Guide to the Human Genome
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Search of human proteins with 13677218

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|13677218 receptor-type protein tyrosine phosphatase O
isoform c precursor [Homo sapiens]
         (405 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|13677222 receptor-type protein tyrosine phosphatase O isoform...   833   0.0  
gi|13677218 receptor-type protein tyrosine phosphatase O isoform...   833   0.0  
gi|13677214 receptor-type protein tyrosine phosphatase O isoform...   833   0.0  
gi|13677220 receptor-type protein tyrosine phosphatase O isoform...   758   0.0  
gi|13677216 receptor-type protein tyrosine phosphatase O isoform...   758   0.0  
gi|4506323 receptor-type protein tyrosine phosphatase O isoform ...   758   0.0  
gi|157952215 protein tyrosine phosphatase, receptor type, B isof...   297   1e-80
gi|157952213 protein tyrosine phosphatase, receptor type, B isof...   297   1e-80
gi|222537743 protein tyrosine phosphatase, receptor type, Q [Hom...   283   3e-76
gi|148728162 protein tyrosine phosphatase, receptor type, J isof...   278   6e-75
gi|241896926 protein tyrosine phosphatase, receptor type, H isof...   268   5e-72
gi|241896924 protein tyrosine phosphatase, receptor type, H isof...   268   5e-72
gi|109633041 protein tyrosine phosphatase, receptor type, F isof...   225   5e-59
gi|109633039 protein tyrosine phosphatase, receptor type, F isof...   225   5e-59
gi|104487611 protein tyrosine phosphatase, receptor type, sigma ...   223   2e-58
gi|104487297 protein tyrosine phosphatase, receptor type, sigma ...   223   2e-58
gi|104487295 protein tyrosine phosphatase, receptor type, sigma ...   223   2e-58
gi|104487006 protein tyrosine phosphatase, receptor type, sigma ...   223   2e-58
gi|104487002 protein tyrosine phosphatase, receptor type, D isof...   223   2e-58
gi|4506309 protein tyrosine phosphatase, receptor type, D isofor...   223   2e-58
gi|18860890 protein tyrosine phosphatase, receptor type, D isofo...   223   2e-58
gi|18860892 protein tyrosine phosphatase, receptor type, D isofo...   223   2e-58
gi|18860894 protein tyrosine phosphatase, receptor type, D isofo...   223   2e-58
gi|148539860 protein tyrosine phosphatase, receptor type, T isof...   222   4e-58
gi|148539858 protein tyrosine phosphatase, receptor type, T isof...   222   4e-58
gi|157419150 protein tyrosine phosphatase, receptor type, M isof...   219   3e-57
gi|157419152 protein tyrosine phosphatase, receptor type, M isof...   219   3e-57
gi|18641364 protein tyrosine phosphatase, receptor type, C isofo...   216   4e-56
gi|18641347 protein tyrosine phosphatase, receptor type, C isofo...   216   4e-56
gi|18641362 protein tyrosine phosphatase, receptor type, C isofo...   216   4e-56

>gi|13677222 receptor-type protein tyrosine phosphatase O isoform c
           precursor [Homo sapiens]
          Length = 405

 Score =  833 bits (2152), Expect = 0.0
 Identities = 405/405 (100%), Positives = 405/405 (100%)

Query: 1   MVTEMNPNVVVISVLAILSTLLIGLLLVTLIILRKKHLQMARECGAGTFVNFASLERDGK 60
           MVTEMNPNVVVISVLAILSTLLIGLLLVTLIILRKKHLQMARECGAGTFVNFASLERDGK
Sbjct: 1   MVTEMNPNVVVISVLAILSTLLIGLLLVTLIILRKKHLQMARECGAGTFVNFASLERDGK 60

Query: 61  LPYNWRRSIFAFLTLLPSCLWTDYLLAFYINPWSKNGLKKRKLTNPVQLDDFDAYIKDMA 120
           LPYNWRRSIFAFLTLLPSCLWTDYLLAFYINPWSKNGLKKRKLTNPVQLDDFDAYIKDMA
Sbjct: 61  LPYNWRRSIFAFLTLLPSCLWTDYLLAFYINPWSKNGLKKRKLTNPVQLDDFDAYIKDMA 120

Query: 121 KDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGAD 180
           KDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGAD
Sbjct: 121 KDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGAD 180

Query: 181 YINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYW 240
           YINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYW
Sbjct: 181 YINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYW 240

Query: 241 PFTEEPIAYGDITVEMISEEEQDDWACRHFRINYADEMQDVMHFNYTAWPDHGVPTANAA 300
           PFTEEPIAYGDITVEMISEEEQDDWACRHFRINYADEMQDVMHFNYTAWPDHGVPTANAA
Sbjct: 241 PFTEEPIAYGDITVEMISEEEQDDWACRHFRINYADEMQDVMHFNYTAWPDHGVPTANAA 300

Query: 301 ESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEM 360
           ESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEM
Sbjct: 301 ESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEM 360

Query: 361 RSYRMSMVQTEEQYIFIHQCVQLMWMKKKQQFCISDVIYENVSKS 405
           RSYRMSMVQTEEQYIFIHQCVQLMWMKKKQQFCISDVIYENVSKS
Sbjct: 361 RSYRMSMVQTEEQYIFIHQCVQLMWMKKKQQFCISDVIYENVSKS 405


>gi|13677218 receptor-type protein tyrosine phosphatase O isoform c
           precursor [Homo sapiens]
          Length = 405

 Score =  833 bits (2152), Expect = 0.0
 Identities = 405/405 (100%), Positives = 405/405 (100%)

Query: 1   MVTEMNPNVVVISVLAILSTLLIGLLLVTLIILRKKHLQMARECGAGTFVNFASLERDGK 60
           MVTEMNPNVVVISVLAILSTLLIGLLLVTLIILRKKHLQMARECGAGTFVNFASLERDGK
Sbjct: 1   MVTEMNPNVVVISVLAILSTLLIGLLLVTLIILRKKHLQMARECGAGTFVNFASLERDGK 60

Query: 61  LPYNWRRSIFAFLTLLPSCLWTDYLLAFYINPWSKNGLKKRKLTNPVQLDDFDAYIKDMA 120
           LPYNWRRSIFAFLTLLPSCLWTDYLLAFYINPWSKNGLKKRKLTNPVQLDDFDAYIKDMA
Sbjct: 61  LPYNWRRSIFAFLTLLPSCLWTDYLLAFYINPWSKNGLKKRKLTNPVQLDDFDAYIKDMA 120

Query: 121 KDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGAD 180
           KDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGAD
Sbjct: 121 KDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGAD 180

Query: 181 YINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYW 240
           YINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYW
Sbjct: 181 YINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYW 240

Query: 241 PFTEEPIAYGDITVEMISEEEQDDWACRHFRINYADEMQDVMHFNYTAWPDHGVPTANAA 300
           PFTEEPIAYGDITVEMISEEEQDDWACRHFRINYADEMQDVMHFNYTAWPDHGVPTANAA
Sbjct: 241 PFTEEPIAYGDITVEMISEEEQDDWACRHFRINYADEMQDVMHFNYTAWPDHGVPTANAA 300

Query: 301 ESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEM 360
           ESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEM
Sbjct: 301 ESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEM 360

Query: 361 RSYRMSMVQTEEQYIFIHQCVQLMWMKKKQQFCISDVIYENVSKS 405
           RSYRMSMVQTEEQYIFIHQCVQLMWMKKKQQFCISDVIYENVSKS
Sbjct: 361 RSYRMSMVQTEEQYIFIHQCVQLMWMKKKQQFCISDVIYENVSKS 405


>gi|13677214 receptor-type protein tyrosine phosphatase O isoform a
            precursor [Homo sapiens]
          Length = 1216

 Score =  833 bits (2152), Expect = 0.0
 Identities = 405/405 (100%), Positives = 405/405 (100%)

Query: 1    MVTEMNPNVVVISVLAILSTLLIGLLLVTLIILRKKHLQMARECGAGTFVNFASLERDGK 60
            MVTEMNPNVVVISVLAILSTLLIGLLLVTLIILRKKHLQMARECGAGTFVNFASLERDGK
Sbjct: 812  MVTEMNPNVVVISVLAILSTLLIGLLLVTLIILRKKHLQMARECGAGTFVNFASLERDGK 871

Query: 61   LPYNWRRSIFAFLTLLPSCLWTDYLLAFYINPWSKNGLKKRKLTNPVQLDDFDAYIKDMA 120
            LPYNWRRSIFAFLTLLPSCLWTDYLLAFYINPWSKNGLKKRKLTNPVQLDDFDAYIKDMA
Sbjct: 872  LPYNWRRSIFAFLTLLPSCLWTDYLLAFYINPWSKNGLKKRKLTNPVQLDDFDAYIKDMA 931

Query: 121  KDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGAD 180
            KDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGAD
Sbjct: 932  KDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGAD 991

Query: 181  YINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYW 240
            YINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYW
Sbjct: 992  YINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYW 1051

Query: 241  PFTEEPIAYGDITVEMISEEEQDDWACRHFRINYADEMQDVMHFNYTAWPDHGVPTANAA 300
            PFTEEPIAYGDITVEMISEEEQDDWACRHFRINYADEMQDVMHFNYTAWPDHGVPTANAA
Sbjct: 1052 PFTEEPIAYGDITVEMISEEEQDDWACRHFRINYADEMQDVMHFNYTAWPDHGVPTANAA 1111

Query: 301  ESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEM 360
            ESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEM
Sbjct: 1112 ESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEM 1171

Query: 361  RSYRMSMVQTEEQYIFIHQCVQLMWMKKKQQFCISDVIYENVSKS 405
            RSYRMSMVQTEEQYIFIHQCVQLMWMKKKQQFCISDVIYENVSKS
Sbjct: 1172 RSYRMSMVQTEEQYIFIHQCVQLMWMKKKQQFCISDVIYENVSKS 1216


>gi|13677220 receptor-type protein tyrosine phosphatase O isoform d
           precursor [Homo sapiens]
          Length = 377

 Score =  758 bits (1956), Expect = 0.0
 Identities = 377/405 (93%), Positives = 377/405 (93%), Gaps = 28/405 (6%)

Query: 1   MVTEMNPNVVVISVLAILSTLLIGLLLVTLIILRKKHLQMARECGAGTFVNFASLERDGK 60
           MVTEMNPNVVVISVLAILSTLLIGLLLVTLIILRKKHLQMARECGAGTFVNFASLERDGK
Sbjct: 1   MVTEMNPNVVVISVLAILSTLLIGLLLVTLIILRKKHLQMARECGAGTFVNFASLERDGK 60

Query: 61  LPYNWRRSIFAFLTLLPSCLWTDYLLAFYINPWSKNGLKKRKLTNPVQLDDFDAYIKDMA 120
           LPYNW                            SKNGLKKRKLTNPVQLDDFDAYIKDMA
Sbjct: 61  LPYNW----------------------------SKNGLKKRKLTNPVQLDDFDAYIKDMA 92

Query: 121 KDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGAD 180
           KDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGAD
Sbjct: 93  KDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGAD 152

Query: 181 YINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYW 240
           YINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYW
Sbjct: 153 YINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYW 212

Query: 241 PFTEEPIAYGDITVEMISEEEQDDWACRHFRINYADEMQDVMHFNYTAWPDHGVPTANAA 300
           PFTEEPIAYGDITVEMISEEEQDDWACRHFRINYADEMQDVMHFNYTAWPDHGVPTANAA
Sbjct: 213 PFTEEPIAYGDITVEMISEEEQDDWACRHFRINYADEMQDVMHFNYTAWPDHGVPTANAA 272

Query: 301 ESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEM 360
           ESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEM
Sbjct: 273 ESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEM 332

Query: 361 RSYRMSMVQTEEQYIFIHQCVQLMWMKKKQQFCISDVIYENVSKS 405
           RSYRMSMVQTEEQYIFIHQCVQLMWMKKKQQFCISDVIYENVSKS
Sbjct: 333 RSYRMSMVQTEEQYIFIHQCVQLMWMKKKQQFCISDVIYENVSKS 377


>gi|13677216 receptor-type protein tyrosine phosphatase O isoform d
           precursor [Homo sapiens]
          Length = 377

 Score =  758 bits (1956), Expect = 0.0
 Identities = 377/405 (93%), Positives = 377/405 (93%), Gaps = 28/405 (6%)

Query: 1   MVTEMNPNVVVISVLAILSTLLIGLLLVTLIILRKKHLQMARECGAGTFVNFASLERDGK 60
           MVTEMNPNVVVISVLAILSTLLIGLLLVTLIILRKKHLQMARECGAGTFVNFASLERDGK
Sbjct: 1   MVTEMNPNVVVISVLAILSTLLIGLLLVTLIILRKKHLQMARECGAGTFVNFASLERDGK 60

Query: 61  LPYNWRRSIFAFLTLLPSCLWTDYLLAFYINPWSKNGLKKRKLTNPVQLDDFDAYIKDMA 120
           LPYNW                            SKNGLKKRKLTNPVQLDDFDAYIKDMA
Sbjct: 61  LPYNW----------------------------SKNGLKKRKLTNPVQLDDFDAYIKDMA 92

Query: 121 KDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGAD 180
           KDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGAD
Sbjct: 93  KDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGAD 152

Query: 181 YINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYW 240
           YINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYW
Sbjct: 153 YINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYW 212

Query: 241 PFTEEPIAYGDITVEMISEEEQDDWACRHFRINYADEMQDVMHFNYTAWPDHGVPTANAA 300
           PFTEEPIAYGDITVEMISEEEQDDWACRHFRINYADEMQDVMHFNYTAWPDHGVPTANAA
Sbjct: 213 PFTEEPIAYGDITVEMISEEEQDDWACRHFRINYADEMQDVMHFNYTAWPDHGVPTANAA 272

Query: 301 ESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEM 360
           ESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEM
Sbjct: 273 ESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEM 332

Query: 361 RSYRMSMVQTEEQYIFIHQCVQLMWMKKKQQFCISDVIYENVSKS 405
           RSYRMSMVQTEEQYIFIHQCVQLMWMKKKQQFCISDVIYENVSKS
Sbjct: 333 RSYRMSMVQTEEQYIFIHQCVQLMWMKKKQQFCISDVIYENVSKS 377


>gi|4506323 receptor-type protein tyrosine phosphatase O isoform b
            precursor [Homo sapiens]
          Length = 1188

 Score =  758 bits (1956), Expect = 0.0
 Identities = 377/405 (93%), Positives = 377/405 (93%), Gaps = 28/405 (6%)

Query: 1    MVTEMNPNVVVISVLAILSTLLIGLLLVTLIILRKKHLQMARECGAGTFVNFASLERDGK 60
            MVTEMNPNVVVISVLAILSTLLIGLLLVTLIILRKKHLQMARECGAGTFVNFASLERDGK
Sbjct: 812  MVTEMNPNVVVISVLAILSTLLIGLLLVTLIILRKKHLQMARECGAGTFVNFASLERDGK 871

Query: 61   LPYNWRRSIFAFLTLLPSCLWTDYLLAFYINPWSKNGLKKRKLTNPVQLDDFDAYIKDMA 120
            LPYNW                            SKNGLKKRKLTNPVQLDDFDAYIKDMA
Sbjct: 872  LPYNW----------------------------SKNGLKKRKLTNPVQLDDFDAYIKDMA 903

Query: 121  KDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGAD 180
            KDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGAD
Sbjct: 904  KDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGAD 963

Query: 181  YINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYW 240
            YINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYW
Sbjct: 964  YINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYW 1023

Query: 241  PFTEEPIAYGDITVEMISEEEQDDWACRHFRINYADEMQDVMHFNYTAWPDHGVPTANAA 300
            PFTEEPIAYGDITVEMISEEEQDDWACRHFRINYADEMQDVMHFNYTAWPDHGVPTANAA
Sbjct: 1024 PFTEEPIAYGDITVEMISEEEQDDWACRHFRINYADEMQDVMHFNYTAWPDHGVPTANAA 1083

Query: 301  ESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEM 360
            ESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEM
Sbjct: 1084 ESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEM 1143

Query: 361  RSYRMSMVQTEEQYIFIHQCVQLMWMKKKQQFCISDVIYENVSKS 405
            RSYRMSMVQTEEQYIFIHQCVQLMWMKKKQQFCISDVIYENVSKS
Sbjct: 1144 RSYRMSMVQTEEQYIFIHQCVQLMWMKKKQQFCISDVIYENVSKS 1188


>gi|157952215 protein tyrosine phosphatase, receptor type, B isoform a
            [Homo sapiens]
          Length = 2215

 Score =  297 bits (760), Expect = 1e-80
 Identities = 154/329 (46%), Positives = 217/329 (65%), Gaps = 13/329 (3%)

Query: 83   DYLLAFYINPWSKNGLKKRKLTNPVQLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIP 142
            D  L+ ++N   K     RK + P++++ F+ +   +  DS+Y  S ++EELK +G +  
Sbjct: 1880 DRPLSVHLNLGQKGN---RKTSCPIKINQFEGHFMKLQADSNYLLSKEYEELKDVGRNQS 1936

Query: 143  HFAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGP 202
               A LP NR KNRY NILPYD +RV+L +++++  +DYINA+YIPG N  +EYI TQGP
Sbjct: 1937 CDIALLPENRGKNRYNNILPYDATRVKLSNVDDDPCSDYINASYIPGNNFRREYIVTQGP 1996

Query: 203  LPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQ 262
            LP T++DFWKMV +Q    IVM+TQC EK RVKCDHYWP  ++ + YGD+ ++M+SE   
Sbjct: 1997 LPGTKDDFWKMVWEQNVHNIVMVTQCVEKGRVKCDHYWPADQDSLYYGDLILQMLSESVL 2056

Query: 263  DDWACRHFRI---NYADEMQDVMHFNYTAWPDHGVPTANAAESILQFVHMVRQQATKS-- 317
             +W  R F+I      D  + + HF+YT WPDHGVP     +S++QFV  VR    +S  
Sbjct: 2057 PEWTIREFKICGEEQLDAHRLIRHFHYTVWPDHGVP--ETTQSLIQFVRTVRDYINRSPG 2114

Query: 318  KGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFI 377
             GP ++HCSAGVGRTGTFIALDR+LQ +   + VDI G V ++R +R+ MVQTE QY+++
Sbjct: 2115 AGPTVVHCSAGVGRTGTFIALDRILQQLDSKDSVDIYGAVHDLRLHRVHMVQTECQYVYL 2174

Query: 378  HQCVQLMWMKKK---QQFCISDVIYENVS 403
            HQCV+ +   +K   +Q      IYENV+
Sbjct: 2175 HQCVRDVLRARKLRSEQENPLFPIYENVN 2203


>gi|157952213 protein tyrosine phosphatase, receptor type, B isoform b
            precursor [Homo sapiens]
          Length = 1997

 Score =  297 bits (760), Expect = 1e-80
 Identities = 154/329 (46%), Positives = 217/329 (65%), Gaps = 13/329 (3%)

Query: 83   DYLLAFYINPWSKNGLKKRKLTNPVQLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIP 142
            D  L+ ++N   K     RK + P++++ F+ +   +  DS+Y  S ++EELK +G +  
Sbjct: 1662 DRPLSVHLNLGQKGN---RKTSCPIKINQFEGHFMKLQADSNYLLSKEYEELKDVGRNQS 1718

Query: 143  HFAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGP 202
               A LP NR KNRY NILPYD +RV+L +++++  +DYINA+YIPG N  +EYI TQGP
Sbjct: 1719 CDIALLPENRGKNRYNNILPYDATRVKLSNVDDDPCSDYINASYIPGNNFRREYIVTQGP 1778

Query: 203  LPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQ 262
            LP T++DFWKMV +Q    IVM+TQC EK RVKCDHYWP  ++ + YGD+ ++M+SE   
Sbjct: 1779 LPGTKDDFWKMVWEQNVHNIVMVTQCVEKGRVKCDHYWPADQDSLYYGDLILQMLSESVL 1838

Query: 263  DDWACRHFRI---NYADEMQDVMHFNYTAWPDHGVPTANAAESILQFVHMVRQQATKS-- 317
             +W  R F+I      D  + + HF+YT WPDHGVP     +S++QFV  VR    +S  
Sbjct: 1839 PEWTIREFKICGEEQLDAHRLIRHFHYTVWPDHGVP--ETTQSLIQFVRTVRDYINRSPG 1896

Query: 318  KGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFI 377
             GP ++HCSAGVGRTGTFIALDR+LQ +   + VDI G V ++R +R+ MVQTE QY+++
Sbjct: 1897 AGPTVVHCSAGVGRTGTFIALDRILQQLDSKDSVDIYGAVHDLRLHRVHMVQTECQYVYL 1956

Query: 378  HQCVQLMWMKKK---QQFCISDVIYENVS 403
            HQCV+ +   +K   +Q      IYENV+
Sbjct: 1957 HQCVRDVLRARKLRSEQENPLFPIYENVN 1985


>gi|222537743 protein tyrosine phosphatase, receptor type, Q [Homo
            sapiens]
          Length = 2299

 Score =  283 bits (723), Expect = 3e-76
 Identities = 142/308 (46%), Positives = 192/308 (62%), Gaps = 3/308 (0%)

Query: 98   LKKRKLTNPVQLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRY 157
            L  RK   P+    F  +++++  +++ KF  +F EL     D+    ADLP NR KNR+
Sbjct: 1974 LSYRKSIKPISKKSFLQHVEELCTNNNLKFQEEFSELPKFLQDLSSTDADLPWNRAKNRF 2033

Query: 158  TNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQ 217
             NI PY+ +RV+L++     G+DYINA+YI GY  P E+IATQGPLP T  DFW+MV + 
Sbjct: 2034 PNIKPYNNNRVKLIADASVPGSDYINASYISGYLCPNEFIATQGPLPGTVGDFWRMVWET 2093

Query: 218  KSQIIVMLTQCNEKRRVKCDHYWPFTEEPI-AYGDITVEMISEEEQDDWACRHFRINYAD 276
            +++ +VMLTQC EK R++C  YWP   +P+  +GDI +  + E+ Q DW  R  +I    
Sbjct: 2094 RAKTLVMLTQCFEKGRIRCHQYWPEDNKPVTVFGDIVITKLMEDVQIDWTIRDLKIERHG 2153

Query: 277  EMQDVMHFNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFI 336
            +   V   N+TAWP+HGVP  +A   ++ FV +VR        PMI+HCSAGVGRTG FI
Sbjct: 2154 DCMTVRQCNFTAWPEHGVPENSA--PLIHFVKLVRASRAHDTTPMIVHCSAGVGRTGVFI 2211

Query: 337  ALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWMKKKQQFCISD 396
            ALD L QHI DH+FVDI GLV+E+RS RM MVQ   QYIF+HQC+  +   K     I  
Sbjct: 2212 ALDHLTQHINDHDFVDIYGLVAELRSERMCMVQNLAQYIFLHQCILDLLSNKGSNQPICF 2271

Query: 397  VIYENVSK 404
            V Y  + K
Sbjct: 2272 VNYSALQK 2279


>gi|148728162 protein tyrosine phosphatase, receptor type, J isoform 1
            precursor [Homo sapiens]
          Length = 1337

 Score =  278 bits (711), Expect = 6e-75
 Identities = 138/308 (44%), Positives = 208/308 (67%), Gaps = 10/308 (3%)

Query: 100  KRKLTNPVQLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTN 159
            K K +  +++++F+AY K    DS+  F+ ++E+LKL+G+  P +AA+L  NR KNRY N
Sbjct: 1014 KPKKSKLIRVENFEAYFKKQQADSNCGFAEEYEDLKLVGISQPKYAAELAENRGKNRYNN 1073

Query: 160  ILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKS 219
            +LPYD SRV+L S+      DYINANY+PGY+S +++IATQGPLP T  DFW+MV ++  
Sbjct: 1074 VLPYDISRVKL-SVQTHSTDDYINANYMPGYHSKKDFIATQGPLPNTLKDFWRMVWEKNV 1132

Query: 220  QIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDDWACRHFRIN--YADE 277
              I+MLT+C E+ R KC+ YWP +++   YGDITV M SE    +W  R F +      E
Sbjct: 1133 YAIIMLTKCVEQGRTKCEEYWP-SKQAQDYGDITVAMTSEIVLPEWTIRDFTVKNIQTSE 1191

Query: 278  MQDVMHFNYTAWPDHGVPTANAAESILQFVHMVRQQATKS--KGPMIIHCSAGVGRTGTF 335
               +  F++T+WPDHGVP  +  + ++ F ++VR    +S  + P+++HCSAGVGRTGTF
Sbjct: 1192 SHPLRQFHFTSWPDHGVP--DTTDLLINFRYLVRDYMKQSPPESPILVHCSAGVGRTGTF 1249

Query: 336  IALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWMKKKQQFCIS 395
            IA+DRL+  I +   VD+ G+V ++R +R  MVQTE+QY+F++QCV  + + + Q+    
Sbjct: 1250 IAIDRLIYQIENENTVDVYGIVYDLRMHRPLMVQTEDQYVFLNQCV--LDIVRSQKDSKV 1307

Query: 396  DVIYENVS 403
            D+IY+N +
Sbjct: 1308 DLIYQNTT 1315


>gi|241896926 protein tyrosine phosphatase, receptor type, H isoform
           2 precursor [Homo sapiens]
          Length = 937

 Score =  268 bits (686), Expect = 5e-72
 Identities = 137/329 (41%), Positives = 201/329 (61%), Gaps = 13/329 (3%)

Query: 85  LLAFYINPWSKNGLKKRKLTN-------PVQLDDFDAYIKDMAKDSDYKFSLQFEELKLI 137
           LL F++   +K   +K +L +        +  +DF  +++   +DS+  F+ ++++L L+
Sbjct: 593 LLIFFLKRRNKKKQQKPELRDLVFSSPGDIPAEDFADHVRKNERDSNCGFADKYQQLSLV 652

Query: 138 GLDIPHFAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYI 197
           G       A    N  KNRY N+LPYD+SRV L  ++EE G+DYINA+++PG  SPQE+I
Sbjct: 653 GHSQSQMVASASENNAKNRYRNVLPYDWSRVPLKPIHEEPGSDYINASFMPGLWSPQEFI 712

Query: 198 ATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDITVEMI 257
           ATQGPLP+T  DFW++V +Q+S  +VMLT C E  RVKC+HYWP   +P  +G + V ++
Sbjct: 713 ATQGPLPQTVGDFWRLVWEQQSHTLVMLTNCMEAGRVKCEHYWPLDSQPCTHGHLRVTLV 772

Query: 258 SEEEQDDWACRHFRINYADEMQ--DVMHFNYTAWPDHGVPTANAAESILQFVHMVRQ--Q 313
            EE  ++W  R   +   +E +   V  F+Y AWPDHGVP  ++ +++L F  M+RQ   
Sbjct: 773 GEEVMENWTVRELLLLQVEEQKTLSVRQFHYQAWPDHGVP--SSPDTLLAFWRMLRQWLD 830

Query: 314 ATKSKGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQ 373
            T   GP I+HCSAGVGRTGT IALD LL+ ++    +     V +MR  R  MVQTE Q
Sbjct: 831 QTMEGGPPIVHCSAGVGRTGTLIALDVLLRQLQSEGLLGPFSFVRKMRESRPLMVQTEAQ 890

Query: 374 YIFIHQCVQLMWMKKKQQFCISDVIYENV 402
           Y+F+HQC+     +  Q     +V YE+V
Sbjct: 891 YVFLHQCILRFLQQSAQAPAEKEVPYEDV 919


>gi|241896924 protein tyrosine phosphatase, receptor type, H isoform 1
            precursor [Homo sapiens]
          Length = 1115

 Score =  268 bits (686), Expect = 5e-72
 Identities = 137/329 (41%), Positives = 201/329 (61%), Gaps = 13/329 (3%)

Query: 85   LLAFYINPWSKNGLKKRKLTN-------PVQLDDFDAYIKDMAKDSDYKFSLQFEELKLI 137
            LL F++   +K   +K +L +        +  +DF  +++   +DS+  F+ ++++L L+
Sbjct: 771  LLIFFLKRRNKKKQQKPELRDLVFSSPGDIPAEDFADHVRKNERDSNCGFADKYQQLSLV 830

Query: 138  GLDIPHFAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYI 197
            G       A    N  KNRY N+LPYD+SRV L  ++EE G+DYINA+++PG  SPQE+I
Sbjct: 831  GHSQSQMVASASENNAKNRYRNVLPYDWSRVPLKPIHEEPGSDYINASFMPGLWSPQEFI 890

Query: 198  ATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDITVEMI 257
            ATQGPLP+T  DFW++V +Q+S  +VMLT C E  RVKC+HYWP   +P  +G + V ++
Sbjct: 891  ATQGPLPQTVGDFWRLVWEQQSHTLVMLTNCMEAGRVKCEHYWPLDSQPCTHGHLRVTLV 950

Query: 258  SEEEQDDWACRHFRINYADEMQ--DVMHFNYTAWPDHGVPTANAAESILQFVHMVRQ--Q 313
             EE  ++W  R   +   +E +   V  F+Y AWPDHGVP  ++ +++L F  M+RQ   
Sbjct: 951  GEEVMENWTVRELLLLQVEEQKTLSVRQFHYQAWPDHGVP--SSPDTLLAFWRMLRQWLD 1008

Query: 314  ATKSKGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQ 373
             T   GP I+HCSAGVGRTGT IALD LL+ ++    +     V +MR  R  MVQTE Q
Sbjct: 1009 QTMEGGPPIVHCSAGVGRTGTLIALDVLLRQLQSEGLLGPFSFVRKMRESRPLMVQTEAQ 1068

Query: 374  YIFIHQCVQLMWMKKKQQFCISDVIYENV 402
            Y+F+HQC+     +  Q     +V YE+V
Sbjct: 1069 YVFLHQCILRFLQQSAQAPAEKEVPYEDV 1097


>gi|109633041 protein tyrosine phosphatase, receptor type, F isoform 1
            precursor [Homo sapiens]
          Length = 1907

 Score =  225 bits (574), Expect = 5e-59
 Identities = 119/278 (42%), Positives = 168/278 (60%), Gaps = 6/278 (2%)

Query: 106  PVQLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDF 165
            P+ + D    I+ +  +   KFS ++E +   G       ++L +N+ KNRY N++ YD 
Sbjct: 1331 PIPITDLADNIERLKANDGLKFSQEYESIDP-GQQFTWENSNLEVNKPKNRYANVIAYDH 1389

Query: 166  SRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVML 225
            SRV L S++   G+DYINANYI GY     YIATQGPLPET  DFW+MV +Q++  +VM+
Sbjct: 1390 SRVILTSIDGVPGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRTATVVMM 1449

Query: 226  TQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDDWACRHFRINY--ADEMQDVMH 283
            T+  EK RVKCD YWP        G I V ++   E   +  R F ++   + E +++  
Sbjct: 1450 TRLEEKSRVKCDQYWP-ARGTETCGLIQVTLLDTVELATYTVRTFALHKSGSSEKRELRQ 1508

Query: 284  FNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQ 343
            F + AWPDHGVP       IL F+  V+       GPM++HCSAGVGRTG FI +D +L+
Sbjct: 1509 FQFMAWPDHGVP--EYPTPILAFLRRVKACNPLDAGPMVVHCSAGVGRTGCFIVIDAMLE 1566

Query: 344  HIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCV 381
             ++  + VDI G V+ MRS R  MVQTE+QY+FIH+ +
Sbjct: 1567 RMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEAL 1604



 Score =  188 bits (477), Expect = 9e-48
 Identities = 103/251 (41%), Positives = 145/251 (57%), Gaps = 13/251 (5%)

Query: 133  ELKLIGLDIPH----FAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIP 188
            E KL+     H     +A+LP N+ KNR  NI+PY+ +RV L  +   EG+DYINA+++ 
Sbjct: 1642 EFKLLASSKAHTSRFISANLPCNKFKNRLVNIMPYELTRVCLQPIRGVEGSDYINASFLD 1701

Query: 189  GYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIA 248
            GY   + YIATQGPL E+  DFW+M+ +  S IIVMLT+  E  R KC  YWP  E    
Sbjct: 1702 GYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWP-AERSAR 1760

Query: 249  YGDITVEMISEEEQDDWACRHFRINYADEMQD--VMHFNYTAWPDHGVPTANAAESILQF 306
            Y    V+ ++E     +  R F++  A + Q   +  F +T WP+ GVP     E  + F
Sbjct: 1761 YQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVP--KTGEGFIDF 1818

Query: 307  ---VHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSY 363
               VH  ++Q  +  GP+ +HCSAGVGRTG FI L  +L+ +R    VD+   V  +R+ 
Sbjct: 1819 IGQVHKTKEQFGQD-GPITVHCSAGVGRTGVFITLSIVLERMRYEGVVDMFQTVKTLRTQ 1877

Query: 364  RMSMVQTEEQY 374
            R +MVQTE+QY
Sbjct: 1878 RPAMVQTEDQY 1888


>gi|109633039 protein tyrosine phosphatase, receptor type, F isoform 2
            precursor [Homo sapiens]
          Length = 1898

 Score =  225 bits (574), Expect = 5e-59
 Identities = 119/278 (42%), Positives = 168/278 (60%), Gaps = 6/278 (2%)

Query: 106  PVQLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDF 165
            P+ + D    I+ +  +   KFS ++E +   G       ++L +N+ KNRY N++ YD 
Sbjct: 1322 PIPITDLADNIERLKANDGLKFSQEYESIDP-GQQFTWENSNLEVNKPKNRYANVIAYDH 1380

Query: 166  SRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVML 225
            SRV L S++   G+DYINANYI GY     YIATQGPLPET  DFW+MV +Q++  +VM+
Sbjct: 1381 SRVILTSIDGVPGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRTATVVMM 1440

Query: 226  TQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDDWACRHFRINY--ADEMQDVMH 283
            T+  EK RVKCD YWP        G I V ++   E   +  R F ++   + E +++  
Sbjct: 1441 TRLEEKSRVKCDQYWP-ARGTETCGLIQVTLLDTVELATYTVRTFALHKSGSSEKRELRQ 1499

Query: 284  FNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQ 343
            F + AWPDHGVP       IL F+  V+       GPM++HCSAGVGRTG FI +D +L+
Sbjct: 1500 FQFMAWPDHGVP--EYPTPILAFLRRVKACNPLDAGPMVVHCSAGVGRTGCFIVIDAMLE 1557

Query: 344  HIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCV 381
             ++  + VDI G V+ MRS R  MVQTE+QY+FIH+ +
Sbjct: 1558 RMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEAL 1595



 Score =  188 bits (477), Expect = 9e-48
 Identities = 103/251 (41%), Positives = 145/251 (57%), Gaps = 13/251 (5%)

Query: 133  ELKLIGLDIPH----FAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIP 188
            E KL+     H     +A+LP N+ KNR  NI+PY+ +RV L  +   EG+DYINA+++ 
Sbjct: 1633 EFKLLASSKAHTSRFISANLPCNKFKNRLVNIMPYELTRVCLQPIRGVEGSDYINASFLD 1692

Query: 189  GYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIA 248
            GY   + YIATQGPL E+  DFW+M+ +  S IIVMLT+  E  R KC  YWP  E    
Sbjct: 1693 GYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWP-AERSAR 1751

Query: 249  YGDITVEMISEEEQDDWACRHFRINYADEMQD--VMHFNYTAWPDHGVPTANAAESILQF 306
            Y    V+ ++E     +  R F++  A + Q   +  F +T WP+ GVP     E  + F
Sbjct: 1752 YQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVP--KTGEGFIDF 1809

Query: 307  ---VHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSY 363
               VH  ++Q  +  GP+ +HCSAGVGRTG FI L  +L+ +R    VD+   V  +R+ 
Sbjct: 1810 IGQVHKTKEQFGQD-GPITVHCSAGVGRTGVFITLSIVLERMRYEGVVDMFQTVKTLRTQ 1868

Query: 364  RMSMVQTEEQY 374
            R +MVQTE+QY
Sbjct: 1869 RPAMVQTEDQY 1879


>gi|104487611 protein tyrosine phosphatase, receptor type, sigma
            isoform 4 precursor [Homo sapiens]
          Length = 1505

 Score =  223 bits (569), Expect = 2e-58
 Identities = 118/278 (42%), Positives = 165/278 (59%), Gaps = 6/278 (2%)

Query: 106  PVQLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDF 165
            P+ + D   + + +  +   K S ++E +   G       ++L +N+ KNRY N++ YD 
Sbjct: 929  PIPIADMAEHTERLKANDSLKLSQEYESIDP-GQQFTWEHSNLEVNKPKNRYANVIAYDH 987

Query: 166  SRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVML 225
            SRV L  +    G+DYINANY+ GY     YIATQGPLPET  DFW+MV +Q+S  IVM+
Sbjct: 988  SRVILQPIEGIMGSDYINANYVDGYRCQNAYIATQGPLPETFGDFWRMVWEQRSATIVMM 1047

Query: 226  TQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDDWACRHFRI--NYADEMQDVMH 283
            T+  EK R+KCD YWP       YG I V ++   E   +  R F +  N + E ++V  
Sbjct: 1048 TRLEEKSRIKCDQYWP-NRGTETYGFIQVTLLDTIELATFCVRTFSLHKNGSSEKREVRQ 1106

Query: 284  FNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQ 343
            F +TAWPDHGVP        L F+  V+       GP+++HCSAGVGRTG FI +D +L+
Sbjct: 1107 FQFTAWPDHGVP--EYPTPFLAFLRRVKTCNPPDAGPIVVHCSAGVGRTGCFIVIDAMLE 1164

Query: 344  HIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCV 381
             I+  + VD+ G V+ MRS R  MVQTE+QY FIH+ +
Sbjct: 1165 RIKPEKTVDVYGHVTLMRSQRNYMVQTEDQYSFIHEAL 1202



 Score =  191 bits (486), Expect = 8e-49
 Identities = 103/240 (42%), Positives = 144/240 (60%), Gaps = 9/240 (3%)

Query: 145  AADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLP 204
            +A+LP N+ KNR  NI+PY+ +RV L  +   EG+DYINA++I GY   + YIATQGPL 
Sbjct: 1256 SANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLA 1315

Query: 205  ETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDD 264
            ET  DFW+M+ +  S I+VMLT+  E  R KC  YWP  E    Y    V+ ++E     
Sbjct: 1316 ETTEDFWRMLWENNSTIVVMLTKLREMGREKCHQYWP-AERSARYQYFVVDPMAEYNMPQ 1374

Query: 265  WACRHFRINYADEMQD--VMHFNYTAWPDHGVPTANAAESILQF---VHMVRQQATKSKG 319
            +  R F++  A + Q   V  F +T WP+ GVP   + E  + F   VH  ++Q  +  G
Sbjct: 1375 YILREFKVTDARDGQSRTVRQFQFTDWPEQGVP--KSGEGFIDFIGQVHKTKEQFGQD-G 1431

Query: 320  PMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQ 379
            P+ +HCSAGVGRTG FI L  +L+ +R    VDI   V  +R+ R +MVQTE++Y F +Q
Sbjct: 1432 PISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDEYQFCYQ 1491


>gi|104487297 protein tyrosine phosphatase, receptor type, sigma
            isoform 2 precursor [Homo sapiens]
          Length = 1910

 Score =  223 bits (569), Expect = 2e-58
 Identities = 118/278 (42%), Positives = 165/278 (59%), Gaps = 6/278 (2%)

Query: 106  PVQLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDF 165
            P+ + D   + + +  +   K S ++E +   G       ++L +N+ KNRY N++ YD 
Sbjct: 1334 PIPIADMAEHTERLKANDSLKLSQEYESIDP-GQQFTWEHSNLEVNKPKNRYANVIAYDH 1392

Query: 166  SRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVML 225
            SRV L  +    G+DYINANY+ GY     YIATQGPLPET  DFW+MV +Q+S  IVM+
Sbjct: 1393 SRVILQPIEGIMGSDYINANYVDGYRCQNAYIATQGPLPETFGDFWRMVWEQRSATIVMM 1452

Query: 226  TQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDDWACRHFRI--NYADEMQDVMH 283
            T+  EK R+KCD YWP       YG I V ++   E   +  R F +  N + E ++V  
Sbjct: 1453 TRLEEKSRIKCDQYWP-NRGTETYGFIQVTLLDTIELATFCVRTFSLHKNGSSEKREVRQ 1511

Query: 284  FNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQ 343
            F +TAWPDHGVP        L F+  V+       GP+++HCSAGVGRTG FI +D +L+
Sbjct: 1512 FQFTAWPDHGVP--EYPTPFLAFLRRVKTCNPPDAGPIVVHCSAGVGRTGCFIVIDAMLE 1569

Query: 344  HIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCV 381
             I+  + VD+ G V+ MRS R  MVQTE+QY FIH+ +
Sbjct: 1570 RIKPEKTVDVYGHVTLMRSQRNYMVQTEDQYSFIHEAL 1607



 Score =  191 bits (486), Expect = 8e-49
 Identities = 103/240 (42%), Positives = 144/240 (60%), Gaps = 9/240 (3%)

Query: 145  AADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLP 204
            +A+LP N+ KNR  NI+PY+ +RV L  +   EG+DYINA++I GY   + YIATQGPL 
Sbjct: 1661 SANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLA 1720

Query: 205  ETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDD 264
            ET  DFW+M+ +  S I+VMLT+  E  R KC  YWP  E    Y    V+ ++E     
Sbjct: 1721 ETTEDFWRMLWENNSTIVVMLTKLREMGREKCHQYWP-AERSARYQYFVVDPMAEYNMPQ 1779

Query: 265  WACRHFRINYADEMQD--VMHFNYTAWPDHGVPTANAAESILQF---VHMVRQQATKSKG 319
            +  R F++  A + Q   V  F +T WP+ GVP   + E  + F   VH  ++Q  +  G
Sbjct: 1780 YILREFKVTDARDGQSRTVRQFQFTDWPEQGVP--KSGEGFIDFIGQVHKTKEQFGQD-G 1836

Query: 320  PMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQ 379
            P+ +HCSAGVGRTG FI L  +L+ +R    VDI   V  +R+ R +MVQTE++Y F +Q
Sbjct: 1837 PISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDEYQFCYQ 1896


>gi|104487295 protein tyrosine phosphatase, receptor type, sigma
            isoform 3 precursor [Homo sapiens]
          Length = 1501

 Score =  223 bits (569), Expect = 2e-58
 Identities = 118/278 (42%), Positives = 165/278 (59%), Gaps = 6/278 (2%)

Query: 106  PVQLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDF 165
            P+ + D   + + +  +   K S ++E +   G       ++L +N+ KNRY N++ YD 
Sbjct: 925  PIPIADMAEHTERLKANDSLKLSQEYESIDP-GQQFTWEHSNLEVNKPKNRYANVIAYDH 983

Query: 166  SRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVML 225
            SRV L  +    G+DYINANY+ GY     YIATQGPLPET  DFW+MV +Q+S  IVM+
Sbjct: 984  SRVILQPIEGIMGSDYINANYVDGYRCQNAYIATQGPLPETFGDFWRMVWEQRSATIVMM 1043

Query: 226  TQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDDWACRHFRI--NYADEMQDVMH 283
            T+  EK R+KCD YWP       YG I V ++   E   +  R F +  N + E ++V  
Sbjct: 1044 TRLEEKSRIKCDQYWP-NRGTETYGFIQVTLLDTIELATFCVRTFSLHKNGSSEKREVRQ 1102

Query: 284  FNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQ 343
            F +TAWPDHGVP        L F+  V+       GP+++HCSAGVGRTG FI +D +L+
Sbjct: 1103 FQFTAWPDHGVP--EYPTPFLAFLRRVKTCNPPDAGPIVVHCSAGVGRTGCFIVIDAMLE 1160

Query: 344  HIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCV 381
             I+  + VD+ G V+ MRS R  MVQTE+QY FIH+ +
Sbjct: 1161 RIKPEKTVDVYGHVTLMRSQRNYMVQTEDQYSFIHEAL 1198



 Score =  191 bits (486), Expect = 8e-49
 Identities = 103/240 (42%), Positives = 144/240 (60%), Gaps = 9/240 (3%)

Query: 145  AADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLP 204
            +A+LP N+ KNR  NI+PY+ +RV L  +   EG+DYINA++I GY   + YIATQGPL 
Sbjct: 1252 SANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLA 1311

Query: 205  ETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDD 264
            ET  DFW+M+ +  S I+VMLT+  E  R KC  YWP  E    Y    V+ ++E     
Sbjct: 1312 ETTEDFWRMLWENNSTIVVMLTKLREMGREKCHQYWP-AERSARYQYFVVDPMAEYNMPQ 1370

Query: 265  WACRHFRINYADEMQD--VMHFNYTAWPDHGVPTANAAESILQF---VHMVRQQATKSKG 319
            +  R F++  A + Q   V  F +T WP+ GVP   + E  + F   VH  ++Q  +  G
Sbjct: 1371 YILREFKVTDARDGQSRTVRQFQFTDWPEQGVP--KSGEGFIDFIGQVHKTKEQFGQD-G 1427

Query: 320  PMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQ 379
            P+ +HCSAGVGRTG FI L  +L+ +R    VDI   V  +R+ R +MVQTE++Y F +Q
Sbjct: 1428 PISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDEYQFCYQ 1487


>gi|104487006 protein tyrosine phosphatase, receptor type, sigma
            isoform 1 precursor [Homo sapiens]
          Length = 1948

 Score =  223 bits (569), Expect = 2e-58
 Identities = 118/278 (42%), Positives = 165/278 (59%), Gaps = 6/278 (2%)

Query: 106  PVQLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDF 165
            P+ + D   + + +  +   K S ++E +   G       ++L +N+ KNRY N++ YD 
Sbjct: 1372 PIPIADMAEHTERLKANDSLKLSQEYESIDP-GQQFTWEHSNLEVNKPKNRYANVIAYDH 1430

Query: 166  SRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVML 225
            SRV L  +    G+DYINANY+ GY     YIATQGPLPET  DFW+MV +Q+S  IVM+
Sbjct: 1431 SRVILQPIEGIMGSDYINANYVDGYRCQNAYIATQGPLPETFGDFWRMVWEQRSATIVMM 1490

Query: 226  TQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDDWACRHFRI--NYADEMQDVMH 283
            T+  EK R+KCD YWP       YG I V ++   E   +  R F +  N + E ++V  
Sbjct: 1491 TRLEEKSRIKCDQYWP-NRGTETYGFIQVTLLDTIELATFCVRTFSLHKNGSSEKREVRQ 1549

Query: 284  FNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQ 343
            F +TAWPDHGVP        L F+  V+       GP+++HCSAGVGRTG FI +D +L+
Sbjct: 1550 FQFTAWPDHGVP--EYPTPFLAFLRRVKTCNPPDAGPIVVHCSAGVGRTGCFIVIDAMLE 1607

Query: 344  HIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCV 381
             I+  + VD+ G V+ MRS R  MVQTE+QY FIH+ +
Sbjct: 1608 RIKPEKTVDVYGHVTLMRSQRNYMVQTEDQYSFIHEAL 1645



 Score =  191 bits (486), Expect = 8e-49
 Identities = 103/240 (42%), Positives = 144/240 (60%), Gaps = 9/240 (3%)

Query: 145  AADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLP 204
            +A+LP N+ KNR  NI+PY+ +RV L  +   EG+DYINA++I GY   + YIATQGPL 
Sbjct: 1699 SANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLA 1758

Query: 205  ETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDD 264
            ET  DFW+M+ +  S I+VMLT+  E  R KC  YWP  E    Y    V+ ++E     
Sbjct: 1759 ETTEDFWRMLWENNSTIVVMLTKLREMGREKCHQYWP-AERSARYQYFVVDPMAEYNMPQ 1817

Query: 265  WACRHFRINYADEMQD--VMHFNYTAWPDHGVPTANAAESILQF---VHMVRQQATKSKG 319
            +  R F++  A + Q   V  F +T WP+ GVP   + E  + F   VH  ++Q  +  G
Sbjct: 1818 YILREFKVTDARDGQSRTVRQFQFTDWPEQGVP--KSGEGFIDFIGQVHKTKEQFGQD-G 1874

Query: 320  PMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQ 379
            P+ +HCSAGVGRTG FI L  +L+ +R    VDI   V  +R+ R +MVQTE++Y F +Q
Sbjct: 1875 PISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDEYQFCYQ 1934


>gi|104487002 protein tyrosine phosphatase, receptor type, D isoform 5
            precursor [Homo sapiens]
          Length = 1502

 Score =  223 bits (569), Expect = 2e-58
 Identities = 116/278 (41%), Positives = 169/278 (60%), Gaps = 6/278 (2%)

Query: 106  PVQLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDF 165
            P+ + +   +I+ +  + + KFS ++E +   G       ++L +N+ KNRY N++ YD 
Sbjct: 926  PIPILELADHIERLKANDNLKFSQEYESIDP-GQQFTWEHSNLEVNKPKNRYANVIAYDH 984

Query: 166  SRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVML 225
            SRV L ++    G+DY+NANYI GY     YIATQG LPET  DFW+M+ +Q+S  +VM+
Sbjct: 985  SRVLLSAIEGIPGSDYVNANYIDGYRKQNAYIATQGSLPETFGDFWRMIWEQRSATVVMM 1044

Query: 226  TQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDDWACRHFRI--NYADEMQDVMH 283
            T+  E+ RVKCD YWP +     +G + V ++   E   +  R F +  N + E ++V  
Sbjct: 1045 TKLEERSRVKCDQYWP-SRGTETHGLVQVTLLDTVELATYCVRTFALYKNGSSEKREVRQ 1103

Query: 284  FNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQ 343
            F +TAWPDHGVP        L F+  V+       GPM++HCSAGVGRTG FI +D +L+
Sbjct: 1104 FQFTAWPDHGVP--EHPTPFLAFLRRVKTCNPPDAGPMVVHCSAGVGRTGCFIVIDAMLE 1161

Query: 344  HIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCV 381
             I+  + VDI G V+ MR+ R  MVQTE+QYIFIH  +
Sbjct: 1162 RIKHEKTVDIYGHVTLMRAQRNYMVQTEDQYIFIHDAL 1199



 Score =  191 bits (484), Expect = 1e-48
 Identities = 103/240 (42%), Positives = 144/240 (60%), Gaps = 9/240 (3%)

Query: 145  AADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLP 204
            +A+LP N+ KNR  NI+PY+ +RV L  +   EG+DYINA++I GY   + YIATQGPL 
Sbjct: 1253 SANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLA 1312

Query: 205  ETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDD 264
            ET  DFW+M+ +  S I+VMLT+  E  R KC  YWP  E    Y    V+ ++E     
Sbjct: 1313 ETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWP-AERSARYQYFVVDPMAEYNMPQ 1371

Query: 265  WACRHFRINYADEMQD--VMHFNYTAWPDHGVPTANAAESILQF---VHMVRQQATKSKG 319
            +  R F++  A + Q   V  F +T WP+ GVP   + E  + F   VH  ++Q  +  G
Sbjct: 1372 YILREFKVTDARDGQSRTVRQFQFTDWPEQGVP--KSGEGFIDFIGQVHKTKEQFGQD-G 1428

Query: 320  PMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQ 379
            P+ +HCSAGVGRTG FI L  +L+ +R    VDI   V  +R+ R +MVQTE+QY F ++
Sbjct: 1429 PISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDQYQFSYR 1488


>gi|4506309 protein tyrosine phosphatase, receptor type, D isoform 1
            precursor [Homo sapiens]
          Length = 1912

 Score =  223 bits (569), Expect = 2e-58
 Identities = 116/278 (41%), Positives = 169/278 (60%), Gaps = 6/278 (2%)

Query: 106  PVQLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDF 165
            P+ + +   +I+ +  + + KFS ++E +   G       ++L +N+ KNRY N++ YD 
Sbjct: 1336 PIPILELADHIERLKANDNLKFSQEYESIDP-GQQFTWEHSNLEVNKPKNRYANVIAYDH 1394

Query: 166  SRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVML 225
            SRV L ++    G+DY+NANYI GY     YIATQG LPET  DFW+M+ +Q+S  +VM+
Sbjct: 1395 SRVLLSAIEGIPGSDYVNANYIDGYRKQNAYIATQGSLPETFGDFWRMIWEQRSATVVMM 1454

Query: 226  TQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDDWACRHFRI--NYADEMQDVMH 283
            T+  E+ RVKCD YWP +     +G + V ++   E   +  R F +  N + E ++V  
Sbjct: 1455 TKLEERSRVKCDQYWP-SRGTETHGLVQVTLLDTVELATYCVRTFALYKNGSSEKREVRQ 1513

Query: 284  FNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQ 343
            F +TAWPDHGVP        L F+  V+       GPM++HCSAGVGRTG FI +D +L+
Sbjct: 1514 FQFTAWPDHGVP--EHPTPFLAFLRRVKTCNPPDAGPMVVHCSAGVGRTGCFIVIDAMLE 1571

Query: 344  HIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCV 381
             I+  + VDI G V+ MR+ R  MVQTE+QYIFIH  +
Sbjct: 1572 RIKHEKTVDIYGHVTLMRAQRNYMVQTEDQYIFIHDAL 1609



 Score =  191 bits (484), Expect = 1e-48
 Identities = 103/240 (42%), Positives = 144/240 (60%), Gaps = 9/240 (3%)

Query: 145  AADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLP 204
            +A+LP N+ KNR  NI+PY+ +RV L  +   EG+DYINA++I GY   + YIATQGPL 
Sbjct: 1663 SANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLA 1722

Query: 205  ETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDD 264
            ET  DFW+M+ +  S I+VMLT+  E  R KC  YWP  E    Y    V+ ++E     
Sbjct: 1723 ETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWP-AERSARYQYFVVDPMAEYNMPQ 1781

Query: 265  WACRHFRINYADEMQD--VMHFNYTAWPDHGVPTANAAESILQF---VHMVRQQATKSKG 319
            +  R F++  A + Q   V  F +T WP+ GVP   + E  + F   VH  ++Q  +  G
Sbjct: 1782 YILREFKVTDARDGQSRTVRQFQFTDWPEQGVP--KSGEGFIDFIGQVHKTKEQFGQD-G 1838

Query: 320  PMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQ 379
            P+ +HCSAGVGRTG FI L  +L+ +R    VDI   V  +R+ R +MVQTE+QY F ++
Sbjct: 1839 PISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDQYQFSYR 1898


>gi|18860890 protein tyrosine phosphatase, receptor type, D isoform 2
            precursor [Homo sapiens]
          Length = 1899

 Score =  223 bits (569), Expect = 2e-58
 Identities = 116/278 (41%), Positives = 169/278 (60%), Gaps = 6/278 (2%)

Query: 106  PVQLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDF 165
            P+ + +   +I+ +  + + KFS ++E +   G       ++L +N+ KNRY N++ YD 
Sbjct: 1323 PIPILELADHIERLKANDNLKFSQEYESIDP-GQQFTWEHSNLEVNKPKNRYANVIAYDH 1381

Query: 166  SRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVML 225
            SRV L ++    G+DY+NANYI GY     YIATQG LPET  DFW+M+ +Q+S  +VM+
Sbjct: 1382 SRVLLSAIEGIPGSDYVNANYIDGYRKQNAYIATQGSLPETFGDFWRMIWEQRSATVVMM 1441

Query: 226  TQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDDWACRHFRI--NYADEMQDVMH 283
            T+  E+ RVKCD YWP +     +G + V ++   E   +  R F +  N + E ++V  
Sbjct: 1442 TKLEERSRVKCDQYWP-SRGTETHGLVQVTLLDTVELATYCVRTFALYKNGSSEKREVRQ 1500

Query: 284  FNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQ 343
            F +TAWPDHGVP        L F+  V+       GPM++HCSAGVGRTG FI +D +L+
Sbjct: 1501 FQFTAWPDHGVP--EHPTPFLAFLRRVKTCNPPDAGPMVVHCSAGVGRTGCFIVIDAMLE 1558

Query: 344  HIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCV 381
             I+  + VDI G V+ MR+ R  MVQTE+QYIFIH  +
Sbjct: 1559 RIKHEKTVDIYGHVTLMRAQRNYMVQTEDQYIFIHDAL 1596



 Score =  191 bits (484), Expect = 1e-48
 Identities = 103/240 (42%), Positives = 144/240 (60%), Gaps = 9/240 (3%)

Query: 145  AADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLP 204
            +A+LP N+ KNR  NI+PY+ +RV L  +   EG+DYINA++I GY   + YIATQGPL 
Sbjct: 1650 SANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLA 1709

Query: 205  ETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDD 264
            ET  DFW+M+ +  S I+VMLT+  E  R KC  YWP  E    Y    V+ ++E     
Sbjct: 1710 ETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWP-AERSARYQYFVVDPMAEYNMPQ 1768

Query: 265  WACRHFRINYADEMQD--VMHFNYTAWPDHGVPTANAAESILQF---VHMVRQQATKSKG 319
            +  R F++  A + Q   V  F +T WP+ GVP   + E  + F   VH  ++Q  +  G
Sbjct: 1769 YILREFKVTDARDGQSRTVRQFQFTDWPEQGVP--KSGEGFIDFIGQVHKTKEQFGQD-G 1825

Query: 320  PMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQ 379
            P+ +HCSAGVGRTG FI L  +L+ +R    VDI   V  +R+ R +MVQTE+QY F ++
Sbjct: 1826 PISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDQYQFSYR 1885


>gi|18860892 protein tyrosine phosphatase, receptor type, D isoform 3
            precursor [Homo sapiens]
          Length = 1903

 Score =  223 bits (569), Expect = 2e-58
 Identities = 116/278 (41%), Positives = 169/278 (60%), Gaps = 6/278 (2%)

Query: 106  PVQLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDF 165
            P+ + +   +I+ +  + + KFS ++E +   G       ++L +N+ KNRY N++ YD 
Sbjct: 1327 PIPILELADHIERLKANDNLKFSQEYESIDP-GQQFTWEHSNLEVNKPKNRYANVIAYDH 1385

Query: 166  SRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVML 225
            SRV L ++    G+DY+NANYI GY     YIATQG LPET  DFW+M+ +Q+S  +VM+
Sbjct: 1386 SRVLLSAIEGIPGSDYVNANYIDGYRKQNAYIATQGSLPETFGDFWRMIWEQRSATVVMM 1445

Query: 226  TQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDDWACRHFRI--NYADEMQDVMH 283
            T+  E+ RVKCD YWP +     +G + V ++   E   +  R F +  N + E ++V  
Sbjct: 1446 TKLEERSRVKCDQYWP-SRGTETHGLVQVTLLDTVELATYCVRTFALYKNGSSEKREVRQ 1504

Query: 284  FNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQ 343
            F +TAWPDHGVP        L F+  V+       GPM++HCSAGVGRTG FI +D +L+
Sbjct: 1505 FQFTAWPDHGVP--EHPTPFLAFLRRVKTCNPPDAGPMVVHCSAGVGRTGCFIVIDAMLE 1562

Query: 344  HIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCV 381
             I+  + VDI G V+ MR+ R  MVQTE+QYIFIH  +
Sbjct: 1563 RIKHEKTVDIYGHVTLMRAQRNYMVQTEDQYIFIHDAL 1600



 Score =  191 bits (484), Expect = 1e-48
 Identities = 103/240 (42%), Positives = 144/240 (60%), Gaps = 9/240 (3%)

Query: 145  AADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLP 204
            +A+LP N+ KNR  NI+PY+ +RV L  +   EG+DYINA++I GY   + YIATQGPL 
Sbjct: 1654 SANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLA 1713

Query: 205  ETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDD 264
            ET  DFW+M+ +  S I+VMLT+  E  R KC  YWP  E    Y    V+ ++E     
Sbjct: 1714 ETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWP-AERSARYQYFVVDPMAEYNMPQ 1772

Query: 265  WACRHFRINYADEMQD--VMHFNYTAWPDHGVPTANAAESILQF---VHMVRQQATKSKG 319
            +  R F++  A + Q   V  F +T WP+ GVP   + E  + F   VH  ++Q  +  G
Sbjct: 1773 YILREFKVTDARDGQSRTVRQFQFTDWPEQGVP--KSGEGFIDFIGQVHKTKEQFGQD-G 1829

Query: 320  PMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQ 379
            P+ +HCSAGVGRTG FI L  +L+ +R    VDI   V  +R+ R +MVQTE+QY F ++
Sbjct: 1830 PISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDQYQFSYR 1889


>gi|18860894 protein tyrosine phosphatase, receptor type, D isoform 4
            precursor [Homo sapiens]
          Length = 1501

 Score =  223 bits (569), Expect = 2e-58
 Identities = 116/278 (41%), Positives = 169/278 (60%), Gaps = 6/278 (2%)

Query: 106  PVQLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDF 165
            P+ + +   +I+ +  + + KFS ++E +   G       ++L +N+ KNRY N++ YD 
Sbjct: 925  PIPILELADHIERLKANDNLKFSQEYESIDP-GQQFTWEHSNLEVNKPKNRYANVIAYDH 983

Query: 166  SRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVML 225
            SRV L ++    G+DY+NANYI GY     YIATQG LPET  DFW+M+ +Q+S  +VM+
Sbjct: 984  SRVLLSAIEGIPGSDYVNANYIDGYRKQNAYIATQGSLPETFGDFWRMIWEQRSATVVMM 1043

Query: 226  TQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDDWACRHFRI--NYADEMQDVMH 283
            T+  E+ RVKCD YWP +     +G + V ++   E   +  R F +  N + E ++V  
Sbjct: 1044 TKLEERSRVKCDQYWP-SRGTETHGLVQVTLLDTVELATYCVRTFALYKNGSSEKREVRQ 1102

Query: 284  FNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQ 343
            F +TAWPDHGVP        L F+  V+       GPM++HCSAGVGRTG FI +D +L+
Sbjct: 1103 FQFTAWPDHGVP--EHPTPFLAFLRRVKTCNPPDAGPMVVHCSAGVGRTGCFIVIDAMLE 1160

Query: 344  HIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCV 381
             I+  + VDI G V+ MR+ R  MVQTE+QYIFIH  +
Sbjct: 1161 RIKHEKTVDIYGHVTLMRAQRNYMVQTEDQYIFIHDAL 1198



 Score =  191 bits (484), Expect = 1e-48
 Identities = 103/240 (42%), Positives = 144/240 (60%), Gaps = 9/240 (3%)

Query: 145  AADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLP 204
            +A+LP N+ KNR  NI+PY+ +RV L  +   EG+DYINA++I GY   + YIATQGPL 
Sbjct: 1252 SANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLA 1311

Query: 205  ETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDD 264
            ET  DFW+M+ +  S I+VMLT+  E  R KC  YWP  E    Y    V+ ++E     
Sbjct: 1312 ETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWP-AERSARYQYFVVDPMAEYNMPQ 1370

Query: 265  WACRHFRINYADEMQD--VMHFNYTAWPDHGVPTANAAESILQF---VHMVRQQATKSKG 319
            +  R F++  A + Q   V  F +T WP+ GVP   + E  + F   VH  ++Q  +  G
Sbjct: 1371 YILREFKVTDARDGQSRTVRQFQFTDWPEQGVP--KSGEGFIDFIGQVHKTKEQFGQD-G 1427

Query: 320  PMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQ 379
            P+ +HCSAGVGRTG FI L  +L+ +R    VDI   V  +R+ R +MVQTE+QY F ++
Sbjct: 1428 PISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDQYQFSYR 1487


>gi|148539860 protein tyrosine phosphatase, receptor type, T isoform 2
            precursor [Homo sapiens]
          Length = 1441

 Score =  222 bits (566), Expect = 4e-58
 Identities = 118/277 (42%), Positives = 167/277 (60%), Gaps = 7/277 (2%)

Query: 107  VQLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDFS 166
            +++ D   +I  M +   Y F  ++E L   G       A    NR KNRY NI+ YD S
Sbjct: 869  IRVADLLQHITQMKRGQGYGFKEEYEALPE-GQTASWDTAKEDENRNKNRYGNIISYDHS 927

Query: 167  RVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLT 226
            RVRL+ ++ +  +DYINANYI GY+ P+ YIATQGP+ ET  DFW+M+ Q+ S  IVM+T
Sbjct: 928  RVRLLVLDGDPHSDYINANYIDGYHRPRHYIATQGPMQETVKDFWRMIWQENSASIVMVT 987

Query: 227  QCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDDWACRHFRINYA--DEMQDVMHF 284
               E  RVKC  YWP  ++   YGDI V +I  E   ++  R F +      E++++  F
Sbjct: 988  NLVEVGRVKCVRYWP--DDTEVYGDIKVTLIETEPLAEYVIRTFTVQKKGYHEIRELRLF 1045

Query: 285  NYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQH 344
            ++T+WPDHGVP    A  +L FV  V+       GP+++HCSAG GRTG FIA+D +L  
Sbjct: 1046 HFTSWPDHGVPC--YATGLLGFVRQVKFLNPPEAGPIVVHCSAGAGRTGCFIAIDTMLDM 1103

Query: 345  IRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCV 381
              +   VDI   V E+R+ R+++VQTEEQY+F+H  +
Sbjct: 1104 AENEGVVDIFNCVRELRAQRVNLVQTEEQYVFVHDAI 1140



 Score =  128 bits (321), Expect = 1e-29
 Identities = 78/239 (32%), Positives = 125/239 (52%), Gaps = 12/239 (5%)

Query: 148  LPLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETR 207
            LP N  KNR  ++LP D     L+S+ + E ++YINA  +  +  P  ++ TQ PLP T 
Sbjct: 1199 LPRNHDKNRSMDVLPLDRCLPFLISV-DGESSNYINAALMDSHKQPAAFVVTQHPLPNTV 1257

Query: 208  NDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDDWAC 267
             DFW++V       +VML + +  +   C  YWP  +    YG I VE +S +  +D   
Sbjct: 1258 ADFWRLVFDYNCSSVVMLNEMDTAQF--CMQYWP-EKTSGCYGPIQVEFVSADIDEDIIH 1314

Query: 268  RHFRINYADEMQD----VMHFNYTAWPDHGVPTANAAESILQFVHMV---RQQATKSKGP 320
            R FRI      QD    V H  Y  WP +   T  +  S+L+ V  +   ++Q    +G 
Sbjct: 1315 RIFRICNMARPQDGYRIVQHLQYIGWPAYR-DTPPSKRSLLKVVRRLEKWQEQYDGREGR 1373

Query: 321  MIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQ 379
             ++HC  G GR+GTF A+  + + I+    +D+  +V  +R+ + +MV+T EQY F+++
Sbjct: 1374 TVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFHIVKTLRNNKSNMVETLEQYKFVYE 1432


>gi|148539858 protein tyrosine phosphatase, receptor type, T isoform 1
            precursor [Homo sapiens]
          Length = 1460

 Score =  222 bits (566), Expect = 4e-58
 Identities = 118/277 (42%), Positives = 167/277 (60%), Gaps = 7/277 (2%)

Query: 107  VQLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDFS 166
            +++ D   +I  M +   Y F  ++E L   G       A    NR KNRY NI+ YD S
Sbjct: 888  IRVADLLQHITQMKRGQGYGFKEEYEALPE-GQTASWDTAKEDENRNKNRYGNIISYDHS 946

Query: 167  RVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLT 226
            RVRL+ ++ +  +DYINANYI GY+ P+ YIATQGP+ ET  DFW+M+ Q+ S  IVM+T
Sbjct: 947  RVRLLVLDGDPHSDYINANYIDGYHRPRHYIATQGPMQETVKDFWRMIWQENSASIVMVT 1006

Query: 227  QCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDDWACRHFRINYA--DEMQDVMHF 284
               E  RVKC  YWP  ++   YGDI V +I  E   ++  R F +      E++++  F
Sbjct: 1007 NLVEVGRVKCVRYWP--DDTEVYGDIKVTLIETEPLAEYVIRTFTVQKKGYHEIRELRLF 1064

Query: 285  NYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQH 344
            ++T+WPDHGVP    A  +L FV  V+       GP+++HCSAG GRTG FIA+D +L  
Sbjct: 1065 HFTSWPDHGVPC--YATGLLGFVRQVKFLNPPEAGPIVVHCSAGAGRTGCFIAIDTMLDM 1122

Query: 345  IRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCV 381
              +   VDI   V E+R+ R+++VQTEEQY+F+H  +
Sbjct: 1123 AENEGVVDIFNCVRELRAQRVNLVQTEEQYVFVHDAI 1159



 Score =  128 bits (321), Expect = 1e-29
 Identities = 78/239 (32%), Positives = 125/239 (52%), Gaps = 12/239 (5%)

Query: 148  LPLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETR 207
            LP N  KNR  ++LP D     L+S+ + E ++YINA  +  +  P  ++ TQ PLP T 
Sbjct: 1218 LPRNHDKNRSMDVLPLDRCLPFLISV-DGESSNYINAALMDSHKQPAAFVVTQHPLPNTV 1276

Query: 208  NDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDDWAC 267
             DFW++V       +VML + +  +   C  YWP  +    YG I VE +S +  +D   
Sbjct: 1277 ADFWRLVFDYNCSSVVMLNEMDTAQF--CMQYWP-EKTSGCYGPIQVEFVSADIDEDIIH 1333

Query: 268  RHFRINYADEMQD----VMHFNYTAWPDHGVPTANAAESILQFVHMV---RQQATKSKGP 320
            R FRI      QD    V H  Y  WP +   T  +  S+L+ V  +   ++Q    +G 
Sbjct: 1334 RIFRICNMARPQDGYRIVQHLQYIGWPAYR-DTPPSKRSLLKVVRRLEKWQEQYDGREGR 1392

Query: 321  MIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQ 379
             ++HC  G GR+GTF A+  + + I+    +D+  +V  +R+ + +MV+T EQY F+++
Sbjct: 1393 TVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFHIVKTLRNNKSNMVETLEQYKFVYE 1451


>gi|157419150 protein tyrosine phosphatase, receptor type, M isoform 2
            precursor [Homo sapiens]
          Length = 1452

 Score =  219 bits (558), Expect = 3e-57
 Identities = 117/277 (42%), Positives = 162/277 (58%), Gaps = 7/277 (2%)

Query: 107  VQLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDFS 166
            +++ D   +I  M     Y F  ++E     G   P  +A    NR KNRY NI+ YD S
Sbjct: 880  IRVADLLQHITQMKCAEGYGFKEEYESF-FEGQSAPWDSAKKDENRMKNRYGNIIAYDHS 938

Query: 167  RVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLT 226
            RVRL ++  +  +DYIN NYI GY+ P  YIATQGP+ ET  DFW+MV  + +  I+M+T
Sbjct: 939  RVRLQTIEGDTNSDYINGNYIDGYHRPNHYIATQGPMQETIYDFWRMVWHENTASIIMVT 998

Query: 227  QCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDDWACRHFRINY--ADEMQDVMHF 284
               E  RVKC  YWP  ++   Y DI V +I  E   ++  R F +      E++++  F
Sbjct: 999  NLVEVGRVKCCKYWP--DDTEIYKDIKVTLIETELLAEYVIRTFAVEKRGVHEIREIRQF 1056

Query: 285  NYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQH 344
            ++T WPDHGVP    A  +L FV  V+ ++  S GP+++HCSAG GRTG FI +D +L  
Sbjct: 1057 HFTGWPDHGVP--YHATGLLGFVRQVKSKSPPSAGPLVVHCSAGAGRTGCFIVIDIMLDM 1114

Query: 345  IRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCV 381
                  VDI   V E+RS R++MVQTEEQY+FIH  +
Sbjct: 1115 AEREGVVDIYNCVRELRSRRVNMVQTEEQYVFIHDAI 1151



 Score =  122 bits (306), Expect = 6e-28
 Identities = 79/240 (32%), Positives = 123/240 (51%), Gaps = 14/240 (5%)

Query: 148  LPLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETR 207
            LP N  KNR  +ILP D     L+++ + E ++YINA  +  Y  P  +I TQ PLP T 
Sbjct: 1210 LPRNHEKNRCMDILPPDRCLPFLITI-DGESSNYINAALMDSYKQPSAFIVTQHPLPNTV 1268

Query: 208  NDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPI-AYGDITVEMISEEEQDDWA 266
             DFW++VL      +VML   +  +   C  YWP  E  +  +G I VE +S + ++D  
Sbjct: 1269 KDFWRLVLDYHCTSVVMLNDVDPAQ--LCPQYWP--ENGVHRHGPIQVEFVSADLEEDII 1324

Query: 267  CRHFRINYADEMQD----VMHFNYTAWPDHGVPTANAAESILQFVHMV---RQQATKSKG 319
             R FRI  A   QD    V  F +  WP +   T  +  S L+ +  V   +++    +G
Sbjct: 1325 SRIFRIYNAARPQDGYRMVQQFQFLGWPMYR-DTPVSKRSFLKLIRQVDKWQEEYNGGEG 1383

Query: 320  PMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQ 379
              ++HC  G GR+GTF A+  + + +R    VD+   V  +R+ + +MV   +QY F ++
Sbjct: 1384 RTVVHCLNGGGRSGTFCAISIVCEMLRHQRTVDVFHAVKTLRNNKPNMVDLLDQYKFCYE 1443


>gi|157419152 protein tyrosine phosphatase, receptor type, M isoform 1
            precursor [Homo sapiens]
          Length = 1465

 Score =  219 bits (558), Expect = 3e-57
 Identities = 117/277 (42%), Positives = 162/277 (58%), Gaps = 7/277 (2%)

Query: 107  VQLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDFS 166
            +++ D   +I  M     Y F  ++E     G   P  +A    NR KNRY NI+ YD S
Sbjct: 893  IRVADLLQHITQMKCAEGYGFKEEYESF-FEGQSAPWDSAKKDENRMKNRYGNIIAYDHS 951

Query: 167  RVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLT 226
            RVRL ++  +  +DYIN NYI GY+ P  YIATQGP+ ET  DFW+MV  + +  I+M+T
Sbjct: 952  RVRLQTIEGDTNSDYINGNYIDGYHRPNHYIATQGPMQETIYDFWRMVWHENTASIIMVT 1011

Query: 227  QCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDDWACRHFRINY--ADEMQDVMHF 284
               E  RVKC  YWP  ++   Y DI V +I  E   ++  R F +      E++++  F
Sbjct: 1012 NLVEVGRVKCCKYWP--DDTEIYKDIKVTLIETELLAEYVIRTFAVEKRGVHEIREIRQF 1069

Query: 285  NYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQH 344
            ++T WPDHGVP    A  +L FV  V+ ++  S GP+++HCSAG GRTG FI +D +L  
Sbjct: 1070 HFTGWPDHGVP--YHATGLLGFVRQVKSKSPPSAGPLVVHCSAGAGRTGCFIVIDIMLDM 1127

Query: 345  IRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCV 381
                  VDI   V E+RS R++MVQTEEQY+FIH  +
Sbjct: 1128 AEREGVVDIYNCVRELRSRRVNMVQTEEQYVFIHDAI 1164



 Score =  122 bits (306), Expect = 6e-28
 Identities = 79/240 (32%), Positives = 123/240 (51%), Gaps = 14/240 (5%)

Query: 148  LPLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETR 207
            LP N  KNR  +ILP D     L+++ + E ++YINA  +  Y  P  +I TQ PLP T 
Sbjct: 1223 LPRNHEKNRCMDILPPDRCLPFLITI-DGESSNYINAALMDSYKQPSAFIVTQHPLPNTV 1281

Query: 208  NDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPI-AYGDITVEMISEEEQDDWA 266
             DFW++VL      +VML   +  +   C  YWP  E  +  +G I VE +S + ++D  
Sbjct: 1282 KDFWRLVLDYHCTSVVMLNDVDPAQ--LCPQYWP--ENGVHRHGPIQVEFVSADLEEDII 1337

Query: 267  CRHFRINYADEMQD----VMHFNYTAWPDHGVPTANAAESILQFVHMV---RQQATKSKG 319
             R FRI  A   QD    V  F +  WP +   T  +  S L+ +  V   +++    +G
Sbjct: 1338 SRIFRIYNAARPQDGYRMVQQFQFLGWPMYR-DTPVSKRSFLKLIRQVDKWQEEYNGGEG 1396

Query: 320  PMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQ 379
              ++HC  G GR+GTF A+  + + +R    VD+   V  +R+ + +MV   +QY F ++
Sbjct: 1397 RTVVHCLNGGGRSGTFCAISIVCEMLRHQRTVDVFHAVKTLRNNKPNMVDLLDQYKFCYE 1456


>gi|18641364 protein tyrosine phosphatase, receptor type, C isoform
           3 precursor [Homo sapiens]
          Length = 1256

 Score =  216 bits (549), Expect = 4e-56
 Identities = 111/280 (39%), Positives = 162/280 (57%), Gaps = 6/280 (2%)

Query: 106 PVQLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDF 165
           P+  D      K    D    F  +F+ +  +    P   A  P N+ KNRY +ILPYD+
Sbjct: 582 PIHADILLETYKRKIADEGRLFLAEFQSIPRVFSKFPIKEARKPFNQNKNRYVDILPYDY 641

Query: 166 SRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVML 225
           +RV L  +N + G++YINA+YI G+  P++YIA QGP  ET +DFW+M+ +QK+ +IVM+
Sbjct: 642 NRVELSEINGDAGSNYINASYIDGFKEPRKYIAAQGPRDETVDDFWRMIWEQKATVIVMV 701

Query: 226 TQCNEKRRVKCDHYWPFTEEPI-AYGDITVEMISEEEQDDWACRHFRINYADEM---QDV 281
           T+C E  R KC  YWP  EE   A+GD+ V++   +   D+  +   I    E    ++V
Sbjct: 702 TRCEEGNRNKCAEYWPSMEEGTRAFGDVVVKINQHKRCPDYIIQKLNIVNKKEKATGREV 761

Query: 282 MHFNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRL 341
            H  +T+WPDHGVP       +L+    V   +    GP+++HCSAGVGRTGT+I +D +
Sbjct: 762 THIQFTSWPDHGVP--EDPHLLLKLRRRVNAFSNFFSGPIVVHCSAGVGRTGTYIGIDAM 819

Query: 342 LQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCV 381
           L+ +     VD+ G V ++R  R  MVQ E QYI IHQ +
Sbjct: 820 LEGLEAENKVDVYGYVVKLRRQRCLMVQVEAQYILIHQAL 859



 Score =  140 bits (354), Expect = 2e-33
 Identities = 87/260 (33%), Positives = 129/260 (49%), Gaps = 31/260 (11%)

Query: 151  NRCKNRYTNILPYDFSRVRLV-------------------SMNEEEGADYINANYIPGYN 191
            N+ KNR +N++PYD++RV L                      + EE + YINA++I  Y 
Sbjct: 918  NKSKNRNSNVIPYDYNRVPLKHELEMSKESEHDSDESSDDDSDSEEPSKYINASFIMSYW 977

Query: 192  SPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGD 251
             P+  IA QGPL ET  DFW+M+ Q+K ++IVMLT+     +  C  YW   E    YGD
Sbjct: 978  KPEVMIAAQGPLKETIGDFWQMIFQRKVKVIVMLTELKHGDQEICAQYW--GEGKQTYGD 1035

Query: 252  ITVEMISEEEQDDWACRHFRINYA--DEMQDVMHFNYTAWPDHGVPT-ANAAESILQFVH 308
            I V++   ++   +  R F + ++   + + V  + YT W    +P       S++Q V 
Sbjct: 1036 IEVDLKDTDKSSTYTLRVFELRHSKRKDSRTVYQYQYTNWSVEQLPAEPKELISMIQVVK 1095

Query: 309  MVRQQATKSKG-------PMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMR 361
                Q   S+G       P++IHC  G  +TG F AL  LL+     E VDI  +V  +R
Sbjct: 1096 QKLPQKNSSEGNKHHKSTPLLIHCRDGSQQTGIFCALLNLLESAETEEVVDIFQVVKALR 1155

Query: 362  SYRMSMVQTEEQYIFIHQCV 381
              R  MV T EQY F++  +
Sbjct: 1156 KARPGMVSTFEQYQFLYDVI 1175


>gi|18641347 protein tyrosine phosphatase, receptor type, C isoform
           1 precursor [Homo sapiens]
          Length = 1304

 Score =  216 bits (549), Expect = 4e-56
 Identities = 111/280 (39%), Positives = 162/280 (57%), Gaps = 6/280 (2%)

Query: 106 PVQLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDF 165
           P+  D      K    D    F  +F+ +  +    P   A  P N+ KNRY +ILPYD+
Sbjct: 630 PIHADILLETYKRKIADEGRLFLAEFQSIPRVFSKFPIKEARKPFNQNKNRYVDILPYDY 689

Query: 166 SRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVML 225
           +RV L  +N + G++YINA+YI G+  P++YIA QGP  ET +DFW+M+ +QK+ +IVM+
Sbjct: 690 NRVELSEINGDAGSNYINASYIDGFKEPRKYIAAQGPRDETVDDFWRMIWEQKATVIVMV 749

Query: 226 TQCNEKRRVKCDHYWPFTEEPI-AYGDITVEMISEEEQDDWACRHFRINYADEM---QDV 281
           T+C E  R KC  YWP  EE   A+GD+ V++   +   D+  +   I    E    ++V
Sbjct: 750 TRCEEGNRNKCAEYWPSMEEGTRAFGDVVVKINQHKRCPDYIIQKLNIVNKKEKATGREV 809

Query: 282 MHFNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRL 341
            H  +T+WPDHGVP       +L+    V   +    GP+++HCSAGVGRTGT+I +D +
Sbjct: 810 THIQFTSWPDHGVP--EDPHLLLKLRRRVNAFSNFFSGPIVVHCSAGVGRTGTYIGIDAM 867

Query: 342 LQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCV 381
           L+ +     VD+ G V ++R  R  MVQ E QYI IHQ +
Sbjct: 868 LEGLEAENKVDVYGYVVKLRRQRCLMVQVEAQYILIHQAL 907



 Score =  140 bits (354), Expect = 2e-33
 Identities = 87/260 (33%), Positives = 129/260 (49%), Gaps = 31/260 (11%)

Query: 151  NRCKNRYTNILPYDFSRVRLV-------------------SMNEEEGADYINANYIPGYN 191
            N+ KNR +N++PYD++RV L                      + EE + YINA++I  Y 
Sbjct: 966  NKSKNRNSNVIPYDYNRVPLKHELEMSKESEHDSDESSDDDSDSEEPSKYINASFIMSYW 1025

Query: 192  SPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGD 251
             P+  IA QGPL ET  DFW+M+ Q+K ++IVMLT+     +  C  YW   E    YGD
Sbjct: 1026 KPEVMIAAQGPLKETIGDFWQMIFQRKVKVIVMLTELKHGDQEICAQYW--GEGKQTYGD 1083

Query: 252  ITVEMISEEEQDDWACRHFRINYA--DEMQDVMHFNYTAWPDHGVPT-ANAAESILQFVH 308
            I V++   ++   +  R F + ++   + + V  + YT W    +P       S++Q V 
Sbjct: 1084 IEVDLKDTDKSSTYTLRVFELRHSKRKDSRTVYQYQYTNWSVEQLPAEPKELISMIQVVK 1143

Query: 309  MVRQQATKSKG-------PMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMR 361
                Q   S+G       P++IHC  G  +TG F AL  LL+     E VDI  +V  +R
Sbjct: 1144 QKLPQKNSSEGNKHHKSTPLLIHCRDGSQQTGIFCALLNLLESAETEEVVDIFQVVKALR 1203

Query: 362  SYRMSMVQTEEQYIFIHQCV 381
              R  MV T EQY F++  +
Sbjct: 1204 KARPGMVSTFEQYQFLYDVI 1223


>gi|18641362 protein tyrosine phosphatase, receptor type, C isoform
           2 precursor [Homo sapiens]
          Length = 1143

 Score =  216 bits (549), Expect = 4e-56
 Identities = 111/280 (39%), Positives = 162/280 (57%), Gaps = 6/280 (2%)

Query: 106 PVQLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDF 165
           P+  D      K    D    F  +F+ +  +    P   A  P N+ KNRY +ILPYD+
Sbjct: 469 PIHADILLETYKRKIADEGRLFLAEFQSIPRVFSKFPIKEARKPFNQNKNRYVDILPYDY 528

Query: 166 SRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVML 225
           +RV L  +N + G++YINA+YI G+  P++YIA QGP  ET +DFW+M+ +QK+ +IVM+
Sbjct: 529 NRVELSEINGDAGSNYINASYIDGFKEPRKYIAAQGPRDETVDDFWRMIWEQKATVIVMV 588

Query: 226 TQCNEKRRVKCDHYWPFTEEPI-AYGDITVEMISEEEQDDWACRHFRINYADEM---QDV 281
           T+C E  R KC  YWP  EE   A+GD+ V++   +   D+  +   I    E    ++V
Sbjct: 589 TRCEEGNRNKCAEYWPSMEEGTRAFGDVVVKINQHKRCPDYIIQKLNIVNKKEKATGREV 648

Query: 282 MHFNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRL 341
            H  +T+WPDHGVP       +L+    V   +    GP+++HCSAGVGRTGT+I +D +
Sbjct: 649 THIQFTSWPDHGVP--EDPHLLLKLRRRVNAFSNFFSGPIVVHCSAGVGRTGTYIGIDAM 706

Query: 342 LQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCV 381
           L+ +     VD+ G V ++R  R  MVQ E QYI IHQ +
Sbjct: 707 LEGLEAENKVDVYGYVVKLRRQRCLMVQVEAQYILIHQAL 746



 Score =  140 bits (354), Expect = 2e-33
 Identities = 87/260 (33%), Positives = 129/260 (49%), Gaps = 31/260 (11%)

Query: 151  NRCKNRYTNILPYDFSRVRLV-------------------SMNEEEGADYINANYIPGYN 191
            N+ KNR +N++PYD++RV L                      + EE + YINA++I  Y 
Sbjct: 805  NKSKNRNSNVIPYDYNRVPLKHELEMSKESEHDSDESSDDDSDSEEPSKYINASFIMSYW 864

Query: 192  SPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGD 251
             P+  IA QGPL ET  DFW+M+ Q+K ++IVMLT+     +  C  YW   E    YGD
Sbjct: 865  KPEVMIAAQGPLKETIGDFWQMIFQRKVKVIVMLTELKHGDQEICAQYW--GEGKQTYGD 922

Query: 252  ITVEMISEEEQDDWACRHFRINYA--DEMQDVMHFNYTAWPDHGVPT-ANAAESILQFVH 308
            I V++   ++   +  R F + ++   + + V  + YT W    +P       S++Q V 
Sbjct: 923  IEVDLKDTDKSSTYTLRVFELRHSKRKDSRTVYQYQYTNWSVEQLPAEPKELISMIQVVK 982

Query: 309  MVRQQATKSKG-------PMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMR 361
                Q   S+G       P++IHC  G  +TG F AL  LL+     E VDI  +V  +R
Sbjct: 983  QKLPQKNSSEGNKHHKSTPLLIHCRDGSQQTGIFCALLNLLESAETEEVVDIFQVVKALR 1042

Query: 362  SYRMSMVQTEEQYIFIHQCV 381
              R  MV T EQY F++  +
Sbjct: 1043 KARPGMVSTFEQYQFLYDVI 1062


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.324    0.137    0.425 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,742,662
Number of Sequences: 37866
Number of extensions: 627475
Number of successful extensions: 2320
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 113
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 1827
Number of HSP's gapped (non-prelim): 174
length of query: 405
length of database: 18,247,518
effective HSP length: 105
effective length of query: 300
effective length of database: 14,271,588
effective search space: 4281476400
effective search space used: 4281476400
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.5 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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