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Search of human proteins with 71274140
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|71274140 profilin 3 [Homo sapiens]
(137 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|71274140 profilin 3 [Homo sapiens] 279 6e-76
gi|4826898 profilin 1 [Homo sapiens] 117 2e-27
gi|4505751 profilin 2 isoform b [Homo sapiens] 116 7e-27
gi|16753215 profilin 2 isoform a [Homo sapiens] 112 1e-25
gi|239741295 PREDICTED: similar to PDE4DIP protein [Homo sapiens] 42 2e-04
gi|24308065 netrin 5 [Homo sapiens] 35 0.025
gi|113429326 PREDICTED: gamma-glutamyltransferase 2 isoform 1 [H... 30 0.62
gi|73915096 gamma-glutamyltransferase 1 precursor [Homo sapiens] 29 1.1
gi|73915094 gamma-glutamyltransferase 1 precursor [Homo sapiens] 29 1.1
gi|73915092 gamma-glutamyltransferase 1 precursor [Homo sapiens] 29 1.1
gi|73915090 gamma-glutamyltransferase 1 precursor [Homo sapiens] 29 1.1
gi|113429324 PREDICTED: gamma-glutamyltransferase 2 isoform 3 [H... 29 1.1
gi|239747656 PREDICTED: similar to mCG116201 [Homo sapiens] 28 1.8
gi|7019549 T-box 21 [Homo sapiens] 28 2.4
gi|58331191 tyrosine kinase, non-receptor, 2 isoform 2 [Homo sap... 28 2.4
gi|239757877 PREDICTED: FERM and PDZ domain containing 3 [Homo s... 27 4.0
gi|89060961 PREDICTED: FERM and PDZ domain containing 3 [Homo sa... 27 4.0
gi|89059963 PREDICTED: FERM and PDZ domain containing 3 [Homo sa... 27 4.0
gi|239751469 PREDICTED: hypothetical protein [Homo sapiens] 26 9.0
gi|14589937 protocadherin 8 isoform 2 precursor [Homo sapiens] 26 9.0
gi|6631102 protocadherin 8 isoform 1 precursor [Homo sapiens] 26 9.0
gi|47578107 delangin isoform B [Homo sapiens] 26 9.0
gi|47578105 delangin isoform A [Homo sapiens] 26 9.0
gi|30089935 transmembrane protein 132A isoform a [Homo sapiens] 26 9.0
gi|30089937 transmembrane protein 132A isoform b [Homo sapiens] 26 9.0
>gi|71274140 profilin 3 [Homo sapiens]
Length = 137
Score = 279 bits (713), Expect = 6e-76
Identities = 137/137 (100%), Positives = 137/137 (100%)
Query: 1 MGDWKVYISAVLRDQRIDDVAIVGHADNSCVWASRPGGLLAAISPQEVGVLTGPDRHTFL 60
MGDWKVYISAVLRDQRIDDVAIVGHADNSCVWASRPGGLLAAISPQEVGVLTGPDRHTFL
Sbjct: 1 MGDWKVYISAVLRDQRIDDVAIVGHADNSCVWASRPGGLLAAISPQEVGVLTGPDRHTFL 60
Query: 61 QAGLSVGGRRCCVIRDHLLAEGDGVLDARTKGLDARAVCVGRAPRALLVLMGRRGVHGGI 120
QAGLSVGGRRCCVIRDHLLAEGDGVLDARTKGLDARAVCVGRAPRALLVLMGRRGVHGGI
Sbjct: 61 QAGLSVGGRRCCVIRDHLLAEGDGVLDARTKGLDARAVCVGRAPRALLVLMGRRGVHGGI 120
Query: 121 LNKTVHELIRGLRMQGA 137
LNKTVHELIRGLRMQGA
Sbjct: 121 LNKTVHELIRGLRMQGA 137
>gi|4826898 profilin 1 [Homo sapiens]
Length = 140
Score = 117 bits (294), Expect = 2e-27
Identities = 60/136 (44%), Positives = 83/136 (61%), Gaps = 3/136 (2%)
Query: 1 MGDWKVYISAVLRDQRIDDVAIVGHADNSCVWASRPGGLLAAISPQEVGVLTGPDRHTFL 60
M W YI ++ D D AIVG+ D+ VWA+ PG I+P EVGVL G DR +F
Sbjct: 1 MAGWNAYIDNLMADGTCQDAAIVGYKDSPSVWAAVPGKTFVNITPAEVGVLVGKDRSSFY 60
Query: 61 QAGLSVGGRRCCVIRDHLLAEGDGVLDARTK---GLDARAVCVGRAPRALLVLMGRRGVH 117
GL++GG++C VIRD LL +G+ +D RTK G V V + + L++LMG+ GVH
Sbjct: 61 VNGLTLGGQKCSVIRDSLLQDGEFSMDLRTKSTGGAPTFNVTVTKTDKTLVLLMGKEGVH 120
Query: 118 GGILNKTVHELIRGLR 133
GG++NK +E+ LR
Sbjct: 121 GGLINKKCYEMASHLR 136
>gi|4505751 profilin 2 isoform b [Homo sapiens]
Length = 140
Score = 116 bits (290), Expect = 7e-27
Identities = 59/136 (43%), Positives = 83/136 (61%), Gaps = 3/136 (2%)
Query: 1 MGDWKVYISAVLRDQRIDDVAIVGHADNSCVWASRPGGLLAAISPQEVGVLTGPDRHTFL 60
M W+ Y+ ++ D + AIVG+ D VWA+ GG+ +I+P E+ ++ G DR F
Sbjct: 1 MAGWQSYVDNLMCDGCCQEAAIVGYCDAKYVWAATAGGVFQSITPIEIDMIVGKDREGFF 60
Query: 61 QAGLSVGGRRCCVIRDHLLAEGDGVLDARTK---GLDARAVCVGRAPRALLVLMGRRGVH 117
GL++G ++C VIRD L +GD +D RTK G V VGRA RAL+++MG+ GVH
Sbjct: 61 TNGLTLGAKKCSVIRDSLYVDGDCTMDIRTKSQGGEPTYNVAVGRAGRALVIVMGKEGVH 120
Query: 118 GGILNKTVHELIRGLR 133
GG LNK +EL LR
Sbjct: 121 GGTLNKKAYELALYLR 136
>gi|16753215 profilin 2 isoform a [Homo sapiens]
Length = 140
Score = 112 bits (279), Expect = 1e-25
Identities = 57/139 (41%), Positives = 82/139 (58%), Gaps = 3/139 (2%)
Query: 1 MGDWKVYISAVLRDQRIDDVAIVGHADNSCVWASRPGGLLAAISPQEVGVLTGPDRHTFL 60
M W+ Y+ ++ D + AIVG+ D VWA+ GG+ +I+P E+ ++ G DR F
Sbjct: 1 MAGWQSYVDNLMCDGCCQEAAIVGYCDAKYVWAATAGGVFQSITPIEIDMIVGKDREGFF 60
Query: 61 QAGLSVGGRRCCVIRDHLLAEGDGVLDARTK---GLDARAVCVGRAPRALLVLMGRRGVH 117
GL++G ++C VIRD L +GD +D RTK G V VGRA R L+ +MG+ GVH
Sbjct: 61 TNGLTLGAKKCSVIRDSLYVDGDCTMDIRTKSQGGEPTYNVAVGRAGRVLVFVMGKEGVH 120
Query: 118 GGILNKTVHELIRGLRMQG 136
GG LNK + + + LR G
Sbjct: 121 GGGLNKKAYSMAKYLRDSG 139
>gi|239741295 PREDICTED: similar to PDE4DIP protein [Homo sapiens]
Length = 66
Score = 42.0 bits (97), Expect = 2e-04
Identities = 22/64 (34%), Positives = 35/64 (54%), Gaps = 3/64 (4%)
Query: 63 GLSVGGRRCCVIRDHLLAEGDGVLDARTKGLDARA---VCVGRAPRALLVLMGRRGVHGG 119
GL++GG++ V+ D LL +G+ D K + V V + L +LMG+ G+HG
Sbjct: 3 GLTLGGQKYTVVLDSLLQDGELTTDLCMKSISGAPTFNVIVTMTAKTLGLLMGKEGIHGN 62
Query: 120 ILNK 123
+NK
Sbjct: 63 FINK 66
>gi|24308065 netrin 5 [Homo sapiens]
Length = 489
Score = 34.7 bits (78), Expect = 0.025
Identities = 27/77 (35%), Positives = 29/77 (37%), Gaps = 4/77 (5%)
Query: 29 SCVWASRPGGLLAAISPQEVGVLTGPDRHTFLQAGLSVGGRRCCVIRDHLLAEGDGVLDA 88
S WAS L P G L GP+R TF S G + V HL E G
Sbjct: 93 SAAWASGGPWRLLWHRPAWPGALGGPERVTFH----STPGPKATVAASHLRVEFGGQAGL 148
Query: 89 RTKGLDARAVCVGRAPR 105
GL R C G A R
Sbjct: 149 AAAGLRGRCQCHGHAAR 165
>gi|113429326 PREDICTED: gamma-glutamyltransferase 2 isoform 1 [Homo
sapiens]
Length = 574
Score = 30.0 bits (66), Expect = 0.62
Identities = 22/78 (28%), Positives = 33/78 (42%), Gaps = 14/78 (17%)
Query: 54 PDRHTFLQAGLSVGGRRCCVIRDHLLAEGDGVLDARTKGLDARAVCVGRAPRALLVLMGR 113
PD H + +A ++ ++C I L +G +DA L +CVG L+
Sbjct: 33 PDNHVYTRAAMAADAKQCLEIGRDTLRDGGSAVDAAIAAL----LCVG------LMNAHS 82
Query: 114 RGVHGG----ILNKTVHE 127
G+ G I N T HE
Sbjct: 83 MGIGVGLFLTIYNSTTHE 100
>gi|73915096 gamma-glutamyltransferase 1 precursor [Homo sapiens]
Length = 569
Score = 29.3 bits (64), Expect = 1.1
Identities = 18/67 (26%), Positives = 30/67 (44%), Gaps = 10/67 (14%)
Query: 54 PDRHTFLQAGLSVGGRRCCVIRDHLLAEGDGVLDARTKGLDARAVCVGRAPRALLVLMGR 113
PD H + +A ++ ++C I L +G +DA L +CVG L+
Sbjct: 33 PDNHVYTRAAVAADAKQCSKIGRDALRDGGSAVDAAIAAL----LCVG------LMNAHS 82
Query: 114 RGVHGGI 120
G+ GG+
Sbjct: 83 MGIGGGL 89
>gi|73915094 gamma-glutamyltransferase 1 precursor [Homo sapiens]
Length = 569
Score = 29.3 bits (64), Expect = 1.1
Identities = 18/67 (26%), Positives = 30/67 (44%), Gaps = 10/67 (14%)
Query: 54 PDRHTFLQAGLSVGGRRCCVIRDHLLAEGDGVLDARTKGLDARAVCVGRAPRALLVLMGR 113
PD H + +A ++ ++C I L +G +DA L +CVG L+
Sbjct: 33 PDNHVYTRAAVAADAKQCSKIGRDALRDGGSAVDAAIAAL----LCVG------LMNAHS 82
Query: 114 RGVHGGI 120
G+ GG+
Sbjct: 83 MGIGGGL 89
>gi|73915092 gamma-glutamyltransferase 1 precursor [Homo sapiens]
Length = 569
Score = 29.3 bits (64), Expect = 1.1
Identities = 18/67 (26%), Positives = 30/67 (44%), Gaps = 10/67 (14%)
Query: 54 PDRHTFLQAGLSVGGRRCCVIRDHLLAEGDGVLDARTKGLDARAVCVGRAPRALLVLMGR 113
PD H + +A ++ ++C I L +G +DA L +CVG L+
Sbjct: 33 PDNHVYTRAAVAADAKQCSKIGRDALRDGGSAVDAAIAAL----LCVG------LMNAHS 82
Query: 114 RGVHGGI 120
G+ GG+
Sbjct: 83 MGIGGGL 89
>gi|73915090 gamma-glutamyltransferase 1 precursor [Homo sapiens]
Length = 569
Score = 29.3 bits (64), Expect = 1.1
Identities = 18/67 (26%), Positives = 30/67 (44%), Gaps = 10/67 (14%)
Query: 54 PDRHTFLQAGLSVGGRRCCVIRDHLLAEGDGVLDARTKGLDARAVCVGRAPRALLVLMGR 113
PD H + +A ++ ++C I L +G +DA L +CVG L+
Sbjct: 33 PDNHVYTRAAVAADAKQCSKIGRDALRDGGSAVDAAIAAL----LCVG------LMNAHS 82
Query: 114 RGVHGGI 120
G+ GG+
Sbjct: 83 MGIGGGL 89
>gi|113429324 PREDICTED: gamma-glutamyltransferase 2 isoform 3 [Homo
sapiens]
Length = 569
Score = 29.3 bits (64), Expect = 1.1
Identities = 14/48 (29%), Positives = 23/48 (47%), Gaps = 4/48 (8%)
Query: 54 PDRHTFLQAGLSVGGRRCCVIRDHLLAEGDGVLDARTKGLDARAVCVG 101
PD H + +A ++ ++C I L +G +DA L +CVG
Sbjct: 33 PDNHVYTRAAMAADAKQCLEIGRDTLRDGGSAVDAAIAAL----LCVG 76
>gi|239747656 PREDICTED: similar to mCG116201 [Homo sapiens]
Length = 591
Score = 28.5 bits (62), Expect = 1.8
Identities = 16/55 (29%), Positives = 25/55 (45%)
Query: 82 GDGVLDARTKGLDARAVCVGRAPRALLVLMGRRGVHGGILNKTVHELIRGLRMQG 136
G G+LD+ +G +A + G+ M G + GI+ EL R + QG
Sbjct: 61 GRGILDSAWQGYNATLLAYGQTGSGKSYSMIGFGANXGIIPTVCEELFRAIENQG 115
>gi|7019549 T-box 21 [Homo sapiens]
Length = 535
Score = 28.1 bits (61), Expect = 2.4
Identities = 17/45 (37%), Positives = 23/45 (51%), Gaps = 1/45 (2%)
Query: 35 RPGGLLAAISPQEVGVLTGPDRHTFLQAGLSVGGRRCCVIRDHLL 79
+PG AA P+ G+ GP L AGL V G+ + +HLL
Sbjct: 103 QPGEGYAAPDPR-AGLYPGPREDYALPAGLEVSGKLRVALNNHLL 146
>gi|58331191 tyrosine kinase, non-receptor, 2 isoform 2 [Homo
sapiens]
Length = 1086
Score = 28.1 bits (61), Expect = 2.4
Identities = 15/44 (34%), Positives = 24/44 (54%), Gaps = 1/44 (2%)
Query: 89 RTKGLDARAVCVGRAPRALLV-LMGRRGVHGGILNKTVHELIRG 131
RT+G DA GR RALL+ L G+ G + ++ ++ + G
Sbjct: 8 RTQGSDAAGAAAGRGLRALLLSLTAAAGIWGSMGERSAYQRLAG 51
>gi|239757877 PREDICTED: FERM and PDZ domain containing 3 [Homo
sapiens]
Length = 1662
Score = 27.3 bits (59), Expect = 4.0
Identities = 17/64 (26%), Positives = 29/64 (45%), Gaps = 5/64 (7%)
Query: 43 ISPQEVGVLTGPDRHTFLQAGLSVGGRRCCVIRDHLLAEGDGVLDARTKGLDARAVCVGR 102
+ P G L G + +LQ GR C +R + +G G+ + + D + +C G
Sbjct: 1139 LKPPSQGELPGTE---YLQP--PAPGRCSCQLRSSPVQQGPGMSREQRRSCDCKRICRGG 1193
Query: 103 APRA 106
P+A
Sbjct: 1194 RPQA 1197
>gi|89060961 PREDICTED: FERM and PDZ domain containing 3 [Homo
sapiens]
Length = 1810
Score = 27.3 bits (59), Expect = 4.0
Identities = 17/64 (26%), Positives = 29/64 (45%), Gaps = 5/64 (7%)
Query: 43 ISPQEVGVLTGPDRHTFLQAGLSVGGRRCCVIRDHLLAEGDGVLDARTKGLDARAVCVGR 102
+ P G L G + +LQ GR C +R + +G G+ + + D + +C G
Sbjct: 1287 LKPPSQGELPGTE---YLQP--PAPGRCSCQLRSSPVQQGPGMSREQRRSCDCKRICRGG 1341
Query: 103 APRA 106
P+A
Sbjct: 1342 RPQA 1345
>gi|89059963 PREDICTED: FERM and PDZ domain containing 3 [Homo
sapiens]
Length = 1810
Score = 27.3 bits (59), Expect = 4.0
Identities = 17/64 (26%), Positives = 29/64 (45%), Gaps = 5/64 (7%)
Query: 43 ISPQEVGVLTGPDRHTFLQAGLSVGGRRCCVIRDHLLAEGDGVLDARTKGLDARAVCVGR 102
+ P G L G + +LQ GR C +R + +G G+ + + D + +C G
Sbjct: 1287 LKPPSQGELPGTE---YLQP--PAPGRCSCQLRSSPVQQGPGMSREQRRSCDCKRICRGG 1341
Query: 103 APRA 106
P+A
Sbjct: 1342 RPQA 1345
>gi|239751469 PREDICTED: hypothetical protein [Homo sapiens]
Length = 278
Score = 26.2 bits (56), Expect = 9.0
Identities = 9/18 (50%), Positives = 13/18 (72%)
Query: 28 NSCVWASRPGGLLAAISP 45
+SC+W SR G+ A+SP
Sbjct: 141 SSCLWCSRKPGMCTALSP 158
>gi|14589937 protocadherin 8 isoform 2 precursor [Homo sapiens]
Length = 973
Score = 26.2 bits (56), Expect = 9.0
Identities = 13/28 (46%), Positives = 17/28 (60%), Gaps = 1/28 (3%)
Query: 81 EGDGVLDARTKGLDARAVCVGRAPRALL 108
EGDG L GLD +C G+AP+ +L
Sbjct: 78 EGDGQLTVGDAGLDRERLC-GQAPQCVL 104
>gi|6631102 protocadherin 8 isoform 1 precursor [Homo sapiens]
Length = 1070
Score = 26.2 bits (56), Expect = 9.0
Identities = 13/28 (46%), Positives = 17/28 (60%), Gaps = 1/28 (3%)
Query: 81 EGDGVLDARTKGLDARAVCVGRAPRALL 108
EGDG L GLD +C G+AP+ +L
Sbjct: 78 EGDGQLTVGDAGLDRERLC-GQAPQCVL 104
>gi|47578107 delangin isoform B [Homo sapiens]
Length = 2697
Score = 26.2 bits (56), Expect = 9.0
Identities = 13/43 (30%), Positives = 22/43 (51%)
Query: 82 GDGVLDARTKGLDARAVCVGRAPRALLVLMGRRGVHGGILNKT 124
G+ + RTK + + V P L L +RGVHG +++ +
Sbjct: 1782 GENAIAVRTKAMKCLSEVVAVDPSILARLDMQRGVHGRLMDNS 1824
>gi|47578105 delangin isoform A [Homo sapiens]
Length = 2804
Score = 26.2 bits (56), Expect = 9.0
Identities = 13/43 (30%), Positives = 22/43 (51%)
Query: 82 GDGVLDARTKGLDARAVCVGRAPRALLVLMGRRGVHGGILNKT 124
G+ + RTK + + V P L L +RGVHG +++ +
Sbjct: 1782 GENAIAVRTKAMKCLSEVVAVDPSILARLDMQRGVHGRLMDNS 1824
>gi|30089935 transmembrane protein 132A isoform a [Homo sapiens]
Length = 1024
Score = 26.2 bits (56), Expect = 9.0
Identities = 13/28 (46%), Positives = 16/28 (57%)
Query: 77 HLLAEGDGVLDARTKGLDARAVCVGRAP 104
HL+A VLD+R L+ V VGR P
Sbjct: 580 HLVAPHARVLDSRVASLEGGRVVVGREP 607
>gi|30089937 transmembrane protein 132A isoform b [Homo sapiens]
Length = 1023
Score = 26.2 bits (56), Expect = 9.0
Identities = 13/28 (46%), Positives = 16/28 (57%)
Query: 77 HLLAEGDGVLDARTKGLDARAVCVGRAP 104
HL+A VLD+R L+ V VGR P
Sbjct: 579 HLVAPHARVLDSRVASLEGGRVVVGREP 606
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.325 0.142 0.443
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 5,278,653
Number of Sequences: 37866
Number of extensions: 222659
Number of successful extensions: 490
Number of sequences better than 10.0: 25
Number of HSP's better than 10.0 without gapping: 20
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 465
Number of HSP's gapped (non-prelim): 25
length of query: 137
length of database: 18,247,518
effective HSP length: 91
effective length of query: 46
effective length of database: 14,801,712
effective search space: 680878752
effective search space used: 680878752
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 56 (26.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.