BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|13677220 receptor-type protein tyrosine phosphatase O isoform d precursor [Homo sapiens] (377 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|13677220 receptor-type protein tyrosine phosphatase O isoform... 773 0.0 gi|13677216 receptor-type protein tyrosine phosphatase O isoform... 773 0.0 gi|4506323 receptor-type protein tyrosine phosphatase O isoform ... 773 0.0 gi|13677222 receptor-type protein tyrosine phosphatase O isoform... 758 0.0 gi|13677218 receptor-type protein tyrosine phosphatase O isoform... 758 0.0 gi|13677214 receptor-type protein tyrosine phosphatase O isoform... 758 0.0 gi|157952215 protein tyrosine phosphatase, receptor type, B isof... 303 2e-82 gi|157952213 protein tyrosine phosphatase, receptor type, B isof... 303 2e-82 gi|222537743 protein tyrosine phosphatase, receptor type, Q [Hom... 286 2e-77 gi|148728162 protein tyrosine phosphatase, receptor type, J isof... 279 3e-75 gi|241896926 protein tyrosine phosphatase, receptor type, H isof... 266 2e-71 gi|241896924 protein tyrosine phosphatase, receptor type, H isof... 266 2e-71 gi|109633041 protein tyrosine phosphatase, receptor type, F isof... 228 9e-60 gi|109633039 protein tyrosine phosphatase, receptor type, F isof... 228 9e-60 gi|4506309 protein tyrosine phosphatase, receptor type, D isofor... 225 4e-59 gi|18860890 protein tyrosine phosphatase, receptor type, D isofo... 225 4e-59 gi|18860892 protein tyrosine phosphatase, receptor type, D isofo... 225 4e-59 gi|18860894 protein tyrosine phosphatase, receptor type, D isofo... 225 4e-59 gi|104487002 protein tyrosine phosphatase, receptor type, D isof... 224 1e-58 gi|104487611 protein tyrosine phosphatase, receptor type, sigma ... 223 2e-58 gi|104487297 protein tyrosine phosphatase, receptor type, sigma ... 223 2e-58 gi|104487295 protein tyrosine phosphatase, receptor type, sigma ... 223 2e-58 gi|104487006 protein tyrosine phosphatase, receptor type, sigma ... 223 2e-58 gi|148539860 protein tyrosine phosphatase, receptor type, T isof... 222 4e-58 gi|148539858 protein tyrosine phosphatase, receptor type, T isof... 222 4e-58 gi|18641364 protein tyrosine phosphatase, receptor type, C isofo... 220 2e-57 gi|18641347 protein tyrosine phosphatase, receptor type, C isofo... 220 2e-57 gi|18641362 protein tyrosine phosphatase, receptor type, C isofo... 220 2e-57 gi|157419150 protein tyrosine phosphatase, receptor type, M isof... 219 3e-57 gi|157419152 protein tyrosine phosphatase, receptor type, M isof... 219 3e-57 >gi|13677220 receptor-type protein tyrosine phosphatase O isoform d precursor [Homo sapiens] Length = 377 Score = 773 bits (1995), Expect = 0.0 Identities = 377/377 (100%), Positives = 377/377 (100%) Query: 1 MVTEMNPNVVVISVLAILSTLLIGLLLVTLIILRKKHLQMARECGAGTFVNFASLERDGK 60 MVTEMNPNVVVISVLAILSTLLIGLLLVTLIILRKKHLQMARECGAGTFVNFASLERDGK Sbjct: 1 MVTEMNPNVVVISVLAILSTLLIGLLLVTLIILRKKHLQMARECGAGTFVNFASLERDGK 60 Query: 61 LPYNWSKNGLKKRKLTNPVQLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADL 120 LPYNWSKNGLKKRKLTNPVQLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADL Sbjct: 61 LPYNWSKNGLKKRKLTNPVQLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADL 120 Query: 121 PLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRN 180 PLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRN Sbjct: 121 PLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRN 180 Query: 181 DFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDDWACR 240 DFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDDWACR Sbjct: 181 DFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDDWACR 240 Query: 241 HFRINYADEMQDVMHFNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSAG 300 HFRINYADEMQDVMHFNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSAG Sbjct: 241 HFRINYADEMQDVMHFNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSAG 300 Query: 301 VGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWMKK 360 VGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWMKK Sbjct: 301 VGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWMKK 360 Query: 361 KQQFCISDVIYENVSKS 377 KQQFCISDVIYENVSKS Sbjct: 361 KQQFCISDVIYENVSKS 377 >gi|13677216 receptor-type protein tyrosine phosphatase O isoform d precursor [Homo sapiens] Length = 377 Score = 773 bits (1995), Expect = 0.0 Identities = 377/377 (100%), Positives = 377/377 (100%) Query: 1 MVTEMNPNVVVISVLAILSTLLIGLLLVTLIILRKKHLQMARECGAGTFVNFASLERDGK 60 MVTEMNPNVVVISVLAILSTLLIGLLLVTLIILRKKHLQMARECGAGTFVNFASLERDGK Sbjct: 1 MVTEMNPNVVVISVLAILSTLLIGLLLVTLIILRKKHLQMARECGAGTFVNFASLERDGK 60 Query: 61 LPYNWSKNGLKKRKLTNPVQLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADL 120 LPYNWSKNGLKKRKLTNPVQLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADL Sbjct: 61 LPYNWSKNGLKKRKLTNPVQLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADL 120 Query: 121 PLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRN 180 PLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRN Sbjct: 121 PLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRN 180 Query: 181 DFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDDWACR 240 DFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDDWACR Sbjct: 181 DFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDDWACR 240 Query: 241 HFRINYADEMQDVMHFNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSAG 300 HFRINYADEMQDVMHFNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSAG Sbjct: 241 HFRINYADEMQDVMHFNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSAG 300 Query: 301 VGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWMKK 360 VGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWMKK Sbjct: 301 VGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWMKK 360 Query: 361 KQQFCISDVIYENVSKS 377 KQQFCISDVIYENVSKS Sbjct: 361 KQQFCISDVIYENVSKS 377 >gi|4506323 receptor-type protein tyrosine phosphatase O isoform b precursor [Homo sapiens] Length = 1188 Score = 773 bits (1995), Expect = 0.0 Identities = 377/377 (100%), Positives = 377/377 (100%) Query: 1 MVTEMNPNVVVISVLAILSTLLIGLLLVTLIILRKKHLQMARECGAGTFVNFASLERDGK 60 MVTEMNPNVVVISVLAILSTLLIGLLLVTLIILRKKHLQMARECGAGTFVNFASLERDGK Sbjct: 812 MVTEMNPNVVVISVLAILSTLLIGLLLVTLIILRKKHLQMARECGAGTFVNFASLERDGK 871 Query: 61 LPYNWSKNGLKKRKLTNPVQLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADL 120 LPYNWSKNGLKKRKLTNPVQLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADL Sbjct: 872 LPYNWSKNGLKKRKLTNPVQLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADL 931 Query: 121 PLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRN 180 PLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRN Sbjct: 932 PLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRN 991 Query: 181 DFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDDWACR 240 DFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDDWACR Sbjct: 992 DFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDDWACR 1051 Query: 241 HFRINYADEMQDVMHFNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSAG 300 HFRINYADEMQDVMHFNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSAG Sbjct: 1052 HFRINYADEMQDVMHFNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSAG 1111 Query: 301 VGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWMKK 360 VGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWMKK Sbjct: 1112 VGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWMKK 1171 Query: 361 KQQFCISDVIYENVSKS 377 KQQFCISDVIYENVSKS Sbjct: 1172 KQQFCISDVIYENVSKS 1188 >gi|13677222 receptor-type protein tyrosine phosphatase O isoform c precursor [Homo sapiens] Length = 405 Score = 758 bits (1956), Expect = 0.0 Identities = 377/405 (93%), Positives = 377/405 (93%), Gaps = 28/405 (6%) Query: 1 MVTEMNPNVVVISVLAILSTLLIGLLLVTLIILRKKHLQMARECGAGTFVNFASLERDGK 60 MVTEMNPNVVVISVLAILSTLLIGLLLVTLIILRKKHLQMARECGAGTFVNFASLERDGK Sbjct: 1 MVTEMNPNVVVISVLAILSTLLIGLLLVTLIILRKKHLQMARECGAGTFVNFASLERDGK 60 Query: 61 LPYNW----------------------------SKNGLKKRKLTNPVQLDDFDAYIKDMA 92 LPYNW SKNGLKKRKLTNPVQLDDFDAYIKDMA Sbjct: 61 LPYNWRRSIFAFLTLLPSCLWTDYLLAFYINPWSKNGLKKRKLTNPVQLDDFDAYIKDMA 120 Query: 93 KDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGAD 152 KDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGAD Sbjct: 121 KDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGAD 180 Query: 153 YINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYW 212 YINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYW Sbjct: 181 YINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYW 240 Query: 213 PFTEEPIAYGDITVEMISEEEQDDWACRHFRINYADEMQDVMHFNYTAWPDHGVPTANAA 272 PFTEEPIAYGDITVEMISEEEQDDWACRHFRINYADEMQDVMHFNYTAWPDHGVPTANAA Sbjct: 241 PFTEEPIAYGDITVEMISEEEQDDWACRHFRINYADEMQDVMHFNYTAWPDHGVPTANAA 300 Query: 273 ESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEM 332 ESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEM Sbjct: 301 ESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEM 360 Query: 333 RSYRMSMVQTEEQYIFIHQCVQLMWMKKKQQFCISDVIYENVSKS 377 RSYRMSMVQTEEQYIFIHQCVQLMWMKKKQQFCISDVIYENVSKS Sbjct: 361 RSYRMSMVQTEEQYIFIHQCVQLMWMKKKQQFCISDVIYENVSKS 405 >gi|13677218 receptor-type protein tyrosine phosphatase O isoform c precursor [Homo sapiens] Length = 405 Score = 758 bits (1956), Expect = 0.0 Identities = 377/405 (93%), Positives = 377/405 (93%), Gaps = 28/405 (6%) Query: 1 MVTEMNPNVVVISVLAILSTLLIGLLLVTLIILRKKHLQMARECGAGTFVNFASLERDGK 60 MVTEMNPNVVVISVLAILSTLLIGLLLVTLIILRKKHLQMARECGAGTFVNFASLERDGK Sbjct: 1 MVTEMNPNVVVISVLAILSTLLIGLLLVTLIILRKKHLQMARECGAGTFVNFASLERDGK 60 Query: 61 LPYNW----------------------------SKNGLKKRKLTNPVQLDDFDAYIKDMA 92 LPYNW SKNGLKKRKLTNPVQLDDFDAYIKDMA Sbjct: 61 LPYNWRRSIFAFLTLLPSCLWTDYLLAFYINPWSKNGLKKRKLTNPVQLDDFDAYIKDMA 120 Query: 93 KDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGAD 152 KDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGAD Sbjct: 121 KDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGAD 180 Query: 153 YINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYW 212 YINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYW Sbjct: 181 YINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYW 240 Query: 213 PFTEEPIAYGDITVEMISEEEQDDWACRHFRINYADEMQDVMHFNYTAWPDHGVPTANAA 272 PFTEEPIAYGDITVEMISEEEQDDWACRHFRINYADEMQDVMHFNYTAWPDHGVPTANAA Sbjct: 241 PFTEEPIAYGDITVEMISEEEQDDWACRHFRINYADEMQDVMHFNYTAWPDHGVPTANAA 300 Query: 273 ESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEM 332 ESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEM Sbjct: 301 ESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEM 360 Query: 333 RSYRMSMVQTEEQYIFIHQCVQLMWMKKKQQFCISDVIYENVSKS 377 RSYRMSMVQTEEQYIFIHQCVQLMWMKKKQQFCISDVIYENVSKS Sbjct: 361 RSYRMSMVQTEEQYIFIHQCVQLMWMKKKQQFCISDVIYENVSKS 405 >gi|13677214 receptor-type protein tyrosine phosphatase O isoform a precursor [Homo sapiens] Length = 1216 Score = 758 bits (1956), Expect = 0.0 Identities = 377/405 (93%), Positives = 377/405 (93%), Gaps = 28/405 (6%) Query: 1 MVTEMNPNVVVISVLAILSTLLIGLLLVTLIILRKKHLQMARECGAGTFVNFASLERDGK 60 MVTEMNPNVVVISVLAILSTLLIGLLLVTLIILRKKHLQMARECGAGTFVNFASLERDGK Sbjct: 812 MVTEMNPNVVVISVLAILSTLLIGLLLVTLIILRKKHLQMARECGAGTFVNFASLERDGK 871 Query: 61 LPYNW----------------------------SKNGLKKRKLTNPVQLDDFDAYIKDMA 92 LPYNW SKNGLKKRKLTNPVQLDDFDAYIKDMA Sbjct: 872 LPYNWRRSIFAFLTLLPSCLWTDYLLAFYINPWSKNGLKKRKLTNPVQLDDFDAYIKDMA 931 Query: 93 KDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGAD 152 KDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGAD Sbjct: 932 KDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGAD 991 Query: 153 YINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYW 212 YINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYW Sbjct: 992 YINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYW 1051 Query: 213 PFTEEPIAYGDITVEMISEEEQDDWACRHFRINYADEMQDVMHFNYTAWPDHGVPTANAA 272 PFTEEPIAYGDITVEMISEEEQDDWACRHFRINYADEMQDVMHFNYTAWPDHGVPTANAA Sbjct: 1052 PFTEEPIAYGDITVEMISEEEQDDWACRHFRINYADEMQDVMHFNYTAWPDHGVPTANAA 1111 Query: 273 ESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEM 332 ESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEM Sbjct: 1112 ESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEM 1171 Query: 333 RSYRMSMVQTEEQYIFIHQCVQLMWMKKKQQFCISDVIYENVSKS 377 RSYRMSMVQTEEQYIFIHQCVQLMWMKKKQQFCISDVIYENVSKS Sbjct: 1172 RSYRMSMVQTEEQYIFIHQCVQLMWMKKKQQFCISDVIYENVSKS 1216 >gi|157952215 protein tyrosine phosphatase, receptor type, B isoform a [Homo sapiens] Length = 2215 Score = 303 bits (776), Expect = 2e-82 Identities = 165/364 (45%), Positives = 234/364 (64%), Gaps = 17/364 (4%) Query: 22 LIGLLL--VTLIILRKKHLQMARECGAGTFVNFASLERDGKLPYNWSKNGLKKRKLTNPV 79 LIG+L+ V L+I R+K + RE + S+ RD L + + RK + P+ Sbjct: 1847 LIGMLVAVVALLICRQK-VSHGRERPSARL----SIRRDRPLSVHLNLGQKGNRKTSCPI 1901 Query: 80 QLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDFSR 139 +++ F+ + + DS+Y S ++EELK +G + A LP NR KNRY NILPYD +R Sbjct: 1902 KINQFEGHFMKLQADSNYLLSKEYEELKDVGRNQSCDIALLPENRGKNRYNNILPYDATR 1961 Query: 140 VRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQ 199 V+L +++++ +DYINA+YIPG N +EYI TQGPLP T++DFWKMV +Q IVM+TQ Sbjct: 1962 VKLSNVDDDPCSDYINASYIPGNNFRREYIVTQGPLPGTKDDFWKMVWEQNVHNIVMVTQ 2021 Query: 200 CNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDDWACRHFRI---NYADEMQDVMHF 256 C EK RVKCDHYWP ++ + YGD+ ++M+SE +W R F+I D + + HF Sbjct: 2022 CVEKGRVKCDHYWPADQDSLYYGDLILQMLSESVLPEWTIREFKICGEEQLDAHRLIRHF 2081 Query: 257 NYTAWPDHGVPTANAAESILQFVHMVRQQATKS--KGPMIIHCSAGVGRTGTFIALDRLL 314 +YT WPDHGVP +S++QFV VR +S GP ++HCSAGVGRTGTFIALDR+L Sbjct: 2082 HYTVWPDHGVP--ETTQSLIQFVRTVRDYINRSPGAGPTVVHCSAGVGRTGTFIALDRIL 2139 Query: 315 QHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWMKKK---QQFCISDVIY 371 Q + + VDI G V ++R +R+ MVQTE QY+++HQCV+ + +K +Q IY Sbjct: 2140 QQLDSKDSVDIYGAVHDLRLHRVHMVQTECQYVYLHQCVRDVLRARKLRSEQENPLFPIY 2199 Query: 372 ENVS 375 ENV+ Sbjct: 2200 ENVN 2203 >gi|157952213 protein tyrosine phosphatase, receptor type, B isoform b precursor [Homo sapiens] Length = 1997 Score = 303 bits (776), Expect = 2e-82 Identities = 165/364 (45%), Positives = 234/364 (64%), Gaps = 17/364 (4%) Query: 22 LIGLLL--VTLIILRKKHLQMARECGAGTFVNFASLERDGKLPYNWSKNGLKKRKLTNPV 79 LIG+L+ V L+I R+K + RE + S+ RD L + + RK + P+ Sbjct: 1629 LIGMLVAVVALLICRQK-VSHGRERPSARL----SIRRDRPLSVHLNLGQKGNRKTSCPI 1683 Query: 80 QLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDFSR 139 +++ F+ + + DS+Y S ++EELK +G + A LP NR KNRY NILPYD +R Sbjct: 1684 KINQFEGHFMKLQADSNYLLSKEYEELKDVGRNQSCDIALLPENRGKNRYNNILPYDATR 1743 Query: 140 VRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQ 199 V+L +++++ +DYINA+YIPG N +EYI TQGPLP T++DFWKMV +Q IVM+TQ Sbjct: 1744 VKLSNVDDDPCSDYINASYIPGNNFRREYIVTQGPLPGTKDDFWKMVWEQNVHNIVMVTQ 1803 Query: 200 CNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDDWACRHFRI---NYADEMQDVMHF 256 C EK RVKCDHYWP ++ + YGD+ ++M+SE +W R F+I D + + HF Sbjct: 1804 CVEKGRVKCDHYWPADQDSLYYGDLILQMLSESVLPEWTIREFKICGEEQLDAHRLIRHF 1863 Query: 257 NYTAWPDHGVPTANAAESILQFVHMVRQQATKS--KGPMIIHCSAGVGRTGTFIALDRLL 314 +YT WPDHGVP +S++QFV VR +S GP ++HCSAGVGRTGTFIALDR+L Sbjct: 1864 HYTVWPDHGVP--ETTQSLIQFVRTVRDYINRSPGAGPTVVHCSAGVGRTGTFIALDRIL 1921 Query: 315 QHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWMKKK---QQFCISDVIY 371 Q + + VDI G V ++R +R+ MVQTE QY+++HQCV+ + +K +Q IY Sbjct: 1922 QQLDSKDSVDIYGAVHDLRLHRVHMVQTECQYVYLHQCVRDVLRARKLRSEQENPLFPIY 1981 Query: 372 ENVS 375 ENV+ Sbjct: 1982 ENVN 1985 >gi|222537743 protein tyrosine phosphatase, receptor type, Q [Homo sapiens] Length = 2299 Score = 286 bits (732), Expect = 2e-77 Identities = 156/388 (40%), Positives = 222/388 (57%), Gaps = 20/388 (5%) Query: 2 VTEMNPNVVVISVLAILSTLLIGLLLVTLIILRKKHLQ-----------MARECGAGTFV 50 ++E +++ L ILS +L+G + +R+K + + + + Sbjct: 1899 LSERTVEIILSVTLCILSIILLGTAIFAFARIRQKQKEGGTYSPQDAEIIDTKLKLDQLI 1958 Query: 51 NFASLE-RDGKLPYNWSKNGLKKRKLTNPVQLDDFDAYIKDMAKDSDYKFSLQFEELKLI 109 A LE +D +L L RK P+ F +++++ +++ KF +F EL Sbjct: 1959 TVADLELKDERLT-----RLLSYRKSIKPISKKSFLQHVEELCTNNNLKFQEEFSELPKF 2013 Query: 110 GLDIPHFAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYI 169 D+ ADLP NR KNR+ NI PY+ +RV+L++ G+DYINA+YI GY P E+I Sbjct: 2014 LQDLSSTDADLPWNRAKNRFPNIKPYNNNRVKLIADASVPGSDYINASYISGYLCPNEFI 2073 Query: 170 ATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPI-AYGDITVEM 228 ATQGPLP T DFW+MV + +++ +VMLTQC EK R++C YWP +P+ +GDI + Sbjct: 2074 ATQGPLPGTVGDFWRMVWETRAKTLVMLTQCFEKGRIRCHQYWPEDNKPVTVFGDIVITK 2133 Query: 229 ISEEEQDDWACRHFRINYADEMQDVMHFNYTAWPDHGVPTANAAESILQFVHMVRQQATK 288 + E+ Q DW R +I + V N+TAWP+HGVP +A ++ FV +VR Sbjct: 2134 LMEDVQIDWTIRDLKIERHGDCMTVRQCNFTAWPEHGVPENSA--PLIHFVKLVRASRAH 2191 Query: 289 SKGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIF 348 PMI+HCSAGVGRTG FIALD L QHI DH+FVDI GLV+E+RS RM MVQ QYIF Sbjct: 2192 DTTPMIVHCSAGVGRTGVFIALDHLTQHINDHDFVDIYGLVAELRSERMCMVQNLAQYIF 2251 Query: 349 IHQCVQLMWMKKKQQFCISDVIYENVSK 376 +HQC+ + K I V Y + K Sbjct: 2252 LHQCILDLLSNKGSNQPICFVNYSALQK 2279 >gi|148728162 protein tyrosine phosphatase, receptor type, J isoform 1 precursor [Homo sapiens] Length = 1337 Score = 279 bits (714), Expect = 3e-75 Identities = 145/334 (43%), Positives = 220/334 (65%), Gaps = 14/334 (4%) Query: 47 GTFVNFASLERDGKL-PYNWSKNGLKKRKLTNPVQLDDFDAYIKDMAKDSDYKFSLQFEE 105 G F+ + +D K ++S+ KK KL +++++F+AY K DS+ F+ ++E+ Sbjct: 991 GGFIFWRKKRKDAKNNEVSFSQIKPKKSKL---IRVENFEAYFKKQQADSNCGFAEEYED 1047 Query: 106 LKLIGLDIPHFAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSP 165 LKL+G+ P +AA+L NR KNRY N+LPYD SRV+L S+ DYINANY+PGY+S Sbjct: 1048 LKLVGISQPKYAAELAENRGKNRYNNVLPYDISRVKL-SVQTHSTDDYINANYMPGYHSK 1106 Query: 166 QEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDIT 225 +++IATQGPLP T DFW+MV ++ I+MLT+C E+ R KC+ YWP +++ YGDIT Sbjct: 1107 KDFIATQGPLPNTLKDFWRMVWEKNVYAIIMLTKCVEQGRTKCEEYWP-SKQAQDYGDIT 1165 Query: 226 VEMISEEEQDDWACRHFRIN--YADEMQDVMHFNYTAWPDHGVPTANAAESILQFVHMVR 283 V M SE +W R F + E + F++T+WPDHGVP + + ++ F ++VR Sbjct: 1166 VAMTSEIVLPEWTIRDFTVKNIQTSESHPLRQFHFTSWPDHGVP--DTTDLLINFRYLVR 1223 Query: 284 QQATKS--KGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQ 341 +S + P+++HCSAGVGRTGTFIA+DRL+ I + VD+ G+V ++R +R MVQ Sbjct: 1224 DYMKQSPPESPILVHCSAGVGRTGTFIAIDRLIYQIENENTVDVYGIVYDLRMHRPLMVQ 1283 Query: 342 TEEQYIFIHQCVQLMWMKKKQQFCISDVIYENVS 375 TE+QY+F++QCV + + + Q+ D+IY+N + Sbjct: 1284 TEDQYVFLNQCV--LDIVRSQKDSKVDLIYQNTT 1315 >gi|241896926 protein tyrosine phosphatase, receptor type, H isoform 2 precursor [Homo sapiens] Length = 937 Score = 266 bits (681), Expect = 2e-71 Identities = 131/300 (43%), Positives = 189/300 (63%), Gaps = 6/300 (2%) Query: 79 VQLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDFS 138 + +DF +++ +DS+ F+ ++++L L+G A N KNRY N+LPYD+S Sbjct: 622 IPAEDFADHVRKNERDSNCGFADKYQQLSLVGHSQSQMVASASENNAKNRYRNVLPYDWS 681 Query: 139 RVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLT 198 RV L ++EE G+DYINA+++PG SPQE+IATQGPLP+T DFW++V +Q+S +VMLT Sbjct: 682 RVPLKPIHEEPGSDYINASFMPGLWSPQEFIATQGPLPQTVGDFWRLVWEQQSHTLVMLT 741 Query: 199 QCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDDWACRHFRINYADEMQ--DVMHF 256 C E RVKC+HYWP +P +G + V ++ EE ++W R + +E + V F Sbjct: 742 NCMEAGRVKCEHYWPLDSQPCTHGHLRVTLVGEEVMENWTVRELLLLQVEEQKTLSVRQF 801 Query: 257 NYTAWPDHGVPTANAAESILQFVHMVRQ--QATKSKGPMIIHCSAGVGRTGTFIALDRLL 314 +Y AWPDHGVP ++ +++L F M+RQ T GP I+HCSAGVGRTGT IALD LL Sbjct: 802 HYQAWPDHGVP--SSPDTLLAFWRMLRQWLDQTMEGGPPIVHCSAGVGRTGTLIALDVLL 859 Query: 315 QHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWMKKKQQFCISDVIYENV 374 + ++ + V +MR R MVQTE QY+F+HQC+ + Q +V YE+V Sbjct: 860 RQLQSEGLLGPFSFVRKMRESRPLMVQTEAQYVFLHQCILRFLQQSAQAPAEKEVPYEDV 919 >gi|241896924 protein tyrosine phosphatase, receptor type, H isoform 1 precursor [Homo sapiens] Length = 1115 Score = 266 bits (681), Expect = 2e-71 Identities = 131/300 (43%), Positives = 189/300 (63%), Gaps = 6/300 (2%) Query: 79 VQLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDFS 138 + +DF +++ +DS+ F+ ++++L L+G A N KNRY N+LPYD+S Sbjct: 800 IPAEDFADHVRKNERDSNCGFADKYQQLSLVGHSQSQMVASASENNAKNRYRNVLPYDWS 859 Query: 139 RVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLT 198 RV L ++EE G+DYINA+++PG SPQE+IATQGPLP+T DFW++V +Q+S +VMLT Sbjct: 860 RVPLKPIHEEPGSDYINASFMPGLWSPQEFIATQGPLPQTVGDFWRLVWEQQSHTLVMLT 919 Query: 199 QCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDDWACRHFRINYADEMQ--DVMHF 256 C E RVKC+HYWP +P +G + V ++ EE ++W R + +E + V F Sbjct: 920 NCMEAGRVKCEHYWPLDSQPCTHGHLRVTLVGEEVMENWTVRELLLLQVEEQKTLSVRQF 979 Query: 257 NYTAWPDHGVPTANAAESILQFVHMVRQ--QATKSKGPMIIHCSAGVGRTGTFIALDRLL 314 +Y AWPDHGVP ++ +++L F M+RQ T GP I+HCSAGVGRTGT IALD LL Sbjct: 980 HYQAWPDHGVP--SSPDTLLAFWRMLRQWLDQTMEGGPPIVHCSAGVGRTGTLIALDVLL 1037 Query: 315 QHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWMKKKQQFCISDVIYENV 374 + ++ + V +MR R MVQTE QY+F+HQC+ + Q +V YE+V Sbjct: 1038 RQLQSEGLLGPFSFVRKMRESRPLMVQTEAQYVFLHQCILRFLQQSAQAPAEKEVPYEDV 1097 >gi|109633041 protein tyrosine phosphatase, receptor type, F isoform 1 precursor [Homo sapiens] Length = 1907 Score = 228 bits (580), Expect = 9e-60 Identities = 129/344 (37%), Positives = 193/344 (56%), Gaps = 14/344 (4%) Query: 17 ILSTLLIGLLLVTLIILRKKHLQMARECGAGTFVNFASLERDGKLPY-----NWSKNGLK 71 +L+ +LI L+++ +++ ++K + SL P N+ G++ Sbjct: 1268 VLAVILIILIVIAILLFKRKRTHSPSSKDEQSIGLKDSLLAHSSDPVEMRRLNYQTPGMR 1327 Query: 72 KRKLTNPVQLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTN 131 P+ + D I+ + + KFS ++E + G ++L +N+ KNRY N Sbjct: 1328 DHP---PIPITDLADNIERLKANDGLKFSQEYESIDP-GQQFTWENSNLEVNKPKNRYAN 1383 Query: 132 ILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKS 191 ++ YD SRV L S++ G+DYINANYI GY YIATQGPLPET DFW+MV +Q++ Sbjct: 1384 VIAYDHSRVILTSIDGVPGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRT 1443 Query: 192 QIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDDWACRHFRINY--ADE 249 +VM+T+ EK RVKCD YWP G I V ++ E + R F ++ + E Sbjct: 1444 ATVVMMTRLEEKSRVKCDQYWP-ARGTETCGLIQVTLLDTVELATYTVRTFALHKSGSSE 1502 Query: 250 MQDVMHFNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIA 309 +++ F + AWPDHGVP IL F+ V+ GPM++HCSAGVGRTG FI Sbjct: 1503 KRELRQFQFMAWPDHGVP--EYPTPILAFLRRVKACNPLDAGPMVVHCSAGVGRTGCFIV 1560 Query: 310 LDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCV 353 +D +L+ ++ + VDI G V+ MRS R MVQTE+QY+FIH+ + Sbjct: 1561 IDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEAL 1604 Score = 188 bits (477), Expect = 8e-48 Identities = 103/251 (41%), Positives = 145/251 (57%), Gaps = 13/251 (5%) Query: 105 ELKLIGLDIPH----FAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIP 160 E KL+ H +A+LP N+ KNR NI+PY+ +RV L + EG+DYINA+++ Sbjct: 1642 EFKLLASSKAHTSRFISANLPCNKFKNRLVNIMPYELTRVCLQPIRGVEGSDYINASFLD 1701 Query: 161 GYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIA 220 GY + YIATQGPL E+ DFW+M+ + S IIVMLT+ E R KC YWP E Sbjct: 1702 GYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWP-AERSAR 1760 Query: 221 YGDITVEMISEEEQDDWACRHFRINYADEMQD--VMHFNYTAWPDHGVPTANAAESILQF 278 Y V+ ++E + R F++ A + Q + F +T WP+ GVP E + F Sbjct: 1761 YQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVP--KTGEGFIDF 1818 Query: 279 ---VHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSY 335 VH ++Q + GP+ +HCSAGVGRTG FI L +L+ +R VD+ V +R+ Sbjct: 1819 IGQVHKTKEQFGQD-GPITVHCSAGVGRTGVFITLSIVLERMRYEGVVDMFQTVKTLRTQ 1877 Query: 336 RMSMVQTEEQY 346 R +MVQTE+QY Sbjct: 1878 RPAMVQTEDQY 1888 >gi|109633039 protein tyrosine phosphatase, receptor type, F isoform 2 precursor [Homo sapiens] Length = 1898 Score = 228 bits (580), Expect = 9e-60 Identities = 129/344 (37%), Positives = 193/344 (56%), Gaps = 14/344 (4%) Query: 17 ILSTLLIGLLLVTLIILRKKHLQMARECGAGTFVNFASLERDGKLPY-----NWSKNGLK 71 +L+ +LI L+++ +++ ++K + SL P N+ G++ Sbjct: 1259 VLAVILIILIVIAILLFKRKRTHSPSSKDEQSIGLKDSLLAHSSDPVEMRRLNYQTPGMR 1318 Query: 72 KRKLTNPVQLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTN 131 P+ + D I+ + + KFS ++E + G ++L +N+ KNRY N Sbjct: 1319 DHP---PIPITDLADNIERLKANDGLKFSQEYESIDP-GQQFTWENSNLEVNKPKNRYAN 1374 Query: 132 ILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKS 191 ++ YD SRV L S++ G+DYINANYI GY YIATQGPLPET DFW+MV +Q++ Sbjct: 1375 VIAYDHSRVILTSIDGVPGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRT 1434 Query: 192 QIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDDWACRHFRINY--ADE 249 +VM+T+ EK RVKCD YWP G I V ++ E + R F ++ + E Sbjct: 1435 ATVVMMTRLEEKSRVKCDQYWP-ARGTETCGLIQVTLLDTVELATYTVRTFALHKSGSSE 1493 Query: 250 MQDVMHFNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIA 309 +++ F + AWPDHGVP IL F+ V+ GPM++HCSAGVGRTG FI Sbjct: 1494 KRELRQFQFMAWPDHGVP--EYPTPILAFLRRVKACNPLDAGPMVVHCSAGVGRTGCFIV 1551 Query: 310 LDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCV 353 +D +L+ ++ + VDI G V+ MRS R MVQTE+QY+FIH+ + Sbjct: 1552 IDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEAL 1595 Score = 188 bits (477), Expect = 8e-48 Identities = 103/251 (41%), Positives = 145/251 (57%), Gaps = 13/251 (5%) Query: 105 ELKLIGLDIPH----FAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIP 160 E KL+ H +A+LP N+ KNR NI+PY+ +RV L + EG+DYINA+++ Sbjct: 1633 EFKLLASSKAHTSRFISANLPCNKFKNRLVNIMPYELTRVCLQPIRGVEGSDYINASFLD 1692 Query: 161 GYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIA 220 GY + YIATQGPL E+ DFW+M+ + S IIVMLT+ E R KC YWP E Sbjct: 1693 GYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWP-AERSAR 1751 Query: 221 YGDITVEMISEEEQDDWACRHFRINYADEMQD--VMHFNYTAWPDHGVPTANAAESILQF 278 Y V+ ++E + R F++ A + Q + F +T WP+ GVP E + F Sbjct: 1752 YQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVP--KTGEGFIDF 1809 Query: 279 ---VHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSY 335 VH ++Q + GP+ +HCSAGVGRTG FI L +L+ +R VD+ V +R+ Sbjct: 1810 IGQVHKTKEQFGQD-GPITVHCSAGVGRTGVFITLSIVLERMRYEGVVDMFQTVKTLRTQ 1868 Query: 336 RMSMVQTEEQY 346 R +MVQTE+QY Sbjct: 1869 RPAMVQTEDQY 1879 >gi|4506309 protein tyrosine phosphatase, receptor type, D isoform 1 precursor [Homo sapiens] Length = 1912 Score = 225 bits (574), Expect = 4e-59 Identities = 130/355 (36%), Positives = 203/355 (57%), Gaps = 26/355 (7%) Query: 10 VVISVLAILSTLLIGLLLVTLIILRKKHLQMARECGAGTFVNFASLERDGKLPYNWSKNG 69 VV VLA++ +I +++ L+ RK+ +R+ +S+ + ++P + + Sbjct: 1270 VVGPVLAVV--FIICIVIAILLYKRKRAESDSRK---------SSIPNNKEIPSHHPTDP 1318 Query: 70 LKKRKLT---------NPVQLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADL 120 ++ R+L P+ + + +I+ + + + KFS ++E + G ++L Sbjct: 1319 VELRRLNFQTPGMASHPPIPILELADHIERLKANDNLKFSQEYESIDP-GQQFTWEHSNL 1377 Query: 121 PLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRN 180 +N+ KNRY N++ YD SRV L ++ G+DY+NANYI GY YIATQG LPET Sbjct: 1378 EVNKPKNRYANVIAYDHSRVLLSAIEGIPGSDYVNANYIDGYRKQNAYIATQGSLPETFG 1437 Query: 181 DFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDDWACR 240 DFW+M+ +Q+S +VM+T+ E+ RVKCD YWP + +G + V ++ E + R Sbjct: 1438 DFWRMIWEQRSATVVMMTKLEERSRVKCDQYWP-SRGTETHGLVQVTLLDTVELATYCVR 1496 Query: 241 HFRI--NYADEMQDVMHFNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCS 298 F + N + E ++V F +TAWPDHGVP L F+ V+ GPM++HCS Sbjct: 1497 TFALYKNGSSEKREVRQFQFTAWPDHGVP--EHPTPFLAFLRRVKTCNPPDAGPMVVHCS 1554 Query: 299 AGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCV 353 AGVGRTG FI +D +L+ I+ + VDI G V+ MR+ R MVQTE+QYIFIH + Sbjct: 1555 AGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRAQRNYMVQTEDQYIFIHDAL 1609 Score = 191 bits (484), Expect = 1e-48 Identities = 103/240 (42%), Positives = 144/240 (60%), Gaps = 9/240 (3%) Query: 117 AADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLP 176 +A+LP N+ KNR NI+PY+ +RV L + EG+DYINA++I GY + YIATQGPL Sbjct: 1663 SANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLA 1722 Query: 177 ETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDD 236 ET DFW+M+ + S I+VMLT+ E R KC YWP E Y V+ ++E Sbjct: 1723 ETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWP-AERSARYQYFVVDPMAEYNMPQ 1781 Query: 237 WACRHFRINYADEMQD--VMHFNYTAWPDHGVPTANAAESILQF---VHMVRQQATKSKG 291 + R F++ A + Q V F +T WP+ GVP + E + F VH ++Q + G Sbjct: 1782 YILREFKVTDARDGQSRTVRQFQFTDWPEQGVP--KSGEGFIDFIGQVHKTKEQFGQD-G 1838 Query: 292 PMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQ 351 P+ +HCSAGVGRTG FI L +L+ +R VDI V +R+ R +MVQTE+QY F ++ Sbjct: 1839 PISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDQYQFSYR 1898 >gi|18860890 protein tyrosine phosphatase, receptor type, D isoform 2 precursor [Homo sapiens] Length = 1899 Score = 225 bits (574), Expect = 4e-59 Identities = 130/355 (36%), Positives = 203/355 (57%), Gaps = 26/355 (7%) Query: 10 VVISVLAILSTLLIGLLLVTLIILRKKHLQMARECGAGTFVNFASLERDGKLPYNWSKNG 69 VV VLA++ +I +++ L+ RK+ +R+ +S+ + ++P + + Sbjct: 1257 VVGPVLAVV--FIICIVIAILLYKRKRAESDSRK---------SSIPNNKEIPSHHPTDP 1305 Query: 70 LKKRKLT---------NPVQLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADL 120 ++ R+L P+ + + +I+ + + + KFS ++E + G ++L Sbjct: 1306 VELRRLNFQTPGMASHPPIPILELADHIERLKANDNLKFSQEYESIDP-GQQFTWEHSNL 1364 Query: 121 PLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRN 180 +N+ KNRY N++ YD SRV L ++ G+DY+NANYI GY YIATQG LPET Sbjct: 1365 EVNKPKNRYANVIAYDHSRVLLSAIEGIPGSDYVNANYIDGYRKQNAYIATQGSLPETFG 1424 Query: 181 DFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDDWACR 240 DFW+M+ +Q+S +VM+T+ E+ RVKCD YWP + +G + V ++ E + R Sbjct: 1425 DFWRMIWEQRSATVVMMTKLEERSRVKCDQYWP-SRGTETHGLVQVTLLDTVELATYCVR 1483 Query: 241 HFRI--NYADEMQDVMHFNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCS 298 F + N + E ++V F +TAWPDHGVP L F+ V+ GPM++HCS Sbjct: 1484 TFALYKNGSSEKREVRQFQFTAWPDHGVP--EHPTPFLAFLRRVKTCNPPDAGPMVVHCS 1541 Query: 299 AGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCV 353 AGVGRTG FI +D +L+ I+ + VDI G V+ MR+ R MVQTE+QYIFIH + Sbjct: 1542 AGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRAQRNYMVQTEDQYIFIHDAL 1596 Score = 191 bits (484), Expect = 1e-48 Identities = 103/240 (42%), Positives = 144/240 (60%), Gaps = 9/240 (3%) Query: 117 AADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLP 176 +A+LP N+ KNR NI+PY+ +RV L + EG+DYINA++I GY + YIATQGPL Sbjct: 1650 SANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLA 1709 Query: 177 ETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDD 236 ET DFW+M+ + S I+VMLT+ E R KC YWP E Y V+ ++E Sbjct: 1710 ETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWP-AERSARYQYFVVDPMAEYNMPQ 1768 Query: 237 WACRHFRINYADEMQD--VMHFNYTAWPDHGVPTANAAESILQF---VHMVRQQATKSKG 291 + R F++ A + Q V F +T WP+ GVP + E + F VH ++Q + G Sbjct: 1769 YILREFKVTDARDGQSRTVRQFQFTDWPEQGVP--KSGEGFIDFIGQVHKTKEQFGQD-G 1825 Query: 292 PMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQ 351 P+ +HCSAGVGRTG FI L +L+ +R VDI V +R+ R +MVQTE+QY F ++ Sbjct: 1826 PISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDQYQFSYR 1885 >gi|18860892 protein tyrosine phosphatase, receptor type, D isoform 3 precursor [Homo sapiens] Length = 1903 Score = 225 bits (574), Expect = 4e-59 Identities = 130/355 (36%), Positives = 203/355 (57%), Gaps = 26/355 (7%) Query: 10 VVISVLAILSTLLIGLLLVTLIILRKKHLQMARECGAGTFVNFASLERDGKLPYNWSKNG 69 VV VLA++ +I +++ L+ RK+ +R+ +S+ + ++P + + Sbjct: 1261 VVGPVLAVV--FIICIVIAILLYKRKRAESDSRK---------SSIPNNKEIPSHHPTDP 1309 Query: 70 LKKRKLT---------NPVQLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADL 120 ++ R+L P+ + + +I+ + + + KFS ++E + G ++L Sbjct: 1310 VELRRLNFQTPGMASHPPIPILELADHIERLKANDNLKFSQEYESIDP-GQQFTWEHSNL 1368 Query: 121 PLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRN 180 +N+ KNRY N++ YD SRV L ++ G+DY+NANYI GY YIATQG LPET Sbjct: 1369 EVNKPKNRYANVIAYDHSRVLLSAIEGIPGSDYVNANYIDGYRKQNAYIATQGSLPETFG 1428 Query: 181 DFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDDWACR 240 DFW+M+ +Q+S +VM+T+ E+ RVKCD YWP + +G + V ++ E + R Sbjct: 1429 DFWRMIWEQRSATVVMMTKLEERSRVKCDQYWP-SRGTETHGLVQVTLLDTVELATYCVR 1487 Query: 241 HFRI--NYADEMQDVMHFNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCS 298 F + N + E ++V F +TAWPDHGVP L F+ V+ GPM++HCS Sbjct: 1488 TFALYKNGSSEKREVRQFQFTAWPDHGVP--EHPTPFLAFLRRVKTCNPPDAGPMVVHCS 1545 Query: 299 AGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCV 353 AGVGRTG FI +D +L+ I+ + VDI G V+ MR+ R MVQTE+QYIFIH + Sbjct: 1546 AGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRAQRNYMVQTEDQYIFIHDAL 1600 Score = 191 bits (484), Expect = 1e-48 Identities = 103/240 (42%), Positives = 144/240 (60%), Gaps = 9/240 (3%) Query: 117 AADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLP 176 +A+LP N+ KNR NI+PY+ +RV L + EG+DYINA++I GY + YIATQGPL Sbjct: 1654 SANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLA 1713 Query: 177 ETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDD 236 ET DFW+M+ + S I+VMLT+ E R KC YWP E Y V+ ++E Sbjct: 1714 ETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWP-AERSARYQYFVVDPMAEYNMPQ 1772 Query: 237 WACRHFRINYADEMQD--VMHFNYTAWPDHGVPTANAAESILQF---VHMVRQQATKSKG 291 + R F++ A + Q V F +T WP+ GVP + E + F VH ++Q + G Sbjct: 1773 YILREFKVTDARDGQSRTVRQFQFTDWPEQGVP--KSGEGFIDFIGQVHKTKEQFGQD-G 1829 Query: 292 PMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQ 351 P+ +HCSAGVGRTG FI L +L+ +R VDI V +R+ R +MVQTE+QY F ++ Sbjct: 1830 PISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDQYQFSYR 1889 >gi|18860894 protein tyrosine phosphatase, receptor type, D isoform 4 precursor [Homo sapiens] Length = 1501 Score = 225 bits (574), Expect = 4e-59 Identities = 130/355 (36%), Positives = 203/355 (57%), Gaps = 26/355 (7%) Query: 10 VVISVLAILSTLLIGLLLVTLIILRKKHLQMARECGAGTFVNFASLERDGKLPYNWSKNG 69 VV VLA++ +I +++ L+ RK+ +R+ +S+ + ++P + + Sbjct: 859 VVGPVLAVV--FIICIVIAILLYKRKRAESDSRK---------SSIPNNKEIPSHHPTDP 907 Query: 70 LKKRKLT---------NPVQLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADL 120 ++ R+L P+ + + +I+ + + + KFS ++E + G ++L Sbjct: 908 VELRRLNFQTPGMASHPPIPILELADHIERLKANDNLKFSQEYESIDP-GQQFTWEHSNL 966 Query: 121 PLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRN 180 +N+ KNRY N++ YD SRV L ++ G+DY+NANYI GY YIATQG LPET Sbjct: 967 EVNKPKNRYANVIAYDHSRVLLSAIEGIPGSDYVNANYIDGYRKQNAYIATQGSLPETFG 1026 Query: 181 DFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDDWACR 240 DFW+M+ +Q+S +VM+T+ E+ RVKCD YWP + +G + V ++ E + R Sbjct: 1027 DFWRMIWEQRSATVVMMTKLEERSRVKCDQYWP-SRGTETHGLVQVTLLDTVELATYCVR 1085 Query: 241 HFRI--NYADEMQDVMHFNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCS 298 F + N + E ++V F +TAWPDHGVP L F+ V+ GPM++HCS Sbjct: 1086 TFALYKNGSSEKREVRQFQFTAWPDHGVP--EHPTPFLAFLRRVKTCNPPDAGPMVVHCS 1143 Query: 299 AGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCV 353 AGVGRTG FI +D +L+ I+ + VDI G V+ MR+ R MVQTE+QYIFIH + Sbjct: 1144 AGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRAQRNYMVQTEDQYIFIHDAL 1198 Score = 191 bits (484), Expect = 1e-48 Identities = 103/240 (42%), Positives = 144/240 (60%), Gaps = 9/240 (3%) Query: 117 AADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLP 176 +A+LP N+ KNR NI+PY+ +RV L + EG+DYINA++I GY + YIATQGPL Sbjct: 1252 SANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLA 1311 Query: 177 ETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDD 236 ET DFW+M+ + S I+VMLT+ E R KC YWP E Y V+ ++E Sbjct: 1312 ETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWP-AERSARYQYFVVDPMAEYNMPQ 1370 Query: 237 WACRHFRINYADEMQD--VMHFNYTAWPDHGVPTANAAESILQF---VHMVRQQATKSKG 291 + R F++ A + Q V F +T WP+ GVP + E + F VH ++Q + G Sbjct: 1371 YILREFKVTDARDGQSRTVRQFQFTDWPEQGVP--KSGEGFIDFIGQVHKTKEQFGQD-G 1427 Query: 292 PMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQ 351 P+ +HCSAGVGRTG FI L +L+ +R VDI V +R+ R +MVQTE+QY F ++ Sbjct: 1428 PISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDQYQFSYR 1487 >gi|104487002 protein tyrosine phosphatase, receptor type, D isoform 5 precursor [Homo sapiens] Length = 1502 Score = 224 bits (571), Expect = 1e-58 Identities = 124/348 (35%), Positives = 199/348 (57%), Gaps = 19/348 (5%) Query: 17 ILSTLLIGLLLVTLIILRKKHLQMARECGAGTFVNFASLERDGKLPYNWSKNGLKKRKLT 76 +L+ + I +++ +++ + K + E + +S+ + ++P + + ++ R+L Sbjct: 860 VLAVVFIICIVIAILLYKSKPDRKRAESDSRK----SSIPNNKEIPSHHPTDPVELRRLN 915 Query: 77 ---------NPVQLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKN 127 P+ + + +I+ + + + KFS ++E + G ++L +N+ KN Sbjct: 916 FQTPGMASHPPIPILELADHIERLKANDNLKFSQEYESIDP-GQQFTWEHSNLEVNKPKN 974 Query: 128 RYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVL 187 RY N++ YD SRV L ++ G+DY+NANYI GY YIATQG LPET DFW+M+ Sbjct: 975 RYANVIAYDHSRVLLSAIEGIPGSDYVNANYIDGYRKQNAYIATQGSLPETFGDFWRMIW 1034 Query: 188 QQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDDWACRHFRI--N 245 +Q+S +VM+T+ E+ RVKCD YWP + +G + V ++ E + R F + N Sbjct: 1035 EQRSATVVMMTKLEERSRVKCDQYWP-SRGTETHGLVQVTLLDTVELATYCVRTFALYKN 1093 Query: 246 YADEMQDVMHFNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSAGVGRTG 305 + E ++V F +TAWPDHGVP L F+ V+ GPM++HCSAGVGRTG Sbjct: 1094 GSSEKREVRQFQFTAWPDHGVP--EHPTPFLAFLRRVKTCNPPDAGPMVVHCSAGVGRTG 1151 Query: 306 TFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCV 353 FI +D +L+ I+ + VDI G V+ MR+ R MVQTE+QYIFIH + Sbjct: 1152 CFIVIDAMLERIKHEKTVDIYGHVTLMRAQRNYMVQTEDQYIFIHDAL 1199 Score = 191 bits (484), Expect = 1e-48 Identities = 103/240 (42%), Positives = 144/240 (60%), Gaps = 9/240 (3%) Query: 117 AADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLP 176 +A+LP N+ KNR NI+PY+ +RV L + EG+DYINA++I GY + YIATQGPL Sbjct: 1253 SANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLA 1312 Query: 177 ETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDD 236 ET DFW+M+ + S I+VMLT+ E R KC YWP E Y V+ ++E Sbjct: 1313 ETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWP-AERSARYQYFVVDPMAEYNMPQ 1371 Query: 237 WACRHFRINYADEMQD--VMHFNYTAWPDHGVPTANAAESILQF---VHMVRQQATKSKG 291 + R F++ A + Q V F +T WP+ GVP + E + F VH ++Q + G Sbjct: 1372 YILREFKVTDARDGQSRTVRQFQFTDWPEQGVP--KSGEGFIDFIGQVHKTKEQFGQD-G 1428 Query: 292 PMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQ 351 P+ +HCSAGVGRTG FI L +L+ +R VDI V +R+ R +MVQTE+QY F ++ Sbjct: 1429 PISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDQYQFSYR 1488 >gi|104487611 protein tyrosine phosphatase, receptor type, sigma isoform 4 precursor [Homo sapiens] Length = 1505 Score = 223 bits (569), Expect = 2e-58 Identities = 118/278 (42%), Positives = 165/278 (59%), Gaps = 6/278 (2%) Query: 78 PVQLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDF 137 P+ + D + + + + K S ++E + G ++L +N+ KNRY N++ YD Sbjct: 929 PIPIADMAEHTERLKANDSLKLSQEYESIDP-GQQFTWEHSNLEVNKPKNRYANVIAYDH 987 Query: 138 SRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVML 197 SRV L + G+DYINANY+ GY YIATQGPLPET DFW+MV +Q+S IVM+ Sbjct: 988 SRVILQPIEGIMGSDYINANYVDGYRCQNAYIATQGPLPETFGDFWRMVWEQRSATIVMM 1047 Query: 198 TQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDDWACRHFRI--NYADEMQDVMH 255 T+ EK R+KCD YWP YG I V ++ E + R F + N + E ++V Sbjct: 1048 TRLEEKSRIKCDQYWP-NRGTETYGFIQVTLLDTIELATFCVRTFSLHKNGSSEKREVRQ 1106 Query: 256 FNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQ 315 F +TAWPDHGVP L F+ V+ GP+++HCSAGVGRTG FI +D +L+ Sbjct: 1107 FQFTAWPDHGVP--EYPTPFLAFLRRVKTCNPPDAGPIVVHCSAGVGRTGCFIVIDAMLE 1164 Query: 316 HIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCV 353 I+ + VD+ G V+ MRS R MVQTE+QY FIH+ + Sbjct: 1165 RIKPEKTVDVYGHVTLMRSQRNYMVQTEDQYSFIHEAL 1202 Score = 191 bits (486), Expect = 7e-49 Identities = 103/240 (42%), Positives = 144/240 (60%), Gaps = 9/240 (3%) Query: 117 AADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLP 176 +A+LP N+ KNR NI+PY+ +RV L + EG+DYINA++I GY + YIATQGPL Sbjct: 1256 SANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLA 1315 Query: 177 ETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDD 236 ET DFW+M+ + S I+VMLT+ E R KC YWP E Y V+ ++E Sbjct: 1316 ETTEDFWRMLWENNSTIVVMLTKLREMGREKCHQYWP-AERSARYQYFVVDPMAEYNMPQ 1374 Query: 237 WACRHFRINYADEMQD--VMHFNYTAWPDHGVPTANAAESILQF---VHMVRQQATKSKG 291 + R F++ A + Q V F +T WP+ GVP + E + F VH ++Q + G Sbjct: 1375 YILREFKVTDARDGQSRTVRQFQFTDWPEQGVP--KSGEGFIDFIGQVHKTKEQFGQD-G 1431 Query: 292 PMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQ 351 P+ +HCSAGVGRTG FI L +L+ +R VDI V +R+ R +MVQTE++Y F +Q Sbjct: 1432 PISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDEYQFCYQ 1491 >gi|104487297 protein tyrosine phosphatase, receptor type, sigma isoform 2 precursor [Homo sapiens] Length = 1910 Score = 223 bits (569), Expect = 2e-58 Identities = 118/278 (42%), Positives = 165/278 (59%), Gaps = 6/278 (2%) Query: 78 PVQLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDF 137 P+ + D + + + + K S ++E + G ++L +N+ KNRY N++ YD Sbjct: 1334 PIPIADMAEHTERLKANDSLKLSQEYESIDP-GQQFTWEHSNLEVNKPKNRYANVIAYDH 1392 Query: 138 SRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVML 197 SRV L + G+DYINANY+ GY YIATQGPLPET DFW+MV +Q+S IVM+ Sbjct: 1393 SRVILQPIEGIMGSDYINANYVDGYRCQNAYIATQGPLPETFGDFWRMVWEQRSATIVMM 1452 Query: 198 TQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDDWACRHFRI--NYADEMQDVMH 255 T+ EK R+KCD YWP YG I V ++ E + R F + N + E ++V Sbjct: 1453 TRLEEKSRIKCDQYWP-NRGTETYGFIQVTLLDTIELATFCVRTFSLHKNGSSEKREVRQ 1511 Query: 256 FNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQ 315 F +TAWPDHGVP L F+ V+ GP+++HCSAGVGRTG FI +D +L+ Sbjct: 1512 FQFTAWPDHGVP--EYPTPFLAFLRRVKTCNPPDAGPIVVHCSAGVGRTGCFIVIDAMLE 1569 Query: 316 HIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCV 353 I+ + VD+ G V+ MRS R MVQTE+QY FIH+ + Sbjct: 1570 RIKPEKTVDVYGHVTLMRSQRNYMVQTEDQYSFIHEAL 1607 Score = 191 bits (486), Expect = 7e-49 Identities = 103/240 (42%), Positives = 144/240 (60%), Gaps = 9/240 (3%) Query: 117 AADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLP 176 +A+LP N+ KNR NI+PY+ +RV L + EG+DYINA++I GY + YIATQGPL Sbjct: 1661 SANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLA 1720 Query: 177 ETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDD 236 ET DFW+M+ + S I+VMLT+ E R KC YWP E Y V+ ++E Sbjct: 1721 ETTEDFWRMLWENNSTIVVMLTKLREMGREKCHQYWP-AERSARYQYFVVDPMAEYNMPQ 1779 Query: 237 WACRHFRINYADEMQD--VMHFNYTAWPDHGVPTANAAESILQF---VHMVRQQATKSKG 291 + R F++ A + Q V F +T WP+ GVP + E + F VH ++Q + G Sbjct: 1780 YILREFKVTDARDGQSRTVRQFQFTDWPEQGVP--KSGEGFIDFIGQVHKTKEQFGQD-G 1836 Query: 292 PMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQ 351 P+ +HCSAGVGRTG FI L +L+ +R VDI V +R+ R +MVQTE++Y F +Q Sbjct: 1837 PISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDEYQFCYQ 1896 >gi|104487295 protein tyrosine phosphatase, receptor type, sigma isoform 3 precursor [Homo sapiens] Length = 1501 Score = 223 bits (569), Expect = 2e-58 Identities = 118/278 (42%), Positives = 165/278 (59%), Gaps = 6/278 (2%) Query: 78 PVQLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDF 137 P+ + D + + + + K S ++E + G ++L +N+ KNRY N++ YD Sbjct: 925 PIPIADMAEHTERLKANDSLKLSQEYESIDP-GQQFTWEHSNLEVNKPKNRYANVIAYDH 983 Query: 138 SRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVML 197 SRV L + G+DYINANY+ GY YIATQGPLPET DFW+MV +Q+S IVM+ Sbjct: 984 SRVILQPIEGIMGSDYINANYVDGYRCQNAYIATQGPLPETFGDFWRMVWEQRSATIVMM 1043 Query: 198 TQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDDWACRHFRI--NYADEMQDVMH 255 T+ EK R+KCD YWP YG I V ++ E + R F + N + E ++V Sbjct: 1044 TRLEEKSRIKCDQYWP-NRGTETYGFIQVTLLDTIELATFCVRTFSLHKNGSSEKREVRQ 1102 Query: 256 FNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQ 315 F +TAWPDHGVP L F+ V+ GP+++HCSAGVGRTG FI +D +L+ Sbjct: 1103 FQFTAWPDHGVP--EYPTPFLAFLRRVKTCNPPDAGPIVVHCSAGVGRTGCFIVIDAMLE 1160 Query: 316 HIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCV 353 I+ + VD+ G V+ MRS R MVQTE+QY FIH+ + Sbjct: 1161 RIKPEKTVDVYGHVTLMRSQRNYMVQTEDQYSFIHEAL 1198 Score = 191 bits (486), Expect = 7e-49 Identities = 103/240 (42%), Positives = 144/240 (60%), Gaps = 9/240 (3%) Query: 117 AADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLP 176 +A+LP N+ KNR NI+PY+ +RV L + EG+DYINA++I GY + YIATQGPL Sbjct: 1252 SANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLA 1311 Query: 177 ETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDD 236 ET DFW+M+ + S I+VMLT+ E R KC YWP E Y V+ ++E Sbjct: 1312 ETTEDFWRMLWENNSTIVVMLTKLREMGREKCHQYWP-AERSARYQYFVVDPMAEYNMPQ 1370 Query: 237 WACRHFRINYADEMQD--VMHFNYTAWPDHGVPTANAAESILQF---VHMVRQQATKSKG 291 + R F++ A + Q V F +T WP+ GVP + E + F VH ++Q + G Sbjct: 1371 YILREFKVTDARDGQSRTVRQFQFTDWPEQGVP--KSGEGFIDFIGQVHKTKEQFGQD-G 1427 Query: 292 PMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQ 351 P+ +HCSAGVGRTG FI L +L+ +R VDI V +R+ R +MVQTE++Y F +Q Sbjct: 1428 PISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDEYQFCYQ 1487 >gi|104487006 protein tyrosine phosphatase, receptor type, sigma isoform 1 precursor [Homo sapiens] Length = 1948 Score = 223 bits (569), Expect = 2e-58 Identities = 118/278 (42%), Positives = 165/278 (59%), Gaps = 6/278 (2%) Query: 78 PVQLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDF 137 P+ + D + + + + K S ++E + G ++L +N+ KNRY N++ YD Sbjct: 1372 PIPIADMAEHTERLKANDSLKLSQEYESIDP-GQQFTWEHSNLEVNKPKNRYANVIAYDH 1430 Query: 138 SRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVML 197 SRV L + G+DYINANY+ GY YIATQGPLPET DFW+MV +Q+S IVM+ Sbjct: 1431 SRVILQPIEGIMGSDYINANYVDGYRCQNAYIATQGPLPETFGDFWRMVWEQRSATIVMM 1490 Query: 198 TQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDDWACRHFRI--NYADEMQDVMH 255 T+ EK R+KCD YWP YG I V ++ E + R F + N + E ++V Sbjct: 1491 TRLEEKSRIKCDQYWP-NRGTETYGFIQVTLLDTIELATFCVRTFSLHKNGSSEKREVRQ 1549 Query: 256 FNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQ 315 F +TAWPDHGVP L F+ V+ GP+++HCSAGVGRTG FI +D +L+ Sbjct: 1550 FQFTAWPDHGVP--EYPTPFLAFLRRVKTCNPPDAGPIVVHCSAGVGRTGCFIVIDAMLE 1607 Query: 316 HIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCV 353 I+ + VD+ G V+ MRS R MVQTE+QY FIH+ + Sbjct: 1608 RIKPEKTVDVYGHVTLMRSQRNYMVQTEDQYSFIHEAL 1645 Score = 191 bits (486), Expect = 7e-49 Identities = 103/240 (42%), Positives = 144/240 (60%), Gaps = 9/240 (3%) Query: 117 AADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLP 176 +A+LP N+ KNR NI+PY+ +RV L + EG+DYINA++I GY + YIATQGPL Sbjct: 1699 SANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLA 1758 Query: 177 ETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDD 236 ET DFW+M+ + S I+VMLT+ E R KC YWP E Y V+ ++E Sbjct: 1759 ETTEDFWRMLWENNSTIVVMLTKLREMGREKCHQYWP-AERSARYQYFVVDPMAEYNMPQ 1817 Query: 237 WACRHFRINYADEMQD--VMHFNYTAWPDHGVPTANAAESILQF---VHMVRQQATKSKG 291 + R F++ A + Q V F +T WP+ GVP + E + F VH ++Q + G Sbjct: 1818 YILREFKVTDARDGQSRTVRQFQFTDWPEQGVP--KSGEGFIDFIGQVHKTKEQFGQD-G 1874 Query: 292 PMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQ 351 P+ +HCSAGVGRTG FI L +L+ +R VDI V +R+ R +MVQTE++Y F +Q Sbjct: 1875 PISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDEYQFCYQ 1934 >gi|148539860 protein tyrosine phosphatase, receptor type, T isoform 2 precursor [Homo sapiens] Length = 1441 Score = 222 bits (566), Expect = 4e-58 Identities = 118/277 (42%), Positives = 167/277 (60%), Gaps = 7/277 (2%) Query: 79 VQLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDFS 138 +++ D +I M + Y F ++E L G A NR KNRY NI+ YD S Sbjct: 869 IRVADLLQHITQMKRGQGYGFKEEYEALPE-GQTASWDTAKEDENRNKNRYGNIISYDHS 927 Query: 139 RVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLT 198 RVRL+ ++ + +DYINANYI GY+ P+ YIATQGP+ ET DFW+M+ Q+ S IVM+T Sbjct: 928 RVRLLVLDGDPHSDYINANYIDGYHRPRHYIATQGPMQETVKDFWRMIWQENSASIVMVT 987 Query: 199 QCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDDWACRHFRINYA--DEMQDVMHF 256 E RVKC YWP ++ YGDI V +I E ++ R F + E++++ F Sbjct: 988 NLVEVGRVKCVRYWP--DDTEVYGDIKVTLIETEPLAEYVIRTFTVQKKGYHEIRELRLF 1045 Query: 257 NYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQH 316 ++T+WPDHGVP A +L FV V+ GP+++HCSAG GRTG FIA+D +L Sbjct: 1046 HFTSWPDHGVPC--YATGLLGFVRQVKFLNPPEAGPIVVHCSAGAGRTGCFIAIDTMLDM 1103 Query: 317 IRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCV 353 + VDI V E+R+ R+++VQTEEQY+F+H + Sbjct: 1104 AENEGVVDIFNCVRELRAQRVNLVQTEEQYVFVHDAI 1140 Score = 128 bits (321), Expect = 1e-29 Identities = 78/239 (32%), Positives = 125/239 (52%), Gaps = 12/239 (5%) Query: 120 LPLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETR 179 LP N KNR ++LP D L+S+ + E ++YINA + + P ++ TQ PLP T Sbjct: 1199 LPRNHDKNRSMDVLPLDRCLPFLISV-DGESSNYINAALMDSHKQPAAFVVTQHPLPNTV 1257 Query: 180 NDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDDWAC 239 DFW++V +VML + + + C YWP + YG I VE +S + +D Sbjct: 1258 ADFWRLVFDYNCSSVVMLNEMDTAQF--CMQYWP-EKTSGCYGPIQVEFVSADIDEDIIH 1314 Query: 240 RHFRINYADEMQD----VMHFNYTAWPDHGVPTANAAESILQFVHMV---RQQATKSKGP 292 R FRI QD V H Y WP + T + S+L+ V + ++Q +G Sbjct: 1315 RIFRICNMARPQDGYRIVQHLQYIGWPAYR-DTPPSKRSLLKVVRRLEKWQEQYDGREGR 1373 Query: 293 MIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQ 351 ++HC G GR+GTF A+ + + I+ +D+ +V +R+ + +MV+T EQY F+++ Sbjct: 1374 TVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFHIVKTLRNNKSNMVETLEQYKFVYE 1432 >gi|148539858 protein tyrosine phosphatase, receptor type, T isoform 1 precursor [Homo sapiens] Length = 1460 Score = 222 bits (566), Expect = 4e-58 Identities = 118/277 (42%), Positives = 167/277 (60%), Gaps = 7/277 (2%) Query: 79 VQLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDFS 138 +++ D +I M + Y F ++E L G A NR KNRY NI+ YD S Sbjct: 888 IRVADLLQHITQMKRGQGYGFKEEYEALPE-GQTASWDTAKEDENRNKNRYGNIISYDHS 946 Query: 139 RVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLT 198 RVRL+ ++ + +DYINANYI GY+ P+ YIATQGP+ ET DFW+M+ Q+ S IVM+T Sbjct: 947 RVRLLVLDGDPHSDYINANYIDGYHRPRHYIATQGPMQETVKDFWRMIWQENSASIVMVT 1006 Query: 199 QCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDDWACRHFRINYA--DEMQDVMHF 256 E RVKC YWP ++ YGDI V +I E ++ R F + E++++ F Sbjct: 1007 NLVEVGRVKCVRYWP--DDTEVYGDIKVTLIETEPLAEYVIRTFTVQKKGYHEIRELRLF 1064 Query: 257 NYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQH 316 ++T+WPDHGVP A +L FV V+ GP+++HCSAG GRTG FIA+D +L Sbjct: 1065 HFTSWPDHGVPC--YATGLLGFVRQVKFLNPPEAGPIVVHCSAGAGRTGCFIAIDTMLDM 1122 Query: 317 IRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCV 353 + VDI V E+R+ R+++VQTEEQY+F+H + Sbjct: 1123 AENEGVVDIFNCVRELRAQRVNLVQTEEQYVFVHDAI 1159 Score = 128 bits (321), Expect = 1e-29 Identities = 78/239 (32%), Positives = 125/239 (52%), Gaps = 12/239 (5%) Query: 120 LPLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETR 179 LP N KNR ++LP D L+S+ + E ++YINA + + P ++ TQ PLP T Sbjct: 1218 LPRNHDKNRSMDVLPLDRCLPFLISV-DGESSNYINAALMDSHKQPAAFVVTQHPLPNTV 1276 Query: 180 NDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDDWAC 239 DFW++V +VML + + + C YWP + YG I VE +S + +D Sbjct: 1277 ADFWRLVFDYNCSSVVMLNEMDTAQF--CMQYWP-EKTSGCYGPIQVEFVSADIDEDIIH 1333 Query: 240 RHFRINYADEMQD----VMHFNYTAWPDHGVPTANAAESILQFVHMV---RQQATKSKGP 292 R FRI QD V H Y WP + T + S+L+ V + ++Q +G Sbjct: 1334 RIFRICNMARPQDGYRIVQHLQYIGWPAYR-DTPPSKRSLLKVVRRLEKWQEQYDGREGR 1392 Query: 293 MIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQ 351 ++HC G GR+GTF A+ + + I+ +D+ +V +R+ + +MV+T EQY F+++ Sbjct: 1393 TVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFHIVKTLRNNKSNMVETLEQYKFVYE 1451 >gi|18641364 protein tyrosine phosphatase, receptor type, C isoform 3 precursor [Homo sapiens] Length = 1256 Score = 220 bits (560), Expect = 2e-57 Identities = 125/346 (36%), Positives = 188/346 (54%), Gaps = 19/346 (5%) Query: 13 SVLAILSTLLIGLLLVTLIILRKKH-LQMARECGAGTFVNFASLERDGKLPYNWSKNGLK 71 +++A L+ L+I + L++L K + L R C +ERD + K Sbjct: 528 ALIAFLAFLIIVTSIALLVVLYKIYDLHKKRSCNLDEQQEL--VERDDE----------K 575 Query: 72 KRKLTNPVQLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTN 131 + P+ D K D F +F+ + + P A P N+ KNRY + Sbjct: 576 QLMNVEPIHADILLETYKRKIADEGRLFLAEFQSIPRVFSKFPIKEARKPFNQNKNRYVD 635 Query: 132 ILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKS 191 ILPYD++RV L +N + G++YINA+YI G+ P++YIA QGP ET +DFW+M+ +QK+ Sbjct: 636 ILPYDYNRVELSEINGDAGSNYINASYIDGFKEPRKYIAAQGPRDETVDDFWRMIWEQKA 695 Query: 192 QIIVMLTQCNEKRRVKCDHYWPFTEEPI-AYGDITVEMISEEEQDDWACRHFRINYADEM 250 +IVM+T+C E R KC YWP EE A+GD+ V++ + D+ + I E Sbjct: 696 TVIVMVTRCEEGNRNKCAEYWPSMEEGTRAFGDVVVKINQHKRCPDYIIQKLNIVNKKEK 755 Query: 251 ---QDVMHFNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTF 307 ++V H +T+WPDHGVP +L+ V + GP+++HCSAGVGRTGT+ Sbjct: 756 ATGREVTHIQFTSWPDHGVP--EDPHLLLKLRRRVNAFSNFFSGPIVVHCSAGVGRTGTY 813 Query: 308 IALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCV 353 I +D +L+ + VD+ G V ++R R MVQ E QYI IHQ + Sbjct: 814 IGIDAMLEGLEAENKVDVYGYVVKLRRQRCLMVQVEAQYILIHQAL 859 Score = 140 bits (354), Expect = 1e-33 Identities = 87/260 (33%), Positives = 129/260 (49%), Gaps = 31/260 (11%) Query: 123 NRCKNRYTNILPYDFSRVRLV-------------------SMNEEEGADYINANYIPGYN 163 N+ KNR +N++PYD++RV L + EE + YINA++I Y Sbjct: 918 NKSKNRNSNVIPYDYNRVPLKHELEMSKESEHDSDESSDDDSDSEEPSKYINASFIMSYW 977 Query: 164 SPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGD 223 P+ IA QGPL ET DFW+M+ Q+K ++IVMLT+ + C YW E YGD Sbjct: 978 KPEVMIAAQGPLKETIGDFWQMIFQRKVKVIVMLTELKHGDQEICAQYW--GEGKQTYGD 1035 Query: 224 ITVEMISEEEQDDWACRHFRINYA--DEMQDVMHFNYTAWPDHGVPT-ANAAESILQFVH 280 I V++ ++ + R F + ++ + + V + YT W +P S++Q V Sbjct: 1036 IEVDLKDTDKSSTYTLRVFELRHSKRKDSRTVYQYQYTNWSVEQLPAEPKELISMIQVVK 1095 Query: 281 MVRQQATKSKG-------PMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMR 333 Q S+G P++IHC G +TG F AL LL+ E VDI +V +R Sbjct: 1096 QKLPQKNSSEGNKHHKSTPLLIHCRDGSQQTGIFCALLNLLESAETEEVVDIFQVVKALR 1155 Query: 334 SYRMSMVQTEEQYIFIHQCV 353 R MV T EQY F++ + Sbjct: 1156 KARPGMVSTFEQYQFLYDVI 1175 >gi|18641347 protein tyrosine phosphatase, receptor type, C isoform 1 precursor [Homo sapiens] Length = 1304 Score = 220 bits (560), Expect = 2e-57 Identities = 125/346 (36%), Positives = 188/346 (54%), Gaps = 19/346 (5%) Query: 13 SVLAILSTLLIGLLLVTLIILRKKH-LQMARECGAGTFVNFASLERDGKLPYNWSKNGLK 71 +++A L+ L+I + L++L K + L R C +ERD + K Sbjct: 576 ALIAFLAFLIIVTSIALLVVLYKIYDLHKKRSCNLDEQQEL--VERDDE----------K 623 Query: 72 KRKLTNPVQLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTN 131 + P+ D K D F +F+ + + P A P N+ KNRY + Sbjct: 624 QLMNVEPIHADILLETYKRKIADEGRLFLAEFQSIPRVFSKFPIKEARKPFNQNKNRYVD 683 Query: 132 ILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKS 191 ILPYD++RV L +N + G++YINA+YI G+ P++YIA QGP ET +DFW+M+ +QK+ Sbjct: 684 ILPYDYNRVELSEINGDAGSNYINASYIDGFKEPRKYIAAQGPRDETVDDFWRMIWEQKA 743 Query: 192 QIIVMLTQCNEKRRVKCDHYWPFTEEPI-AYGDITVEMISEEEQDDWACRHFRINYADEM 250 +IVM+T+C E R KC YWP EE A+GD+ V++ + D+ + I E Sbjct: 744 TVIVMVTRCEEGNRNKCAEYWPSMEEGTRAFGDVVVKINQHKRCPDYIIQKLNIVNKKEK 803 Query: 251 ---QDVMHFNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTF 307 ++V H +T+WPDHGVP +L+ V + GP+++HCSAGVGRTGT+ Sbjct: 804 ATGREVTHIQFTSWPDHGVP--EDPHLLLKLRRRVNAFSNFFSGPIVVHCSAGVGRTGTY 861 Query: 308 IALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCV 353 I +D +L+ + VD+ G V ++R R MVQ E QYI IHQ + Sbjct: 862 IGIDAMLEGLEAENKVDVYGYVVKLRRQRCLMVQVEAQYILIHQAL 907 Score = 140 bits (354), Expect = 1e-33 Identities = 87/260 (33%), Positives = 129/260 (49%), Gaps = 31/260 (11%) Query: 123 NRCKNRYTNILPYDFSRVRLV-------------------SMNEEEGADYINANYIPGYN 163 N+ KNR +N++PYD++RV L + EE + YINA++I Y Sbjct: 966 NKSKNRNSNVIPYDYNRVPLKHELEMSKESEHDSDESSDDDSDSEEPSKYINASFIMSYW 1025 Query: 164 SPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGD 223 P+ IA QGPL ET DFW+M+ Q+K ++IVMLT+ + C YW E YGD Sbjct: 1026 KPEVMIAAQGPLKETIGDFWQMIFQRKVKVIVMLTELKHGDQEICAQYW--GEGKQTYGD 1083 Query: 224 ITVEMISEEEQDDWACRHFRINYA--DEMQDVMHFNYTAWPDHGVPT-ANAAESILQFVH 280 I V++ ++ + R F + ++ + + V + YT W +P S++Q V Sbjct: 1084 IEVDLKDTDKSSTYTLRVFELRHSKRKDSRTVYQYQYTNWSVEQLPAEPKELISMIQVVK 1143 Query: 281 MVRQQATKSKG-------PMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMR 333 Q S+G P++IHC G +TG F AL LL+ E VDI +V +R Sbjct: 1144 QKLPQKNSSEGNKHHKSTPLLIHCRDGSQQTGIFCALLNLLESAETEEVVDIFQVVKALR 1203 Query: 334 SYRMSMVQTEEQYIFIHQCV 353 R MV T EQY F++ + Sbjct: 1204 KARPGMVSTFEQYQFLYDVI 1223 >gi|18641362 protein tyrosine phosphatase, receptor type, C isoform 2 precursor [Homo sapiens] Length = 1143 Score = 220 bits (560), Expect = 2e-57 Identities = 125/346 (36%), Positives = 188/346 (54%), Gaps = 19/346 (5%) Query: 13 SVLAILSTLLIGLLLVTLIILRKKH-LQMARECGAGTFVNFASLERDGKLPYNWSKNGLK 71 +++A L+ L+I + L++L K + L R C +ERD + K Sbjct: 415 ALIAFLAFLIIVTSIALLVVLYKIYDLHKKRSCNLDEQQEL--VERDDE----------K 462 Query: 72 KRKLTNPVQLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTN 131 + P+ D K D F +F+ + + P A P N+ KNRY + Sbjct: 463 QLMNVEPIHADILLETYKRKIADEGRLFLAEFQSIPRVFSKFPIKEARKPFNQNKNRYVD 522 Query: 132 ILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKS 191 ILPYD++RV L +N + G++YINA+YI G+ P++YIA QGP ET +DFW+M+ +QK+ Sbjct: 523 ILPYDYNRVELSEINGDAGSNYINASYIDGFKEPRKYIAAQGPRDETVDDFWRMIWEQKA 582 Query: 192 QIIVMLTQCNEKRRVKCDHYWPFTEEPI-AYGDITVEMISEEEQDDWACRHFRINYADEM 250 +IVM+T+C E R KC YWP EE A+GD+ V++ + D+ + I E Sbjct: 583 TVIVMVTRCEEGNRNKCAEYWPSMEEGTRAFGDVVVKINQHKRCPDYIIQKLNIVNKKEK 642 Query: 251 ---QDVMHFNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTF 307 ++V H +T+WPDHGVP +L+ V + GP+++HCSAGVGRTGT+ Sbjct: 643 ATGREVTHIQFTSWPDHGVP--EDPHLLLKLRRRVNAFSNFFSGPIVVHCSAGVGRTGTY 700 Query: 308 IALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCV 353 I +D +L+ + VD+ G V ++R R MVQ E QYI IHQ + Sbjct: 701 IGIDAMLEGLEAENKVDVYGYVVKLRRQRCLMVQVEAQYILIHQAL 746 Score = 140 bits (354), Expect = 1e-33 Identities = 87/260 (33%), Positives = 129/260 (49%), Gaps = 31/260 (11%) Query: 123 NRCKNRYTNILPYDFSRVRLV-------------------SMNEEEGADYINANYIPGYN 163 N+ KNR +N++PYD++RV L + EE + YINA++I Y Sbjct: 805 NKSKNRNSNVIPYDYNRVPLKHELEMSKESEHDSDESSDDDSDSEEPSKYINASFIMSYW 864 Query: 164 SPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGD 223 P+ IA QGPL ET DFW+M+ Q+K ++IVMLT+ + C YW E YGD Sbjct: 865 KPEVMIAAQGPLKETIGDFWQMIFQRKVKVIVMLTELKHGDQEICAQYW--GEGKQTYGD 922 Query: 224 ITVEMISEEEQDDWACRHFRINYA--DEMQDVMHFNYTAWPDHGVPT-ANAAESILQFVH 280 I V++ ++ + R F + ++ + + V + YT W +P S++Q V Sbjct: 923 IEVDLKDTDKSSTYTLRVFELRHSKRKDSRTVYQYQYTNWSVEQLPAEPKELISMIQVVK 982 Query: 281 MVRQQATKSKG-------PMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMR 333 Q S+G P++IHC G +TG F AL LL+ E VDI +V +R Sbjct: 983 QKLPQKNSSEGNKHHKSTPLLIHCRDGSQQTGIFCALLNLLESAETEEVVDIFQVVKALR 1042 Query: 334 SYRMSMVQTEEQYIFIHQCV 353 R MV T EQY F++ + Sbjct: 1043 KARPGMVSTFEQYQFLYDVI 1062 >gi|157419150 protein tyrosine phosphatase, receptor type, M isoform 2 precursor [Homo sapiens] Length = 1452 Score = 219 bits (558), Expect = 3e-57 Identities = 117/277 (42%), Positives = 162/277 (58%), Gaps = 7/277 (2%) Query: 79 VQLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDFS 138 +++ D +I M Y F ++E G P +A NR KNRY NI+ YD S Sbjct: 880 IRVADLLQHITQMKCAEGYGFKEEYESF-FEGQSAPWDSAKKDENRMKNRYGNIIAYDHS 938 Query: 139 RVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLT 198 RVRL ++ + +DYIN NYI GY+ P YIATQGP+ ET DFW+MV + + I+M+T Sbjct: 939 RVRLQTIEGDTNSDYINGNYIDGYHRPNHYIATQGPMQETIYDFWRMVWHENTASIIMVT 998 Query: 199 QCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDDWACRHFRINY--ADEMQDVMHF 256 E RVKC YWP ++ Y DI V +I E ++ R F + E++++ F Sbjct: 999 NLVEVGRVKCCKYWP--DDTEIYKDIKVTLIETELLAEYVIRTFAVEKRGVHEIREIRQF 1056 Query: 257 NYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQH 316 ++T WPDHGVP A +L FV V+ ++ S GP+++HCSAG GRTG FI +D +L Sbjct: 1057 HFTGWPDHGVP--YHATGLLGFVRQVKSKSPPSAGPLVVHCSAGAGRTGCFIVIDIMLDM 1114 Query: 317 IRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCV 353 VDI V E+RS R++MVQTEEQY+FIH + Sbjct: 1115 AEREGVVDIYNCVRELRSRRVNMVQTEEQYVFIHDAI 1151 Score = 122 bits (306), Expect = 5e-28 Identities = 79/240 (32%), Positives = 123/240 (51%), Gaps = 14/240 (5%) Query: 120 LPLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETR 179 LP N KNR +ILP D L+++ + E ++YINA + Y P +I TQ PLP T Sbjct: 1210 LPRNHEKNRCMDILPPDRCLPFLITI-DGESSNYINAALMDSYKQPSAFIVTQHPLPNTV 1268 Query: 180 NDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPI-AYGDITVEMISEEEQDDWA 238 DFW++VL +VML + + C YWP E + +G I VE +S + ++D Sbjct: 1269 KDFWRLVLDYHCTSVVMLNDVDPAQ--LCPQYWP--ENGVHRHGPIQVEFVSADLEEDII 1324 Query: 239 CRHFRINYADEMQD----VMHFNYTAWPDHGVPTANAAESILQFVHMV---RQQATKSKG 291 R FRI A QD V F + WP + T + S L+ + V +++ +G Sbjct: 1325 SRIFRIYNAARPQDGYRMVQQFQFLGWPMYR-DTPVSKRSFLKLIRQVDKWQEEYNGGEG 1383 Query: 292 PMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQ 351 ++HC G GR+GTF A+ + + +R VD+ V +R+ + +MV +QY F ++ Sbjct: 1384 RTVVHCLNGGGRSGTFCAISIVCEMLRHQRTVDVFHAVKTLRNNKPNMVDLLDQYKFCYE 1443 >gi|157419152 protein tyrosine phosphatase, receptor type, M isoform 1 precursor [Homo sapiens] Length = 1465 Score = 219 bits (558), Expect = 3e-57 Identities = 117/277 (42%), Positives = 162/277 (58%), Gaps = 7/277 (2%) Query: 79 VQLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDFS 138 +++ D +I M Y F ++E G P +A NR KNRY NI+ YD S Sbjct: 893 IRVADLLQHITQMKCAEGYGFKEEYESF-FEGQSAPWDSAKKDENRMKNRYGNIIAYDHS 951 Query: 139 RVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLT 198 RVRL ++ + +DYIN NYI GY+ P YIATQGP+ ET DFW+MV + + I+M+T Sbjct: 952 RVRLQTIEGDTNSDYINGNYIDGYHRPNHYIATQGPMQETIYDFWRMVWHENTASIIMVT 1011 Query: 199 QCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDDWACRHFRINY--ADEMQDVMHF 256 E RVKC YWP ++ Y DI V +I E ++ R F + E++++ F Sbjct: 1012 NLVEVGRVKCCKYWP--DDTEIYKDIKVTLIETELLAEYVIRTFAVEKRGVHEIREIRQF 1069 Query: 257 NYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQH 316 ++T WPDHGVP A +L FV V+ ++ S GP+++HCSAG GRTG FI +D +L Sbjct: 1070 HFTGWPDHGVP--YHATGLLGFVRQVKSKSPPSAGPLVVHCSAGAGRTGCFIVIDIMLDM 1127 Query: 317 IRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCV 353 VDI V E+RS R++MVQTEEQY+FIH + Sbjct: 1128 AEREGVVDIYNCVRELRSRRVNMVQTEEQYVFIHDAI 1164 Score = 122 bits (306), Expect = 5e-28 Identities = 79/240 (32%), Positives = 123/240 (51%), Gaps = 14/240 (5%) Query: 120 LPLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETR 179 LP N KNR +ILP D L+++ + E ++YINA + Y P +I TQ PLP T Sbjct: 1223 LPRNHEKNRCMDILPPDRCLPFLITI-DGESSNYINAALMDSYKQPSAFIVTQHPLPNTV 1281 Query: 180 NDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPI-AYGDITVEMISEEEQDDWA 238 DFW++VL +VML + + C YWP E + +G I VE +S + ++D Sbjct: 1282 KDFWRLVLDYHCTSVVMLNDVDPAQ--LCPQYWP--ENGVHRHGPIQVEFVSADLEEDII 1337 Query: 239 CRHFRINYADEMQD----VMHFNYTAWPDHGVPTANAAESILQFVHMV---RQQATKSKG 291 R FRI A QD V F + WP + T + S L+ + V +++ +G Sbjct: 1338 SRIFRIYNAARPQDGYRMVQQFQFLGWPMYR-DTPVSKRSFLKLIRQVDKWQEEYNGGEG 1396 Query: 292 PMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQ 351 ++HC G GR+GTF A+ + + +R VD+ V +R+ + +MV +QY F ++ Sbjct: 1397 RTVVHCLNGGGRSGTFCAISIVCEMLRHQRTVDVFHAVKTLRNNKPNMVDLLDQYKFCYE 1456 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.323 0.137 0.416 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 13,694,082 Number of Sequences: 37866 Number of extensions: 582026 Number of successful extensions: 1800 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 113 Number of HSP's successfully gapped in prelim test: 14 Number of HSP's that attempted gapping in prelim test: 1309 Number of HSP's gapped (non-prelim): 172 length of query: 377 length of database: 18,247,518 effective HSP length: 104 effective length of query: 273 effective length of database: 14,309,454 effective search space: 3906480942 effective search space used: 3906480942 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (22.0 bits) S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.