Search of human proteins with 74275344

Search of human proteins with 74275344

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|74275344 trace amine associated receptor 2 isoform 1 [Homo
sapiens]
         (351 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|74275344 trace amine associated receptor 2 isoform 1 [Homo sa...   726   0.0  
gi|74275342 trace amine associated receptor 2 isoform 2 [Homo sa...   635   0.0  
gi|21264324 trace amine associated receptor 1 [Homo sapiens]          327   1e-89
gi|223633986 trace amine associated receptor 5 [Homo sapiens]         285   3e-77
gi|28173558 trace amine associated receptor 6 [Homo sapiens]          264   8e-71
gi|110618256 trace amine associated receptor 9 [Homo sapiens]         264   1e-70
gi|16751917 trace amine associated receptor 8 [Homo sapiens]          250   1e-66
gi|94421462 serotonin 5-HT4 receptor isoform n [Homo sapiens]         192   3e-49
gi|94421460 serotonin 5-HT4 receptor isoform i [Homo sapiens]         192   3e-49
gi|94421456 serotonin 5-HT4 receptor isoform d [Homo sapiens]         192   3e-49
gi|94421454 serotonin 5-HT4 receptor isoform a [Homo sapiens]         192   3e-49
gi|41282074 serotonin 5-HT4 receptor isoform g [Homo sapiens]         192   3e-49
gi|11321563 serotonin 5-HT4 receptor isoform b [Homo sapiens]         192   3e-49
gi|94421458 serotonin 5-HT4 receptor isoform hb [Homo sapiens]        191   8e-49
gi|111118990 alpha-1A-adrenergic receptor isoform 4 [Homo sapiens]    148   6e-36
gi|111118992 alpha-1A-adrenergic receptor isoform 1 [Homo sapiens]    148   6e-36
gi|111118986 alpha-1A-adrenergic receptor isoform 2 [Homo sapiens]    148   6e-36
gi|111118988 alpha-1A-adrenergic receptor isoform 3 [Homo sapiens]    148   6e-36
gi|197085610 histamine receptor H2 isoform 1 [Homo sapiens]           145   4e-35
gi|13435405 histamine receptor H2 isoform 2 [Homo sapiens]            145   4e-35
gi|4501959 alpha-1B-adrenergic receptor [Homo sapiens]                145   7e-35
gi|4503383 dopamine receptor D1 [Homo sapiens]                        142   3e-34
gi|4504535 5-hydroxytryptamine (serotonin) receptor 1D [Homo sap...   141   1e-33
gi|4501969 adrenergic, beta-2-, receptor, surface [Homo sapiens]      139   5e-33
gi|10880131 5-hydroxytryptamine receptor 7 isoform b [Homo sapiens]   131   8e-31
gi|10880129 5-hydroxytryptamine receptor 7 isoform d [Homo sapiens]   131   8e-31
gi|4504547 5-hydroxytryptamine receptor 7 isoform a [Homo sapiens]    131   8e-31
gi|4504537 5-hydroxytryptamine (serotonin) receptor 1E [Homo sap...   125   7e-29
gi|4557267 adrenergic, beta-3-, receptor [Homo sapiens]               121   1e-27
gi|16604258 neuropeptide FF receptor 2 isoform 2 [Homo sapiens]       119   5e-27

>gi|74275344 trace amine associated receptor 2 isoform 1 [Homo
           sapiens]
          Length = 351

 Score =  726 bits (1875), Expect = 0.0
 Identities = 351/351 (100%), Positives = 351/351 (100%)

Query: 1   MAVSSEQHELSHFKRTQTKKEKFNCSEYGNRSCPENERSLGVRVAMYSFMAGSIFITIFG 60
           MAVSSEQHELSHFKRTQTKKEKFNCSEYGNRSCPENERSLGVRVAMYSFMAGSIFITIFG
Sbjct: 1   MAVSSEQHELSHFKRTQTKKEKFNCSEYGNRSCPENERSLGVRVAMYSFMAGSIFITIFG 60

Query: 61  NLAMIISISYFKQLHTPTNFLILSMAITDFLLGFTIMPYSMIRSVENCWYFGLTFCKIYY 120
           NLAMIISISYFKQLHTPTNFLILSMAITDFLLGFTIMPYSMIRSVENCWYFGLTFCKIYY
Sbjct: 61  NLAMIISISYFKQLHTPTNFLILSMAITDFLLGFTIMPYSMIRSVENCWYFGLTFCKIYY 120

Query: 121 SFDLMLSITSIFHLCSVAIDRFYAICYPLLYSTKITIPVIKRLLLLCWSVPGAFAFGVVF 180
           SFDLMLSITSIFHLCSVAIDRFYAICYPLLYSTKITIPVIKRLLLLCWSVPGAFAFGVVF
Sbjct: 121 SFDLMLSITSIFHLCSVAIDRFYAICYPLLYSTKITIPVIKRLLLLCWSVPGAFAFGVVF 180

Query: 181 SEAYADGIEGYDILVACSSSCPVMFNKLWGTTLFMAGFFTPGSMMVGIYGKIFAVSRKHA 240
           SEAYADGIEGYDILVACSSSCPVMFNKLWGTTLFMAGFFTPGSMMVGIYGKIFAVSRKHA
Sbjct: 181 SEAYADGIEGYDILVACSSSCPVMFNKLWGTTLFMAGFFTPGSMMVGIYGKIFAVSRKHA 240

Query: 241 HAINNLRENQNNQVKKDKKAAKTLGIVIGVFLLCWFPCFFTILLDPFLNFSTPVVLFDAL 300
           HAINNLRENQNNQVKKDKKAAKTLGIVIGVFLLCWFPCFFTILLDPFLNFSTPVVLFDAL
Sbjct: 241 HAINNLRENQNNQVKKDKKAAKTLGIVIGVFLLCWFPCFFTILLDPFLNFSTPVVLFDAL 300

Query: 301 TWFGYFNSTCNPLIYGFFYPWFRRALKYILLGKIFSSCFHNTILCMQKESE 351
           TWFGYFNSTCNPLIYGFFYPWFRRALKYILLGKIFSSCFHNTILCMQKESE
Sbjct: 301 TWFGYFNSTCNPLIYGFFYPWFRRALKYILLGKIFSSCFHNTILCMQKESE 351


>gi|74275342 trace amine associated receptor 2 isoform 2 [Homo
           sapiens]
          Length = 306

 Score =  635 bits (1638), Expect = 0.0
 Identities = 306/306 (100%), Positives = 306/306 (100%)

Query: 46  MYSFMAGSIFITIFGNLAMIISISYFKQLHTPTNFLILSMAITDFLLGFTIMPYSMIRSV 105
           MYSFMAGSIFITIFGNLAMIISISYFKQLHTPTNFLILSMAITDFLLGFTIMPYSMIRSV
Sbjct: 1   MYSFMAGSIFITIFGNLAMIISISYFKQLHTPTNFLILSMAITDFLLGFTIMPYSMIRSV 60

Query: 106 ENCWYFGLTFCKIYYSFDLMLSITSIFHLCSVAIDRFYAICYPLLYSTKITIPVIKRLLL 165
           ENCWYFGLTFCKIYYSFDLMLSITSIFHLCSVAIDRFYAICYPLLYSTKITIPVIKRLLL
Sbjct: 61  ENCWYFGLTFCKIYYSFDLMLSITSIFHLCSVAIDRFYAICYPLLYSTKITIPVIKRLLL 120

Query: 166 LCWSVPGAFAFGVVFSEAYADGIEGYDILVACSSSCPVMFNKLWGTTLFMAGFFTPGSMM 225
           LCWSVPGAFAFGVVFSEAYADGIEGYDILVACSSSCPVMFNKLWGTTLFMAGFFTPGSMM
Sbjct: 121 LCWSVPGAFAFGVVFSEAYADGIEGYDILVACSSSCPVMFNKLWGTTLFMAGFFTPGSMM 180

Query: 226 VGIYGKIFAVSRKHAHAINNLRENQNNQVKKDKKAAKTLGIVIGVFLLCWFPCFFTILLD 285
           VGIYGKIFAVSRKHAHAINNLRENQNNQVKKDKKAAKTLGIVIGVFLLCWFPCFFTILLD
Sbjct: 181 VGIYGKIFAVSRKHAHAINNLRENQNNQVKKDKKAAKTLGIVIGVFLLCWFPCFFTILLD 240

Query: 286 PFLNFSTPVVLFDALTWFGYFNSTCNPLIYGFFYPWFRRALKYILLGKIFSSCFHNTILC 345
           PFLNFSTPVVLFDALTWFGYFNSTCNPLIYGFFYPWFRRALKYILLGKIFSSCFHNTILC
Sbjct: 241 PFLNFSTPVVLFDALTWFGYFNSTCNPLIYGFFYPWFRRALKYILLGKIFSSCFHNTILC 300

Query: 346 MQKESE 351
           MQKESE
Sbjct: 301 MQKESE 306


>gi|21264324 trace amine associated receptor 1 [Homo sapiens]
          Length = 339

 Score =  327 bits (838), Expect = 1e-89
 Identities = 163/322 (50%), Positives = 213/322 (66%), Gaps = 13/322 (4%)

Query: 25  CSEYGNRSCPENERSLGVRVAMYSFMAGSIFITIFGNLAMIISISYFKQLHTPTNFLILS 84
           C    N SC +N  S  VR ++YS M   I  T+ GNL +I+SIS+FKQLHTPTN+LI S
Sbjct: 5   CHNIINISCVKNNWSNDVRASLYSLMVLIILTTLVGNLIVIVSISHFKQLHTPTNWLIHS 64

Query: 85  MAITDFLLGFTIMPYSMIRSVENCWYFGLTFCKIYYSFDLMLSITSIFHLCSVAIDRFYA 144
           MA  DFLLG  +MPYSM+RS E+CWYFG  FCKI+ S D+MLS  SIFHL  ++IDR+YA
Sbjct: 65  MATVDFLLGCLVMPYSMVRSAEHCWYFGEVFCKIHTSTDIMLSSASIFHLSFISIDRYYA 124

Query: 145 ICYPLLYSTKITIPVIKRLLLLCWSVPGAFAFGVVFSEAYADGIEG-YDILVACSSSCPV 203
           +C PL Y  K+ I VI  ++ + WSVP  FAFG++F E    G E  Y   V C   C V
Sbjct: 125 VCDPLRYKAKMNILVICVMIFISWSVPAVFAFGMIFLELNFKGAEEIYYKHVHCRGGCSV 184

Query: 204 MFNKLWGTTLFMAGFFTPGSMMVGIYGKIFAVSRKHAHAINNLRENQNNQV--------- 254
            F+K+ G   FM  F+ PGS+M+ +Y +I+ ++++ A  I++   NQ  Q+         
Sbjct: 185 FFSKISGVLTFMTSFYIPGSIMLCVYYRIYLIAKEQARLISD--ANQKLQIGLEMKNGIS 242

Query: 255 -KKDKKAAKTLGIVIGVFLLCWFPCFFTILLDPFLNFSTPVVLFDALTWFGYFNSTCNPL 313
             K++KA KTLGIV+GVFL+CW P F   ++DPFL++  P  L D L WFGY NST NP+
Sbjct: 243 QSKERKAVKTLGIVMGVFLICWCPFFICTVMDPFLHYIIPPTLNDVLIWFGYLNSTFNPM 302

Query: 314 IYGFFYPWFRRALKYILLGKIF 335
           +Y FFYPWFR+ALK +L GKIF
Sbjct: 303 VYAFFYPWFRKALKMMLFGKIF 324


>gi|223633986 trace amine associated receptor 5 [Homo sapiens]
          Length = 337

 Score =  285 bits (730), Expect = 3e-77
 Identities = 133/307 (43%), Positives = 191/307 (62%), Gaps = 1/307 (0%)

Query: 30  NRSCPENERSLGVRVAMYSFMAGSIFITIFGNLAMIISISYFKQLHTPTNFLILSMAITD 89
           N SCP    +LG+++ +Y   A  + I + GN+ +  ++SYFK LHTPTNFL+LS+A+ D
Sbjct: 21  NGSCPRTVHTLGIQLVIYLACAAGMLIIVLGNVFVAFAVSYFKALHTPTNFLLLSLALAD 80

Query: 90  FLLGFTIMPYSMIRSVENCWYFGLTFCKIYYSFDLMLSITSIFHLCSVAIDRFYAICYPL 149
             LG  ++P S IRSVE+CW+FG   C+++   D +  +TSIFHLC ++IDR  AIC PL
Sbjct: 81  MFLGLLVLPLSTIRSVESCWFFGDFLCRLHTYLDTLFCLTSIFHLCFISIDRHCAICDPL 140

Query: 150 LYSTKITIPVIKRLLLLCWSVPGAFAFGVVFSEAYADGIEGYDILVACSSSCPVMFNKLW 209
           LY +K T+ V  R +L  W VP A+    ++++     +  +   + C  SC ++ NK W
Sbjct: 141 LYPSKFTVRVALRYILAGWGVPAAYTSLFLYTDVVETRLSQWLEEMPCVGSCQLLLNKFW 200

Query: 210 GTTLFMAGFFTPGSMMVGIYGKIFAVSRKHAHAINNLRENQNNQVKKDKKAAKTLGIVIG 269
           G   F   FF P  +M+ +Y KIF V+ + A  I  L ++     K ++KAAKTLGI +G
Sbjct: 201 GWLNFPL-FFVPCLIMISLYVKIFVVATRQAQQITTLSKSLAGAAKHERKAAKTLGIAVG 259

Query: 270 VFLLCWFPCFFTILLDPFLNFSTPVVLFDALTWFGYFNSTCNPLIYGFFYPWFRRALKYI 329
           ++LLCW P     ++D  L+F TP ++FD   WF YFNS CNP+IY F Y WFR+ALK  
Sbjct: 260 IYLLCWLPFTIDTMVDSLLHFITPPLVFDIFIWFAYFNSACNPIIYVFSYQWFRKALKLT 319

Query: 330 LLGKIFS 336
           L  K+FS
Sbjct: 320 LSQKVFS 326


>gi|28173558 trace amine associated receptor 6 [Homo sapiens]
          Length = 345

 Score =  264 bits (675), Expect = 8e-71
 Identities = 125/321 (38%), Positives = 191/321 (59%), Gaps = 9/321 (2%)

Query: 25  CSEYGNRSCPENERSLGVRVAMYSFMAGSIFITIFGNLAMIISISYFKQLHTPTNFLILS 84
           C    N SC +   S G RV +Y        + +FGNL ++ISI +FKQLH+PTNFL+ S
Sbjct: 14  CYANVNGSCVKIPFSPGSRVILYIVFGFGAVLAVFGNLLVMISILHFKQLHSPTNFLVAS 73

Query: 85  MAITDFLLGFTIMPYSMIRSVENCWYFGLTFCKIYYSFDLMLSITSIFHLCSVAIDRFYA 144
           +A  DFL+G T+MP+SM+R+VE+CWYFG +FC  +   D+    +S+FHLC ++IDR+ A
Sbjct: 74  LACADFLVGVTVMPFSMVRTVESCWYFGRSFCTFHTCCDVAFCYSSLFHLCFISIDRYIA 133

Query: 145 ICYPLLYSTKITIPVIKRLLLLCWSVPGAFAFGVVFSEAYADGIEGYDILVACSSSCPVM 204
           +  PL+Y TK T+ V    + + W +P  ++  V ++  Y DG+E     + C   C  +
Sbjct: 134 VTDPLVYPTKFTVSVSGICISVSWILPLMYSGAVFYTGVYDDGLEELSDALNCIGGCQTV 193

Query: 205 FNKLWGTTLFMAGFFTPGSMMVGIYGKIFAVSRKHAHAINNLRENQNNQ--------VKK 256
            N+ W  T F++ FF P  +M+ +YG IF V+R+ A  I N      +          ++
Sbjct: 194 VNQNWVLTDFLS-FFIPTFIMIILYGNIFLVARRQAKKIENTGSKTESSSESYKARVARR 252

Query: 257 DKKAAKTLGIVIGVFLLCWFPCFFTILLDPFLNFSTPVVLFDALTWFGYFNSTCNPLIYG 316
           ++KAAKTLG+ +  F++ W P     L+D F+ F TP  +++   W  Y+NS  NPLIY 
Sbjct: 253 ERKAAKTLGVTVVAFMISWLPYSIDSLIDAFMGFITPACIYEICCWCAYYNSAMNPLIYA 312

Query: 317 FFYPWFRRALKYILLGKIFSS 337
            FYPWFR+A+K I+ G++  +
Sbjct: 313 LFYPWFRKAIKVIVTGQVLKN 333


>gi|110618256 trace amine associated receptor 9 [Homo sapiens]
          Length = 348

 Score =  264 bits (674), Expect = 1e-70
 Identities = 127/318 (39%), Positives = 186/318 (58%), Gaps = 9/318 (2%)

Query: 25  CSEYGNRSCPENERSLGVRVAMYSFMAGSIFITIFGNLAMIISISYFKQLHTPTNFLILS 84
           C +  N SC +   S G R  +Y+ +     +  FGNL ++I+I +FKQLHTPTNFLI S
Sbjct: 14  CYKNVNESCIKTPYSPGPRSILYAVLGFGAVLAAFGNLLVMIAILHFKQLHTPTNFLIAS 73

Query: 85  MAITDFLLGFTIMPYSMIRSVENCWYFGLTFCKIYYSFDLMLSITSIFHLCSVAIDRFYA 144
           +A  DFL+G T+MP+S +RSVE+CWYFG ++CK +  FD      S+FHLC +++DR+ A
Sbjct: 74  LACADFLVGVTVMPFSTVRSVESCWYFGDSYCKFHTCFDTSFCFASLFHLCCISVDRYIA 133

Query: 145 ICYPLLYSTKITIPVIKRLLLLCWSVPGAFAFGVVFSEAYADGIEGYDILVACSSSCPVM 204
           +  PL Y TK T+ V    ++L W     ++F + ++ A  +GIE   + + C   C   
Sbjct: 134 VTDPLTYPTKFTVSVSGICIVLSWFFSVTYSFSIFYTGANEEGIEELVVALTCVGGCQAP 193

Query: 205 FNKLWGTTLFMAGFFTPGSMMVGIYGKIFAVSRKHAHAINNLRENQNNQ--------VKK 256
            N+ W    F+  FF P   MV IY KIF V++  A  I +      +          K+
Sbjct: 194 LNQNWVLLCFLL-FFIPNVAMVFIYSKIFLVAKHQARKIESTASQAQSSSESYKERVAKR 252

Query: 257 DKKAAKTLGIVIGVFLLCWFPCFFTILLDPFLNFSTPVVLFDALTWFGYFNSTCNPLIYG 316
           ++KAAKTLGI +  FL+ W P     ++D ++NF TP  +++ L W  Y+NS  NPLIY 
Sbjct: 253 ERKAAKTLGIAMAAFLVSWLPYLVDAVIDAYMNFITPPYVYEILVWCVYYNSAMNPLIYA 312

Query: 317 FFYPWFRRALKYILLGKI 334
           FFY WF +A+K I+ GK+
Sbjct: 313 FFYQWFGKAIKLIVSGKV 330


>gi|16751917 trace amine associated receptor 8 [Homo sapiens]
          Length = 342

 Score =  250 bits (639), Expect = 1e-66
 Identities = 120/321 (37%), Positives = 187/321 (58%), Gaps = 9/321 (2%)

Query: 25  CSEYGNRSCPENERSLGVRVAMYSFMAGSIFITIFGNLAMIISISYFKQLHTPTNFLILS 84
           C E  N SC E   S G RV +Y+  +    + +FGNL ++ S+ +FKQLH+PTNFLI S
Sbjct: 13  CYEDVNGSCIETPYSPGSRVILYTAFSFGSLLAVFGNLLVMTSVLHFKQLHSPTNFLIAS 72

Query: 85  MAITDFLLGFTIMPYSMIRSVENCWYFGLTFCKIYYSFDLMLSITSIFHLCSVAIDRFYA 144
           +A  DFL+G T+M +SM+R+VE+CWYFG  FC ++   D+    +S+ HLC + IDR+  
Sbjct: 73  LACADFLVGVTVMLFSMVRTVESCWYFGAKFCTLHSCCDVAFCYSSVLHLCFICIDRYIV 132

Query: 145 ICYPLLYSTKITIPVIKRLLLLCWSVPGAFAFGVVFSEAYADGIEGYDILVACSSSCPVM 204
           +  PL+Y+TK T+ V    + + W +P  ++  V ++    DG+E     + C   C ++
Sbjct: 133 VTDPLVYATKFTVSVSGICISVSWILPLTYSGAVFYTGVNDDGLEELVSALNCVGGCQII 192

Query: 205 FNKLWGTTLFMAGFFTPGSMMVGIYGKIFAVSRKHAHAINNLRENQNNQ--------VKK 256
            ++ W    F+  FF P  +M+ +Y KIF ++++ A  I        +          K+
Sbjct: 193 VSQGWVLIDFLL-FFIPTLVMIILYSKIFLIAKQQAIKIETTSSKVESSSESYKIRVAKR 251

Query: 257 DKKAAKTLGIVIGVFLLCWFPCFFTILLDPFLNFSTPVVLFDALTWFGYFNSTCNPLIYG 316
           ++KAAKTLG+ +  F++ W P    IL+D F+ F TP  +++   W  Y+NS  NPLIY 
Sbjct: 252 ERKAAKTLGVTVLAFVISWLPYTVDILIDAFMGFLTPAYIYEICCWSAYYNSAMNPLIYA 311

Query: 317 FFYPWFRRALKYILLGKIFSS 337
            FYPWFR+A+K IL G +  +
Sbjct: 312 LFYPWFRKAIKLILSGDVLKA 332


>gi|94421462 serotonin 5-HT4 receptor isoform n [Homo sapiens]
          Length = 359

 Score =  192 bits (489), Expect = 3e-49
 Identities = 105/311 (33%), Positives = 173/311 (55%), Gaps = 25/311 (8%)

Query: 43  RVAMYSFMAGSIFITIFGNLAMIISISYFKQLHT-PTNFLILSMAITDFLLGFTIMPYSM 101
           +V + +F++  I + I GNL +++++ + +QL    TN+ I+S+A  D L+   +MP+  
Sbjct: 19  KVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGA 78

Query: 102 IRSVENCWYFGLTFCKIYYSFDLMLSITSIFHLCSVAIDRFYAIC-YPLLYSTKITIPVI 160
           I  V++ W +G  FC +  S D++L+  SIFHLC +++DR+YAIC  PL+Y  K+T   I
Sbjct: 79  IELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRI 138

Query: 161 KRLLLLCWSVPGAFAFGVVFSEAYADGIEGYDILV-------ACSSSCPVMFNKLWGTTL 213
             +L  CW +P   +F  +       GI   D++        + S+ C  M NK +  T 
Sbjct: 139 ALMLGGCWVIPTFISFLPIMQGWNNIGI--IDLIEKRKFNQNSNSTYCVFMVNKPYAITC 196

Query: 214 FMAGFFTPGSMMVGIYGKIFAVSRKHAHAINNLR--------------ENQNNQVKKDKK 259
            +  F+ P  +MV  Y +I+  +++HAH I  L+              ++  ++++ + K
Sbjct: 197 SVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHRMRTETK 256

Query: 260 AAKTLGIVIGVFLLCWFPCFFTILLDPFLNFSTPVVLFDALTWFGYFNSTCNPLIYGFFY 319
           AAKTL I++G F LCW P F T ++DPF++++ P  ++ A  W GY NS  NP +Y F  
Sbjct: 257 AAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWLGYINSGLNPFLYAFLN 316

Query: 320 PWFRRALKYIL 330
             FRRA   IL
Sbjct: 317 KSFRRAFLIIL 327


>gi|94421460 serotonin 5-HT4 receptor isoform i [Homo sapiens]
          Length = 428

 Score =  192 bits (489), Expect = 3e-49
 Identities = 105/311 (33%), Positives = 173/311 (55%), Gaps = 25/311 (8%)

Query: 43  RVAMYSFMAGSIFITIFGNLAMIISISYFKQLHT-PTNFLILSMAITDFLLGFTIMPYSM 101
           +V + +F++  I + I GNL +++++ + +QL    TN+ I+S+A  D L+   +MP+  
Sbjct: 19  KVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGA 78

Query: 102 IRSVENCWYFGLTFCKIYYSFDLMLSITSIFHLCSVAIDRFYAIC-YPLLYSTKITIPVI 160
           I  V++ W +G  FC +  S D++L+  SIFHLC +++DR+YAIC  PL+Y  K+T   I
Sbjct: 79  IELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRI 138

Query: 161 KRLLLLCWSVPGAFAFGVVFSEAYADGIEGYDILV-------ACSSSCPVMFNKLWGTTL 213
             +L  CW +P   +F  +       GI   D++        + S+ C  M NK +  T 
Sbjct: 139 ALMLGGCWVIPTFISFLPIMQGWNNIGI--IDLIEKRKFNQNSNSTYCVFMVNKPYAITC 196

Query: 214 FMAGFFTPGSMMVGIYGKIFAVSRKHAHAINNLR--------------ENQNNQVKKDKK 259
            +  F+ P  +MV  Y +I+  +++HAH I  L+              ++  ++++ + K
Sbjct: 197 SVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHRMRTETK 256

Query: 260 AAKTLGIVIGVFLLCWFPCFFTILLDPFLNFSTPVVLFDALTWFGYFNSTCNPLIYGFFY 319
           AAKTL I++G F LCW P F T ++DPF++++ P  ++ A  W GY NS  NP +Y F  
Sbjct: 257 AAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWLGYINSGLNPFLYAFLN 316

Query: 320 PWFRRALKYIL 330
             FRRA   IL
Sbjct: 317 KSFRRAFLIIL 327


>gi|94421456 serotonin 5-HT4 receptor isoform d [Homo sapiens]
          Length = 360

 Score =  192 bits (489), Expect = 3e-49
 Identities = 105/311 (33%), Positives = 173/311 (55%), Gaps = 25/311 (8%)

Query: 43  RVAMYSFMAGSIFITIFGNLAMIISISYFKQLHT-PTNFLILSMAITDFLLGFTIMPYSM 101
           +V + +F++  I + I GNL +++++ + +QL    TN+ I+S+A  D L+   +MP+  
Sbjct: 19  KVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGA 78

Query: 102 IRSVENCWYFGLTFCKIYYSFDLMLSITSIFHLCSVAIDRFYAIC-YPLLYSTKITIPVI 160
           I  V++ W +G  FC +  S D++L+  SIFHLC +++DR+YAIC  PL+Y  K+T   I
Sbjct: 79  IELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRI 138

Query: 161 KRLLLLCWSVPGAFAFGVVFSEAYADGIEGYDILV-------ACSSSCPVMFNKLWGTTL 213
             +L  CW +P   +F  +       GI   D++        + S+ C  M NK +  T 
Sbjct: 139 ALMLGGCWVIPTFISFLPIMQGWNNIGI--IDLIEKRKFNQNSNSTYCVFMVNKPYAITC 196

Query: 214 FMAGFFTPGSMMVGIYGKIFAVSRKHAHAINNLR--------------ENQNNQVKKDKK 259
            +  F+ P  +MV  Y +I+  +++HAH I  L+              ++  ++++ + K
Sbjct: 197 SVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHRMRTETK 256

Query: 260 AAKTLGIVIGVFLLCWFPCFFTILLDPFLNFSTPVVLFDALTWFGYFNSTCNPLIYGFFY 319
           AAKTL I++G F LCW P F T ++DPF++++ P  ++ A  W GY NS  NP +Y F  
Sbjct: 257 AAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWLGYINSGLNPFLYAFLN 316

Query: 320 PWFRRALKYIL 330
             FRRA   IL
Sbjct: 317 KSFRRAFLIIL 327


>gi|94421454 serotonin 5-HT4 receptor isoform a [Homo sapiens]
          Length = 387

 Score =  192 bits (489), Expect = 3e-49
 Identities = 105/311 (33%), Positives = 173/311 (55%), Gaps = 25/311 (8%)

Query: 43  RVAMYSFMAGSIFITIFGNLAMIISISYFKQLHT-PTNFLILSMAITDFLLGFTIMPYSM 101
           +V + +F++  I + I GNL +++++ + +QL    TN+ I+S+A  D L+   +MP+  
Sbjct: 19  KVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGA 78

Query: 102 IRSVENCWYFGLTFCKIYYSFDLMLSITSIFHLCSVAIDRFYAIC-YPLLYSTKITIPVI 160
           I  V++ W +G  FC +  S D++L+  SIFHLC +++DR+YAIC  PL+Y  K+T   I
Sbjct: 79  IELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRI 138

Query: 161 KRLLLLCWSVPGAFAFGVVFSEAYADGIEGYDILV-------ACSSSCPVMFNKLWGTTL 213
             +L  CW +P   +F  +       GI   D++        + S+ C  M NK +  T 
Sbjct: 139 ALMLGGCWVIPTFISFLPIMQGWNNIGI--IDLIEKRKFNQNSNSTYCVFMVNKPYAITC 196

Query: 214 FMAGFFTPGSMMVGIYGKIFAVSRKHAHAINNLR--------------ENQNNQVKKDKK 259
            +  F+ P  +MV  Y +I+  +++HAH I  L+              ++  ++++ + K
Sbjct: 197 SVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHRMRTETK 256

Query: 260 AAKTLGIVIGVFLLCWFPCFFTILLDPFLNFSTPVVLFDALTWFGYFNSTCNPLIYGFFY 319
           AAKTL I++G F LCW P F T ++DPF++++ P  ++ A  W GY NS  NP +Y F  
Sbjct: 257 AAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWLGYINSGLNPFLYAFLN 316

Query: 320 PWFRRALKYIL 330
             FRRA   IL
Sbjct: 317 KSFRRAFLIIL 327


>gi|41282074 serotonin 5-HT4 receptor isoform g [Homo sapiens]
          Length = 378

 Score =  192 bits (489), Expect = 3e-49
 Identities = 105/311 (33%), Positives = 173/311 (55%), Gaps = 25/311 (8%)

Query: 43  RVAMYSFMAGSIFITIFGNLAMIISISYFKQLHT-PTNFLILSMAITDFLLGFTIMPYSM 101
           +V + +F++  I + I GNL +++++ + +QL    TN+ I+S+A  D L+   +MP+  
Sbjct: 19  KVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGA 78

Query: 102 IRSVENCWYFGLTFCKIYYSFDLMLSITSIFHLCSVAIDRFYAIC-YPLLYSTKITIPVI 160
           I  V++ W +G  FC +  S D++L+  SIFHLC +++DR+YAIC  PL+Y  K+T   I
Sbjct: 79  IELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRI 138

Query: 161 KRLLLLCWSVPGAFAFGVVFSEAYADGIEGYDILV-------ACSSSCPVMFNKLWGTTL 213
             +L  CW +P   +F  +       GI   D++        + S+ C  M NK +  T 
Sbjct: 139 ALMLGGCWVIPTFISFLPIMQGWNNIGI--IDLIEKRKFNQNSNSTYCVFMVNKPYAITC 196

Query: 214 FMAGFFTPGSMMVGIYGKIFAVSRKHAHAINNLR--------------ENQNNQVKKDKK 259
            +  F+ P  +MV  Y +I+  +++HAH I  L+              ++  ++++ + K
Sbjct: 197 SVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHRMRTETK 256

Query: 260 AAKTLGIVIGVFLLCWFPCFFTILLDPFLNFSTPVVLFDALTWFGYFNSTCNPLIYGFFY 319
           AAKTL I++G F LCW P F T ++DPF++++ P  ++ A  W GY NS  NP +Y F  
Sbjct: 257 AAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWLGYINSGLNPFLYAFLN 316

Query: 320 PWFRRALKYIL 330
             FRRA   IL
Sbjct: 317 KSFRRAFLIIL 327


>gi|11321563 serotonin 5-HT4 receptor isoform b [Homo sapiens]
          Length = 388

 Score =  192 bits (489), Expect = 3e-49
 Identities = 105/311 (33%), Positives = 173/311 (55%), Gaps = 25/311 (8%)

Query: 43  RVAMYSFMAGSIFITIFGNLAMIISISYFKQLHT-PTNFLILSMAITDFLLGFTIMPYSM 101
           +V + +F++  I + I GNL +++++ + +QL    TN+ I+S+A  D L+   +MP+  
Sbjct: 19  KVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGA 78

Query: 102 IRSVENCWYFGLTFCKIYYSFDLMLSITSIFHLCSVAIDRFYAIC-YPLLYSTKITIPVI 160
           I  V++ W +G  FC +  S D++L+  SIFHLC +++DR+YAIC  PL+Y  K+T   I
Sbjct: 79  IELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRI 138

Query: 161 KRLLLLCWSVPGAFAFGVVFSEAYADGIEGYDILV-------ACSSSCPVMFNKLWGTTL 213
             +L  CW +P   +F  +       GI   D++        + S+ C  M NK +  T 
Sbjct: 139 ALMLGGCWVIPTFISFLPIMQGWNNIGI--IDLIEKRKFNQNSNSTYCVFMVNKPYAITC 196

Query: 214 FMAGFFTPGSMMVGIYGKIFAVSRKHAHAINNLR--------------ENQNNQVKKDKK 259
            +  F+ P  +MV  Y +I+  +++HAH I  L+              ++  ++++ + K
Sbjct: 197 SVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHRMRTETK 256

Query: 260 AAKTLGIVIGVFLLCWFPCFFTILLDPFLNFSTPVVLFDALTWFGYFNSTCNPLIYGFFY 319
           AAKTL I++G F LCW P F T ++DPF++++ P  ++ A  W GY NS  NP +Y F  
Sbjct: 257 AAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWLGYINSGLNPFLYAFLN 316

Query: 320 PWFRRALKYIL 330
             FRRA   IL
Sbjct: 317 KSFRRAFLIIL 327


>gi|94421458 serotonin 5-HT4 receptor isoform hb [Homo sapiens]
          Length = 402

 Score =  191 bits (485), Expect = 8e-49
 Identities = 106/323 (32%), Positives = 174/323 (53%), Gaps = 35/323 (10%)

Query: 43  RVAMYSFMAGSIFITIFGNLAMIISISYFKQLHT-PTNFLILSMAITDFLLGFTIMPYSM 101
           +V + +F++  I + I GNL +++++ + +QL    TN+ I+S+A  D L+   +MP+  
Sbjct: 19  KVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGA 78

Query: 102 IRSVENCWYFGLTFCKIYYSFDLMLSITSIFHLCSVAIDRFYAIC-YPLLYSTKITIPVI 160
           I  V++ W +G  FC +  S D++L+  SIFHLC +++DR+YAIC  PL+Y  K+T   I
Sbjct: 79  IELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRI 138

Query: 161 KRLLLLCWSVPGAFAF----------GVVFSEAYADGIEGYDILV---------ACSSSC 201
             +L  CW +P   +F          G++  E   +   G D            + S+ C
Sbjct: 139 ALMLGGCWVIPTFISFLPIMQGWNNIGIIDLERSLNQGLGQDFHAIEKRKFNQNSNSTYC 198

Query: 202 PVMFNKLWGTTLFMAGFFTPGSMMVGIYGKIFAVSRKHAHAINNLR-------------- 247
             M NK +  T  +  F+ P  +MV  Y +I+  +++HAH I  L+              
Sbjct: 199 VFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSAD 258

Query: 248 ENQNNQVKKDKKAAKTLGIVIGVFLLCWFPCFFTILLDPFLNFSTPVVLFDALTWFGYFN 307
           ++  ++++ + KAAKTL I++G F LCW P F T ++DPF++++ P  ++ A  W GY N
Sbjct: 259 QHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWLGYIN 318

Query: 308 STCNPLIYGFFYPWFRRALKYIL 330
           S  NP +Y F    FRRA   IL
Sbjct: 319 SGLNPFLYAFLNKSFRRAFLIIL 341


>gi|111118990 alpha-1A-adrenergic receptor isoform 4 [Homo sapiens]
          Length = 455

 Score =  148 bits (374), Expect = 6e-36
 Identities = 93/345 (26%), Positives = 163/345 (47%), Gaps = 48/345 (13%)

Query: 24  NCSEYGNRSCPENERSLGVRVAMYSFMAGSIFITIFGNLAMIISISYFKQLHTPTNFLIL 83
           N S+  N + P    ++   + +   + G I   + GN+ +I+S++  + LH+ T++ I+
Sbjct: 7   NASDSSNCTQPPAPVNISKAILLGVILGGLILFGVLGNILVILSVACHRHLHSVTHYYIV 66

Query: 84  SMAITDFLLGFTIMPYSMIRSVENCWYFGLTFCKIYYSFDLMLSITSIFHLCSVAIDRFY 143
           ++A+ D LL  T++P+S I  V   W FG  FC I+ + D++    SI  LC ++IDR+ 
Sbjct: 67  NLAVADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYI 126

Query: 144 AICYPLLYSTKITIPVIKRLLLLCWSVPGAFAFGVVFSEAYADGIEGYDILVACSSSCPV 203
            + YPL Y T +T       LL  W++    + G +F               A       
Sbjct: 127 GVSYPLRYPTIVTQRRGLMALLCVWALSLVISIGPLFGWRQP----------APEDETIC 176

Query: 204 MFNKLWGTTLFMA--GFFTPGSMMVGIYGKIFAVSRKHAHAINN-------------LRE 248
             N+  G  LF A   F+ P ++++ +Y +++ V+++ +  + +             LR 
Sbjct: 177 QINEEPGYVLFSALGSFYLPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRI 236

Query: 249 NQNN----------------------QVKKDKKAAKTLGIVIGVFLLCWFPCFFTILLDP 286
           ++ N                      +  ++KKAAKTLGIV+G F+LCW P F  + +  
Sbjct: 237 HRKNAPAGGSGMASAKTKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGS 296

Query: 287 FL-NFSTPVVLFDALTWFGYFNSTCNPLIYGFFYPWFRRALKYIL 330
           F  +F     +F  + W GY NS  NP+IY      F++A + +L
Sbjct: 297 FFPDFKPSETVFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVL 341


>gi|111118992 alpha-1A-adrenergic receptor isoform 1 [Homo sapiens]
          Length = 466

 Score =  148 bits (374), Expect = 6e-36
 Identities = 93/345 (26%), Positives = 163/345 (47%), Gaps = 48/345 (13%)

Query: 24  NCSEYGNRSCPENERSLGVRVAMYSFMAGSIFITIFGNLAMIISISYFKQLHTPTNFLIL 83
           N S+  N + P    ++   + +   + G I   + GN+ +I+S++  + LH+ T++ I+
Sbjct: 7   NASDSSNCTQPPAPVNISKAILLGVILGGLILFGVLGNILVILSVACHRHLHSVTHYYIV 66

Query: 84  SMAITDFLLGFTIMPYSMIRSVENCWYFGLTFCKIYYSFDLMLSITSIFHLCSVAIDRFY 143
           ++A+ D LL  T++P+S I  V   W FG  FC I+ + D++    SI  LC ++IDR+ 
Sbjct: 67  NLAVADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYI 126

Query: 144 AICYPLLYSTKITIPVIKRLLLLCWSVPGAFAFGVVFSEAYADGIEGYDILVACSSSCPV 203
            + YPL Y T +T       LL  W++    + G +F               A       
Sbjct: 127 GVSYPLRYPTIVTQRRGLMALLCVWALSLVISIGPLFGWRQP----------APEDETIC 176

Query: 204 MFNKLWGTTLFMA--GFFTPGSMMVGIYGKIFAVSRKHAHAINN-------------LRE 248
             N+  G  LF A   F+ P ++++ +Y +++ V+++ +  + +             LR 
Sbjct: 177 QINEEPGYVLFSALGSFYLPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRI 236

Query: 249 NQNN----------------------QVKKDKKAAKTLGIVIGVFLLCWFPCFFTILLDP 286
           ++ N                      +  ++KKAAKTLGIV+G F+LCW P F  + +  
Sbjct: 237 HRKNAPAGGSGMASAKTKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGS 296

Query: 287 FL-NFSTPVVLFDALTWFGYFNSTCNPLIYGFFYPWFRRALKYIL 330
           F  +F     +F  + W GY NS  NP+IY      F++A + +L
Sbjct: 297 FFPDFKPSETVFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVL 341


>gi|111118986 alpha-1A-adrenergic receptor isoform 2 [Homo sapiens]
          Length = 475

 Score =  148 bits (374), Expect = 6e-36
 Identities = 93/345 (26%), Positives = 163/345 (47%), Gaps = 48/345 (13%)

Query: 24  NCSEYGNRSCPENERSLGVRVAMYSFMAGSIFITIFGNLAMIISISYFKQLHTPTNFLIL 83
           N S+  N + P    ++   + +   + G I   + GN+ +I+S++  + LH+ T++ I+
Sbjct: 7   NASDSSNCTQPPAPVNISKAILLGVILGGLILFGVLGNILVILSVACHRHLHSVTHYYIV 66

Query: 84  SMAITDFLLGFTIMPYSMIRSVENCWYFGLTFCKIYYSFDLMLSITSIFHLCSVAIDRFY 143
           ++A+ D LL  T++P+S I  V   W FG  FC I+ + D++    SI  LC ++IDR+ 
Sbjct: 67  NLAVADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYI 126

Query: 144 AICYPLLYSTKITIPVIKRLLLLCWSVPGAFAFGVVFSEAYADGIEGYDILVACSSSCPV 203
            + YPL Y T +T       LL  W++    + G +F               A       
Sbjct: 127 GVSYPLRYPTIVTQRRGLMALLCVWALSLVISIGPLFGWRQP----------APEDETIC 176

Query: 204 MFNKLWGTTLFMA--GFFTPGSMMVGIYGKIFAVSRKHAHAINN-------------LRE 248
             N+  G  LF A   F+ P ++++ +Y +++ V+++ +  + +             LR 
Sbjct: 177 QINEEPGYVLFSALGSFYLPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRI 236

Query: 249 NQNN----------------------QVKKDKKAAKTLGIVIGVFLLCWFPCFFTILLDP 286
           ++ N                      +  ++KKAAKTLGIV+G F+LCW P F  + +  
Sbjct: 237 HRKNAPAGGSGMASAKTKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGS 296

Query: 287 FL-NFSTPVVLFDALTWFGYFNSTCNPLIYGFFYPWFRRALKYIL 330
           F  +F     +F  + W GY NS  NP+IY      F++A + +L
Sbjct: 297 FFPDFKPSETVFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVL 341


>gi|111118988 alpha-1A-adrenergic receptor isoform 3 [Homo sapiens]
          Length = 429

 Score =  148 bits (374), Expect = 6e-36
 Identities = 93/345 (26%), Positives = 163/345 (47%), Gaps = 48/345 (13%)

Query: 24  NCSEYGNRSCPENERSLGVRVAMYSFMAGSIFITIFGNLAMIISISYFKQLHTPTNFLIL 83
           N S+  N + P    ++   + +   + G I   + GN+ +I+S++  + LH+ T++ I+
Sbjct: 7   NASDSSNCTQPPAPVNISKAILLGVILGGLILFGVLGNILVILSVACHRHLHSVTHYYIV 66

Query: 84  SMAITDFLLGFTIMPYSMIRSVENCWYFGLTFCKIYYSFDLMLSITSIFHLCSVAIDRFY 143
           ++A+ D LL  T++P+S I  V   W FG  FC I+ + D++    SI  LC ++IDR+ 
Sbjct: 67  NLAVADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYI 126

Query: 144 AICYPLLYSTKITIPVIKRLLLLCWSVPGAFAFGVVFSEAYADGIEGYDILVACSSSCPV 203
            + YPL Y T +T       LL  W++    + G +F               A       
Sbjct: 127 GVSYPLRYPTIVTQRRGLMALLCVWALSLVISIGPLFGWRQP----------APEDETIC 176

Query: 204 MFNKLWGTTLFMA--GFFTPGSMMVGIYGKIFAVSRKHAHAINN-------------LRE 248
             N+  G  LF A   F+ P ++++ +Y +++ V+++ +  + +             LR 
Sbjct: 177 QINEEPGYVLFSALGSFYLPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRI 236

Query: 249 NQNN----------------------QVKKDKKAAKTLGIVIGVFLLCWFPCFFTILLDP 286
           ++ N                      +  ++KKAAKTLGIV+G F+LCW P F  + +  
Sbjct: 237 HRKNAPAGGSGMASAKTKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGS 296

Query: 287 FL-NFSTPVVLFDALTWFGYFNSTCNPLIYGFFYPWFRRALKYIL 330
           F  +F     +F  + W GY NS  NP+IY      F++A + +L
Sbjct: 297 FFPDFKPSETVFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVL 341


>gi|197085610 histamine receptor H2 isoform 1 [Homo sapiens]
          Length = 397

 Score =  145 bits (367), Expect = 4e-35
 Identities = 93/310 (30%), Positives = 156/310 (50%), Gaps = 10/310 (3%)

Query: 39  SLGVRVAMYSFMAGSIFITIFGNLAMIISISYFKQLHTPTNFLILSMAITDFLLGFTIMP 98
           S   ++ +   +A  I IT+ GN+ + +++   ++L   TN  I+S+AITD LLG  ++P
Sbjct: 14  STACKITITVVLAVLILITVAGNVVVCLAVGLNRRLRNLTNCFIVSLAITDLLLGLLVLP 73

Query: 99  YSMIRSVENCWYFGLTFCKIYYSFDLMLSITSIFHLCSVAIDRFYAICYPLLYSTKITIP 158
           +S I  +   W FG  FC IY S D+ML   SI +L  +++DR+ A+  PL Y   +T  
Sbjct: 74  FSAIYQLSCKWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCAVMDPLRYPVLVTPV 133

Query: 159 VIKRLLLLCWSVPGAFAFGVVFS--EAYADGIEGYDILVACSSSCPVMFNKLWGTTLFMA 216
            +   L+L W +    +F  +     +  +  +G       +S C V  N+++G    + 
Sbjct: 134 RVAISLVLIWVISITLSFLSIHLGWNSRNETSKGNH----TTSKCKVQVNEVYGLVDGLV 189

Query: 217 GFFTPGSMMVGIYGKIFAVSRKHAHAINNLRENQNNQVKKDKKAAKTLGIVIGVFLLCWF 276
            F+ P  +M   Y +IF V+R  A  IN++   +   + ++ KA  TL  V+G F++CWF
Sbjct: 190 TFYLPLLIMCITYYRIFKVARDQAKRINHISSWKAATI-REHKATVTLAAVMGAFIICWF 248

Query: 277 PCFFTILLDPFLNFSTPV--VLFDALTWFGYFNSTCNPLIYGFFYPWFRRALKYILLGKI 334
           P +FT  +   L     +  VL   + W GY NS  NP++Y      FR   + +   ++
Sbjct: 249 P-YFTAFVYRGLRGDDAINEVLEAIVLWLGYANSALNPILYAALNRDFRTGYQQLFCCRL 307

Query: 335 FSSCFHNTIL 344
            +   H T L
Sbjct: 308 ANRNSHKTSL 317


>gi|13435405 histamine receptor H2 isoform 2 [Homo sapiens]
          Length = 359

 Score =  145 bits (367), Expect = 4e-35
 Identities = 93/310 (30%), Positives = 156/310 (50%), Gaps = 10/310 (3%)

Query: 39  SLGVRVAMYSFMAGSIFITIFGNLAMIISISYFKQLHTPTNFLILSMAITDFLLGFTIMP 98
           S   ++ +   +A  I IT+ GN+ + +++   ++L   TN  I+S+AITD LLG  ++P
Sbjct: 14  STACKITITVVLAVLILITVAGNVVVCLAVGLNRRLRNLTNCFIVSLAITDLLLGLLVLP 73

Query: 99  YSMIRSVENCWYFGLTFCKIYYSFDLMLSITSIFHLCSVAIDRFYAICYPLLYSTKITIP 158
           +S I  +   W FG  FC IY S D+ML   SI +L  +++DR+ A+  PL Y   +T  
Sbjct: 74  FSAIYQLSCKWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCAVMDPLRYPVLVTPV 133

Query: 159 VIKRLLLLCWSVPGAFAFGVVFS--EAYADGIEGYDILVACSSSCPVMFNKLWGTTLFMA 216
            +   L+L W +    +F  +     +  +  +G       +S C V  N+++G    + 
Sbjct: 134 RVAISLVLIWVISITLSFLSIHLGWNSRNETSKGNH----TTSKCKVQVNEVYGLVDGLV 189

Query: 217 GFFTPGSMMVGIYGKIFAVSRKHAHAINNLRENQNNQVKKDKKAAKTLGIVIGVFLLCWF 276
            F+ P  +M   Y +IF V+R  A  IN++   +   + ++ KA  TL  V+G F++CWF
Sbjct: 190 TFYLPLLIMCITYYRIFKVARDQAKRINHISSWKAATI-REHKATVTLAAVMGAFIICWF 248

Query: 277 PCFFTILLDPFLNFSTPV--VLFDALTWFGYFNSTCNPLIYGFFYPWFRRALKYILLGKI 334
           P +FT  +   L     +  VL   + W GY NS  NP++Y      FR   + +   ++
Sbjct: 249 P-YFTAFVYRGLRGDDAINEVLEAIVLWLGYANSALNPILYAALNRDFRTGYQQLFCCRL 307

Query: 335 FSSCFHNTIL 344
            +   H T L
Sbjct: 308 ANRNSHKTSL 317


>gi|4501959 alpha-1B-adrenergic receptor [Homo sapiens]
          Length = 520

 Score =  145 bits (365), Expect = 7e-35
 Identities = 91/340 (26%), Positives = 157/340 (46%), Gaps = 49/340 (14%)

Query: 30  NRSCPENERSLGVRVAMYSFMAGSIFITIFGNLAMIISISYFKQLHTPTNFLILSMAITD 89
           N + P+ + +  + V +   +   I   I GN+ +I+S++  + L TPTN+ I+++A+ D
Sbjct: 34  NSTLPQLDITRAISVGLV--LGAFILFAIVGNILVILSVACNRHLRTPTNYFIVNLAMAD 91

Query: 90  FLLGFTIMPYSMIRSVENCWYFGLTFCKIYYSFDLMLSITSIFHLCSVAIDRFYAICYPL 149
            LL FT++P+S    V   W  G  FC I+ + D++    SI  LC+++IDR+  + Y L
Sbjct: 92  LLLSFTVLPFSAALEVLGYWVLGRIFCDIWAAVDVLCCTASILSLCAISIDRYIGVRYSL 151

Query: 150 LYSTKITIPVIKRLLLLCWSVPGAFAFGVVFSEAYADGIEGYDILVACSSSCPVMFNKLW 209
            Y T +T       LL  W +    + G +    + +     D        C V     +
Sbjct: 152 QYPTLVTRRKAILALLSVWVLSTVISIGPLL--GWKEPAPNDD------KECGVTEEPFY 203

Query: 210 GTTLFMAGFFTPGSMMVGIYGKIFAVSRK----------------------------HAH 241
                +  F+ P ++++ +Y +++ V+++                            H  
Sbjct: 204 ALFSSLGSFYIPLAVILVMYCRVYIVAKRTTKNLEAGVMKEMSNSKELTLRIHSKNFHED 263

Query: 242 AINNLRENQNN----------QVKKDKKAAKTLGIVIGVFLLCWFPCFFTILLDP-FLNF 290
            +++ +   +N          +  ++KKAAKTLGIV+G+F+LCW P F  + L   F   
Sbjct: 264 TLSSTKAKGHNPRSSIAVKLFKFSREKKAAKTLGIVVGMFILCWLPFFIALPLGSLFSTL 323

Query: 291 STPVVLFDALTWFGYFNSTCNPLIYGFFYPWFRRALKYIL 330
             P  +F  + W GYFNS  NP+IY      F+RA   IL
Sbjct: 324 KPPDAVFKVVFWLGYFNSCLNPIIYPCSSKEFKRAFVRIL 363


>gi|4503383 dopamine receptor D1 [Homo sapiens]
          Length = 446

 Score =  142 bits (359), Expect = 3e-34
 Identities = 90/333 (27%), Positives = 156/333 (46%), Gaps = 43/333 (12%)

Query: 37  ERSLGVRVAMYSFMAGSIFITIFGNLAMIISISYFKQLHTP-TNFLILSMAITDFLLGFT 95
           ER   VR+    F++  I  T+ GN  +  ++  F+ L +  TNF ++S+A++D L+   
Sbjct: 17  ERDFSVRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVL 76

Query: 96  IMPYSMIRSVENCWYFGLTFCKIYYSFDLMLSITSIFHLCSVAIDRFYAICYPLLYSTKI 155
           +MP+  +  +   W FG +FC I+ +FD+M S  SI +LC +++DR++AI  P  Y  K+
Sbjct: 77  VMPWKAVAEIAGFWPFG-SFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKM 135

Query: 156 TIPVIKRLLLLCWS-------VPGAFAFGVVFSEAYADGIEGYDILVACSSSCPVMFNKL 208
           T      L+ + W+       +P   ++      + +DG      L     +C    ++ 
Sbjct: 136 TPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTSPSDG--NATSLAETIDNCDSSLSRT 193

Query: 209 WGTTLFMAGFFTPGSMMVGIYGKIFAVSRKH-----------AHAINNLRENQNNQ---- 253
           +  +  +  F+ P ++M+  Y +I+ +++K             HA N      N +    
Sbjct: 194 YAISSSVISFYIPVAIMIVTYTRIYRIAQKQIRRIAALERAAVHAKNCQTTTGNGKPVEC 253

Query: 254 ----------VKKDKKAAKTLGIVIGVFLLCWFPCFFTILLDPFLN------FSTPVVLF 297
                      K++ K  KTL +++GVF+ CW P F    + PF        F      F
Sbjct: 254 SQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCILPFCGSGETQPFCIDSNTF 313

Query: 298 DALTWFGYFNSTCNPLIYGFFYPWFRRALKYIL 330
           D   WFG+ NS+ NP+IY F    FR+A   +L
Sbjct: 314 DVFVWFGWANSSLNPIIYAFNAD-FRKAFSTLL 345


>gi|4504535 5-hydroxytryptamine (serotonin) receptor 1D [Homo
           sapiens]
          Length = 377

 Score =  141 bits (355), Expect = 1e-33
 Identities = 98/367 (26%), Positives = 162/367 (44%), Gaps = 62/367 (16%)

Query: 17  QTKKEKFNCSEYGNRSCPENERSLGVRVAMYSFMAGSIFITIFGNLAMIISISYFKQLHT 76
           +      N +E      P   ++L + +A+   ++     T+  N  ++ +I   ++LHT
Sbjct: 14  EASNRSLNATETSEAWDPRTLQALKISLAVV--LSVITLATVLSNAFVLTTILLTRKLHT 71

Query: 77  PTNFLILSMAITDFLLGFTIMPYSMIRSVENCWYFGLTFCKIYYSFDLMLSITSIFHLCS 136
           P N+LI S+A TD L+   +MP S+  ++ + W FG   C I+ S D+     SI HLC 
Sbjct: 72  PANYLIGSLATTDLLVSILVMPISIAYTITHTWNFGQILCDIWLSSDITCCTASILHLCV 131

Query: 137 VAIDRFYAICYPLLYSTKITIPVIKRLLLLCWSVPGAFAFGVVFSEAYADGIEGYDILVA 196
           +A+DR++AI   L YS + T      ++ + W++    +   +F        E  D LV 
Sbjct: 132 IALDRYWAITDALEYSKRRTAGHAATMIAIVWAISICISIPPLFWRQAKAQEEMSDCLVN 191

Query: 197 CSSSCPVMFNKLWGTTLFMAGFFTPGSMMVGIYGKIFAVSRKH--------------AHA 242
            S     +++           F+ P  +++ +YG+I+  +R                AH 
Sbjct: 192 TSQISYTIYST-------CGAFYIPSVLLIILYGRIYRAARNRILNPPSLYGKRFTTAHL 244

Query: 243 I------------NNLRENQN---------NQVK----------------KDKKAAKTLG 265
           I            ++L E  +         N VK                +++KA K LG
Sbjct: 245 ITGSAGSSLCSLNSSLHEGHSHSAGSPLFFNHVKIKLADSALERKRISAARERKATKILG 304

Query: 266 IVIGVFLLCWFPCFFTILLDPFLNFSTPV--VLFDALTWFGYFNSTCNPLIYGFFYPWFR 323
           I++G F++CW P F   L+ P    S  +   LFD  TW GY NS  NP+IY  F   FR
Sbjct: 305 IILGAFIICWLPFFVVSLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFR 364

Query: 324 RALKYIL 330
           +A + I+
Sbjct: 365 QAFQKIV 371


>gi|4501969 adrenergic, beta-2-, receptor, surface [Homo sapiens]
          Length = 413

 Score =  139 bits (349), Expect = 5e-33
 Identities = 88/308 (28%), Positives = 148/308 (48%), Gaps = 22/308 (7%)

Query: 44  VAMYSFMAGSIFITIFGNLAMIISISYFKQLHTPTNFLILSMAITDFLLGFTIMPYSMIR 103
           V M   M+  +   +FGN+ +I +I+ F++L T TN+ I S+A  D ++G  ++P+    
Sbjct: 34  VGMGIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGAAH 93

Query: 104 SVENCWYFGLTFCKIYYSFDLMLSITSIFHLCSVAIDRFYAICYPLLYSTKITIPVIKRL 163
            +   W FG  +C+ + S D++    SI  LC +A+DR++AI  P  Y + +T    + +
Sbjct: 94  ILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVI 153

Query: 164 LLLCWSVPGAFAFGVVFSEAYADGIEGYDILVACSSSCPVMFNKLWGTTLFMAGFFTPGS 223
           +L+ W V G  +F  +    Y    +      A  + C    N+ +     +  F+ P  
Sbjct: 154 ILMVWIVSGLTSFLPIQMHWYRATHQEAINCYANETCCDFFTNQAYAIASSIVSFYVPLV 213

Query: 224 MMVGIYGKIFAVSRKHAHAINNLREN---QN-NQVK-----------------KDKKAAK 262
           +MV +Y ++F  +++    I+        QN +QV+                 K+ KA K
Sbjct: 214 IMVFVYSRVFQEAKRQLQKIDKSEGRFHVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALK 273

Query: 263 TLGIVIGVFLLCWFPCFFTILLDPFLNFSTPVVLFDALTWFGYFNSTCNPLIYGFFYPWF 322
           TLGI++G F LCW P F   ++    +      ++  L W GY NS  NPLIY    P F
Sbjct: 274 TLGIIMGTFTLCWLPFFIVNIVHVIQDNLIRKEVYILLNWIGYVNSGFNPLIY-CRSPDF 332

Query: 323 RRALKYIL 330
           R A + +L
Sbjct: 333 RIAFQELL 340


>gi|10880131 5-hydroxytryptamine receptor 7 isoform b [Homo sapiens]
          Length = 432

 Score =  131 bits (330), Expect = 8e-31
 Identities = 87/330 (26%), Positives = 154/330 (46%), Gaps = 53/330 (16%)

Query: 43  RVAMYSFMAGSIFITIFGNLAMIISISYFKQLHTPTNFLILSMAITDFLLGFTIMPY-SM 101
           +V + S +     +TI GN  ++IS+ + K+L  P+N+LI+S+A+ D  +   +MP+ S+
Sbjct: 81  KVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAVMPFVSV 140

Query: 102 IRSVENCWYFGLTFCKIYYSFDLMLSITSIFHLCSVAIDRFYAICYPLLYSTKITIPVIK 161
              +   W FG  FC ++ + D+M    SI  LC ++IDR+  I  PL Y  +     + 
Sbjct: 141 TDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMA 200

Query: 162 RLLLLCWSVPGAFAFGVVFSEAYADGIEGYDILVACSSSCPVMFNKLWGTTLF--MAGFF 219
           +++L  W +  +     +F   +A  +    +          + ++ +G T++     F+
Sbjct: 201 KMILSVWLLSASITLPPLF--GWAQNVNDDKV---------CLISQDFGYTIYSTAVAFY 249

Query: 220 TPGSMMVGIYGKIFAVSRKHAH----------------AINNL----------------- 246
            P S+M+ +Y +I+  +RK A                 A+N +                 
Sbjct: 250 IPMSVMLFMYYQIYKAARKSAAKHKFPGFPRVEPDSVIALNGIVKLQKEVEECANLSRLL 309

Query: 247 -RENQNNQV-KKDKKAAKTLGIVIGVFLLCWFPCFFTILLDPFLNFST----PVVLFDAL 300
             E +N  + K+++KAA TLGI++G F +CW P F      PF+  ++    P+ +    
Sbjct: 310 KHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSCIPLWVERTF 369

Query: 301 TWFGYFNSTCNPLIYGFFYPWFRRALKYIL 330
            W GY NS  NP IY FF    R   + +L
Sbjct: 370 LWLGYANSLINPFIYAFFNRDLRTTYRSLL 399


>gi|10880129 5-hydroxytryptamine receptor 7 isoform d [Homo sapiens]
          Length = 479

 Score =  131 bits (330), Expect = 8e-31
 Identities = 87/330 (26%), Positives = 154/330 (46%), Gaps = 53/330 (16%)

Query: 43  RVAMYSFMAGSIFITIFGNLAMIISISYFKQLHTPTNFLILSMAITDFLLGFTIMPY-SM 101
           +V + S +     +TI GN  ++IS+ + K+L  P+N+LI+S+A+ D  +   +MP+ S+
Sbjct: 81  KVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAVMPFVSV 140

Query: 102 IRSVENCWYFGLTFCKIYYSFDLMLSITSIFHLCSVAIDRFYAICYPLLYSTKITIPVIK 161
              +   W FG  FC ++ + D+M    SI  LC ++IDR+  I  PL Y  +     + 
Sbjct: 141 TDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMA 200

Query: 162 RLLLLCWSVPGAFAFGVVFSEAYADGIEGYDILVACSSSCPVMFNKLWGTTLF--MAGFF 219
           +++L  W +  +     +F   +A  +    +          + ++ +G T++     F+
Sbjct: 201 KMILSVWLLSASITLPPLF--GWAQNVNDDKV---------CLISQDFGYTIYSTAVAFY 249

Query: 220 TPGSMMVGIYGKIFAVSRKHAH----------------AINNL----------------- 246
            P S+M+ +Y +I+  +RK A                 A+N +                 
Sbjct: 250 IPMSVMLFMYYQIYKAARKSAAKHKFPGFPRVEPDSVIALNGIVKLQKEVEECANLSRLL 309

Query: 247 -RENQNNQV-KKDKKAAKTLGIVIGVFLLCWFPCFFTILLDPFLNFST----PVVLFDAL 300
             E +N  + K+++KAA TLGI++G F +CW P F      PF+  ++    P+ +    
Sbjct: 310 KHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSCIPLWVERTF 369

Query: 301 TWFGYFNSTCNPLIYGFFYPWFRRALKYIL 330
            W GY NS  NP IY FF    R   + +L
Sbjct: 370 LWLGYANSLINPFIYAFFNRDLRTTYRSLL 399


>gi|4504547 5-hydroxytryptamine receptor 7 isoform a [Homo sapiens]
          Length = 445

 Score =  131 bits (330), Expect = 8e-31
 Identities = 87/330 (26%), Positives = 154/330 (46%), Gaps = 53/330 (16%)

Query: 43  RVAMYSFMAGSIFITIFGNLAMIISISYFKQLHTPTNFLILSMAITDFLLGFTIMPY-SM 101
           +V + S +     +TI GN  ++IS+ + K+L  P+N+LI+S+A+ D  +   +MP+ S+
Sbjct: 81  KVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAVMPFVSV 140

Query: 102 IRSVENCWYFGLTFCKIYYSFDLMLSITSIFHLCSVAIDRFYAICYPLLYSTKITIPVIK 161
              +   W FG  FC ++ + D+M    SI  LC ++IDR+  I  PL Y  +     + 
Sbjct: 141 TDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMA 200

Query: 162 RLLLLCWSVPGAFAFGVVFSEAYADGIEGYDILVACSSSCPVMFNKLWGTTLF--MAGFF 219
           +++L  W +  +     +F   +A  +    +          + ++ +G T++     F+
Sbjct: 201 KMILSVWLLSASITLPPLF--GWAQNVNDDKV---------CLISQDFGYTIYSTAVAFY 249

Query: 220 TPGSMMVGIYGKIFAVSRKHAH----------------AINNL----------------- 246
            P S+M+ +Y +I+  +RK A                 A+N +                 
Sbjct: 250 IPMSVMLFMYYQIYKAARKSAAKHKFPGFPRVEPDSVIALNGIVKLQKEVEECANLSRLL 309

Query: 247 -RENQNNQV-KKDKKAAKTLGIVIGVFLLCWFPCFFTILLDPFLNFST----PVVLFDAL 300
             E +N  + K+++KAA TLGI++G F +CW P F      PF+  ++    P+ +    
Sbjct: 310 KHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSCIPLWVERTF 369

Query: 301 TWFGYFNSTCNPLIYGFFYPWFRRALKYIL 330
            W GY NS  NP IY FF    R   + +L
Sbjct: 370 LWLGYANSLINPFIYAFFNRDLRTTYRSLL 399


>gi|4504537 5-hydroxytryptamine (serotonin) receptor 1E [Homo
           sapiens]
          Length = 365

 Score =  125 bits (313), Expect = 7e-29
 Identities = 85/332 (25%), Positives = 147/332 (44%), Gaps = 64/332 (19%)

Query: 56  ITIFGNLAMIISISYFKQLHTPTNFLILSMAITDFLLGFTIMPYSMIRSVENCWYFGLTF 115
           +T   NLA+I++I   K+LH P N+LI S+A+TD L+   +MP S+I  V + W  G   
Sbjct: 35  LTTLLNLAVIMAIGTTKKLHQPANYLICSLAVTDLLVAVLVMPLSIIYIVMDRWKLGYFL 94

Query: 116 CKIYYSFDLMLSITSIFHLCSVAIDRFYAICYPLLYSTKITIPVIKRLLLLCWSVPGAFA 175
           C+++ S D+     SI HLC +A+DR++AI   + Y+ K T      ++L  W++    +
Sbjct: 95  CEVWLSVDMTCCTCSILHLCVIALDRYWAITNAIEYARKRTAKRAALMILTVWTISIFIS 154

Query: 176 FGVVFSEAYADGIEGYDILVACSSSCPVMFNKLWGTTLFMAG-FFTPGSMMVGIYGKIFA 234
              +F  ++         L    S C +  + +  T     G F+ P ++++ +Y +I+ 
Sbjct: 155 MPPLFWRSHRR-------LSPPPSQCTIQHDHVIYTIYSTLGAFYIPLTLILILYYRIYH 207

Query: 235 VSR-------KHAHAINNLRENQNN----------------------------------- 252
            ++          H  N   ++QN+                                   
Sbjct: 208 AAKSLYQKRGSSRHLSNRSTDSQNSFASCKLTQTFCVSDFSTSDPTTEFEKFHASIRIPP 267

Query: 253 --------------QVKKDKKAAKTLGIVIGVFLLCWFPCFFTILLDPFLNFSTPVVLFD 298
                            +++KAA+ LG+++G F+L W P F   L+     ++    + D
Sbjct: 268 FDNDLDHPGERQQISSTRERKAARILGLILGAFILSWLPFFIKELIVGLSIYTVSSEVAD 327

Query: 299 ALTWFGYFNSTCNPLIYGFFYPWFRRALKYIL 330
            LTW GY NS  NPL+Y  F   F+ A K ++
Sbjct: 328 FLTWLGYVNSLINPLLYTSFNEDFKLAFKKLI 359


>gi|4557267 adrenergic, beta-3-, receptor [Homo sapiens]
          Length = 408

 Score =  121 bits (303), Expect = 1e-27
 Identities = 84/322 (26%), Positives = 143/322 (44%), Gaps = 42/322 (13%)

Query: 48  SFMAGSIFITIFGNLAMIISISYFKQLHTPTNFLILSMAITDFLLGFTIMPYSMIRSVEN 107
           + +A ++  T+ GNL +I++I++  +L T TN  + S+A  D ++G  ++P +   ++  
Sbjct: 42  ALLALAVLATVGGNLLVIVAIAWTPRLQTMTNVFVTSLAAADLVMGLLVVPPAATLALTG 101

Query: 108 CWYFGLTFCKIYYSFDLMLSITSIFHLCSVAIDRFYAICYPLLYSTKITIPVIKRLLLLC 167
            W  G T C+++ S D++    SI  LC++A+DR+ A+  PL Y   +T    +  ++L 
Sbjct: 102 HWPLGATGCELWTSVDVLCVTASIETLCALAVDRYLAVTNPLRYGALVTKRCARTAVVLV 161

Query: 168 WSVPGAFAFGVVFSEAYADGIEGYDILVACSSS---CPVMFNKLWGTTLFMAGFFTPGSM 224
           W V  A +F  + S+ +  G +       C S+   C    N  +        F+ P  +
Sbjct: 162 WVVSAAVSFAPIMSQWWRVGADAE--AQRCHSNPRCCAFASNMPYVLLSSSVSFYLPLLV 219

Query: 225 MVGIYGKIFAVSRKHAHAINNL-----------------------------------REN 249
           M+ +Y ++F V+ +    +                                      R  
Sbjct: 220 MLFVYARVFVVATRQLRLLRGELGRFPPEESPPAPSRSLAPAPVGTCAPPEGVPACGRRP 279

Query: 250 QNNQVKKDKKAAKTLGIVIGVFLLCWFPCFFTILLDPFLNFS-TPVVLFDALTWFGYFNS 308
                 ++ +A  TLG+++G F LCW P F   +L      S  P   F AL W GY NS
Sbjct: 280 ARLLPLREHRALCTLGLIMGTFTLCWLPFFLANVLRALGGPSLVPGPAFLALNWLGYANS 339

Query: 309 TCNPLIYGFFYPWFRRALKYIL 330
             NPLIY    P FR A + +L
Sbjct: 340 AFNPLIY-CRSPDFRSAFRRLL 360


>gi|16604258 neuropeptide FF receptor 2 isoform 2 [Homo sapiens]
          Length = 420

 Score =  119 bits (297), Expect = 5e-27
 Identities = 83/292 (28%), Positives = 140/292 (47%), Gaps = 22/292 (7%)

Query: 55  FITIFGNLAMIISISYFKQLHTPTNFLILSMAITDFLLGFTIMPYSMIRSVENCWYFGLT 114
           F+ + GN  +   +   K +HT TN  IL++AI+D L+G   MP +++ ++   W FG T
Sbjct: 57  FLCMMGNTVVCFIVMRNKHMHTVTNLFILNLAISDLLVGIFCMPITLLDNIIAGWPFGNT 116

Query: 115 FCKIYYSFDLMLSITSIFHLCSVAIDRFYAICYPLLYSTKITIPVIKRLLLLCWSV---- 170
            CKI      +    S+F L ++A+DRF  + YP  +  K+TI     ++++ W +    
Sbjct: 117 MCKISGLVQGISVAASVFTLVAIAVDRFQCVVYP--FKPKLTIKTAFVIIMIIWVLAITI 174

Query: 171 --PGAFAFGVVFSEAYADGIEGYD---ILVACSSSCPVM-FNKLWGTTLFMAGFFTPGSM 224
             P A    V   + Y   +   +    +  C    P     K++ T LF   +  P S+
Sbjct: 175 MSPSAVMLHVQEEKYYRVRLNSQNKTSPVYWCREDWPNQEMRKIYTTVLFANIYLAPLSL 234

Query: 225 MVGIYGKIFAVSRKHAHAINNLRENQNN---QVKKDKKAAKTLGIVIGVFLLCWFPCFFT 281
           +V +YG+I  +S   A   +  R+NQ       +K +K  K L IV  +F+L W P +  
Sbjct: 235 IVIMYGRI-GISLFRAAVPHTGRKNQEQWHVVSRKKQKIIKMLLIVALLFILSWLPLWTL 293

Query: 282 ILLDPFLNFS------TPVVLFDALTWFGYFNSTCNPLIYGFFYPWFRRALK 327
           ++L  + + S        + ++    W  + NS+ NP+IYGFF   FRR  +
Sbjct: 294 MMLSDYADLSPNELQIINIYIYPFAHWLAFGNSSVNPIIYGFFNENFRRGFQ 345


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.331    0.142    0.460 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,156,558
Number of Sequences: 37866
Number of extensions: 483556
Number of successful extensions: 3264
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 581
Number of HSP's successfully gapped in prelim test: 149
Number of HSP's that attempted gapping in prelim test: 1790
Number of HSP's gapped (non-prelim): 935
length of query: 351
length of database: 18,247,518
effective HSP length: 103
effective length of query: 248
effective length of database: 14,347,320
effective search space: 3558135360
effective search space used: 3558135360
T: 11
A: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.