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Search of human proteins with 13899299
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|13899299 sestrin 2 [Homo sapiens]
(480 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|13899299 sestrin 2 [Homo sapiens] 983 0.0
gi|7657437 sestrin 1 [Homo sapiens] 528 e-150
gi|31377591 sestrin 3 [Homo sapiens] 518 e-147
gi|27437042 colony stimulating factor 3 receptor isoform b precu... 34 0.26
gi|122937267 lemur tyrosine kinase 3 [Homo sapiens] 34 0.26
gi|21040251 actin-binding Rho activating protein [Homo sapiens] 34 0.26
gi|38026934 Rho guanine nucleotide exchange factor (GEF) 11 isof... 34 0.34
gi|7662086 Rho guanine nucleotide exchange factor (GEF) 11 isofo... 34 0.34
gi|254039650 synaptotagmin-like 5 isoform 1 [Homo sapiens] 34 0.34
gi|254039648 synaptotagmin-like 5 isoform 2 [Homo sapiens] 34 0.34
gi|20270305 synaptotagmin-like 5 isoform 1 [Homo sapiens] 34 0.34
gi|112734870 hypothetical protein LOC57648 [Homo sapiens] 33 0.57
gi|112799847 cardiac muscle ryanodine receptor [Homo sapiens] 33 0.75
gi|116517292 cut-like 2 [Homo sapiens] 33 0.75
gi|238859651 pleckstrin homology domain containing family A memb... 32 0.98
gi|225690497 tight junction associated protein 1 isoform b [Homo... 32 0.98
gi|225690495 tight junction associated protein 1 isoform b [Homo... 32 0.98
gi|225690493 tight junction associated protein 1 isoform b [Homo... 32 0.98
gi|225690491 tight junction associated protein 1 isoform b [Homo... 32 0.98
gi|225690489 tight junction associated protein 1 isoform a [Homo... 32 0.98
gi|225690487 tight junction associated protein 1 isoform a [Homo... 32 0.98
gi|239755004 PREDICTED: hypothetical protein [Homo sapiens] 32 1.3
gi|239749560 PREDICTED: hypothetical protein XP_002347086 [Homo ... 32 1.3
gi|239743710 PREDICTED: hypothetical protein XP_002342931 [Homo ... 32 1.3
gi|20070163 voltage-dependent calcium channel alpha 1G subunit i... 32 1.7
gi|169215927 PREDICTED: hypothetical protein [Homo sapiens] 32 1.7
gi|239752137 PREDICTED: hypothetical protein [Homo sapiens] 32 1.7
gi|169215514 PREDICTED: hypothetical protein [Homo sapiens] 32 1.7
gi|169215483 PREDICTED: hypothetical protein isoform 2 [Homo sap... 32 1.7
gi|14043024 BCL2-associated athanogene 3 [Homo sapiens] 32 1.7
>gi|13899299 sestrin 2 [Homo sapiens]
Length = 480
Score = 983 bits (2542), Expect = 0.0
Identities = 480/480 (100%), Positives = 480/480 (100%)
Query: 1 MIVADSECRAELKDYLRFAPGGVGDSGPGEEQRESRARRGPRGPSAFIPVEEVLREGAES 60
MIVADSECRAELKDYLRFAPGGVGDSGPGEEQRESRARRGPRGPSAFIPVEEVLREGAES
Sbjct: 1 MIVADSECRAELKDYLRFAPGGVGDSGPGEEQRESRARRGPRGPSAFIPVEEVLREGAES 60
Query: 61 LEQHLGLEALMSSGRVDNLAVVMGLHPDYFTSFWRLHYLLLHTDGPLASSWRHYIAIMAA 120
LEQHLGLEALMSSGRVDNLAVVMGLHPDYFTSFWRLHYLLLHTDGPLASSWRHYIAIMAA
Sbjct: 61 LEQHLGLEALMSSGRVDNLAVVMGLHPDYFTSFWRLHYLLLHTDGPLASSWRHYIAIMAA 120
Query: 121 ARHQCSYLVGSHMAEFLQTGGDPEWLLGLHRAPEKLRKLSEINKLLAHRPWLITKEHIQA 180
ARHQCSYLVGSHMAEFLQTGGDPEWLLGLHRAPEKLRKLSEINKLLAHRPWLITKEHIQA
Sbjct: 121 ARHQCSYLVGSHMAEFLQTGGDPEWLLGLHRAPEKLRKLSEINKLLAHRPWLITKEHIQA 180
Query: 181 LLKTGEHTWSLAELIQALVLLTHCHSLSSFVFGCGILPEGDADGSPAPQAPTPPSEQSSP 240
LLKTGEHTWSLAELIQALVLLTHCHSLSSFVFGCGILPEGDADGSPAPQAPTPPSEQSSP
Sbjct: 181 LLKTGEHTWSLAELIQALVLLTHCHSLSSFVFGCGILPEGDADGSPAPQAPTPPSEQSSP 240
Query: 241 PSRDPLNNSGGFESARDVEALMERMQQLQESLLRDEGTSQEEMESRFELEKSESLLVTPS 300
PSRDPLNNSGGFESARDVEALMERMQQLQESLLRDEGTSQEEMESRFELEKSESLLVTPS
Sbjct: 241 PSRDPLNNSGGFESARDVEALMERMQQLQESLLRDEGTSQEEMESRFELEKSESLLVTPS 300
Query: 301 ADILEPSPHPDMLCFVEDPTFGYEDFTRRGAQAPPTFRAQDYTWEDHGYSLIQRLYPEGG 360
ADILEPSPHPDMLCFVEDPTFGYEDFTRRGAQAPPTFRAQDYTWEDHGYSLIQRLYPEGG
Sbjct: 301 ADILEPSPHPDMLCFVEDPTFGYEDFTRRGAQAPPTFRAQDYTWEDHGYSLIQRLYPEGG 360
Query: 361 QLLDEKFQAAYSLTYNTIAMHSGVDTSVLRRAIWNYIHCVFGIRYDDYDYGEVNQLLERN 420
QLLDEKFQAAYSLTYNTIAMHSGVDTSVLRRAIWNYIHCVFGIRYDDYDYGEVNQLLERN
Sbjct: 361 QLLDEKFQAAYSLTYNTIAMHSGVDTSVLRRAIWNYIHCVFGIRYDDYDYGEVNQLLERN 420
Query: 421 LKVYIKTVACYPEKTTRRMYNLFWRHFRHSEKVHVNLLLLEARMQAALLYALRAITRYMT 480
LKVYIKTVACYPEKTTRRMYNLFWRHFRHSEKVHVNLLLLEARMQAALLYALRAITRYMT
Sbjct: 421 LKVYIKTVACYPEKTTRRMYNLFWRHFRHSEKVHVNLLLLEARMQAALLYALRAITRYMT 480
>gi|7657437 sestrin 1 [Homo sapiens]
Length = 551
Score = 528 bits (1361), Expect = e-150
Identities = 268/450 (59%), Positives = 330/450 (73%), Gaps = 14/450 (3%)
Query: 42 RGPSAFIPVEEVLREGAESLEQH-LGLEALMSSGRVDNLAVVMGLHPDYFTSFWRLHYLL 100
+GPS FIP +E+L+ G+E + H L ++ + GR+DN+ +VM HP Y SF + + L
Sbjct: 105 QGPSRFIPEKEILQVGSEDAQMHALFADSFAALGRLDNITLVMVFHPQYLESFLKTQHYL 164
Query: 101 LHTDGPLASSWRHYIAIMAAARHQCSYLVGSHMAEFLQTGGDPEWLLGLHRAPEKLRKLS 160
L DGPL +RHYI IMAAARHQCSYLV H+ +FL GGDP+WL GL AP+KL+ L
Sbjct: 165 LQMDGPLPLHYRHYIGIMAAARHQCSYLVNLHVNDFLHVGGDPKWLNGLENAPQKLQNLG 224
Query: 161 EINKLLAHRPWLITKEHIQALLKTGEHTWSLAELIQALVLLTHCHSLSSFVFGCGILPEG 220
E+NK+LAHRPWLITKEHI+ LLK EH+WSLAEL+ A+VLLTH HSL+SF FGCGI PE
Sbjct: 225 ELNKVLAHRPWLITKEHIEGLLKAEEHSWSLAELVHAVVLLTHYHSLASFTFGCGISPEI 284
Query: 221 DADGSPAPQAPTPPS-------EQSSPPSRDPLNNSGGF---ESARDVEALMERMQQLQE 270
DG + P+ + + P+N++ +S +VEALME+M+QLQE
Sbjct: 285 HCDGGHTFRPPSVSNYCICDITNGNHSVDEMPVNSAENVSVSDSFFEVEALMEKMRQLQE 344
Query: 271 SLLRDEGTSQEEMESRFELEKSESLLVTPSADILEPSPHPDMLCFVEDPTFGYEDFTRRG 330
+E SQEEM SRFE+EK ES+ V S+D E +P + ED ++GY+DF+R G
Sbjct: 345 CRDEEEA-SQEEMASRFEIEKRESMFVF-SSDDEEVTPARAVSRHFEDTSYGYKDFSRHG 402
Query: 331 AQAPPTFRAQDYTWEDHGYSLIQRLYPEGGQLLDEKFQAAYSLTYNTIAMHSGVDTSVLR 390
P TFR QDY WEDHGYSL+ RLYP+ GQL+DEKF AY+LTYNT+AMH VDTS+LR
Sbjct: 403 MHVP-TFRVQDYCWEDHGYSLVNRLYPDVGQLIDEKFHIAYNLTYNTMAMHKDVDTSMLR 461
Query: 391 RAIWNYIHCVFGIRYDDYDYGEVNQLLERNLKVYIKTVACYPEKTTRRMYNLFWRHFRHS 450
RAIWNYIHC+FGIRYDDYDYGE+NQLL+R+ KVYIKTV C PEK T+RMY+ FWR F+HS
Sbjct: 462 RAIWNYIHCMFGIRYDDYDYGEINQLLDRSFKVYIKTVVCTPEKVTKRMYDSFWRQFKHS 521
Query: 451 EKVHVNLLLLEARMQAALLYALRAITRYMT 480
EKVHVNLLL+EARMQA LLYALRAITRYMT
Sbjct: 522 EKVHVNLLLIEARMQAELLYALRAITRYMT 551
>gi|31377591 sestrin 3 [Homo sapiens]
Length = 492
Score = 518 bits (1333), Expect = e-147
Identities = 265/457 (57%), Positives = 329/457 (71%), Gaps = 20/457 (4%)
Query: 42 RGPSAFIPVEEVLREGAESLEQHLGLEALMSSGRVDNLAVVMGLHPDYFTSFWRLHYLLL 101
RGPSAFIP +EV++ + +E +SGR+DN+ VM LH Y SF R + +L
Sbjct: 38 RGPSAFIPEKEVVQANTVDERTNFLVEEYSTSGRLDNITQVMSLHTQYLESFLRSQFYML 97
Query: 102 HTDGPLASSWRHYIAIMAAARHQCSYLVGSHMAEFLQTGGDPEWLLGLHRAPEKLRKLSE 161
DGPL +RHYIAIMAAARHQCSYL+ H+ EFL+TGG EWL GL P++L+ L+E
Sbjct: 98 RMDGPLPLPYRHYIAIMAAARHQCSYLINMHVDEFLKTGGIAEWLNGLEYVPQRLKNLNE 157
Query: 162 INKLLAHRPWLITKEHIQALLKTGEHTWSLAELIQALVLLTHCHSLSSFVFGCGILPEGD 221
INKLLAHRPWLITKEHIQ L+KTGE+ WSL EL+ A+VLL H H+L+SFVFG GI PE D
Sbjct: 158 INKLLAHRPWLITKEHIQKLVKTGENNWSLPELVHAVVLLAHYHALASFVFGSGINPERD 217
Query: 222 ADGSPAPQAPTP--------PSEQSSPPSRDPLNNSGGFESARDVEALMERMQQLQESLL 273
+ S + + ++ + + +N G +S ++EALMERM++LQE
Sbjct: 218 PEISNGFRLISVNNFCVCDLANDNNIENASLSGSNFGIVDSLSELEALMERMKRLQEE-R 276
Query: 274 RDEGTSQEEMESRFELEKSESLLVTPSADILEPSPH----------PDMLCFVEDPTFGY 323
DE SQEEM +RFE EK ESL V S D PH D+ ++EDP FGY
Sbjct: 277 EDEEASQEEMSTRFEKEKKESLFVV-SGDTFHSFPHSDFEDDMIITSDVSRYIEDPGFGY 335
Query: 324 EDFTRRGAQAPPTFRAQDYTWEDHGYSLIQRLYPEGGQLLDEKFQAAYSLTYNTIAMHSG 383
EDF RRG + PTFRAQDYTWE+HG+SL+ RLY + G LLDEKF+ Y+LTYNT+A H
Sbjct: 336 EDFARRGEEHLPTFRAQDYTWENHGFSLVNRLYSDIGHLLDEKFRMVYNLTYNTMATHED 395
Query: 384 VDTSVLRRAIWNYIHCVFGIRYDDYDYGEVNQLLERNLKVYIKTVACYPEKTTRRMYNLF 443
VDT++LRRA++NY+HC+FGIRYDDYDYGEVNQLLER+LKVYIKTV CYPE+TT+RMY+ +
Sbjct: 396 VDTTMLRRALFNYVHCMFGIRYDDYDYGEVNQLLERSLKVYIKTVTCYPERTTKRMYDSY 455
Query: 444 WRHFRHSEKVHVNLLLLEARMQAALLYALRAITRYMT 480
WR F+HSEKVHVNLLL+EARMQA LLYALRAITR++T
Sbjct: 456 WRQFKHSEKVHVNLLLMEARMQAELLYALRAITRHLT 492
>gi|27437042 colony stimulating factor 3 receptor isoform b
precursor [Homo sapiens]
Length = 769
Score = 34.3 bits (77), Expect = 0.26
Identities = 14/45 (31%), Positives = 24/45 (53%)
Query: 206 SLSSFVFGCGILPEGDADGSPAPQAPTPPSEQSSPPSRDPLNNSG 250
++ SF+ C P+ G+ + P PS ++SPP+ P+ SG
Sbjct: 716 AIRSFMGSCWAAPQAQGQGTISAVTPLSPSWRASPPAPSPMRTSG 760
>gi|122937267 lemur tyrosine kinase 3 [Homo sapiens]
Length = 1489
Score = 34.3 bits (77), Expect = 0.26
Identities = 21/47 (44%), Positives = 24/47 (51%), Gaps = 4/47 (8%)
Query: 218 PEGDADGSPAPQAPTPPSEQSSPPSRDPLNNS---GGFESARDVEAL 261
PEGD D S P PTPP ++P P N+S G FE A D L
Sbjct: 1406 PEGDTDPSTPPAPPTPP-HPATPGDGFPSNDSGFGGSFEWAEDFPLL 1451
>gi|21040251 actin-binding Rho activating protein [Homo sapiens]
Length = 381
Score = 34.3 bits (77), Expect = 0.26
Identities = 40/151 (26%), Positives = 61/151 (40%), Gaps = 20/151 (13%)
Query: 215 GILPEGDADGSPAPQAPTPPSE----QSSP--PSRDPLNNSGGFESARDVEALMERMQQL 268
G LP G D AP+ TPP+ QS+P P R P + G S + E + +++
Sbjct: 50 GWLPGGTQDSPQAPKPITPPTSHQKAQSAPKSPPRLPEGHGDGQSSEKAPEVSHIKKKEV 109
Query: 269 QESLLR---DEGTSQEEMESRFELEKSESLLVTPSADI-----LEPSPHPDMLC--FVED 318
++++ + G + R+E + P DI SP C V +
Sbjct: 110 SKTVVSKTYERGGDVSHLSHRYERDAGVLEPGQPENDIDRILHSHGSPTRRRKCANLVSE 169
Query: 319 PTFGYEDFTRRGAQAPPTFRAQDYTWEDHGY 349
T G+ R Q PT+R+ ED GY
Sbjct: 170 LTKGW----RVMEQEEPTWRSDSVDTEDSGY 196
>gi|38026934 Rho guanine nucleotide exchange factor (GEF) 11 isoform 2
[Homo sapiens]
Length = 1562
Score = 33.9 bits (76), Expect = 0.34
Identities = 22/66 (33%), Positives = 33/66 (50%), Gaps = 9/66 (13%)
Query: 226 PAPQAPTPPSEQSSPPSRDPLNNSGGFESARDVEAL------MERMQQLQESLLRD---E 276
P P P P++Q PSR L++S F + E L +R+Q + LL D E
Sbjct: 1134 PPPPGPREPAQQGPTPSRVELDDSDVFHGEPEPEELPGGTGSQQRVQGKHQVLLEDPEQE 1193
Query: 277 GTSQEE 282
G+++EE
Sbjct: 1194 GSAEEE 1199
>gi|7662086 Rho guanine nucleotide exchange factor (GEF) 11 isoform 1
[Homo sapiens]
Length = 1522
Score = 33.9 bits (76), Expect = 0.34
Identities = 22/66 (33%), Positives = 33/66 (50%), Gaps = 9/66 (13%)
Query: 226 PAPQAPTPPSEQSSPPSRDPLNNSGGFESARDVEAL------MERMQQLQESLLRD---E 276
P P P P++Q PSR L++S F + E L +R+Q + LL D E
Sbjct: 1094 PPPPGPREPAQQGPTPSRVELDDSDVFHGEPEPEELPGGTGSQQRVQGKHQVLLEDPEQE 1153
Query: 277 GTSQEE 282
G+++EE
Sbjct: 1154 GSAEEE 1159
Score = 30.0 bits (66), Expect = 4.9
Identities = 21/71 (29%), Positives = 33/71 (46%), Gaps = 4/71 (5%)
Query: 225 SPAPQAPTPPSEQSSPPS--RDPLNNSGGFESARDVEALMERMQQLQESLLRDEGTSQEE 282
SP P P PP ++ + P +DP + R++ L + ++LQ+ L TSQ
Sbjct: 150 SPPPPPPLPPPQRITGPKPLQDPEVQKHATQILRNM--LRQEEKELQDILPLYGDTSQRP 207
Query: 283 MESRFELEKSE 293
E R L+ E
Sbjct: 208 SEGRLSLDSQE 218
>gi|254039650 synaptotagmin-like 5 isoform 1 [Homo sapiens]
Length = 730
Score = 33.9 bits (76), Expect = 0.34
Identities = 28/93 (30%), Positives = 42/93 (45%), Gaps = 21/93 (22%)
Query: 223 DGSPAPQAP--------TPPSEQSSPPSR----DPLNNSGGFESARDVEALMERMQQLQE 270
D P P+ P TP ++ S PS ++ GFE++ D+ A+ Q+L +
Sbjct: 240 DQEPGPRTPKSSRSNGVTPGTQSSPAPSTRTVTSVISREYGFENSMDLAAIEGTSQELTK 299
Query: 271 SLLRD---------EGTSQEEMESRFELEKSES 294
S R+ GTS +SR EL+ SES
Sbjct: 300 SHRRNTSGTPSIAVSGTSLSSDQSRSELDLSES 332
>gi|254039648 synaptotagmin-like 5 isoform 2 [Homo sapiens]
Length = 752
Score = 33.9 bits (76), Expect = 0.34
Identities = 28/93 (30%), Positives = 42/93 (45%), Gaps = 21/93 (22%)
Query: 223 DGSPAPQAP--------TPPSEQSSPPSR----DPLNNSGGFESARDVEALMERMQQLQE 270
D P P+ P TP ++ S PS ++ GFE++ D+ A+ Q+L +
Sbjct: 240 DQEPGPRTPKSSRSNGVTPGTQSSPAPSTRTVTSVISREYGFENSMDLAAIEGTSQELTK 299
Query: 271 SLLRD---------EGTSQEEMESRFELEKSES 294
S R+ GTS +SR EL+ SES
Sbjct: 300 SHRRNTSGTPSIAVSGTSLSSDQSRSELDLSES 332
>gi|20270305 synaptotagmin-like 5 isoform 1 [Homo sapiens]
Length = 730
Score = 33.9 bits (76), Expect = 0.34
Identities = 28/93 (30%), Positives = 42/93 (45%), Gaps = 21/93 (22%)
Query: 223 DGSPAPQAP--------TPPSEQSSPPSR----DPLNNSGGFESARDVEALMERMQQLQE 270
D P P+ P TP ++ S PS ++ GFE++ D+ A+ Q+L +
Sbjct: 240 DQEPGPRTPKSSRSNGVTPGTQSSPAPSTRTVTSVISREYGFENSMDLAAIEGTSQELTK 299
Query: 271 SLLRD---------EGTSQEEMESRFELEKSES 294
S R+ GTS +SR EL+ SES
Sbjct: 300 SHRRNTSGTPSIAVSGTSLSSDQSRSELDLSES 332
>gi|112734870 hypothetical protein LOC57648 [Homo sapiens]
Length = 1094
Score = 33.1 bits (74), Expect = 0.57
Identities = 25/75 (33%), Positives = 31/75 (41%), Gaps = 5/75 (6%)
Query: 208 SSFVFGCGILPEGDADGSPAPQAPTP----PSEQSSPPSRDPLN-NSGGFESARDVEALM 262
SS I P G D PAP AP P P + P ++P+ + GG DV A +
Sbjct: 819 SSSATALQIQPPGSPDPPPAPPAPAPASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPL 878
Query: 263 ERMQQLQESLLRDEG 277
LQ LR G
Sbjct: 879 VTPSLLQMVRLRSVG 893
>gi|112799847 cardiac muscle ryanodine receptor [Homo sapiens]
Length = 4967
Score = 32.7 bits (73), Expect = 0.75
Identities = 30/112 (26%), Positives = 50/112 (44%), Gaps = 17/112 (15%)
Query: 30 EEQRESRARRGPRGPSAFIPVEEV------LREGAESLEQHLGLEALMSSGRVDNLAVVM 83
E ++E +GPR AF + V LR +L + L L++L + V
Sbjct: 4220 ESEKERPEEQGPR--MAFFSILTVRSALFALRYNILTLMRMLSLKSLKKQMKKVKKMTVK 4277
Query: 84 GLHPDYFTSFWRLHYLLLHTDGPLASSWRHYIAIMAAARHQCSYLVGSHMAE 135
+ +F+S+W + LLH +AS +R + I+ CS L+G + E
Sbjct: 4278 DMVTAFFSSYWSIFMTLLHF---VASVFRGFFRII------CSLLLGGSLVE 4320
>gi|116517292 cut-like 2 [Homo sapiens]
Length = 1486
Score = 32.7 bits (73), Expect = 0.75
Identities = 21/86 (24%), Positives = 40/86 (46%), Gaps = 8/86 (9%)
Query: 213 GCGILPEGDADGSPAPQAPTPPSEQSSPPSRDPLNNSGGFESA-----RDVEALMERMQQ 267
G GILP G + P PQ+P +E P ++ G E++ +D + + +Q
Sbjct: 1243 GPGILPPGHSHPDPTPQSPDSETEDQKPTVKELELQEGPEENSTPLTTQDKAQVRIKQEQ 1302
Query: 268 LQESLLRDEGTSQEEMESRFELEKSE 293
++E + G+ ++ EL+K +
Sbjct: 1303 MEEDAEEEAGSQPQDSG---ELDKGQ 1325
>gi|238859651 pleckstrin homology domain containing family A member
4 isoform 1 [Homo sapiens]
Length = 779
Score = 32.3 bits (72), Expect = 0.98
Identities = 21/61 (34%), Positives = 30/61 (49%), Gaps = 5/61 (8%)
Query: 23 VGDSGPGEEQRESRARRGPRGPSAFIPVEEVLREGAESLEQHLGLEA-----LMSSGRVD 77
VG SG + R S + PR + ++P E RE SL Q L EA +M+ G +D
Sbjct: 638 VGHSGAQKWLRSSGSWSSPRNTTPYLPTSEGHRERVLSLSQALATEASQWHRMMTGGNLD 697
Query: 78 N 78
+
Sbjct: 698 S 698
Score = 31.6 bits (70), Expect = 1.7
Identities = 14/34 (41%), Positives = 19/34 (55%), Gaps = 4/34 (11%)
Query: 221 DADGSPAPQAPTPPS----EQSSPPSRDPLNNSG 250
D+ G P P P PPS +++ PP P+ NSG
Sbjct: 697 DSQGDPLPGVPLPPSDPTRQETPPPRSPPVANSG 730
>gi|225690497 tight junction associated protein 1 isoform b [Homo
sapiens]
Length = 547
Score = 32.3 bits (72), Expect = 0.98
Identities = 22/70 (31%), Positives = 30/70 (42%), Gaps = 3/70 (4%)
Query: 201 LTHCHSLSSFVFGCGILPEGDADGSPAPQAPTPPSEQSSP---PSRDPLNNSGGFESARD 257
L +C + ++ EG P+P TP S Q+SP PS PL S SA
Sbjct: 337 LPNCTYATRQAISLSLVEEGSERARPSPVPSTPASAQASPHHQPSPAPLTLSAPASSASS 396
Query: 258 VEALMERMQQ 267
E L+ Q+
Sbjct: 397 EEDLLVSWQR 406
>gi|225690495 tight junction associated protein 1 isoform b [Homo
sapiens]
Length = 547
Score = 32.3 bits (72), Expect = 0.98
Identities = 22/70 (31%), Positives = 30/70 (42%), Gaps = 3/70 (4%)
Query: 201 LTHCHSLSSFVFGCGILPEGDADGSPAPQAPTPPSEQSSP---PSRDPLNNSGGFESARD 257
L +C + ++ EG P+P TP S Q+SP PS PL S SA
Sbjct: 337 LPNCTYATRQAISLSLVEEGSERARPSPVPSTPASAQASPHHQPSPAPLTLSAPASSASS 396
Query: 258 VEALMERMQQ 267
E L+ Q+
Sbjct: 397 EEDLLVSWQR 406
>gi|225690493 tight junction associated protein 1 isoform b [Homo
sapiens]
Length = 547
Score = 32.3 bits (72), Expect = 0.98
Identities = 22/70 (31%), Positives = 30/70 (42%), Gaps = 3/70 (4%)
Query: 201 LTHCHSLSSFVFGCGILPEGDADGSPAPQAPTPPSEQSSP---PSRDPLNNSGGFESARD 257
L +C + ++ EG P+P TP S Q+SP PS PL S SA
Sbjct: 337 LPNCTYATRQAISLSLVEEGSERARPSPVPSTPASAQASPHHQPSPAPLTLSAPASSASS 396
Query: 258 VEALMERMQQ 267
E L+ Q+
Sbjct: 397 EEDLLVSWQR 406
>gi|225690491 tight junction associated protein 1 isoform b [Homo
sapiens]
Length = 547
Score = 32.3 bits (72), Expect = 0.98
Identities = 22/70 (31%), Positives = 30/70 (42%), Gaps = 3/70 (4%)
Query: 201 LTHCHSLSSFVFGCGILPEGDADGSPAPQAPTPPSEQSSP---PSRDPLNNSGGFESARD 257
L +C + ++ EG P+P TP S Q+SP PS PL S SA
Sbjct: 337 LPNCTYATRQAISLSLVEEGSERARPSPVPSTPASAQASPHHQPSPAPLTLSAPASSASS 396
Query: 258 VEALMERMQQ 267
E L+ Q+
Sbjct: 397 EEDLLVSWQR 406
>gi|225690489 tight junction associated protein 1 isoform a [Homo
sapiens]
Length = 557
Score = 32.3 bits (72), Expect = 0.98
Identities = 22/70 (31%), Positives = 30/70 (42%), Gaps = 3/70 (4%)
Query: 201 LTHCHSLSSFVFGCGILPEGDADGSPAPQAPTPPSEQSSP---PSRDPLNNSGGFESARD 257
L +C + ++ EG P+P TP S Q+SP PS PL S SA
Sbjct: 347 LPNCTYATRQAISLSLVEEGSERARPSPVPSTPASAQASPHHQPSPAPLTLSAPASSASS 406
Query: 258 VEALMERMQQ 267
E L+ Q+
Sbjct: 407 EEDLLVSWQR 416
>gi|225690487 tight junction associated protein 1 isoform a [Homo
sapiens]
Length = 557
Score = 32.3 bits (72), Expect = 0.98
Identities = 22/70 (31%), Positives = 30/70 (42%), Gaps = 3/70 (4%)
Query: 201 LTHCHSLSSFVFGCGILPEGDADGSPAPQAPTPPSEQSSP---PSRDPLNNSGGFESARD 257
L +C + ++ EG P+P TP S Q+SP PS PL S SA
Sbjct: 347 LPNCTYATRQAISLSLVEEGSERARPSPVPSTPASAQASPHHQPSPAPLTLSAPASSASS 406
Query: 258 VEALMERMQQ 267
E L+ Q+
Sbjct: 407 EEDLLVSWQR 416
>gi|239755004 PREDICTED: hypothetical protein [Homo sapiens]
Length = 558
Score = 32.0 bits (71), Expect = 1.3
Identities = 18/47 (38%), Positives = 25/47 (53%)
Query: 29 GEEQRESRARRGPRGPSAFIPVEEVLREGAESLEQHLGLEALMSSGR 75
G+ + +S+ +RGPR P A P+ R G L + G EAL S R
Sbjct: 389 GQHRCDSQEQRGPRPPPAHGPLHPGGRPGTAQLRREPGPEALRSRPR 435
>gi|239749560 PREDICTED: hypothetical protein XP_002347086 [Homo
sapiens]
Length = 443
Score = 32.0 bits (71), Expect = 1.3
Identities = 18/47 (38%), Positives = 25/47 (53%)
Query: 29 GEEQRESRARRGPRGPSAFIPVEEVLREGAESLEQHLGLEALMSSGR 75
G+ + +S+ +RGPR P A P+ R G L + G EAL S R
Sbjct: 353 GQHRCDSQEQRGPRPPPAHGPLHPGGRPGTAQLRREPGPEALRSRPR 399
>gi|239743710 PREDICTED: hypothetical protein XP_002342931 [Homo
sapiens]
Length = 522
Score = 32.0 bits (71), Expect = 1.3
Identities = 18/47 (38%), Positives = 25/47 (53%)
Query: 29 GEEQRESRARRGPRGPSAFIPVEEVLREGAESLEQHLGLEALMSSGR 75
G+ + +S+ +RGPR P A P+ R G L + G EAL S R
Sbjct: 353 GQHRCDSQEQRGPRPPPAHGPLHPGGRPGTAQLRREPGPEALRSRPR 399
>gi|20070163 voltage-dependent calcium channel alpha 1G subunit
isoform 1 [Homo sapiens]
Length = 2377
Score = 31.6 bits (70), Expect = 1.7
Identities = 35/133 (26%), Positives = 54/133 (40%), Gaps = 22/133 (16%)
Query: 180 ALLKTGEHTWSLAELIQALVLLTHCHSLS-----SFVFGCGILP-------EGDADGSPA 227
AL+ GEH L+ L++ T +S S G + P G A+ A
Sbjct: 1021 ALVSLGEHPELRKSLLPPLIIHTAATPMSLPKSTSTGLGEALGPASRRTSSSGSAEPGAA 1080
Query: 228 PQAPTPPSEQSSPPSRDPLNNSGGFESARDVEALMERMQQL--------QESLLRDEGTS 279
+ +PPS +SSP S P + + + S R + R L + SLL EG
Sbjct: 1081 HEMKSPPSARSSPHS--PWSAASSWTSRRSSRNSLGRAPSLKRRSPSGERRSLLSGEGQE 1138
Query: 280 QEEMESRFELEKS 292
++ E E E++
Sbjct: 1139 SQDEEESSEEERA 1151
>gi|169215927 PREDICTED: hypothetical protein [Homo sapiens]
Length = 357
Score = 31.6 bits (70), Expect = 1.7
Identities = 19/68 (27%), Positives = 32/68 (47%)
Query: 224 GSPAPQAPTPPSEQSSPPSRDPLNNSGGFESARDVEALMERMQQLQESLLRDEGTSQEEM 283
G P P P+ +S PP P + G R + ++ M QE LL+ + +++
Sbjct: 7 GLPLPPIVIQPARRSLPPIVTPASRRLGPRGGRHLGSVSTAMAATQELLLQLQKDNRDGR 66
Query: 284 ESRFELEK 291
+ + ELEK
Sbjct: 67 QRKQELEK 74
>gi|239752137 PREDICTED: hypothetical protein [Homo sapiens]
Length = 357
Score = 31.6 bits (70), Expect = 1.7
Identities = 19/68 (27%), Positives = 32/68 (47%)
Query: 224 GSPAPQAPTPPSEQSSPPSRDPLNNSGGFESARDVEALMERMQQLQESLLRDEGTSQEEM 283
G P P P+ +S PP P + G R + ++ M QE LL+ + +++
Sbjct: 7 GLPLPPIVIQPARRSLPPIVTPASRRLGPRGGRHLGSVSTAMAATQELLLQLQKDNRDGR 66
Query: 284 ESRFELEK 291
+ + ELEK
Sbjct: 67 QRKQELEK 74
>gi|169215514 PREDICTED: hypothetical protein [Homo sapiens]
Length = 357
Score = 31.6 bits (70), Expect = 1.7
Identities = 19/68 (27%), Positives = 32/68 (47%)
Query: 224 GSPAPQAPTPPSEQSSPPSRDPLNNSGGFESARDVEALMERMQQLQESLLRDEGTSQEEM 283
G P P P+ +S PP P + G R + ++ M QE LL+ + +++
Sbjct: 7 GLPLPPIVIQPARRSLPPIVTPASRRLGPRGGRHLGSVSTAMAATQELLLQLQKDNRDGR 66
Query: 284 ESRFELEK 291
+ + ELEK
Sbjct: 67 QRKQELEK 74
>gi|169215483 PREDICTED: hypothetical protein isoform 2 [Homo
sapiens]
Length = 356
Score = 31.6 bits (70), Expect = 1.7
Identities = 19/68 (27%), Positives = 32/68 (47%)
Query: 224 GSPAPQAPTPPSEQSSPPSRDPLNNSGGFESARDVEALMERMQQLQESLLRDEGTSQEEM 283
G P P P+ +S PP P + G R + ++ M QE LL+ + +++
Sbjct: 7 GLPLPPIVIQPARRSLPPIVTPASRRLGPRGGRHLGSVSTAMAATQELLLQLQKDNRDGR 66
Query: 284 ESRFELEK 291
+ + ELEK
Sbjct: 67 QRKQELEK 74
>gi|14043024 BCL2-associated athanogene 3 [Homo sapiens]
Length = 575
Score = 31.6 bits (70), Expect = 1.7
Identities = 20/78 (25%), Positives = 34/78 (43%), Gaps = 9/78 (11%)
Query: 225 SPAPQAPTPPSEQSSPPSRDPLNNSGGFESARDVEALMERMQQLQESLLRDEGTSQEEME 284
+PA P P E +PP VEA++E++Q L++++ EG ++
Sbjct: 401 APAEATPPKPGEAEAPPKH---------PGVLKVEAILEKVQGLEQAVDNFEGKKTDKKY 451
Query: 285 SRFELEKSESLLVTPSAD 302
E ++ LL S D
Sbjct: 452 LMIEEYLTKELLALDSVD 469
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.136 0.415
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,437,390
Number of Sequences: 37866
Number of extensions: 1020981
Number of successful extensions: 6938
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 27
Number of HSP's successfully gapped in prelim test: 82
Number of HSP's that attempted gapping in prelim test: 6760
Number of HSP's gapped (non-prelim): 246
length of query: 480
length of database: 18,247,518
effective HSP length: 106
effective length of query: 374
effective length of database: 14,233,722
effective search space: 5323412028
effective search space used: 5323412028
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.