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Search of human proteins with 13677222
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|13677222 receptor-type protein tyrosine phosphatase O
isoform c precursor [Homo sapiens]
(405 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|13677222 receptor-type protein tyrosine phosphatase O isoform... 833 0.0
gi|13677218 receptor-type protein tyrosine phosphatase O isoform... 833 0.0
gi|13677214 receptor-type protein tyrosine phosphatase O isoform... 833 0.0
gi|13677220 receptor-type protein tyrosine phosphatase O isoform... 758 0.0
gi|13677216 receptor-type protein tyrosine phosphatase O isoform... 758 0.0
gi|4506323 receptor-type protein tyrosine phosphatase O isoform ... 758 0.0
gi|157952215 protein tyrosine phosphatase, receptor type, B isof... 297 1e-80
gi|157952213 protein tyrosine phosphatase, receptor type, B isof... 297 1e-80
gi|222537743 protein tyrosine phosphatase, receptor type, Q [Hom... 283 3e-76
gi|148728162 protein tyrosine phosphatase, receptor type, J isof... 278 6e-75
gi|241896926 protein tyrosine phosphatase, receptor type, H isof... 268 5e-72
gi|241896924 protein tyrosine phosphatase, receptor type, H isof... 268 5e-72
gi|109633041 protein tyrosine phosphatase, receptor type, F isof... 225 5e-59
gi|109633039 protein tyrosine phosphatase, receptor type, F isof... 225 5e-59
gi|104487611 protein tyrosine phosphatase, receptor type, sigma ... 223 2e-58
gi|104487297 protein tyrosine phosphatase, receptor type, sigma ... 223 2e-58
gi|104487295 protein tyrosine phosphatase, receptor type, sigma ... 223 2e-58
gi|104487006 protein tyrosine phosphatase, receptor type, sigma ... 223 2e-58
gi|104487002 protein tyrosine phosphatase, receptor type, D isof... 223 2e-58
gi|4506309 protein tyrosine phosphatase, receptor type, D isofor... 223 2e-58
gi|18860890 protein tyrosine phosphatase, receptor type, D isofo... 223 2e-58
gi|18860892 protein tyrosine phosphatase, receptor type, D isofo... 223 2e-58
gi|18860894 protein tyrosine phosphatase, receptor type, D isofo... 223 2e-58
gi|148539860 protein tyrosine phosphatase, receptor type, T isof... 222 4e-58
gi|148539858 protein tyrosine phosphatase, receptor type, T isof... 222 4e-58
gi|157419150 protein tyrosine phosphatase, receptor type, M isof... 219 3e-57
gi|157419152 protein tyrosine phosphatase, receptor type, M isof... 219 3e-57
gi|18641364 protein tyrosine phosphatase, receptor type, C isofo... 216 4e-56
gi|18641347 protein tyrosine phosphatase, receptor type, C isofo... 216 4e-56
gi|18641362 protein tyrosine phosphatase, receptor type, C isofo... 216 4e-56
>gi|13677222 receptor-type protein tyrosine phosphatase O isoform c
precursor [Homo sapiens]
Length = 405
Score = 833 bits (2152), Expect = 0.0
Identities = 405/405 (100%), Positives = 405/405 (100%)
Query: 1 MVTEMNPNVVVISVLAILSTLLIGLLLVTLIILRKKHLQMARECGAGTFVNFASLERDGK 60
MVTEMNPNVVVISVLAILSTLLIGLLLVTLIILRKKHLQMARECGAGTFVNFASLERDGK
Sbjct: 1 MVTEMNPNVVVISVLAILSTLLIGLLLVTLIILRKKHLQMARECGAGTFVNFASLERDGK 60
Query: 61 LPYNWRRSIFAFLTLLPSCLWTDYLLAFYINPWSKNGLKKRKLTNPVQLDDFDAYIKDMA 120
LPYNWRRSIFAFLTLLPSCLWTDYLLAFYINPWSKNGLKKRKLTNPVQLDDFDAYIKDMA
Sbjct: 61 LPYNWRRSIFAFLTLLPSCLWTDYLLAFYINPWSKNGLKKRKLTNPVQLDDFDAYIKDMA 120
Query: 121 KDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGAD 180
KDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGAD
Sbjct: 121 KDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGAD 180
Query: 181 YINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYW 240
YINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYW
Sbjct: 181 YINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYW 240
Query: 241 PFTEEPIAYGDITVEMISEEEQDDWACRHFRINYADEMQDVMHFNYTAWPDHGVPTANAA 300
PFTEEPIAYGDITVEMISEEEQDDWACRHFRINYADEMQDVMHFNYTAWPDHGVPTANAA
Sbjct: 241 PFTEEPIAYGDITVEMISEEEQDDWACRHFRINYADEMQDVMHFNYTAWPDHGVPTANAA 300
Query: 301 ESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEM 360
ESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEM
Sbjct: 301 ESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEM 360
Query: 361 RSYRMSMVQTEEQYIFIHQCVQLMWMKKKQQFCISDVIYENVSKS 405
RSYRMSMVQTEEQYIFIHQCVQLMWMKKKQQFCISDVIYENVSKS
Sbjct: 361 RSYRMSMVQTEEQYIFIHQCVQLMWMKKKQQFCISDVIYENVSKS 405
>gi|13677218 receptor-type protein tyrosine phosphatase O isoform c
precursor [Homo sapiens]
Length = 405
Score = 833 bits (2152), Expect = 0.0
Identities = 405/405 (100%), Positives = 405/405 (100%)
Query: 1 MVTEMNPNVVVISVLAILSTLLIGLLLVTLIILRKKHLQMARECGAGTFVNFASLERDGK 60
MVTEMNPNVVVISVLAILSTLLIGLLLVTLIILRKKHLQMARECGAGTFVNFASLERDGK
Sbjct: 1 MVTEMNPNVVVISVLAILSTLLIGLLLVTLIILRKKHLQMARECGAGTFVNFASLERDGK 60
Query: 61 LPYNWRRSIFAFLTLLPSCLWTDYLLAFYINPWSKNGLKKRKLTNPVQLDDFDAYIKDMA 120
LPYNWRRSIFAFLTLLPSCLWTDYLLAFYINPWSKNGLKKRKLTNPVQLDDFDAYIKDMA
Sbjct: 61 LPYNWRRSIFAFLTLLPSCLWTDYLLAFYINPWSKNGLKKRKLTNPVQLDDFDAYIKDMA 120
Query: 121 KDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGAD 180
KDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGAD
Sbjct: 121 KDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGAD 180
Query: 181 YINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYW 240
YINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYW
Sbjct: 181 YINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYW 240
Query: 241 PFTEEPIAYGDITVEMISEEEQDDWACRHFRINYADEMQDVMHFNYTAWPDHGVPTANAA 300
PFTEEPIAYGDITVEMISEEEQDDWACRHFRINYADEMQDVMHFNYTAWPDHGVPTANAA
Sbjct: 241 PFTEEPIAYGDITVEMISEEEQDDWACRHFRINYADEMQDVMHFNYTAWPDHGVPTANAA 300
Query: 301 ESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEM 360
ESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEM
Sbjct: 301 ESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEM 360
Query: 361 RSYRMSMVQTEEQYIFIHQCVQLMWMKKKQQFCISDVIYENVSKS 405
RSYRMSMVQTEEQYIFIHQCVQLMWMKKKQQFCISDVIYENVSKS
Sbjct: 361 RSYRMSMVQTEEQYIFIHQCVQLMWMKKKQQFCISDVIYENVSKS 405
>gi|13677214 receptor-type protein tyrosine phosphatase O isoform a
precursor [Homo sapiens]
Length = 1216
Score = 833 bits (2152), Expect = 0.0
Identities = 405/405 (100%), Positives = 405/405 (100%)
Query: 1 MVTEMNPNVVVISVLAILSTLLIGLLLVTLIILRKKHLQMARECGAGTFVNFASLERDGK 60
MVTEMNPNVVVISVLAILSTLLIGLLLVTLIILRKKHLQMARECGAGTFVNFASLERDGK
Sbjct: 812 MVTEMNPNVVVISVLAILSTLLIGLLLVTLIILRKKHLQMARECGAGTFVNFASLERDGK 871
Query: 61 LPYNWRRSIFAFLTLLPSCLWTDYLLAFYINPWSKNGLKKRKLTNPVQLDDFDAYIKDMA 120
LPYNWRRSIFAFLTLLPSCLWTDYLLAFYINPWSKNGLKKRKLTNPVQLDDFDAYIKDMA
Sbjct: 872 LPYNWRRSIFAFLTLLPSCLWTDYLLAFYINPWSKNGLKKRKLTNPVQLDDFDAYIKDMA 931
Query: 121 KDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGAD 180
KDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGAD
Sbjct: 932 KDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGAD 991
Query: 181 YINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYW 240
YINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYW
Sbjct: 992 YINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYW 1051
Query: 241 PFTEEPIAYGDITVEMISEEEQDDWACRHFRINYADEMQDVMHFNYTAWPDHGVPTANAA 300
PFTEEPIAYGDITVEMISEEEQDDWACRHFRINYADEMQDVMHFNYTAWPDHGVPTANAA
Sbjct: 1052 PFTEEPIAYGDITVEMISEEEQDDWACRHFRINYADEMQDVMHFNYTAWPDHGVPTANAA 1111
Query: 301 ESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEM 360
ESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEM
Sbjct: 1112 ESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEM 1171
Query: 361 RSYRMSMVQTEEQYIFIHQCVQLMWMKKKQQFCISDVIYENVSKS 405
RSYRMSMVQTEEQYIFIHQCVQLMWMKKKQQFCISDVIYENVSKS
Sbjct: 1172 RSYRMSMVQTEEQYIFIHQCVQLMWMKKKQQFCISDVIYENVSKS 1216
>gi|13677220 receptor-type protein tyrosine phosphatase O isoform d
precursor [Homo sapiens]
Length = 377
Score = 758 bits (1956), Expect = 0.0
Identities = 377/405 (93%), Positives = 377/405 (93%), Gaps = 28/405 (6%)
Query: 1 MVTEMNPNVVVISVLAILSTLLIGLLLVTLIILRKKHLQMARECGAGTFVNFASLERDGK 60
MVTEMNPNVVVISVLAILSTLLIGLLLVTLIILRKKHLQMARECGAGTFVNFASLERDGK
Sbjct: 1 MVTEMNPNVVVISVLAILSTLLIGLLLVTLIILRKKHLQMARECGAGTFVNFASLERDGK 60
Query: 61 LPYNWRRSIFAFLTLLPSCLWTDYLLAFYINPWSKNGLKKRKLTNPVQLDDFDAYIKDMA 120
LPYNW SKNGLKKRKLTNPVQLDDFDAYIKDMA
Sbjct: 61 LPYNW----------------------------SKNGLKKRKLTNPVQLDDFDAYIKDMA 92
Query: 121 KDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGAD 180
KDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGAD
Sbjct: 93 KDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGAD 152
Query: 181 YINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYW 240
YINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYW
Sbjct: 153 YINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYW 212
Query: 241 PFTEEPIAYGDITVEMISEEEQDDWACRHFRINYADEMQDVMHFNYTAWPDHGVPTANAA 300
PFTEEPIAYGDITVEMISEEEQDDWACRHFRINYADEMQDVMHFNYTAWPDHGVPTANAA
Sbjct: 213 PFTEEPIAYGDITVEMISEEEQDDWACRHFRINYADEMQDVMHFNYTAWPDHGVPTANAA 272
Query: 301 ESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEM 360
ESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEM
Sbjct: 273 ESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEM 332
Query: 361 RSYRMSMVQTEEQYIFIHQCVQLMWMKKKQQFCISDVIYENVSKS 405
RSYRMSMVQTEEQYIFIHQCVQLMWMKKKQQFCISDVIYENVSKS
Sbjct: 333 RSYRMSMVQTEEQYIFIHQCVQLMWMKKKQQFCISDVIYENVSKS 377
>gi|13677216 receptor-type protein tyrosine phosphatase O isoform d
precursor [Homo sapiens]
Length = 377
Score = 758 bits (1956), Expect = 0.0
Identities = 377/405 (93%), Positives = 377/405 (93%), Gaps = 28/405 (6%)
Query: 1 MVTEMNPNVVVISVLAILSTLLIGLLLVTLIILRKKHLQMARECGAGTFVNFASLERDGK 60
MVTEMNPNVVVISVLAILSTLLIGLLLVTLIILRKKHLQMARECGAGTFVNFASLERDGK
Sbjct: 1 MVTEMNPNVVVISVLAILSTLLIGLLLVTLIILRKKHLQMARECGAGTFVNFASLERDGK 60
Query: 61 LPYNWRRSIFAFLTLLPSCLWTDYLLAFYINPWSKNGLKKRKLTNPVQLDDFDAYIKDMA 120
LPYNW SKNGLKKRKLTNPVQLDDFDAYIKDMA
Sbjct: 61 LPYNW----------------------------SKNGLKKRKLTNPVQLDDFDAYIKDMA 92
Query: 121 KDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGAD 180
KDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGAD
Sbjct: 93 KDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGAD 152
Query: 181 YINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYW 240
YINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYW
Sbjct: 153 YINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYW 212
Query: 241 PFTEEPIAYGDITVEMISEEEQDDWACRHFRINYADEMQDVMHFNYTAWPDHGVPTANAA 300
PFTEEPIAYGDITVEMISEEEQDDWACRHFRINYADEMQDVMHFNYTAWPDHGVPTANAA
Sbjct: 213 PFTEEPIAYGDITVEMISEEEQDDWACRHFRINYADEMQDVMHFNYTAWPDHGVPTANAA 272
Query: 301 ESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEM 360
ESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEM
Sbjct: 273 ESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEM 332
Query: 361 RSYRMSMVQTEEQYIFIHQCVQLMWMKKKQQFCISDVIYENVSKS 405
RSYRMSMVQTEEQYIFIHQCVQLMWMKKKQQFCISDVIYENVSKS
Sbjct: 333 RSYRMSMVQTEEQYIFIHQCVQLMWMKKKQQFCISDVIYENVSKS 377
>gi|4506323 receptor-type protein tyrosine phosphatase O isoform b
precursor [Homo sapiens]
Length = 1188
Score = 758 bits (1956), Expect = 0.0
Identities = 377/405 (93%), Positives = 377/405 (93%), Gaps = 28/405 (6%)
Query: 1 MVTEMNPNVVVISVLAILSTLLIGLLLVTLIILRKKHLQMARECGAGTFVNFASLERDGK 60
MVTEMNPNVVVISVLAILSTLLIGLLLVTLIILRKKHLQMARECGAGTFVNFASLERDGK
Sbjct: 812 MVTEMNPNVVVISVLAILSTLLIGLLLVTLIILRKKHLQMARECGAGTFVNFASLERDGK 871
Query: 61 LPYNWRRSIFAFLTLLPSCLWTDYLLAFYINPWSKNGLKKRKLTNPVQLDDFDAYIKDMA 120
LPYNW SKNGLKKRKLTNPVQLDDFDAYIKDMA
Sbjct: 872 LPYNW----------------------------SKNGLKKRKLTNPVQLDDFDAYIKDMA 903
Query: 121 KDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGAD 180
KDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGAD
Sbjct: 904 KDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGAD 963
Query: 181 YINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYW 240
YINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYW
Sbjct: 964 YINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYW 1023
Query: 241 PFTEEPIAYGDITVEMISEEEQDDWACRHFRINYADEMQDVMHFNYTAWPDHGVPTANAA 300
PFTEEPIAYGDITVEMISEEEQDDWACRHFRINYADEMQDVMHFNYTAWPDHGVPTANAA
Sbjct: 1024 PFTEEPIAYGDITVEMISEEEQDDWACRHFRINYADEMQDVMHFNYTAWPDHGVPTANAA 1083
Query: 301 ESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEM 360
ESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEM
Sbjct: 1084 ESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEM 1143
Query: 361 RSYRMSMVQTEEQYIFIHQCVQLMWMKKKQQFCISDVIYENVSKS 405
RSYRMSMVQTEEQYIFIHQCVQLMWMKKKQQFCISDVIYENVSKS
Sbjct: 1144 RSYRMSMVQTEEQYIFIHQCVQLMWMKKKQQFCISDVIYENVSKS 1188
>gi|157952215 protein tyrosine phosphatase, receptor type, B isoform a
[Homo sapiens]
Length = 2215
Score = 297 bits (760), Expect = 1e-80
Identities = 154/329 (46%), Positives = 217/329 (65%), Gaps = 13/329 (3%)
Query: 83 DYLLAFYINPWSKNGLKKRKLTNPVQLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIP 142
D L+ ++N K RK + P++++ F+ + + DS+Y S ++EELK +G +
Sbjct: 1880 DRPLSVHLNLGQKGN---RKTSCPIKINQFEGHFMKLQADSNYLLSKEYEELKDVGRNQS 1936
Query: 143 HFAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGP 202
A LP NR KNRY NILPYD +RV+L +++++ +DYINA+YIPG N +EYI TQGP
Sbjct: 1937 CDIALLPENRGKNRYNNILPYDATRVKLSNVDDDPCSDYINASYIPGNNFRREYIVTQGP 1996
Query: 203 LPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQ 262
LP T++DFWKMV +Q IVM+TQC EK RVKCDHYWP ++ + YGD+ ++M+SE
Sbjct: 1997 LPGTKDDFWKMVWEQNVHNIVMVTQCVEKGRVKCDHYWPADQDSLYYGDLILQMLSESVL 2056
Query: 263 DDWACRHFRI---NYADEMQDVMHFNYTAWPDHGVPTANAAESILQFVHMVRQQATKS-- 317
+W R F+I D + + HF+YT WPDHGVP +S++QFV VR +S
Sbjct: 2057 PEWTIREFKICGEEQLDAHRLIRHFHYTVWPDHGVP--ETTQSLIQFVRTVRDYINRSPG 2114
Query: 318 KGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFI 377
GP ++HCSAGVGRTGTFIALDR+LQ + + VDI G V ++R +R+ MVQTE QY+++
Sbjct: 2115 AGPTVVHCSAGVGRTGTFIALDRILQQLDSKDSVDIYGAVHDLRLHRVHMVQTECQYVYL 2174
Query: 378 HQCVQLMWMKKK---QQFCISDVIYENVS 403
HQCV+ + +K +Q IYENV+
Sbjct: 2175 HQCVRDVLRARKLRSEQENPLFPIYENVN 2203
>gi|157952213 protein tyrosine phosphatase, receptor type, B isoform b
precursor [Homo sapiens]
Length = 1997
Score = 297 bits (760), Expect = 1e-80
Identities = 154/329 (46%), Positives = 217/329 (65%), Gaps = 13/329 (3%)
Query: 83 DYLLAFYINPWSKNGLKKRKLTNPVQLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIP 142
D L+ ++N K RK + P++++ F+ + + DS+Y S ++EELK +G +
Sbjct: 1662 DRPLSVHLNLGQKGN---RKTSCPIKINQFEGHFMKLQADSNYLLSKEYEELKDVGRNQS 1718
Query: 143 HFAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGP 202
A LP NR KNRY NILPYD +RV+L +++++ +DYINA+YIPG N +EYI TQGP
Sbjct: 1719 CDIALLPENRGKNRYNNILPYDATRVKLSNVDDDPCSDYINASYIPGNNFRREYIVTQGP 1778
Query: 203 LPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQ 262
LP T++DFWKMV +Q IVM+TQC EK RVKCDHYWP ++ + YGD+ ++M+SE
Sbjct: 1779 LPGTKDDFWKMVWEQNVHNIVMVTQCVEKGRVKCDHYWPADQDSLYYGDLILQMLSESVL 1838
Query: 263 DDWACRHFRI---NYADEMQDVMHFNYTAWPDHGVPTANAAESILQFVHMVRQQATKS-- 317
+W R F+I D + + HF+YT WPDHGVP +S++QFV VR +S
Sbjct: 1839 PEWTIREFKICGEEQLDAHRLIRHFHYTVWPDHGVP--ETTQSLIQFVRTVRDYINRSPG 1896
Query: 318 KGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFI 377
GP ++HCSAGVGRTGTFIALDR+LQ + + VDI G V ++R +R+ MVQTE QY+++
Sbjct: 1897 AGPTVVHCSAGVGRTGTFIALDRILQQLDSKDSVDIYGAVHDLRLHRVHMVQTECQYVYL 1956
Query: 378 HQCVQLMWMKKK---QQFCISDVIYENVS 403
HQCV+ + +K +Q IYENV+
Sbjct: 1957 HQCVRDVLRARKLRSEQENPLFPIYENVN 1985
>gi|222537743 protein tyrosine phosphatase, receptor type, Q [Homo
sapiens]
Length = 2299
Score = 283 bits (723), Expect = 3e-76
Identities = 142/308 (46%), Positives = 192/308 (62%), Gaps = 3/308 (0%)
Query: 98 LKKRKLTNPVQLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRY 157
L RK P+ F +++++ +++ KF +F EL D+ ADLP NR KNR+
Sbjct: 1974 LSYRKSIKPISKKSFLQHVEELCTNNNLKFQEEFSELPKFLQDLSSTDADLPWNRAKNRF 2033
Query: 158 TNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQ 217
NI PY+ +RV+L++ G+DYINA+YI GY P E+IATQGPLP T DFW+MV +
Sbjct: 2034 PNIKPYNNNRVKLIADASVPGSDYINASYISGYLCPNEFIATQGPLPGTVGDFWRMVWET 2093
Query: 218 KSQIIVMLTQCNEKRRVKCDHYWPFTEEPI-AYGDITVEMISEEEQDDWACRHFRINYAD 276
+++ +VMLTQC EK R++C YWP +P+ +GDI + + E+ Q DW R +I
Sbjct: 2094 RAKTLVMLTQCFEKGRIRCHQYWPEDNKPVTVFGDIVITKLMEDVQIDWTIRDLKIERHG 2153
Query: 277 EMQDVMHFNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFI 336
+ V N+TAWP+HGVP +A ++ FV +VR PMI+HCSAGVGRTG FI
Sbjct: 2154 DCMTVRQCNFTAWPEHGVPENSA--PLIHFVKLVRASRAHDTTPMIVHCSAGVGRTGVFI 2211
Query: 337 ALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWMKKKQQFCISD 396
ALD L QHI DH+FVDI GLV+E+RS RM MVQ QYIF+HQC+ + K I
Sbjct: 2212 ALDHLTQHINDHDFVDIYGLVAELRSERMCMVQNLAQYIFLHQCILDLLSNKGSNQPICF 2271
Query: 397 VIYENVSK 404
V Y + K
Sbjct: 2272 VNYSALQK 2279
>gi|148728162 protein tyrosine phosphatase, receptor type, J isoform 1
precursor [Homo sapiens]
Length = 1337
Score = 278 bits (711), Expect = 6e-75
Identities = 138/308 (44%), Positives = 208/308 (67%), Gaps = 10/308 (3%)
Query: 100 KRKLTNPVQLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTN 159
K K + +++++F+AY K DS+ F+ ++E+LKL+G+ P +AA+L NR KNRY N
Sbjct: 1014 KPKKSKLIRVENFEAYFKKQQADSNCGFAEEYEDLKLVGISQPKYAAELAENRGKNRYNN 1073
Query: 160 ILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKS 219
+LPYD SRV+L S+ DYINANY+PGY+S +++IATQGPLP T DFW+MV ++
Sbjct: 1074 VLPYDISRVKL-SVQTHSTDDYINANYMPGYHSKKDFIATQGPLPNTLKDFWRMVWEKNV 1132
Query: 220 QIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDDWACRHFRIN--YADE 277
I+MLT+C E+ R KC+ YWP +++ YGDITV M SE +W R F + E
Sbjct: 1133 YAIIMLTKCVEQGRTKCEEYWP-SKQAQDYGDITVAMTSEIVLPEWTIRDFTVKNIQTSE 1191
Query: 278 MQDVMHFNYTAWPDHGVPTANAAESILQFVHMVRQQATKS--KGPMIIHCSAGVGRTGTF 335
+ F++T+WPDHGVP + + ++ F ++VR +S + P+++HCSAGVGRTGTF
Sbjct: 1192 SHPLRQFHFTSWPDHGVP--DTTDLLINFRYLVRDYMKQSPPESPILVHCSAGVGRTGTF 1249
Query: 336 IALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWMKKKQQFCIS 395
IA+DRL+ I + VD+ G+V ++R +R MVQTE+QY+F++QCV + + + Q+
Sbjct: 1250 IAIDRLIYQIENENTVDVYGIVYDLRMHRPLMVQTEDQYVFLNQCV--LDIVRSQKDSKV 1307
Query: 396 DVIYENVS 403
D+IY+N +
Sbjct: 1308 DLIYQNTT 1315
>gi|241896926 protein tyrosine phosphatase, receptor type, H isoform
2 precursor [Homo sapiens]
Length = 937
Score = 268 bits (686), Expect = 5e-72
Identities = 137/329 (41%), Positives = 201/329 (61%), Gaps = 13/329 (3%)
Query: 85 LLAFYINPWSKNGLKKRKLTN-------PVQLDDFDAYIKDMAKDSDYKFSLQFEELKLI 137
LL F++ +K +K +L + + +DF +++ +DS+ F+ ++++L L+
Sbjct: 593 LLIFFLKRRNKKKQQKPELRDLVFSSPGDIPAEDFADHVRKNERDSNCGFADKYQQLSLV 652
Query: 138 GLDIPHFAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYI 197
G A N KNRY N+LPYD+SRV L ++EE G+DYINA+++PG SPQE+I
Sbjct: 653 GHSQSQMVASASENNAKNRYRNVLPYDWSRVPLKPIHEEPGSDYINASFMPGLWSPQEFI 712
Query: 198 ATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDITVEMI 257
ATQGPLP+T DFW++V +Q+S +VMLT C E RVKC+HYWP +P +G + V ++
Sbjct: 713 ATQGPLPQTVGDFWRLVWEQQSHTLVMLTNCMEAGRVKCEHYWPLDSQPCTHGHLRVTLV 772
Query: 258 SEEEQDDWACRHFRINYADEMQ--DVMHFNYTAWPDHGVPTANAAESILQFVHMVRQ--Q 313
EE ++W R + +E + V F+Y AWPDHGVP ++ +++L F M+RQ
Sbjct: 773 GEEVMENWTVRELLLLQVEEQKTLSVRQFHYQAWPDHGVP--SSPDTLLAFWRMLRQWLD 830
Query: 314 ATKSKGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQ 373
T GP I+HCSAGVGRTGT IALD LL+ ++ + V +MR R MVQTE Q
Sbjct: 831 QTMEGGPPIVHCSAGVGRTGTLIALDVLLRQLQSEGLLGPFSFVRKMRESRPLMVQTEAQ 890
Query: 374 YIFIHQCVQLMWMKKKQQFCISDVIYENV 402
Y+F+HQC+ + Q +V YE+V
Sbjct: 891 YVFLHQCILRFLQQSAQAPAEKEVPYEDV 919
>gi|241896924 protein tyrosine phosphatase, receptor type, H isoform 1
precursor [Homo sapiens]
Length = 1115
Score = 268 bits (686), Expect = 5e-72
Identities = 137/329 (41%), Positives = 201/329 (61%), Gaps = 13/329 (3%)
Query: 85 LLAFYINPWSKNGLKKRKLTN-------PVQLDDFDAYIKDMAKDSDYKFSLQFEELKLI 137
LL F++ +K +K +L + + +DF +++ +DS+ F+ ++++L L+
Sbjct: 771 LLIFFLKRRNKKKQQKPELRDLVFSSPGDIPAEDFADHVRKNERDSNCGFADKYQQLSLV 830
Query: 138 GLDIPHFAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYI 197
G A N KNRY N+LPYD+SRV L ++EE G+DYINA+++PG SPQE+I
Sbjct: 831 GHSQSQMVASASENNAKNRYRNVLPYDWSRVPLKPIHEEPGSDYINASFMPGLWSPQEFI 890
Query: 198 ATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDITVEMI 257
ATQGPLP+T DFW++V +Q+S +VMLT C E RVKC+HYWP +P +G + V ++
Sbjct: 891 ATQGPLPQTVGDFWRLVWEQQSHTLVMLTNCMEAGRVKCEHYWPLDSQPCTHGHLRVTLV 950
Query: 258 SEEEQDDWACRHFRINYADEMQ--DVMHFNYTAWPDHGVPTANAAESILQFVHMVRQ--Q 313
EE ++W R + +E + V F+Y AWPDHGVP ++ +++L F M+RQ
Sbjct: 951 GEEVMENWTVRELLLLQVEEQKTLSVRQFHYQAWPDHGVP--SSPDTLLAFWRMLRQWLD 1008
Query: 314 ATKSKGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQ 373
T GP I+HCSAGVGRTGT IALD LL+ ++ + V +MR R MVQTE Q
Sbjct: 1009 QTMEGGPPIVHCSAGVGRTGTLIALDVLLRQLQSEGLLGPFSFVRKMRESRPLMVQTEAQ 1068
Query: 374 YIFIHQCVQLMWMKKKQQFCISDVIYENV 402
Y+F+HQC+ + Q +V YE+V
Sbjct: 1069 YVFLHQCILRFLQQSAQAPAEKEVPYEDV 1097
>gi|109633041 protein tyrosine phosphatase, receptor type, F isoform 1
precursor [Homo sapiens]
Length = 1907
Score = 225 bits (574), Expect = 5e-59
Identities = 119/278 (42%), Positives = 168/278 (60%), Gaps = 6/278 (2%)
Query: 106 PVQLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDF 165
P+ + D I+ + + KFS ++E + G ++L +N+ KNRY N++ YD
Sbjct: 1331 PIPITDLADNIERLKANDGLKFSQEYESIDP-GQQFTWENSNLEVNKPKNRYANVIAYDH 1389
Query: 166 SRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVML 225
SRV L S++ G+DYINANYI GY YIATQGPLPET DFW+MV +Q++ +VM+
Sbjct: 1390 SRVILTSIDGVPGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRTATVVMM 1449
Query: 226 TQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDDWACRHFRINY--ADEMQDVMH 283
T+ EK RVKCD YWP G I V ++ E + R F ++ + E +++
Sbjct: 1450 TRLEEKSRVKCDQYWP-ARGTETCGLIQVTLLDTVELATYTVRTFALHKSGSSEKRELRQ 1508
Query: 284 FNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQ 343
F + AWPDHGVP IL F+ V+ GPM++HCSAGVGRTG FI +D +L+
Sbjct: 1509 FQFMAWPDHGVP--EYPTPILAFLRRVKACNPLDAGPMVVHCSAGVGRTGCFIVIDAMLE 1566
Query: 344 HIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCV 381
++ + VDI G V+ MRS R MVQTE+QY+FIH+ +
Sbjct: 1567 RMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEAL 1604
Score = 188 bits (477), Expect = 9e-48
Identities = 103/251 (41%), Positives = 145/251 (57%), Gaps = 13/251 (5%)
Query: 133 ELKLIGLDIPH----FAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIP 188
E KL+ H +A+LP N+ KNR NI+PY+ +RV L + EG+DYINA+++
Sbjct: 1642 EFKLLASSKAHTSRFISANLPCNKFKNRLVNIMPYELTRVCLQPIRGVEGSDYINASFLD 1701
Query: 189 GYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIA 248
GY + YIATQGPL E+ DFW+M+ + S IIVMLT+ E R KC YWP E
Sbjct: 1702 GYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWP-AERSAR 1760
Query: 249 YGDITVEMISEEEQDDWACRHFRINYADEMQD--VMHFNYTAWPDHGVPTANAAESILQF 306
Y V+ ++E + R F++ A + Q + F +T WP+ GVP E + F
Sbjct: 1761 YQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVP--KTGEGFIDF 1818
Query: 307 ---VHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSY 363
VH ++Q + GP+ +HCSAGVGRTG FI L +L+ +R VD+ V +R+
Sbjct: 1819 IGQVHKTKEQFGQD-GPITVHCSAGVGRTGVFITLSIVLERMRYEGVVDMFQTVKTLRTQ 1877
Query: 364 RMSMVQTEEQY 374
R +MVQTE+QY
Sbjct: 1878 RPAMVQTEDQY 1888
>gi|109633039 protein tyrosine phosphatase, receptor type, F isoform 2
precursor [Homo sapiens]
Length = 1898
Score = 225 bits (574), Expect = 5e-59
Identities = 119/278 (42%), Positives = 168/278 (60%), Gaps = 6/278 (2%)
Query: 106 PVQLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDF 165
P+ + D I+ + + KFS ++E + G ++L +N+ KNRY N++ YD
Sbjct: 1322 PIPITDLADNIERLKANDGLKFSQEYESIDP-GQQFTWENSNLEVNKPKNRYANVIAYDH 1380
Query: 166 SRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVML 225
SRV L S++ G+DYINANYI GY YIATQGPLPET DFW+MV +Q++ +VM+
Sbjct: 1381 SRVILTSIDGVPGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRTATVVMM 1440
Query: 226 TQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDDWACRHFRINY--ADEMQDVMH 283
T+ EK RVKCD YWP G I V ++ E + R F ++ + E +++
Sbjct: 1441 TRLEEKSRVKCDQYWP-ARGTETCGLIQVTLLDTVELATYTVRTFALHKSGSSEKRELRQ 1499
Query: 284 FNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQ 343
F + AWPDHGVP IL F+ V+ GPM++HCSAGVGRTG FI +D +L+
Sbjct: 1500 FQFMAWPDHGVP--EYPTPILAFLRRVKACNPLDAGPMVVHCSAGVGRTGCFIVIDAMLE 1557
Query: 344 HIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCV 381
++ + VDI G V+ MRS R MVQTE+QY+FIH+ +
Sbjct: 1558 RMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEAL 1595
Score = 188 bits (477), Expect = 9e-48
Identities = 103/251 (41%), Positives = 145/251 (57%), Gaps = 13/251 (5%)
Query: 133 ELKLIGLDIPH----FAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIP 188
E KL+ H +A+LP N+ KNR NI+PY+ +RV L + EG+DYINA+++
Sbjct: 1633 EFKLLASSKAHTSRFISANLPCNKFKNRLVNIMPYELTRVCLQPIRGVEGSDYINASFLD 1692
Query: 189 GYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIA 248
GY + YIATQGPL E+ DFW+M+ + S IIVMLT+ E R KC YWP E
Sbjct: 1693 GYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWP-AERSAR 1751
Query: 249 YGDITVEMISEEEQDDWACRHFRINYADEMQD--VMHFNYTAWPDHGVPTANAAESILQF 306
Y V+ ++E + R F++ A + Q + F +T WP+ GVP E + F
Sbjct: 1752 YQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVP--KTGEGFIDF 1809
Query: 307 ---VHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSY 363
VH ++Q + GP+ +HCSAGVGRTG FI L +L+ +R VD+ V +R+
Sbjct: 1810 IGQVHKTKEQFGQD-GPITVHCSAGVGRTGVFITLSIVLERMRYEGVVDMFQTVKTLRTQ 1868
Query: 364 RMSMVQTEEQY 374
R +MVQTE+QY
Sbjct: 1869 RPAMVQTEDQY 1879
>gi|104487611 protein tyrosine phosphatase, receptor type, sigma
isoform 4 precursor [Homo sapiens]
Length = 1505
Score = 223 bits (569), Expect = 2e-58
Identities = 118/278 (42%), Positives = 165/278 (59%), Gaps = 6/278 (2%)
Query: 106 PVQLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDF 165
P+ + D + + + + K S ++E + G ++L +N+ KNRY N++ YD
Sbjct: 929 PIPIADMAEHTERLKANDSLKLSQEYESIDP-GQQFTWEHSNLEVNKPKNRYANVIAYDH 987
Query: 166 SRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVML 225
SRV L + G+DYINANY+ GY YIATQGPLPET DFW+MV +Q+S IVM+
Sbjct: 988 SRVILQPIEGIMGSDYINANYVDGYRCQNAYIATQGPLPETFGDFWRMVWEQRSATIVMM 1047
Query: 226 TQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDDWACRHFRI--NYADEMQDVMH 283
T+ EK R+KCD YWP YG I V ++ E + R F + N + E ++V
Sbjct: 1048 TRLEEKSRIKCDQYWP-NRGTETYGFIQVTLLDTIELATFCVRTFSLHKNGSSEKREVRQ 1106
Query: 284 FNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQ 343
F +TAWPDHGVP L F+ V+ GP+++HCSAGVGRTG FI +D +L+
Sbjct: 1107 FQFTAWPDHGVP--EYPTPFLAFLRRVKTCNPPDAGPIVVHCSAGVGRTGCFIVIDAMLE 1164
Query: 344 HIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCV 381
I+ + VD+ G V+ MRS R MVQTE+QY FIH+ +
Sbjct: 1165 RIKPEKTVDVYGHVTLMRSQRNYMVQTEDQYSFIHEAL 1202
Score = 191 bits (486), Expect = 8e-49
Identities = 103/240 (42%), Positives = 144/240 (60%), Gaps = 9/240 (3%)
Query: 145 AADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLP 204
+A+LP N+ KNR NI+PY+ +RV L + EG+DYINA++I GY + YIATQGPL
Sbjct: 1256 SANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLA 1315
Query: 205 ETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDD 264
ET DFW+M+ + S I+VMLT+ E R KC YWP E Y V+ ++E
Sbjct: 1316 ETTEDFWRMLWENNSTIVVMLTKLREMGREKCHQYWP-AERSARYQYFVVDPMAEYNMPQ 1374
Query: 265 WACRHFRINYADEMQD--VMHFNYTAWPDHGVPTANAAESILQF---VHMVRQQATKSKG 319
+ R F++ A + Q V F +T WP+ GVP + E + F VH ++Q + G
Sbjct: 1375 YILREFKVTDARDGQSRTVRQFQFTDWPEQGVP--KSGEGFIDFIGQVHKTKEQFGQD-G 1431
Query: 320 PMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQ 379
P+ +HCSAGVGRTG FI L +L+ +R VDI V +R+ R +MVQTE++Y F +Q
Sbjct: 1432 PISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDEYQFCYQ 1491
>gi|104487297 protein tyrosine phosphatase, receptor type, sigma
isoform 2 precursor [Homo sapiens]
Length = 1910
Score = 223 bits (569), Expect = 2e-58
Identities = 118/278 (42%), Positives = 165/278 (59%), Gaps = 6/278 (2%)
Query: 106 PVQLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDF 165
P+ + D + + + + K S ++E + G ++L +N+ KNRY N++ YD
Sbjct: 1334 PIPIADMAEHTERLKANDSLKLSQEYESIDP-GQQFTWEHSNLEVNKPKNRYANVIAYDH 1392
Query: 166 SRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVML 225
SRV L + G+DYINANY+ GY YIATQGPLPET DFW+MV +Q+S IVM+
Sbjct: 1393 SRVILQPIEGIMGSDYINANYVDGYRCQNAYIATQGPLPETFGDFWRMVWEQRSATIVMM 1452
Query: 226 TQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDDWACRHFRI--NYADEMQDVMH 283
T+ EK R+KCD YWP YG I V ++ E + R F + N + E ++V
Sbjct: 1453 TRLEEKSRIKCDQYWP-NRGTETYGFIQVTLLDTIELATFCVRTFSLHKNGSSEKREVRQ 1511
Query: 284 FNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQ 343
F +TAWPDHGVP L F+ V+ GP+++HCSAGVGRTG FI +D +L+
Sbjct: 1512 FQFTAWPDHGVP--EYPTPFLAFLRRVKTCNPPDAGPIVVHCSAGVGRTGCFIVIDAMLE 1569
Query: 344 HIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCV 381
I+ + VD+ G V+ MRS R MVQTE+QY FIH+ +
Sbjct: 1570 RIKPEKTVDVYGHVTLMRSQRNYMVQTEDQYSFIHEAL 1607
Score = 191 bits (486), Expect = 8e-49
Identities = 103/240 (42%), Positives = 144/240 (60%), Gaps = 9/240 (3%)
Query: 145 AADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLP 204
+A+LP N+ KNR NI+PY+ +RV L + EG+DYINA++I GY + YIATQGPL
Sbjct: 1661 SANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLA 1720
Query: 205 ETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDD 264
ET DFW+M+ + S I+VMLT+ E R KC YWP E Y V+ ++E
Sbjct: 1721 ETTEDFWRMLWENNSTIVVMLTKLREMGREKCHQYWP-AERSARYQYFVVDPMAEYNMPQ 1779
Query: 265 WACRHFRINYADEMQD--VMHFNYTAWPDHGVPTANAAESILQF---VHMVRQQATKSKG 319
+ R F++ A + Q V F +T WP+ GVP + E + F VH ++Q + G
Sbjct: 1780 YILREFKVTDARDGQSRTVRQFQFTDWPEQGVP--KSGEGFIDFIGQVHKTKEQFGQD-G 1836
Query: 320 PMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQ 379
P+ +HCSAGVGRTG FI L +L+ +R VDI V +R+ R +MVQTE++Y F +Q
Sbjct: 1837 PISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDEYQFCYQ 1896
>gi|104487295 protein tyrosine phosphatase, receptor type, sigma
isoform 3 precursor [Homo sapiens]
Length = 1501
Score = 223 bits (569), Expect = 2e-58
Identities = 118/278 (42%), Positives = 165/278 (59%), Gaps = 6/278 (2%)
Query: 106 PVQLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDF 165
P+ + D + + + + K S ++E + G ++L +N+ KNRY N++ YD
Sbjct: 925 PIPIADMAEHTERLKANDSLKLSQEYESIDP-GQQFTWEHSNLEVNKPKNRYANVIAYDH 983
Query: 166 SRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVML 225
SRV L + G+DYINANY+ GY YIATQGPLPET DFW+MV +Q+S IVM+
Sbjct: 984 SRVILQPIEGIMGSDYINANYVDGYRCQNAYIATQGPLPETFGDFWRMVWEQRSATIVMM 1043
Query: 226 TQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDDWACRHFRI--NYADEMQDVMH 283
T+ EK R+KCD YWP YG I V ++ E + R F + N + E ++V
Sbjct: 1044 TRLEEKSRIKCDQYWP-NRGTETYGFIQVTLLDTIELATFCVRTFSLHKNGSSEKREVRQ 1102
Query: 284 FNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQ 343
F +TAWPDHGVP L F+ V+ GP+++HCSAGVGRTG FI +D +L+
Sbjct: 1103 FQFTAWPDHGVP--EYPTPFLAFLRRVKTCNPPDAGPIVVHCSAGVGRTGCFIVIDAMLE 1160
Query: 344 HIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCV 381
I+ + VD+ G V+ MRS R MVQTE+QY FIH+ +
Sbjct: 1161 RIKPEKTVDVYGHVTLMRSQRNYMVQTEDQYSFIHEAL 1198
Score = 191 bits (486), Expect = 8e-49
Identities = 103/240 (42%), Positives = 144/240 (60%), Gaps = 9/240 (3%)
Query: 145 AADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLP 204
+A+LP N+ KNR NI+PY+ +RV L + EG+DYINA++I GY + YIATQGPL
Sbjct: 1252 SANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLA 1311
Query: 205 ETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDD 264
ET DFW+M+ + S I+VMLT+ E R KC YWP E Y V+ ++E
Sbjct: 1312 ETTEDFWRMLWENNSTIVVMLTKLREMGREKCHQYWP-AERSARYQYFVVDPMAEYNMPQ 1370
Query: 265 WACRHFRINYADEMQD--VMHFNYTAWPDHGVPTANAAESILQF---VHMVRQQATKSKG 319
+ R F++ A + Q V F +T WP+ GVP + E + F VH ++Q + G
Sbjct: 1371 YILREFKVTDARDGQSRTVRQFQFTDWPEQGVP--KSGEGFIDFIGQVHKTKEQFGQD-G 1427
Query: 320 PMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQ 379
P+ +HCSAGVGRTG FI L +L+ +R VDI V +R+ R +MVQTE++Y F +Q
Sbjct: 1428 PISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDEYQFCYQ 1487
>gi|104487006 protein tyrosine phosphatase, receptor type, sigma
isoform 1 precursor [Homo sapiens]
Length = 1948
Score = 223 bits (569), Expect = 2e-58
Identities = 118/278 (42%), Positives = 165/278 (59%), Gaps = 6/278 (2%)
Query: 106 PVQLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDF 165
P+ + D + + + + K S ++E + G ++L +N+ KNRY N++ YD
Sbjct: 1372 PIPIADMAEHTERLKANDSLKLSQEYESIDP-GQQFTWEHSNLEVNKPKNRYANVIAYDH 1430
Query: 166 SRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVML 225
SRV L + G+DYINANY+ GY YIATQGPLPET DFW+MV +Q+S IVM+
Sbjct: 1431 SRVILQPIEGIMGSDYINANYVDGYRCQNAYIATQGPLPETFGDFWRMVWEQRSATIVMM 1490
Query: 226 TQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDDWACRHFRI--NYADEMQDVMH 283
T+ EK R+KCD YWP YG I V ++ E + R F + N + E ++V
Sbjct: 1491 TRLEEKSRIKCDQYWP-NRGTETYGFIQVTLLDTIELATFCVRTFSLHKNGSSEKREVRQ 1549
Query: 284 FNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQ 343
F +TAWPDHGVP L F+ V+ GP+++HCSAGVGRTG FI +D +L+
Sbjct: 1550 FQFTAWPDHGVP--EYPTPFLAFLRRVKTCNPPDAGPIVVHCSAGVGRTGCFIVIDAMLE 1607
Query: 344 HIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCV 381
I+ + VD+ G V+ MRS R MVQTE+QY FIH+ +
Sbjct: 1608 RIKPEKTVDVYGHVTLMRSQRNYMVQTEDQYSFIHEAL 1645
Score = 191 bits (486), Expect = 8e-49
Identities = 103/240 (42%), Positives = 144/240 (60%), Gaps = 9/240 (3%)
Query: 145 AADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLP 204
+A+LP N+ KNR NI+PY+ +RV L + EG+DYINA++I GY + YIATQGPL
Sbjct: 1699 SANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLA 1758
Query: 205 ETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDD 264
ET DFW+M+ + S I+VMLT+ E R KC YWP E Y V+ ++E
Sbjct: 1759 ETTEDFWRMLWENNSTIVVMLTKLREMGREKCHQYWP-AERSARYQYFVVDPMAEYNMPQ 1817
Query: 265 WACRHFRINYADEMQD--VMHFNYTAWPDHGVPTANAAESILQF---VHMVRQQATKSKG 319
+ R F++ A + Q V F +T WP+ GVP + E + F VH ++Q + G
Sbjct: 1818 YILREFKVTDARDGQSRTVRQFQFTDWPEQGVP--KSGEGFIDFIGQVHKTKEQFGQD-G 1874
Query: 320 PMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQ 379
P+ +HCSAGVGRTG FI L +L+ +R VDI V +R+ R +MVQTE++Y F +Q
Sbjct: 1875 PISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDEYQFCYQ 1934
>gi|104487002 protein tyrosine phosphatase, receptor type, D isoform 5
precursor [Homo sapiens]
Length = 1502
Score = 223 bits (569), Expect = 2e-58
Identities = 116/278 (41%), Positives = 169/278 (60%), Gaps = 6/278 (2%)
Query: 106 PVQLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDF 165
P+ + + +I+ + + + KFS ++E + G ++L +N+ KNRY N++ YD
Sbjct: 926 PIPILELADHIERLKANDNLKFSQEYESIDP-GQQFTWEHSNLEVNKPKNRYANVIAYDH 984
Query: 166 SRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVML 225
SRV L ++ G+DY+NANYI GY YIATQG LPET DFW+M+ +Q+S +VM+
Sbjct: 985 SRVLLSAIEGIPGSDYVNANYIDGYRKQNAYIATQGSLPETFGDFWRMIWEQRSATVVMM 1044
Query: 226 TQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDDWACRHFRI--NYADEMQDVMH 283
T+ E+ RVKCD YWP + +G + V ++ E + R F + N + E ++V
Sbjct: 1045 TKLEERSRVKCDQYWP-SRGTETHGLVQVTLLDTVELATYCVRTFALYKNGSSEKREVRQ 1103
Query: 284 FNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQ 343
F +TAWPDHGVP L F+ V+ GPM++HCSAGVGRTG FI +D +L+
Sbjct: 1104 FQFTAWPDHGVP--EHPTPFLAFLRRVKTCNPPDAGPMVVHCSAGVGRTGCFIVIDAMLE 1161
Query: 344 HIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCV 381
I+ + VDI G V+ MR+ R MVQTE+QYIFIH +
Sbjct: 1162 RIKHEKTVDIYGHVTLMRAQRNYMVQTEDQYIFIHDAL 1199
Score = 191 bits (484), Expect = 1e-48
Identities = 103/240 (42%), Positives = 144/240 (60%), Gaps = 9/240 (3%)
Query: 145 AADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLP 204
+A+LP N+ KNR NI+PY+ +RV L + EG+DYINA++I GY + YIATQGPL
Sbjct: 1253 SANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLA 1312
Query: 205 ETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDD 264
ET DFW+M+ + S I+VMLT+ E R KC YWP E Y V+ ++E
Sbjct: 1313 ETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWP-AERSARYQYFVVDPMAEYNMPQ 1371
Query: 265 WACRHFRINYADEMQD--VMHFNYTAWPDHGVPTANAAESILQF---VHMVRQQATKSKG 319
+ R F++ A + Q V F +T WP+ GVP + E + F VH ++Q + G
Sbjct: 1372 YILREFKVTDARDGQSRTVRQFQFTDWPEQGVP--KSGEGFIDFIGQVHKTKEQFGQD-G 1428
Query: 320 PMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQ 379
P+ +HCSAGVGRTG FI L +L+ +R VDI V +R+ R +MVQTE+QY F ++
Sbjct: 1429 PISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDQYQFSYR 1488
>gi|4506309 protein tyrosine phosphatase, receptor type, D isoform 1
precursor [Homo sapiens]
Length = 1912
Score = 223 bits (569), Expect = 2e-58
Identities = 116/278 (41%), Positives = 169/278 (60%), Gaps = 6/278 (2%)
Query: 106 PVQLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDF 165
P+ + + +I+ + + + KFS ++E + G ++L +N+ KNRY N++ YD
Sbjct: 1336 PIPILELADHIERLKANDNLKFSQEYESIDP-GQQFTWEHSNLEVNKPKNRYANVIAYDH 1394
Query: 166 SRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVML 225
SRV L ++ G+DY+NANYI GY YIATQG LPET DFW+M+ +Q+S +VM+
Sbjct: 1395 SRVLLSAIEGIPGSDYVNANYIDGYRKQNAYIATQGSLPETFGDFWRMIWEQRSATVVMM 1454
Query: 226 TQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDDWACRHFRI--NYADEMQDVMH 283
T+ E+ RVKCD YWP + +G + V ++ E + R F + N + E ++V
Sbjct: 1455 TKLEERSRVKCDQYWP-SRGTETHGLVQVTLLDTVELATYCVRTFALYKNGSSEKREVRQ 1513
Query: 284 FNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQ 343
F +TAWPDHGVP L F+ V+ GPM++HCSAGVGRTG FI +D +L+
Sbjct: 1514 FQFTAWPDHGVP--EHPTPFLAFLRRVKTCNPPDAGPMVVHCSAGVGRTGCFIVIDAMLE 1571
Query: 344 HIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCV 381
I+ + VDI G V+ MR+ R MVQTE+QYIFIH +
Sbjct: 1572 RIKHEKTVDIYGHVTLMRAQRNYMVQTEDQYIFIHDAL 1609
Score = 191 bits (484), Expect = 1e-48
Identities = 103/240 (42%), Positives = 144/240 (60%), Gaps = 9/240 (3%)
Query: 145 AADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLP 204
+A+LP N+ KNR NI+PY+ +RV L + EG+DYINA++I GY + YIATQGPL
Sbjct: 1663 SANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLA 1722
Query: 205 ETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDD 264
ET DFW+M+ + S I+VMLT+ E R KC YWP E Y V+ ++E
Sbjct: 1723 ETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWP-AERSARYQYFVVDPMAEYNMPQ 1781
Query: 265 WACRHFRINYADEMQD--VMHFNYTAWPDHGVPTANAAESILQF---VHMVRQQATKSKG 319
+ R F++ A + Q V F +T WP+ GVP + E + F VH ++Q + G
Sbjct: 1782 YILREFKVTDARDGQSRTVRQFQFTDWPEQGVP--KSGEGFIDFIGQVHKTKEQFGQD-G 1838
Query: 320 PMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQ 379
P+ +HCSAGVGRTG FI L +L+ +R VDI V +R+ R +MVQTE+QY F ++
Sbjct: 1839 PISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDQYQFSYR 1898
>gi|18860890 protein tyrosine phosphatase, receptor type, D isoform 2
precursor [Homo sapiens]
Length = 1899
Score = 223 bits (569), Expect = 2e-58
Identities = 116/278 (41%), Positives = 169/278 (60%), Gaps = 6/278 (2%)
Query: 106 PVQLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDF 165
P+ + + +I+ + + + KFS ++E + G ++L +N+ KNRY N++ YD
Sbjct: 1323 PIPILELADHIERLKANDNLKFSQEYESIDP-GQQFTWEHSNLEVNKPKNRYANVIAYDH 1381
Query: 166 SRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVML 225
SRV L ++ G+DY+NANYI GY YIATQG LPET DFW+M+ +Q+S +VM+
Sbjct: 1382 SRVLLSAIEGIPGSDYVNANYIDGYRKQNAYIATQGSLPETFGDFWRMIWEQRSATVVMM 1441
Query: 226 TQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDDWACRHFRI--NYADEMQDVMH 283
T+ E+ RVKCD YWP + +G + V ++ E + R F + N + E ++V
Sbjct: 1442 TKLEERSRVKCDQYWP-SRGTETHGLVQVTLLDTVELATYCVRTFALYKNGSSEKREVRQ 1500
Query: 284 FNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQ 343
F +TAWPDHGVP L F+ V+ GPM++HCSAGVGRTG FI +D +L+
Sbjct: 1501 FQFTAWPDHGVP--EHPTPFLAFLRRVKTCNPPDAGPMVVHCSAGVGRTGCFIVIDAMLE 1558
Query: 344 HIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCV 381
I+ + VDI G V+ MR+ R MVQTE+QYIFIH +
Sbjct: 1559 RIKHEKTVDIYGHVTLMRAQRNYMVQTEDQYIFIHDAL 1596
Score = 191 bits (484), Expect = 1e-48
Identities = 103/240 (42%), Positives = 144/240 (60%), Gaps = 9/240 (3%)
Query: 145 AADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLP 204
+A+LP N+ KNR NI+PY+ +RV L + EG+DYINA++I GY + YIATQGPL
Sbjct: 1650 SANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLA 1709
Query: 205 ETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDD 264
ET DFW+M+ + S I+VMLT+ E R KC YWP E Y V+ ++E
Sbjct: 1710 ETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWP-AERSARYQYFVVDPMAEYNMPQ 1768
Query: 265 WACRHFRINYADEMQD--VMHFNYTAWPDHGVPTANAAESILQF---VHMVRQQATKSKG 319
+ R F++ A + Q V F +T WP+ GVP + E + F VH ++Q + G
Sbjct: 1769 YILREFKVTDARDGQSRTVRQFQFTDWPEQGVP--KSGEGFIDFIGQVHKTKEQFGQD-G 1825
Query: 320 PMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQ 379
P+ +HCSAGVGRTG FI L +L+ +R VDI V +R+ R +MVQTE+QY F ++
Sbjct: 1826 PISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDQYQFSYR 1885
>gi|18860892 protein tyrosine phosphatase, receptor type, D isoform 3
precursor [Homo sapiens]
Length = 1903
Score = 223 bits (569), Expect = 2e-58
Identities = 116/278 (41%), Positives = 169/278 (60%), Gaps = 6/278 (2%)
Query: 106 PVQLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDF 165
P+ + + +I+ + + + KFS ++E + G ++L +N+ KNRY N++ YD
Sbjct: 1327 PIPILELADHIERLKANDNLKFSQEYESIDP-GQQFTWEHSNLEVNKPKNRYANVIAYDH 1385
Query: 166 SRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVML 225
SRV L ++ G+DY+NANYI GY YIATQG LPET DFW+M+ +Q+S +VM+
Sbjct: 1386 SRVLLSAIEGIPGSDYVNANYIDGYRKQNAYIATQGSLPETFGDFWRMIWEQRSATVVMM 1445
Query: 226 TQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDDWACRHFRI--NYADEMQDVMH 283
T+ E+ RVKCD YWP + +G + V ++ E + R F + N + E ++V
Sbjct: 1446 TKLEERSRVKCDQYWP-SRGTETHGLVQVTLLDTVELATYCVRTFALYKNGSSEKREVRQ 1504
Query: 284 FNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQ 343
F +TAWPDHGVP L F+ V+ GPM++HCSAGVGRTG FI +D +L+
Sbjct: 1505 FQFTAWPDHGVP--EHPTPFLAFLRRVKTCNPPDAGPMVVHCSAGVGRTGCFIVIDAMLE 1562
Query: 344 HIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCV 381
I+ + VDI G V+ MR+ R MVQTE+QYIFIH +
Sbjct: 1563 RIKHEKTVDIYGHVTLMRAQRNYMVQTEDQYIFIHDAL 1600
Score = 191 bits (484), Expect = 1e-48
Identities = 103/240 (42%), Positives = 144/240 (60%), Gaps = 9/240 (3%)
Query: 145 AADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLP 204
+A+LP N+ KNR NI+PY+ +RV L + EG+DYINA++I GY + YIATQGPL
Sbjct: 1654 SANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLA 1713
Query: 205 ETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDD 264
ET DFW+M+ + S I+VMLT+ E R KC YWP E Y V+ ++E
Sbjct: 1714 ETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWP-AERSARYQYFVVDPMAEYNMPQ 1772
Query: 265 WACRHFRINYADEMQD--VMHFNYTAWPDHGVPTANAAESILQF---VHMVRQQATKSKG 319
+ R F++ A + Q V F +T WP+ GVP + E + F VH ++Q + G
Sbjct: 1773 YILREFKVTDARDGQSRTVRQFQFTDWPEQGVP--KSGEGFIDFIGQVHKTKEQFGQD-G 1829
Query: 320 PMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQ 379
P+ +HCSAGVGRTG FI L +L+ +R VDI V +R+ R +MVQTE+QY F ++
Sbjct: 1830 PISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDQYQFSYR 1889
>gi|18860894 protein tyrosine phosphatase, receptor type, D isoform 4
precursor [Homo sapiens]
Length = 1501
Score = 223 bits (569), Expect = 2e-58
Identities = 116/278 (41%), Positives = 169/278 (60%), Gaps = 6/278 (2%)
Query: 106 PVQLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDF 165
P+ + + +I+ + + + KFS ++E + G ++L +N+ KNRY N++ YD
Sbjct: 925 PIPILELADHIERLKANDNLKFSQEYESIDP-GQQFTWEHSNLEVNKPKNRYANVIAYDH 983
Query: 166 SRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVML 225
SRV L ++ G+DY+NANYI GY YIATQG LPET DFW+M+ +Q+S +VM+
Sbjct: 984 SRVLLSAIEGIPGSDYVNANYIDGYRKQNAYIATQGSLPETFGDFWRMIWEQRSATVVMM 1043
Query: 226 TQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDDWACRHFRI--NYADEMQDVMH 283
T+ E+ RVKCD YWP + +G + V ++ E + R F + N + E ++V
Sbjct: 1044 TKLEERSRVKCDQYWP-SRGTETHGLVQVTLLDTVELATYCVRTFALYKNGSSEKREVRQ 1102
Query: 284 FNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQ 343
F +TAWPDHGVP L F+ V+ GPM++HCSAGVGRTG FI +D +L+
Sbjct: 1103 FQFTAWPDHGVP--EHPTPFLAFLRRVKTCNPPDAGPMVVHCSAGVGRTGCFIVIDAMLE 1160
Query: 344 HIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCV 381
I+ + VDI G V+ MR+ R MVQTE+QYIFIH +
Sbjct: 1161 RIKHEKTVDIYGHVTLMRAQRNYMVQTEDQYIFIHDAL 1198
Score = 191 bits (484), Expect = 1e-48
Identities = 103/240 (42%), Positives = 144/240 (60%), Gaps = 9/240 (3%)
Query: 145 AADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLP 204
+A+LP N+ KNR NI+PY+ +RV L + EG+DYINA++I GY + YIATQGPL
Sbjct: 1252 SANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLA 1311
Query: 205 ETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDD 264
ET DFW+M+ + S I+VMLT+ E R KC YWP E Y V+ ++E
Sbjct: 1312 ETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWP-AERSARYQYFVVDPMAEYNMPQ 1370
Query: 265 WACRHFRINYADEMQD--VMHFNYTAWPDHGVPTANAAESILQF---VHMVRQQATKSKG 319
+ R F++ A + Q V F +T WP+ GVP + E + F VH ++Q + G
Sbjct: 1371 YILREFKVTDARDGQSRTVRQFQFTDWPEQGVP--KSGEGFIDFIGQVHKTKEQFGQD-G 1427
Query: 320 PMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQ 379
P+ +HCSAGVGRTG FI L +L+ +R VDI V +R+ R +MVQTE+QY F ++
Sbjct: 1428 PISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDQYQFSYR 1487
>gi|148539860 protein tyrosine phosphatase, receptor type, T isoform 2
precursor [Homo sapiens]
Length = 1441
Score = 222 bits (566), Expect = 4e-58
Identities = 118/277 (42%), Positives = 167/277 (60%), Gaps = 7/277 (2%)
Query: 107 VQLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDFS 166
+++ D +I M + Y F ++E L G A NR KNRY NI+ YD S
Sbjct: 869 IRVADLLQHITQMKRGQGYGFKEEYEALPE-GQTASWDTAKEDENRNKNRYGNIISYDHS 927
Query: 167 RVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLT 226
RVRL+ ++ + +DYINANYI GY+ P+ YIATQGP+ ET DFW+M+ Q+ S IVM+T
Sbjct: 928 RVRLLVLDGDPHSDYINANYIDGYHRPRHYIATQGPMQETVKDFWRMIWQENSASIVMVT 987
Query: 227 QCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDDWACRHFRINYA--DEMQDVMHF 284
E RVKC YWP ++ YGDI V +I E ++ R F + E++++ F
Sbjct: 988 NLVEVGRVKCVRYWP--DDTEVYGDIKVTLIETEPLAEYVIRTFTVQKKGYHEIRELRLF 1045
Query: 285 NYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQH 344
++T+WPDHGVP A +L FV V+ GP+++HCSAG GRTG FIA+D +L
Sbjct: 1046 HFTSWPDHGVPC--YATGLLGFVRQVKFLNPPEAGPIVVHCSAGAGRTGCFIAIDTMLDM 1103
Query: 345 IRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCV 381
+ VDI V E+R+ R+++VQTEEQY+F+H +
Sbjct: 1104 AENEGVVDIFNCVRELRAQRVNLVQTEEQYVFVHDAI 1140
Score = 128 bits (321), Expect = 1e-29
Identities = 78/239 (32%), Positives = 125/239 (52%), Gaps = 12/239 (5%)
Query: 148 LPLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETR 207
LP N KNR ++LP D L+S+ + E ++YINA + + P ++ TQ PLP T
Sbjct: 1199 LPRNHDKNRSMDVLPLDRCLPFLISV-DGESSNYINAALMDSHKQPAAFVVTQHPLPNTV 1257
Query: 208 NDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDDWAC 267
DFW++V +VML + + + C YWP + YG I VE +S + +D
Sbjct: 1258 ADFWRLVFDYNCSSVVMLNEMDTAQF--CMQYWP-EKTSGCYGPIQVEFVSADIDEDIIH 1314
Query: 268 RHFRINYADEMQD----VMHFNYTAWPDHGVPTANAAESILQFVHMV---RQQATKSKGP 320
R FRI QD V H Y WP + T + S+L+ V + ++Q +G
Sbjct: 1315 RIFRICNMARPQDGYRIVQHLQYIGWPAYR-DTPPSKRSLLKVVRRLEKWQEQYDGREGR 1373
Query: 321 MIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQ 379
++HC G GR+GTF A+ + + I+ +D+ +V +R+ + +MV+T EQY F+++
Sbjct: 1374 TVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFHIVKTLRNNKSNMVETLEQYKFVYE 1432
>gi|148539858 protein tyrosine phosphatase, receptor type, T isoform 1
precursor [Homo sapiens]
Length = 1460
Score = 222 bits (566), Expect = 4e-58
Identities = 118/277 (42%), Positives = 167/277 (60%), Gaps = 7/277 (2%)
Query: 107 VQLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDFS 166
+++ D +I M + Y F ++E L G A NR KNRY NI+ YD S
Sbjct: 888 IRVADLLQHITQMKRGQGYGFKEEYEALPE-GQTASWDTAKEDENRNKNRYGNIISYDHS 946
Query: 167 RVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLT 226
RVRL+ ++ + +DYINANYI GY+ P+ YIATQGP+ ET DFW+M+ Q+ S IVM+T
Sbjct: 947 RVRLLVLDGDPHSDYINANYIDGYHRPRHYIATQGPMQETVKDFWRMIWQENSASIVMVT 1006
Query: 227 QCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDDWACRHFRINYA--DEMQDVMHF 284
E RVKC YWP ++ YGDI V +I E ++ R F + E++++ F
Sbjct: 1007 NLVEVGRVKCVRYWP--DDTEVYGDIKVTLIETEPLAEYVIRTFTVQKKGYHEIRELRLF 1064
Query: 285 NYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQH 344
++T+WPDHGVP A +L FV V+ GP+++HCSAG GRTG FIA+D +L
Sbjct: 1065 HFTSWPDHGVPC--YATGLLGFVRQVKFLNPPEAGPIVVHCSAGAGRTGCFIAIDTMLDM 1122
Query: 345 IRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCV 381
+ VDI V E+R+ R+++VQTEEQY+F+H +
Sbjct: 1123 AENEGVVDIFNCVRELRAQRVNLVQTEEQYVFVHDAI 1159
Score = 128 bits (321), Expect = 1e-29
Identities = 78/239 (32%), Positives = 125/239 (52%), Gaps = 12/239 (5%)
Query: 148 LPLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETR 207
LP N KNR ++LP D L+S+ + E ++YINA + + P ++ TQ PLP T
Sbjct: 1218 LPRNHDKNRSMDVLPLDRCLPFLISV-DGESSNYINAALMDSHKQPAAFVVTQHPLPNTV 1276
Query: 208 NDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDDWAC 267
DFW++V +VML + + + C YWP + YG I VE +S + +D
Sbjct: 1277 ADFWRLVFDYNCSSVVMLNEMDTAQF--CMQYWP-EKTSGCYGPIQVEFVSADIDEDIIH 1333
Query: 268 RHFRINYADEMQD----VMHFNYTAWPDHGVPTANAAESILQFVHMV---RQQATKSKGP 320
R FRI QD V H Y WP + T + S+L+ V + ++Q +G
Sbjct: 1334 RIFRICNMARPQDGYRIVQHLQYIGWPAYR-DTPPSKRSLLKVVRRLEKWQEQYDGREGR 1392
Query: 321 MIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQ 379
++HC G GR+GTF A+ + + I+ +D+ +V +R+ + +MV+T EQY F+++
Sbjct: 1393 TVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFHIVKTLRNNKSNMVETLEQYKFVYE 1451
>gi|157419150 protein tyrosine phosphatase, receptor type, M isoform 2
precursor [Homo sapiens]
Length = 1452
Score = 219 bits (558), Expect = 3e-57
Identities = 117/277 (42%), Positives = 162/277 (58%), Gaps = 7/277 (2%)
Query: 107 VQLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDFS 166
+++ D +I M Y F ++E G P +A NR KNRY NI+ YD S
Sbjct: 880 IRVADLLQHITQMKCAEGYGFKEEYESF-FEGQSAPWDSAKKDENRMKNRYGNIIAYDHS 938
Query: 167 RVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLT 226
RVRL ++ + +DYIN NYI GY+ P YIATQGP+ ET DFW+MV + + I+M+T
Sbjct: 939 RVRLQTIEGDTNSDYINGNYIDGYHRPNHYIATQGPMQETIYDFWRMVWHENTASIIMVT 998
Query: 227 QCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDDWACRHFRINY--ADEMQDVMHF 284
E RVKC YWP ++ Y DI V +I E ++ R F + E++++ F
Sbjct: 999 NLVEVGRVKCCKYWP--DDTEIYKDIKVTLIETELLAEYVIRTFAVEKRGVHEIREIRQF 1056
Query: 285 NYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQH 344
++T WPDHGVP A +L FV V+ ++ S GP+++HCSAG GRTG FI +D +L
Sbjct: 1057 HFTGWPDHGVP--YHATGLLGFVRQVKSKSPPSAGPLVVHCSAGAGRTGCFIVIDIMLDM 1114
Query: 345 IRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCV 381
VDI V E+RS R++MVQTEEQY+FIH +
Sbjct: 1115 AEREGVVDIYNCVRELRSRRVNMVQTEEQYVFIHDAI 1151
Score = 122 bits (306), Expect = 6e-28
Identities = 79/240 (32%), Positives = 123/240 (51%), Gaps = 14/240 (5%)
Query: 148 LPLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETR 207
LP N KNR +ILP D L+++ + E ++YINA + Y P +I TQ PLP T
Sbjct: 1210 LPRNHEKNRCMDILPPDRCLPFLITI-DGESSNYINAALMDSYKQPSAFIVTQHPLPNTV 1268
Query: 208 NDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPI-AYGDITVEMISEEEQDDWA 266
DFW++VL +VML + + C YWP E + +G I VE +S + ++D
Sbjct: 1269 KDFWRLVLDYHCTSVVMLNDVDPAQ--LCPQYWP--ENGVHRHGPIQVEFVSADLEEDII 1324
Query: 267 CRHFRINYADEMQD----VMHFNYTAWPDHGVPTANAAESILQFVHMV---RQQATKSKG 319
R FRI A QD V F + WP + T + S L+ + V +++ +G
Sbjct: 1325 SRIFRIYNAARPQDGYRMVQQFQFLGWPMYR-DTPVSKRSFLKLIRQVDKWQEEYNGGEG 1383
Query: 320 PMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQ 379
++HC G GR+GTF A+ + + +R VD+ V +R+ + +MV +QY F ++
Sbjct: 1384 RTVVHCLNGGGRSGTFCAISIVCEMLRHQRTVDVFHAVKTLRNNKPNMVDLLDQYKFCYE 1443
>gi|157419152 protein tyrosine phosphatase, receptor type, M isoform 1
precursor [Homo sapiens]
Length = 1465
Score = 219 bits (558), Expect = 3e-57
Identities = 117/277 (42%), Positives = 162/277 (58%), Gaps = 7/277 (2%)
Query: 107 VQLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDFS 166
+++ D +I M Y F ++E G P +A NR KNRY NI+ YD S
Sbjct: 893 IRVADLLQHITQMKCAEGYGFKEEYESF-FEGQSAPWDSAKKDENRMKNRYGNIIAYDHS 951
Query: 167 RVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLT 226
RVRL ++ + +DYIN NYI GY+ P YIATQGP+ ET DFW+MV + + I+M+T
Sbjct: 952 RVRLQTIEGDTNSDYINGNYIDGYHRPNHYIATQGPMQETIYDFWRMVWHENTASIIMVT 1011
Query: 227 QCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDDWACRHFRINY--ADEMQDVMHF 284
E RVKC YWP ++ Y DI V +I E ++ R F + E++++ F
Sbjct: 1012 NLVEVGRVKCCKYWP--DDTEIYKDIKVTLIETELLAEYVIRTFAVEKRGVHEIREIRQF 1069
Query: 285 NYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQH 344
++T WPDHGVP A +L FV V+ ++ S GP+++HCSAG GRTG FI +D +L
Sbjct: 1070 HFTGWPDHGVP--YHATGLLGFVRQVKSKSPPSAGPLVVHCSAGAGRTGCFIVIDIMLDM 1127
Query: 345 IRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCV 381
VDI V E+RS R++MVQTEEQY+FIH +
Sbjct: 1128 AEREGVVDIYNCVRELRSRRVNMVQTEEQYVFIHDAI 1164
Score = 122 bits (306), Expect = 6e-28
Identities = 79/240 (32%), Positives = 123/240 (51%), Gaps = 14/240 (5%)
Query: 148 LPLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETR 207
LP N KNR +ILP D L+++ + E ++YINA + Y P +I TQ PLP T
Sbjct: 1223 LPRNHEKNRCMDILPPDRCLPFLITI-DGESSNYINAALMDSYKQPSAFIVTQHPLPNTV 1281
Query: 208 NDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPI-AYGDITVEMISEEEQDDWA 266
DFW++VL +VML + + C YWP E + +G I VE +S + ++D
Sbjct: 1282 KDFWRLVLDYHCTSVVMLNDVDPAQ--LCPQYWP--ENGVHRHGPIQVEFVSADLEEDII 1337
Query: 267 CRHFRINYADEMQD----VMHFNYTAWPDHGVPTANAAESILQFVHMV---RQQATKSKG 319
R FRI A QD V F + WP + T + S L+ + V +++ +G
Sbjct: 1338 SRIFRIYNAARPQDGYRMVQQFQFLGWPMYR-DTPVSKRSFLKLIRQVDKWQEEYNGGEG 1396
Query: 320 PMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQ 379
++HC G GR+GTF A+ + + +R VD+ V +R+ + +MV +QY F ++
Sbjct: 1397 RTVVHCLNGGGRSGTFCAISIVCEMLRHQRTVDVFHAVKTLRNNKPNMVDLLDQYKFCYE 1456
>gi|18641364 protein tyrosine phosphatase, receptor type, C isoform
3 precursor [Homo sapiens]
Length = 1256
Score = 216 bits (549), Expect = 4e-56
Identities = 111/280 (39%), Positives = 162/280 (57%), Gaps = 6/280 (2%)
Query: 106 PVQLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDF 165
P+ D K D F +F+ + + P A P N+ KNRY +ILPYD+
Sbjct: 582 PIHADILLETYKRKIADEGRLFLAEFQSIPRVFSKFPIKEARKPFNQNKNRYVDILPYDY 641
Query: 166 SRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVML 225
+RV L +N + G++YINA+YI G+ P++YIA QGP ET +DFW+M+ +QK+ +IVM+
Sbjct: 642 NRVELSEINGDAGSNYINASYIDGFKEPRKYIAAQGPRDETVDDFWRMIWEQKATVIVMV 701
Query: 226 TQCNEKRRVKCDHYWPFTEEPI-AYGDITVEMISEEEQDDWACRHFRINYADEM---QDV 281
T+C E R KC YWP EE A+GD+ V++ + D+ + I E ++V
Sbjct: 702 TRCEEGNRNKCAEYWPSMEEGTRAFGDVVVKINQHKRCPDYIIQKLNIVNKKEKATGREV 761
Query: 282 MHFNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRL 341
H +T+WPDHGVP +L+ V + GP+++HCSAGVGRTGT+I +D +
Sbjct: 762 THIQFTSWPDHGVP--EDPHLLLKLRRRVNAFSNFFSGPIVVHCSAGVGRTGTYIGIDAM 819
Query: 342 LQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCV 381
L+ + VD+ G V ++R R MVQ E QYI IHQ +
Sbjct: 820 LEGLEAENKVDVYGYVVKLRRQRCLMVQVEAQYILIHQAL 859
Score = 140 bits (354), Expect = 2e-33
Identities = 87/260 (33%), Positives = 129/260 (49%), Gaps = 31/260 (11%)
Query: 151 NRCKNRYTNILPYDFSRVRLV-------------------SMNEEEGADYINANYIPGYN 191
N+ KNR +N++PYD++RV L + EE + YINA++I Y
Sbjct: 918 NKSKNRNSNVIPYDYNRVPLKHELEMSKESEHDSDESSDDDSDSEEPSKYINASFIMSYW 977
Query: 192 SPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGD 251
P+ IA QGPL ET DFW+M+ Q+K ++IVMLT+ + C YW E YGD
Sbjct: 978 KPEVMIAAQGPLKETIGDFWQMIFQRKVKVIVMLTELKHGDQEICAQYW--GEGKQTYGD 1035
Query: 252 ITVEMISEEEQDDWACRHFRINYA--DEMQDVMHFNYTAWPDHGVPT-ANAAESILQFVH 308
I V++ ++ + R F + ++ + + V + YT W +P S++Q V
Sbjct: 1036 IEVDLKDTDKSSTYTLRVFELRHSKRKDSRTVYQYQYTNWSVEQLPAEPKELISMIQVVK 1095
Query: 309 MVRQQATKSKG-------PMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMR 361
Q S+G P++IHC G +TG F AL LL+ E VDI +V +R
Sbjct: 1096 QKLPQKNSSEGNKHHKSTPLLIHCRDGSQQTGIFCALLNLLESAETEEVVDIFQVVKALR 1155
Query: 362 SYRMSMVQTEEQYIFIHQCV 381
R MV T EQY F++ +
Sbjct: 1156 KARPGMVSTFEQYQFLYDVI 1175
>gi|18641347 protein tyrosine phosphatase, receptor type, C isoform
1 precursor [Homo sapiens]
Length = 1304
Score = 216 bits (549), Expect = 4e-56
Identities = 111/280 (39%), Positives = 162/280 (57%), Gaps = 6/280 (2%)
Query: 106 PVQLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDF 165
P+ D K D F +F+ + + P A P N+ KNRY +ILPYD+
Sbjct: 630 PIHADILLETYKRKIADEGRLFLAEFQSIPRVFSKFPIKEARKPFNQNKNRYVDILPYDY 689
Query: 166 SRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVML 225
+RV L +N + G++YINA+YI G+ P++YIA QGP ET +DFW+M+ +QK+ +IVM+
Sbjct: 690 NRVELSEINGDAGSNYINASYIDGFKEPRKYIAAQGPRDETVDDFWRMIWEQKATVIVMV 749
Query: 226 TQCNEKRRVKCDHYWPFTEEPI-AYGDITVEMISEEEQDDWACRHFRINYADEM---QDV 281
T+C E R KC YWP EE A+GD+ V++ + D+ + I E ++V
Sbjct: 750 TRCEEGNRNKCAEYWPSMEEGTRAFGDVVVKINQHKRCPDYIIQKLNIVNKKEKATGREV 809
Query: 282 MHFNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRL 341
H +T+WPDHGVP +L+ V + GP+++HCSAGVGRTGT+I +D +
Sbjct: 810 THIQFTSWPDHGVP--EDPHLLLKLRRRVNAFSNFFSGPIVVHCSAGVGRTGTYIGIDAM 867
Query: 342 LQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCV 381
L+ + VD+ G V ++R R MVQ E QYI IHQ +
Sbjct: 868 LEGLEAENKVDVYGYVVKLRRQRCLMVQVEAQYILIHQAL 907
Score = 140 bits (354), Expect = 2e-33
Identities = 87/260 (33%), Positives = 129/260 (49%), Gaps = 31/260 (11%)
Query: 151 NRCKNRYTNILPYDFSRVRLV-------------------SMNEEEGADYINANYIPGYN 191
N+ KNR +N++PYD++RV L + EE + YINA++I Y
Sbjct: 966 NKSKNRNSNVIPYDYNRVPLKHELEMSKESEHDSDESSDDDSDSEEPSKYINASFIMSYW 1025
Query: 192 SPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGD 251
P+ IA QGPL ET DFW+M+ Q+K ++IVMLT+ + C YW E YGD
Sbjct: 1026 KPEVMIAAQGPLKETIGDFWQMIFQRKVKVIVMLTELKHGDQEICAQYW--GEGKQTYGD 1083
Query: 252 ITVEMISEEEQDDWACRHFRINYA--DEMQDVMHFNYTAWPDHGVPT-ANAAESILQFVH 308
I V++ ++ + R F + ++ + + V + YT W +P S++Q V
Sbjct: 1084 IEVDLKDTDKSSTYTLRVFELRHSKRKDSRTVYQYQYTNWSVEQLPAEPKELISMIQVVK 1143
Query: 309 MVRQQATKSKG-------PMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMR 361
Q S+G P++IHC G +TG F AL LL+ E VDI +V +R
Sbjct: 1144 QKLPQKNSSEGNKHHKSTPLLIHCRDGSQQTGIFCALLNLLESAETEEVVDIFQVVKALR 1203
Query: 362 SYRMSMVQTEEQYIFIHQCV 381
R MV T EQY F++ +
Sbjct: 1204 KARPGMVSTFEQYQFLYDVI 1223
>gi|18641362 protein tyrosine phosphatase, receptor type, C isoform
2 precursor [Homo sapiens]
Length = 1143
Score = 216 bits (549), Expect = 4e-56
Identities = 111/280 (39%), Positives = 162/280 (57%), Gaps = 6/280 (2%)
Query: 106 PVQLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDF 165
P+ D K D F +F+ + + P A P N+ KNRY +ILPYD+
Sbjct: 469 PIHADILLETYKRKIADEGRLFLAEFQSIPRVFSKFPIKEARKPFNQNKNRYVDILPYDY 528
Query: 166 SRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVML 225
+RV L +N + G++YINA+YI G+ P++YIA QGP ET +DFW+M+ +QK+ +IVM+
Sbjct: 529 NRVELSEINGDAGSNYINASYIDGFKEPRKYIAAQGPRDETVDDFWRMIWEQKATVIVMV 588
Query: 226 TQCNEKRRVKCDHYWPFTEEPI-AYGDITVEMISEEEQDDWACRHFRINYADEM---QDV 281
T+C E R KC YWP EE A+GD+ V++ + D+ + I E ++V
Sbjct: 589 TRCEEGNRNKCAEYWPSMEEGTRAFGDVVVKINQHKRCPDYIIQKLNIVNKKEKATGREV 648
Query: 282 MHFNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRL 341
H +T+WPDHGVP +L+ V + GP+++HCSAGVGRTGT+I +D +
Sbjct: 649 THIQFTSWPDHGVP--EDPHLLLKLRRRVNAFSNFFSGPIVVHCSAGVGRTGTYIGIDAM 706
Query: 342 LQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCV 381
L+ + VD+ G V ++R R MVQ E QYI IHQ +
Sbjct: 707 LEGLEAENKVDVYGYVVKLRRQRCLMVQVEAQYILIHQAL 746
Score = 140 bits (354), Expect = 2e-33
Identities = 87/260 (33%), Positives = 129/260 (49%), Gaps = 31/260 (11%)
Query: 151 NRCKNRYTNILPYDFSRVRLV-------------------SMNEEEGADYINANYIPGYN 191
N+ KNR +N++PYD++RV L + EE + YINA++I Y
Sbjct: 805 NKSKNRNSNVIPYDYNRVPLKHELEMSKESEHDSDESSDDDSDSEEPSKYINASFIMSYW 864
Query: 192 SPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGD 251
P+ IA QGPL ET DFW+M+ Q+K ++IVMLT+ + C YW E YGD
Sbjct: 865 KPEVMIAAQGPLKETIGDFWQMIFQRKVKVIVMLTELKHGDQEICAQYW--GEGKQTYGD 922
Query: 252 ITVEMISEEEQDDWACRHFRINYA--DEMQDVMHFNYTAWPDHGVPT-ANAAESILQFVH 308
I V++ ++ + R F + ++ + + V + YT W +P S++Q V
Sbjct: 923 IEVDLKDTDKSSTYTLRVFELRHSKRKDSRTVYQYQYTNWSVEQLPAEPKELISMIQVVK 982
Query: 309 MVRQQATKSKG-------PMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMR 361
Q S+G P++IHC G +TG F AL LL+ E VDI +V +R
Sbjct: 983 QKLPQKNSSEGNKHHKSTPLLIHCRDGSQQTGIFCALLNLLESAETEEVVDIFQVVKALR 1042
Query: 362 SYRMSMVQTEEQYIFIHQCV 381
R MV T EQY F++ +
Sbjct: 1043 KARPGMVSTFEQYQFLYDVI 1062
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.324 0.137 0.425
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,742,662
Number of Sequences: 37866
Number of extensions: 627475
Number of successful extensions: 2320
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 113
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 1827
Number of HSP's gapped (non-prelim): 174
length of query: 405
length of database: 18,247,518
effective HSP length: 105
effective length of query: 300
effective length of database: 14,271,588
effective search space: 4281476400
effective search space used: 4281476400
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.5 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.