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Search of human proteins with 7019555
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7019555 transmembrane protein 2 isoform a [Homo sapiens]
(1383 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7019555 transmembrane protein 2 isoform a [Homo sapiens] 2830 0.0
gi|209447096 transmembrane protein 2 isoform b [Homo sapiens] 2199 0.0
gi|38638698 KIAA1199 [Homo sapiens] 896 0.0
gi|126116589 fibrocystin L [Homo sapiens] 166 1e-40
gi|126131104 fibrocystin isoform 2 [Homo sapiens] 66 2e-10
gi|126131102 fibrocystin isoform 1 [Homo sapiens] 66 2e-10
gi|210147552 O-linked mannose beta1,2-N-acetylglucosaminyltransf... 49 3e-05
gi|20270363 family with sequence similarity 3, member D [Homo sa... 44 0.001
gi|13324682 family 3, member A protein [Homo sapiens] 42 0.003
gi|91807125 family with sequence similarity 3, member C precurso... 42 0.005
gi|7661714 family with sequence similarity 3, member C precursor... 42 0.005
gi|46255032 family with sequence similarity 3, member B isoform ... 37 0.10
gi|46255030 family with sequence similarity 3, member B isoform ... 37 0.10
gi|29294649 dicer1 [Homo sapiens] 32 3.2
gi|29294651 dicer1 [Homo sapiens] 32 3.2
gi|78042577 MAP7 domain containing 1 [Homo sapiens] 32 4.2
gi|94400925 synaptonemal complex protein 2-like [Homo sapiens] 32 5.5
gi|37537554 hypothetical protein FLJ37538 [Homo sapiens] 32 5.5
gi|62422571 collapsin response mediator protein 1 isoform 1 [Hom... 31 7.2
gi|4503051 collapsin response mediator protein 1 isoform 2 [Homo... 31 7.2
gi|21493039 A-kinase anchor protein 4 isoform 2 [Homo sapiens] 31 9.4
gi|21493037 A-kinase anchor protein 4 isoform 1 [Homo sapiens] 31 9.4
>gi|7019555 transmembrane protein 2 isoform a [Homo sapiens]
Length = 1383
Score = 2830 bits (7337), Expect = 0.0
Identities = 1383/1383 (100%), Positives = 1383/1383 (100%)
Query: 1 MYATDSRGHSPAFLQPQNGNSRHPSGYVPGKVVPLRPPPPPKSQASAKFTSIRREDRATF 60
MYATDSRGHSPAFLQPQNGNSRHPSGYVPGKVVPLRPPPPPKSQASAKFTSIRREDRATF
Sbjct: 1 MYATDSRGHSPAFLQPQNGNSRHPSGYVPGKVVPLRPPPPPKSQASAKFTSIRREDRATF 60
Query: 61 AFSPEEQQAQRESQKQKRHKNTFICFAITSFSFFIALAIILGISSKYAPDENCPDQNPRL 120
AFSPEEQQAQRESQKQKRHKNTFICFAITSFSFFIALAIILGISSKYAPDENCPDQNPRL
Sbjct: 61 AFSPEEQQAQRESQKQKRHKNTFICFAITSFSFFIALAIILGISSKYAPDENCPDQNPRL 120
Query: 121 RNWDPGQDSAKQVVIKEGDMLRLTSDATVHSIVIQDGGLLVFGDNKDGSRNITLRTHYIL 180
RNWDPGQDSAKQVVIKEGDMLRLTSDATVHSIVIQDGGLLVFGDNKDGSRNITLRTHYIL
Sbjct: 121 RNWDPGQDSAKQVVIKEGDMLRLTSDATVHSIVIQDGGLLVFGDNKDGSRNITLRTHYIL 180
Query: 181 IQDGGALHIGAEKCRYKSKATITLYGKSDEGESMPTFGKKFIGVEAGGTLELHGARKASW 240
IQDGGALHIGAEKCRYKSKATITLYGKSDEGESMPTFGKKFIGVEAGGTLELHGARKASW
Sbjct: 181 IQDGGALHIGAEKCRYKSKATITLYGKSDEGESMPTFGKKFIGVEAGGTLELHGARKASW 240
Query: 241 TLLARTLNSSGLPFGSYTFEKDFSRGLNVRVIDQDTAKILESERFDTHEYRNESRRLQEF 300
TLLARTLNSSGLPFGSYTFEKDFSRGLNVRVIDQDTAKILESERFDTHEYRNESRRLQEF
Sbjct: 241 TLLARTLNSSGLPFGSYTFEKDFSRGLNVRVIDQDTAKILESERFDTHEYRNESRRLQEF 300
Query: 301 LRFQDPGRIVAIAVGDSAAKSLLQGTIQMIQERLGSELIQGLGYRQAWALVGVIDGGSTS 360
LRFQDPGRIVAIAVGDSAAKSLLQGTIQMIQERLGSELIQGLGYRQAWALVGVIDGGSTS
Sbjct: 301 LRFQDPGRIVAIAVGDSAAKSLLQGTIQMIQERLGSELIQGLGYRQAWALVGVIDGGSTS 360
Query: 361 CNESVRNYENHSSGGKALAQREFYTVDGQKFSVTAYSEWIEGVSLSGFRVEVVDGVKLNL 420
CNESVRNYENHSSGGKALAQREFYTVDGQKFSVTAYSEWIEGVSLSGFRVEVVDGVKLNL
Sbjct: 361 CNESVRNYENHSSGGKALAQREFYTVDGQKFSVTAYSEWIEGVSLSGFRVEVVDGVKLNL 420
Query: 421 LDDVSSWKPGDQIVVASTDYSMYQAEEFTLLPCSECSHFQVKVKETPQFLHMGEIIDGVD 480
LDDVSSWKPGDQIVVASTDYSMYQAEEFTLLPCSECSHFQVKVKETPQFLHMGEIIDGVD
Sbjct: 421 LDDVSSWKPGDQIVVASTDYSMYQAEEFTLLPCSECSHFQVKVKETPQFLHMGEIIDGVD 480
Query: 481 MRAEVGILTRNIVIQGEVEDSCYAENQCQFFDYDTFGGHIMIMKNFTSVHLSYVELKHMG 540
MRAEVGILTRNIVIQGEVEDSCYAENQCQFFDYDTFGGHIMIMKNFTSVHLSYVELKHMG
Sbjct: 481 MRAEVGILTRNIVIQGEVEDSCYAENQCQFFDYDTFGGHIMIMKNFTSVHLSYVELKHMG 540
Query: 541 QQQMGRYPVHFHLCGDVDYKGGYRHATFVDGLSIHHSFSRCITVHGTNGLLIKDTIGFDT 600
QQQMGRYPVHFHLCGDVDYKGGYRHATFVDGLSIHHSFSRCITVHGTNGLLIKDTIGFDT
Sbjct: 541 QQQMGRYPVHFHLCGDVDYKGGYRHATFVDGLSIHHSFSRCITVHGTNGLLIKDTIGFDT 600
Query: 601 LGHCFFLEDGIEQRNTLFHNLGLLTKPGTLLPTDRNNSMCTTMRDKVFGNYIPVPATDCM 660
LGHCFFLEDGIEQRNTLFHNLGLLTKPGTLLPTDRNNSMCTTMRDKVFGNYIPVPATDCM
Sbjct: 601 LGHCFFLEDGIEQRNTLFHNLGLLTKPGTLLPTDRNNSMCTTMRDKVFGNYIPVPATDCM 660
Query: 661 AVSTFWIAHPNNNLINNAAAGSQDAGIWYLFHKEPTGESSGLQLLAKPELTPLGIFYNNR 720
AVSTFWIAHPNNNLINNAAAGSQDAGIWYLFHKEPTGESSGLQLLAKPELTPLGIFYNNR
Sbjct: 661 AVSTFWIAHPNNNLINNAAAGSQDAGIWYLFHKEPTGESSGLQLLAKPELTPLGIFYNNR 720
Query: 721 VHSNFKAGLFIDKGVKTTNSSAADPREYLCLDNSARFRPHQDANPEKPRVAALIDRLIAF 780
VHSNFKAGLFIDKGVKTTNSSAADPREYLCLDNSARFRPHQDANPEKPRVAALIDRLIAF
Sbjct: 721 VHSNFKAGLFIDKGVKTTNSSAADPREYLCLDNSARFRPHQDANPEKPRVAALIDRLIAF 780
Query: 781 KNNDNGAWVRGGDIIVQNSAFADNGIGLTFASDGSFPSDEGSSQEVSESLFVGESRNYGF 840
KNNDNGAWVRGGDIIVQNSAFADNGIGLTFASDGSFPSDEGSSQEVSESLFVGESRNYGF
Sbjct: 781 KNNDNGAWVRGGDIIVQNSAFADNGIGLTFASDGSFPSDEGSSQEVSESLFVGESRNYGF 840
Query: 841 QGGQNKYVGTGGIDQKPRTLPRNRTFPIRGFQIYDGPIHLTRSTFKKYVPTPDRYSSAIG 900
QGGQNKYVGTGGIDQKPRTLPRNRTFPIRGFQIYDGPIHLTRSTFKKYVPTPDRYSSAIG
Sbjct: 841 QGGQNKYVGTGGIDQKPRTLPRNRTFPIRGFQIYDGPIHLTRSTFKKYVPTPDRYSSAIG 900
Query: 901 FLMKNSWQITPRNNISLVKFGPHVSLNVFFGKPGPWFEDCEMDGDKNSIFHDIDGSVTGY 960
FLMKNSWQITPRNNISLVKFGPHVSLNVFFGKPGPWFEDCEMDGDKNSIFHDIDGSVTGY
Sbjct: 901 FLMKNSWQITPRNNISLVKFGPHVSLNVFFGKPGPWFEDCEMDGDKNSIFHDIDGSVTGY 960
Query: 961 KDAYVGRMDNYLIRHPSCVNVSKWNAVICSGTYAQVYVQTWSTQNLSMTITRDEYPSNPM 1020
KDAYVGRMDNYLIRHPSCVNVSKWNAVICSGTYAQVYVQTWSTQNLSMTITRDEYPSNPM
Sbjct: 961 KDAYVGRMDNYLIRHPSCVNVSKWNAVICSGTYAQVYVQTWSTQNLSMTITRDEYPSNPM 1020
Query: 1021 VLRGINQKAAFPQYQPVVMLEKGYTIHWNGPAPRTTFLYLVNFNKNDWIRVGLCYPSNTS 1080
VLRGINQKAAFPQYQPVVMLEKGYTIHWNGPAPRTTFLYLVNFNKNDWIRVGLCYPSNTS
Sbjct: 1021 VLRGINQKAAFPQYQPVVMLEKGYTIHWNGPAPRTTFLYLVNFNKNDWIRVGLCYPSNTS 1080
Query: 1081 FQVTFGYLQRQNGSLSKIEEYEPVHSLEELQRKQSERKFYFDSSTGLLFLYLKAKSHRHG 1140
FQVTFGYLQRQNGSLSKIEEYEPVHSLEELQRKQSERKFYFDSSTGLLFLYLKAKSHRHG
Sbjct: 1081 FQVTFGYLQRQNGSLSKIEEYEPVHSLEELQRKQSERKFYFDSSTGLLFLYLKAKSHRHG 1140
Query: 1141 HSYCSSQGCERVKIQAATDSKDISNCMAKAYPQYYRKPSVVKRMPAMLTGLCQGCGTRQV 1200
HSYCSSQGCERVKIQAATDSKDISNCMAKAYPQYYRKPSVVKRMPAMLTGLCQGCGTRQV
Sbjct: 1141 HSYCSSQGCERVKIQAATDSKDISNCMAKAYPQYYRKPSVVKRMPAMLTGLCQGCGTRQV 1200
Query: 1201 VFTSDPHKSYLPVQFQSPDKAETQRGDPSVISVNGTDFTFRSAGVLLLVVDPCSVPFRLT 1260
VFTSDPHKSYLPVQFQSPDKAETQRGDPSVISVNGTDFTFRSAGVLLLVVDPCSVPFRLT
Sbjct: 1201 VFTSDPHKSYLPVQFQSPDKAETQRGDPSVISVNGTDFTFRSAGVLLLVVDPCSVPFRLT 1260
Query: 1261 EKTVFPLADVSRIEEYLKTGIPPRSIVLLSTRGEIKQLNISHLLVPLGLAKPAHLYDKGS 1320
EKTVFPLADVSRIEEYLKTGIPPRSIVLLSTRGEIKQLNISHLLVPLGLAKPAHLYDKGS
Sbjct: 1261 EKTVFPLADVSRIEEYLKTGIPPRSIVLLSTRGEIKQLNISHLLVPLGLAKPAHLYDKGS 1320
Query: 1321 TIFLGFSGNFKPSWTKLFTSPAGQGLGVLEQFIPLQLDEYGCPRATTVRRRDLELLKQAS 1380
TIFLGFSGNFKPSWTKLFTSPAGQGLGVLEQFIPLQLDEYGCPRATTVRRRDLELLKQAS
Sbjct: 1321 TIFLGFSGNFKPSWTKLFTSPAGQGLGVLEQFIPLQLDEYGCPRATTVRRRDLELLKQAS 1380
Query: 1381 KAH 1383
KAH
Sbjct: 1381 KAH 1383
>gi|209447096 transmembrane protein 2 isoform b [Homo sapiens]
Length = 1320
Score = 2199 bits (5697), Expect = 0.0
Identities = 1131/1401 (80%), Positives = 1179/1401 (84%), Gaps = 99/1401 (7%)
Query: 1 MYATDSRGHSPAFLQPQNGNSRHPSGYVPGKVVPLRPPPPPKSQASAKFTSIRREDRATF 60
MYATDSRGHSPAFLQPQNGNSRHPSGYVPGKVVPLRPPPPPKSQASAKFTSIRREDRATF
Sbjct: 1 MYATDSRGHSPAFLQPQNGNSRHPSGYVPGKVVPLRPPPPPKSQASAKFTSIRREDRATF 60
Query: 61 AFSPEEQQAQRESQKQKRHKNTFICFAITSFSFFIALAIILGISSKYAPDENCPDQNPRL 120
AFSPEEQQAQRESQKQKRHKNTFICFAITSFSFFIALAIILGISSKYAPDENCPDQNPRL
Sbjct: 61 AFSPEEQQAQRESQKQKRHKNTFICFAITSFSFFIALAIILGISSKYAPDENCPDQNPRL 120
Query: 121 RNWDPGQDSAKQVVIKEGDMLRLTSDATVHSIVIQDGGLLVFGDNKDGSRNITLRTHYIL 180
RNWDPGQDSAKQVVIKEGDMLRLTSDATVHSIVIQD
Sbjct: 121 RNWDPGQDSAKQVVIKEGDMLRLTSDATVHSIVIQD------------------------ 156
Query: 181 IQDGGALHIGAEKCRYKSKATITLYGKSDEGESMPTFGKKFIGVEAGGTLELHGAR---- 236
GG L ++G + +G T +I ++ GG L + +
Sbjct: 157 ---GGLL----------------VFGDNKDGSRNITLRTHYILIQDGGALHIGAEKCRYK 197
Query: 237 -KASWTLLARTLNSSGLP-FGSYTFEKDFSRGLNVRVIDQDT----AKILESERFDTHEY 290
KA+ TL ++ +P FG + L + + + A+ L S Y
Sbjct: 198 SKATITLYGKSDEGESMPTFGKKFIGVEAGGTLELHGARKASWTLLARTLNSSGLPFGSY 257
Query: 291 RNESRRLQEFLRFQDPGRIVAIAVGDSAAKSLLQGTIQMIQERLGSELIQG-LGYRQAWA 349
E ++F R G V + + AK L + R S +Q L ++
Sbjct: 258 TFE----KDFSR----GLNVRV-IDQDTAKILESERFDTHEYRNESRRLQEFLRFQDPGR 308
Query: 350 LVGVIDGGSTSCNESVRNYENHSSGGKALAQREFYTVDGQKFSVTAYSEWIEGVSLSGFR 409
+V + G S + K+L Q Q SE I+G+ G+R
Sbjct: 309 IVAIAVGDSAA---------------KSLLQGTI-----QMIQERLGSELIQGL---GYR 345
Query: 410 -----VEVVDGVKLNLLDDVSSWKPGDQ--IVVASTDYSMYQAEEFTLLPCSECSHFQVK 462
V V+DG + + V +++ +A ++ ++F++ SE
Sbjct: 346 QAWALVGVIDGGSTSCNESVRNYENHSSGGKALAQREFYTVDGQKFSVTAYSEW------ 399
Query: 463 VKETPQFLHMGEIIDGVDMRAEVGILTRNIVIQGEVEDSCYAENQCQFFDYDTFGGHIMI 522
++ETPQFLHMGEIIDGVDMRAEVGILTRNIVIQGEVEDSCYAENQCQFFDYDTFGGHIMI
Sbjct: 400 IEETPQFLHMGEIIDGVDMRAEVGILTRNIVIQGEVEDSCYAENQCQFFDYDTFGGHIMI 459
Query: 523 MKNFTSVHLSYVELKHMGQQQMGRYPVHFHLCGDVDYKGGYRHATFVDGLSIHHSFSRCI 582
MKNFTSVHLSYVELKHMGQQQMGRYPVHFHLCGDVDYKGGYRHATFVDGLSIHHSFSRCI
Sbjct: 460 MKNFTSVHLSYVELKHMGQQQMGRYPVHFHLCGDVDYKGGYRHATFVDGLSIHHSFSRCI 519
Query: 583 TVHGTNGLLIKDTIGFDTLGHCFFLEDGIEQRNTLFHNLGLLTKPGTLLPTDRNNSMCTT 642
TVHGTNGLLIKDTIGFDTLGHCFFLEDGIEQRNTLFHNLGLLTKPGTLLPTDRNNSMCTT
Sbjct: 520 TVHGTNGLLIKDTIGFDTLGHCFFLEDGIEQRNTLFHNLGLLTKPGTLLPTDRNNSMCTT 579
Query: 643 MRDKVFGNYIPVPATDCMAVSTFWIAHPNNNLINNAAAGSQDAGIWYLFHKEPTGESSGL 702
MRDKVFGNYIPVPATDCMAVSTFWIAHPNNNLINNAAAGSQDAGIWYLFHKEPTGESSGL
Sbjct: 580 MRDKVFGNYIPVPATDCMAVSTFWIAHPNNNLINNAAAGSQDAGIWYLFHKEPTGESSGL 639
Query: 703 QLLAKPELTPLGIFYNNRVHSNFKAGLFIDKGVKTTNSSAADPREYLCLDNSARFRPHQD 762
QLLAKPELTPLGIFYNNRVHSNFKAGLFIDKGVKTTNSSAADPREYLCLDNSARFRPHQD
Sbjct: 640 QLLAKPELTPLGIFYNNRVHSNFKAGLFIDKGVKTTNSSAADPREYLCLDNSARFRPHQD 699
Query: 763 ANPEKPRVAALIDRLIAFKNNDNGAWVRGGDIIVQNSAFADNGIGLTFASDGSFPSDEGS 822
ANPEKPRVAALIDRLIAFKNNDNGAWVRGGDIIVQNSAFADNGIGLTFASDGSFPSDEGS
Sbjct: 700 ANPEKPRVAALIDRLIAFKNNDNGAWVRGGDIIVQNSAFADNGIGLTFASDGSFPSDEGS 759
Query: 823 SQEVSESLFVGESRNYGFQGGQNKYVGTGGIDQKPRTLPRNRTFPIRGFQIYDGPIHLTR 882
SQEVSESLFVGESRNYGFQGGQNKYVGTGGIDQKPRTLPRNRTFPIRGFQIYDGPIHLTR
Sbjct: 760 SQEVSESLFVGESRNYGFQGGQNKYVGTGGIDQKPRTLPRNRTFPIRGFQIYDGPIHLTR 819
Query: 883 STFKKYVPTPDRYSSAIGFLMKNSWQITPRNNISLVKFGPHVSLNVFFGKPGPWFEDCEM 942
STFKKYVPTPDRYSSAIGFLMKNSWQITPRNNISLVKFGPHVSLNVFFGKPGPWFEDCEM
Sbjct: 820 STFKKYVPTPDRYSSAIGFLMKNSWQITPRNNISLVKFGPHVSLNVFFGKPGPWFEDCEM 879
Query: 943 DGDKNSIFHDIDGSVTGYKDAYVGRMDNYLIRHPSCVNVSKWNAVICSGTYAQVYVQTWS 1002
DGDKNSIFHDIDGSVTGYKDAYVGRMDNYLIRHPSCVNVSKWNAVICSGTYAQVYVQTWS
Sbjct: 880 DGDKNSIFHDIDGSVTGYKDAYVGRMDNYLIRHPSCVNVSKWNAVICSGTYAQVYVQTWS 939
Query: 1003 TQNLSMTITRDEYPSNPMVLRGINQKAAFPQYQPVVMLEKGYTIHWNGPAPRTTFLYLVN 1062
TQNLSMTITRDEYPSNPMVLRGINQKAAFPQYQPVVMLEKGYTIHWNGPAPRTTFLYLVN
Sbjct: 940 TQNLSMTITRDEYPSNPMVLRGINQKAAFPQYQPVVMLEKGYTIHWNGPAPRTTFLYLVN 999
Query: 1063 FNKNDWIRVGLCYPSNTSFQVTFGYLQRQNGSLSKIEEYEPVHSLEELQRKQSERKFYFD 1122
FNKNDWIRVGLCYPSNTSFQVTFGYLQRQNGSLSKIEEYEPVHSLEELQRKQSERKFYFD
Sbjct: 1000 FNKNDWIRVGLCYPSNTSFQVTFGYLQRQNGSLSKIEEYEPVHSLEELQRKQSERKFYFD 1059
Query: 1123 SSTGLLFLYLKAKSHRHGHSYCSSQGCERVKIQAATDSKDISNCMAKAYPQYYRKPSVVK 1182
SSTGLLFLYLKAKSHRHGHSYCSSQGCERVKIQAATDSKDISNCMAKAYPQYYRKPSVVK
Sbjct: 1060 SSTGLLFLYLKAKSHRHGHSYCSSQGCERVKIQAATDSKDISNCMAKAYPQYYRKPSVVK 1119
Query: 1183 RMPAMLTGLCQGCGTRQVVFTSDPHKSYLPVQFQSPDKAETQRGDPSVISVNGTDFTFRS 1242
RMPAMLTGLCQGCGTRQVVFTSDPHKSYLPVQFQSPDKAETQRGDPSVISVNGTDFTFRS
Sbjct: 1120 RMPAMLTGLCQGCGTRQVVFTSDPHKSYLPVQFQSPDKAETQRGDPSVISVNGTDFTFRS 1179
Query: 1243 AGVLLLVVDPCSVPFRLTEKTVFPLADVSRIEEYLKTGIPPRSIVLLSTRGEIKQLNISH 1302
AGVLLLVVDPCSVPFRLTEKTVFPLADVSRIEEYLKTGIPPRSIVLLSTRGEIKQLNISH
Sbjct: 1180 AGVLLLVVDPCSVPFRLTEKTVFPLADVSRIEEYLKTGIPPRSIVLLSTRGEIKQLNISH 1239
Query: 1303 LLVPLGLAKPAHLYDKGSTIFLGFSGNFKPSWTKLFTSPAGQGLGVLEQFIPLQLDEYGC 1362
LLVPLGLAKPAHLYDKGSTIFLGFSGNFKPSWTKLFTSPAGQGLGVLEQFIPLQLDEYGC
Sbjct: 1240 LLVPLGLAKPAHLYDKGSTIFLGFSGNFKPSWTKLFTSPAGQGLGVLEQFIPLQLDEYGC 1299
Query: 1363 PRATTVRRRDLELLKQASKAH 1383
PRATTVRRRDLELLKQASKAH
Sbjct: 1300 PRATTVRRRDLELLKQASKAH 1320
>gi|38638698 KIAA1199 [Homo sapiens]
Length = 1361
Score = 896 bits (2315), Expect = 0.0
Identities = 455/939 (48%), Positives = 615/939 (65%), Gaps = 29/939 (3%)
Query: 413 VDGVKLNLLDDVSSWKPGDQIVVASTDYSMYQAEEFTLLPCSECSHFQVKVKETPQFLHM 472
V+ LNL D+V SWKPGD +V+ASTDYSMYQAEEF +LPC C+ QVKV P +LH+
Sbjct: 419 VNSTILNLEDNVQSWKPGDTLVIASTDYSMYQAEEFQVLPCRSCAPNQVKVAGKPMYLHI 478
Query: 473 GEIIDGVDMRAEVGILTRNIVIQGEVEDSCYAENQ--CQFFDYDTFGGHIMIMKNFTSVH 530
GE IDGVDMRAEVG+L+RNI++ GE+ED CY C FFD+DTFGGHI F + H
Sbjct: 479 GEEIDGVDMRAEVGLLSRNIIVMGEMEDKCYPYRNHICNFFDFDTFGGHIKFALGFKAAH 538
Query: 531 LSYVELKHMGQQQMGRYPVHFHLCGDVDYKGGYRHATFVDGLSIHHSFSRCITVHGTNGL 590
L ELKHMGQQ +G+YP+HFHL GDVD +GGY T++ LSIHH+FSRC+TVHG+NGL
Sbjct: 539 LEGTELKHMGQQLVGQYPIHFHLAGDVDERGGYDPPTYIRDLSIHHTFSRCVTVHGSNGL 598
Query: 591 LIKDTIGFDTLGHCFFLEDGIEQRNTLFHNLGLLTKPGTLLPTDRNNSMCTTMRDKVFGN 650
LIKD +G+++LGHCFF EDG E+RNT H LGLL K GTLLP+DR++ MC + + +
Sbjct: 599 LIKDVVGYNSLGHCFFTEDGPEERNTFDHCLGLLVKSGTLLPSDRDSKMCKMITEDSYPG 658
Query: 651 YIPVPATDCMAVSTFWIAHPNNNLINNAAAGSQDAGIWYLFHKEPTGESSGLQLLAKPEL 710
YIP P DC AVSTFW+A+PNNNLIN AAAGS++ G W++FH PTG S G+ E
Sbjct: 659 YIPKPRQDCNAVSTFWMANPNNNLINCAAAGSEETGFWFIFHHVPTGPSVGMYSPGYSEH 718
Query: 711 TPLGIFYNNRVHSNFKAGLFIDKGVKTTNSSAADPREYLCLDNSARFRPHQDANPEKPRV 770
PLG FYNNR HSN++AG+ ID GVKTT +SA D R +L + SAR+ PHQDA+P KPR
Sbjct: 719 IPLGKFYNNRAHSNYRAGMIIDNGVKTTEASAKDKRPFLSI-ISARYSPHQDADPLKPRE 777
Query: 771 AALIDRLIAFKNNDNGAWVRGGDIIVQNSAFADNGIGLTFASDGSFPSDEGSSQEVSESL 830
A+I IA+KN D+GAW+RGGD+ + + FADNGIGLT AS G+FP D+GS QE+ SL
Sbjct: 778 PAIIRHFIAYKNQDHGAWLRGGDVWLDSCRFADNGIGLTLASGGTFPYDDGSKQEIKNSL 837
Query: 831 FVGESRNYGFQGGQNKYVGTGGIDQKPRTLPRNRTFPIRGFQIYDGPIHLTRSTFKKYVP 890
FVGES N G + N+ G GG+D RTLP + FPIRG Q+YDGPI++ TF+K+V
Sbjct: 838 FVGESGNVGTEMMDNRIWGPGGLDHSGRTLPIGQNFPIRGIQLYDGPINIQNCTFRKFVA 897
Query: 891 TPDRYSSAIGFLMKNSWQITPRNNISLVKF-GPHVSLNVFFGKPGPWFEDCEMDGDKNSI 949
R++SA+ F + N+WQ P NN++ + F ++ VFFG+PGPWF +MDGDK S+
Sbjct: 898 LEGRHTSALAFRLNNAWQSCPHNNVTGIAFEDVPITSRVFFGEPGPWFNQLDMDGDKTSV 957
Query: 950 FHDIDGSVTGYKDAYVGRMDNYLIRHPSCVNVSKWNAVICSGTYAQVYVQTWSTQNLSMT 1009
FHD+DGSV+ Y +Y+ + DN+L+RHP C+NV W ICSG YAQ+Y+Q + T NL M
Sbjct: 958 FHDVDGSVSEYPGSYLTKNDNWLVRHPDCINVPDWRGAICSGCYAQMYIQAYKTSNLRMK 1017
Query: 1010 ITRDEYPSNPMVLRG-INQKAAFPQYQPVVMLEKGYTIHWNGPAPRTTFLYLVNFNKNDW 1068
I ++++PS+P+ L G + + + QYQPVV L+KGYTIHW+ AP ++L+NFNK DW
Sbjct: 1018 IIKNDFPSHPLYLEGALTRSTHYQQYQPVVTLQKGYTIHWDQTAPAELAIWLINFNKGDW 1077
Query: 1069 IRVGLCYPSNTSFQVTFGYLQRQNGSLSKIEEYEPVHSLEELQRKQSERK-FYFDSSTGL 1127
IRVGLCYP T+F + R SK + ++++++ R +Y+D +GL
Sbjct: 1078 IRVGLCYPRGTTFSILSDVHNRLLKQTSKTGVFVRTLQMDKVEQSYPGRSHYYWDEDSGL 1137
Query: 1128 LFLYLKAKSHRHGHSYCSSQGCERVKIQA-ATDSKDISNCMAKAYPQYYRKPSVVKRMPA 1186
LFL LKA++ R ++CS +GCER+KI+A + +S+C A AYP++ + V MP
Sbjct: 1138 LFLKLKAQNEREKFAFCSMKGCERIKIKALIPKNAGVSDCTATAYPKFTERAVVDVPMPK 1197
Query: 1187 MLTGLCQGCGTRQVVFTSDPHKSYLPVQFQSPDKAETQR-GDPSVISVNGTDFTFRSAGV 1245
L G + T D +L V+ +S + D + I V+G + G+
Sbjct: 1198 KLFG--------SQLKTKD---HFLEVKMESSKQHFFHLWNDFAYIEVDGKKYPSSEDGI 1246
Query: 1246 LLLVVDPCSVPFRLTEKTVFPLADVSRIE----EYLKTGIPPRSIVLLSTRGE-IKQLNI 1300
++V+D R+ T F + + I Y+ T IP SIVL++++G + +
Sbjct: 1247 QVVVID--GNQGRVVSHTSFRNSILQGIPWQLFNYVAT-IPDNSIVLMASKGRYVSRGPW 1303
Query: 1301 SHLLVPLGLAKPAHLYDKGSTIFLGFSGNFKPSWTKLFT 1339
+ +L LG + L K F+GF G+F+P W L T
Sbjct: 1304 TRVLEKLGADRGLKL--KEQMAFVGFKGSFRPIWVTLDT 1340
Score = 218 bits (554), Expect = 4e-56
Identities = 127/326 (38%), Positives = 186/326 (57%), Gaps = 10/326 (3%)
Query: 80 KNTFICFAITSFSFFIALAIILGISSKYAPDENCPDQNPRLRNWDPGQDSAKQVVIKEGD 139
+ F+ A+ + S+ + L G +S A CPDQ+P L+ W+PG D V I +G
Sbjct: 6 RQDFLFKAMLTISW-LTLTCFPGATSTVAA--GCPDQSPELQPWNPGHDQDHHVHIGQGK 62
Query: 140 MLRLTSDATVHSIVIQDGGLLVFGDNKDGSRNITLRTHYILIQDGGALHIGAEKCRYKSK 199
L LTS ATV+SI I +GG LV KD I LRT +ILI +GG LH G+ C ++
Sbjct: 63 TLLLTSSATVYSIHISEGGKLVI---KDHDEPIVLRTRHILIDNGGELHAGSALCPFQGN 119
Query: 200 ATITLYGKSDEG-ESMPTFGKKFIGVEAGGTLELHGARKASWTLLARTLNSSGLPFGSYT 258
TI LYG++DEG + P +G K+IGV GG LELHG +K SWT L +TL+ G+ G Y
Sbjct: 120 FTIILYGRADEGIQPDPYYGLKYIGVGKGGALELHGQKKLSWTFLNKTLHPGGMAEGGYF 179
Query: 259 FEKDFS-RGLNVRVIDQDTAKILESERFDTHEYRNESRRLQEFLRFQDPGRIVAIAVGDS 317
FE+ + RG+ V VID + ++ S+RFDT+ + ES RL ++L GRI+++AV D
Sbjct: 180 FERSWGHRGVIVHVIDPKSGTVIHSDRFDTYRSKKESERLVQYLNAVPDGRILSVAVNDE 239
Query: 318 AAKSLLQGTIQMIQERLGSELIQGLGYRQAWALVGVIDGGSTSCNESVRNYENHSSGGKA 377
+++ L + +LGS+ LG+R W+ + V S+S + + Y H A
Sbjct: 240 GSRN-LDDMARKAMTKLGSKHFLHLGFRHPWSFLTVKGNPSSSVEDHI-EYHGHRGSAAA 297
Query: 378 LAQREFYTVDGQKFSVTAYSEWIEGV 403
+ F T G+ F+V+ SEW++ V
Sbjct: 298 RVFKLFQTEHGEYFNVSLSSEWVQDV 323
>gi|126116589 fibrocystin L [Homo sapiens]
Length = 4243
Score = 166 bits (421), Expect = 1e-40
Identities = 109/350 (31%), Positives = 164/350 (46%), Gaps = 65/350 (18%)
Query: 415 GVKLNLLDDVSSWKPGDQIVVASTDYSMYQAEEFTLLPCS-ECSHFQVKVKETPQFLHMG 473
G ++ +L + +WKPGD IV+AST + Q E + S + + + H+G
Sbjct: 2309 GERILILQEAVTWKPGDNIVIASTGHRHSQGENEKMTIASVSADGINITLSNPLNYTHLG 2368
Query: 474 EII---DGV--DMRAEVGILTRNIVIQGE---------------------VEDSCYAENQ 507
+ DG + RAEVGILTRNI+I+G +C
Sbjct: 2369 ITVTLPDGTLFEARAEVGILTRNILIRGSDNVEWNNKIPACPDGFDTGEFATQTCLQGKF 2428
Query: 508 CQFFDYDTFGGHIMIMK-----NFTSVHLSYVELKHMGQQ-QMGRYPVHFHLCGDVDYKG 561
+ D FGG +M N + + YVE+ H GQ ++GRYP+H+HL GD+ +K
Sbjct: 2429 GEEIGSDQFGGCVMFHAPVPGANMVTGRIEYVEVFHAGQAFRLGRYPIHWHLLGDLQFK- 2487
Query: 562 GYRHATFVDGLSIHHSFSRCITVHGTNGLLIKDTIGFDTLGHCFFLEDGIEQRNTLFHNL 621
++V G +IH +++R +T+H T+ LL++ I +D G FF+EDGIE N L +NL
Sbjct: 2488 -----SYVRGCAIHQAYNRAVTIHNTHHLLVERNIIYDIKGGAFFIEDGIEHGNILQYNL 2542
Query: 622 GLLTKPGTLLPTDRNNSMCTTMRDKVFGNYIPVPATDCMAVSTFWIAHPNNNLINNAAAG 681
+ + T L D + + FW+ +PNN + +NA AG
Sbjct: 2543 AVFVQQSTSL------------------------LNDDVTPAAFWVTNPNNTIRHNAVAG 2578
Query: 682 SQDAGIWYLFHKEPTGESSGLQLLAKPELTPLGIFYNNRVHSNFKAGLFI 731
G WY + P G S + K PLG F+NN VHS G++I
Sbjct: 2579 GTHFGFWYRMNNHPDGPSYDRNICQK--RVPLGEFFNNTVHSQGWFGMWI 2626
Score = 72.0 bits (175), Expect = 4e-12
Identities = 59/206 (28%), Positives = 94/206 (45%), Gaps = 32/206 (15%)
Query: 415 GVKLNLLDDVSSWKPGDQIVVASTDYSMYQAEEFTLLPCSECSHFQVKVKETPQFLHMGE 474
G K+ L D W+ G++IV+ +T Y +Q E +++ H + + ++ + H E
Sbjct: 3179 GSKVLSLMDAVDWQEGEEIVITTTSYDFHQTETRSIVKILH-DHKILILNDSLSYTHFAE 3237
Query: 475 II------DGVDMRAEVGILTRNIVIQGEVEDSCYAENQCQFFDYDTFGGHIMI------ 522
+ + A+VGIL+RNI I GE + D+FG +++
Sbjct: 3238 KYHVPGTGESYTLAADVGILSRNIKIVGEDYPG---------WSEDSFGARVLVGSFTEN 3288
Query: 523 MKNFT-SVHLSYVELKHMGQQQMG-----RYPVHFHLCGDVDYKGGYRHATFVDGLSIHH 576
M F + +S VE H GQ+ RY V F G + G ++++ G + HH
Sbjct: 3289 MMTFKGNARISNVEFYHSGQEGFRDSTDPRYAVTFLNLGQIQEHG----SSYIRGCAFHH 3344
Query: 577 SFSRCITVHGTNGLLIKDTIGFDTLG 602
FS I V GT+GL I D I T+G
Sbjct: 3345 GFSPAIGVFGTDGLDIDDNIIHFTVG 3370
Score = 63.5 bits (153), Expect = 1e-09
Identities = 42/115 (36%), Positives = 60/115 (52%), Gaps = 8/115 (6%)
Query: 133 VVIKEGDMLRLTSDATVHSIVIQDGGLLVFGDNKDGSRNITLRTHYILIQDGGALHIGAE 192
VVI +G + L + +++ GG L+F + +I L+ ILI DGG L IG E
Sbjct: 2198 VVITKGQTILLDQSTPILKMLLIQGGTLIFDE-----ADIELQAENILITDGGVLQIGTE 2252
Query: 193 KCRYKSKATITLYGKSDEGESMPTFGKKFIGVEAGGTLELHGAR-KASWTLLART 246
++ KA ITL+G E +P +G K + V G L+LHG +WT LA T
Sbjct: 2253 TSPFQHKAVITLHGHLRSPE-LPVYGAKTLAVRE-GILDLHGVPVPVTWTRLAHT 2305
Score = 35.8 bits (81), Expect = 0.29
Identities = 27/116 (23%), Positives = 53/116 (45%), Gaps = 12/116 (10%)
Query: 972 LIRHPSCVNVSKWNAVICSGT-YAQVYVQTWS----TQNLS-MTITRDEY------PSNP 1019
+IR +C + +W + C G YA + +++ T+ LS + I + Y P +
Sbjct: 3744 IIRDSTCKYLPEWQSYQCFGMEYAMMVIESLDPDTETRRLSPVAIMGNGYVDLINGPQDH 3803
Query: 1020 MVLRGINQKAAFPQYQPVVMLEKGYTIHWNGPAPRTTFLYLVNFNKNDWIRVGLCY 1075
G + + +V L K Y +++ G +P+ L L+N + N + VG+ +
Sbjct: 3804 GWCAGYTCQRRLSLFHSIVALNKSYEVYFTGTSPQNLRLMLLNVDHNKAVLVGIFF 3859
>gi|126131104 fibrocystin isoform 2 [Homo sapiens]
Length = 3396
Score = 66.2 bits (160), Expect = 2e-10
Identities = 101/415 (24%), Positives = 160/415 (38%), Gaps = 126/415 (30%)
Query: 411 EVVDGVKLNLLDDVSSWKPGDQIVVASTDYSMYQAEEFTLLPCSECSHFQVKVKETPQFL 470
++ G + +++D W+P D+IV++S+ Y ++AE T+ E V++ E +
Sbjct: 2874 DIASGNERIIVEDAVDWRPHDKIVLSSSSYEPHEAEVLTV---KEVKGHHVRIYERLKHR 2930
Query: 471 HMGEI---IDG--VDMRAEVGILTRNIVIQGEVEDSCYAENQCQFF---DYDTFGGHIMI 522
H+G + DG + + AEVG+LTRNI IQ +V SC F + F G + +
Sbjct: 2931 HIGSVHVTEDGRHIRLAAEVGLLTRNIQIQPDV--SCRGRLFVGSFRKSSREEFSGVLQL 2988
Query: 523 MKNFTSVHLSYVELKHMGQQQMGRYPVHFHLCGDVDYKGGYRHATFVDGLSIHHSFSRCI 582
+ VE+++ G L V++ +++ ++H S I
Sbjct: 2989 LN---------VEIQNFGSP----------LYSSVEF-SNVSAGSWIISSTLHQSCGGGI 3028
Query: 583 TVHGTNGLLIKDTIGFDTLGHCFFLEDGIEQRNTLFHNL-GLLTKPGTLLPTDRNNSMCT 641
++G+L+ D I F T GH LE Q T+ +NL L+T+P
Sbjct: 3029 HAAASHGVLLNDNIVFGTAGHGIDLEG---QAYTVTNNLVVLMTQP-------------- 3071
Query: 642 TMRDKVFGNYIPVPATDCMAVSTFWIAH------PNNNLINNAAAGSQDAGIWYLFHKEP 695
A ST W+A + NL N AGS+ G HK
Sbjct: 3072 -------------------AWSTIWVAGIKVNQVKDINLHGNVVAGSERLGFHIRGHK-- 3110
Query: 696 TGESSGLQLLAKPELTPLGIFYNNRVHSNFKA-GLFIDKGVKTTNSSAADPREYLCLDNS 754
S +LL + +N HS+ L+ + G LDN
Sbjct: 3111 ---CSSCELL----------WSDNVAHSSLHGLHLYKESG----------------LDNC 3141
Query: 755 ARFRPHQDANPEKPRVAALIDRLIAFKNNDNGAWVR-GGDIIVQNSAFADNGIGL 808
R I +AFKN D GA + + ++N DN IGL
Sbjct: 3142 TR-----------------ISGFLAFKNFDYGAMLHVENSVEIENITLVDNTIGL 3179
Score = 65.5 bits (158), Expect = 3e-10
Identities = 42/119 (35%), Positives = 63/119 (52%), Gaps = 8/119 (6%)
Query: 119 RLRNWDPGQ--DSAKQVVIKEGDMLRLTSDATVHSIVIQDGGLLVFGDNKDGSRNITLRT 176
R +W P + V ++ G +L L ++ ++ +++ GG L+F I LR
Sbjct: 1930 RTHSWFPERLPQDGDNVTVENGQLLLLDTNTSILNLLHIKGGKLIFM----APGPIELRA 1985
Query: 177 HYILIQDGGALHIGAEKCRYKSKATITLYGKSDEGESMPTFGKKFIGVEAGGTLELHGA 235
H IL+ DGG L IG+E ++ +A ITLYG S P +G KF+ V GTL LHG+
Sbjct: 1986 HAILVSDGGELRIGSEDKPFQGRAQITLYGSSYSTPFFP-YGVKFLAVR-NGTLSLHGS 2042
Score = 56.2 bits (134), Expect = 2e-07
Identities = 80/338 (23%), Positives = 138/338 (40%), Gaps = 53/338 (15%)
Query: 421 LDDVSSWKPGDQIVVASTD--YSMYQAEEFTLLPCSECSHFQVK--VKETPQFLHMGEII 476
L+D W PGD++V+ S EE + + + +K ++ + F
Sbjct: 2064 LEDAVDWNPGDEVVIISGTGVKGAKPMEEIVTVETVQDTDLYLKSPLRYSHNFTENWVAG 2123
Query: 477 DGVDMRAEVGILTRNIVIQGEVED-------SCYAEN-------QCQFFDYDTFGGHI-- 520
+ ++A V +L+R+I IQG + + SC N C + + G
Sbjct: 2124 EHHILKATVALLSRSITIQGNLTNEREKLLVSCQEANAPEGNLQHCLYSMSEKMLGSRDM 2183
Query: 521 ---MIMKNFTSVHLSYVELKHMGQQQMGRYPVHFHLCGDVDYKGGYRHATFVDGLSIHHS 577
+I+++F S V+LK + Q +G+ H HL + G R + F+ G ++ +S
Sbjct: 2184 GARVIVQSFPE-EPSQVQLKGVQFQVLGQ-AFHKHL-SSLTLVGAMRES-FIQGCTVRNS 2239
Query: 578 FSRCITVHGTNGLLIKDTIGFDTLGHCFFLEDGIEQR----NTLFHNLGLLTKPGTLLPT 633
FSR +++ GT GL + + ++ LGH + E R + + G ++
Sbjct: 2240 FSRGLSMCGTLGLKVDSNVFYNILGHALLVGTCTEMRYISWEAIHGRKDDWSGHGNII-- 2297
Query: 634 DRNNSMCTTMRDKVFGNYIPVPATDCMAVSTFWIAHPNNNLINNAAAGSQDAGIWYLFHK 693
RNN + + N + + S +I P N + N G AG Y FH
Sbjct: 2298 -RNNVIIQVSGAEGLSN------PEMLTPSGIYICSPTNVIEGNRVCG---AGYGYFFHL 2347
Query: 694 EPTGESSGLQLLAKPELTPLGIFYNNRVHSNFKAGLFI 731
T ++S LL+ F N HS + GLF+
Sbjct: 2348 -MTNQTSQAPLLS---------FTQNIAHSCTRYGLFV 2375
>gi|126131102 fibrocystin isoform 1 [Homo sapiens]
Length = 4074
Score = 66.2 bits (160), Expect = 2e-10
Identities = 101/415 (24%), Positives = 160/415 (38%), Gaps = 126/415 (30%)
Query: 411 EVVDGVKLNLLDDVSSWKPGDQIVVASTDYSMYQAEEFTLLPCSECSHFQVKVKETPQFL 470
++ G + +++D W+P D+IV++S+ Y ++AE T+ E V++ E +
Sbjct: 2874 DIASGNERIIVEDAVDWRPHDKIVLSSSSYEPHEAEVLTV---KEVKGHHVRIYERLKHR 2930
Query: 471 HMGEI---IDG--VDMRAEVGILTRNIVIQGEVEDSCYAENQCQFF---DYDTFGGHIMI 522
H+G + DG + + AEVG+LTRNI IQ +V SC F + F G + +
Sbjct: 2931 HIGSVHVTEDGRHIRLAAEVGLLTRNIQIQPDV--SCRGRLFVGSFRKSSREEFSGVLQL 2988
Query: 523 MKNFTSVHLSYVELKHMGQQQMGRYPVHFHLCGDVDYKGGYRHATFVDGLSIHHSFSRCI 582
+ VE+++ G L V++ +++ ++H S I
Sbjct: 2989 LN---------VEIQNFGSP----------LYSSVEF-SNVSAGSWIISSTLHQSCGGGI 3028
Query: 583 TVHGTNGLLIKDTIGFDTLGHCFFLEDGIEQRNTLFHNL-GLLTKPGTLLPTDRNNSMCT 641
++G+L+ D I F T GH LE Q T+ +NL L+T+P
Sbjct: 3029 HAAASHGVLLNDNIVFGTAGHGIDLEG---QAYTVTNNLVVLMTQP-------------- 3071
Query: 642 TMRDKVFGNYIPVPATDCMAVSTFWIAH------PNNNLINNAAAGSQDAGIWYLFHKEP 695
A ST W+A + NL N AGS+ G HK
Sbjct: 3072 -------------------AWSTIWVAGIKVNQVKDINLHGNVVAGSERLGFHIRGHK-- 3110
Query: 696 TGESSGLQLLAKPELTPLGIFYNNRVHSNFKA-GLFIDKGVKTTNSSAADPREYLCLDNS 754
S +LL + +N HS+ L+ + G LDN
Sbjct: 3111 ---CSSCELL----------WSDNVAHSSLHGLHLYKESG----------------LDNC 3141
Query: 755 ARFRPHQDANPEKPRVAALIDRLIAFKNNDNGAWVR-GGDIIVQNSAFADNGIGL 808
R I +AFKN D GA + + ++N DN IGL
Sbjct: 3142 TR-----------------ISGFLAFKNFDYGAMLHVENSVEIENITLVDNTIGL 3179
Score = 65.5 bits (158), Expect = 3e-10
Identities = 42/119 (35%), Positives = 63/119 (52%), Gaps = 8/119 (6%)
Query: 119 RLRNWDPGQ--DSAKQVVIKEGDMLRLTSDATVHSIVIQDGGLLVFGDNKDGSRNITLRT 176
R +W P + V ++ G +L L ++ ++ +++ GG L+F I LR
Sbjct: 1930 RTHSWFPERLPQDGDNVTVENGQLLLLDTNTSILNLLHIKGGKLIFM----APGPIELRA 1985
Query: 177 HYILIQDGGALHIGAEKCRYKSKATITLYGKSDEGESMPTFGKKFIGVEAGGTLELHGA 235
H IL+ DGG L IG+E ++ +A ITLYG S P +G KF+ V GTL LHG+
Sbjct: 1986 HAILVSDGGELRIGSEDKPFQGRAQITLYGSSYSTPFFP-YGVKFLAVR-NGTLSLHGS 2042
Score = 56.2 bits (134), Expect = 2e-07
Identities = 80/338 (23%), Positives = 138/338 (40%), Gaps = 53/338 (15%)
Query: 421 LDDVSSWKPGDQIVVASTD--YSMYQAEEFTLLPCSECSHFQVK--VKETPQFLHMGEII 476
L+D W PGD++V+ S EE + + + +K ++ + F
Sbjct: 2064 LEDAVDWNPGDEVVIISGTGVKGAKPMEEIVTVETVQDTDLYLKSPLRYSHNFTENWVAG 2123
Query: 477 DGVDMRAEVGILTRNIVIQGEVED-------SCYAEN-------QCQFFDYDTFGGHI-- 520
+ ++A V +L+R+I IQG + + SC N C + + G
Sbjct: 2124 EHHILKATVALLSRSITIQGNLTNEREKLLVSCQEANAPEGNLQHCLYSMSEKMLGSRDM 2183
Query: 521 ---MIMKNFTSVHLSYVELKHMGQQQMGRYPVHFHLCGDVDYKGGYRHATFVDGLSIHHS 577
+I+++F S V+LK + Q +G+ H HL + G R + F+ G ++ +S
Sbjct: 2184 GARVIVQSFPE-EPSQVQLKGVQFQVLGQ-AFHKHL-SSLTLVGAMRES-FIQGCTVRNS 2239
Query: 578 FSRCITVHGTNGLLIKDTIGFDTLGHCFFLEDGIEQR----NTLFHNLGLLTKPGTLLPT 633
FSR +++ GT GL + + ++ LGH + E R + + G ++
Sbjct: 2240 FSRGLSMCGTLGLKVDSNVFYNILGHALLVGTCTEMRYISWEAIHGRKDDWSGHGNII-- 2297
Query: 634 DRNNSMCTTMRDKVFGNYIPVPATDCMAVSTFWIAHPNNNLINNAAAGSQDAGIWYLFHK 693
RNN + + N + + S +I P N + N G AG Y FH
Sbjct: 2298 -RNNVIIQVSGAEGLSN------PEMLTPSGIYICSPTNVIEGNRVCG---AGYGYFFHL 2347
Query: 694 EPTGESSGLQLLAKPELTPLGIFYNNRVHSNFKAGLFI 731
T ++S LL+ F N HS + GLF+
Sbjct: 2348 -MTNQTSQAPLLS---------FTQNIAHSCTRYGLFV 2375
>gi|210147552 O-linked mannose
beta1,2-N-acetylglucosaminyltransferase [Homo sapiens]
Length = 660
Score = 49.3 bits (116), Expect = 3e-05
Identities = 29/92 (31%), Positives = 48/92 (52%), Gaps = 2/92 (2%)
Query: 261 KDFSRGLNVRVIDQDTAKILESERFDTHEYRNESRRLQEFLRFQDPGRIVAIAVGDSAAK 320
++ RG++V V++Q T ++ FDT+ +E + FL PGR++ V D +
Sbjct: 125 REQGRGIHVIVLNQATGHVMAKRVFDTYS-PHEDEAMVLFLNMVAPGRVLICTVKDEGSF 183
Query: 321 SLLQGTIQMIQERLGSELIQGLGYRQAWALVG 352
L + T + + LGS+ LG+R WA VG
Sbjct: 184 HL-KDTAKALLRSLGSQAGPALGWRDTWAFVG 214
>gi|20270363 family with sequence similarity 3, member D [Homo
sapiens]
Length = 224
Score = 43.5 bits (101), Expect = 0.001
Identities = 25/96 (26%), Positives = 47/96 (48%), Gaps = 3/96 (3%)
Query: 260 EKDFSRGLNVRVIDQDTAKILESERFDTHEYRNESRRLQEFLRFQDPGRIVAIAVGDSAA 319
+ + RGLN+ +++ T +L + FD Y + L +FL+ G +V +A D
Sbjct: 94 KNNVGRGLNIALVNGTTGAVLGQKAFDM--YSGDVMHLVKFLKEIPGGALVLVASYDDPG 151
Query: 320 KSLLQGTIQMIQERLGSELIQGLGYRQAWALVGVID 355
+ + ++ + LGS + LG+R +W +G D
Sbjct: 152 TKMNDESRKLFSD-LGSSYAKQLGFRDSWVFIGAKD 186
>gi|13324682 family 3, member A protein [Homo sapiens]
Length = 230
Score = 42.4 bits (98), Expect = 0.003
Identities = 25/88 (28%), Positives = 47/88 (53%), Gaps = 3/88 (3%)
Query: 265 RGLNVRVIDQDTAKILESERFDTHEYRNESRRLQEFLRFQDPGRIVAIAVGDSAAKSLLQ 324
RGLN+ +++ + +++E+ FD + + L +F+R G +V +A D A + +
Sbjct: 103 RGLNIALVNGVSGELIEARAFDM--WAGDVNDLLKFIRPLHEGTLVFVASYDDPATKMNE 160
Query: 325 GTIQMIQERLGSELIQGLGYRQAWALVG 352
T ++ E LGS + L +R +W VG
Sbjct: 161 ETRKLFSE-LGSRNAKELAFRDSWVFVG 187
>gi|91807125 family with sequence similarity 3, member C precursor
[Homo sapiens]
Length = 227
Score = 41.6 bits (96), Expect = 0.005
Identities = 27/93 (29%), Positives = 45/93 (48%), Gaps = 3/93 (3%)
Query: 260 EKDFSRGLNVRVIDQDTAKILESERFDTHEYRNESRRLQEFLRFQDPGRIVAIAVGDSAA 319
+ + RG+NV + + T ++L+++ FD + + EFL+ G IV + D A
Sbjct: 97 KNNVGRGINVALANGKTGEVLDTKYFDM--WGGDVAPFIEFLKAIQDGTIVLMGTYDDGA 154
Query: 320 KSLLQGTIQMIQERLGSELIQGLGYRQAWALVG 352
L ++I + LGS I LG+R W G
Sbjct: 155 TKLNDEARRLIAD-LGSTSITNLGFRDNWVFCG 186
>gi|7661714 family with sequence similarity 3, member C precursor
[Homo sapiens]
Length = 227
Score = 41.6 bits (96), Expect = 0.005
Identities = 27/93 (29%), Positives = 45/93 (48%), Gaps = 3/93 (3%)
Query: 260 EKDFSRGLNVRVIDQDTAKILESERFDTHEYRNESRRLQEFLRFQDPGRIVAIAVGDSAA 319
+ + RG+NV + + T ++L+++ FD + + EFL+ G IV + D A
Sbjct: 97 KNNVGRGINVALANGKTGEVLDTKYFDM--WGGDVAPFIEFLKAIQDGTIVLMGTYDDGA 154
Query: 320 KSLLQGTIQMIQERLGSELIQGLGYRQAWALVG 352
L ++I + LGS I LG+R W G
Sbjct: 155 TKLNDEARRLIAD-LGSTSITNLGFRDNWVFCG 186
>gi|46255032 family with sequence similarity 3, member B isoform b
[Homo sapiens]
Length = 187
Score = 37.4 bits (85), Expect = 0.10
Identities = 27/109 (24%), Positives = 51/109 (46%), Gaps = 4/109 (3%)
Query: 264 SRGLNVRVIDQDTAKILESERFDTHEYRNESRRLQEFLRFQDPGRIVAIAVGDSAAKSLL 323
+RG+N+ +++ T + + FD +E N S + +F++ P ++ + D + L
Sbjct: 58 ARGINIAIVNYVTGNVTATRCFDMYEGDN-SGPMTKFIQSAAPKSLLFMVTYDDGSTRLN 116
Query: 324 QGTIQMIQERLGSELIQGLGYRQAWALVGVIDGGSTSCNESVRNYENHS 372
I E LGS+ I+ + +R +W + G +E R NHS
Sbjct: 117 NDAKNAI-EALGSKEIRNMKFRSSWVFIAA--KGLELPSEIQREKINHS 162
>gi|46255030 family with sequence similarity 3, member B isoform a
[Homo sapiens]
Length = 235
Score = 37.4 bits (85), Expect = 0.10
Identities = 27/109 (24%), Positives = 51/109 (46%), Gaps = 4/109 (3%)
Query: 264 SRGLNVRVIDQDTAKILESERFDTHEYRNESRRLQEFLRFQDPGRIVAIAVGDSAAKSLL 323
+RG+N+ +++ T + + FD +E N S + +F++ P ++ + D + L
Sbjct: 106 ARGINIAIVNYVTGNVTATRCFDMYEGDN-SGPMTKFIQSAAPKSLLFMVTYDDGSTRLN 164
Query: 324 QGTIQMIQERLGSELIQGLGYRQAWALVGVIDGGSTSCNESVRNYENHS 372
I E LGS+ I+ + +R +W + G +E R NHS
Sbjct: 165 NDAKNAI-EALGSKEIRNMKFRSSWVFIAA--KGLELPSEIQREKINHS 210
>gi|29294649 dicer1 [Homo sapiens]
Length = 1922
Score = 32.3 bits (72), Expect = 3.2
Identities = 34/132 (25%), Positives = 45/132 (34%), Gaps = 18/132 (13%)
Query: 1219 DKAETQRGDPSVISVNGTDFTFRSAGVLLLVVDP-------------CSVPFRLTEKTVF 1265
+K+E + G PS T F F+ V+ P V LT + F
Sbjct: 901 EKSEARIGIPSTKYTKETPFVFKLEDYQDAVIIPRYRNFDQPHRFYVADVYTDLTPLSKF 960
Query: 1266 PLADVSRIEEYLKTGIPPRSIVLLSTRGEIKQLNISHLLVPLGLAKPAHLYDKGSTIFLG 1325
P + EY KT L T L++ H L L P HL KG + L
Sbjct: 961 PSPEYETFAEYYKT-----KYNLDLTNLNQPLLDVDHTSSRLNLLTPRHLNQKGKALPLS 1015
Query: 1326 FSGNFKPSWTKL 1337
+ K W L
Sbjct: 1016 SAEKRKAKWESL 1027
>gi|29294651 dicer1 [Homo sapiens]
Length = 1922
Score = 32.3 bits (72), Expect = 3.2
Identities = 34/132 (25%), Positives = 45/132 (34%), Gaps = 18/132 (13%)
Query: 1219 DKAETQRGDPSVISVNGTDFTFRSAGVLLLVVDP-------------CSVPFRLTEKTVF 1265
+K+E + G PS T F F+ V+ P V LT + F
Sbjct: 901 EKSEARIGIPSTKYTKETPFVFKLEDYQDAVIIPRYRNFDQPHRFYVADVYTDLTPLSKF 960
Query: 1266 PLADVSRIEEYLKTGIPPRSIVLLSTRGEIKQLNISHLLVPLGLAKPAHLYDKGSTIFLG 1325
P + EY KT L T L++ H L L P HL KG + L
Sbjct: 961 PSPEYETFAEYYKT-----KYNLDLTNLNQPLLDVDHTSSRLNLLTPRHLNQKGKALPLS 1015
Query: 1326 FSGNFKPSWTKL 1337
+ K W L
Sbjct: 1016 SAEKRKAKWESL 1027
>gi|78042577 MAP7 domain containing 1 [Homo sapiens]
Length = 841
Score = 32.0 bits (71), Expect = 4.2
Identities = 24/88 (27%), Positives = 36/88 (40%), Gaps = 13/88 (14%)
Query: 6 SRGHSPAFLQPQNGNSRHPSGYVPGKVVPLRPPPPPKSQASA-----KFTSIRREDRATF 60
SRG +P + P++ S VP PP K + K RRE+RA +
Sbjct: 93 SRGPTPPAMGPRDARPPRRSSQPSPTAVPASDSPPTKQEVKKAGERHKLAKERREERAKY 152
Query: 61 AFS--------PEEQQAQRESQKQKRHK 80
+ E+ +A RE Q Q+R +
Sbjct: 153 LAAKKAVWLEKEEKAKALREKQLQERRR 180
>gi|94400925 synaptonemal complex protein 2-like [Homo sapiens]
Length = 812
Score = 31.6 bits (70), Expect = 5.5
Identities = 45/193 (23%), Positives = 74/193 (38%), Gaps = 29/193 (15%)
Query: 238 ASWTLLARTLNSSGLPFGSYTFEKDFSRGLNVRVI-----------DQDTAKILESERFD 286
+S + L+ T N SY+ K N+R++ ++D AK+L +
Sbjct: 512 SSTSELSWTSNQKKKSLKSYSSRKKTRTRSNLRILPVFPPSSGSGHEKDQAKLLSPSEKE 571
Query: 287 THEYRNESRRLQEFLRFQDPGRIVAIAVGDSAAKSLLQGTIQMIQERLGSELIQGLGYRQ 346
E N + +FQD + DSA K+ LQ + + + L + +
Sbjct: 572 IPEQNNTTSPKTSEQKFQDS--FAFLTAEDSAQKTELQDPHSLSE-------LSSLKHSE 622
Query: 347 AWALVGVIDGGS----TSCNESVRNYENHS--SGGKALAQR---EFYTVDGQKFSVTAYS 397
+++ S TS +RN E+ G A +Q+ E G FS+T
Sbjct: 623 DEEKPKIVNQESLTESTSLKHKLRNLEDKDIPEGSFAKSQQSRLEEEVASGSPFSITEER 682
Query: 398 EWIEGVSLSGFRV 410
E EG+S S V
Sbjct: 683 ELPEGISTSSLEV 695
>gi|37537554 hypothetical protein FLJ37538 [Homo sapiens]
Length = 841
Score = 31.6 bits (70), Expect = 5.5
Identities = 18/71 (25%), Positives = 30/71 (42%), Gaps = 5/71 (7%)
Query: 20 NSRHPSGYVPGKVVPLR-----PPPPPKSQASAKFTSIRREDRATFAFSPEEQQAQRESQ 74
+S+ P+G P VP R PPPPP A+ R+ P + Q +
Sbjct: 362 HSKEPAGSTPAPQVPARERETPPPPPPPPAANLLLLGPSGRARSHSTPLPPQGSGQPRGE 421
Query: 75 KQKRHKNTFIC 85
++ + ++ IC
Sbjct: 422 RELPNSHSMIC 432
>gi|62422571 collapsin response mediator protein 1 isoform 1 [Homo
sapiens]
Length = 686
Score = 31.2 bits (69), Expect = 7.2
Identities = 20/76 (26%), Positives = 33/76 (43%), Gaps = 4/76 (5%)
Query: 826 VSESLFVGESRNYGFQGGQNKYVGTGGIDQK--PRTLPRNRTFPIRGFQ--IYDGPIHLT 881
+S+ V E N G +++ + R RN+ F ++G +YDGP++
Sbjct: 561 ISQGKIVFEDGNINVNKGMGRFIPRKAFPEHLYQRVKIRNKVFGLQGVSRGMYDGPVYEV 620
Query: 882 RSTFKKYVPTPDRYSS 897
+T K P P SS
Sbjct: 621 PATPKYATPAPSAKSS 636
>gi|4503051 collapsin response mediator protein 1 isoform 2 [Homo
sapiens]
Length = 572
Score = 31.2 bits (69), Expect = 7.2
Identities = 20/76 (26%), Positives = 33/76 (43%), Gaps = 4/76 (5%)
Query: 826 VSESLFVGESRNYGFQGGQNKYVGTGGIDQK--PRTLPRNRTFPIRGFQ--IYDGPIHLT 881
+S+ V E N G +++ + R RN+ F ++G +YDGP++
Sbjct: 447 ISQGKIVFEDGNINVNKGMGRFIPRKAFPEHLYQRVKIRNKVFGLQGVSRGMYDGPVYEV 506
Query: 882 RSTFKKYVPTPDRYSS 897
+T K P P SS
Sbjct: 507 PATPKYATPAPSAKSS 522
>gi|21493039 A-kinase anchor protein 4 isoform 2 [Homo sapiens]
Length = 845
Score = 30.8 bits (68), Expect = 9.4
Identities = 23/90 (25%), Positives = 40/90 (44%), Gaps = 11/90 (12%)
Query: 316 DSAAKSLLQGTIQMIQERL-----GSELIQG------LGYRQAWALVGVIDGGSTSCNES 364
DS AK L+ +++IQ L G + + +GY GG ++ S
Sbjct: 529 DSLAKDLIVSALKLIQYHLTQQTKGKDTCEEDCPGSTMGYMAQSTQYEKCGGGQSAKALS 588
Query: 365 VRNYENHSSGGKALAQREFYTVDGQKFSVT 394
V+ E+H + G + Q+E +D QK ++
Sbjct: 589 VKQLESHRAPGPSTCQKENQHLDSQKMDMS 618
>gi|21493037 A-kinase anchor protein 4 isoform 1 [Homo sapiens]
Length = 854
Score = 30.8 bits (68), Expect = 9.4
Identities = 23/90 (25%), Positives = 40/90 (44%), Gaps = 11/90 (12%)
Query: 316 DSAAKSLLQGTIQMIQERL-----GSELIQG------LGYRQAWALVGVIDGGSTSCNES 364
DS AK L+ +++IQ L G + + +GY GG ++ S
Sbjct: 538 DSLAKDLIVSALKLIQYHLTQQTKGKDTCEEDCPGSTMGYMAQSTQYEKCGGGQSAKALS 597
Query: 365 VRNYENHSSGGKALAQREFYTVDGQKFSVT 394
V+ E+H + G + Q+E +D QK ++
Sbjct: 598 VKQLESHRAPGPSTCQKENQHLDSQKMDMS 627
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.136 0.414
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 55,443,663
Number of Sequences: 37866
Number of extensions: 2629473
Number of successful extensions: 7273
Number of sequences better than 10.0: 22
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 16
Number of HSP's that attempted gapping in prelim test: 7206
Number of HSP's gapped (non-prelim): 44
length of query: 1383
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1268
effective length of database: 13,892,928
effective search space: 17616232704
effective search space used: 17616232704
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.