Search of human proteins with 71896723

Search of human proteins with 71896723

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|71896723 ceramide kinase-like isoform b [Homo sapiens]
         (558 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|71896723 ceramide kinase-like isoform b [Homo sapiens]            1126   0.0  
gi|41680688 ceramide kinase-like isoform a [Homo sapiens]            1057   0.0  
gi|237757361 ceramide kinase-like isoform g [Homo sapiens]           1018   0.0  
gi|71896725 ceramide kinase-like isoform c [Homo sapiens]             533   e-151
gi|71896711 ceramide kinase-like isoform d [Homo sapiens]             529   e-150
gi|20336726 ceramide kinase [Homo sapiens]                            195   1e-49
gi|8922701 acylglycerol kinase [Homo sapiens]                          57   4e-08
gi|217272885 sphingosine kinase 1 isoform 3 [Homo sapiens]             54   4e-07
gi|217272883 sphingosine kinase 1 isoform 3 [Homo sapiens]             54   4e-07
gi|21361088 sphingosine kinase 1 isoform 1 [Homo sapiens]              54   4e-07
gi|217272880 sphingosine kinase 1 isoform 2 [Homo sapiens]             54   4e-07
gi|21361699 sphingosine kinase 2 [Homo sapiens]                        52   1e-06
gi|48255900 SWI/SNF-related matrix-associated actin-dependent re...    33   0.53 
gi|48255898 SWI/SNF-related matrix-associated actin-dependent re...    33   0.53 
gi|39930469 brix domain containing 1 [Homo sapiens]                    32   2.0  
gi|4502897 cleft lip and palate associated transmembrane protein...    32   2.0  
gi|157694487 CMT1A duplicated region transcript 1 [Homo sapiens]       31   3.4  
gi|51093832 GTPase activating protein and VPS9 domains 1 [Homo s...    30   4.5  
gi|33356148 formin-like 1 [Homo sapiens]                               30   4.5  
gi|7661950 SH2 domain binding protein 1 [Homo sapiens]                 30   5.8  
gi|239753057 PREDICTED: hypothetical protein XP_002345334 [Homo ...    29   10.0 
gi|239747608 PREDICTED: hypothetical protein [Homo sapiens]            29   10.0 
gi|239741483 PREDICTED: hypothetical protein XP_002342212 [Homo ...    29   10.0 
gi|33598960 alpha-2B-adrenergic receptor [Homo sapiens]                29   10.0 
gi|62243658 PI-3-kinase-related kinase SMG-1 [Homo sapiens]            29   10.0 
gi|11055976 carbohydrate (N-acetylglucosamine 6-O) sulfotransfer...    29   10.0 

>gi|71896723 ceramide kinase-like isoform b [Homo sapiens]
          Length = 558

 Score = 1126 bits (2913), Expect = 0.0
 Identities = 558/558 (100%), Positives = 558/558 (100%)

Query: 1   MPWRRRRNRVSALEGGREEEAPPEAAAVPPALLTSPQQTEAAAERILLRGIFEIGRDSCD 60
           MPWRRRRNRVSALEGGREEEAPPEAAAVPPALLTSPQQTEAAAERILLRGIFEIGRDSCD
Sbjct: 1   MPWRRRRNRVSALEGGREEEAPPEAAAVPPALLTSPQQTEAAAERILLRGIFEIGRDSCD 60

Query: 61  VVLSERALRWRPIQPERPAGDSKYDLLCKEEFIELKDIFSVKLKRRCSVKQQRSGTLLGI 120
           VVLSERALRWRPIQPERPAGDSKYDLLCKEEFIELKDIFSVKLKRRCSVKQQRSGTLLGI
Sbjct: 61  VVLSERALRWRPIQPERPAGDSKYDLLCKEEFIELKDIFSVKLKRRCSVKQQRSGTLLGI 120

Query: 121 TLFICLKKEQNKLKNSTLDLINLSEDHCDIWFRQFKKILAGFPNRPKSLKILLNPQSHKK 180
           TLFICLKKEQNKLKNSTLDLINLSEDHCDIWFRQFKKILAGFPNRPKSLKILLNPQSHKK
Sbjct: 121 TLFICLKKEQNKLKNSTLDLINLSEDHCDIWFRQFKKILAGFPNRPKSLKILLNPQSHKK 180

Query: 181 EATQVYYEKVEPLLKLAGIKTDVTIMEYEGHALSLLKECELQGFDGGHRKPLFAIHWSVQ 240
           EATQVYYEKVEPLLKLAGIKTDVTIMEYEGHALSLLKECELQGFDGGHRKPLFAIHWSVQ
Sbjct: 181 EATQVYYEKVEPLLKLAGIKTDVTIMEYEGHALSLLKECELQGFDGGHRKPLFAIHWSVQ 240

Query: 241 RLFTGMQTLEPSVVCVGGDGSASEVAHALLLRAQKNAGMETDRILTPVRAQLPLGLIPAG 300
           RLFTGMQTLEPSVVCVGGDGSASEVAHALLLRAQKNAGMETDRILTPVRAQLPLGLIPAG
Sbjct: 241 RLFTGMQTLEPSVVCVGGDGSASEVAHALLLRAQKNAGMETDRILTPVRAQLPLGLIPAG 300

Query: 301 STNVLAHSLHGVPHVITATLHIIMGHVQLVDVCTFSTAGKLLRFGFSAMFGFGGRTLALA 360
           STNVLAHSLHGVPHVITATLHIIMGHVQLVDVCTFSTAGKLLRFGFSAMFGFGGRTLALA
Sbjct: 301 STNVLAHSLHGVPHVITATLHIIMGHVQLVDVCTFSTAGKLLRFGFSAMFGFGGRTLALA 360

Query: 361 EKYRWMSPNQRRDFAVVKALAKLKAEDCEISFLPFNSSDDVQERRAQGSPKSDCNDQWQM 420
           EKYRWMSPNQRRDFAVVKALAKLKAEDCEISFLPFNSSDDVQERRAQGSPKSDCNDQWQM
Sbjct: 361 EKYRWMSPNQRRDFAVVKALAKLKAEDCEISFLPFNSSDDVQERRAQGSPKSDCNDQWQM 420

Query: 421 IQGQFLNVSIMAIPCLCSVAPRGLAPNTRLNNGSMALIIARNTSRPEFIKHLKRYASVKN 480
           IQGQFLNVSIMAIPCLCSVAPRGLAPNTRLNNGSMALIIARNTSRPEFIKHLKRYASVKN
Sbjct: 421 IQGQFLNVSIMAIPCLCSVAPRGLAPNTRLNNGSMALIIARNTSRPEFIKHLKRYASVKN 480

Query: 481 QFNFPFVETYTVEEVKVHPRNNTGGYNPEEEEDETASENCFPWNVDGDLMEVASEVHIRL 540
           QFNFPFVETYTVEEVKVHPRNNTGGYNPEEEEDETASENCFPWNVDGDLMEVASEVHIRL
Sbjct: 481 QFNFPFVETYTVEEVKVHPRNNTGGYNPEEEEDETASENCFPWNVDGDLMEVASEVHIRL 540

Query: 541 HPRLISLYGGSMEEMIPK 558
           HPRLISLYGGSMEEMIPK
Sbjct: 541 HPRLISLYGGSMEEMIPK 558


>gi|41680688 ceramide kinase-like isoform a [Homo sapiens]
          Length = 532

 Score = 1057 bits (2734), Expect = 0.0
 Identities = 532/558 (95%), Positives = 532/558 (95%), Gaps = 26/558 (4%)

Query: 1   MPWRRRRNRVSALEGGREEEAPPEAAAVPPALLTSPQQTEAAAERILLRGIFEIGRDSCD 60
           MPWRRRRNRVSALEGGREEEAPPEAAAVPPALLTSPQQTEAAAERILLRGIFEIGRDSCD
Sbjct: 1   MPWRRRRNRVSALEGGREEEAPPEAAAVPPALLTSPQQTEAAAERILLRGIFEIGRDSCD 60

Query: 61  VVLSERALRWRPIQPERPAGDSKYDLLCKEEFIELKDIFSVKLKRRCSVKQQRSGTLLGI 120
           VVLSERALRWRPIQPERPAGDSKYDLLCKEEFIELKDIFSVKLKRRCSVKQQRSGTLLGI
Sbjct: 61  VVLSERALRWRPIQPERPAGDSKYDLLCKEEFIELKDIFSVKLKRRCSVKQQRSGTLLGI 120

Query: 121 TLFICLKKEQNKLKNSTLDLINLSEDHCDIWFRQFKKILAGFPNRPKSLKILLNPQSHKK 180
           TLFICLKKEQNKLKNSTLDLINLSEDHCDIWFRQFKKILAGFPNRPKSLKILLNPQSHKK
Sbjct: 121 TLFICLKKEQNKLKNSTLDLINLSEDHCDIWFRQFKKILAGFPNRPKSLKILLNPQSHKK 180

Query: 181 EATQVYYEKVEPLLKLAGIKTDVTIMEYEGHALSLLKECELQGFDGGHRKPLFAIHWSVQ 240
           EATQVYYEKVEPLLKLAGIKTDVTIMEYEGHALSLLKECELQGFDG              
Sbjct: 181 EATQVYYEKVEPLLKLAGIKTDVTIMEYEGHALSLLKECELQGFDG-------------- 226

Query: 241 RLFTGMQTLEPSVVCVGGDGSASEVAHALLLRAQKNAGMETDRILTPVRAQLPLGLIPAG 300
                       VVCVGGDGSASEVAHALLLRAQKNAGMETDRILTPVRAQLPLGLIPAG
Sbjct: 227 ------------VVCVGGDGSASEVAHALLLRAQKNAGMETDRILTPVRAQLPLGLIPAG 274

Query: 301 STNVLAHSLHGVPHVITATLHIIMGHVQLVDVCTFSTAGKLLRFGFSAMFGFGGRTLALA 360
           STNVLAHSLHGVPHVITATLHIIMGHVQLVDVCTFSTAGKLLRFGFSAMFGFGGRTLALA
Sbjct: 275 STNVLAHSLHGVPHVITATLHIIMGHVQLVDVCTFSTAGKLLRFGFSAMFGFGGRTLALA 334

Query: 361 EKYRWMSPNQRRDFAVVKALAKLKAEDCEISFLPFNSSDDVQERRAQGSPKSDCNDQWQM 420
           EKYRWMSPNQRRDFAVVKALAKLKAEDCEISFLPFNSSDDVQERRAQGSPKSDCNDQWQM
Sbjct: 335 EKYRWMSPNQRRDFAVVKALAKLKAEDCEISFLPFNSSDDVQERRAQGSPKSDCNDQWQM 394

Query: 421 IQGQFLNVSIMAIPCLCSVAPRGLAPNTRLNNGSMALIIARNTSRPEFIKHLKRYASVKN 480
           IQGQFLNVSIMAIPCLCSVAPRGLAPNTRLNNGSMALIIARNTSRPEFIKHLKRYASVKN
Sbjct: 395 IQGQFLNVSIMAIPCLCSVAPRGLAPNTRLNNGSMALIIARNTSRPEFIKHLKRYASVKN 454

Query: 481 QFNFPFVETYTVEEVKVHPRNNTGGYNPEEEEDETASENCFPWNVDGDLMEVASEVHIRL 540
           QFNFPFVETYTVEEVKVHPRNNTGGYNPEEEEDETASENCFPWNVDGDLMEVASEVHIRL
Sbjct: 455 QFNFPFVETYTVEEVKVHPRNNTGGYNPEEEEDETASENCFPWNVDGDLMEVASEVHIRL 514

Query: 541 HPRLISLYGGSMEEMIPK 558
           HPRLISLYGGSMEEMIPK
Sbjct: 515 HPRLISLYGGSMEEMIPK 532


>gi|237757361 ceramide kinase-like isoform g [Homo sapiens]
          Length = 514

 Score = 1018 bits (2631), Expect = 0.0
 Identities = 513/558 (91%), Positives = 514/558 (92%), Gaps = 44/558 (7%)

Query: 1   MPWRRRRNRVSALEGGREEEAPPEAAAVPPALLTSPQQTEAAAERILLRGIFEIGRDSCD 60
           MPWRRRRNRVSALEGGREEEAPPEAAAVPPALLTSPQQTEAAAERILLRGIFEIGRDSCD
Sbjct: 1   MPWRRRRNRVSALEGGREEEAPPEAAAVPPALLTSPQQTEAAAERILLRGIFEIGRDSCD 60

Query: 61  VVLSERALRWRPIQPERPAGDSKYDLLCKEEFIELKDIFSVKLKRRCSVKQQRSGTLLGI 120
           VVLSERALRWRPIQPERPAGDSKYDLLCKEEFIELKDIFSVKLKRRCSVKQQRSGTLLGI
Sbjct: 61  VVLSERALRWRPIQPERPAGDSKYDLLCKEEFIELKDIFSVKLKRRCSVKQQRSGTLLGI 120

Query: 121 TLFICLKKEQNKLKNSTLDLINLSEDHCDIWFRQFKKILAGFPNRPKSLKILLNPQSHKK 180
           TLFICLKKEQNKLKNSTLDLINLSEDHCDIWFRQFKKILA                    
Sbjct: 121 TLFICLKKEQNKLKNSTLDLINLSEDHCDIWFRQFKKILA-------------------- 160

Query: 181 EATQVYYEKVEPLLKLAGIKTDVTIMEYEGHALSLLKECELQGFDGGHRKPLFAIHWSVQ 240
                                   +MEYEGHALSLLKECELQGFDGGHRKPLFAIHWSVQ
Sbjct: 161 ------------------------VMEYEGHALSLLKECELQGFDGGHRKPLFAIHWSVQ 196

Query: 241 RLFTGMQTLEPSVVCVGGDGSASEVAHALLLRAQKNAGMETDRILTPVRAQLPLGLIPAG 300
           RLFTGMQTLEPSVVCVGGDGSASEVAHALLLRAQKNAGMETDRILTPVRAQLPLGLIPAG
Sbjct: 197 RLFTGMQTLEPSVVCVGGDGSASEVAHALLLRAQKNAGMETDRILTPVRAQLPLGLIPAG 256

Query: 301 STNVLAHSLHGVPHVITATLHIIMGHVQLVDVCTFSTAGKLLRFGFSAMFGFGGRTLALA 360
           STNVLAHSLHGVPHVITATLHIIMGHVQLVDVCTFSTAGKLLRFGFSAMFGFGGRTLALA
Sbjct: 257 STNVLAHSLHGVPHVITATLHIIMGHVQLVDVCTFSTAGKLLRFGFSAMFGFGGRTLALA 316

Query: 361 EKYRWMSPNQRRDFAVVKALAKLKAEDCEISFLPFNSSDDVQERRAQGSPKSDCNDQWQM 420
           EKYRWMSPNQRRDFAVVKALAKLKAEDCEISFLPFNSSDDVQERRAQGSPKSDCNDQWQM
Sbjct: 317 EKYRWMSPNQRRDFAVVKALAKLKAEDCEISFLPFNSSDDVQERRAQGSPKSDCNDQWQM 376

Query: 421 IQGQFLNVSIMAIPCLCSVAPRGLAPNTRLNNGSMALIIARNTSRPEFIKHLKRYASVKN 480
           IQGQFLNVSIMAIPCLCSVAPRGLAPNTRLNNGSMALIIARNTSRPEFIKHLKRYASVKN
Sbjct: 377 IQGQFLNVSIMAIPCLCSVAPRGLAPNTRLNNGSMALIIARNTSRPEFIKHLKRYASVKN 436

Query: 481 QFNFPFVETYTVEEVKVHPRNNTGGYNPEEEEDETASENCFPWNVDGDLMEVASEVHIRL 540
           QFNFPFVETYTVEEVKVHPRNNTGGYNPEEEEDETASENCFPWNVDGDLMEVASEVHIRL
Sbjct: 437 QFNFPFVETYTVEEVKVHPRNNTGGYNPEEEEDETASENCFPWNVDGDLMEVASEVHIRL 496

Query: 541 HPRLISLYGGSMEEMIPK 558
           HPRLISLYGGSMEEMIPK
Sbjct: 497 HPRLISLYGGSMEEMIPK 514


>gi|71896725 ceramide kinase-like isoform c [Homo sapiens]
          Length = 419

 Score =  533 bits (1373), Expect = e-151
 Identities = 261/262 (99%), Positives = 261/262 (99%)

Query: 297 IPAGSTNVLAHSLHGVPHVITATLHIIMGHVQLVDVCTFSTAGKLLRFGFSAMFGFGGRT 356
           I AGSTNVLAHSLHGVPHVITATLHIIMGHVQLVDVCTFSTAGKLLRFGFSAMFGFGGRT
Sbjct: 158 ILAGSTNVLAHSLHGVPHVITATLHIIMGHVQLVDVCTFSTAGKLLRFGFSAMFGFGGRT 217

Query: 357 LALAEKYRWMSPNQRRDFAVVKALAKLKAEDCEISFLPFNSSDDVQERRAQGSPKSDCND 416
           LALAEKYRWMSPNQRRDFAVVKALAKLKAEDCEISFLPFNSSDDVQERRAQGSPKSDCND
Sbjct: 218 LALAEKYRWMSPNQRRDFAVVKALAKLKAEDCEISFLPFNSSDDVQERRAQGSPKSDCND 277

Query: 417 QWQMIQGQFLNVSIMAIPCLCSVAPRGLAPNTRLNNGSMALIIARNTSRPEFIKHLKRYA 476
           QWQMIQGQFLNVSIMAIPCLCSVAPRGLAPNTRLNNGSMALIIARNTSRPEFIKHLKRYA
Sbjct: 278 QWQMIQGQFLNVSIMAIPCLCSVAPRGLAPNTRLNNGSMALIIARNTSRPEFIKHLKRYA 337

Query: 477 SVKNQFNFPFVETYTVEEVKVHPRNNTGGYNPEEEEDETASENCFPWNVDGDLMEVASEV 536
           SVKNQFNFPFVETYTVEEVKVHPRNNTGGYNPEEEEDETASENCFPWNVDGDLMEVASEV
Sbjct: 338 SVKNQFNFPFVETYTVEEVKVHPRNNTGGYNPEEEEDETASENCFPWNVDGDLMEVASEV 397

Query: 537 HIRLHPRLISLYGGSMEEMIPK 558
           HIRLHPRLISLYGGSMEEMIPK
Sbjct: 398 HIRLHPRLISLYGGSMEEMIPK 419



 Score =  326 bits (836), Expect = 3e-89
 Identities = 162/164 (98%), Positives = 162/164 (98%)

Query: 1   MPWRRRRNRVSALEGGREEEAPPEAAAVPPALLTSPQQTEAAAERILLRGIFEIGRDSCD 60
           MPWRRRRNRVSALEGGREEEAPPEAAAVPPALLTSPQQTEAAAERILLRGIFEIGRDSCD
Sbjct: 1   MPWRRRRNRVSALEGGREEEAPPEAAAVPPALLTSPQQTEAAAERILLRGIFEIGRDSCD 60

Query: 61  VVLSERALRWRPIQPERPAGDSKYDLLCKEEFIELKDIFSVKLKRRCSVKQQRSGTLLGI 120
           VVLSERALRWRPIQPERPAGDSKYDLLCKEEFIELKDIFSVKLKRRCSVKQQRSGTLLGI
Sbjct: 61  VVLSERALRWRPIQPERPAGDSKYDLLCKEEFIELKDIFSVKLKRRCSVKQQRSGTLLGI 120

Query: 121 TLFICLKKEQNKLKNSTLDLINLSEDHCDIWFRQFKKILAGFPN 164
           TLFICLKKEQNKLKNSTLDLINLSEDHCDIWFRQFKKILAG  N
Sbjct: 121 TLFICLKKEQNKLKNSTLDLINLSEDHCDIWFRQFKKILAGSTN 164


>gi|71896711 ceramide kinase-like isoform d [Homo sapiens]
          Length = 463

 Score =  529 bits (1362), Expect = e-150
 Identities = 258/258 (100%), Positives = 258/258 (100%)

Query: 301 STNVLAHSLHGVPHVITATLHIIMGHVQLVDVCTFSTAGKLLRFGFSAMFGFGGRTLALA 360
           STNVLAHSLHGVPHVITATLHIIMGHVQLVDVCTFSTAGKLLRFGFSAMFGFGGRTLALA
Sbjct: 206 STNVLAHSLHGVPHVITATLHIIMGHVQLVDVCTFSTAGKLLRFGFSAMFGFGGRTLALA 265

Query: 361 EKYRWMSPNQRRDFAVVKALAKLKAEDCEISFLPFNSSDDVQERRAQGSPKSDCNDQWQM 420
           EKYRWMSPNQRRDFAVVKALAKLKAEDCEISFLPFNSSDDVQERRAQGSPKSDCNDQWQM
Sbjct: 266 EKYRWMSPNQRRDFAVVKALAKLKAEDCEISFLPFNSSDDVQERRAQGSPKSDCNDQWQM 325

Query: 421 IQGQFLNVSIMAIPCLCSVAPRGLAPNTRLNNGSMALIIARNTSRPEFIKHLKRYASVKN 480
           IQGQFLNVSIMAIPCLCSVAPRGLAPNTRLNNGSMALIIARNTSRPEFIKHLKRYASVKN
Sbjct: 326 IQGQFLNVSIMAIPCLCSVAPRGLAPNTRLNNGSMALIIARNTSRPEFIKHLKRYASVKN 385

Query: 481 QFNFPFVETYTVEEVKVHPRNNTGGYNPEEEEDETASENCFPWNVDGDLMEVASEVHIRL 540
           QFNFPFVETYTVEEVKVHPRNNTGGYNPEEEEDETASENCFPWNVDGDLMEVASEVHIRL
Sbjct: 386 QFNFPFVETYTVEEVKVHPRNNTGGYNPEEEEDETASENCFPWNVDGDLMEVASEVHIRL 445

Query: 541 HPRLISLYGGSMEEMIPK 558
           HPRLISLYGGSMEEMIPK
Sbjct: 446 HPRLISLYGGSMEEMIPK 463



 Score =  410 bits (1053), Expect = e-114
 Identities = 204/204 (100%), Positives = 204/204 (100%)

Query: 1   MPWRRRRNRVSALEGGREEEAPPEAAAVPPALLTSPQQTEAAAERILLRGIFEIGRDSCD 60
           MPWRRRRNRVSALEGGREEEAPPEAAAVPPALLTSPQQTEAAAERILLRGIFEIGRDSCD
Sbjct: 1   MPWRRRRNRVSALEGGREEEAPPEAAAVPPALLTSPQQTEAAAERILLRGIFEIGRDSCD 60

Query: 61  VVLSERALRWRPIQPERPAGDSKYDLLCKEEFIELKDIFSVKLKRRCSVKQQRSGTLLGI 120
           VVLSERALRWRPIQPERPAGDSKYDLLCKEEFIELKDIFSVKLKRRCSVKQQRSGTLLGI
Sbjct: 61  VVLSERALRWRPIQPERPAGDSKYDLLCKEEFIELKDIFSVKLKRRCSVKQQRSGTLLGI 120

Query: 121 TLFICLKKEQNKLKNSTLDLINLSEDHCDIWFRQFKKILAGFPNRPKSLKILLNPQSHKK 180
           TLFICLKKEQNKLKNSTLDLINLSEDHCDIWFRQFKKILAGFPNRPKSLKILLNPQSHKK
Sbjct: 121 TLFICLKKEQNKLKNSTLDLINLSEDHCDIWFRQFKKILAGFPNRPKSLKILLNPQSHKK 180

Query: 181 EATQVYYEKVEPLLKLAGIKTDVT 204
           EATQVYYEKVEPLLKLAGIKTDVT
Sbjct: 181 EATQVYYEKVEPLLKLAGIKTDVT 204


>gi|20336726 ceramide kinase [Homo sapiens]
          Length = 537

 Score =  195 bits (495), Expect = 1e-49
 Identities = 149/558 (26%), Positives = 256/558 (45%), Gaps = 89/558 (15%)

Query: 48  LRGIFEIGRDSCDVVLSE-RALR--WRPIQPERPAGDSKYDLLCKEEFIELKDIFSVKLK 104
           L+ +  + +  C V L   RAL   WR   P   A  +    +   E I +++   V  K
Sbjct: 10  LQSVLWVKQQRCAVSLEPARALLRWWRSPGPGAGAPGADACSVPVSEIIAVEET-DVHGK 68

Query: 105 RRCSVKQQRSGTLLGITLFICLKKEQNKLKNSTLDLINLSEDHCDIWFRQFKKILAGFPN 164
            + S K Q+       T+    +  +++ K + +      E  C +W +  +++L    +
Sbjct: 69  HQGSGKWQKMEKPYAFTVHCVKRARRHRWKWAQVTFWCPEEQLCHLWLQTLREMLEKLTS 128

Query: 165 RPKSLKILLNPQSHKKEATQVYYEKVEPLLKLAGIKTDVTIMEYEGHALSLLKECELQGF 224
           RPK L + +NP   K +  ++Y  KV PL  LA I TD+ + E+   A   L E  +  +
Sbjct: 129 RPKHLLVFINPFGGKGQGKRIYERKVAPLFTLASITTDIIVTEHANQAKETLYEINIDKY 188

Query: 225 DGGHRKPLFAIHWSVQRLFTGMQTLEPSVVCVGGDGSASEVAHALLLRAQKNAGMETDR- 283
           DG                          +VCVGGDG  SEV H L+ R Q++AG++ +  
Sbjct: 189 DG--------------------------IVCVGGDGMFSEVLHGLIGRTQRSAGVDQNHP 222

Query: 284 --ILTPVRAQLPLGLIPAGSTNVLAHSLHGVPHVITATLHIIMGHVQLVDVCTFSTAGKL 341
             +L P  + L +G+IPAGST+ + +S  G     T+ LHI++G    +DV +      L
Sbjct: 223 RAVLVP--SSLRIGIIPAGSTDCVCYSTVGTSDAETSALHIVVGDSLAMDVSSVHHNSTL 280

Query: 342 LRFGFSAM-FGFGGRTLALAEKYRWMSPNQRRDFAVVKALAKLKAEDCEISFLPFNSS-- 398
           LR+  S + +GF G  +  +EK RW+    R DF+ +K        +  +SFLP   +  
Sbjct: 281 LRYSVSLLGYGFYGDIIKDSEKKRWLGL-ARYDFSGLKTFLSHHCYEGTVSFLPAQHTVG 339

Query: 399 ----------------------DDVQERRAQGSPKSDCNDQWQMIQGQFLNVSIMAIPCL 436
                                 ++ Q++   G   ++  ++WQ++ G+FL ++   + C 
Sbjct: 340 SPRDRKPCRAGCFVCRQSKQQLEEEQKKALYGLEAAEDVEEWQVVCGKFLAINATNMSCA 399

Query: 437 CSVAPRGLAPNTRLNNGSMALIIARNTSRPEFIKHLKRYASVKNQFNFPFVETYTVEEVK 496
           C  +PRGL+P   L +GS  LI+ R  SR  F++ L R+ + ++QF+F FVE Y V++ +
Sbjct: 400 CRRSPRGLSPAAHLGDGSSDLILIRKCSRFNFLRFLIRHTNQQDQFDFTFVEVYRVKKFQ 459

Query: 497 VHPRNNTGGYNPEEEEDETASE--------------NC------FPWNVDGDLMEVASEV 536
              ++        E+ED    E              +C        WN DG+++  +  +
Sbjct: 460 FTSKH-------MEDEDSDLKEGGKKRFGHICSSHPSCCCTVSNSSWNCDGEVLH-SPAI 511

Query: 537 HIRLHPRLISLYGGSMEE 554
            +R+H +L+ L+   +EE
Sbjct: 512 EVRVHCQLVRLFARGIEE 529


>gi|8922701 acylglycerol kinase [Homo sapiens]
          Length = 422

 Score = 57.0 bits (136), Expect = 4e-08
 Identities = 43/171 (25%), Positives = 71/171 (41%), Gaps = 44/171 (25%)

Query: 167 KSLKILLNPQSHKKEATQVYYEKVEPLLKLAGIKTDVTIMEYEGHALSLLKECELQGFDG 226
           K   + LNP + K +A  ++ +   P+L L+G+   +   +YEG A  LL+  E      
Sbjct: 61  KKATVFLNPAACKGKARTLFEKNAAPILHLSGMDVTIVKTDYEGQAKKLLELMENTDV-- 118

Query: 227 GHRKPLFAIHWSVQRLFTGMQTLEPSVVCVGGDGSASEVAHALLLRAQKNAGMETDRILT 286
                                     ++  GGDG+  EV   +L R  +           
Sbjct: 119 --------------------------IIVAGGDGTLQEVVTGVLRRTDE----------- 141

Query: 287 PVRAQLPLGLIPAGSTNVLAHSL-----HGVPHVITATLHIIMGHVQLVDV 332
              +++P+G IP G T+ L+H+L     + V H+  ATL I+ G    +DV
Sbjct: 142 ATFSKIPIGFIPLGETSSLSHTLFAESGNKVQHITDATLAIVKGETVPLDV 192


>gi|217272885 sphingosine kinase 1 isoform 3 [Homo sapiens]
          Length = 384

 Score = 53.9 bits (128), Expect = 4e-07
 Identities = 63/240 (26%), Positives = 96/240 (40%), Gaps = 48/240 (20%)

Query: 165 RPKSLKILLNPQSHKKEATQVYYEKVEPLLKLAGIKTDVTIMEYEGHALSLLKECELQGF 224
           RP  + +LLNP+  K +A Q++   V+PLL  A I   + + E   HA  L++  EL  +
Sbjct: 13  RPCRVLVLLNPRGGKGKALQLFRSHVQPLLAEAEISFTLMLTERRNHARELVRSEELGRW 72

Query: 225 DGGHRKPLFAIHWSVQRLFTGMQTLEPSVVCVGGDGSASEVAHALLLRAQKNAGMETDRI 284
           D                          ++V + GDG   EV + L+ R      +     
Sbjct: 73  D--------------------------ALVVMSGDGLMHEVVNGLMERPDWETAI----- 101

Query: 285 LTPVRAQLPLGLIPAGSTNVLAHSLH---GVPHV------ITATLHIIMGHVQLVDVCTF 335
                 Q PL  +PAGS N LA SL+   G   V         TL +    +  +++ + 
Sbjct: 102 ------QKPLCSLPAGSGNALAASLNHYAGYEQVTNEDLLTNCTLLLCRRLLSPMNLLSL 155

Query: 336 STAGKLLRFG-FSAMFGFGGRTLALAEKYRWMSPNQRRDFAVVKALAKLKAEDCEISFLP 394
            TA  L  F   S  +GF       +EKYR +    R        LA L+     +++LP
Sbjct: 156 HTASGLRLFSVLSLAWGFIADVDLESEKYRRLG-EMRFTLGTFLRLAALRTYRGRLAYLP 214


>gi|217272883 sphingosine kinase 1 isoform 3 [Homo sapiens]
          Length = 384

 Score = 53.9 bits (128), Expect = 4e-07
 Identities = 63/240 (26%), Positives = 96/240 (40%), Gaps = 48/240 (20%)

Query: 165 RPKSLKILLNPQSHKKEATQVYYEKVEPLLKLAGIKTDVTIMEYEGHALSLLKECELQGF 224
           RP  + +LLNP+  K +A Q++   V+PLL  A I   + + E   HA  L++  EL  +
Sbjct: 13  RPCRVLVLLNPRGGKGKALQLFRSHVQPLLAEAEISFTLMLTERRNHARELVRSEELGRW 72

Query: 225 DGGHRKPLFAIHWSVQRLFTGMQTLEPSVVCVGGDGSASEVAHALLLRAQKNAGMETDRI 284
           D                          ++V + GDG   EV + L+ R      +     
Sbjct: 73  D--------------------------ALVVMSGDGLMHEVVNGLMERPDWETAI----- 101

Query: 285 LTPVRAQLPLGLIPAGSTNVLAHSLH---GVPHV------ITATLHIIMGHVQLVDVCTF 335
                 Q PL  +PAGS N LA SL+   G   V         TL +    +  +++ + 
Sbjct: 102 ------QKPLCSLPAGSGNALAASLNHYAGYEQVTNEDLLTNCTLLLCRRLLSPMNLLSL 155

Query: 336 STAGKLLRFG-FSAMFGFGGRTLALAEKYRWMSPNQRRDFAVVKALAKLKAEDCEISFLP 394
            TA  L  F   S  +GF       +EKYR +    R        LA L+     +++LP
Sbjct: 156 HTASGLRLFSVLSLAWGFIADVDLESEKYRRLG-EMRFTLGTFLRLAALRTYRGRLAYLP 214


>gi|21361088 sphingosine kinase 1 isoform 1 [Homo sapiens]
          Length = 398

 Score = 53.9 bits (128), Expect = 4e-07
 Identities = 63/240 (26%), Positives = 96/240 (40%), Gaps = 48/240 (20%)

Query: 165 RPKSLKILLNPQSHKKEATQVYYEKVEPLLKLAGIKTDVTIMEYEGHALSLLKECELQGF 224
           RP  + +LLNP+  K +A Q++   V+PLL  A I   + + E   HA  L++  EL  +
Sbjct: 27  RPCRVLVLLNPRGGKGKALQLFRSHVQPLLAEAEISFTLMLTERRNHARELVRSEELGRW 86

Query: 225 DGGHRKPLFAIHWSVQRLFTGMQTLEPSVVCVGGDGSASEVAHALLLRAQKNAGMETDRI 284
           D                          ++V + GDG   EV + L+ R      +     
Sbjct: 87  D--------------------------ALVVMSGDGLMHEVVNGLMERPDWETAI----- 115

Query: 285 LTPVRAQLPLGLIPAGSTNVLAHSLH---GVPHV------ITATLHIIMGHVQLVDVCTF 335
                 Q PL  +PAGS N LA SL+   G   V         TL +    +  +++ + 
Sbjct: 116 ------QKPLCSLPAGSGNALAASLNHYAGYEQVTNEDLLTNCTLLLCRRLLSPMNLLSL 169

Query: 336 STAGKLLRFG-FSAMFGFGGRTLALAEKYRWMSPNQRRDFAVVKALAKLKAEDCEISFLP 394
            TA  L  F   S  +GF       +EKYR +    R        LA L+     +++LP
Sbjct: 170 HTASGLRLFSVLSLAWGFIADVDLESEKYRRLG-EMRFTLGTFLRLAALRTYRGRLAYLP 228


>gi|217272880 sphingosine kinase 1 isoform 2 [Homo sapiens]
          Length = 470

 Score = 53.9 bits (128), Expect = 4e-07
 Identities = 63/240 (26%), Positives = 96/240 (40%), Gaps = 48/240 (20%)

Query: 165 RPKSLKILLNPQSHKKEATQVYYEKVEPLLKLAGIKTDVTIMEYEGHALSLLKECELQGF 224
           RP  + +LLNP+  K +A Q++   V+PLL  A I   + + E   HA  L++  EL  +
Sbjct: 99  RPCRVLVLLNPRGGKGKALQLFRSHVQPLLAEAEISFTLMLTERRNHARELVRSEELGRW 158

Query: 225 DGGHRKPLFAIHWSVQRLFTGMQTLEPSVVCVGGDGSASEVAHALLLRAQKNAGMETDRI 284
           D                          ++V + GDG   EV + L+ R      +     
Sbjct: 159 D--------------------------ALVVMSGDGLMHEVVNGLMERPDWETAI----- 187

Query: 285 LTPVRAQLPLGLIPAGSTNVLAHSLH---GVPHV------ITATLHIIMGHVQLVDVCTF 335
                 Q PL  +PAGS N LA SL+   G   V         TL +    +  +++ + 
Sbjct: 188 ------QKPLCSLPAGSGNALAASLNHYAGYEQVTNEDLLTNCTLLLCRRLLSPMNLLSL 241

Query: 336 STAGKLLRFG-FSAMFGFGGRTLALAEKYRWMSPNQRRDFAVVKALAKLKAEDCEISFLP 394
            TA  L  F   S  +GF       +EKYR +    R        LA L+     +++LP
Sbjct: 242 HTASGLRLFSVLSLAWGFIADVDLESEKYRRLG-EMRFTLGTFLRLAALRTYRGRLAYLP 300


>gi|21361699 sphingosine kinase 2 [Homo sapiens]
          Length = 654

 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 58/240 (24%), Positives = 97/240 (40%), Gaps = 48/240 (20%)

Query: 165 RPKSLKILLNPQSHKKEATQVYYEKVEPLLKLAGIKTDVTIMEYEGHALSLLKECELQGF 224
           RP  L +L+NP   +  A Q     V P++  AG+  ++   E + HA  L++   L  +
Sbjct: 179 RPPRLLLLVNPFGGRGLAWQWCKNHVLPMISEAGLSFNLIQTERQNHARELVQGLSLSEW 238

Query: 225 DGGHRKPLFAIHWSVQRLFTGMQTLEPSVVCVGGDGSASEVAHALLLRAQKNAGMETDRI 284
           DG                          +V V GDG   EV + LL           DR 
Sbjct: 239 DG--------------------------IVTVSGDGLLHEVLNGLL-----------DRP 261

Query: 285 LTPVRAQLPLGLIPAGSTNVLAHSLH---------GVPHVITATLHIIMGHVQLVDVCTF 335
                 ++P+G++P GS N LA +++         G+  ++  +L +  G    +D+ + 
Sbjct: 262 DWEEAVKMPVGILPCGSGNALAGAVNQHGGFEPALGLDLLLNCSLLLCRGGGHPLDLLSV 321

Query: 336 STAGKLLRFGF-SAMFGFGGRTLALAEKYRWMSPNQRRDFAVVKALAKLKAEDCEISFLP 394
           + A     F F S  +GF       +E++R +  + R     V  LA L      +S+LP
Sbjct: 322 TLASGSRCFSFLSVAWGFVSDVDIQSERFRALG-SARFTLGTVLGLATLHTYRGRLSYLP 380


>gi|48255900 SWI/SNF-related matrix-associated actin-dependent
           regulator of chromatin a2 isoform a [Homo sapiens]
          Length = 1590

 Score = 33.5 bits (75), Expect = 0.53
 Identities = 43/174 (24%), Positives = 69/174 (39%), Gaps = 32/174 (18%)

Query: 15  GGREEEAPPEAAAVPPALLTSPQQTEAAAERILLRGIFEIGRDSCDVVLSERALRWRPIQ 74
           GGR   APP AA  P A +  P   + A            G+ S  + L ++  R  PIQ
Sbjct: 284 GGRPSPAPPAAAQPPAAAVPGPSVPQPAP-----------GQPSPVLQLQQKQSRISPIQ 332

Query: 75  PERPAGDSKYDLLCKEEFIELKDIFSVKLKRRCSVKQQRSGTLLGITLFICLKKEQNKLK 134
             +P G    ++L + E+         +L+ R + + Q    L G        K   +LK
Sbjct: 333 --KPQGLDPVEILQEREY---------RLQARIAHRIQELENLPGSLPPDLRTKATVELK 381

Query: 135 NSTLDLINLSEDHCDIWFRQFKKILAGFPNRPKSLKILLNPQSHKKEATQVYYE 188
              L L+N          RQ ++ +     R  +L+  LN +++K+   Q   E
Sbjct: 382 --ALRLLNFQ--------RQLRQEVVACMRRDTTLETALNSKAYKRSKRQTLRE 425


>gi|48255898 SWI/SNF-related matrix-associated actin-dependent
           regulator of chromatin a2 isoform b [Homo sapiens]
          Length = 1572

 Score = 33.5 bits (75), Expect = 0.53
 Identities = 43/174 (24%), Positives = 69/174 (39%), Gaps = 32/174 (18%)

Query: 15  GGREEEAPPEAAAVPPALLTSPQQTEAAAERILLRGIFEIGRDSCDVVLSERALRWRPIQ 74
           GGR   APP AA  P A +  P   + A            G+ S  + L ++  R  PIQ
Sbjct: 284 GGRPSPAPPAAAQPPAAAVPGPSVPQPAP-----------GQPSPVLQLQQKQSRISPIQ 332

Query: 75  PERPAGDSKYDLLCKEEFIELKDIFSVKLKRRCSVKQQRSGTLLGITLFICLKKEQNKLK 134
             +P G    ++L + E+         +L+ R + + Q    L G        K   +LK
Sbjct: 333 --KPQGLDPVEILQEREY---------RLQARIAHRIQELENLPGSLPPDLRTKATVELK 381

Query: 135 NSTLDLINLSEDHCDIWFRQFKKILAGFPNRPKSLKILLNPQSHKKEATQVYYE 188
              L L+N          RQ ++ +     R  +L+  LN +++K+   Q   E
Sbjct: 382 --ALRLLNFQ--------RQLRQEVVACMRRDTTLETALNSKAYKRSKRQTLRE 425


>gi|39930469 brix domain containing 1 [Homo sapiens]
          Length = 306

 Score = 31.6 bits (70), Expect = 2.0
 Identities = 29/106 (27%), Positives = 48/106 (45%), Gaps = 7/106 (6%)

Query: 118 LGITLFICLKKEQN-KLKNSTLDLINLSEDHCDIW--FRQFKKILAGFPNRPKSLKILLN 174
           LGI  F+ LK  +N K    T  ++  + D  D+   +R+ K +L  F   P    I L 
Sbjct: 119 LGIENFVSLKDIKNSKCPEGTKPMLIFAGDDFDVTEDYRRLKSLLIDFFRGPTVSNIRLA 178

Query: 175 PQSHKKEAT----QVYYEKVEPLLKLAGIKTDVTIMEYEGHALSLL 216
              +    T    ++Y+   + LLK +G +T    +E  G +L L+
Sbjct: 179 GLEYVLHFTALNGKIYFRSYKLLLKKSGCRTPRIELEEMGPSLDLV 224


>gi|4502897 cleft lip and palate associated transmembrane protein 1
           [Homo sapiens]
          Length = 669

 Score = 31.6 bits (70), Expect = 2.0
 Identities = 22/84 (26%), Positives = 34/84 (40%), Gaps = 2/84 (2%)

Query: 399 DDVQERRAQGSPKSDCNDQWQMIQGQFLNVSIMAIPCLCSVAPRGLAPNTRLNNGSMALI 458
           D   E + Q  P     + WQ+I+G    + I  I  + S   RG AP  +   G    +
Sbjct: 34  DPPAETQPQNPPAQPAPNAWQVIKGVLFRIFI--IWAISSWFRRGPAPQDQAGPGGAPRV 91

Query: 459 IARNTSRPEFIKHLKRYASVKNQF 482
            +RN    + + +L  Y S    F
Sbjct: 92  ASRNLFPKDTLMNLHVYISEHEHF 115


>gi|157694487 CMT1A duplicated region transcript 1 [Homo sapiens]
          Length = 752

 Score = 30.8 bits (68), Expect = 3.4
 Identities = 30/107 (28%), Positives = 49/107 (45%), Gaps = 13/107 (12%)

Query: 208 YEGHALSLLK-----ECELQGFDGGHRKPLFAIHWSVQRLFTGMQTLEPSVVCVGGDGSA 262
           + G+ + ++K     +  L  F  G+R  +  I    +R+  G   +EPS    GG+ S 
Sbjct: 643 FNGNCMKVIKANGRGDPVLSFFIQGNRISVCHISTFAKRINVGWNGIEPSATAQGGNASL 702

Query: 263 SEVAHALLLRAQKNAGMETDRILTPVRAQLPL--GLIP-AGSTNVLA 306
           +E AH   +R      +   R+  PV A  P+  G+ P    T+VLA
Sbjct: 703 TECAH---VRLHIAGHLPASRL--PVAAVQPMTGGMAPTTAPTHVLA 744


>gi|51093832 GTPase activating protein and VPS9 domains 1 [Homo
            sapiens]
          Length = 1487

 Score = 30.4 bits (67), Expect = 4.5
 Identities = 20/69 (28%), Positives = 28/69 (40%), Gaps = 7/69 (10%)

Query: 3    WRRRRNRVSALEGGREEEAPPEAAAVPPALLTSPQQTEAAAERILLRGIFEIGRDSCDVV 62
            W RR        G  E E PP AA    +L+ +P  + ++  +   RG  E  +DS D  
Sbjct: 945  WNRR-------PGNEERELPPAAAIGATSLVAAPHSSSSSPSKDSSRGETEERKDSDDEK 997

Query: 63   LSERALRWR 71
                   WR
Sbjct: 998  SDRNRPWWR 1006


>gi|33356148 formin-like 1 [Homo sapiens]
          Length = 1100

 Score = 30.4 bits (67), Expect = 4.5
 Identities = 21/74 (28%), Positives = 28/74 (37%), Gaps = 4/74 (5%)

Query: 7   RNRVSALEGGREEEAPPEAAAVPPALLTSPQQTEAAAERILLRGIFEIGRDSCDVVLSER 66
           R R S          PPE    PPA  T P   E   E +  +G+  I R   D V    
Sbjct: 444 RERFSESTAMGASRRPPEPEKAPPAAPTRPSALELKVEELEEKGLIRILRGPGDAV---- 499

Query: 67  ALRWRPIQPERPAG 80
           ++   P+    P+G
Sbjct: 500 SIEILPVAVATPSG 513


>gi|7661950 SH2 domain binding protein 1 [Homo sapiens]
          Length = 1173

 Score = 30.0 bits (66), Expect = 5.8
 Identities = 23/80 (28%), Positives = 41/80 (51%), Gaps = 16/80 (20%)

Query: 155 FKKILAGFPNRPKSLKILLN-------------PQSHKKEATQVYYEKVEPLLKLAGI-- 199
           F+K+L  +PN  +++KIL +              + H K+ T+ Y + VE  ++LA I  
Sbjct: 364 FEKVLKAYPNNYETMKILGSLYAASEDQEKRDIAKGHLKKVTEQYPDDVEAWIELAQILE 423

Query: 200 KTDVT-IMEYEGHALSLLKE 218
           +TD+   +   G A  +L+E
Sbjct: 424 QTDIQGALSAYGTATRILQE 443


>gi|239753057 PREDICTED: hypothetical protein XP_002345334 [Homo
           sapiens]
          Length = 212

 Score = 29.3 bits (64), Expect = 10.0
 Identities = 28/139 (20%), Positives = 56/139 (40%), Gaps = 10/139 (7%)

Query: 198 GIKTDVTIMEYEGHALSLLKECELQGFDGGHRKPLFAIHWSVQRLFTGMQTLEPSVVCVG 257
           G+++ V + ++    ++  K  +++  DG  R+      W  + +      L P V    
Sbjct: 9   GLRSRVVVEDFSPDPVTGQKHTQVKSLDGYTRRLWLEPPWHERTIRGTAALLHPHV---- 64

Query: 258 GDGSASEVAHALLLRAQ---KNAGMETDRILTPVRAQLP---LGLIPAGSTNVLAHSLHG 311
           G         A LL A    +   +  D +  P +  L    L  +PAG+  +++    G
Sbjct: 65  GQADHLGPGPASLLDADDHGQRVSLRGDALSRPQKRPLEGQGLRGLPAGAHTLISQEARG 124

Query: 312 VPHVITATLHIIMGHVQLV 330
           + H +   LH +  +V L+
Sbjct: 125 LQHPVLGPLHPLQVNVHLL 143


>gi|239747608 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 212

 Score = 29.3 bits (64), Expect = 10.0
 Identities = 28/139 (20%), Positives = 56/139 (40%), Gaps = 10/139 (7%)

Query: 198 GIKTDVTIMEYEGHALSLLKECELQGFDGGHRKPLFAIHWSVQRLFTGMQTLEPSVVCVG 257
           G+++ V + ++    ++  K  +++  DG  R+      W  + +      L P V    
Sbjct: 9   GLRSRVVVEDFSPDPVTGQKHTQVKSLDGYTRRLWLEPPWHERTIRGTAALLHPHV---- 64

Query: 258 GDGSASEVAHALLLRAQ---KNAGMETDRILTPVRAQLP---LGLIPAGSTNVLAHSLHG 311
           G         A LL A    +   +  D +  P +  L    L  +PAG+  +++    G
Sbjct: 65  GQADHLGPGPASLLDADDHGQRVSLRGDALSRPQKRPLEGQGLRGLPAGAHTLISQEARG 124

Query: 312 VPHVITATLHIIMGHVQLV 330
           + H +   LH +  +V L+
Sbjct: 125 LQHPVLGPLHPLQVNVHLL 143


>gi|239741483 PREDICTED: hypothetical protein XP_002342212 [Homo
           sapiens]
          Length = 212

 Score = 29.3 bits (64), Expect = 10.0
 Identities = 28/139 (20%), Positives = 56/139 (40%), Gaps = 10/139 (7%)

Query: 198 GIKTDVTIMEYEGHALSLLKECELQGFDGGHRKPLFAIHWSVQRLFTGMQTLEPSVVCVG 257
           G+++ V + ++    ++  K  +++  DG  R+      W  + +      L P V    
Sbjct: 9   GLRSRVVVEDFSPDPVTGQKHTQVKSLDGYTRRLWLEPPWHERTIRGTAALLHPHV---- 64

Query: 258 GDGSASEVAHALLLRAQ---KNAGMETDRILTPVRAQLP---LGLIPAGSTNVLAHSLHG 311
           G         A LL A    +   +  D +  P +  L    L  +PAG+  +++    G
Sbjct: 65  GQADHLGPGPASLLDADDHGQRVSLRGDALSRPQKRPLEGQGLRGLPAGAHTLISQEARG 124

Query: 312 VPHVITATLHIIMGHVQLV 330
           + H +   LH +  +V L+
Sbjct: 125 LQHPVLGPLHPLQVNVHLL 143


>gi|33598960 alpha-2B-adrenergic receptor [Homo sapiens]
          Length = 450

 Score = 29.3 bits (64), Expect = 10.0
 Identities = 18/45 (40%), Positives = 22/45 (48%), Gaps = 2/45 (4%)

Query: 14  EGGREEEAPPEAAAVPPALLTSPQQTEAAAERIL--LRGIFEIGR 56
           E   EEE  P+A  V PA   SP   +    R+L  LRG   +GR
Sbjct: 303 EEEEEEECEPQAVPVSPASACSPPLQQPQGSRVLATLRGQVLLGR 347


>gi|62243658 PI-3-kinase-related kinase SMG-1 [Homo sapiens]
          Length = 3661

 Score = 29.3 bits (64), Expect = 10.0
 Identities = 11/36 (30%), Positives = 21/36 (58%)

Query: 183  TQVYYEKVEPLLKLAGIKTDVTIMEYEGHALSLLKE 218
            +++YY K+ P LK  G+  DV+  ++  H +  + E
Sbjct: 2250 SELYYSKIGPALKTVGLSLDVSRRDWPLHVMKAVLE 2285


>gi|11055976 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase
           6 [Homo sapiens]
          Length = 395

 Score = 29.3 bits (64), Expect = 10.0
 Identities = 20/69 (28%), Positives = 32/69 (46%), Gaps = 8/69 (11%)

Query: 1   MPWRRRRNRVSALEGGREEEAPPEAAAVPPALLTSPQQTEAAAERILLRGIFEIGRDSC- 59
           +PWRR  + +      R   +PP  +A P   ++S    EA  + +  R  F + R++C 
Sbjct: 111 LPWRRNLSDLFQWAVSRALCSPPACSAFPRGAISS----EAVCKPLCARQSFTLAREACR 166

Query: 60  ---DVVLSE 65
               VVL E
Sbjct: 167 SYSHVVLKE 175


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.136    0.408 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,854,483
Number of Sequences: 37866
Number of extensions: 996600
Number of successful extensions: 2817
Number of sequences better than 10.0: 26
Number of HSP's better than 10.0 without gapping: 16
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 2785
Number of HSP's gapped (non-prelim): 33
length of query: 558
length of database: 18,247,518
effective HSP length: 107
effective length of query: 451
effective length of database: 14,195,856
effective search space: 6402331056
effective search space used: 6402331056
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.