  P GF K 
Sbjct: 139  YEPQT---------------------------ICEHLQYLFALLQNSNRRYIDPSGFVKA 171

Query: 1673 FRLWGEPVNLREQHDALEFFNSLVDSLDEALKALGHPA---ILSKVLGGSFADQKICQGC 1729
              L     +  +Q DA EF    +  L++ L    +P    I+ +   G +A   +C  C
Sbjct: 172  LGL-----DTGQQQDAQEFSKLFMSLLEDTLSKQKNPDVRNIVQQQFCGEYAYVTVCNQC 226

Query: 1730 PHRYECEESFTTLNVDIRNHQNLLDSLEQYIKGDLLEGANAYHCEKCDKKVDTVKRLLIK 1789
                +    F  L ++I+ H+ L D + +++K + LEG N Y CE C  K +  +++ + 
Sbjct: 227  GRESKLLSKFYELELNIQGHKQLTDCISEFLKEEKLEGDNRYFCENCQSKQNATRKIRLL 286

Query: 1790 KLPRVLAIQLKRFDYDWERECAIKFNDYFEFPRELDMGPYTVAGVANLERDNVNSENELI 1849
             LP  L +QL RF +D +     K N Y  F   LDM PY                   +
Sbjct: 287  SLPCTLNLQLMRFVFDRQTGHKKKLNTYIGFSEILDMEPY-------------------V 327

Query: 1850 EQKEQSDNETAGGTKYRLVGVLVHSG-QASGGHYYSYIIQRNGKDDQTDHWYKFDDGDV 1907
            E K        G   Y L  VL+H G  A  GHY +++     KD Q+  WYKF+D D+
Sbjct: 328  EHK-------GGSYVYELSAVLIHRGVSAYSGHYIAHV-----KDPQSGEWYKFNDEDI 374


>gi|71774197 ubiquitin specific protease 47 [Homo sapiens]
          Length = 1287

 Score =  138 bits (347), Expect = 8e-32
 Identities = 136/532 (25%), Positives = 208/532 (39%), Gaps = 114/532 (21%)

Query: 1557 GFVGLKNAGATCYMNSVIQQLYMIPSIRNSILAIEGTGSDLHDDMFGDEKQDSESNVDPR 1616
            G+VGL N   TCY+NS++Q L+M P  RN++   E                  ES  DP 
Sbjct: 98   GYVGLVNQAMTCYLNSLLQTLFMTPEFRNALYKWEF----------------EESEEDP- 140

Query: 1617 DDVFGYPHQFEDKPALSKTEDRKEYNIGVLRHLQVIFGHLAASQLQYYVPRGF-WKQFRL 1675
              V   P+Q +    L +T  ++                         V R F W     
Sbjct: 141  --VTSIPYQLQRLFVLLQTSKKRAIETTD-------------------VTRSFGWDSSEA 179

Query: 1676 WGEPVNLREQHDALEFFNSLVDSLDEALKALGHPAILSKVLGGSFADQKICQGCPHRYEC 1735
            W       +QHD  E    + D+L++  K      +++++  G   D   C  C +    
Sbjct: 180  W-------QQHDVQELCRVMFDALEQKWKQTEQADLINELYQGKLKDYVRCLECGYEGWR 232

Query: 1736 EESFTTLNVDIRNH------QNLLDSLEQYIKGDLLEGANAYHCEKCDKKVDTVKRLLIK 1789
             +++  + + IR +       ++ ++L  +I+ ++L+G N Y CE+C KK D  K L   
Sbjct: 233  IDTYLDIPLVIRPYGSSQAFASVEEALHAFIQPEILDGPNQYFCERCKKKCDARKGLRFL 292

Query: 1790 KLPRVLAIQLKRFDYDWERECAIKFNDYFEFPRELDMGPY-TVAGVANLERDNV---NSE 1845
              P +L +QLKRFD+D+     IK ND   FP ELDM  +  V    + + ++     +E
Sbjct: 293  HFPYLLTLQLKRFDFDYTTMHRIKLNDRMTFPEELDMSTFIDVEDEKSPQTESCTDSGAE 352

Query: 1846 NELIEQKEQSDN--------------ETAGGTK-------------YRLVGVLVHSGQAS 1878
            NE     +Q  N              ET  GT+             Y L  V+VHSG A+
Sbjct: 353  NEGSCHSDQMSNDFSNDDGVDEGICLETNSGTEKISKSGLEKNSLIYELFSVMVHSGSAA 412

Query: 1879 GGHYYSYIIQRNGKDDQTDHWYKFDDGDVTECKMDDDEEMKNQCFGGE-YMGEVFDHMMK 1937
            GGHYY+ I     K    + WY F+D  V+    +D ++      G   Y    F     
Sbjct: 413  GGHYYACI-----KSFSDEQWYSFNDQHVSRITQEDIKKTHGGSSGSRGYYSSAFASST- 466

Query: 1938 RMSYRRQKRWWNAYILFYEQMD--------MIDEDDEMIRYISELTIARPHQIIMSPAIE 1989
                       NAY+L Y   D         +DE  E I+ + +       Q      IE
Sbjct: 467  -----------NAYMLIYRLKDPARNAKFLEVDEYPEHIKNLVQKERELEEQEKRQREIE 515

Query: 1990 RSVRKQNVKFMHNRLQYSLEYFQFVKKLLTCNGVYLNPAPGQDYLLPEAEEI 2041
            R+  K  +  +H   Q  +E      KL       L  A    Y + + EE+
Sbjct: 516  RNTCKIKLFCLHPTKQVMME-----NKLEVHKDKTLKEAVEMAYKMMDLEEV 562


>gi|150378533 ubiquitin specific peptidase 7 [Homo sapiens]
          Length = 1102

 Score =  118 bits (296), Expect = 7e-26
 Identities = 114/442 (25%), Positives = 178/442 (40%), Gaps = 97/442 (21%)

Query: 1557 GFVGLKNAGATCYMNSVIQQLYMIPSIRNSILAIEGTGSDLHDDMFGDEKQDSESNVDPR 1616
            G+VGLKN GATCYMNS++Q L+    +R ++             M   E  DS  +V   
Sbjct: 212  GYVGLKNQGATCYMNSLLQTLFFTNQLRKAVY------------MMPTEGDDSSKSVPLA 259

Query: 1617 DDVFGYPHQFEDKPALSKTEDRKEYNIGVLRHLQVIFGHLAASQLQYYVPRGFWKQFRLW 1676
                 Y  Q  DKP  +K              L   FG                     W
Sbjct: 260  LQRVFYELQHSDKPVGTKK-------------LTKSFG---------------------W 285

Query: 1677 GEPVNLREQHDALEFFNSLVDSLDEALKALGHPAILSKVLGGSFADQKICQGCPHRYECE 1736
             E ++   QHD  E    L+D+++  +K       + K+  G       C+   +R +  
Sbjct: 286  -ETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRR 344

Query: 1737 ESFTTLNVDIRNHQNLLDSLEQYIKGDLLEGANAYHCEKCDKKVDTVKRLLIKKLPRVLA 1796
            E +  + + I+  +N+ +S   Y+  + L+G N Y   +   + +  K +    LP VL 
Sbjct: 345  EDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYDAGEHGLQ-EAEKGVKFLTLPPVLH 403

Query: 1797 IQLKRFDYDWERECAIKFNDYFEFPRELDMGPYTVAGVANLERDNVNSENELIEQKEQSD 1856
            +QL RF YD + +  IK ND FEFP +L +                   +E +++ +  D
Sbjct: 404  LQLMRFMYDPQTDQNIKINDRFEFPEQLPL-------------------DEFLQKTDPKD 444

Query: 1857 NETAGGTKYRLVGVLVHSGQASGGHYYSYIIQRNGKDDQTDHWYKFDDGDVTECKMDDDE 1916
                    Y L  VLVHSG   GGHY  Y+   N K D    W KFDD  V+ C      
Sbjct: 445  -----PANYILHAVLVHSGDNHGGHYVVYL---NPKGD--GKWCKFDDDVVSRC------ 488

Query: 1917 EMKNQCFGGEYMGEVFDHMMKRMSYRRQKRWWNAYILFYEQMDMIDEDDEMIRYISELTI 1976
              K +     Y G   D  ++  +        NAY+L Y +   +    E+++ +++  I
Sbjct: 489  -TKEEAIEHNYGGHDDDLSVRHCT--------NAYMLVYIRESKL---SEVLQAVTDHDI 536

Query: 1977 ARPHQIIMSPAIERSVRKQNVK 1998
              P Q++     E+ +  Q  K
Sbjct: 537  --PQQLVERLQEEKRIEAQKRK 556


>gi|41055953 ubiquitin thioesterase 40 [Homo sapiens]
          Length = 1247

 Score =  114 bits (286), Expect = 9e-25
 Identities = 102/454 (22%), Positives = 183/454 (40%), Gaps = 91/454 (20%)

Query: 1547 LPPVGPRPPKGFVGLKNAGATCYMNSVIQQLYMIPSIRNSILAIEGTGSDLHDDMFGDEK 1606
            L P  PR      G++N G TCY+NS++Q L+  P  R ++ ++      L +D    +K
Sbjct: 41   LEPPAPREFTNLSGIRNQGGTCYLNSLLQTLHFTPEFREALFSLGPEELGLFEDK---DK 97

Query: 1607 QDSESNVDPRDDVFGYPHQFEDKPALSKTEDRKEYNIGVLRHLQVIFGHLAASQLQYYVP 1666
             D++  + P                                 LQ +F  L     +    
Sbjct: 98   PDAKVRIIPLQ-------------------------------LQRLFAQLLLLDQEAAST 126

Query: 1667 RGFWKQFRLWGEPVNLREQHDALEFFNSLVDSLDEALKALGHPAILSKVLGGSFADQKIC 1726
                  F  W     +R QHD  E    L  +L+ +L       ++ ++  G+  +Q +C
Sbjct: 127  ADLTDSFG-WTSNEEMR-QHDVQELNRILFSALETSLVGTSGHDLIYRLYHGTIVNQIVC 184

Query: 1727 QGCPHRYECEESFTTLNVDIRNHQNLLDSL-EQYIKGDLLEGANAYHCEKCDKKVDTVKR 1785
            + C +  E +E F  L V ++N   L D+L   Y++ ++ +  N YHC  CD+ V   K 
Sbjct: 185  KECKNVSERQEDFLDLTVAVKNVSGLEDALWNMYVEEEVFDCDNLYHCGTCDRLVKAAKS 244

Query: 1786 LLIKKLPRVLAIQLKRFDYDWERECAIKFNDYFEFPRELDMGPYTVAGVANLERDNVNSE 1845
              ++KLP  L + L RF++D+ +    K    + FP  +++ P+                
Sbjct: 245  AKLRKLPPFLTVSLLRFNFDFVKCERYKETSCYTFPLRINLKPF---------------- 288

Query: 1846 NELIEQKEQSDNETAGGTKYRLVGVLVHSGQASGGHYYSYIIQRNGKD-DQTDHWYKFDD 1904
                EQ E  D E      Y L  V++H G   GGHY+ YI     KD D   +W   ++
Sbjct: 289  ---CEQSELDDLEYI----YDLFSVIIHKGGCYGGHYHVYI-----KDVDHLGNWQFQEE 336

Query: 1905 ---GDVTECKMDDDEEM-------------KNQCFGGEYMGEVFDHMMKRM------SYR 1942
                DV    +  +EE+             +N     + +G+    ++K++       YR
Sbjct: 337  KSKPDVNLKDLQSEEEIDHPLMILKAILLEENNLIPVDQLGQ---KLLKKIGISWNKKYR 393

Query: 1943 RQKRWWNAYILFYEQMDMIDEDDEMIRYISELTI 1976
            +Q      ++  + Q+ ++  D+  +R +   ++
Sbjct: 394  KQHGPLRKFLQLHSQIFLLSSDESTVRLLKNSSL 427


>gi|239742282 PREDICTED: hypothetical protein XP_002342474 [Homo
            sapiens]
          Length = 530

 Score = 90.9 bits (224), Expect = 1e-17
 Identities = 67/234 (28%), Positives = 103/234 (44%), Gaps = 44/234 (18%)

Query: 1684 EQHDALEFFNSLVDSLDEAL----KALGHPA----ILSKVLGGSFADQKICQGCPHRYEC 1735
            +Q DA EF    VD++ +A     K + HP+    ++ ++ GG +  Q  C  C    + 
Sbjct: 157  KQEDAHEFLMFTVDAMKKACLPGHKQVDHPSKDTTLIHQIFGGYWRSQIKCLHCHGISDT 216

Query: 1736 EESFTTLNVDIRNHQNLLDSLEQYIKGDLLEGANAYHCEKCDKKVDTVKRLLIKKLPRVL 1795
             + +  + +DI+  Q++  +LEQ +K + L G NAYHC  C ++    K L +    +VL
Sbjct: 217  FDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVL 276

Query: 1796 AIQLKRFDYDWERECAIKFNDYFEFPRELDMGPYTVAGVANLERDNVNSENELIEQKEQS 1855
             + LKRF          K     ++P  LDM PY                          
Sbjct: 277  ILVLKRF----SDVTGNKIAKNVQYPECLDMQPY-------------------------M 307

Query: 1856 DNETAGGTKYRLVGVLVHSG-QASGGHYYSYIIQRNGKDDQTDHWYKFDDGDVT 1908
              +  G   Y L  VLVH+G     GHY+SY+  + G+      WYK DD +VT
Sbjct: 308  SQQNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQ------WYKMDDAEVT 355



 Score = 38.5 bits (88), Expect = 0.086
 Identities = 23/73 (31%), Positives = 33/73 (45%)

Query: 1519 KQIVDCLTEMYYMGTAITTCEALTEWEYLPPVGPRPPKGFVGLKNAGATCYMNSVIQQLY 1578
            K  + C T +      +     L   E LP    RP     GL+N G TCY+N+ +Q L 
Sbjct: 40   KSPLSCETRVDLCDDLVPEARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYVNASLQCLT 99

Query: 1579 MIPSIRNSILAIE 1591
              P + N +L+ E
Sbjct: 100  YTPPLANYMLSRE 112


>gi|197116355 ubiquitin specific peptidase 46 isoform 2 [Homo sapiens]
          Length = 359

 Score = 90.1 bits (222), Expect = 2e-17
 Identities = 91/377 (24%), Positives = 143/377 (37%), Gaps = 102/377 (27%)

Query: 1558 FVGLKNAGATCYMNSVIQQLYMIPSIRNSILAIEGTGSDLHDDMFGDEKQDSESNVDPRD 1617
            + GL N G TCY NSV+Q LY     R ++LA                            
Sbjct: 27   YFGLVNFGNTCYCNSVLQALYFCRPFRENVLAY--------------------------- 59

Query: 1618 DVFGYPHQFEDKPALSKTEDRKEYNIGVLRHLQVIFGHLAASQLQYYV--PRGFWKQFRL 1675
                            K + +K+ N+  L  L  +F  +A  + +  V  P+ F  + R 
Sbjct: 60   ----------------KAQQKKKENL--LTCLADLFHSIATQKKKVGVIPPKKFISRLRK 101

Query: 1676 WGEPVNLREQHDALEFFNSLVDSLDEALKA---------------LGHPAILSK------ 1714
              +  +   Q DA EF N L++++ + L+                +  PA  +K      
Sbjct: 102  ENDLFDNYMQQDAHEFLNYLLNTIADILQEEKKQEKQNGKLKNGNMNEPAENNKPELTWV 161

Query: 1715 --VLGGSFADQKICQGCPHRYECEESFTTLNVDIRNHQNLLDSLEQYIKGDLLEGANAYH 1772
              +  G+  ++  C  C      +E F  L+VD+  + ++   L  +   + L     Y+
Sbjct: 162  HEIFQGTLTNETRCLNCETVSSKDEDFLDLSVDVEQNTSITHCLRDFSNTETLCSEQKYY 221

Query: 1773 CEKCDKKVDTVKRLLIKKLPRVLAIQLKRFDYDWERECAIKFNDYFEFPRELDMGPYTVA 1832
            CE C  K +  KR+ +KKLP +LA+ LKRF Y  +     K +    FP EL +      
Sbjct: 222  CETCCSKQEAQKRMRVKKLPMILALHLKRFKYMEQLHRYTKLSYRVVFPLELRL------ 275

Query: 1833 GVANLERDNVNSENELIEQKEQSDNETAGGTKYRLVGVLVHSGQASGGHYYSYIIQRNGK 1892
               N   D VN +                   Y LV V+VH G      +Y  I++ +G 
Sbjct: 276  --FNTSSDAVNLDR-----------------MYDLVAVVVHCGSGPNRGHYITIVKSHG- 315

Query: 1893 DDQTDHWYKFDDGDVTE 1909
                  W  FDD D+ E
Sbjct: 316  -----FWLLFDD-DIVE 326


>gi|31377709 ubiquitin specific peptidase 46 isoform 1 [Homo sapiens]
          Length = 366

 Score = 90.1 bits (222), Expect = 2e-17
 Identities = 91/377 (24%), Positives = 143/377 (37%), Gaps = 102/377 (27%)

Query: 1558 FVGLKNAGATCYMNSVIQQLYMIPSIRNSILAIEGTGSDLHDDMFGDEKQDSESNVDPRD 1617
            + GL N G TCY NSV+Q LY     R ++LA                            
Sbjct: 34   YFGLVNFGNTCYCNSVLQALYFCRPFRENVLAY--------------------------- 66

Query: 1618 DVFGYPHQFEDKPALSKTEDRKEYNIGVLRHLQVIFGHLAASQLQYYV--PRGFWKQFRL 1675
                            K + +K+ N+  L  L  +F  +A  + +  V  P+ F  + R 
Sbjct: 67   ----------------KAQQKKKENL--LTCLADLFHSIATQKKKVGVIPPKKFISRLRK 108

Query: 1676 WGEPVNLREQHDALEFFNSLVDSLDEALKA---------------LGHPAILSK------ 1714
              +  +   Q DA EF N L++++ + L+                +  PA  +K      
Sbjct: 109  ENDLFDNYMQQDAHEFLNYLLNTIADILQEEKKQEKQNGKLKNGNMNEPAENNKPELTWV 168

Query: 1715 --VLGGSFADQKICQGCPHRYECEESFTTLNVDIRNHQNLLDSLEQYIKGDLLEGANAYH 1772
              +  G+  ++  C  C      +E F  L+VD+  + ++   L  +   + L     Y+
Sbjct: 169  HEIFQGTLTNETRCLNCETVSSKDEDFLDLSVDVEQNTSITHCLRDFSNTETLCSEQKYY 228

Query: 1773 CEKCDKKVDTVKRLLIKKLPRVLAIQLKRFDYDWERECAIKFNDYFEFPRELDMGPYTVA 1832
            CE C  K +  KR+ +KKLP +LA+ LKRF Y  +     K +    FP EL +      
Sbjct: 229  CETCCSKQEAQKRMRVKKLPMILALHLKRFKYMEQLHRYTKLSYRVVFPLELRL------ 282

Query: 1833 GVANLERDNVNSENELIEQKEQSDNETAGGTKYRLVGVLVHSGQASGGHYYSYIIQRNGK 1892
               N   D VN +                   Y LV V+VH G      +Y  I++ +G 
Sbjct: 283  --FNTSSDAVNLDR-----------------MYDLVAVVVHCGSGPNRGHYITIVKSHG- 322

Query: 1893 DDQTDHWYKFDDGDVTE 1909
                  W  FDD D+ E
Sbjct: 323  -----FWLLFDD-DIVE 333


>gi|153792150 deubiquitinating enzyme 3 [Homo sapiens]
          Length = 530

 Score = 89.7 bits (221), Expect = 3e-17
 Identities = 67/238 (28%), Positives = 103/238 (43%), Gaps = 44/238 (18%)

Query: 1684 EQHDALEFFNSLVDSLDEAL----KALGHPA----ILSKVLGGSFADQKICQGCPHRYEC 1735
            +Q DA EF    VD++ +A     K + H +    ++ ++ GG +  Q  C  C    + 
Sbjct: 157  KQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGCWRSQIKCLHCHGISDT 216

Query: 1736 EESFTTLNVDIRNHQNLLDSLEQYIKGDLLEGANAYHCEKCDKKVDTVKRLLIKKLPRVL 1795
             + +  + +DI+  Q++  +LEQ +K + L G NAYHC  C ++    K L +    +VL
Sbjct: 217  FDPYLDIALDIQAAQSVKQALEQLVKPEELNGENAYHCGLCLQRAPASKTLTLHTSAKVL 276

Query: 1796 AIQLKRFDYDWERECAIKFNDYFEFPRELDMGPYTVAGVANLERDNVNSENELIEQKEQS 1855
             + LKRF          K     ++P  LDM PY                          
Sbjct: 277  ILVLKRF----SDVTGNKLAKNVQYPECLDMQPY-------------------------M 307

Query: 1856 DNETAGGTKYRLVGVLVHSG-QASGGHYYSYIIQRNGKDDQTDHWYKFDDGDVTECKM 1912
              +  G   Y L  VLVH+G     GHY+SY+  + G+      WYK DD  VT C +
Sbjct: 308  SQQNTGPLVYVLYAVLVHAGWSCHDGHYFSYVKAQEGQ------WYKMDDAKVTACSI 359



 Score = 33.5 bits (75), Expect = 2.8
 Identities = 18/45 (40%), Positives = 24/45 (53%)

Query: 1547 LPPVGPRPPKGFVGLKNAGATCYMNSVIQQLYMIPSIRNSILAIE 1591
            LP    RP     GL+N G TCY N+ +Q L   P + N +L+ E
Sbjct: 68   LPLSSRRPAAVGAGLQNMGNTCYENASLQCLTYTPPLANYMLSRE 112


>gi|190684694 ubiquitin specific peptidase 8 [Homo sapiens]
          Length = 1118

 Score = 89.4 bits (220), Expect = 4e-17
 Identities = 100/397 (25%), Positives = 146/397 (36%), Gaps = 105/397 (26%)

Query: 1547 LPPVGPRPPKGFVGLKNAGATCYMNSVIQQLYMIPSIRNSILAIEGTGSDLHDDMFGDEK 1606
            L PV         GL+N G TCYMNS++Q L   P +                D F    
Sbjct: 765  LNPVFGGSGPALTGLRNLGNTCYMNSILQCLCNAPHLA---------------DYFNRNC 809

Query: 1607 QDSESNVDPRDDVFGYPHQFEDKPALSKTEDRKEYNIGVLRHLQVIFGHLAASQLQYYVP 1666
               + N   R ++ G+           K E  +E+ I        I   L   Q +Y  P
Sbjct: 810  YQDDIN---RSNLLGH-----------KGEVAEEFGI--------IMKALWTGQYRYISP 847

Query: 1667 RGFWKQFRLWGEPVNLREQHDALEFFNSLVDSLDEAL--------------------KAL 1706
            + F        +      Q D+ E    L+D L E L                    KA 
Sbjct: 848  KDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHEDLNKADNRKRYKEENNDHLDDFKAA 907

Query: 1707 GHP---------AILSKVLGGSFADQKICQGCPHRYECEESFTTLNVDIRNHQN--LLDS 1755
             H          +I+  +  G F     C  C  +    E+F  L++ + +     L D 
Sbjct: 908  EHAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKSRTFEAFMYLSLPLASTSKCTLQDC 967

Query: 1756 LEQYIKGDLLEGANAYHCEKCDKKVDTVKRLLIKKLPRVLAIQLKRFDYD--WERECAIK 1813
            L  + K + L   N ++C  C  + D++K++ I KLP VL + LKRF YD  W++    K
Sbjct: 968  LRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLLVHLKRFSYDGRWKQ----K 1023

Query: 1814 FNDYFEFPRE-LDMGPYTVAGVANLERDNVNSENELIEQKEQSDNETAGGTKYRLVGVLV 1872
                 +FP E LD+  Y +    NL+                         KY L  V  
Sbjct: 1024 LQTSVDFPLENLDLSQYVIGPKNNLK-------------------------KYNLFSVSN 1058

Query: 1873 HSGQASGGHYYSYIIQRNGKDDQTDHWYKFDDGDVTE 1909
            H G   GGHY +Y      K+     W+KFDD +V++
Sbjct: 1059 HYGGLDGGHYTAYC-----KNAARQRWFKFDDHEVSD 1090


>gi|190684692 ubiquitin specific peptidase 8 [Homo sapiens]
          Length = 1118

 Score = 89.4 bits (220), Expect = 4e-17
 Identities = 100/397 (25%), Positives = 146/397 (36%), Gaps = 105/397 (26%)

Query: 1547 LPPVGPRPPKGFVGLKNAGATCYMNSVIQQLYMIPSIRNSILAIEGTGSDLHDDMFGDEK 1606
            L PV         GL+N G TCYMNS++Q L   P +                D F    
Sbjct: 765  LNPVFGGSGPALTGLRNLGNTCYMNSILQCLCNAPHLA---------------DYFNRNC 809

Query: 1607 QDSESNVDPRDDVFGYPHQFEDKPALSKTEDRKEYNIGVLRHLQVIFGHLAASQLQYYVP 1666
               + N   R ++ G+           K E  +E+ I        I   L   Q +Y  P
Sbjct: 810  YQDDIN---RSNLLGH-----------KGEVAEEFGI--------IMKALWTGQYRYISP 847

Query: 1667 RGFWKQFRLWGEPVNLREQHDALEFFNSLVDSLDEAL--------------------KAL 1706
            + F        +      Q D+ E    L+D L E L                    KA 
Sbjct: 848  KDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHEDLNKADNRKRYKEENNDHLDDFKAA 907

Query: 1707 GHP---------AILSKVLGGSFADQKICQGCPHRYECEESFTTLNVDIRNHQN--LLDS 1755
             H          +I+  +  G F     C  C  +    E+F  L++ + +     L D 
Sbjct: 908  EHAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKSRTFEAFMYLSLPLASTSKCTLQDC 967

Query: 1756 LEQYIKGDLLEGANAYHCEKCDKKVDTVKRLLIKKLPRVLAIQLKRFDYD--WERECAIK 1813
            L  + K + L   N ++C  C  + D++K++ I KLP VL + LKRF YD  W++    K
Sbjct: 968  LRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLLVHLKRFSYDGRWKQ----K 1023

Query: 1814 FNDYFEFPRE-LDMGPYTVAGVANLERDNVNSENELIEQKEQSDNETAGGTKYRLVGVLV 1872
                 +FP E LD+  Y +    NL+                         KY L  V  
Sbjct: 1024 LQTSVDFPLENLDLSQYVIGPKNNLK-------------------------KYNLFSVSN 1058

Query: 1873 HSGQASGGHYYSYIIQRNGKDDQTDHWYKFDDGDVTE 1909
            H G   GGHY +Y      K+     W+KFDD +V++
Sbjct: 1059 HYGGLDGGHYTAYC-----KNAARQRWFKFDDHEVSD 1090


>gi|190684690 ubiquitin specific peptidase 8 [Homo sapiens]
          Length = 1118

 Score = 89.4 bits (220), Expect = 4e-17
 Identities = 100/397 (25%), Positives = 146/397 (36%), Gaps = 105/397 (26%)

Query: 1547 LPPVGPRPPKGFVGLKNAGATCYMNSVIQQLYMIPSIRNSILAIEGTGSDLHDDMFGDEK 1606
            L PV         GL+N G TCYMNS++Q L   P +                D F    
Sbjct: 765  LNPVFGGSGPALTGLRNLGNTCYMNSILQCLCNAPHLA---------------DYFNRNC 809

Query: 1607 QDSESNVDPRDDVFGYPHQFEDKPALSKTEDRKEYNIGVLRHLQVIFGHLAASQLQYYVP 1666
               + N   R ++ G+           K E  +E+ I        I   L   Q +Y  P
Sbjct: 810  YQDDIN---RSNLLGH-----------KGEVAEEFGI--------IMKALWTGQYRYISP 847

Query: 1667 RGFWKQFRLWGEPVNLREQHDALEFFNSLVDSLDEAL--------------------KAL 1706
            + F        +      Q D+ E    L+D L E L                    KA 
Sbjct: 848  KDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHEDLNKADNRKRYKEENNDHLDDFKAA 907

Query: 1707 GHP---------AILSKVLGGSFADQKICQGCPHRYECEESFTTLNVDIRNHQN--LLDS 1755
             H          +I+  +  G F     C  C  +    E+F  L++ + +     L D 
Sbjct: 908  EHAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKSRTFEAFMYLSLPLASTSKCTLQDC 967

Query: 1756 LEQYIKGDLLEGANAYHCEKCDKKVDTVKRLLIKKLPRVLAIQLKRFDYD--WERECAIK 1813
            L  + K + L   N ++C  C  + D++K++ I KLP VL + LKRF YD  W++    K
Sbjct: 968  LRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLLVHLKRFSYDGRWKQ----K 1023

Query: 1814 FNDYFEFPRE-LDMGPYTVAGVANLERDNVNSENELIEQKEQSDNETAGGTKYRLVGVLV 1872
                 +FP E LD+  Y +    NL+                         KY L  V  
Sbjct: 1024 LQTSVDFPLENLDLSQYVIGPKNNLK-------------------------KYNLFSVSN 1058

Query: 1873 HSGQASGGHYYSYIIQRNGKDDQTDHWYKFDDGDVTE 1909
            H G   GGHY +Y      K+     W+KFDD +V++
Sbjct: 1059 HYGGLDGGHYTAYC-----KNAARQRWFKFDDHEVSD 1090


>gi|122114651 ubiquitin specific peptidase 36 [Homo sapiens]
          Length = 1123

 Score = 88.6 bits (218), Expect = 7e-17
 Identities = 91/373 (24%), Positives = 135/373 (36%), Gaps = 99/373 (26%)

Query: 1544 WEYLPPVGPRPPKGFVGLKNAGATCYMNSVIQQLYMIPSIRNSILAIEGTGSDLHDDMFG 1603
            WE +  VG        GL N G TC++N+ IQ L   P + N +L+ E   S        
Sbjct: 114  WERVFRVG-------AGLHNLGNTCFLNATIQCLTYTPPLANYLLSKEHARSC------- 159

Query: 1604 DEKQDSESNVDPRDDVFGYPHQFEDKPALSKTEDRKEYNIGVLRHLQVIFGHLA---ASQ 1660
                                HQ                  G    L V+  H+    A+ 
Sbjct: 160  --------------------HQ------------------GSFCMLCVMQNHIVQAFANS 181

Query: 1661 LQYYVPRGFWKQFRLWGEPVNLREQHDALEFFNSLVDSLDEAL--------KALGHPAIL 1712
                 P  F +  +          Q DA EF    +D++ +A         +      ++
Sbjct: 182  GNAIKPVSFIRDLKKIARHFRFGNQEDAHEFLRYTIDAMQKACLNGCAKLDRQTQATTLV 241

Query: 1713 SKVLGGSFADQKICQGCPHRYECEESFTTLNVDIRNHQNLLDSLEQYIKGDLLEGANAYH 1772
             ++ GG    +  C  C    +  + +  + ++IR   N++ +LE ++K D+L G NAY 
Sbjct: 242  HQIFGGYLRSRVKCSVCKSVSDTYDPYLDVALEIRQAANIVRALELFVKADVLSGENAYM 301

Query: 1773 CEKCDKKVDTVKRLLIKKLPRVLAIQLKRFDYDWERECAIKFNDYFEFPRELDMGPYTVA 1832
            C KC KKV   KR  I +   VL + LKRF          K      +P  L++ PY   
Sbjct: 302  CAKCKKKVPASKRFTIHRTSNVLTLSLKRF----ANFSGGKITKDVGYPEFLNIRPYM-- 355

Query: 1833 GVANLERDNVNSENELIEQKEQSDNETAGGTKYRLVGVLVHSG-QASGGHYYSYIIQRNG 1891
                       S+N                  Y L  VLVHSG     GHYY Y+   NG
Sbjct: 356  -----------SQN------------NGDPVMYGLYAVLVHSGYSCHAGHYYCYVKASNG 392

Query: 1892 KDDQTDHWYKFDD 1904
            +      WY+ +D
Sbjct: 393  Q------WYQMND 399


>gi|239758075 PREDICTED: similar to deubiquitinating enzyme DUB1 [Homo
            sapiens]
          Length = 530

 Score = 87.4 bits (215), Expect = 2e-16
 Identities = 66/234 (28%), Positives = 102/234 (43%), Gaps = 44/234 (18%)

Query: 1684 EQHDALEFFNSLVDSLDEAL----KALGHPA----ILSKVLGGSFADQKICQGCPHRYEC 1735
            +Q DA EF    VD++ +A     K + H +    ++ ++ GG +  Q  C  C    + 
Sbjct: 157  KQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDT 216

Query: 1736 EESFTTLNVDIRNHQNLLDSLEQYIKGDLLEGANAYHCEKCDKKVDTVKRLLIKKLPRVL 1795
             + +  + +DI+  Q++  +LEQ +K + L G NAYHC  C ++    K L +    +VL
Sbjct: 217  FDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVL 276

Query: 1796 AIQLKRFDYDWERECAIKFNDYFEFPRELDMGPYTVAGVANLERDNVNSENELIEQKEQS 1855
             + LKRF          K     ++P  LDM PY                          
Sbjct: 277  ILVLKRF----SDVTGNKIAKNVQYPECLDMQPY-------------------------M 307

Query: 1856 DNETAGGTKYRLVGVLVHSG-QASGGHYYSYIIQRNGKDDQTDHWYKFDDGDVT 1908
              +  G   Y L  VLVH+G     GHY+SY+  + G+      WYK DD +VT
Sbjct: 308  SQQNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQ------WYKMDDAEVT 355



 Score = 37.4 bits (85), Expect = 0.19
 Identities = 23/73 (31%), Positives = 32/73 (43%)

Query: 1519 KQIVDCLTEMYYMGTAITTCEALTEWEYLPPVGPRPPKGFVGLKNAGATCYMNSVIQQLY 1578
            K  + C T +            L   E LP    RP     GL+N G TCY+N+ +Q L 
Sbjct: 40   KSPLSCETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYVNASLQCLT 99

Query: 1579 MIPSIRNSILAIE 1591
              P + N +L+ E
Sbjct: 100  YTPPLANYMLSRE 112


>gi|169172882 PREDICTED: Ubiquitin carboxyl-terminal hydrolase 17-like
            protein 3 [Homo sapiens]
          Length = 530

 Score = 87.4 bits (215), Expect = 2e-16
 Identities = 65/238 (27%), Positives = 102/238 (42%), Gaps = 44/238 (18%)

Query: 1684 EQHDALEFFNSLVDSLDEAL----KALGHPA----ILSKVLGGSFADQKICQGCPHRYEC 1735
            +Q D  EF    VD++ +A     K + H +    ++ ++ GG +  Q  C  C    + 
Sbjct: 157  KQEDVHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGCWRSQIKCLHCHGISDT 216

Query: 1736 EESFTTLNVDIRNHQNLLDSLEQYIKGDLLEGANAYHCEKCDKKVDTVKRLLIKKLPRVL 1795
             + +  + +DI+  Q++  +LEQ +K + L G NAYHC  C ++      L +    +VL
Sbjct: 217  FDPYLDIALDIQAAQSVKQALEQLVKPEELNGENAYHCGLCLQRAPASNTLTLHTSAKVL 276

Query: 1796 AIQLKRFDYDWERECAIKFNDYFEFPRELDMGPYTVAGVANLERDNVNSENELIEQKEQS 1855
             + LKRF          K     ++P  LDM PY                          
Sbjct: 277  ILVLKRF----SDVAGNKLAKNVQYPECLDMQPY-------------------------M 307

Query: 1856 DNETAGGTKYRLVGVLVHSG-QASGGHYYSYIIQRNGKDDQTDHWYKFDDGDVTECKM 1912
              +  G   Y L  VLVH+G     GHY+SY+  + G+      WYK DD +VT C +
Sbjct: 308  SQQNTGPLVYVLYAVLVHAGWSCHDGHYFSYVKAQEGQ------WYKMDDAEVTVCSI 359


>gi|239742297 PREDICTED: hypothetical protein XP_002342480 [Homo
            sapiens]
          Length = 530

 Score = 87.4 bits (215), Expect = 2e-16
 Identities = 66/234 (28%), Positives = 102/234 (43%), Gaps = 44/234 (18%)

Query: 1684 EQHDALEFFNSLVDSLDEAL----KALGHPA----ILSKVLGGSFADQKICQGCPHRYEC 1735
            +Q DA EF    VD++ +A     K + H +    ++ ++ GG +  Q  C  C    + 
Sbjct: 157  KQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDT 216

Query: 1736 EESFTTLNVDIRNHQNLLDSLEQYIKGDLLEGANAYHCEKCDKKVDTVKRLLIKKLPRVL 1795
             + +  + +DI+  Q++  +LEQ +K + L G NAYHC  C ++    K L +    +VL
Sbjct: 217  FDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVL 276

Query: 1796 AIQLKRFDYDWERECAIKFNDYFEFPRELDMGPYTVAGVANLERDNVNSENELIEQKEQS 1855
             + LKRF          K     ++P  LDM PY                          
Sbjct: 277  ILVLKRF----SDVTGNKIAKNVQYPECLDMQPY-------------------------M 307

Query: 1856 DNETAGGTKYRLVGVLVHSG-QASGGHYYSYIIQRNGKDDQTDHWYKFDDGDVT 1908
              +  G   Y L  VLVH+G     GHY+SY+  + G+      WYK DD +VT
Sbjct: 308  SQQNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQ------WYKMDDAEVT 355



 Score = 37.4 bits (85), Expect = 0.19
 Identities = 23/73 (31%), Positives = 32/73 (43%)

Query: 1519 KQIVDCLTEMYYMGTAITTCEALTEWEYLPPVGPRPPKGFVGLKNAGATCYMNSVIQQLY 1578
            K  + C T +            L   E LP    RP     GL+N G TCY+N+ +Q L 
Sbjct: 40   KSPLSCETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYVNASLQCLT 99

Query: 1579 MIPSIRNSILAIE 1591
              P + N +L+ E
Sbjct: 100  YTPPLANYMLSRE 112


>gi|239742287 PREDICTED: hypothetical protein XP_002342475 [Homo
            sapiens]
          Length = 530

 Score = 87.4 bits (215), Expect = 2e-16
 Identities = 66/234 (28%), Positives = 102/234 (43%), Gaps = 44/234 (18%)

Query: 1684 EQHDALEFFNSLVDSLDEAL----KALGHPA----ILSKVLGGSFADQKICQGCPHRYEC 1735
            +Q DA EF    VD++ +A     K + H +    ++ ++ GG +  Q  C  C    + 
Sbjct: 157  KQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDT 216

Query: 1736 EESFTTLNVDIRNHQNLLDSLEQYIKGDLLEGANAYHCEKCDKKVDTVKRLLIKKLPRVL 1795
             + +  + +DI+  Q++  +LEQ +K + L G NAYHC  C ++    K L +    +VL
Sbjct: 217  FDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVL 276

Query: 1796 AIQLKRFDYDWERECAIKFNDYFEFPRELDMGPYTVAGVANLERDNVNSENELIEQKEQS 1855
             + LKRF          K     ++P  LDM PY                          
Sbjct: 277  ILVLKRF----SDVTGNKIAKNVQYPECLDMQPY-------------------------M 307

Query: 1856 DNETAGGTKYRLVGVLVHSG-QASGGHYYSYIIQRNGKDDQTDHWYKFDDGDVT 1908
              +  G   Y L  VLVH+G     GHY+SY+  + G+      WYK DD +VT
Sbjct: 308  SQQNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQ------WYKMDDAEVT 355



 Score = 37.4 bits (85), Expect = 0.19
 Identities = 23/73 (31%), Positives = 32/73 (43%)

Query: 1519 KQIVDCLTEMYYMGTAITTCEALTEWEYLPPVGPRPPKGFVGLKNAGATCYMNSVIQQLY 1578
            K  + C T +            L   E LP    RP     GL+N G TCY+N+ +Q L 
Sbjct: 40   KSPLSCETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYVNASLQCLT 99

Query: 1579 MIPSIRNSILAIE 1591
              P + N +L+ E
Sbjct: 100  YTPPLANYMLSRE 112


>gi|32698815 ubiquitin thiolesterase 12 [Homo sapiens]
          Length = 370

 Score = 87.4 bits (215), Expect = 2e-16
 Identities = 99/427 (23%), Positives = 155/427 (36%), Gaps = 119/427 (27%)

Query: 1558 FVGLKNAGATCYMNSVIQQLYMIPSIRNSILAIEGTGSDLHDDMFGDEKQDSESNVDPRD 1617
            + GL N G TCY NSV+Q LY     R  +LA                            
Sbjct: 38   YFGLVNFGNTCYCNSVLQALYFCRPFREKVLAY--------------------------- 70

Query: 1618 DVFGYPHQFEDKPALSKTEDRKEYNIGVLRHLQVIFGHLAASQLQYYV--PRGFWKQFRL 1675
                            K++ RK+ ++  L  L  +F  +A  + +  V  P+ F  + R 
Sbjct: 71   ----------------KSQPRKKESL--LTCLADLFHSIATQKKKVGVIPPKKFITRLRK 112

Query: 1676 WGEPVNLREQHDALEFFNSLVDSLDEALK-----------------------ALGHPAIL 1712
              E  +   Q DA EF N L++++ + L+                       +   P  +
Sbjct: 113  ENELFDNYMQQDAHEFLNYLLNTIADILQEERKQEKQNGRLPNGNIDNENNNSTPDPTWV 172

Query: 1713 SKVLGGSFADQKICQGCPHRYECEESFTTLNVDIRNHQNLLDSLEQYIKGDLLEGANAYH 1772
             ++  G+  ++  C  C      +E F  L+VD+  + ++   L  +   + L     Y+
Sbjct: 173  DEIFQGTLTNETRCLTCETISSKDEDFLDLSVDVEQNTSITHCLRGFSNTETLCSEYKYY 232

Query: 1773 CEKCDKKVDTVKRLLIKKLPRVLAIQLKRFDYDWERECAIKFNDYFEFPRELDMGPYTVA 1832
            CE+C  K +  KR+ +KKLP +LA+ LKRF Y  +     K +    FP EL +      
Sbjct: 233  CEECRSKQEAHKRMKVKKLPMILALHLKRFKYMDQLHRYTKLSYRVVFPLELRL------ 286

Query: 1833 GVANLERDNVNSENELIEQKEQSDNETAGGTKYRLVGVLVHSGQASGGHYYSYIIQRNGK 1892
               N   D  N +                   Y LV V+VH G      +Y  I++ +  
Sbjct: 287  --FNTSGDATNPDR-----------------MYDLVAVVVHCGSGPNRGHYIAIVKSH-- 325

Query: 1893 DDQTDHWYKFDDGDVTECKMDDDEEMKNQCFGGEYMGEVFDHMMKRMSYRRQKRWWNAYI 1952
                D W  FDD  V +      E         E+ G   D           K   + YI
Sbjct: 326  ----DFWLLFDDDIVEKIDAQAIE---------EFYGLTSD---------ISKNSESGYI 363

Query: 1953 LFYEQMD 1959
            LFY+  D
Sbjct: 364  LFYQSRD 370


>gi|157785653 ubiquitin specific peptidase 17 [Homo sapiens]
          Length = 530

 Score = 87.4 bits (215), Expect = 2e-16
 Identities = 66/234 (28%), Positives = 102/234 (43%), Gaps = 44/234 (18%)

Query: 1684 EQHDALEFFNSLVDSLDEAL----KALGHPA----ILSKVLGGSFADQKICQGCPHRYEC 1735
            +Q DA EF    VD++ +A     K + H +    ++ ++ GG +  Q  C  C    + 
Sbjct: 157  KQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDT 216

Query: 1736 EESFTTLNVDIRNHQNLLDSLEQYIKGDLLEGANAYHCEKCDKKVDTVKRLLIKKLPRVL 1795
             + +  + +DI+  Q++  +LEQ +K + L G NAYHC  C ++    K L +    +VL
Sbjct: 217  FDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVL 276

Query: 1796 AIQLKRFDYDWERECAIKFNDYFEFPRELDMGPYTVAGVANLERDNVNSENELIEQKEQS 1855
             + LKRF          K     ++P  LDM PY                          
Sbjct: 277  ILVLKRF----SDVTGNKIAKNVQYPECLDMQPY-------------------------M 307

Query: 1856 DNETAGGTKYRLVGVLVHSG-QASGGHYYSYIIQRNGKDDQTDHWYKFDDGDVT 1908
              +  G   Y L  VLVH+G     GHY+SY+  + G+      WYK DD +VT
Sbjct: 308  SQQNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQ------WYKMDDAEVT 355



 Score = 36.6 bits (83), Expect = 0.33
 Identities = 22/73 (30%), Positives = 32/73 (43%)

Query: 1519 KQIVDCLTEMYYMGTAITTCEALTEWEYLPPVGPRPPKGFVGLKNAGATCYMNSVIQQLY 1578
            K  + C T +            L   E LP    RP     GL+N G TCY+N+ ++ L 
Sbjct: 40   KSPLSCETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYVNASLEWLT 99

Query: 1579 MIPSIRNSILAIE 1591
              P + N +L+ E
Sbjct: 100  YTPPLANYMLSRE 112


>gi|169217654 PREDICTED: similar to deubiquitinating enzyme DUB1 [Homo
            sapiens]
          Length = 530

 Score = 86.7 bits (213), Expect = 3e-16
 Identities = 66/234 (28%), Positives = 101/234 (43%), Gaps = 44/234 (18%)

Query: 1684 EQHDALEFFNSLVDSLDEAL----KALGHPA----ILSKVLGGSFADQKICQGCPHRYEC 1735
            +Q DA EF    VD++ +A     K   H +    ++ ++ GG +  Q  C  C    + 
Sbjct: 157  KQEDAHEFLMFTVDAMKKACLPGHKQADHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDT 216

Query: 1736 EESFTTLNVDIRNHQNLLDSLEQYIKGDLLEGANAYHCEKCDKKVDTVKRLLIKKLPRVL 1795
             + +  + +DI+  Q++  +LEQ +K + L G NAYHC  C ++    K L +    +VL
Sbjct: 217  FDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVL 276

Query: 1796 AIQLKRFDYDWERECAIKFNDYFEFPRELDMGPYTVAGVANLERDNVNSENELIEQKEQS 1855
             + LKRF          K     ++P  LDM PY                          
Sbjct: 277  ILVLKRF----SDVTGNKIAKNVQYPECLDMQPY-------------------------M 307

Query: 1856 DNETAGGTKYRLVGVLVHSG-QASGGHYYSYIIQRNGKDDQTDHWYKFDDGDVT 1908
              +  G   Y L  VLVH+G     GHY+SY+  + G+      WYK DD +VT
Sbjct: 308  SQQNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQ------WYKMDDAEVT 355



 Score = 37.4 bits (85), Expect = 0.19
 Identities = 23/73 (31%), Positives = 32/73 (43%)

Query: 1519 KQIVDCLTEMYYMGTAITTCEALTEWEYLPPVGPRPPKGFVGLKNAGATCYMNSVIQQLY 1578
            K  + C T +            L   E LP    RP     GL+N G TCY+N+ +Q L 
Sbjct: 40   KSPLSCETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYVNASLQCLT 99

Query: 1579 MIPSIRNSILAIE 1591
              P + N +L+ E
Sbjct: 100  YTPPLANYMLSRE 112


>gi|113415490 PREDICTED: similar to deubiquitinating enzyme 1 [Homo
            sapiens]
          Length = 530

 Score = 86.3 bits (212), Expect = 4e-16
 Identities = 66/234 (28%), Positives = 101/234 (43%), Gaps = 44/234 (18%)

Query: 1684 EQHDALEFFNSLVDSLDEAL----KALGHPA----ILSKVLGGSFADQKICQGCPHRYEC 1735
            +Q DA EF    VD++ +A     K + H +    ++ ++ GG +  Q  C  C    + 
Sbjct: 157  KQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDT 216

Query: 1736 EESFTTLNVDIRNHQNLLDSLEQYIKGDLLEGANAYHCEKCDKKVDTVKRLLIKKLPRVL 1795
             + +  + +DI+  Q++  +LEQ +K + L G NAYHC  C ++    K L +    +VL
Sbjct: 217  FDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVL 276

Query: 1796 AIQLKRFDYDWERECAIKFNDYFEFPRELDMGPYTVAGVANLERDNVNSENELIEQKEQS 1855
             + LKRF          K     ++P  LDM PY                          
Sbjct: 277  ILVLKRF----SDVTGNKIAKNVQYPECLDMQPY-------------------------M 307

Query: 1856 DNETAGGTKYRLVGVLVHSG-QASGGHYYSYIIQRNGKDDQTDHWYKFDDGDVT 1908
                 G   Y L  VLVH+G     GHY+SY+  + G+      WYK DD +VT
Sbjct: 308  SQPNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQ------WYKMDDAEVT 355



 Score = 37.4 bits (85), Expect = 0.19
 Identities = 23/73 (31%), Positives = 32/73 (43%)

Query: 1519 KQIVDCLTEMYYMGTAITTCEALTEWEYLPPVGPRPPKGFVGLKNAGATCYMNSVIQQLY 1578
            K  + C T +            L   E LP    RP     GL+N G TCY+N+ +Q L 
Sbjct: 40   KSPLSCETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYVNASLQCLT 99

Query: 1579 MIPSIRNSILAIE 1591
              P + N +L+ E
Sbjct: 100  YTPPLANYMLSRE 112


>gi|113415488 PREDICTED: similar to deubiquitinating enzyme 1 [Homo
            sapiens]
          Length = 530

 Score = 86.3 bits (212), Expect = 4e-16
 Identities = 66/234 (28%), Positives = 101/234 (43%), Gaps = 44/234 (18%)

Query: 1684 EQHDALEFFNSLVDSLDEAL----KALGHPA----ILSKVLGGSFADQKICQGCPHRYEC 1735
            +Q DA EF    VD++ +A     K + H +    ++ ++ GG +  Q  C  C    + 
Sbjct: 157  KQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDT 216

Query: 1736 EESFTTLNVDIRNHQNLLDSLEQYIKGDLLEGANAYHCEKCDKKVDTVKRLLIKKLPRVL 1795
             + +  + +DI+  Q++  +LEQ +K + L G NAYHC  C ++    K L +    +VL
Sbjct: 217  FDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVL 276

Query: 1796 AIQLKRFDYDWERECAIKFNDYFEFPRELDMGPYTVAGVANLERDNVNSENELIEQKEQS 1855
             + LKRF          K     ++P  LDM PY                          
Sbjct: 277  ILVLKRF----SDVTGNKIAKNVQYPECLDMQPY-------------------------M 307

Query: 1856 DNETAGGTKYRLVGVLVHSG-QASGGHYYSYIIQRNGKDDQTDHWYKFDDGDVT 1908
                 G   Y L  VLVH+G     GHY+SY+  + G+      WYK DD +VT
Sbjct: 308  SQPNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQ------WYKMDDAEVT 355



 Score = 37.4 bits (85), Expect = 0.19
 Identities = 23/73 (31%), Positives = 32/73 (43%)

Query: 1519 KQIVDCLTEMYYMGTAITTCEALTEWEYLPPVGPRPPKGFVGLKNAGATCYMNSVIQQLY 1578
            K  + C T +            L   E LP    RP     GL+N G TCY+N+ +Q L 
Sbjct: 40   KSPLSCETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYVNASLQCLT 99

Query: 1579 MIPSIRNSILAIE 1591
              P + N +L+ E
Sbjct: 100  YTPPLANYMLSRE 112


>gi|113415486 PREDICTED: similar to deubiquitinating enzyme 1 [Homo
            sapiens]
          Length = 530

 Score = 86.3 bits (212), Expect = 4e-16
 Identities = 66/234 (28%), Positives = 101/234 (43%), Gaps = 44/234 (18%)

Query: 1684 EQHDALEFFNSLVDSLDEAL----KALGHPA----ILSKVLGGSFADQKICQGCPHRYEC 1735
            +Q DA EF    VD++ +A     K + H +    ++ ++ GG +  Q  C  C    + 
Sbjct: 157  KQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDT 216

Query: 1736 EESFTTLNVDIRNHQNLLDSLEQYIKGDLLEGANAYHCEKCDKKVDTVKRLLIKKLPRVL 1795
             + +  + +DI+  Q++  +LEQ +K + L G NAYHC  C ++    K L +    +VL
Sbjct: 217  FDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVL 276

Query: 1796 AIQLKRFDYDWERECAIKFNDYFEFPRELDMGPYTVAGVANLERDNVNSENELIEQKEQS 1855
             + LKRF          K     ++P  LDM PY                          
Sbjct: 277  ILVLKRF----SDVTGNKIAKNVQYPECLDMQPY-------------------------M 307

Query: 1856 DNETAGGTKYRLVGVLVHSG-QASGGHYYSYIIQRNGKDDQTDHWYKFDDGDVT 1908
                 G   Y L  VLVH+G     GHY+SY+  + G+      WYK DD +VT
Sbjct: 308  SQPNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQ------WYKMDDAEVT 355



 Score = 37.4 bits (85), Expect = 0.19
 Identities = 23/73 (31%), Positives = 32/73 (43%)

Query: 1519 KQIVDCLTEMYYMGTAITTCEALTEWEYLPPVGPRPPKGFVGLKNAGATCYMNSVIQQLY 1578
            K  + C T +            L   E LP    RP     GL+N G TCY+N+ +Q L 
Sbjct: 40   KSPLSCETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYVNASLQCLT 99

Query: 1579 MIPSIRNSILAIE 1591
              P + N +L+ E
Sbjct: 100  YTPPLANYMLSRE 112


>gi|113415484 PREDICTED: similar to deubiquitinating enzyme 1 [Homo
            sapiens]
          Length = 530

 Score = 86.3 bits (212), Expect = 4e-16
 Identities = 66/234 (28%), Positives = 101/234 (43%), Gaps = 44/234 (18%)

Query: 1684 EQHDALEFFNSLVDSLDEAL----KALGHPA----ILSKVLGGSFADQKICQGCPHRYEC 1735
            +Q DA EF    VD++ +A     K + H +    ++ ++ GG +  Q  C  C    + 
Sbjct: 157  KQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDT 216

Query: 1736 EESFTTLNVDIRNHQNLLDSLEQYIKGDLLEGANAYHCEKCDKKVDTVKRLLIKKLPRVL 1795
             + +  + +DI+  Q++  +LEQ +K + L G NAYHC  C ++    K L +    +VL
Sbjct: 217  FDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVL 276

Query: 1796 AIQLKRFDYDWERECAIKFNDYFEFPRELDMGPYTVAGVANLERDNVNSENELIEQKEQS 1855
             + LKRF          K     ++P  LDM PY                          
Sbjct: 277  ILVLKRF----SDVTGNKIAKNVQYPECLDMQPY-------------------------M 307

Query: 1856 DNETAGGTKYRLVGVLVHSG-QASGGHYYSYIIQRNGKDDQTDHWYKFDDGDVT 1908
                 G   Y L  VLVH+G     GHY+SY+  + G+      WYK DD +VT
Sbjct: 308  SQPNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQ------WYKMDDAEVT 355



 Score = 37.4 bits (85), Expect = 0.19
 Identities = 23/73 (31%), Positives = 32/73 (43%)

Query: 1519 KQIVDCLTEMYYMGTAITTCEALTEWEYLPPVGPRPPKGFVGLKNAGATCYMNSVIQQLY 1578
            K  + C T +            L   E LP    RP     GL+N G TCY+N+ +Q L 
Sbjct: 40   KSPLSCETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYVNASLQCLT 99

Query: 1579 MIPSIRNSILAIE 1591
              P + N +L+ E
Sbjct: 100  YTPPLANYMLSRE 112


>gi|113415480 PREDICTED: similar to deubiquitinating enzyme 1 [Homo
            sapiens]
          Length = 530

 Score = 86.3 bits (212), Expect = 4e-16
 Identities = 66/234 (28%), Positives = 101/234 (43%), Gaps = 44/234 (18%)

Query: 1684 EQHDALEFFNSLVDSLDEAL----KALGHPA----ILSKVLGGSFADQKICQGCPHRYEC 1735
            +Q DA EF    VD++ +A     K + H +    ++ ++ GG +  Q  C  C    + 
Sbjct: 157  KQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDT 216

Query: 1736 EESFTTLNVDIRNHQNLLDSLEQYIKGDLLEGANAYHCEKCDKKVDTVKRLLIKKLPRVL 1795
             + +  + +DI+  Q++  +LEQ +K + L G NAYHC  C ++    K L +    +VL
Sbjct: 217  FDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVL 276

Query: 1796 AIQLKRFDYDWERECAIKFNDYFEFPRELDMGPYTVAGVANLERDNVNSENELIEQKEQS 1855
             + LKRF          K     ++P  LDM PY                          
Sbjct: 277  ILVLKRF----SDVTGNKIAKNVQYPECLDMQPY-------------------------M 307

Query: 1856 DNETAGGTKYRLVGVLVHSG-QASGGHYYSYIIQRNGKDDQTDHWYKFDDGDVT 1908
                 G   Y L  VLVH+G     GHY+SY+  + G+      WYK DD +VT
Sbjct: 308  SQPNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQ------WYKMDDAEVT 355



 Score = 37.4 bits (85), Expect = 0.19
 Identities = 23/73 (31%), Positives = 32/73 (43%)

Query: 1519 KQIVDCLTEMYYMGTAITTCEALTEWEYLPPVGPRPPKGFVGLKNAGATCYMNSVIQQLY 1578
            K  + C T +            L   E LP    RP     GL+N G TCY+N+ +Q L 
Sbjct: 40   KSPLSCETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYVNASLQCLT 99

Query: 1579 MIPSIRNSILAIE 1591
              P + N +L+ E
Sbjct: 100  YTPPLANYMLSRE 112


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.136    0.412 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 100,452,753
Number of Sequences: 37866
Number of extensions: 4660983
Number of successful extensions: 15435
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 98
Number of HSP's successfully gapped in prelim test: 21
Number of HSP's that attempted gapping in prelim test: 14873
Number of HSP's gapped (non-prelim): 358
length of query: 2555
length of database: 18,247,518
effective HSP length: 119
effective length of query: 2436
effective length of database: 13,741,464
effective search space: 33474206304
effective search space used: 33474206304
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 71 (32.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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