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Search of human proteins with 6912682
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|6912682 spondin 2, extracellular matrix protein [Homo
sapiens]
(331 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|190341087 spondin 2, extracellular matrix protein [Homo sapiens] 682 0.0
gi|6912682 spondin 2, extracellular matrix protein [Homo sapiens] 682 0.0
gi|110347423 spondin 1, extracellular matrix protein [Homo sapiens] 173 2e-43
gi|122937257 thrombospondin, type I, domain containing 7B [Homo ... 59 8e-09
gi|150170672 thrombospondin, type I, domain containing 7A [Homo ... 55 7e-08
gi|209969800 RPE-spondin [Homo sapiens] 49 8e-06
gi|134031945 SCO-spondin [Homo sapiens] 43 4e-04
gi|84490388 R-spondin1 [Homo sapiens] 42 8e-04
gi|18490982 R-spondin 3 [Homo sapiens] 41 0.002
gi|222446611 R-spondin family, member 2 [Homo sapiens] 40 0.002
gi|4557391 complement component 8, beta polypeptide preproprotei... 38 0.011
gi|111118994 brain-specific angiogenesis inhibitor 1 precursor [... 38 0.011
gi|145699139 cartilage intermediate layer protein 2 [Homo sapiens] 37 0.024
gi|192449445 cartilage intermediate layer protein [Homo sapiens] 36 0.042
gi|115387099 brain-specific angiogenesis inhibitor 2 [Homo sapiens] 35 0.071
gi|118572606 hemicentin 1 [Homo sapiens] 35 0.093
gi|209977117 unc-5 homolog D [Homo sapiens] 35 0.12
gi|87116683 proline/serine-rich coiled-coil 2 [Homo sapiens] 34 0.21
gi|4505737 complement factor properdin precursor [Homo sapiens] 33 0.35
gi|4502359 brain-specific angiogenesis inhibitor 3 [Homo sapiens] 33 0.35
gi|223671861 complement factor properdin precursor [Homo sapiens] 33 0.35
gi|4502511 complement component 9 precursor [Homo sapiens] 33 0.46
gi|158187511 T-box 22 isoform 2 [Homo sapiens] 33 0.46
gi|158187509 T-box 22 isoform 1 [Homo sapiens] 33 0.46
gi|18375603 T-box 22 isoform 1 [Homo sapiens] 33 0.46
gi|122937388 MAX gene associated [Homo sapiens] 33 0.46
gi|16933525 unc5C [Homo sapiens] 32 0.78
gi|110611170 ADAM metallopeptidase with thrombospondin type 1 mo... 32 0.78
gi|40317626 thrombospondin 1 precursor [Homo sapiens] 32 1.0
gi|14790190 spen homolog, transcriptional regulator [Homo sapiens] 32 1.0
>gi|190341087 spondin 2, extracellular matrix protein [Homo sapiens]
Length = 331
Score = 682 bits (1759), Expect = 0.0
Identities = 331/331 (100%), Positives = 331/331 (100%)
Query: 1 MENPSPAAALGKALCALLLATLGAAGQPLGGESICSARAPAKYSITFTGKWSQTAFPKQY 60
MENPSPAAALGKALCALLLATLGAAGQPLGGESICSARAPAKYSITFTGKWSQTAFPKQY
Sbjct: 1 MENPSPAAALGKALCALLLATLGAAGQPLGGESICSARAPAKYSITFTGKWSQTAFPKQY 60
Query: 61 PLFRPPAQWSSLLGAAHSSDYSMWRKNQYVSNGLRDFAERGEAWALMKEIEAAGEALQSV 120
PLFRPPAQWSSLLGAAHSSDYSMWRKNQYVSNGLRDFAERGEAWALMKEIEAAGEALQSV
Sbjct: 61 PLFRPPAQWSSLLGAAHSSDYSMWRKNQYVSNGLRDFAERGEAWALMKEIEAAGEALQSV 120
Query: 121 HAVFSAPAVPSGTGQTSAELEVQRRHSLVSFVVRIVPSPDWFVGVDSLDLCDGDRWREQA 180
HAVFSAPAVPSGTGQTSAELEVQRRHSLVSFVVRIVPSPDWFVGVDSLDLCDGDRWREQA
Sbjct: 121 HAVFSAPAVPSGTGQTSAELEVQRRHSLVSFVVRIVPSPDWFVGVDSLDLCDGDRWREQA 180
Query: 181 ALDLYPYDAGTDSGFTFSSPNFATIPQDTVTEITSSSPSHPANSFYYPRLKALPPIARVT 240
ALDLYPYDAGTDSGFTFSSPNFATIPQDTVTEITSSSPSHPANSFYYPRLKALPPIARVT
Sbjct: 181 ALDLYPYDAGTDSGFTFSSPNFATIPQDTVTEITSSSPSHPANSFYYPRLKALPPIARVT 240
Query: 241 LVRLRQSPRAFIPPAPVLPSRDNEIVDSASVPETPLDCEVSLWSSWGLCGGHCGRLGTKS 300
LVRLRQSPRAFIPPAPVLPSRDNEIVDSASVPETPLDCEVSLWSSWGLCGGHCGRLGTKS
Sbjct: 241 LVRLRQSPRAFIPPAPVLPSRDNEIVDSASVPETPLDCEVSLWSSWGLCGGHCGRLGTKS 300
Query: 301 RTRYVRVQPANNGSPCPELEEEAECVPDNCV 331
RTRYVRVQPANNGSPCPELEEEAECVPDNCV
Sbjct: 301 RTRYVRVQPANNGSPCPELEEEAECVPDNCV 331
>gi|6912682 spondin 2, extracellular matrix protein [Homo sapiens]
Length = 331
Score = 682 bits (1759), Expect = 0.0
Identities = 331/331 (100%), Positives = 331/331 (100%)
Query: 1 MENPSPAAALGKALCALLLATLGAAGQPLGGESICSARAPAKYSITFTGKWSQTAFPKQY 60
MENPSPAAALGKALCALLLATLGAAGQPLGGESICSARAPAKYSITFTGKWSQTAFPKQY
Sbjct: 1 MENPSPAAALGKALCALLLATLGAAGQPLGGESICSARAPAKYSITFTGKWSQTAFPKQY 60
Query: 61 PLFRPPAQWSSLLGAAHSSDYSMWRKNQYVSNGLRDFAERGEAWALMKEIEAAGEALQSV 120
PLFRPPAQWSSLLGAAHSSDYSMWRKNQYVSNGLRDFAERGEAWALMKEIEAAGEALQSV
Sbjct: 61 PLFRPPAQWSSLLGAAHSSDYSMWRKNQYVSNGLRDFAERGEAWALMKEIEAAGEALQSV 120
Query: 121 HAVFSAPAVPSGTGQTSAELEVQRRHSLVSFVVRIVPSPDWFVGVDSLDLCDGDRWREQA 180
HAVFSAPAVPSGTGQTSAELEVQRRHSLVSFVVRIVPSPDWFVGVDSLDLCDGDRWREQA
Sbjct: 121 HAVFSAPAVPSGTGQTSAELEVQRRHSLVSFVVRIVPSPDWFVGVDSLDLCDGDRWREQA 180
Query: 181 ALDLYPYDAGTDSGFTFSSPNFATIPQDTVTEITSSSPSHPANSFYYPRLKALPPIARVT 240
ALDLYPYDAGTDSGFTFSSPNFATIPQDTVTEITSSSPSHPANSFYYPRLKALPPIARVT
Sbjct: 181 ALDLYPYDAGTDSGFTFSSPNFATIPQDTVTEITSSSPSHPANSFYYPRLKALPPIARVT 240
Query: 241 LVRLRQSPRAFIPPAPVLPSRDNEIVDSASVPETPLDCEVSLWSSWGLCGGHCGRLGTKS 300
LVRLRQSPRAFIPPAPVLPSRDNEIVDSASVPETPLDCEVSLWSSWGLCGGHCGRLGTKS
Sbjct: 241 LVRLRQSPRAFIPPAPVLPSRDNEIVDSASVPETPLDCEVSLWSSWGLCGGHCGRLGTKS 300
Query: 301 RTRYVRVQPANNGSPCPELEEEAECVPDNCV 331
RTRYVRVQPANNGSPCPELEEEAECVPDNCV
Sbjct: 301 RTRYVRVQPANNGSPCPELEEEAECVPDNCV 331
>gi|110347423 spondin 1, extracellular matrix protein [Homo sapiens]
Length = 807
Score = 173 bits (439), Expect = 2e-43
Identities = 113/331 (34%), Positives = 164/331 (49%), Gaps = 21/331 (6%)
Query: 9 ALGKALCALLLATLGAAGQPLGGESICSARAPAKYSITFTGKWSQTAFPKQYPLFRPPAQ 68
+L K LC G +P+ C A AKY +TF G WS+ PK YP R
Sbjct: 176 SLTKKLCEQDSTFDGVTDKPILD---CCACGTAKYRLTFYGNWSEKTHPKDYP--RRANH 230
Query: 69 WSSLLGAAHSSDYSMWRKNQYVSNGLRDFAERGEAWALMKEI-EAAGEALQSVHAVFSAP 127
WS+++G +HS +Y +W Y S G++ AE G + +EI + + E L + A P
Sbjct: 231 WSAIIGGSHSKNYVLWEYGGYASEGVKQVAELGSPVKMEEEIRQQSDEVLTVIKAKAQWP 290
Query: 128 AVP--SGTGQTSAELEVQRRHSLVSFVVRIVPSPDWFVGVDSLDLCDGD-RWREQAALDL 184
A + SAE V R L+SF+ + PSPDW VG+ + DLC + W ++ DL
Sbjct: 291 AWQPLNVRAAPSAEFSVDRTRHLMSFLTMMGPSPDWNVGLSAEDLCTKECGWVQKVVQDL 350
Query: 185 YPYDAGTDSGFTFSSPNFATIPQDTVTEITSSSPSHPANSFYYPRLKALPPIARVTLVRL 244
P+DAGTDSG T+ SPN TIPQ+ + +TS HP + FY P ++ +ARV + R+
Sbjct: 351 IPWDAGTDSGVTYESPNKPTIPQEKIRPLTSL--DHPQSPFYDPEGGSITQVARVVIERI 408
Query: 245 -RQSPRAFIPPAPVLPSRDNEIVDSA----SVPETPLDCEVSLWSSWGLCGGHCGRLGTK 299
R+ + I P V D+ + D A +TP C S WS W C G +
Sbjct: 409 ARKGEQCNIVPDNV----DDIVADLAPEEKDEDDTPETCIYSNWSPWSACSSSTCDKGKR 464
Query: 300 SRTRYVRVQPANNGSPCPELEEEAECVPDNC 330
R R ++ Q + PCP+ ++ C+ C
Sbjct: 465 MRQRMLKAQ-LDLSVPCPDTQDFQPCMGPGC 494
Score = 63.9 bits (154), Expect = 2e-10
Identities = 27/72 (37%), Positives = 42/72 (58%), Gaps = 1/72 (1%)
Query: 260 SRDNEIVDSASVPETPLDCEVSLWSSWGLCGGHCGRLGTKSRTRYVRVQPANNGSPCPEL 319
+ D E V+ +PE P+DCE++ WS W C CG+ G RTR ++++P G+PCPE
Sbjct: 651 NEDLEQVEKCMLPECPIDCELTEWSQWSECNKSCGK-GHVIRTRMIQMEPQFGGAPCPET 709
Query: 320 EEEAECVPDNCV 331
+ +C C+
Sbjct: 710 VQRKKCRIRKCL 721
Score = 40.0 bits (92), Expect = 0.003
Identities = 23/61 (37%), Positives = 31/61 (50%), Gaps = 9/61 (14%)
Query: 278 CEVSLWSSWGLCGGHCGRLGTKSRTRYVRVQPANNGSPCPELEEEA-------ECVPDNC 330
C +S W +W C CG +G +SR RYV+ P +GS C EE EC P +C
Sbjct: 502 CTMSEWITWSPCSISCG-MGMRSRERYVKQFP-EDGSVCTLPTEETEKCTVNEECSPSSC 559
Query: 331 V 331
+
Sbjct: 560 L 560
Score = 39.3 bits (90), Expect = 0.005
Identities = 20/58 (34%), Positives = 30/58 (51%), Gaps = 3/58 (5%)
Query: 274 TPLDCEVSLWSSWGLCGGHCGRLGTKSRTRYVRVQPANNGSPCPELEEEAE-CVPDNC 330
+P C ++ W W C CG +G K R R +++ PA +GS C +AE C+ C
Sbjct: 555 SPSSCLMTEWGEWDECSATCG-MGMKKRHRMIKMNPA-DGSMCKAETSQAEKCMMPEC 610
Score = 31.6 bits (70), Expect = 1.0
Identities = 17/55 (30%), Positives = 28/55 (50%), Gaps = 2/55 (3%)
Query: 276 LDCEVSLWSSWGLCGGHCGRLGTKSRTRYVRVQPANNGSPCPELEEEAECVPDNC 330
+ C +S WS W C CG+ G ++R R ++ A G +LE+ +C+ C
Sbjct: 613 IPCLLSPWSEWSDCSVTCGK-GMRTRQRMLK-SLAELGDCNEDLEQVEKCMLPEC 665
>gi|122937257 thrombospondin, type I, domain containing 7B [Homo
sapiens]
Length = 1577
Score = 58.5 bits (140), Expect = 8e-09
Identities = 26/68 (38%), Positives = 40/68 (58%), Gaps = 2/68 (2%)
Query: 253 PPAPVLPSRDNEIVDSASVPETPLDCEVSLWSSWGLCGGHCGRLGTKSRTRYVRVQPANN 312
P P S I + +P P DC++S WSSWG C CG +G + R+++++ +P N
Sbjct: 946 PVDPSFCSSSGYIQEKCVIP-CPFDCKLSDWSSWGSCSSSCG-IGVRIRSKWLKEKPYNG 1003
Query: 313 GSPCPELE 320
G PCP+L+
Sbjct: 1004 GRPCPKLD 1011
Score = 48.9 bits (115), Expect = 6e-06
Identities = 22/59 (37%), Positives = 32/59 (54%), Gaps = 1/59 (1%)
Query: 273 ETPLDCEVSLWSSWGLCGGHCGRLGTKSRTRYVRVQPANNGSPCP-ELEEEAECVPDNC 330
E ++C++S W++W C CG G SRTR++ + G PCP EL +E C C
Sbjct: 1214 ECVVNCQLSGWTAWTECSQTCGHGGRMSRTRFIIMPTQGEGRPCPTELTQEKTCPVTPC 1272
Score = 48.5 bits (114), Expect = 8e-06
Identities = 25/56 (44%), Positives = 30/56 (53%), Gaps = 4/56 (7%)
Query: 275 PLDCEVSLWSSWGLCGGHC--GRL--GTKSRTRYVRVQPANNGSPCPELEEEAECV 326
P DCE S WSSW C C G L G +SR+R V+ G CPEL E+ C+
Sbjct: 303 PKDCETSQWSSWSPCSKTCRSGSLLPGFRSRSRNVKHMAIGGGKECPELLEKEACI 358
Score = 43.9 bits (102), Expect = 2e-04
Identities = 30/84 (35%), Positives = 40/84 (47%), Gaps = 13/84 (15%)
Query: 252 IPPAPVLPSRDNEIVDSASVPETPLDCEVSLWSSWGLC-GGHC----GRLGTKSRTRYVR 306
+ PAP LPS+ I S DC VS WS+WGLC +C G+ G ++R R+V
Sbjct: 436 VGPAP-LPSQLCNIPCST-------DCIVSSWSAWGLCIHENCHDPQGKKGFRTRQRHVL 487
Query: 307 VQPANNGSPCPELEEEAECVPDNC 330
++ CP L E C C
Sbjct: 488 MESTGPAGHCPHLVESVPCEDPMC 511
Score = 40.0 bits (92), Expect = 0.003
Identities = 26/80 (32%), Positives = 38/80 (47%), Gaps = 8/80 (10%)
Query: 258 LPSRDNEIVDSASVPETPLDCEVSLWSSWGLCGGHC--GR----LGTKSRTRYVRVQPAN 311
+P +D+ + SVP P DC ++ WS W C C GR +G +SR+R +Q
Sbjct: 1323 MPFQDSILKQLCSVP-CPGDCHLTEWSEWSTCELTCIDGRSFETVGRQSRSRTFIIQSFE 1381
Query: 312 NGSPCP-ELEEEAECVPDNC 330
N CP ++ E C C
Sbjct: 1382 NQDSCPQQVLETRPCTGGKC 1401
Score = 39.3 bits (90), Expect = 0.005
Identities = 24/84 (28%), Positives = 35/84 (41%), Gaps = 12/84 (14%)
Query: 254 PAPVLPSRDNEIVDSASVPETPLDCEVSLWSSWGLCGGHCGRL---GTKSRTRYVRVQPA 310
P P P R S +P +DC +S W+ W C C G ++R+R +
Sbjct: 553 PVPPPPERK-----SCEIP-CRMDCVLSEWTEWSSCSQSCSNKNSDGKQTRSRTILALAG 606
Query: 311 NNGSPCP---ELEEEAECVPDNCV 331
G PCP L+E C +C+
Sbjct: 607 EGGKPCPPSQALQEHRLCNDHSCM 630
Score = 38.9 bits (89), Expect = 0.006
Identities = 23/65 (35%), Positives = 29/65 (44%), Gaps = 2/65 (3%)
Query: 267 DSASVPETPLDCEVSLWSSWGLCGGHCGRLGTKSRTRYVRVQPANNGSPCPELEEEAEC- 325
+ A + P DC VS + W C CG+ + RTR V P G CP L E C
Sbjct: 138 EQACLIPCPRDCVVSEFLPWSNCSKGCGK-KLQHRTRAVIAPPLFGGLQCPNLTESRACD 196
Query: 326 VPDNC 330
P +C
Sbjct: 197 APISC 201
Score = 34.7 bits (78), Expect = 0.12
Identities = 22/53 (41%), Positives = 27/53 (50%), Gaps = 4/53 (7%)
Query: 277 DCEVSLWSSWGLCGGHC--GRLGTK-SRTRYVRVQPANNGSPCPE-LEEEAEC 325
DC V+ +S W C C G K SR R + + AN G CP+ L EE EC
Sbjct: 706 DCIVTAFSEWTPCPRMCQAGNATVKQSRYRIIIQEAANGGQECPDTLYEEREC 758
Score = 33.1 bits (74), Expect = 0.35
Identities = 17/57 (29%), Positives = 28/57 (49%), Gaps = 2/57 (3%)
Query: 275 PLDCEVSLWSSWGLCGGHCGRLGTKSRTRYVRVQPANNGSPCPELEEEAEC-VPDNC 330
P +C +S W W C C + RTR++ ++P+ N C E + C + +NC
Sbjct: 1096 PNECVMSEWGLWSKCPQSCDPHTMQRRTRHL-LRPSLNSRTCAEDSQVQPCLLNENC 1151
>gi|150170672 thrombospondin, type I, domain containing 7A [Homo
sapiens]
Length = 1657
Score = 55.5 bits (132), Expect = 7e-08
Identities = 22/55 (40%), Positives = 35/55 (63%), Gaps = 1/55 (1%)
Query: 266 VDSASVPETPLDCEVSLWSSWGLCGGHCGRLGTKSRTRYVRVQPANNGSPCPELE 320
++ A + P DC++S WS+W C CG G K R++++R +P N G PCP+L+
Sbjct: 1024 IEEACIIPCPSDCKLSEWSNWSRCSKSCGS-GVKVRSKWLREKPYNGGRPCPKLD 1077
Score = 47.0 bits (110), Expect = 2e-05
Identities = 20/62 (32%), Positives = 34/62 (54%)
Query: 266 VDSASVPETPLDCEVSLWSSWGLCGGHCGRLGTKSRTRYVRVQPANNGSPCPELEEEAEC 325
++++ + E P++C++S WS W C CG G R R V +G PCP L ++++
Sbjct: 1275 MNTSCMVECPVNCQLSDWSPWSECSQTCGLTGKMIRRRTVTQPFQGDGRPCPSLMDQSKP 1334
Query: 326 VP 327
P
Sbjct: 1335 CP 1336
Score = 46.6 bits (109), Expect = 3e-05
Identities = 21/54 (38%), Positives = 29/54 (53%), Gaps = 4/54 (7%)
Query: 277 DCEVSLWSSWGLCGGHCGRL----GTKSRTRYVRVQPANNGSPCPELEEEAECV 326
+C+VS WS W C C + GT+ RTR +R P + CPE EE+ C+
Sbjct: 360 ECQVSEWSEWSPCSKTCHDMVSPAGTRVRTRTIRQFPIGSEKECPEFEEKEPCL 413
Score = 44.3 bits (103), Expect = 2e-04
Identities = 24/66 (36%), Positives = 32/66 (48%), Gaps = 1/66 (1%)
Query: 265 IVDSASVPETPLDCEVSLWSSWGLCGGHCGRLGTKSRTRYVRVQPANNGSPCPELEEEAE 324
+++ A + DC VS +S+W C CG G + RTR+V P GS CP L E
Sbjct: 182 LLEQACLIPCQQDCIVSEFSAWSECSKTCGS-GLQHRTRHVVAPPQFGGSGCPNLTEFQV 240
Query: 325 CVPDNC 330
C C
Sbjct: 241 CQSSPC 246
Score = 40.4 bits (93), Expect = 0.002
Identities = 24/81 (29%), Positives = 35/81 (43%), Gaps = 7/81 (8%)
Query: 257 VLPSRDNEIVDSASVPETPLDCEVSLWSSWGLC------GGHCGRLGTKSRTRYVRVQPA 310
++ N +++ + P DC + WSSW LC G G G + R+R V +Q
Sbjct: 1394 IIDGNKNMVLEESCSQPCPGDCYLKDWSSWSLCQLTCVNGEDLGFGGIQVRSRPVIIQEL 1453
Query: 311 NNGSPCPE-LEEEAECVPDNC 330
N CPE + E C C
Sbjct: 1454 ENQHLCPEQMLETKSCYDGQC 1474
Score = 38.9 bits (89), Expect = 0.006
Identities = 22/64 (34%), Positives = 27/64 (42%), Gaps = 8/64 (12%)
Query: 275 PLDCEVSLWSSWG-----LCGGHCGRLGTKSRTRYVRVQPANNG---SPCPELEEEAECV 326
P +CEVS WS+WG C G+ G K R R + +P CP L E C
Sbjct: 510 PTECEVSPWSAWGPCTYENCNDQQGKKGFKLRKRRITNEPTGGSGVTGNCPHLLEAIPCE 569
Query: 327 PDNC 330
C
Sbjct: 570 EPAC 573
Score = 38.5 bits (88), Expect = 0.008
Identities = 19/57 (33%), Positives = 26/57 (45%), Gaps = 1/57 (1%)
Query: 275 PLDCEVSLWSSWGLCGGHCGRLGTKSRTRYVRVQPANNGSPCPELEEEAEC-VPDNC 330
P DC +S W W C C + + R+ QPA+ G CP E+ C + NC
Sbjct: 1163 PEDCVISEWGPWTQCVLPCNQSSFRQRSADPIRQPADEGRSCPNAVEKEPCNLNKNC 1219
Score = 33.5 bits (75), Expect = 0.27
Identities = 11/26 (42%), Positives = 17/26 (65%)
Query: 277 DCEVSLWSSWGLCGGHCGRLGTKSRT 302
DC+++ WS + C G CG + T+ RT
Sbjct: 906 DCQLTSWSKFSSCNGDCGAVRTRKRT 931
Score = 33.1 bits (74), Expect = 0.35
Identities = 21/60 (35%), Positives = 27/60 (45%), Gaps = 6/60 (10%)
Query: 277 DCEVSLWSSWGLCGGHC----GRLGTKSRTRYVRVQPANNGSPC--PELEEEAECVPDNC 330
DC V+ +S W C C + +SR R + PAN G C P EE+A P C
Sbjct: 771 DCIVTPYSDWTSCPSSCKEGDSSIRKQSRHRVIIQLPANGGRDCTDPLYEEKACEAPQAC 830
Score = 30.4 bits (67), Expect = 2.3
Identities = 19/63 (30%), Positives = 24/63 (38%), Gaps = 7/63 (11%)
Query: 275 PLDCEVSLWSSWGLCGGHCG---RLGTKSRTRYVRVQPANNGS-PCPE---LEEEAECVP 327
P DC +S WS+W C C G + R R + G CP L+E C
Sbjct: 632 PKDCVLSTWSTWSSCSHTCSGKTTEGKQIRARSILAYAGEEGGIRCPNSSALQEVRSCNE 691
Query: 328 DNC 330
C
Sbjct: 692 HPC 694
>gi|209969800 RPE-spondin [Homo sapiens]
Length = 264
Score = 48.5 bits (114), Expect = 8e-06
Identities = 22/49 (44%), Positives = 28/49 (57%), Gaps = 1/49 (2%)
Query: 278 CEVSLWSSWGLCGGHCGRLGTKSRTRYVRVQPANNGSPCPELEEEAECV 326
C V WS W C C + T+ R R V+ +P N G+PCP LEE A C+
Sbjct: 75 CFVGEWSPWSGCADQC-KPTTRVRRRSVQQEPQNGGAPCPPLEERAGCL 122
>gi|134031945 SCO-spondin [Homo sapiens]
Length = 5147
Score = 42.7 bits (99), Expect = 4e-04
Identities = 19/49 (38%), Positives = 26/49 (53%), Gaps = 1/49 (2%)
Query: 283 WSSWGLCGGHCGRLGTKSRTRY-VRVQPANNGSPCPELEEEAECVPDNC 330
WS WG C CG LGT++R+R V P +G C ++ EC +C
Sbjct: 3817 WSPWGPCSRSCGGLGTRTRSRQCVLTMPTLSGQGCRGPRQDLECPSPDC 3865
Score = 39.7 bits (91), Expect = 0.004
Identities = 29/81 (35%), Positives = 36/81 (44%), Gaps = 7/81 (8%)
Query: 256 PVLPS----RDNEIVDSASVPETPLDCEVSLWSSWGLCGGHCGRLGTKSRTR-YVRVQPA 310
P LP RD S V P+ ++W +WG C CG G +SR R V P
Sbjct: 2530 PPLPGGSCPRDRFRSQSCFVQACPVAGAWAMWEAWGPCSVSCGG-GHQSRQRSCVDPPPK 2588
Query: 311 NNGSPCP-ELEEEAECVPDNC 330
N G+PCP +E A C C
Sbjct: 2589 NGGAPCPGASQERAPCGLQPC 2609
Score = 36.2 bits (82), Expect = 0.042
Identities = 19/48 (39%), Positives = 23/48 (47%), Gaps = 5/48 (10%)
Query: 275 PLDCEVSLWSSWGLCGGHCGRLGTKSRTRYVRVQPANNGSPCPELEEE 322
P C S WS+W C CG G +SR R + +GS PE EE
Sbjct: 4157 PTHCAWSHWSAWSPCSHSCGPRGQQSRFR-----SSTSGSWAPECREE 4199
Score = 35.4 bits (80), Expect = 0.071
Identities = 20/51 (39%), Positives = 25/51 (49%), Gaps = 2/51 (3%)
Query: 275 PLDCEVSLWSSWGLCGGHCGRLGTKSRTRYVRVQPAN-NGSPCPELEEEAE 324
PL C S WSSW C CG G ++R R PA G+PC +E +
Sbjct: 2713 PLPCGWSAWSSWAPCDRSCGS-GVRARFRSPSNPPAAWGGAPCEGDRQELQ 2762
Score = 33.9 bits (76), Expect = 0.21
Identities = 21/63 (33%), Positives = 25/63 (39%), Gaps = 10/63 (15%)
Query: 275 PLDCEVSLWSSWGLCGGHCGRLGTKSRTRYVRVQPANNGSPCPEL-------EEEAECVP 327
P+D E S WS W +C C GT +R R P N G C L + C
Sbjct: 1748 PVDGEWSTWSPWSVCSEPC--RGTMTRQRQCH-SPQNGGRTCAALPGGLHSTRQTKPCPQ 1804
Query: 328 DNC 330
D C
Sbjct: 1805 DGC 1807
Score = 32.7 bits (73), Expect = 0.46
Identities = 18/61 (29%), Positives = 26/61 (42%), Gaps = 2/61 (3%)
Query: 272 PETPLDCEVSLWSSWGLCGGHCGRLGTKSRTRYV-RVQPANNGSPCPELEEEA-ECVPDN 329
P+ +DC S WS W C G CG + R +P+ G C + +A C +
Sbjct: 1904 PDCAVDCGWSSWSPWAKCLGPCGSQSIQWSFRSSNNPRPSGRGRQCRGIHRKARRCQTEP 1963
Query: 330 C 330
C
Sbjct: 1964 C 1964
Score = 31.2 bits (69), Expect = 1.3
Identities = 19/59 (32%), Positives = 23/59 (38%), Gaps = 12/59 (20%)
Query: 275 PLDCEVSLWSSWGLCGGHCGRLGTKSRTRYVR-----------VQPANNGSPCPELEEE 322
P C+ SLW W C C G + R R Q + NG PCPE E +
Sbjct: 4613 PDSCQWSLWGPWSPCQVPCSG-GFRLRWREAEALCGGGCREPWAQESCNGGPCPECEAQ 4670
Score = 30.8 bits (68), Expect = 1.7
Identities = 19/52 (36%), Positives = 23/52 (44%), Gaps = 3/52 (5%)
Query: 281 SLWSSWGLCGGHCGRLGTKSRTRYVRVQPA-NNGSPCPELEEEAE-CVPDNC 330
S WS W C CG G R+R P+ N G+PC +A C P C
Sbjct: 4008 SRWSPWSWCDRSCGG-GQSLRSRSCSSPPSKNGGAPCAGERHQARLCNPMPC 4058
Score = 30.0 bits (66), Expect = 3.0
Identities = 15/42 (35%), Positives = 19/42 (45%), Gaps = 2/42 (4%)
Query: 276 LDCEVSLWSSWGLCGGHCGRLGTKSRTRYVRVQPANNGSPCP 317
+DC ++ WS W C CG T R +R P G CP
Sbjct: 2499 VDCVLAPWSVWSSCSRSCGLGLTFQRQELLR--PPLPGGSCP 2538
Score = 29.6 bits (65), Expect = 3.9
Identities = 15/35 (42%), Positives = 19/35 (54%), Gaps = 1/35 (2%)
Query: 281 SLWSSWGLCGGHCGRLGTKSRTRYVRVQPANNGSP 315
+LWSSW C CG G + RTR R ++ SP
Sbjct: 4257 TLWSSWSDCPVSCGG-GNQVRTRACRAAAPHHRSP 4290
Score = 28.9 bits (63), Expect = 6.6
Identities = 18/51 (35%), Positives = 23/51 (45%), Gaps = 2/51 (3%)
Query: 275 PLDCEVSLWSSWGLCGGHCGRLGTKSRTRYVRVQPAN-NGSPCPELEEEAE 324
P+ C S W+ W LC C +G + R R PA G+ C EAE
Sbjct: 2983 PVACGWSPWTLWSLCSCSC-NVGIRRRFRAGTAPPAAFGGAECQGPTMEAE 3032
Score = 28.5 bits (62), Expect = 8.7
Identities = 21/61 (34%), Positives = 27/61 (44%), Gaps = 10/61 (16%)
Query: 275 PLDCEVSLWSSWGLCGGHCGRLGTKSRTRYVRVQPANN----GSPCPELEEE-AECVPDN 329
P +C S WSSW C C L + RY PA+ G+PC L+ C+ N
Sbjct: 4363 PEECVWSSWSSWTRCS--CRVL---VQQRYRHQGPASRGARAGAPCTRLDGHFRPCLISN 4417
Query: 330 C 330
C
Sbjct: 4418 C 4418
Score = 28.5 bits (62), Expect = 8.7
Identities = 15/48 (31%), Positives = 18/48 (37%), Gaps = 1/48 (2%)
Query: 283 WSSWGLCGGHCGRLGTKSRTRYVRVQPANNGSPCPELEEEAECVPDNC 330
WS+W C CG GT R R P + E+ EC C
Sbjct: 4769 WSAWSSCSAPCGG-GTMERHRTCEGGPGVAPCQAQDTEQRQECNLQPC 4815
>gi|84490388 R-spondin1 [Homo sapiens]
Length = 263
Score = 42.0 bits (97), Expect = 8e-04
Identities = 26/77 (33%), Positives = 36/77 (46%), Gaps = 8/77 (10%)
Query: 253 PPAPVLPSRDNEIVDSASVPETPLDCEVSLWSSWGLCGGH---CG-RLGTKSRTRYVRVQ 308
P P S N ++ +S P CE+S WS WG C CG R G++ RTR V
Sbjct: 127 PACPEGSSAANGTMECSS----PAQCEMSEWSPWGPCSKKQQLCGFRRGSEERTRRVLHA 182
Query: 309 PANNGSPCPELEEEAEC 325
P + + C + +E C
Sbjct: 183 PVGDHAACSDTKETRRC 199
>gi|18490982 R-spondin 3 [Homo sapiens]
Length = 272
Score = 40.8 bits (94), Expect = 0.002
Identities = 20/52 (38%), Positives = 28/52 (53%), Gaps = 4/52 (7%)
Query: 278 CEVSLWSSWGLC---GGHCG-RLGTKSRTRYVRVQPANNGSPCPELEEEAEC 325
CEVS W+ W C G CG + GT++R R + P+ G+ CP E +C
Sbjct: 148 CEVSEWNPWSPCTKKGKTCGFKRGTETRVREIIQHPSAKGNLCPPTNETRKC 199
>gi|222446611 R-spondin family, member 2 [Homo sapiens]
Length = 243
Score = 40.4 bits (93), Expect = 0.002
Identities = 19/52 (36%), Positives = 27/52 (51%), Gaps = 4/52 (7%)
Query: 278 CEVSLWSSWGLCGGH---CG-RLGTKSRTRYVRVQPANNGSPCPELEEEAEC 325
CEV WS WG C + CG + G ++RTR + +P + CP + E C
Sbjct: 145 CEVGHWSEWGTCSRNNRTCGFKWGLETRTRQIVKKPVKDTILCPTIAESRRC 196
>gi|4557391 complement component 8, beta polypeptide preproprotein
[Homo sapiens]
Length = 591
Score = 38.1 bits (87), Expect = 0.011
Identities = 26/62 (41%), Positives = 33/62 (53%), Gaps = 8/62 (12%)
Query: 268 SASVPETPLDCEVSLWSSWGLCGGHCGRLGTKSRTRYV-RVQPAN-NGSPCPELEEEAE- 324
S V P+DCE+S WSSW C C K R RY +QP+ +G PC ++E E
Sbjct: 55 SVDVTLMPIDCELSSWSSWTTC-DPC----QKKRYRYAYLLQPSQFHGEPCNFSDKEVED 109
Query: 325 CV 326
CV
Sbjct: 110 CV 111
Score = 33.1 bits (74), Expect = 0.35
Identities = 17/44 (38%), Positives = 22/44 (50%), Gaps = 6/44 (13%)
Query: 274 TPLDCEVSLWSSWGLCGGHCGRLGTKSRTRYV-RVQPANNGSPC 316
TP+D + + WS+W C G K+R R P N GSPC
Sbjct: 542 TPIDGKWNCWSNWSSCSGR-----RKTRQRQCNNPPPQNGGSPC 580
>gi|111118994 brain-specific angiogenesis inhibitor 1 precursor
[Homo sapiens]
Length = 1584
Score = 38.1 bits (87), Expect = 0.011
Identities = 22/66 (33%), Positives = 34/66 (51%), Gaps = 4/66 (6%)
Query: 259 PSRDNEIVDSASVPETPLDCEVSLWSSWGLCGGHCGRLGTKSRTRYVRVQPANNGSPCPE 318
P R+ + ++++V P+ WS W LC CGR G + RTR R P G+PC
Sbjct: 393 PLREQRLCNNSAV--CPVHGAWDEWSPWSLCSSTCGR-GFRDRTRTCR-PPQFGGNPCEG 448
Query: 319 LEEEAE 324
E++ +
Sbjct: 449 PEKQTK 454
Score = 34.7 bits (78), Expect = 0.12
Identities = 20/50 (40%), Positives = 24/50 (48%), Gaps = 2/50 (4%)
Query: 282 LWSSWGLCGGHCGRLGTKSRTRYVRVQPANNGSPCP-ELEEEAECVPDNC 330
LWS WG C CG G ++RTR P G C LEE +C + C
Sbjct: 266 LWSLWGECTRDCGG-GLQTRTRTCLPAPGVEGGGCEGVLEEGRQCNREAC 314
Score = 32.7 bits (73), Expect = 0.46
Identities = 20/73 (27%), Positives = 30/73 (41%), Gaps = 3/73 (4%)
Query: 259 PSRDNEIVDSASVPETPLDCEVSLWSSWGLCGGHCGRLGTKSRTRYVRVQPANNGSPCP- 317
P + + + A P +D + WSSW C C + G + RTR P+ G+ C
Sbjct: 449 PEKQTKFCNIALCPGRAVDGNWNEWSSWSACSASCSQ-GRQQRTRECN-GPSYGGAECQG 506
Query: 318 ELEEEAECVPDNC 330
E +C C
Sbjct: 507 HWVETRDCFLQQC 519
Score = 31.6 bits (70), Expect = 1.0
Identities = 19/59 (32%), Positives = 29/59 (49%), Gaps = 3/59 (5%)
Query: 273 ETPLDCEVSLWSSWGLCGGHCGRLGTKSRTRYVRVQPANNGSPCPELEEE-AECVPDNC 330
+ P+D + W+SWG C CG G++ R R V P G+ C ++E +C C
Sbjct: 518 QCPVDGKWQAWASWGSCSVTCG-AGSQRRER-VCSGPFFGGAACQGPQDEYRQCGTQRC 574
>gi|145699139 cartilage intermediate layer protein 2 [Homo sapiens]
Length = 1156
Score = 37.0 bits (84), Expect = 0.024
Identities = 21/57 (36%), Positives = 26/57 (45%), Gaps = 5/57 (8%)
Query: 275 PLDCEVSLWSSWGLCGGHCGRLGTKSRTRYVRVQPANNGSPCPELEEEAE-CVPDNC 330
PL+ W WG C G CG G + R R+ P+ G CP EA+ CV C
Sbjct: 144 PLEASWGAWGPWGPCSGSCGP-GRRLRRRHC---PSPAGDACPGRPLEAQKCVRPRC 196
>gi|192449445 cartilage intermediate layer protein [Homo sapiens]
Length = 1184
Score = 36.2 bits (82), Expect = 0.042
Identities = 19/51 (37%), Positives = 26/51 (50%), Gaps = 4/51 (7%)
Query: 281 SLWSSWGLCGGHCGRLGTKSRTRYVRVQPANNGSPCPELEEEAE-CVPDNC 330
S WS W C CG+ G ++RT R+ A S C E EE + C+ +C
Sbjct: 153 SPWSPWSKCSAACGQTGVQTRT---RICLAEMVSLCSEASEEGQHCMGQDC 200
>gi|115387099 brain-specific angiogenesis inhibitor 2 [Homo sapiens]
Length = 1585
Score = 35.4 bits (80), Expect = 0.071
Identities = 19/40 (47%), Positives = 23/40 (57%), Gaps = 4/40 (10%)
Query: 283 WSSWGLCGGHCGRLGTKSRTRYVRVQPANNGSPC--PELE 320
W SW LC CGR G++SR R V P + G C PEL+
Sbjct: 370 WGSWSLCSRSCGR-GSRSRMR-TCVPPQHGGKACEGPELQ 407
>gi|118572606 hemicentin 1 [Homo sapiens]
Length = 5635
Score = 35.0 bits (79), Expect = 0.093
Identities = 20/52 (38%), Positives = 25/52 (48%), Gaps = 3/52 (5%)
Query: 281 SLWSSWGLCGGHCGRLGTKSRTRYV-RVQPANNGSPCPELEEEAE-CVPDNC 330
S W WG C CG+ GT++R R PA GS C E + + C NC
Sbjct: 4647 SAWQPWGTCSESCGK-GTQTRARLCNNPPPAFGGSYCDGAETQMQVCNERNC 4697
Score = 33.5 bits (75), Expect = 0.27
Identities = 17/44 (38%), Positives = 19/44 (43%), Gaps = 2/44 (4%)
Query: 275 PLDCEVSLWSSWGLCGGHCGRLGTKSRTRYV-RVQPANNGSPCP 317
P+D W SW C CG G K+R R P G PCP
Sbjct: 4812 PVDGSWGSWHSWSQCSASCGG-GEKTRKRLCDHPVPVKGGRPCP 4854
Score = 33.1 bits (74), Expect = 0.35
Identities = 16/37 (43%), Positives = 21/37 (56%), Gaps = 2/37 (5%)
Query: 281 SLWSSWGLCGGHCGRLGTKSRTRYV-RVQPANNGSPC 316
S WS+W C CG+ G + R+R + PAN G PC
Sbjct: 4533 SQWSAWRACSVTCGK-GIQKRSRLCNQPLPANGGKPC 4568
Score = 30.0 bits (66), Expect = 3.0
Identities = 17/43 (39%), Positives = 21/43 (48%), Gaps = 2/43 (4%)
Query: 275 PLDCEVSLWSSWGLCGGHCGRLGTKSRTRYVRVQPANNGS-PC 316
P+D S WS W C CGR G ++RTR +G PC
Sbjct: 4584 PVDGSWSEWSLWEECTRSCGR-GNQTRTRTCNNPSVQHGGRPC 4625
>gi|209977117 unc-5 homolog D [Homo sapiens]
Length = 953
Score = 34.7 bits (78), Expect = 0.12
Identities = 18/58 (31%), Positives = 25/58 (43%), Gaps = 4/58 (6%)
Query: 275 PLDCEVSLWSSWGLCGGHCGRLGTKSRTRYVRVQPANNGSPCPELEEEAE-CVPDNCV 331
P+D +WS W +C C L + T P N G C L +E+E C C+
Sbjct: 306 PVDGSWEVWSEWSVCSPECEHLRIRECT---APPPRNGGKFCEGLSQESENCTDGLCI 360
Score = 28.9 bits (63), Expect = 6.6
Identities = 12/36 (33%), Positives = 14/36 (38%)
Query: 281 SLWSSWGLCGGHCGRLGTKSRTRYVRVQPANNGSPC 316
S W+ W C CGR K P N G+ C
Sbjct: 256 SSWTEWSACNVRCGRGWQKRSRTCTNPAPLNGGAFC 291
>gi|87116683 proline/serine-rich coiled-coil 2 [Homo sapiens]
Length = 1989
Score = 33.9 bits (76), Expect = 0.21
Identities = 28/104 (26%), Positives = 45/104 (43%), Gaps = 23/104 (22%)
Query: 181 ALDLYPYDAGTDSGFTFSSPNFATIPQDTVTEITSSSPSHPANSFYY------------- 227
+LD P D+G G + N+ + DT +E +S +PS F+
Sbjct: 510 SLDKQPTDSG---GGIYQYDNYEEVAMDTDSETSSPAPSPVQPPFFSECSLGYFSPAPSL 566
Query: 228 -----PRLKALPPIARVTLVRLRQS--PRAFIPPAPVLPSRDNE 264
P++ +LPP+++ + L S P +PP P LP D E
Sbjct: 567 SLPPPPQVSSLPPLSQPYVEGLCVSLEPLPPLPPLPPLPPEDPE 610
>gi|4505737 complement factor properdin precursor [Homo sapiens]
Length = 469
Score = 33.1 bits (74), Expect = 0.35
Identities = 15/34 (44%), Positives = 19/34 (55%)
Query: 270 SVPETPLDCEVSLWSSWGLCGGHCGRLGTKSRTR 303
S+ PL S WS+WGLC CG T++R R
Sbjct: 372 SIQHCPLKGSWSEWSTWGLCMPPCGPNPTRARQR 405
>gi|4502359 brain-specific angiogenesis inhibitor 3 [Homo sapiens]
Length = 1522
Score = 33.1 bits (74), Expect = 0.35
Identities = 19/58 (32%), Positives = 29/58 (50%), Gaps = 4/58 (6%)
Query: 259 PSRDNEIVDSASVPETPLDCEVSLWSSWGLCGGHCGRLGTKSRTRYVRVQPANNGSPC 316
P R++ + ++ ++ P+ WS W LC CGR G ++RTR P G PC
Sbjct: 329 PLRESRVCNNTAL--CPVHGVWEEWSPWSLCSFTCGR-GQRTRTRSC-TPPQYGGRPC 382
Score = 32.0 bits (71), Expect = 0.78
Identities = 20/57 (35%), Positives = 25/57 (43%), Gaps = 3/57 (5%)
Query: 275 PLDCEVSLWSSWGLCGGHCGRLGTKSRTRYVRVQPANNGSPC-PELEEEAECVPDNC 330
P+D + WSSW C C GT+ R+R A+ GS C E EC C
Sbjct: 398 PVDGQWQEWSSWSQCSVTCSN-GTQQRSRQC-TAAAHGGSECRGPWAESRECYNPEC 452
>gi|223671861 complement factor properdin precursor [Homo sapiens]
Length = 469
Score = 33.1 bits (74), Expect = 0.35
Identities = 15/34 (44%), Positives = 19/34 (55%)
Query: 270 SVPETPLDCEVSLWSSWGLCGGHCGRLGTKSRTR 303
S+ PL S WS+WGLC CG T++R R
Sbjct: 372 SIQHCPLKGSWSEWSTWGLCMPPCGPNPTRARQR 405
>gi|4502511 complement component 9 precursor [Homo sapiens]
Length = 559
Score = 32.7 bits (73), Expect = 0.46
Identities = 22/69 (31%), Positives = 34/69 (49%), Gaps = 5/69 (7%)
Query: 260 SRDNEIVDSASVPETPLDCEVSLWSSWGLCGGHCGRLGTKSRTRYVRVQPANNGSPCPE- 318
S D E+ +S+ + +DC +S WS W C C L R+R + V NG C +
Sbjct: 26 SYDPELTESSG-SASHIDCRMSPWSEWSQC-DPC--LRQMFRSRSIEVFGQFNGKRCTDA 81
Query: 319 LEEEAECVP 327
+ + +CVP
Sbjct: 82 VGDRRQCVP 90
>gi|158187511 T-box 22 isoform 2 [Homo sapiens]
Length = 400
Score = 32.7 bits (73), Expect = 0.46
Identities = 39/144 (27%), Positives = 58/144 (40%), Gaps = 9/144 (6%)
Query: 176 WREQAALDLYPYDAGTDSGFTFSSP----NFATIPQDTVTEITSSSPSH--PANSFYYPR 229
WR LD + A T SG + SSP A P +++ SP P +S P
Sbjct: 180 WRPSFTLDFKTFGADTQSGSSGSSPVTSSGGAPSPLNSLLSPLCFSPMFHLPTSSLGMPC 239
Query: 230 LKALPPIARVTLVRLRQSPRAFIPPAP-VLPSRDNEIVDSASVPETPLDCEVSLWSSWGL 288
+A P + L + P F P VLP+ + ++S PL EV + SS G+
Sbjct: 240 PEAYLPNVNLPLC-YKICPTNFWQQQPLVLPAPERLASSNSSQSLAPLMMEVPMLSSLGV 298
Query: 289 CGGHCGRLGTKSRTRYVRVQPANN 312
G S +Y++ + N
Sbjct: 299 TNSKSGS-SEDSSDQYLQAPNSTN 321
>gi|158187509 T-box 22 isoform 1 [Homo sapiens]
Length = 520
Score = 32.7 bits (73), Expect = 0.46
Identities = 39/144 (27%), Positives = 58/144 (40%), Gaps = 9/144 (6%)
Query: 176 WREQAALDLYPYDAGTDSGFTFSSP----NFATIPQDTVTEITSSSPSH--PANSFYYPR 229
WR LD + A T SG + SSP A P +++ SP P +S P
Sbjct: 300 WRPSFTLDFKTFGADTQSGSSGSSPVTSSGGAPSPLNSLLSPLCFSPMFHLPTSSLGMPC 359
Query: 230 LKALPPIARVTLVRLRQSPRAFIPPAP-VLPSRDNEIVDSASVPETPLDCEVSLWSSWGL 288
+A P + L + P F P VLP+ + ++S PL EV + SS G+
Sbjct: 360 PEAYLPNVNLPLC-YKICPTNFWQQQPLVLPAPERLASSNSSQSLAPLMMEVPMLSSLGV 418
Query: 289 CGGHCGRLGTKSRTRYVRVQPANN 312
G S +Y++ + N
Sbjct: 419 TNSKSGS-SEDSSDQYLQAPNSTN 441
>gi|18375603 T-box 22 isoform 1 [Homo sapiens]
Length = 520
Score = 32.7 bits (73), Expect = 0.46
Identities = 39/144 (27%), Positives = 58/144 (40%), Gaps = 9/144 (6%)
Query: 176 WREQAALDLYPYDAGTDSGFTFSSP----NFATIPQDTVTEITSSSPSH--PANSFYYPR 229
WR LD + A T SG + SSP A P +++ SP P +S P
Sbjct: 300 WRPSFTLDFKTFGADTQSGSSGSSPVTSSGGAPSPLNSLLSPLCFSPMFHLPTSSLGMPC 359
Query: 230 LKALPPIARVTLVRLRQSPRAFIPPAP-VLPSRDNEIVDSASVPETPLDCEVSLWSSWGL 288
+A P + L + P F P VLP+ + ++S PL EV + SS G+
Sbjct: 360 PEAYLPNVNLPLC-YKICPTNFWQQQPLVLPAPERLASSNSSQSLAPLMMEVPMLSSLGV 418
Query: 289 CGGHCGRLGTKSRTRYVRVQPANN 312
G S +Y++ + N
Sbjct: 419 TNSKSGS-SEDSSDQYLQAPNSTN 441
>gi|122937388 MAX gene associated [Homo sapiens]
Length = 3114
Score = 32.7 bits (73), Expect = 0.46
Identities = 26/114 (22%), Positives = 47/114 (41%), Gaps = 18/114 (15%)
Query: 213 ITSSSPSHPANSFYYPRLKALPPIARVTLVRLRQSPRAFIP-PAPVLPSRDNEIVDSASV 271
I + S P P+ + L P + L+ +SPR++ P P PV+ D +
Sbjct: 1174 IPTPSVIEPMKPLLLPQPEVLSPTVKGKLLTGIKSPRSYTPKPNPVIREEDKD------- 1226
Query: 272 PETPLDCEVSLWSSWGLCGGHCGRLGTKSRTRYVRVQPANNGSPCPELEEEAEC 325
V L+ + C R+ R + + QP+++ SP P +++ C
Sbjct: 1227 -------PVYLYFESMMT---CARVRVYERKKEDQRQPSSSSSPSPSFQQQTSC 1270
>gi|16933525 unc5C [Homo sapiens]
Length = 931
Score = 32.0 bits (71), Expect = 0.78
Identities = 15/37 (40%), Positives = 19/37 (51%), Gaps = 2/37 (5%)
Query: 281 SLWSSWGLCGGHCGRLGTKSRTR-YVRVQPANNGSPC 316
S W+ W +C CGR G + RTR P N G+ C
Sbjct: 264 STWTEWSVCNSRCGR-GYQKRTRTCTNPAPLNGGAFC 299
>gi|110611170 ADAM metallopeptidase with thrombospondin type 1
motif, 17 preproprotein [Homo sapiens]
Length = 1095
Score = 32.0 bits (71), Expect = 0.78
Identities = 19/66 (28%), Positives = 27/66 (40%), Gaps = 2/66 (3%)
Query: 261 RDNEIVDSASVPETPLDCEVSLWSSWGLCGGHCGRLGTKSRTRYVRVQPANNGSPCPELE 320
R E V +PE +D + S W +W +C CG + + P G+ CP
Sbjct: 528 RAGECVSKTPIPEH-VDGDWSPWGAWSMCSRTCGTGARFRQRKCDNPPPGPGGTHCPGAS 586
Query: 321 -EEAEC 325
E A C
Sbjct: 587 VEHAVC 592
>gi|40317626 thrombospondin 1 precursor [Homo sapiens]
Length = 1170
Score = 31.6 bits (70), Expect = 1.0
Identities = 20/52 (38%), Positives = 21/52 (40%), Gaps = 3/52 (5%)
Query: 281 SLWSSWGLCGGHCGRLGTKSRTRYVR-VQPANNGSPCP-ELEEEAECVPDNC 330
S WS W C CG G +R R P NG PC E E C D C
Sbjct: 439 SHWSPWSSCSVTCGD-GVITRIRLCNSPSPQMNGKPCEGEARETKACKKDAC 489
>gi|14790190 spen homolog, transcriptional regulator [Homo sapiens]
Length = 3664
Score = 31.6 bits (70), Expect = 1.0
Identities = 33/131 (25%), Positives = 54/131 (41%), Gaps = 16/131 (12%)
Query: 129 VPSGTGQTSAELEVQRRHSLVSFVVRIVPSPDWFVGVDSLDLCDGDRWREQAALDLYPYD 188
+PS T +S E+ V+ R + V +P P VD R+R + ++ P
Sbjct: 2405 IPS-TENSSQEISVEERTPTKASVPPDLPPPPQPAPVDEEPQA---RFRVHSIIESDPV- 2459
Query: 189 AGTDSGFTFSSPNFATIPQDTVTEITSSSPSHPANSFYYPRLKALPPIARVTLVRLRQSP 248
+ P+ +IP T+ +T++ S P S P PP + ++ P
Sbjct: 2460 ---------TPPSDPSIPIPTLPSVTAAKLSPPVASGGIPHQS--PPTKVTEWITRQEEP 2508
Query: 249 RAFIPPAPVLP 259
RA P+P LP
Sbjct: 2509 RAQSTPSPALP 2519
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.132 0.414
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,326,583
Number of Sequences: 37866
Number of extensions: 768851
Number of successful extensions: 2393
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 25
Number of HSP's successfully gapped in prelim test: 54
Number of HSP's that attempted gapping in prelim test: 2261
Number of HSP's gapped (non-prelim): 165
length of query: 331
length of database: 18,247,518
effective HSP length: 103
effective length of query: 228
effective length of database: 14,347,320
effective search space: 3271188960
effective search space used: 3271188960
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.