Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 13899233
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|13899233 tetratricopeptide repeat domain 25 [Homo sapiens]
(672 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|13899233 tetratricopeptide repeat domain 25 [Homo sapiens] 1335 0.0
gi|5803181 stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizi... 58 2e-08
gi|224028289 tetratricopeptide repeat domain 28 [Homo sapiens] 57 6e-08
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 55 2e-07
gi|164519122 LGN protein [Homo sapiens] 54 4e-07
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 50 5e-06
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 50 5e-06
gi|41322919 plectin 1 isoform 8 [Homo sapiens] 50 5e-06
gi|41322910 plectin 1 isoform 7 [Homo sapiens] 50 5e-06
gi|41322916 plectin 1 isoform 6 [Homo sapiens] 50 5e-06
gi|41322908 plectin 1 isoform 3 [Homo sapiens] 50 5e-06
gi|41322912 plectin 1 isoform 2 [Homo sapiens] 50 5e-06
gi|47607492 plectin 1 isoform 1 [Homo sapiens] 50 5e-06
gi|224548927 G-protein signaling modulator 1 (AGS3-like, C. eleg... 49 2e-05
gi|224548925 G-protein signaling modulator 1 (AGS3-like, C. eleg... 49 2e-05
gi|16262452 cingulin [Homo sapiens] 49 2e-05
gi|156104908 myosin heavy chain 6 [Homo sapiens] 48 3e-05
gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens] 46 1e-04
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo... 46 1e-04
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 46 1e-04
gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens] 45 2e-04
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s... 45 2e-04
gi|89179321 smooth muscle cell associated protein-1 isoform 3 [H... 45 2e-04
gi|29725607 smooth muscle cell associated protein-1 isoform 2 [H... 45 2e-04
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 44 5e-04
gi|221219020 NYD-SP11 protein [Homo sapiens] 44 6e-04
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [... 44 6e-04
gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo ... 44 6e-04
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 43 8e-04
gi|4506921 small glutamine-rich tetratricopeptide [Homo sapiens] 43 8e-04
>gi|13899233 tetratricopeptide repeat domain 25 [Homo sapiens]
Length = 672
Score = 1335 bits (3455), Expect = 0.0
Identities = 672/672 (100%), Positives = 672/672 (100%)
Query: 1 MSDPEGETLRSTFPSYMAEGERLYLCGEFSKAAQSFSNALYLQDGDKNCLVARSKCFLKM 60
MSDPEGETLRSTFPSYMAEGERLYLCGEFSKAAQSFSNALYLQDGDKNCLVARSKCFLKM
Sbjct: 1 MSDPEGETLRSTFPSYMAEGERLYLCGEFSKAAQSFSNALYLQDGDKNCLVARSKCFLKM 60
Query: 61 GDLERSLKDAEASLQSDPAFCKGILQKAETLYTMGDFEFALVFYHRGYKLRPDREFRVGI 120
GDLERSLKDAEASLQSDPAFCKGILQKAETLYTMGDFEFALVFYHRGYKLRPDREFRVGI
Sbjct: 61 GDLERSLKDAEASLQSDPAFCKGILQKAETLYTMGDFEFALVFYHRGYKLRPDREFRVGI 120
Query: 121 QKAQEAINNSVGSPSSIKLENKGDLSFLSKQAENIKAQQKPQPMKHLLHPTKGEPKWKAS 180
QKAQEAINNSVGSPSSIKLENKGDLSFLSKQAENIKAQQKPQPMKHLLHPTKGEPKWKAS
Sbjct: 121 QKAQEAINNSVGSPSSIKLENKGDLSFLSKQAENIKAQQKPQPMKHLLHPTKGEPKWKAS 180
Query: 181 LKSEKTVRQLLGELYVDKEYLEKLLLDEDLIKGTMKGGLTVEDLIMTGINYLDTHSNFWR 240
LKSEKTVRQLLGELYVDKEYLEKLLLDEDLIKGTMKGGLTVEDLIMTGINYLDTHSNFWR
Sbjct: 181 LKSEKTVRQLLGELYVDKEYLEKLLLDEDLIKGTMKGGLTVEDLIMTGINYLDTHSNFWR 240
Query: 241 QQKPIYARERDRKLMQEKWLRDHKRRPSQTAHYILKSLEDIDMLLTSGSAEGSLQKAEKV 300
QQKPIYARERDRKLMQEKWLRDHKRRPSQTAHYILKSLEDIDMLLTSGSAEGSLQKAEKV
Sbjct: 241 QQKPIYARERDRKLMQEKWLRDHKRRPSQTAHYILKSLEDIDMLLTSGSAEGSLQKAEKV 300
Query: 301 LKKVLEWNKEEVPNKDELVGNLYSCIGNAQIELGQMEAALQSHRKDLEIAKEYDLPDAKS 360
LKKVLEWNKEEVPNKDELVGNLYSCIGNAQIELGQMEAALQSHRKDLEIAKEYDLPDAKS
Sbjct: 301 LKKVLEWNKEEVPNKDELVGNLYSCIGNAQIELGQMEAALQSHRKDLEIAKEYDLPDAKS 360
Query: 361 RALDNIGRVFARVGKFQQAIDTWEEKIPLAKTTLEKTWLFHEIGRCYLELDQAWQAQNYG 420
RALDNIGRVFARVGKFQQAIDTWEEKIPLAKTTLEKTWLFHEIGRCYLELDQAWQAQNYG
Sbjct: 361 RALDNIGRVFARVGKFQQAIDTWEEKIPLAKTTLEKTWLFHEIGRCYLELDQAWQAQNYG 420
Query: 421 EKSQQCAEEEGDIEWQLNASVLVAQAQVKLRDFESAVNNFEKALERAKLVHNNEAQQAII 480
EKSQQCAEEEGDIEWQLNASVLVAQAQVKLRDFESAVNNFEKALERAKLVHNNEAQQAII
Sbjct: 421 EKSQQCAEEEGDIEWQLNASVLVAQAQVKLRDFESAVNNFEKALERAKLVHNNEAQQAII 480
Query: 481 SALDDANKGIIRELRKTNYVENLKEKSEGEASLYEDRIITREKDMRRVRDEPEKVVKQWD 540
SALDDANKGIIRELRKTNYVENLKEKSEGEASLYEDRIITREKDMRRVRDEPEKVVKQWD
Sbjct: 481 SALDDANKGIIRELRKTNYVENLKEKSEGEASLYEDRIITREKDMRRVRDEPEKVVKQWD 540
Query: 541 HSEDEKETDEDDEAFGEALQSPASGKQSVEAGKARSDLGAVAKGLSGELGTRSGETGRKL 600
HSEDEKETDEDDEAFGEALQSPASGKQSVEAGKARSDLGAVAKGLSGELGTRSGETGRKL
Sbjct: 541 HSEDEKETDEDDEAFGEALQSPASGKQSVEAGKARSDLGAVAKGLSGELGTRSGETGRKL 600
Query: 601 LEAGRRESREIYRRPSGELEQRLSGEFSRQEPEELKKLSEVGRREPEELGKTQFGEIGET 660
LEAGRRESREIYRRPSGELEQRLSGEFSRQEPEELKKLSEVGRREPEELGKTQFGEIGET
Sbjct: 601 LEAGRRESREIYRRPSGELEQRLSGEFSRQEPEELKKLSEVGRREPEELGKTQFGEIGET 660
Query: 661 KKTGNEMEKEYE 672
KKTGNEMEKEYE
Sbjct: 661 KKTGNEMEKEYE 672
>gi|5803181 stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizing
protein) [Homo sapiens]
Length = 543
Score = 58.2 bits (139), Expect = 2e-08
Identities = 42/160 (26%), Positives = 73/160 (45%), Gaps = 8/160 (5%)
Query: 19 EGERLYLCGEFSKAAQSFSNALYLQDGDKNCLVARSKCFLKMGDLERSLKDAEASLQSDP 78
+G + G++ +A + ++ A+ D R+ C+ K+ + + +LKD E +Q +P
Sbjct: 366 KGNECFQKGDYPQAMKHYTEAIKRNPKDAKLYSNRAACYTKLLEFQLALKDCEECIQLEP 425
Query: 79 AFCKGILQKAETLYTMGDFEFALVFYHRGYKLRPD-REFRVGIQKAQEAINNSVGSPSSI 137
F KG +KA L M D+ A+ Y + L +E G Q+ A N SP +
Sbjct: 426 TFIKGYTRKAAALEAMKDYTKAMDVYQKALDLDSSCKEAADGYQRCMMAQYNRHDSPEDV 485
Query: 138 KLENKGD---LSFLSKQAENI---KAQQKPQPM-KHLLHP 170
K D +S A + + Q+ PQ + +HL +P
Sbjct: 486 KRRAMADPEVQQIMSDPAMRLILEQMQKDPQALSEHLKNP 525
>gi|224028289 tetratricopeptide repeat domain 28 [Homo sapiens]
Length = 2481
Score = 57.0 bits (136), Expect = 6e-08
Identities = 39/144 (27%), Positives = 75/144 (52%), Gaps = 7/144 (4%)
Query: 292 GSLQKAEKVLKKVLEWNKEEVPNKDELVGNLYSC-IGNAQIELGQMEAALQSHRKDLEIA 350
G+ ++A L++ L ++ KD + + +C +G ++G+ + ALQ H+ DL+IA
Sbjct: 971 GNYEQAISCLERQLNIARDM---KDRALESDAACGLGGVYQQMGEYDTALQYHQLDLQIA 1027
Query: 351 KEYDLPDAKSRALDNIGRVFARVGKFQQAIDTWEEKIPLA---KTTLEKTWLFHEIGRCY 407
+E + P + RA N+G + +G F++A+ E+ + +A KT + +GR +
Sbjct: 1028 EETNNPTCQGRAYGNLGLTYESLGTFERAVVYQEQHLSIAAQMNDLAAKTVSYSSLGRTH 1087
Query: 408 LELDQAWQAQNYGEKSQQCAEEEG 431
L QA Y ++ + AE+ G
Sbjct: 1088 HALQNYSQAVMYLQEGLRLAEQLG 1111
Score = 50.4 bits (119), Expect = 5e-06
Identities = 48/192 (25%), Positives = 84/192 (43%), Gaps = 6/192 (3%)
Query: 326 IGNAQIELGQMEAALQSHRKDLEIAKEYDLPDAKSRALDNIGRVFARVGKFQQAIDTWEE 385
+G+A G AL +HR L +A + +A S AL ++G V+ +G + A+ + ++
Sbjct: 280 LGSAFFSKGNYREALTNHRHQLVLAMKLKDREAASSALSSLGHVYTAIGDYPNALASHKQ 339
Query: 386 KIPLAKTTLEKTWLFHEIGRCYLELDQAWQAQNYGEKSQQCAEEEGDIEWQLNASVLVAQ 445
+ LAK + ++ E+G + + A E + QC E+ I L A+
Sbjct: 340 CVLLAKQSKDELSEARELG----NMGAVYIAMGDFENAVQCHEQHLKIAKDLGNKREEAR 395
Query: 446 AQVKLRDFESAVNNFEKALERAKLVHNNEAQQAIISALD-DANKGIIRELRKTNYVENLK 504
A L NF+KA+ V AQ+ + A++ A G+ R +E K
Sbjct: 396 AYSNLGSAYHYRRNFDKAMSYHNYV-LELAQELMEKAIEMRAYAGLGHAARCMQDLERAK 454
Query: 505 EKSEGEASLYED 516
+ E + + ED
Sbjct: 455 QYHEQQLGIAED 466
Score = 50.4 bits (119), Expect = 5e-06
Identities = 46/187 (24%), Positives = 81/187 (43%), Gaps = 18/187 (9%)
Query: 317 ELVGNLYSCIGNAQIELGQMEAALQSHRKDLEIAKEYDLPDAKSRALDNIGRVFARVGKF 376
E + S +G+ +G AL SH++ + +AK+ +++R L N+G V+ +G F
Sbjct: 311 EAASSALSSLGHVYTAIGDYPNALASHKQCVLLAKQSKDELSEARELGNMGAVYIAMGDF 370
Query: 377 QQAIDTWEEKIPLAKTTLEKTWLFHEIGRCYLELDQAWQAQNYGEKSQQCAEEEGDIEWQ 436
+ A+ E+ + +AK K E R Y L A+ + +K+ ++ +
Sbjct: 371 ENAVQCHEQHLKIAKDLGNK----REEARAYSNLGSAYHYRRNFDKAMSYHNYVLELAQE 426
Query: 437 LNASVLVAQAQVKLRDFESAVNNFEKALERAKLVHNNEAQQAIISALDD--------ANK 488
L + +A L + + LERAK H E Q I L D +N
Sbjct: 427 LMEKAIEMRAYAGLGHAARCMQD----LERAKQYH--EQQLGIAEDLKDRAAEGRASSNL 480
Query: 489 GIIRELR 495
GII +++
Sbjct: 481 GIIHQMK 487
Score = 50.4 bits (119), Expect = 5e-06
Identities = 38/175 (21%), Positives = 81/175 (46%), Gaps = 3/175 (1%)
Query: 320 GNLYSCIGNAQIELGQMEAALQSHRKDLEIAKEYDLPDAKSRALDNIGRVFARVGKFQQA 379
G Y +GNA LG + A++ HR++L+I+ E + +++ N+ + +G +A
Sbjct: 514 GRAYGNMGNAYNALGMYDQAVKYHRQELQISMEVNDRASQASTHGNLAVAYQALGAHDRA 573
Query: 380 IDTWEEKIPLAKTTLE---KTWLFHEIGRCYLELDQAWQAQNYGEKSQQCAEEEGDIEWQ 436
+ ++ + +A+ + + +G + + QA Y E+ + A + D+E +
Sbjct: 574 LQHYQNHLNIARELRDIQSEARALSNLGNFHCSRGEYVQAAPYYEQYLRLAPDLQDMEGE 633
Query: 437 LNASVLVAQAQVKLRDFESAVNNFEKALERAKLVHNNEAQQAIISALDDANKGII 491
+ A L +++ AV +E+ L AK +H+ +Q L A K ++
Sbjct: 634 GKVCHNLGYAHYCLGNYQEAVKYYEQDLALAKDLHDKLSQAKAYCNLGLAFKALL 688
Score = 46.6 bits (109), Expect = 7e-05
Identities = 42/196 (21%), Positives = 84/196 (42%), Gaps = 6/196 (3%)
Query: 317 ELVGNLYSCIGNAQIELGQMEAALQSHRKDLEIAKEYDLPDAKSRALDNIGRVFARVGKF 376
+L G+++S + +A LG E + ++DL++AK + RA N+G F G +
Sbjct: 231 KLRGSVFSALSSAYWSLGNTEKSTGYMQQDLDVAKTLGDQTGECRAHGNLGSAFFSKGNY 290
Query: 377 QQAIDTWEEKIPLAKTTLEK---TWLFHEIGRCYLELDQAWQAQNYGEKSQQCAEEEGDI 433
++A+ ++ LA ++ + +G Y + A ++ A++ D
Sbjct: 291 REALTNHRHQLVLAMKLKDREAASSALSSLGHVYTAIGDYPNALASHKQCVLLAKQSKDE 350
Query: 434 EWQLNASVLVAQAQVKLRDFESAVNNFEKALERAKLVHNNEAQQAIISALDDA---NKGI 490
+ + + + DFE+AV E+ L+ AK + N + S L A +
Sbjct: 351 LSEARELGNMGAVYIAMGDFENAVQCHEQHLKIAKDLGNKREEARAYSNLGSAYHYRRNF 410
Query: 491 IRELRKTNYVENLKEK 506
+ + NYV L ++
Sbjct: 411 DKAMSYHNYVLELAQE 426
Score = 43.5 bits (101), Expect = 6e-04
Identities = 39/181 (21%), Positives = 86/181 (47%), Gaps = 10/181 (5%)
Query: 318 LVGNLYSCIGNAQIELGQMEAALQSHRKDLEIAKEY-DLPDAKSRALDNIGRVFARVGKF 376
L + Y+ +G A + + + AL H ++LE+ +E DLP + RA ++ V+ +GK+
Sbjct: 752 LEASAYAALGTAYRMIQKYDKALGYHTQELEVYQELSDLP-GECRAHGHLAAVYMALGKY 810
Query: 377 QQAIDTWEEKIPLAKTTLE---KTWLFHEIGRCYLELDQAWQAQNYGEKS----QQCAEE 429
A +EE++ L + + + ++ +G + ++ +A Y E+ QQ +
Sbjct: 811 TMAFKCYEEQLDLGQKLKDPSLEAQVYGNMGITKMNMNVMEEAIGYFEQQLAMLQQLSGN 870
Query: 430 EGDIEWQLNASVLVAQAQVKLRDFESAVNNFEKALERAKLVHNNEAQQAIISALDDANKG 489
E ++ + A + L D+E A+ +E+ L A+ ++ + Q L + ++
Sbjct: 871 ESVLD-RGRAYGNLGDCYEALGDYEEAIKYYEQYLSVAQSLNRMQDQAKAYRGLGNGHRA 929
Query: 490 I 490
+
Sbjct: 930 M 930
Score = 42.0 bits (97), Expect = 0.002
Identities = 43/194 (22%), Positives = 84/194 (43%), Gaps = 5/194 (2%)
Query: 293 SLQKAEKVLKKVLEWNKEEVPNKDELVGNLYSCIGNAQIELGQMEAALQSHRKDLEIAKE 352
+ KA VLE +E + E+ Y+ +G+A + +E A Q H + L IA++
Sbjct: 409 NFDKAMSYHNYVLELAQELMEKAIEM--RAYAGLGHAARCMQDLERAKQYHEQQLGIAED 466
Query: 353 YDLPDAKSRALDNIGRVFARVGKFQQAIDTWEEKIPLAKTTLE---KTWLFHEIGRCYLE 409
A+ RA N+G + G + A+ + + +A+ + + + +G Y
Sbjct: 467 LKDRAAEGRASSNLGIIHQMKGDYDTALKLHKTHLCIAQELSDYAAQGRAYGNMGNAYNA 526
Query: 410 LDQAWQAQNYGEKSQQCAEEEGDIEWQLNASVLVAQAQVKLRDFESAVNNFEKALERAKL 469
L QA Y + Q + E D Q + +A A L + A+ +++ L A+
Sbjct: 527 LGMYDQAVKYHRQELQISMEVNDRASQASTHGNLAVAYQALGAHDRALQHYQNHLNIARE 586
Query: 470 VHNNEAQQAIISAL 483
+ + +++ +S L
Sbjct: 587 LRDIQSEARALSNL 600
Score = 40.8 bits (94), Expect = 0.004
Identities = 30/150 (20%), Positives = 70/150 (46%), Gaps = 7/150 (4%)
Query: 318 LVGNLYSCIGNAQIELGQMEAALQSHRKDLEIAKEYDLPDA---KSRALDNIGRVFARVG 374
L +Y +G ++ + ME A+ + L + ++ ++ + RA N+G + +G
Sbjct: 832 LEAQVYGNMGITKMNMNVMEEAIGYFEQQLAMLQQLSGNESVLDRGRAYGNLGDCYEALG 891
Query: 375 KFQQAIDTWEEKIPLAKTTLEKTWLFHEIGRCYLELDQAWQAQNYGEKSQQCAEEEGDIE 434
+++AI +E+ + +A++ + + Y L +A +++ C E+ +
Sbjct: 892 DYEEAIKYYEQYLSVAQSLNR----MQDQAKAYRGLGNGHRAMGSLQQALVCFEKRLVVA 947
Query: 435 WQLNASVLVAQAQVKLRDFESAVNNFEKAL 464
+L + AQA +L S + N+E+A+
Sbjct: 948 HELGEAFNKAQAYGELGSLHSQLGNYEQAI 977
Score = 35.0 bits (79), Expect = 0.23
Identities = 38/204 (18%), Positives = 84/204 (41%), Gaps = 8/204 (3%)
Query: 292 GSLQKAEKVLKKVLEWNKEEVPNKDELV-----GNLYSCIGNAQIELGQMEAALQSHRKD 346
G + + L++ +++++++ ++L G S +G G + AL+ H+
Sbjct: 441 GHAARCMQDLERAKQYHEQQLGIAEDLKDRAAEGRASSNLGIIHQMKGDYDTALKLHKTH 500
Query: 347 LEIAKEYDLPDAKSRALDNIGRVFARVGKFQQAIDTWEEKIPLAKTTLEKTWLFHEIGR- 405
L IA+E A+ RA N+G + +G + QA+ +++ ++ ++ G
Sbjct: 501 LCIAQELSDYAAQGRAYGNMGNAYNALGMYDQAVKYHRQELQISMEVNDRASQASTHGNL 560
Query: 406 --CYLELDQAWQAQNYGEKSQQCAEEEGDIEWQLNASVLVAQAQVKLRDFESAVNNFEKA 463
Y L +A + + A E DI+ + A + ++ A +E+
Sbjct: 561 AVAYQALGAHDRALQHYQNHLNIARELRDIQSEARALSNLGNFHCSRGEYVQAAPYYEQY 620
Query: 464 LERAKLVHNNEAQQAIISALDDAN 487
L A + + E + + L A+
Sbjct: 621 LRLAPDLQDMEGEGKVCHNLGYAH 644
Score = 32.7 bits (73), Expect = 1.1
Identities = 32/161 (19%), Positives = 72/161 (44%), Gaps = 11/161 (6%)
Query: 313 PNKDELVGNLYSC--IGNAQIELGQMEAALQSHRKDLEIAKEYDLPDAKSRALDNIGRVF 370
P+ ++ G C +G A LG + A++ + +DL +AK+ ++++A N+G F
Sbjct: 625 PDLQDMEGEGKVCHNLGYAHYCLGNYQEAVKYYEQDLALAKDLHDKLSQAKAYCNLGLAF 684
Query: 371 ARVGKFQQAIDTWEEKIPLAKTTLEKTWLFHEIGR------CYLELDQAWQAQNYGEKSQ 424
+ F +A + + + LA++ F +G C +++ A + + E+
Sbjct: 685 KALLNFSKAEECQKYLLSLAQSLNNSQAKFRALGNLGDIFICKKDINGAIK---FYEQQL 741
Query: 425 QCAEEEGDIEWQLNASVLVAQAQVKLRDFESAVNNFEKALE 465
A + D + +A + A ++ ++ A+ + LE
Sbjct: 742 GLAHQVKDRRLEASAYAALGTAYRMIQKYDKALGYHTQELE 782
>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
sapiens]
Length = 1938
Score = 55.1 bits (131), Expect = 2e-07
Identities = 126/529 (23%), Positives = 207/529 (39%), Gaps = 60/529 (11%)
Query: 154 NIKAQQKPQPMKHLLHPTKGEPKWKASLKSEKTVRQLLGELYVDKEYLEKLLLDEDLIKG 213
N K +Q+ ++ L K K +A L E+ R+L G+L + +E + L D+ I+
Sbjct: 1028 NAKLEQQTDDLEGSLEQEK---KLRADL--ERAKRKLEGDLKMSQESIMDLENDKQQIEE 1082
Query: 214 TMKGGLTVEDLIMTGINYLDTHS-NFWRQQKPIYAR--ERDRKLMQEKWLRDHKRRPSQT 270
+K + I+ HS F ++ K + AR E + ++ E LR +
Sbjct: 1083 KLKKKEFELSQLQAKIDDEQVHSLQFQKKIKELQARIEELEEEIEAEHTLRAKIEKQRSD 1142
Query: 271 AHYILKSLEDIDMLLTSGSAEGSLQ-----KAEKVLKKVLEWNKEEVPNKDELVGNLYSC 325
+ + LE+I L S S Q K E +K+ +E + L
Sbjct: 1143 ---LARELEEISERLEEASGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKK 1199
Query: 326 IGNAQIELGQMEAALQSHRKDLEIAKEYDLPDAKSRALDNIGRVFARVGKFQQAIDTWEE 385
++ ELG+ LQ ++ LE K +L NI + ++ T E+
Sbjct: 1200 QADSVAELGEQIDNLQRVKQKLEKEKS-ELKMEIDDMASNIEALSKSKSNIERTCRTVED 1258
Query: 386 KIPLAKTTLEK-TWLFHEIGRCYLELDQAWQAQNYGEKSQQCAEEEGDIEWQLNAS--VL 442
+ K E+ T L H++ L Q QN GE S + E+E I QL S L
Sbjct: 1259 QFSEIKAKDEQQTQLIHDLNMQKARL----QTQN-GELSHRVEEKESLIS-QLTKSKQAL 1312
Query: 443 VAQAQVKLRDFES---AVNNFEKALE---------RAKLVHNNEAQQAIISALDDANKGI 490
Q + R E A N AL+ R + EA+ + AL AN +
Sbjct: 1313 TQQLEELKRQMEEETKAKNAMAHALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEV 1372
Query: 491 IR--------ELRKTNYVENLKEK-------SEGEASLYEDRIITREKDMRRVRDEPEKV 535
+ +++T +E K+K +E + + EK +R++ E E +
Sbjct: 1373 AQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEENTETANSKCASLEKTKQRLQGEVEDL 1432
Query: 536 VKQWDHSEDEKET-DEDDEAFGEALQSPASGKQSVEAGKARSDLGAV-AKGLSGELGTRS 593
++ + S T D+ F + L A KQ ++ +A + ++ LS EL
Sbjct: 1433 MRDLERSHTACATLDKKQRNFDKVL---AEWKQKLDESQAELEAAQKESRSLSTELFKMR 1489
Query: 594 G--ETGRKLLEAGRRESREIYRRPSGELEQRLSGEFSRQEPEELKKLSE 640
E LE RRE++ + S EQ + QE E+ KKL E
Sbjct: 1490 NAYEEVVDQLETLRRENKNLQEEISDLTEQIAETGKNLQEAEKTKKLVE 1538
Score = 39.7 bits (91), Expect = 0.009
Identities = 86/411 (20%), Positives = 173/411 (42%), Gaps = 47/411 (11%)
Query: 281 IDMLLTSGSAEGSLQKAEKVLKKVLEWNKEEVPNKDELVGNLYSCIGNAQIELGQMEAAL 340
I LL S AE K +K+ E KEE+ + L + + E ++ +
Sbjct: 840 IKPLLKSAEAE----KEMATMKEDFERTKEELARSEARRKELEEKMVSLLQEKNDLQLQV 895
Query: 341 QSHRKDLEIAKEYDLPDAKSRALDNIGRVFARVGKFQQAIDTWEE---KIPLAKTTLEK- 396
QS ++L A+E KS+ L + A+V + + ++ EE ++ K LE
Sbjct: 896 QSETENLMDAEERCEGLIKSKIL-----LEAKVKELTERLEEEEEMNSELVAKKRNLEDK 950
Query: 397 -TWLFHEIGRCYLELDQAWQAQNYGE-KSQQCAEEEGDIEWQLNASVLVAQAQVKLRDFE 454
+ L +I L L + + ++ E K + +EE +E N S L + + +
Sbjct: 951 CSSLKRDIDDLELTLTKVEKEKHATENKVKNLSEEMTALEE--NISKLTKEKKSLQEAHQ 1008
Query: 455 SAVNNFEKALERAKLVHNNEAQQAIISALDDANKGIIRELRKTNYVENLKEKSEGEASLY 514
+++ + +E K+ + + DD + +E + +E K K EG+ +
Sbjct: 1009 QTLDDLQ--VEEDKVNGLIKINAKLEQQTDDLEGSLEQEKKLRADLERAKRKLEGDLKMS 1066
Query: 515 EDRIITREKDMRRVRDEPEKVVKQWDHSEDEKETDEDD-------------EAFGEALQS 561
++ I+ E D +++ ++ +K K+++ S+ + + D++ +A E L+
Sbjct: 1067 QESIMDLENDKQQIEEKLKK--KEFELSQLQAKIDDEQVHSLQFQKKIKELQARIEELEE 1124
Query: 562 PASGKQSVEA--GKARSDLGAVAKGLSGELGTRSGETGRKLLEAGRRESREIYRRPSGEL 619
+ ++ A K RSDL + +S L SG T ++ +RE+ +++ +L
Sbjct: 1125 EIEAEHTLRAKIEKQRSDLARELEEISERLEEASGATSAQIEMNKKREAE--FQKMRRDL 1182
Query: 620 EQRLSGEFSRQEPEELKKLSEVGRREPEELGKTQFGEIGETKKTGNEMEKE 670
E E + Q L + ELG+ +I ++ ++EKE
Sbjct: 1183 E-----EATLQHEATAATLRKKQADSVAELGE----QIDNLQRVKQKLEKE 1224
>gi|164519122 LGN protein [Homo sapiens]
Length = 684
Score = 54.3 bits (129), Expect = 4e-07
Identities = 54/228 (23%), Positives = 103/228 (45%), Gaps = 10/228 (4%)
Query: 320 GNLYSCIGNAQIELGQMEAALQSHRKDLEIAKEYDLPDAKSRALDNIGRVFARVGKFQQA 379
G + +GN LG A+ +H + L IAKE+ A+ RA N+G + +G+F+ A
Sbjct: 202 GRAFGNLGNTHYLLGNFRDAVIAHEQRLLIAKEFGDKAAERRAYSNLGNAYIFLGEFETA 261
Query: 380 IDTWEEKIPLAKTTLEK---TWLFHEIGRCYLELDQAWQAQNYGEKSQQCAEEEGDIEWQ 436
+ +++ + LA+ ++ + +G Y L +A +Y K A+E D +
Sbjct: 262 SEYYKKTLLLARQLKDRAVEAQSCYSLGNTYTLLQDYEKAIDYHLKHLAIAQELNDRIGE 321
Query: 437 LNASVLVAQAQVKLRDFESAVNNFEKALERAKLVHNNEAQQAIISALDDANKGIIRELRK 496
A + A L + + A++ EK LE ++ V + + L D +
Sbjct: 322 GRACWSLGNAYTALGNHDQAMHFAEKHLEISREVGDKSGELTARLNLSDLQMVLGLSYST 381
Query: 497 TNYVENLKEKSEGEASL--YEDRIITRE--KDMRRVRDEPEKVVKQWD 540
N + + E +E ++SL ++ R ++M ++ PEK V+ W+
Sbjct: 382 NNSI--MSENTEIDSSLNGVRPKLGRRHSMENMELMKLTPEK-VQNWN 426
Score = 38.1 bits (87), Expect = 0.027
Identities = 43/188 (22%), Positives = 76/188 (40%), Gaps = 23/188 (12%)
Query: 322 LYSCIGNAQIELGQMEAALQSHRKDLEIAKEYDLPDAKSRALDNIGRVFARVGKFQQAID 381
+YS +GNA L AL+ H DL +A+ +++A N+G +G F +AI
Sbjct: 64 IYSQLGNAYFYLHDYAKALEYHHHDLTLARTIGDQLGEAKASGNLGNTLKVLGNFDEAIV 123
Query: 382 TWEEKIPLAKTTLEKTW----------LFH------------EIGRCYLELDQAWQAQ-N 418
+ + +++ +K ++H ++G E+ A QA +
Sbjct: 124 CCQRHLDISRELNDKVGEARALYNLGNVYHAKGKSFGCPGPQDVGEFPEEVRDALQAAVD 183
Query: 419 YGEKSQQCAEEEGDIEWQLNASVLVAQAQVKLRDFESAVNNFEKALERAKLVHNNEAQQA 478
+ E++ GD Q A + L +F AV E+ L AK + A++
Sbjct: 184 FYEENLSLVTALGDRAAQGRAFGNLGNTHYLLGNFRDAVIAHEQRLLIAKEFGDKAAERR 243
Query: 479 IISALDDA 486
S L +A
Sbjct: 244 AYSNLGNA 251
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 50.4 bits (119), Expect = 5e-06
Identities = 105/463 (22%), Positives = 192/463 (41%), Gaps = 80/463 (17%)
Query: 246 YARERDRKLMQEKWLRDHKRRPSQTAHYILKSLEDIDMLLTSGSAEGSLQKAEKVLKKVL 305
+ E R++ +E+ L + +R + +++ + L A+ Q AE+ K++
Sbjct: 1336 FISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQ-AEREAKELQ 1394
Query: 306 EWNKEEVPNKDELVGNLYSCIGNAQIELGQMEAALQSHRKDLEIAKEYDLPDAKSRALDN 365
+ +EEV ++E A ++ Q + ++Q + L + E ++ AK+R +
Sbjct: 1395 QRMQEEVVRREE-----------AAVDAQQQKRSIQEELQQLRQSSEAEI-QAKARQAEA 1442
Query: 366 IGRVFARVGKFQQAIDTWEEKIPLAKTTLEKTWLFHEIGRCYLELD-----------QAW 414
R R+ EE+I + + LE T + G EL Q
Sbjct: 1443 AERSRLRI----------EEEIRVVRLQLEATE--RQRGGAEGELQALRARAEEAEAQKR 1490
Query: 415 QAQNYGEKSQQCAEEEGDIEWQLN---ASVLVAQAQVK------LRDFESAVNNFEKALE 465
QAQ E+ ++ ++E + Q AS + A+A+ L+ E E+A
Sbjct: 1491 QAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAER 1550
Query: 466 RAKLVHNNEAQQAIISALDDANKGIIRELR--------KTNYVE-NLKEKSEGEASLYED 516
R + A+Q + AL+ A + EL+ KT +E +L+E+ A L E+
Sbjct: 1551 RLRQAEVERARQVQV-ALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREE 1609
Query: 517 --RIITREKDMRRVRDEPEKVVKQWDHSEDEK---ETDEDDEAFGEALQSPASGKQSVEA 571
R ++ + R R+E E+ +++W +E ++ A ++L + KQ EA
Sbjct: 1610 AERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEA 1669
Query: 572 GKARSDLGAVAKGLSGELGTRSGETGRKLLEAGRRESREIYRRPSGELEQRLSGEFSRQE 631
+ A +G + E R E + LE R+ + G +QRL+ E QE
Sbjct: 1670 ERE-----ARRRGKAEEQAVRQRELAEQELEKQRQLA-------EGTAQQRLAAE---QE 1714
Query: 632 PEELKKLSEVGRRE----PEELGKTQFGEIGETKKTGNEMEKE 670
L+ +E G ++ EEL + Q T+K E+E E
Sbjct: 1715 LIRLRAETEQGEQQRQLLEEELARLQREAAAATQKR-QELEAE 1756
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 50.4 bits (119), Expect = 5e-06
Identities = 105/463 (22%), Positives = 192/463 (41%), Gaps = 80/463 (17%)
Query: 246 YARERDRKLMQEKWLRDHKRRPSQTAHYILKSLEDIDMLLTSGSAEGSLQKAEKVLKKVL 305
+ E R++ +E+ L + +R + +++ + L A+ Q AE+ K++
Sbjct: 1340 FISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQ-AEREAKELQ 1398
Query: 306 EWNKEEVPNKDELVGNLYSCIGNAQIELGQMEAALQSHRKDLEIAKEYDLPDAKSRALDN 365
+ +EEV ++E A ++ Q + ++Q + L + E ++ AK+R +
Sbjct: 1399 QRMQEEVVRREE-----------AAVDAQQQKRSIQEELQQLRQSSEAEI-QAKARQAEA 1446
Query: 366 IGRVFARVGKFQQAIDTWEEKIPLAKTTLEKTWLFHEIGRCYLELD-----------QAW 414
R R+ EE+I + + LE T + G EL Q
Sbjct: 1447 AERSRLRI----------EEEIRVVRLQLEATE--RQRGGAEGELQALRARAEEAEAQKR 1494
Query: 415 QAQNYGEKSQQCAEEEGDIEWQLN---ASVLVAQAQVK------LRDFESAVNNFEKALE 465
QAQ E+ ++ ++E + Q AS + A+A+ L+ E E+A
Sbjct: 1495 QAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAER 1554
Query: 466 RAKLVHNNEAQQAIISALDDANKGIIRELR--------KTNYVE-NLKEKSEGEASLYED 516
R + A+Q + AL+ A + EL+ KT +E +L+E+ A L E+
Sbjct: 1555 RLRQAEVERARQVQV-ALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREE 1613
Query: 517 --RIITREKDMRRVRDEPEKVVKQWDHSEDEK---ETDEDDEAFGEALQSPASGKQSVEA 571
R ++ + R R+E E+ +++W +E ++ A ++L + KQ EA
Sbjct: 1614 AERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEA 1673
Query: 572 GKARSDLGAVAKGLSGELGTRSGETGRKLLEAGRRESREIYRRPSGELEQRLSGEFSRQE 631
+ A +G + E R E + LE R+ + G +QRL+ E QE
Sbjct: 1674 ERE-----ARRRGKAEEQAVRQRELAEQELEKQRQLA-------EGTAQQRLAAE---QE 1718
Query: 632 PEELKKLSEVGRRE----PEELGKTQFGEIGETKKTGNEMEKE 670
L+ +E G ++ EEL + Q T+K E+E E
Sbjct: 1719 LIRLRAETEQGEQQRQLLEEELARLQREAAAATQKR-QELEAE 1760
>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
Length = 4547
Score = 50.4 bits (119), Expect = 5e-06
Identities = 105/463 (22%), Positives = 192/463 (41%), Gaps = 80/463 (17%)
Query: 246 YARERDRKLMQEKWLRDHKRRPSQTAHYILKSLEDIDMLLTSGSAEGSLQKAEKVLKKVL 305
+ E R++ +E+ L + +R + +++ + L A+ Q AE+ K++
Sbjct: 1336 FISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQ-AEREAKELQ 1394
Query: 306 EWNKEEVPNKDELVGNLYSCIGNAQIELGQMEAALQSHRKDLEIAKEYDLPDAKSRALDN 365
+ +EEV ++E A ++ Q + ++Q + L + E ++ AK+R +
Sbjct: 1395 QRMQEEVVRREE-----------AAVDAQQQKRSIQEELQQLRQSSEAEI-QAKARQAEA 1442
Query: 366 IGRVFARVGKFQQAIDTWEEKIPLAKTTLEKTWLFHEIGRCYLELD-----------QAW 414
R R+ EE+I + + LE T + G EL Q
Sbjct: 1443 AERSRLRI----------EEEIRVVRLQLEATE--RQRGGAEGELQALRARAEEAEAQKR 1490
Query: 415 QAQNYGEKSQQCAEEEGDIEWQLN---ASVLVAQAQVK------LRDFESAVNNFEKALE 465
QAQ E+ ++ ++E + Q AS + A+A+ L+ E E+A
Sbjct: 1491 QAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAER 1550
Query: 466 RAKLVHNNEAQQAIISALDDANKGIIRELR--------KTNYVE-NLKEKSEGEASLYED 516
R + A+Q + AL+ A + EL+ KT +E +L+E+ A L E+
Sbjct: 1551 RLRQAEVERARQVQV-ALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREE 1609
Query: 517 --RIITREKDMRRVRDEPEKVVKQWDHSEDEK---ETDEDDEAFGEALQSPASGKQSVEA 571
R ++ + R R+E E+ +++W +E ++ A ++L + KQ EA
Sbjct: 1610 AERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEA 1669
Query: 572 GKARSDLGAVAKGLSGELGTRSGETGRKLLEAGRRESREIYRRPSGELEQRLSGEFSRQE 631
+ A +G + E R E + LE R+ + G +QRL+ E QE
Sbjct: 1670 ERE-----ARRRGKAEEQAVRQRELAEQELEKQRQLA-------EGTAQQRLAAE---QE 1714
Query: 632 PEELKKLSEVGRRE----PEELGKTQFGEIGETKKTGNEMEKE 670
L+ +E G ++ EEL + Q T+K E+E E
Sbjct: 1715 LIRLRAETEQGEQQRQLLEEELARLQREAAAATQKR-QELEAE 1756
>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
Length = 4515
Score = 50.4 bits (119), Expect = 5e-06
Identities = 105/463 (22%), Positives = 192/463 (41%), Gaps = 80/463 (17%)
Query: 246 YARERDRKLMQEKWLRDHKRRPSQTAHYILKSLEDIDMLLTSGSAEGSLQKAEKVLKKVL 305
+ E R++ +E+ L + +R + +++ + L A+ Q AE+ K++
Sbjct: 1304 FISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQ-AEREAKELQ 1362
Query: 306 EWNKEEVPNKDELVGNLYSCIGNAQIELGQMEAALQSHRKDLEIAKEYDLPDAKSRALDN 365
+ +EEV ++E A ++ Q + ++Q + L + E ++ AK+R +
Sbjct: 1363 QRMQEEVVRREE-----------AAVDAQQQKRSIQEELQQLRQSSEAEI-QAKARQAEA 1410
Query: 366 IGRVFARVGKFQQAIDTWEEKIPLAKTTLEKTWLFHEIGRCYLELD-----------QAW 414
R R+ EE+I + + LE T + G EL Q
Sbjct: 1411 AERSRLRI----------EEEIRVVRLQLEATE--RQRGGAEGELQALRARAEEAEAQKR 1458
Query: 415 QAQNYGEKSQQCAEEEGDIEWQLN---ASVLVAQAQVK------LRDFESAVNNFEKALE 465
QAQ E+ ++ ++E + Q AS + A+A+ L+ E E+A
Sbjct: 1459 QAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAER 1518
Query: 466 RAKLVHNNEAQQAIISALDDANKGIIRELR--------KTNYVE-NLKEKSEGEASLYED 516
R + A+Q + AL+ A + EL+ KT +E +L+E+ A L E+
Sbjct: 1519 RLRQAEVERARQVQV-ALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREE 1577
Query: 517 --RIITREKDMRRVRDEPEKVVKQWDHSEDEK---ETDEDDEAFGEALQSPASGKQSVEA 571
R ++ + R R+E E+ +++W +E ++ A ++L + KQ EA
Sbjct: 1578 AERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEA 1637
Query: 572 GKARSDLGAVAKGLSGELGTRSGETGRKLLEAGRRESREIYRRPSGELEQRLSGEFSRQE 631
+ A +G + E R E + LE R+ + G +QRL+ E QE
Sbjct: 1638 ERE-----ARRRGKAEEQAVRQRELAEQELEKQRQLA-------EGTAQQRLAAE---QE 1682
Query: 632 PEELKKLSEVGRRE----PEELGKTQFGEIGETKKTGNEMEKE 670
L+ +E G ++ EEL + Q T+K E+E E
Sbjct: 1683 LIRLRAETEQGEQQRQLLEEELARLQREAAAATQKR-QELEAE 1724
>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
Length = 4684
Score = 50.4 bits (119), Expect = 5e-06
Identities = 105/463 (22%), Positives = 192/463 (41%), Gaps = 80/463 (17%)
Query: 246 YARERDRKLMQEKWLRDHKRRPSQTAHYILKSLEDIDMLLTSGSAEGSLQKAEKVLKKVL 305
+ E R++ +E+ L + +R + +++ + L A+ Q AE+ K++
Sbjct: 1473 FISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQ-AEREAKELQ 1531
Query: 306 EWNKEEVPNKDELVGNLYSCIGNAQIELGQMEAALQSHRKDLEIAKEYDLPDAKSRALDN 365
+ +EEV ++E A ++ Q + ++Q + L + E ++ AK+R +
Sbjct: 1532 QRMQEEVVRREE-----------AAVDAQQQKRSIQEELQQLRQSSEAEI-QAKARQAEA 1579
Query: 366 IGRVFARVGKFQQAIDTWEEKIPLAKTTLEKTWLFHEIGRCYLELD-----------QAW 414
R R+ EE+I + + LE T + G EL Q
Sbjct: 1580 AERSRLRI----------EEEIRVVRLQLEATE--RQRGGAEGELQALRARAEEAEAQKR 1627
Query: 415 QAQNYGEKSQQCAEEEGDIEWQLN---ASVLVAQAQVK------LRDFESAVNNFEKALE 465
QAQ E+ ++ ++E + Q AS + A+A+ L+ E E+A
Sbjct: 1628 QAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAER 1687
Query: 466 RAKLVHNNEAQQAIISALDDANKGIIRELR--------KTNYVE-NLKEKSEGEASLYED 516
R + A+Q + AL+ A + EL+ KT +E +L+E+ A L E+
Sbjct: 1688 RLRQAEVERARQVQV-ALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREE 1746
Query: 517 --RIITREKDMRRVRDEPEKVVKQWDHSEDEK---ETDEDDEAFGEALQSPASGKQSVEA 571
R ++ + R R+E E+ +++W +E ++ A ++L + KQ EA
Sbjct: 1747 AERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEA 1806
Query: 572 GKARSDLGAVAKGLSGELGTRSGETGRKLLEAGRRESREIYRRPSGELEQRLSGEFSRQE 631
+ A +G + E R E + LE R+ + G +QRL+ E QE
Sbjct: 1807 ERE-----ARRRGKAEEQAVRQRELAEQELEKQRQLA-------EGTAQQRLAAE---QE 1851
Query: 632 PEELKKLSEVGRRE----PEELGKTQFGEIGETKKTGNEMEKE 670
L+ +E G ++ EEL + Q T+K E+E E
Sbjct: 1852 LIRLRAETEQGEQQRQLLEEELARLQREAAAATQKR-QELEAE 1893
>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
Length = 4525
Score = 50.4 bits (119), Expect = 5e-06
Identities = 105/463 (22%), Positives = 192/463 (41%), Gaps = 80/463 (17%)
Query: 246 YARERDRKLMQEKWLRDHKRRPSQTAHYILKSLEDIDMLLTSGSAEGSLQKAEKVLKKVL 305
+ E R++ +E+ L + +R + +++ + L A+ Q AE+ K++
Sbjct: 1314 FISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQ-AEREAKELQ 1372
Query: 306 EWNKEEVPNKDELVGNLYSCIGNAQIELGQMEAALQSHRKDLEIAKEYDLPDAKSRALDN 365
+ +EEV ++E A ++ Q + ++Q + L + E ++ AK+R +
Sbjct: 1373 QRMQEEVVRREE-----------AAVDAQQQKRSIQEELQQLRQSSEAEI-QAKARQAEA 1420
Query: 366 IGRVFARVGKFQQAIDTWEEKIPLAKTTLEKTWLFHEIGRCYLELD-----------QAW 414
R R+ EE+I + + LE T + G EL Q
Sbjct: 1421 AERSRLRI----------EEEIRVVRLQLEATE--RQRGGAEGELQALRARAEEAEAQKR 1468
Query: 415 QAQNYGEKSQQCAEEEGDIEWQLN---ASVLVAQAQVK------LRDFESAVNNFEKALE 465
QAQ E+ ++ ++E + Q AS + A+A+ L+ E E+A
Sbjct: 1469 QAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAER 1528
Query: 466 RAKLVHNNEAQQAIISALDDANKGIIRELR--------KTNYVE-NLKEKSEGEASLYED 516
R + A+Q + AL+ A + EL+ KT +E +L+E+ A L E+
Sbjct: 1529 RLRQAEVERARQVQV-ALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREE 1587
Query: 517 --RIITREKDMRRVRDEPEKVVKQWDHSEDEK---ETDEDDEAFGEALQSPASGKQSVEA 571
R ++ + R R+E E+ +++W +E ++ A ++L + KQ EA
Sbjct: 1588 AERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEA 1647
Query: 572 GKARSDLGAVAKGLSGELGTRSGETGRKLLEAGRRESREIYRRPSGELEQRLSGEFSRQE 631
+ A +G + E R E + LE R+ + G +QRL+ E QE
Sbjct: 1648 ERE-----ARRRGKAEEQAVRQRELAEQELEKQRQLA-------EGTAQQRLAAE---QE 1692
Query: 632 PEELKKLSEVGRRE----PEELGKTQFGEIGETKKTGNEMEKE 670
L+ +E G ++ EEL + Q T+K E+E E
Sbjct: 1693 LIRLRAETEQGEQQRQLLEEELARLQREAAAATQKR-QELEAE 1734
>gi|41322912 plectin 1 isoform 2 [Homo sapiens]
Length = 4533
Score = 50.4 bits (119), Expect = 5e-06
Identities = 105/463 (22%), Positives = 192/463 (41%), Gaps = 80/463 (17%)
Query: 246 YARERDRKLMQEKWLRDHKRRPSQTAHYILKSLEDIDMLLTSGSAEGSLQKAEKVLKKVL 305
+ E R++ +E+ L + +R + +++ + L A+ Q AE+ K++
Sbjct: 1322 FISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQ-AEREAKELQ 1380
Query: 306 EWNKEEVPNKDELVGNLYSCIGNAQIELGQMEAALQSHRKDLEIAKEYDLPDAKSRALDN 365
+ +EEV ++E A ++ Q + ++Q + L + E ++ AK+R +
Sbjct: 1381 QRMQEEVVRREE-----------AAVDAQQQKRSIQEELQQLRQSSEAEI-QAKARQAEA 1428
Query: 366 IGRVFARVGKFQQAIDTWEEKIPLAKTTLEKTWLFHEIGRCYLELD-----------QAW 414
R R+ EE+I + + LE T + G EL Q
Sbjct: 1429 AERSRLRI----------EEEIRVVRLQLEATE--RQRGGAEGELQALRARAEEAEAQKR 1476
Query: 415 QAQNYGEKSQQCAEEEGDIEWQLN---ASVLVAQAQVK------LRDFESAVNNFEKALE 465
QAQ E+ ++ ++E + Q AS + A+A+ L+ E E+A
Sbjct: 1477 QAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAER 1536
Query: 466 RAKLVHNNEAQQAIISALDDANKGIIRELR--------KTNYVE-NLKEKSEGEASLYED 516
R + A+Q + AL+ A + EL+ KT +E +L+E+ A L E+
Sbjct: 1537 RLRQAEVERARQVQV-ALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREE 1595
Query: 517 --RIITREKDMRRVRDEPEKVVKQWDHSEDEK---ETDEDDEAFGEALQSPASGKQSVEA 571
R ++ + R R+E E+ +++W +E ++ A ++L + KQ EA
Sbjct: 1596 AERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEA 1655
Query: 572 GKARSDLGAVAKGLSGELGTRSGETGRKLLEAGRRESREIYRRPSGELEQRLSGEFSRQE 631
+ A +G + E R E + LE R+ + G +QRL+ E QE
Sbjct: 1656 ERE-----ARRRGKAEEQAVRQRELAEQELEKQRQLA-------EGTAQQRLAAE---QE 1700
Query: 632 PEELKKLSEVGRRE----PEELGKTQFGEIGETKKTGNEMEKE 670
L+ +E G ++ EEL + Q T+K E+E E
Sbjct: 1701 LIRLRAETEQGEQQRQLLEEELARLQREAAAATQKR-QELEAE 1742
>gi|47607492 plectin 1 isoform 1 [Homo sapiens]
Length = 4574
Score = 50.4 bits (119), Expect = 5e-06
Identities = 105/463 (22%), Positives = 192/463 (41%), Gaps = 80/463 (17%)
Query: 246 YARERDRKLMQEKWLRDHKRRPSQTAHYILKSLEDIDMLLTSGSAEGSLQKAEKVLKKVL 305
+ E R++ +E+ L + +R + +++ + L A+ Q AE+ K++
Sbjct: 1363 FISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQ-AEREAKELQ 1421
Query: 306 EWNKEEVPNKDELVGNLYSCIGNAQIELGQMEAALQSHRKDLEIAKEYDLPDAKSRALDN 365
+ +EEV ++E A ++ Q + ++Q + L + E ++ AK+R +
Sbjct: 1422 QRMQEEVVRREE-----------AAVDAQQQKRSIQEELQQLRQSSEAEI-QAKARQAEA 1469
Query: 366 IGRVFARVGKFQQAIDTWEEKIPLAKTTLEKTWLFHEIGRCYLELD-----------QAW 414
R R+ EE+I + + LE T + G EL Q
Sbjct: 1470 AERSRLRI----------EEEIRVVRLQLEATE--RQRGGAEGELQALRARAEEAEAQKR 1517
Query: 415 QAQNYGEKSQQCAEEEGDIEWQLN---ASVLVAQAQVK------LRDFESAVNNFEKALE 465
QAQ E+ ++ ++E + Q AS + A+A+ L+ E E+A
Sbjct: 1518 QAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAER 1577
Query: 466 RAKLVHNNEAQQAIISALDDANKGIIRELR--------KTNYVE-NLKEKSEGEASLYED 516
R + A+Q + AL+ A + EL+ KT +E +L+E+ A L E+
Sbjct: 1578 RLRQAEVERARQVQV-ALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREE 1636
Query: 517 --RIITREKDMRRVRDEPEKVVKQWDHSEDEK---ETDEDDEAFGEALQSPASGKQSVEA 571
R ++ + R R+E E+ +++W +E ++ A ++L + KQ EA
Sbjct: 1637 AERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEA 1696
Query: 572 GKARSDLGAVAKGLSGELGTRSGETGRKLLEAGRRESREIYRRPSGELEQRLSGEFSRQE 631
+ A +G + E R E + LE R+ + G +QRL+ E QE
Sbjct: 1697 ERE-----ARRRGKAEEQAVRQRELAEQELEKQRQLA-------EGTAQQRLAAE---QE 1741
Query: 632 PEELKKLSEVGRRE----PEELGKTQFGEIGETKKTGNEMEKE 670
L+ +E G ++ EEL + Q T+K E+E E
Sbjct: 1742 LIRLRAETEQGEQQRQLLEEELARLQREAAAATQKR-QELEAE 1783
>gi|224548927 G-protein signaling modulator 1 (AGS3-like, C.
elegans) isoform a [Homo sapiens]
Length = 675
Score = 48.9 bits (115), Expect = 2e-05
Identities = 40/174 (22%), Positives = 68/174 (39%), Gaps = 43/174 (24%)
Query: 320 GNLYSCIGNAQIELGQMEAALQSHRKDLEIAKEYDLPDAKSRALDNIGRVFARVGKFQQA 379
G Y +GN LG A H++ L IAKE+ A+ RA N+G +G+F A
Sbjct: 209 GRAYGNLGNTHYLLGNFTEATTFHKERLAIAKEFGDKAAERRAYSNLGNAHVFLGRFDVA 268
Query: 380 IDTWEEKIPLAK----------------------TTLEKTWLFH---------------- 401
+ +++ + L++ E+ +H
Sbjct: 269 AEYYKKTLQLSRQLRDQAVEAQACYSLGNTYTLLQDYERAAEYHLRHLLIAQELADRVGE 328
Query: 402 -----EIGRCYLELDQAWQAQNYGEKSQQCAEEEGDIEWQLNASVLVAQAQVKL 450
+G Y+ + + QA + +K Q ++E GD +L A + VAQ Q+ L
Sbjct: 329 GRACWSLGNAYVSMGRPAQALTFAKKHLQISQEIGDRHGELTARMNVAQLQLVL 382
Score = 38.9 bits (89), Expect = 0.016
Identities = 42/192 (21%), Positives = 77/192 (40%), Gaps = 26/192 (13%)
Query: 322 LYSCIGNAQIELGQMEAALQSHRKDLEIAKEYDLPDAKSRALDNIGRVFARVGKFQQAID 381
+YS +GNA L + AL+ H+ DL +A+ +++A N+G +G+F +A
Sbjct: 68 IYSQLGNAYFYLKEHGRALEYHKHDLLLARTIGDRMGEAKASGNLGNTLKVLGRFDEAAV 127
Query: 382 TWEEKIPLAKTTLEKTW---LFHEIGRCYLELDQ--AWQAQN------------------ 418
+ + +A+ +K + IG Y + +W A N
Sbjct: 128 CCQRHLSIAQEQGDKVGEARALYNIGNVYHAKGKQLSWNAANATQDPGHLPPDVRETLCK 187
Query: 419 ---YGEKSQQCAEEEGDIEWQLNASVLVAQAQVKLRDFESAVNNFEKALERAKLVHNNEA 475
+ E++ +E GD Q A + L +F A ++ L AK + A
Sbjct: 188 ASEFYERNLSLVKELGDRAAQGRAYGNLGNTHYLLGNFTEATTFHKERLAIAKEFGDKAA 247
Query: 476 QQAIISALDDAN 487
++ S L +A+
Sbjct: 248 ERRAYSNLGNAH 259
>gi|224548925 G-protein signaling modulator 1 (AGS3-like, C.
elegans) isoform b [Homo sapiens]
Length = 457
Score = 48.9 bits (115), Expect = 2e-05
Identities = 40/174 (22%), Positives = 68/174 (39%), Gaps = 43/174 (24%)
Query: 320 GNLYSCIGNAQIELGQMEAALQSHRKDLEIAKEYDLPDAKSRALDNIGRVFARVGKFQQA 379
G Y +GN LG A H++ L IAKE+ A+ RA N+G +G+F A
Sbjct: 209 GRAYGNLGNTHYLLGNFTEATTFHKERLAIAKEFGDKAAERRAYSNLGNAHVFLGRFDVA 268
Query: 380 IDTWEEKIPLAK----------------------TTLEKTWLFH---------------- 401
+ +++ + L++ E+ +H
Sbjct: 269 AEYYKKTLQLSRQLRDQAVEAQACYSLGNTYTLLQDYERAAEYHLRHLLIAQELADRVGE 328
Query: 402 -----EIGRCYLELDQAWQAQNYGEKSQQCAEEEGDIEWQLNASVLVAQAQVKL 450
+G Y+ + + QA + +K Q ++E GD +L A + VAQ Q+ L
Sbjct: 329 GRACWSLGNAYVSMGRPAQALTFAKKHLQISQEIGDRHGELTARMNVAQLQLVL 382
Score = 38.9 bits (89), Expect = 0.016
Identities = 42/192 (21%), Positives = 77/192 (40%), Gaps = 26/192 (13%)
Query: 322 LYSCIGNAQIELGQMEAALQSHRKDLEIAKEYDLPDAKSRALDNIGRVFARVGKFQQAID 381
+YS +GNA L + AL+ H+ DL +A+ +++A N+G +G+F +A
Sbjct: 68 IYSQLGNAYFYLKEHGRALEYHKHDLLLARTIGDRMGEAKASGNLGNTLKVLGRFDEAAV 127
Query: 382 TWEEKIPLAKTTLEKTW---LFHEIGRCYLELDQ--AWQAQN------------------ 418
+ + +A+ +K + IG Y + +W A N
Sbjct: 128 CCQRHLSIAQEQGDKVGEARALYNIGNVYHAKGKQLSWNAANATQDPGHLPPDVRETLCK 187
Query: 419 ---YGEKSQQCAEEEGDIEWQLNASVLVAQAQVKLRDFESAVNNFEKALERAKLVHNNEA 475
+ E++ +E GD Q A + L +F A ++ L AK + A
Sbjct: 188 ASEFYERNLSLVKELGDRAAQGRAYGNLGNTHYLLGNFTEATTFHKERLAIAKEFGDKAA 247
Query: 476 QQAIISALDDAN 487
++ S L +A+
Sbjct: 248 ERRAYSNLGNAH 259
>gi|16262452 cingulin [Homo sapiens]
Length = 1203
Score = 48.9 bits (115), Expect = 2e-05
Identities = 115/571 (20%), Positives = 228/571 (39%), Gaps = 112/571 (19%)
Query: 109 KLRPDREFRVGIQKAQEAINNSVGSPSSIKLENKGDLSFLSKQAENIKAQ-QKPQPMKH- 166
KL P + VG+++ E + KG+ +K+ +N+K + + ++H
Sbjct: 384 KLEPSQ---VGLERQLEEKTEECSRLQELLERRKGEAQQSNKELQNMKRLLDQGEDLRHG 440
Query: 167 -----------LLHPTKGEPKWKASLKSEKTVRQLLGELYVDKEYLEKLLLDEDLIKGTM 215
L H EP + LK R+LL E+ K+ +E+ L + +
Sbjct: 441 LETQVMELQNKLKHVQGPEPAKEVLLKDLLETRELLEEVLEGKQRVEEQLRLRERELTAL 500
Query: 216 KGGLTVEDLIMTGINYLDTHSNFWRQQKPIYARERDRKLMQEKWLRDHKRRPSQTAHYIL 275
KG L E + +R+++ + +++++ RD ++ +
Sbjct: 501 KGALKEE----------------------VASRDQEVEHVRQQYQRDTEQ--------LR 530
Query: 276 KSLEDIDMLLTSGSAEGSLQKAEKVLKKVLEWNKEEVPNKDELVGNLYSCIGNAQIELGQ 335
+S++D T A VLE ++++ LV L + E G
Sbjct: 531 RSMQD----ATQDHA-------------VLEAERQKM---SALVRGLQRELEETSEETGH 570
Query: 336 MEAALQSHRKDLEIAKE--YDLPDAKSRALDNIGRVFARVGKFQQAIDTWEEKIPLAKTT 393
++ Q +++DL K+ L K + +G + I+ + ++ A+ +
Sbjct: 571 WQSMFQKNKEDLRATKQELLQLRMEKEEMEEELG----------EKIEVLQRELEQARAS 620
Query: 394 LEKTWLFHEIGRCYLELDQAWQAQNYGEKSQQCAEEEGDIEWQLNASVLVAQAQVKLRDF 453
T + + L + + +SQ+ A D E + +VL +A + R+
Sbjct: 621 AGDTRQVEVLKKELLRTQEELKELQAERQSQEVAGRHRDRELEKQLAVLRVEAD-RGREL 679
Query: 454 ESAVNNFEKALE----------RAKLVHNNEAQQAIISALDDANKGIIRELRKTNYVENL 503
E +K L+ +AK+V EA+ ++ A + +RE ++ N +
Sbjct: 680 EEQNLQLQKTLQQLRQDCEEASKAKMV--AEAEATVLGQRRAAVETTLRETQEEN--DEF 735
Query: 504 KEKSEG-EASLYEDR--IITREKDMRRVRDEPEKVVKQWDHSEDEKETDEDDEAFGEALQ 560
+ + G E L E R + E R+RD+ +++ + E+ +++E
Sbjct: 736 RRRILGLEQQLKETRGLVDGGEAVEARLRDKLQRLEAEKQQLEEALNASQEEEG------ 789
Query: 561 SPASGKQSVEAGKARSDLGAVAKGLSGELGTRSGETGRKLLEAGRRESREIYRRPSGELE 620
S A+ K+++EA L +GL+ LG R L E G++ RE+ RR ELE
Sbjct: 790 SLAAAKRALEA-----RLEEAQRGLA-RLGQEQQTLNRALEEEGKQ--REVLRRGKAELE 841
Query: 621 Q--RLSGEFSRQEPEELKKLSEVGRREPEEL 649
+ RL + +EL+K+ E ++ ++L
Sbjct: 842 EQKRLLDRTVDRLNKELEKIGEDSKQALQQL 872
>gi|156104908 myosin heavy chain 6 [Homo sapiens]
Length = 1939
Score = 47.8 bits (112), Expect = 3e-05
Identities = 83/396 (20%), Positives = 163/396 (41%), Gaps = 36/396 (9%)
Query: 299 KVLKKVLEWNKEEVPNKDELVGNLYSCIGNAQI---ELGQMEAALQSHRKDLEI---AKE 352
K L K E KE K+E G + + ++ EL + +L + DL++ A++
Sbjct: 839 KPLLKSAETEKEMATMKEEF-GRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQ 897
Query: 353 YDLPDAKSRA---LDNIGRVFARVGKFQQAIDTWEEKIPLAKTTLEKTWLFHEIGRCYLE 409
+L DA+ R + N ++ A+V + + ++ EE A+ T +K L E +
Sbjct: 898 DNLNDAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMN--AELTAKKRKLEDECSELKKD 955
Query: 410 LDQAWQAQNYGEKSQQCAEEEGD--IEWQLNASVLVAQAQVKLRDFESAVNNF--EKALE 465
+D EK + E + E ++A+ + + + A + +E
Sbjct: 956 IDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQVE 1015
Query: 466 RAKLVHNNEAQQAIISALDDANKGIIRELRKTNYVENLKEKSEGEASLYEDRIITREKDM 525
K+ ++++ + +DD + +E + +E K K EG+ L ++ I+ E D
Sbjct: 1016 EDKVNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDK 1075
Query: 526 RRVRDEPEKVVKQWDHSEDEKETDEDDEAFGEALQSPASGKQS-----VEAGKARSDLGA 580
++ ++ +K K++D ++ + ED++ LQ Q+ E +A A
Sbjct: 1076 LQLEEKLKK--KEFDINQQNSKI-EDEQVLALQLQKKLKENQARIEELEEELEAERTARA 1132
Query: 581 VAKGLSGELGTRSGETGRKLLEAGRRESREIYRRPSGELEQRLSGEFS--RQEPEELKKL 638
+ L +L E +L EAG S +I E+ ++ EF R++ EE
Sbjct: 1133 KVEKLRSDLSRELEEISERLEEAGGATSVQI------EMNKKREAEFQKMRRDLEEATLQ 1186
Query: 639 SEVGRREPEELGKTQFGEIGE----TKKTGNEMEKE 670
E + E+GE ++ ++EKE
Sbjct: 1187 HEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKE 1222
>gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens]
Length = 2115
Score = 46.2 bits (108), Expect = 1e-04
Identities = 90/445 (20%), Positives = 181/445 (40%), Gaps = 72/445 (16%)
Query: 241 QQKPIYARERDRKLMQEKWLRDHKRRPSQTAHYILKSLEDIDMLLTSGSAEGSLQKAEKV 300
+++ RERD L Q + L K + L+ + SA+ S+ +A++
Sbjct: 590 EEREASLRERDAALKQLEALEKEKAAKLEILQQQLQVANE-----ARDSAQTSVTQAQR- 643
Query: 301 LKKVLEWNKEEVPNKDELVGNLYSCIGNAQIELGQMEAALQSHRKDLEIAKEYDLPDAKS 360
K E+ K E L +C+ A+ E Q EA Q +L++ E K
Sbjct: 644 -------EKAELSRKVE---ELQACVETARQE--QHEAQAQVAELELQLRSEQQKATEKE 691
Query: 361 RALDNIGRVFARVGKFQQAIDTWEEKIPLAKTTLEKTWLFHEIGRCYLELDQAWQAQNYG 420
R V + Q+ + +E + + K +LE ++ +A +
Sbjct: 692 R-------VAQEKDQLQEQLQALKESLKVTKGSLE---------------EEKRRAADAL 729
Query: 421 EKSQQC-----AEEEGDIEWQLNASVLVAQAQVKLRDFESAVNNFEKALERAKLVHNNEA 475
E+ Q+C AE +E + + + + E+ + +A + V E
Sbjct: 730 EEQQRCISELKAETRSLVEQHKRERKELEEERAGRKGLEARLQQLGEAHQAETEVLRREL 789
Query: 476 QQAIIS--ALDDANKGIIRELR--KTNYVENLKEKSEGEASLYEDRIITREKDMRRVRDE 531
+A+ + + + +++E+ + Y ++ +E+++ A +++++++T +++ + R E
Sbjct: 790 AEAMAAQHTAESECEQLVKEVAAWRERYEDSQQEEAQYGA-MFQEQLMTLKEECEKARQE 848
Query: 532 ----PEKVVKQWDHSEDEKETDEDDEAFGEALQSPASGKQSVEAGKARSDLGAVAKGLSG 587
EKV HSE + +++ A E + A Q V+ + R A+ L+
Sbjct: 849 LQEAKEKVAGIESHSELQISRQQNELA--ELHANLARALQQVQEKEVR------AQKLAD 900
Query: 588 ELGTRSGETGRKLLEAGRRESREIYRRPSGELEQRLSGEFSRQEPEELKKLSEVGRREPE 647
+L T + E R E+ R +GE ++ S E +K+ + G R+PE
Sbjct: 901 DLSTLQEKMAATSKEVARLETLV---RKAGEQQETASREL-------VKEPARAGDRQPE 950
Query: 648 ELGKTQFGEIGETKKTGNEMEKEYE 672
L + Q + T+ ME+E E
Sbjct: 951 WLEEQQGRQFCSTQAALQAMEREAE 975
Score = 38.1 bits (87), Expect = 0.027
Identities = 109/524 (20%), Positives = 205/524 (39%), Gaps = 80/524 (15%)
Query: 140 ENKGDLSFLSKQAENIKAQQKPQPMKHLLHP-TKGEPKWKASLKSEKTVRQLLGELYVDK 198
E GDLSF ++ + QQ + L +K +W L+ + + + L DK
Sbjct: 318 EENGDLSFKLREFAS-HLQQLQDALNELTEEHSKATQEW---LEKQAQLEKELSAALQDK 373
Query: 199 EYLEKLLLDEDLIKGTMKGGLTVEDLIMTGINYLDTHSNFWRQQKPIYARERDRKLMQEK 258
+ LE+ +++ ++ L+ H + + P +E+ L
Sbjct: 374 KCLEEK-----------------NEILQGKLSQLEEHLSQLQDNPP---QEKGEVLGDVL 413
Query: 259 WLRDHKRRPSQTAHYILKSLEDIDMLLTSGSAEGSLQKAEKVLKKVLEWNKEEVPNKDEL 318
L K+ + A + ++ML T + + AE+ +EE L
Sbjct: 414 QLETLKQEAATLAANNTQLQARVEMLETERGQQEAKLLAER------GHFEEEKQQLSSL 467
Query: 319 VGNLYSCIGNAQIELGQMEAALQSHRKDL-----EIAKEYDLPDAKSRALDNIGRVFARV 373
+ +L S I N ++E A Q+H L + E +A + D
Sbjct: 468 ITDLQSSISNLSQAKEELEQASQAHGARLTAQVASLTSELTTLNATIQQQDQ-----ELA 522
Query: 374 GKFQQAIDTWEEKIPLAKTTLEK----TWLFHEIGRCYLELDQ-AWQAQNYGEKSQQCAE 428
G QQA E++ LA+T ++ L H++ + L Q Q + EK + +
Sbjct: 523 GLKQQA---KEKQAQLAQTLQQQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQ 579
Query: 429 EEGDIEWQLNASVLVAQAQVKLRDFESAVNNFEKALERAK----------LVHNNEAQQA 478
+ + + + LR+ ++A+ E ALE+ K L NEA+ +
Sbjct: 580 DHAQ-----QLATAAEEREASLRERDAALKQLE-ALEKEKAAKLEILQQQLQVANEARDS 633
Query: 479 IISALDDANKGIIRELRKTNYVENLKEKSEGEASLYEDRIITREKDMRRVRDEPEKVVKQ 538
+++ A + RK ++ E + E + ++ E ++R E +K ++
Sbjct: 634 AQTSVTQAQREKAELSRKVEELQACVETARQEQHEAQAQVAELE---LQLRSEQQKATEK 690
Query: 539 WDHSEDEKETDEDDEAFGEALQSPASGKQSVEAGKAR-SDLGAVAKGLSGELGTRSGETG 597
++++ + E +A E+L+ K S+E K R +D + EL +
Sbjct: 691 ERVAQEKDQLQEQLQALKESLKVT---KGSLEEEKRRAADALEEQQRCISELKAET---- 743
Query: 598 RKLLEAGRRESREIYRRPSGE--LEQRLS--GEFSRQEPEELKK 637
R L+E +RE +E+ +G LE RL GE + E E L++
Sbjct: 744 RSLVEQHKRERKELEEERAGRKGLEARLQQLGEAHQAETEVLRR 787
>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
sapiens]
Length = 1939
Score = 46.2 bits (108), Expect = 1e-04
Identities = 121/539 (22%), Positives = 207/539 (38%), Gaps = 92/539 (17%)
Query: 178 KASLKSEKTVRQLLGELYVDKEYLEKLLLDEDLIKGTMKGGLTVEDLIMTGINYLDTHSN 237
KA +K E+ V L G L +K K+ +D + K ++G DL + + +D ++
Sbjct: 1026 KAKIKLEQQVDDLEGSLEQEK----KIRMDLERAKRKLEG-----DLKLAQESTMDIEND 1076
Query: 238 FWRQQKPIYARERDRKLMQEKWLRDHKRRPSQTAHYILKSLEDIDMLLTSGSAE-GSLQK 296
+ + + +E + +Q K + D + Q I + I+ L AE S K
Sbjct: 1077 KQQLDEKLKKKEFEMSGLQSK-IEDEQALGMQLQKKIKELQARIEELEEEIEAERASRAK 1135
Query: 297 AEKVLKKVLEWNKEEVPNKDELVGNLYSCIGNAQIELGQM-EAALQSHRKDLEIA----- 350
AEK + L EE+ + E G S AQIE+ + EA Q R+DLE A
Sbjct: 1136 AEKQ-RSDLSRELEEISERLEEAGGATS----AQIEMNKKREAEFQKMRRDLEEATLQHE 1190
Query: 351 --------KEYDLPDAKSRALDNIGRVFARVGK----FQQAIDTWE---EKIPLAKTTLE 395
K D +DN+ RV ++ K + ID E + AK LE
Sbjct: 1191 ATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLE 1250
Query: 396 KTWLFHEIGRCYLELDQAWQAQNYGEKSQQCAE---EEGDIEWQLNAS-VLVAQAQVKLR 451
K E ++ + Q + + + Q A E G+ QL+ LV+Q +
Sbjct: 1251 KMCRALEDQLSEIKTKEEEQQRLINDLTAQRARLQTESGEYSRQLDEKDTLVSQLSRGKQ 1310
Query: 452 DFESAVNNFEKALE-----RAKLVH------------------NNEAQQAIISALDDANK 488
F + ++ LE ++ L H EA+ + A+ AN
Sbjct: 1311 AFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQEAKAELQRAMSKANS 1370
Query: 489 GIIR--------ELRKTNYVENLKEK-------SEGEASLYEDRIITREKDMRRVRDEPE 533
+ + +++T +E K+K +E + + EK +R+++E E
Sbjct: 1371 EVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVE 1430
Query: 534 KVVKQWDHSED-----EKETDEDDEAFGEALQSPASGKQSVEAGKARSDLGAVAKGLSGE 588
++ + + +K+ D+ E Q +EA + S + LS E
Sbjct: 1431 DLMIDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKES------RSLSTE 1484
Query: 589 LGT--RSGETGRKLLEAGRRESREIYRRPSGELEQRLSGEFSRQEPEELKKLSEVGRRE 645
L + E LE +RE++ + + S EQ G E E++KK E + E
Sbjct: 1485 LFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKSE 1543
Score = 40.0 bits (92), Expect = 0.007
Identities = 83/399 (20%), Positives = 157/399 (39%), Gaps = 39/399 (9%)
Query: 294 LQKAEKVLKKVLEWNKEEVPNKDELVGNLYSCIGNAQIELGQMEAALQSHRKDLEI---A 350
L K+ + K++ +E K+EL + EL + L + DL++ A
Sbjct: 843 LLKSAETEKEMANMKEEFEKTKEELAKTEAK-----RKELEEKMVTLMQEKNDLQLQVQA 897
Query: 351 KEYDLPDAKSRALDNIGRVFARVGKFQQAIDTWEEKIPL-AKTTLEKTWLFHEIGRCYLE 409
+ L DA+ R I K ++ + E++ + A+ T +K L E +
Sbjct: 898 EADSLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKD 957
Query: 410 LDQAWQAQNYGEKSQQCAEEEGD--IEWQLNASVLVAQAQVKLRDFESAVNNFEKAL--E 465
+D EK + E + E +A+ + + + A L E
Sbjct: 958 IDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAE 1017
Query: 466 RAKLVHNNEAQQAIISALDDANKGIIRELRKTNYVENLKEKSEGEASLYEDRIITREKDM 525
K+ +A+ + +DD + +E + +E K K EG+ L ++ + E D
Sbjct: 1018 EDKVNTLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQESTMDIENDK 1077
Query: 526 RRVRDEPEKVVKQWDHSEDEKETDEDDEAFGEALQSPASGKQS--------VEAGKARSD 577
+++ ++ +K K+++ S + + ED++A G LQ Q+ +EA +A
Sbjct: 1078 QQLDEKLKK--KEFEMSGLQSKI-EDEQALGMQLQKKIKELQARIEELEEEIEAERASR- 1133
Query: 578 LGAVAKGLSGELGTRSGETGRKLLEAGRRESREIYRRPSGELEQRLSGEFS--RQEPEEL 635
A A+ +L E +L EAG S +I E+ ++ EF R++ EE
Sbjct: 1134 --AKAEKQRSDLSRELEEISERLEEAGGATSAQI------EMNKKREAEFQKMRRDLEEA 1185
Query: 636 KKLSEVGRREPEELGKTQFGEIGE----TKKTGNEMEKE 670
E + E+GE ++ ++EKE
Sbjct: 1186 TLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKE 1224
Score = 31.6 bits (70), Expect = 2.5
Identities = 72/366 (19%), Positives = 142/366 (38%), Gaps = 35/366 (9%)
Query: 286 TSGSAEGSLQKAEKVLKKVLEWNKEEVPNKDELVGNLYSCIGNAQIELGQMEAALQSHRK 345
T A+G+L+K + L+ L K + + L+ +L + Q E G E + Q K
Sbjct: 1241 TVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQRARLQTESG--EYSRQLDEK 1298
Query: 346 DLEIAKEYDLPDAKSRALDNIGRVFARVGK----FQQAIDTWEEKIPLAKTTLE-----K 396
D +++ A ++ ++ + R K A+ + L + E K
Sbjct: 1299 DTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQEAK 1358
Query: 397 TWLFHEIGRCYLELDQAWQAQNYGEKSQQCAEEEGDIEWQLNASVLVAQAQVKLRDFESA 456
L + + E+ Q W+ + + Q+ E E A +AQ + A
Sbjct: 1359 AELQRAMSKANSEVAQ-WRTKYETDAIQRTEELE-------EAKKKLAQRLQDAEEHVEA 1410
Query: 457 VNNFEKALERAKLVHNNEAQQAIISALDDANKGIIRELRKTNYVENLKEKSEGEASLYED 516
VN +LE+ K NE + +I ++ N +K + + + + +
Sbjct: 1411 VNAKCASLEKTKQRLQNEVEDLMID-VERTNAACAALDKKQRNFDKILAEWKQKCEETHA 1469
Query: 517 RIITREKDMRRVRDEPEKVVKQWDHSEDEKETDEDDEAFGEALQSPASG--KQSVEAGKA 574
+ +K+ R + E K+ ++ S D+ ET + + + LQ S +Q E GK
Sbjct: 1470 ELEASQKESRSLSTELFKIKNAYEESLDQLETLKRE---NKNLQQEISDLTEQIAEGGKR 1526
Query: 575 RSDLGAVAKGLSGELGTRSGETGRKLLEAGRRESREIYRRPSGELEQRLSGEFSRQEPEE 634
+L + K + E + L+A E+ G++ R+ E ++ + E
Sbjct: 1527 IHELEKIKKQVEQE---------KSELQAALEEAEASLEHEEGKI-LRIQLELNQVKSEV 1576
Query: 635 LKKLSE 640
+K++E
Sbjct: 1577 DRKIAE 1582
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 45.8 bits (107), Expect = 1e-04
Identities = 89/450 (19%), Positives = 170/450 (37%), Gaps = 23/450 (5%)
Query: 239 WRQQKPIYARERDRKLMQEKWLRDHKRRPSQTAHYILKSLEDIDMLLTSGSAEGSLQKAE 298
WRQ++ + +E+ + +EK R +R Q + + E L++ E
Sbjct: 237 WRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQE 296
Query: 299 KVLK--KVLEWNKEEVPNKDELVGNLYSCIGNAQIELGQMEAALQSHRKDLEIAKEYDLP 356
K L+ K L +E++ ++E + + + ++ + E L K + +E +
Sbjct: 297 KELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMR-EQEQKMR 355
Query: 357 DAKSRALDNIGRVFARVGKFQQAIDTW--EEKIPLAKTTLEKTWLFHEIGRCYLELDQAW 414
D + R + R+ + + ++ W EEK+ + E+ E E ++
Sbjct: 356 DQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKM 415
Query: 415 QAQNYG-------EKSQQCAEEEGDIEWQ----LNASVLVAQAQVKLRDFESAVNNFEKA 463
Q Q E QQ E+ + W+ + + + K+RD E EK
Sbjct: 416 QKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQ-EKK 474
Query: 464 LERAKLVHNNEAQ--QAIISALDDANKGIIRELRKTNYVENLKEKSEGEASLYEDRIITR 521
+ R + + E Q + D K +E R E L+EK E + ++ +
Sbjct: 475 MWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMRE--QKKMWQQ 532
Query: 522 EKDMRRVRDEPEKVVKQWDHSEDEKETDEDDEAFGEALQSPASGKQSVEAGKARSDLGAV 581
E+ MR + E+ K WD E +E + E + + ++ E + + +
Sbjct: 533 EEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMRE 592
Query: 582 AKGLSGELGTRSGETGRKLLEAGRRESREIYRRPSGELEQRL-SGEFSRQEPEELKKLSE 640
+ E + E K+ E + + E E+ + E QE EE E
Sbjct: 593 QEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQE 652
Query: 641 VGRREPEELGKTQFGEI-GETKKTGNEMEK 669
RE EE + Q ++ G+ +K + EK
Sbjct: 653 EKMREQEEKMREQEEKMQGQEEKMREQEEK 682
Score = 38.5 bits (88), Expect = 0.020
Identities = 54/333 (16%), Positives = 132/333 (39%), Gaps = 46/333 (13%)
Query: 233 DTHSNFWRQQKPIYARERDRKLMQEKWLRDHKRRPSQTAHYILKSLEDIDMLLTSGSAEG 292
+ WRQ++ ++ +E+ + ++K +RD + R + E
Sbjct: 328 EQEEKMWRQEERLWEQEKQMREQEQK-MRDQEERMWE-------------------QDER 367
Query: 293 SLQKAEKVLKKVLEWNKEEVPNKDELVGNLYSCIGNAQIELGQMEAALQSHRKDLEIAKE 352
+K E++ ++ W +EE ++E + + + + + E +Q +++ +E
Sbjct: 368 LREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEE 427
Query: 353 YD-----LPDAKSRALDNIGRVFARVGKFQQAIDTWEEKIPLAKTTL---EKTWLFHEIG 404
+ LP+ K + + ++ + ++ I EEKI + +K W ++
Sbjct: 428 KEWQQQRLPEQKEKLWEQ-----EKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMR 482
Query: 405 RCYLELDQAWQAQNYGEKSQQCAEEEGDIEWQLNASVLVAQA----QVKLRDFESAVNNF 460
+ DQ W+ + +Q ++ + W+ + + + Q K+ E +
Sbjct: 483 E---QEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREE 539
Query: 461 EKALERAKLVHNNEAQQAIISALDDANKGIIRELRKTNYVENLKEKSEGEASLYEDRIIT 520
+K E+ K + E + + + K + E E ++ E + E+++
Sbjct: 540 KKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWE 599
Query: 521 REKDMRRVRDEPEKVVKQWDHSEDEKETDEDDE 553
+E+ M+ E+ K W+ E E +E+D+
Sbjct: 600 QEEKMQ------EQEEKMWEQEEKMWEQEEEDK 626
Score = 32.7 bits (73), Expect = 1.1
Identities = 51/312 (16%), Positives = 131/312 (41%), Gaps = 39/312 (12%)
Query: 239 WRQQKPIYARERDRKLMQEKWLRDHKRRPSQTAHYILKSLEDIDMLLTSGSAEGSLQKAE 298
W Q+K ++ +E+ R+ + W ++ K R + + + D + + E +K E
Sbjct: 469 WGQEKKMWRQEKMREQEDQMWEQEEKMRDQE------QKMWDQEERMWE-QDERLREKEE 521
Query: 299 KVLKKVLEWNKEEVPNKDELVGNLYSCIGNAQIELGQMEAALQSHRK-----DLEIAKEY 353
++ ++ W +EE +++ + + ++ + E + +K ++ +E
Sbjct: 522 RMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEE 581
Query: 354 DLPDAKSRALDNIGRVFARVGKFQ-QAIDTWEEKIPLAKTTLEKTWLFHEIGRCYLELDQ 412
+ + + + + +++ + K Q Q WE++ EK W E + + +
Sbjct: 582 KMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQE--------EKMWEQEEEDKMQEQEEM 633
Query: 413 AWQAQNYGEKSQQCAEEEGDIEWQLNASVLVAQAQVKLRDFESAVNNFEKALERAKLVHN 472
W+ + EK Q+ E+ + E ++ + + K+R+ E + E+ + +
Sbjct: 634 MWEQE---EKMQEQEEKMWEQEEKMR------EQEEKMREQEEKMQGQEEKMREQE--EK 682
Query: 473 NEAQQAIISALDDANKGIIRELRKTNYVENLKEKSEGEASLYEDRIITREKDMRRVRDEP 532
+ Q+ + ++ +G + + +EK G+ + REK+ R+RD+
Sbjct: 683 MQGQEEKMREQEEKMRG------QEEKMWGQEEKMWGQEEKMWGQEEMREKE-ERIRDQK 735
Query: 533 EKVVKQWDHSED 544
EK+ ++ E+
Sbjct: 736 EKMQERLPEHEE 747
>gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]
Length = 1946
Score = 45.4 bits (106), Expect = 2e-04
Identities = 123/578 (21%), Positives = 229/578 (39%), Gaps = 102/578 (17%)
Query: 144 DLSFLSKQAENIK-AQQKPQPMKHLLHPTKGEPKWKASLKSEKTVRQLLGELYVDKEYLE 202
D+S L++ A+ ++ A Q+ H+ K KA+LK E+ V +L G L ++E
Sbjct: 1000 DISKLNRAAKVVQEAHQQTLDDLHM-EEEKLSSLSKANLKLEQQVDELEGAL--EQERKA 1056
Query: 203 KLLLDEDLIKGTMKGGLTVEDLIMTGINYLDTHSNFWRQQKPIYARERDRKLMQEKWLRD 262
++ + +L K ++G L + M + H ++K + + + K+ EK L
Sbjct: 1057 RMNCERELHK--LEGNLKLNRESMENLESSQRHLAEELRKKELELSQMNSKVENEKGLVA 1114
Query: 263 HKRRPSQTAHYILKSLEDIDMLLTSGSAEGSLQKAEKVLKKVLEWNKEEVPNKDELVGNL 322
++ + +K L++ L + +++ L + L E + +E+ G+
Sbjct: 1115 QLQKTVKELQTQIKDLKE--KLEAERTTRAKMERERADLTQDLADLNERL---EEVGGSS 1169
Query: 323 YSCIGNAQIELGQ-MEAALQSHRKDLEIAK---EYDLPDAKSRALDNIGRVFARVGKFQQ 378
AQ+E+ + E Q +D+E A E K R D++ + +V QQ
Sbjct: 1170 L-----AQLEITKKQETKFQKLHRDMEEATLHFETTSASLKKRHADSLAELEGQVENLQQ 1224
Query: 379 AIDTWE-----------------EKIPLAKTTLEKTWLFHE--IGRCYLELDQAWQ-AQN 418
E E++ AK EK +E + +LD+ Q A +
Sbjct: 1225 VKQKLEKDKSDLQLEVDDLLTRVEQMTRAKANAEKLCTLYEERLHEATAKLDKVTQLAND 1284
Query: 419 YGEKSQQCAEEEGDIEWQLNASVLVAQAQVKLRDFESAVNNFEKALE--RAKLVHNNEAQ 476
+ + E G+ +L + + + +NF + +E R +L ++Q
Sbjct: 1285 LAAQKTKLWSESGEFLRRLE------EKEALINQLSREKSNFTRQIEDLRGQLEKETKSQ 1338
Query: 477 QAIISALDDANKGIIRELRKTNYVENLKEKSEGEASLYEDRIITREKDMRRVRDEPEKVV 536
A+ AL A + +L + Y E + K+E +L + + E R++ E +
Sbjct: 1339 SALAHALQKAQRDC--DLLREQYEEEQEVKAELHRTLSK---VNAEMVQWRMKYENNVIQ 1393
Query: 537 KQWDHSEDEKET----DEDDEAFGEALQSPASGKQS-----VEAGKARSDLGAVAKGLS- 586
+ D + +KE E EA G A AS +++ +E G A SDLG V +
Sbjct: 1394 RTEDLEDAKKELAIRLQEAAEAMGVANARNASLERARHQLQLELGDALSDLGKVRSAAAR 1453
Query: 587 -GELGTRSG----------ETGRKLLEAGRRE--------------------SREIYRRP 615
+ +SG E + LL+A ++E +E RR
Sbjct: 1454 LDQKQLQSGKALADWKQKHEESQALLDASQKEVQALSTELLKLKNTYEESIVGQETLRRE 1513
Query: 616 SGELEQRLS--------GEFSRQEPEELKKLSEVGRRE 645
+ L++ +S G + E E++KKL E + E
Sbjct: 1514 NKNLQEEISNLTNQVREGTKNLTEMEKVKKLIEEEKTE 1551
>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
sapiens]
Length = 1935
Score = 45.1 bits (105), Expect = 2e-04
Identities = 86/396 (21%), Positives = 157/396 (39%), Gaps = 36/396 (9%)
Query: 299 KVLKKVLEWNKEEVPNKDELVGNLYSCIGNAQI---ELGQMEAALQSHRKDLEI---AKE 352
K L K E KE K+E L + ++ EL + +L + DL++ A++
Sbjct: 837 KPLLKSAEREKEMASMKEEFT-RLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQ 895
Query: 353 YDLPDAKSRA---LDNIGRVFARVGKFQQAIDTWEEKIPLAKTTLEKTWLFHEIGRCYLE 409
+L DA+ R + N ++ A+V + + ++ EE A+ T +K L E +
Sbjct: 896 DNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMN--AELTAKKRKLEDECSELKRD 953
Query: 410 LDQAWQAQNYGEKSQQCAEEEGD--IEWQLNASVLVAQAQVKLRDFESAVNNFEKAL--E 465
+D EK + E + E ++A+ + + + A L E
Sbjct: 954 IDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAE 1013
Query: 466 RAKLVHNNEAQQAIISALDDANKGIIRELRKTNYVENLKEKSEGEASLYEDRIITREKDM 525
K+ +A+ + +DD + +E + +E K K EG+ L ++ I+ E D
Sbjct: 1014 EDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDK 1073
Query: 526 RRVRDEPEKVVKQWDHSEDEKETDEDDEAFGEALQSPASGKQS-----VEAGKARSDLGA 580
+++ E++ K+ ED++A G LQ Q+ E +A A
Sbjct: 1074 QQL---DERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARA 1130
Query: 581 VAKGLSGELGTRSGETGRKLLEAGRRESREIYRRPSGELEQRLSGEFS--RQEPEELKKL 638
+ L +L E +L EAG S +I E+ ++ EF R++ EE
Sbjct: 1131 KVEKLRSDLSRELEEISERLEEAGGATSVQI------EMNKKREAEFQKMRRDLEEATLQ 1184
Query: 639 SEVGRREPEELGKTQFGEIGE----TKKTGNEMEKE 670
E + E+GE ++ ++EKE
Sbjct: 1185 HEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKE 1220
>gi|89179321 smooth muscle cell associated protein-1 isoform 3 [Homo
sapiens]
Length = 929
Score = 45.1 bits (105), Expect = 2e-04
Identities = 29/117 (24%), Positives = 57/117 (48%), Gaps = 9/117 (7%)
Query: 19 EGERLYLCGEFSKAAQSFSNALYLQDGDKNCLVA---RSKCFLKMGDLERSLKDAEASLQ 75
EG L+ CG++ A +++ AL L ++ V R+ C LK+ D +++ +A +++
Sbjct: 12 EGNELFKCGDYGGALAAYTQALGLDATPQDQAVLHRNRAACHLKLEDYDKAETEASKAIE 71
Query: 76 SDPAFCKGILQKAETLYTMGDFEFALVFYHRGYKLRPDREFRVGIQKAQEAINNSVG 132
D K + ++++ L +G + A++ R L P + QEA+ N G
Sbjct: 72 KDGGDVKALYRRSQALEKLGRLDQAVLDLQRCVSLEPKNKV------FQEALRNIGG 122
Score = 30.0 bits (66), Expect = 7.2
Identities = 27/111 (24%), Positives = 48/111 (43%), Gaps = 11/111 (9%)
Query: 28 EFSKAAQSFSNALYLQDGDKNCLVARSKCFLKMGDLERSLKDAEASLQSDPAFCKGILQK 87
++ KA S A+ GD L RS+ K+G L++++ D + + +P + Q
Sbjct: 58 DYDKAETEASKAIEKDGGDVKALYRRSQALEKLGRLDQAVLDLQRCVSLEPK--NKVFQ- 114
Query: 88 AETLYTMGDFEFALVFYHRGYKLRPDREFRV-------GIQKAQEAINNSV 131
E L +G V Y + ++ F++ G +K Q+A N V
Sbjct: 115 -EALRNIGGQIQEKVRYMSSTDAKVEQMFQILLDPEEKGTEKKQKASQNLV 164
>gi|29725607 smooth muscle cell associated protein-1 isoform 2 [Homo
sapiens]
Length = 944
Score = 45.1 bits (105), Expect = 2e-04
Identities = 29/117 (24%), Positives = 57/117 (48%), Gaps = 9/117 (7%)
Query: 19 EGERLYLCGEFSKAAQSFSNALYLQDGDKNCLVA---RSKCFLKMGDLERSLKDAEASLQ 75
EG L+ CG++ A +++ AL L ++ V R+ C LK+ D +++ +A +++
Sbjct: 27 EGNELFKCGDYGGALAAYTQALGLDATPQDQAVLHRNRAACHLKLEDYDKAETEASKAIE 86
Query: 76 SDPAFCKGILQKAETLYTMGDFEFALVFYHRGYKLRPDREFRVGIQKAQEAINNSVG 132
D K + ++++ L +G + A++ R L P + QEA+ N G
Sbjct: 87 KDGGDVKALYRRSQALEKLGRLDQAVLDLQRCVSLEPKNKV------FQEALRNIGG 137
Score = 30.0 bits (66), Expect = 7.2
Identities = 27/111 (24%), Positives = 48/111 (43%), Gaps = 11/111 (9%)
Query: 28 EFSKAAQSFSNALYLQDGDKNCLVARSKCFLKMGDLERSLKDAEASLQSDPAFCKGILQK 87
++ KA S A+ GD L RS+ K+G L++++ D + + +P + Q
Sbjct: 73 DYDKAETEASKAIEKDGGDVKALYRRSQALEKLGRLDQAVLDLQRCVSLEPK--NKVFQ- 129
Query: 88 AETLYTMGDFEFALVFYHRGYKLRPDREFRV-------GIQKAQEAINNSV 131
E L +G V Y + ++ F++ G +K Q+A N V
Sbjct: 130 -EALRNIGGQIQEKVRYMSSTDAKVEQMFQILLDPEEKGTEKKQKASQNLV 179
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 43.9 bits (102), Expect = 5e-04
Identities = 45/167 (26%), Positives = 64/167 (38%), Gaps = 21/167 (12%)
Query: 504 KEKSEGEASLYEDRIITREKDMRRVRDEPEKVVKQWDHSEDEKETDEDDEAFGEALQSPA 563
K + EGE E E + E E+ +W+ E+E E + ++E GE +
Sbjct: 920 KGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEG 979
Query: 564 SGKQSVEAGKARSDLGAVAKGLSGELGTRSGETGRKLLEAGRRESREIYRRPSGELEQRL 623
G++ G+ E G GE + E G E E GE+E +
Sbjct: 980 EGEEEEGEGEGEE-----------EEGEEEGEEEGEGEEEGEGEGEE---EEEGEVEGEV 1025
Query: 624 SGEFSRQEPEELKKLSEVGRREPEELGKTQFGEIGETKKTGNEMEKE 670
GE E EE E G E EE K GE E ++ E E+E
Sbjct: 1026 EGEEGEGEGEE-----EEGEEEGEEREKEGEGE--ENRRNREEEEEE 1065
Score = 41.6 bits (96), Expect = 0.002
Identities = 62/258 (24%), Positives = 99/258 (38%), Gaps = 19/258 (7%)
Query: 420 GEKSQQCAEEEGDIEWQLNASVLVAQAQVKLRDFESAVNNFEKALERAKLVHNNEAQQAI 479
GE ++ AE+E EW+ + + K R+ ++ E + H ++
Sbjct: 690 GEGEKELAEKE---EWKKRDG---EEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEG 743
Query: 480 ISALDDANKGIIRELRKTNYVENLKEKSEGEASLYEDRIITREKDMR---RVRDEPEKVV 536
++ +G +E + VE +EK EGE E+R EK + E E+
Sbjct: 744 DREEEEEKEGEGKEEGEGEEVEGEREKEEGERKK-EERAGKEEKGEEEGDQGEGEEEETE 802
Query: 537 KQWDHSED--EKETDEDDEAFGEALQSPASGKQSVEAGKARSDLGAVAKGLSGELGTRSG 594
+ + E+ E E E +E GE + G+ E G+ + G + G G
Sbjct: 803 GRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEG 862
Query: 595 ETGRKLLEAGRRESREIYRRPSGELEQRLSGEFSRQEPEELKKLSEVGRREPEELGKTQF 654
E G E E GE E+ GE +E E G E E G+ +
Sbjct: 863 EEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGE------GEGEEEGEGEGEEEE 916
Query: 655 GEIGETKKTGNEMEKEYE 672
GE G+ ++ G E E E E
Sbjct: 917 GE-GKGEEEGEEGEGEGE 933
Score = 37.7 bits (86), Expect = 0.035
Identities = 65/253 (25%), Positives = 105/253 (41%), Gaps = 43/253 (16%)
Query: 456 AVNNFEKALERAKLVHNNEAQQAIISALDDANKGIIRELRKTNYVENLKEKSEGEAS--- 512
++N+ EK+L+ + V + QQ I D + E ++ E + E EG+A
Sbjct: 507 SLNSNEKSLKLSP-VQKQKKQQTIGELTQDT---ALTENDDSDEYEEMSEMKEGKACKQH 562
Query: 513 LYEDRIITREKD-MRRVRDEPEKVVKQWDHSEDEK----------ETDEDDEAFG----- 556
+ + +T+ + DE ++ ++ + +ED K +E+ + G
Sbjct: 563 VSQGIFMTQPATTIEAFSDEEVEIPEEKEGAEDSKGNGIEEQEVEANEENVKVHGGRKEK 622
Query: 557 -EALQSPASGKQSVEAGKARSDLGAVAKGLSGELGTRSGETGRKLLEAGRRESREIYRRP 615
E L + K V GKA+S +G G G G + E G E + E RE +
Sbjct: 623 TEILSDDLTDKAEVSEGKAKS-VGEAEDGPEGR-GDGTCEEGSSGAEHWQDEEREKGEKD 680
Query: 616 SG--ELEQRLSGEFSRQEPEELKKLS---------EVG-----RREPEELGKTQFGEIGE 659
G E+E+ GE E EE KK E G +E EE G+ + GE GE
Sbjct: 681 KGRGEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGE-GE 739
Query: 660 TKKTGNEMEKEYE 672
++ E E+E E
Sbjct: 740 EEEGDREEEEEKE 752
Score = 36.6 bits (83), Expect = 0.077
Identities = 45/171 (26%), Positives = 67/171 (39%), Gaps = 9/171 (5%)
Query: 505 EKSEGEASLYEDRIITREKDMRRVRDEPEKVVKQWDHSEDEKETD-EDDEAFGEALQSPA 563
E+ EGE E+ E++ + E E + + E+E E + ED E GE +
Sbjct: 896 EEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEW 955
Query: 564 SGKQSVEAGKARSDLGAVAKGLSGELGTRSGETGRKLLEAGRRESREIYRRPSGELEQRL 623
G++ G+ + + GE GE G E G E E GE E+
Sbjct: 956 EGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGE-GEGEEEEGEEEGEE-----EGEGEEEG 1009
Query: 624 SGEFSRQEPEELKKL--SEVGRREPEELGKTQFGEIGETKKTGNEMEKEYE 672
GE +E E++ E G E EE + GE E + G E + E
Sbjct: 1010 EGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNRE 1060
Score = 36.2 bits (82), Expect = 0.10
Identities = 42/172 (24%), Positives = 69/172 (40%), Gaps = 25/172 (14%)
Query: 503 LKEKSEGEASLYEDRIITREKDMRRVRDEPEKVVKQWDHSEDEKETDED--DEAFGEALQ 560
++ EGE L E +E+ +R +E E+ ++ H ++ + E+ +E GE +
Sbjct: 686 MERPGEGEKELAE-----KEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEE 740
Query: 561 SPASGKQSVEAGKARSDLGAVAKGLSGELGTRSGETGRKLLEAGRRESREIYRRPSGELE 620
++ E +G E G G + E G R+ E R E +
Sbjct: 741 EEGDREEEEEK-----------EGEGKEEGEGEEVEGEREKEEGERKKEE---RAGKEEK 786
Query: 621 QRLSGEFSRQEPEELKKLSEVGRREPEELGKTQFGEIGETKKTGNEMEKEYE 672
G+ E EE + E E EE G+ + GE+ E K E E+E E
Sbjct: 787 GEEEGDQGEGEEEETEGRGE----EKEEGGEVEGGEVEEGKGEREEEEEEGE 834
Score = 35.0 bits (79), Expect = 0.23
Identities = 35/139 (25%), Positives = 57/139 (41%), Gaps = 15/139 (10%)
Query: 504 KEKSEGEASLYEDRIITREKDMRRVRDEPEKVVKQWDHSEDEKETDEDDEAFGEALQSPA 563
+E+ EGE E E + +E E+ ++ E+E E + ++E GE
Sbjct: 967 EEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEV----- 1021
Query: 564 SGKQSVEAGKARSDLGAVAKGLSGELGTRSGETGRKLLEAGR-RESREIYRRPSGELEQR 622
G+ E G+ + E G GE K E R +RE G+ ++
Sbjct: 1022 EGEVEGEEGEGEGE---------EEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQET 1072
Query: 623 LSGEFSRQEPEELKKLSEV 641
E RQ+ EE KK+S++
Sbjct: 1073 GEEENERQDGEEYKKVSKI 1091
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 43.5 bits (101), Expect = 6e-04
Identities = 102/495 (20%), Positives = 193/495 (38%), Gaps = 72/495 (14%)
Query: 241 QQKPIYARERDRKLMQEKWLRDHKRRPSQTAHYILKSLEDIDML--LTSGSAEGSLQKAE 298
Q+K A+E+++ +++ L +K R + + +++ + M + + E Q+ E
Sbjct: 1841 QEKKNLAQEKEKLAQRKENLLYNKERLTHSKKQLVQVKNKLGMFNKILAQVEEKLTQEKE 1900
Query: 299 KVLKKVLEWNKEEVPNKDELVGNLYSCIGNAQIELGQ--MEAALQSH--------RKDLE 348
V+KK KE++ ++ + + + Q +L Q M+ AL+ R +L+
Sbjct: 1901 TVIKK-----KEKLAETEKKLVQVEDSLAKKQEKLAQEKMKLALEKAMVQGKKRLRGELD 1955
Query: 349 IAKEYD--------LPDAKSRALDNIGRVFARVGKF-----QQAIDTWEEKIPLAKTTLE 395
IAKE L + K R ++ G+ G+ Q+ + E+++ K +LE
Sbjct: 1956 IAKEEKALNLEMKRLAEEKMRLVE--GKETLSKGETPETSRQRKMTQVEQELFERKLSLE 2013
Query: 396 KTWLFHE----------IGRCYLELDQAWQAQNYGE------------KSQQCAEEEGDI 433
+ L HE I + LE + + G+ K + ++E +
Sbjct: 2014 EKILLHEDRILAMEESEIAKGKLEFTRGQRIFVQGQRKLAKASRKLIKKRESLSKEPAKL 2073
Query: 434 EWQLNASVLVAQAQVKLRDFESAVNNFEKAL---------ERAKLVHNNEAQQAIISALD 484
L A + + + KL E + ++AL E++KL S L
Sbjct: 2074 NKILKALQKLTRDERKLTQEEIKMTKMKRALFVKERRLSIEQSKLDIKEWDFSEKRSELT 2133
Query: 485 DANKGIIRELRKT--------NYVENLKEKSEGEASLYEDRIITREKDMRRVRDEPEKVV 536
K + R+ RK N E + E+ A + + I+ E++ +E +
Sbjct: 2134 KDEKKLARKQRKLANKMRRMINKEEKMTEEESKLARKHSEVILDDEEEGGIEEEEVIPFL 2193
Query: 537 KQ-WDHSEDEKETDEDDEAFGEALQSPASGKQSVEAGKARSDLGAVAKGLSGELGTRSGE 595
K+ W ++ K D+ E F + S + E ++ D + LS E E
Sbjct: 2194 KRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREE 2253
Query: 596 TGRKLLEAGRRESREIYRRPSGELEQRLSGEFSRQEPEELKKLSEVGRREPEELGKTQFG 655
+ E R E E GE +Q E +++ ++ KK EV +E K +
Sbjct: 2254 EEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIM 2313
Query: 656 EIGETKKTGNEMEKE 670
ET+ +E E+E
Sbjct: 2314 SEEETESLSDEEEEE 2328
Score = 31.6 bits (70), Expect = 2.5
Identities = 81/455 (17%), Positives = 175/455 (38%), Gaps = 40/455 (8%)
Query: 241 QQKPIYARER----------DRKLMQEKWLRDHKRRPSQTAHYILKSLEDIDMLLTSGSA 290
++KPI+ +E +++++ K + + +Q + LE+ ++L G
Sbjct: 1313 EKKPIFIQEGAIREDMIQGVTQEVIRHKEVMPREEEQAQKKARDMLGLEETQVILKKGKK 1372
Query: 291 -----EGSLQKAEKVLKKVLEWNKEEVPNKDELVGNLYSCIGNAQIELGQMEAALQSHRK 345
G++ +++ KK + ++ P + +G + E+ + E + +
Sbjct: 1373 VIFLEPGNVTMGKEISKKEEKKTFQKSPKQGRKAVQKERKVGKIKREMTKEERDMSEEVE 1432
Query: 346 DLEIAKEYDLPDAKSRALDNIGRV--FARVGKFQQAIDTWEEKIPLAKTTLE--KTWLFH 401
++ +E + + G++ R +Q W+E + T + K W
Sbjct: 1433 EMATLEE--------KVVKQEGKLVMIERTPSWQDWKKAWDEWKQVHGETRKSWKAWKEE 1484
Query: 402 EIGRCYLELDQAWQAQNYGEKSQQCAEEEGDIEWQLNASVLVAQAQVKLRDFESAVNNFE 461
R E ++ QA ++ +E+ ++W+ V K ++ + + E
Sbjct: 1485 WEKRLLQEEEKLHQAGEKLSPEEEMLQEDKKLKWEEWKQVWENMLSSKSKE-QQYKDEEE 1543
Query: 462 KALERAKLVHNNEAQQAIISA---LDDANKGIIRELRKTNYVENLKEKSEGEASLYEDRI 518
LE E +Q + + + +K R RK E + + E + + E+++
Sbjct: 1544 VTLEEEVSREGEEKEQQVTEEQRHIQEEHKWA-RIHRKRARAEKKRAQEERKLAQEEEKL 1602
Query: 519 ITREKDMRRVRDEPEKVVKQWDH-SEDEKETDEDDEAFGEALQSPASG--KQSVEAGKAR 575
E R++ E K+ + + ++D++E + + F + ++ A K S EA K
Sbjct: 1603 AQEE---RQLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRGEKLSQEAEKLA 1659
Query: 576 SDLGAVAKGLS--GELGTRSGETGRKLLEAGRRESREIYRRPSGELEQRLSGEFSRQEPE 633
+AK + + G KL E ++++ P E + QE E
Sbjct: 1660 QKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNLDWQEKELAQELE 1719
Query: 634 ELKKLSEVGRREPEELGKTQFGEIGETKKTGNEME 668
EL+ E + EEL + + + E KK E E
Sbjct: 1720 ELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEE 1754
>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
sapiens]
Length = 1937
Score = 43.5 bits (101), Expect = 6e-04
Identities = 123/535 (22%), Positives = 203/535 (37%), Gaps = 94/535 (17%)
Query: 178 KASLKSEKTVRQLLGELYVDKEYLEKLLLDEDLIKGTMKGGLTVEDLIMTGINYLDTHSN 237
KA K E+ V L G L +K KL +D + K ++G DL + + +D ++
Sbjct: 1025 KAKTKLEQQVDDLEGSLEQEK----KLRMDLERAKRKLEG-----DLKLAQESTMDMEND 1075
Query: 238 FWRQQKPIYARERDRKLMQEKWLRDHKRRPSQTAHYILKSLEDIDMLLTSGSAE-GSLQK 296
+ + + +E + + K + D + Q I + I+ L AE S K
Sbjct: 1076 KQQLDEKLEKKEFEISNLISK-IEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAK 1134
Query: 297 AEKVLKKVLEWNKEEVPNKDELVGNLYSCIGNAQIELGQM-EAALQSHRKDLEIA----- 350
AEK + L EE+ + E G S AQ+EL + EA Q R+DLE A
Sbjct: 1135 AEKQ-RSDLSRELEEISERLEEAGGATS----AQVELNKKREAEFQKLRRDLEEATLQHE 1189
Query: 351 --------KEYDLPDAKSRALDNIGRVFARVGKFQQAI-------DTWEEKIPLAKTTLE 395
K D +DN+ RV ++ K + + + E I AK LE
Sbjct: 1190 AMVAALRKKHADSMAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLE 1249
Query: 396 KTWLFHEIGRCYLELDQAWQAQ--------------NYGEKSQQCAEEEGDIEWQLNASV 441
K E L+ + Q + GE S+Q E++ + QL+ S
Sbjct: 1250 KMCRSLEDQVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVS-QLSRSK 1308
Query: 442 LVAQAQVK-----LRDFESAVNNFEKALE---------RAKLVHNNEAQQAIISALDDAN 487
+ Q++ L + A N AL+ R + E + + AL AN
Sbjct: 1309 QASTQQIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKAN 1368
Query: 488 KGIIR--------ELRKTNYVENLKEK-------SEGEASLYEDRIITREKDMRRVRDEP 532
+ + +++T +E K+K +E + + EK +R+++E
Sbjct: 1369 SEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEV 1428
Query: 533 EKVVKQWDHSED-----EKETDEDDEAFGEALQSPASGKQSVEAGKARSDLGAVAKGLSG 587
E ++ + S +K+ D+ E Q + +EA + S + LS
Sbjct: 1429 EDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQAELEASQKES------RSLST 1482
Query: 588 ELGTRSG--ETGRKLLEAGRRESREIYRRPSGELEQRLSGEFSRQEPEELKKLSE 640
EL E LE RRE++ + + S EQ G E E++KK E
Sbjct: 1483 ELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIAEGGKQIHELEKIKKQVE 1537
Score = 41.6 bits (96), Expect = 0.002
Identities = 80/404 (19%), Positives = 162/404 (40%), Gaps = 49/404 (12%)
Query: 294 LQKAEKVLKKVLEWNKEEVPNKDELVGNLYSCIGNAQIELGQMEAALQSHRKDLEIAKEY 353
L K+ + K++ +E KDEL + + EL + L + DL++ +
Sbjct: 842 LLKSAETEKEMATMKEEFQKTKDELAKSEAK-----RKELEEKMVTLLKEKNDLQLQVQS 896
Query: 354 D---LPDAKSRALDNIGRVFARVGKFQQAIDTWEEKIPL-AKTTLEKTWLFHEIGRCYLE 409
+ L DA+ R I K ++ + EE+ + A+ T +K L E +
Sbjct: 897 EADSLADAEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKD 956
Query: 410 LDQAWQAQNYGEKSQQCAEEEGDIEWQLNASV------LVAQAQVKLRDFESAVNNFEKA 463
+D EK + E + + A + L + + + +++ +
Sbjct: 957 IDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAE 1016
Query: 464 LERAKLVHNNEAQQAIISALDDANKGIIRELRKTNYVENLKEKSEGEASLYEDRIITREK 523
++ ++ +A+ + +DD + +E + +E K K EG+ L ++ + E
Sbjct: 1017 EDKVNIL--TKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMEN 1074
Query: 524 DMRRVRDEPEKVVKQWDHS------EDE-----------KETDEDDEAFGEALQSPASGK 566
D +++ ++ EK K+++ S EDE KE E GE +++ + +
Sbjct: 1075 DKQQLDEKLEK--KEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASR 1132
Query: 567 QSVEAGKARSDLGAVAKGLSGELGTRSGETGRKLLEAGRRESREIYRRPSGELEQRLSGE 626
E K RSDL + +S L G T ++ +RE+ +++ +LE E
Sbjct: 1133 AKAE--KQRSDLSRELEEISERLEEAGGATSAQVELNKKREAE--FQKLRRDLE-----E 1183
Query: 627 FSRQEPEELKKLSEVGRREPEELGKTQFGEIGETKKTGNEMEKE 670
+ Q + L + ELG+ +I ++ ++EKE
Sbjct: 1184 ATLQHEAMVAALRKKHADSMAELGE----QIDNLQRVKQKLEKE 1223
Score = 31.6 bits (70), Expect = 2.5
Identities = 55/271 (20%), Positives = 110/271 (40%), Gaps = 53/271 (19%)
Query: 409 ELDQAWQAQNYGEKSQQCAEEEGDIEWQLNASVLVAQAQVKLRDFESAVNNFEKALERAK 468
E+++ W E+S++ AE+E +L A +V+L +
Sbjct: 1687 EIEELWATLEQTERSRKIAEQE----------LLDASERVQLLH-----------TQNTS 1725
Query: 469 LVHNNEAQQAIISALDDANKGIIRELRKTNYVENLKEKSEGEASLYEDRIITREKD---- 524
L++ + + +S L + +I+E R N E K+ A + E+ + +E+D
Sbjct: 1726 LINTKKKLENDVSQLQSEVEEVIQESR--NAEEKAKKAITDAAMMAEE--LKKEQDTSAH 1781
Query: 525 MRRVRDEPEKVVKQWDHSEDEKETDEDDEAFGEALQSPASGKQSVEAGKARSDLGAVAKG 584
+ R++ E+ VK H DE E + GK+ ++ +AR +
Sbjct: 1782 LERMKKNLEQTVKDLQHRLDEAEQ-----------LALKGGKKQIQKLEAR------VRE 1824
Query: 585 LSGELGT---RSGETGRKLLEAGRRESREIYRRPSGELEQRLSGEFSRQEPEELKKLSEV 641
L GE+ R+ E + L + RR Y+ E R + + ++L+ +
Sbjct: 1825 LEGEVENEQKRNAEAVKGLRKHERRVKELTYQTE----EDRKNVLRLQDLVDKLQAKVKS 1880
Query: 642 GRREPEELGKTQFGEIGETKKTGNEMEKEYE 672
+R+ EE + + + +K +E+E+ E
Sbjct: 1881 YKRQAEEAEEQSNANLSKFRKLQHELEEAEE 1911
>gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo
sapiens]
Length = 1939
Score = 43.5 bits (101), Expect = 6e-04
Identities = 96/452 (21%), Positives = 174/452 (38%), Gaps = 74/452 (16%)
Query: 243 KPIYARERDRKLMQEKWLRDHKRRPSQTAHYILKSLEDIDMLLTSGSAEGSLQKAEKVLK 302
K + R D + + + L KR+ + K ++D++ LT E E +K
Sbjct: 924 KEVTERAEDEEEINAE-LTAKKRKLEDECSELKKDIDDLE--LTLAKVEKEKHATENKVK 980
Query: 303 KVLEWNKEEVPNKDELVGNLYSCIGNAQIELGQMEAALQSHRKDLEIAKEYDLPDAKSRA 362
+ E E+ DE + A L +K L+ A + L D +
Sbjct: 981 NLTE----EMAGLDETI------------------AKLTKEKKALQEAHQQTLDDLQMEE 1018
Query: 363 LDNIGRVFARVGKFQQAIDTWE-----EK-----IPLAKTTLEKTWLFHEIGRCYLELDQ 412
D + + K +Q +D E EK + AK LE + E D+
Sbjct: 1019 -DKVNTLTKAKTKLEQQVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQESTMDTENDK 1077
Query: 413 AWQAQNYGEKSQQCAEEEGDIEWQLNASVLVAQAQVKLRDFESAVNNFEKALERAKLVHN 472
+ +K + + +G IE + L Q Q K+++ ++ + E+ +E
Sbjct: 1078 QQLNEKLKKKEFEMSNLQGKIE---DEQALAIQLQKKIKELQARIEELEEEIE------- 1127
Query: 473 NEAQQAIISALDDANKGIIRELRKTNYVENLKEKSEGEASLYEDRIITREKDMRRVRDEP 532
A++A + + + REL + + E++ G S + RE + +++R +
Sbjct: 1128 --AERASRAKAEKQRSDLSRELEE---ISERLEEAGGATSAQIEMNKKREAEFQKMRRDL 1182
Query: 533 EKVVKQWDHSEDEKETDEDDEA--FGEALQSPASGKQSVEAGKAR---------SDLGAV 581
E+ Q + + D GE + S KQ +E K+ S++ V
Sbjct: 1183 EESTLQHEATAAALRKKHADSVAELGEQIDSLQRVKQKLEKEKSELKMEINDLASNMETV 1242
Query: 582 AKGLSG-ELGTRSGETGRKLLEAGRRESREIYRRPSGELEQRL---SGEFSRQEPEELKK 637
+K + E R+ E ++ E + + S + + RL SGEFSRQ E+
Sbjct: 1243 SKAKANFEKMCRTLEDQLSEIKTKEEEQQRLINELSAQ-KARLHTESGEFSRQLDEKDAM 1301
Query: 638 LSEVGR------REPEELGKTQFGEIGETKKT 663
+S++ R ++ EEL K Q E + K T
Sbjct: 1302 VSQLSRGKQAFTQQIEEL-KRQLEEETKAKST 1332
Score = 40.0 bits (92), Expect = 0.007
Identities = 80/399 (20%), Positives = 157/399 (39%), Gaps = 39/399 (9%)
Query: 294 LQKAEKVLKKVLEWNKEEVPNKDELVGNLYSCIGNAQIELGQMEAALQSHRKDLEIAKEY 353
L K+ + K++ +E K+EL + EL + L + DL++ +
Sbjct: 843 LLKSAETEKEMANMKEEFEKTKEELAKTEAK-----RKELEEKMVTLMQEKNDLQLQVQA 897
Query: 354 D---LPDAKSRALDNIGRVFARVGKFQQAIDTWEEKIPL-AKTTLEKTWLFHEIGRCYLE 409
+ L DA+ R I K ++ + E++ + A+ T +K L E +
Sbjct: 898 EADALADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKD 957
Query: 410 LDQAWQAQNYGEKSQQCAEEEGD--IEWQLNASVLVAQAQVKLRDFESAVNNF--EKALE 465
+D EK + E + E +A+ + + + A + +E
Sbjct: 958 IDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQME 1017
Query: 466 RAKLVHNNEAQQAIISALDDANKGIIRELRKTNYVENLKEKSEGEASLYEDRIITREKDM 525
K+ +A+ + +DD + +E + +E K K EG+ L ++ + E D
Sbjct: 1018 EDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQESTMDTENDK 1077
Query: 526 RRVRDEPEKVVKQWDHSEDEKETDEDDEAFGEALQSPASGKQS--------VEAGKARSD 577
+++ ++ +K K+++ S + + ED++A LQ Q+ +EA +A
Sbjct: 1078 QQLNEKLKK--KEFEMSNLQGKI-EDEQALAIQLQKKIKELQARIEELEEEIEAERASR- 1133
Query: 578 LGAVAKGLSGELGTRSGETGRKLLEAGRRESREIYRRPSGELEQRLSGEFS--RQEPEEL 635
A A+ +L E +L EAG S +I E+ ++ EF R++ EE
Sbjct: 1134 --AKAEKQRSDLSRELEEISERLEEAGGATSAQI------EMNKKREAEFQKMRRDLEES 1185
Query: 636 KKLSEVGRREPEELGKTQFGEIGE----TKKTGNEMEKE 670
E + E+GE ++ ++EKE
Sbjct: 1186 TLQHEATAAALRKKHADSVAELGEQIDSLQRVKQKLEKE 1224
Score = 29.6 bits (65), Expect = 9.5
Identities = 70/331 (21%), Positives = 135/331 (40%), Gaps = 50/331 (15%)
Query: 339 ALQSHRKDLEIAKEY--DLPDAKSRALDNIGRVFARVGKFQQAIDTWEEKIPLAKTTLEK 396
ALQS R D ++ +E + +AK+ + + + V +++ +T + T E
Sbjct: 1336 ALQSARHDCDLLREQYEEEQEAKAELQRGMSKANSEVAQWRTKYET-----DAIQRTEEL 1390
Query: 397 TWLFHEIGRCYLELDQAWQAQNYG----EKSQQCAEEEGDIEWQLNASVLVAQAQVKLRD 452
++ + + ++ +A N EK++Q + E + + + V ++
Sbjct: 1391 EEAKKKLAQRLQDAEEHVEAVNSKCASLEKTKQRLQNEVE-----DLMIDVERSNAACIA 1445
Query: 453 FESAVNNFEKALERAKLVHNNEAQQAIISALDDANKGIIRELRKT--------NYVENLK 504
+ NF+K L K + E QA + A ++ + EL K +++E LK
Sbjct: 1446 LDKKQRNFDKVLAEWKQKY--EETQAELEASQKESRSLSTELFKVKNAYEESLDHLETLK 1503
Query: 505 EKSEG---EASLYEDRIITREKDMRRVRDEPEKVVKQWDHSEDEKETDEDDEAFGEALQS 561
+++ E S ++I K + E EKV KQ DH + E +T ++ EA
Sbjct: 1504 RENKNLQQEISDLTEQIAEGGKHIH----ELEKVKKQLDHEKSELQTSLEE---AEASLE 1556
Query: 562 PASGK---QSVEAGKARSDLGAVAKGLSGELG------TRSGETGRKLLEA---GRRESR 609
GK +E + +S++ EL R E+ + L+A R ++
Sbjct: 1557 HEEGKILRIQLELNQVKSEIDRKIAEKDEELDQLKRNHLRVVESMQSTLDAEIRSRNDAL 1616
Query: 610 EIYRRPSGELEQR--LSGEFSRQEPEELKKL 638
I ++ G+L + +RQ E L+ L
Sbjct: 1617 RIKKKMEGDLNEMEIQLNHANRQAAEALRNL 1647
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 43.1 bits (100), Expect = 8e-04
Identities = 74/423 (17%), Positives = 165/423 (39%), Gaps = 80/423 (18%)
Query: 239 WRQQKPIYARERDRKLMQEKWLRDHKRRPSQTAHYILKSLEDIDMLLTSGSAEGSLQKAE 298
W Q+K ++ +E+ R+ + W ++ K R + + E +K +
Sbjct: 527 WGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMW--------------DQEERMEKKTQ 572
Query: 299 KVLKKVLEWNKEEVPNKDELVGNLYSCIGNAQIELGQMEAALQSHRKDLEIAKEYDLPDA 358
+ KK W++EE ++E + + + + + E +Q + ++ +E + +
Sbjct: 573 EQEKKT--WDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQ-EQEEKMWEQ 629
Query: 359 KSRALDNIGRVFARVGK-FQQAIDTWE-EKIPLAKTTLEKTWLFHEIGRCYLELDQAWQA 416
+ + + +++ + K ++Q WE +++P K L + E + + ++ W+
Sbjct: 630 EEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQ 689
Query: 417 QNYGEKSQQCAEEEGDIEWQLNASVLVAQAQVKLRDFESAVNNFEKALERAKLVHNNEAQ 476
+ +K+Q+ ++ D Q K+R+ ES +K E +++ E
Sbjct: 690 EKMEKKTQEQEKKTWD--------------QEKMREEESMREREKKMREEEEMMREQE-- 733
Query: 477 QAIISALDDANKGIIRELRKTNYVENLKEKSEGEASLYEDRIITREKDMRRVRDEPEKVV 536
K E ++ E E E+++ +E+ M + PE+
Sbjct: 734 ------------------EKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKE 775
Query: 537 KQWDH----------SEDEKETDEDDEAFGEALQSPASGKQSVEAGKARSDLGAVAKGLS 586
K W+H ++EK D++++ G+ + G++ G+ G K
Sbjct: 776 KLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQ--EEKMRGQEEKMRGQEEKMWGQEEK--- 830
Query: 587 GELGTRSGETGRKLLEAGRRESREIYRRPSGELEQRLSG-EFSRQEPEELKKLSEVGRRE 645
G G++ G+ E ++E+++ G E +E EE + E RE
Sbjct: 831 -MWGQEEKMWGQEEKMWGQEE----------KMEEKMQGQEEKMREQEEKMRGQEEKMRE 879
Query: 646 PEE 648
EE
Sbjct: 880 QEE 882
Score = 40.0 bits (92), Expect = 0.007
Identities = 73/436 (16%), Positives = 160/436 (36%), Gaps = 89/436 (20%)
Query: 239 WRQQKPIYARERDRKLMQEKWLRDHKRRPSQTAHYILKSLEDIDMLLTSGSAEGSLQKAE 298
WRQ++ + +E+ + +EK R +R Q EG +++ E
Sbjct: 275 WRQEEELREQEKKIRKQEEKMWRQEERLREQ---------------------EGKMREQE 313
Query: 299 KVLKKVLEWNKEEVPNKDELVGNLYSCIGNAQIELGQMEAALQSHRKDLEIAKEYDLPDA 358
+ + W +E+ L + E L+ K+L KE +
Sbjct: 314 EKM-----WRQEK--------------------RLREQEKELREQEKELREQKELREQEE 348
Query: 359 KSRALDNIGRVFARVGKFQQAIDTWEEKIPLAKTTLEKTWLFHEIGRCYLELDQAWQAQN 418
+ + +Q WE++ + + EK W E + W+ +
Sbjct: 349 QMQ---------------EQEEKMWEQEEKMREQE-EKMWRQEE---------RLWEQEK 383
Query: 419 YGEKSQQCAEEEGDIEWQLNASVLVAQAQVKLRDFESAVNNFEKALERAKLVHNNEAQQA 478
+ +Q ++ + W+ + + + + ++R+ E EK E K+ + +
Sbjct: 384 QMREQEQKMRDQEERMWEQDER--LREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRD 441
Query: 479 IISALDDANKGIIRELRKTNYVENLKEKSEGEASLYEDRIITREKD--MRRVRDEPEKVV 536
+ + + RE + E ++E+ E E+ EK+ +R+ ++ EK+
Sbjct: 442 QEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLW 501
Query: 537 KQWDHSEDEKETDEDDEAFGEALQSPASGKQSVEAGKARSDLGAVAKGLSGELGTRSGET 596
+Q E E++ E +E + + K+ K R E + E
Sbjct: 502 EQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMR------------EQEDQMWEQ 549
Query: 597 GRKLLEAGRR--ESREIYRRPSGELEQRLSGEFSRQEPEELKKLSEVGRREPEELGKTQF 654
K+ + ++ + E + + E E++ + + EE + E RE EE+ + Q
Sbjct: 550 EEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQE 609
Query: 655 GEIGETKKTGNEMEKE 670
++ E ++ E E++
Sbjct: 610 EKMQEQEEKMQEQEEK 625
Score = 38.9 bits (89), Expect = 0.016
Identities = 84/464 (18%), Positives = 181/464 (39%), Gaps = 51/464 (10%)
Query: 233 DTHSNFWRQQKPIYARERDRKLM-QEKWLRDHKRRPSQTAHYILKSLEDIDMLLTSGSAE 291
+ WRQ+K + RE++++L QEK LR+ K Q + + + E
Sbjct: 311 EQEEKMWRQEKRL--REQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQE 368
Query: 292 GSLQKAEKVL---KKVLEWNKEEVPNKDELVGNLYSCIGNAQIELGQMEAA---LQSHRK 345
+ + E+ L +K + ++++ +++E + + + + + E ++ R+
Sbjct: 369 EKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMRE 428
Query: 346 DLEIAKEYDLPDAKSRALDNIGRVFARVGKFQQAIDTWEEKIPLAKTTLEKTWLFHEIGR 405
+ ++ ++ + + R+ R K ++ +T E+ + E W E
Sbjct: 429 EKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEE--- 485
Query: 406 CYLELDQAWQAQNYGEKSQQCAEEEGDIEWQLNASVLVAQAQVKLRDFESAVNNFEKALE 465
+ WQ Q E+ ++ E+E E + + + + K+RD E +K
Sbjct: 486 ------KEWQQQRLPEQKEKLWEQEKMQEQEEK----IWEQEEKIRDQEEMWGQEKKMWR 535
Query: 466 RAKLVHNNEAQQAIISALDDANKGIIRE---LRKTNYVENLKEKSEGEASLYEDRIITRE 522
+ K+ + + D + + + + K + K + E E+R+ RE
Sbjct: 536 QEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMRERE 595
Query: 523 KDMRR----VRDEPEKVVKQWDHSEDEKETDEDDEAFGEALQSPASGKQSVEAGKARSDL 578
K MR +R++ EK+ E E++ E +E E Q +Q + + +
Sbjct: 596 KKMREEEEMMREQEEKM------QEQEEKMQEQEEKMWE--QEEKMQEQEEKMWEQEEKM 647
Query: 579 GAVAKGLSGELGTRSGETGRKLLEAGRRESREIYRRPSGELEQRLSGEFSRQEPE----- 633
+ + + R E KL E + + +E + ++ ++ E QE E
Sbjct: 648 WEQEEKMWEQ--QRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWD 705
Query: 634 -------ELKKLSEVGRREPEELGKTQFGEIGETKKTGNEMEKE 670
E + E RE EE+ + Q ++ E ++ E E+E
Sbjct: 706 QEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEE 749
>gi|4506921 small glutamine-rich tetratricopeptide [Homo sapiens]
Length = 313
Score = 43.1 bits (100), Expect = 8e-04
Identities = 39/157 (24%), Positives = 67/157 (42%), Gaps = 15/157 (9%)
Query: 18 AEGERLYLCGE-------FSKAAQSFSNALYLQDGDKNCLVARSKCFLKMGDLERSLKDA 70
AE ERL G F A + A+ L + R+ + K+G+ +++D
Sbjct: 89 AEAERLKTEGNEQMKVENFEAAVHFYGKAIELNPANAVYFCNRAAAYSKLGNYAGAVQDC 148
Query: 71 EASLQSDPAFCKGILQKAETLYTMGDFEFALVFYHRGYKLRPDRE-----FRVGIQKAQE 125
E ++ DPA+ K + L ++ A+ +Y + +L PD E ++ K +E
Sbjct: 149 ERAICIDPAYSKAYGRMGLALSSLNKHVEAVAYYKKALELDPDNETYKSNLKIAELKLRE 208
Query: 126 AINNSVGSPS---SIKLENKGDLSFLSKQAENIKAQQ 159
A + + G S + L N G +S S N + QQ
Sbjct: 209 APSPTGGVGSFDIAGLLNNPGFMSMASNLMNNPQIQQ 245
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.130 0.366
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,816,018
Number of Sequences: 37866
Number of extensions: 1155853
Number of successful extensions: 5822
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 56
Number of HSP's successfully gapped in prelim test: 317
Number of HSP's that attempted gapping in prelim test: 5142
Number of HSP's gapped (non-prelim): 876
length of query: 672
length of database: 18,247,518
effective HSP length: 109
effective length of query: 563
effective length of database: 14,120,124
effective search space: 7949629812
effective search space used: 7949629812
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.