Guide to the Human Genome
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Search of human proteins with 6912662

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|6912662 sirtuin 4 [Homo sapiens]
         (314 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|6912662 sirtuin 4 [Homo sapiens]                                   652   0.0  
gi|6912664 sirtuin 5 isoform 1 [Homo sapiens]                         109   3e-24
gi|13787215 sirtuin 5 isoform 2 [Homo sapiens]                        104   9e-23
gi|7706710 sirtuin 6 [Homo sapiens]                                    87   3e-17
gi|7706712 sirtuin 7 [Homo sapiens]                                    86   3e-17
gi|6912660 sirtuin 3 isoform a [Homo sapiens]                          85   7e-17
gi|7657575 sirtuin 1 isoform a [Homo sapiens]                          80   2e-15
gi|63054862 sirtuin 3 isoform b [Homo sapiens]                         80   2e-15
gi|13775600 sirtuin 2 isoform 1 [Homo sapiens]                         73   3e-13
gi|13775602 sirtuin 2 isoform 2 [Homo sapiens]                         73   3e-13
gi|215982798 sirtuin 1 isoform b [Homo sapiens]                        57   2e-08
gi|190358526 hypothetical protein LOC54785 [Homo sapiens]              29   4.7  
gi|196049380 3-hydroxy-3-methylglutaryl-Coenzyme A reductase iso...    29   6.2  
gi|4557643 3-hydroxy-3-methylglutaryl-Coenzyme A reductase isofo...    29   6.2  
gi|163965366 nascent polypeptide-associated complex alpha subuni...    29   6.2  
gi|110349719 titin isoform N2-A [Homo sapiens]                         28   8.1  
gi|164663805 methyltransferase like 7B [Homo sapiens]                  28   8.1  

>gi|6912662 sirtuin 4 [Homo sapiens]
          Length = 314

 Score =  652 bits (1681), Expect = 0.0
 Identities = 314/314 (100%), Positives = 314/314 (100%)

Query: 1   MKMSFALTFRSAKGRWIANPSQPCSKASIGLFVPASPPLDPEKVKELQRFITLSKRLLVM 60
           MKMSFALTFRSAKGRWIANPSQPCSKASIGLFVPASPPLDPEKVKELQRFITLSKRLLVM
Sbjct: 1   MKMSFALTFRSAKGRWIANPSQPCSKASIGLFVPASPPLDPEKVKELQRFITLSKRLLVM 60

Query: 61  TGAGISTESGIPDYRSEKVGLYARTDRRPIQHGDFVRSAPIRQRYWARNFVGWPQFSSHQ 120
           TGAGISTESGIPDYRSEKVGLYARTDRRPIQHGDFVRSAPIRQRYWARNFVGWPQFSSHQ
Sbjct: 61  TGAGISTESGIPDYRSEKVGLYARTDRRPIQHGDFVRSAPIRQRYWARNFVGWPQFSSHQ 120

Query: 121 PNPAHWALSTWEKLGKLYWLVTQNVDALHTKAGSRRLTELHGCMDRVLCLDCGEQTPRGV 180
           PNPAHWALSTWEKLGKLYWLVTQNVDALHTKAGSRRLTELHGCMDRVLCLDCGEQTPRGV
Sbjct: 121 PNPAHWALSTWEKLGKLYWLVTQNVDALHTKAGSRRLTELHGCMDRVLCLDCGEQTPRGV 180

Query: 181 LQERFQVLNPTWSAEAHGLAPDGDVFLSEEQVRSFQVPTCVQCGGHLKPDVVFFGDTVNP 240
           LQERFQVLNPTWSAEAHGLAPDGDVFLSEEQVRSFQVPTCVQCGGHLKPDVVFFGDTVNP
Sbjct: 181 LQERFQVLNPTWSAEAHGLAPDGDVFLSEEQVRSFQVPTCVQCGGHLKPDVVFFGDTVNP 240

Query: 241 DKVDFVHKRVKEADSLLVVGSSLQVYSGYRFILTAWEKKLPIAILNIGPTRSDDLACLKL 300
           DKVDFVHKRVKEADSLLVVGSSLQVYSGYRFILTAWEKKLPIAILNIGPTRSDDLACLKL
Sbjct: 241 DKVDFVHKRVKEADSLLVVGSSLQVYSGYRFILTAWEKKLPIAILNIGPTRSDDLACLKL 300

Query: 301 NSRCGELLPLIDPC 314
           NSRCGELLPLIDPC
Sbjct: 301 NSRCGELLPLIDPC 314


>gi|6912664 sirtuin 5 isoform 1 [Homo sapiens]
          Length = 310

 Score =  109 bits (273), Expect = 3e-24
 Identities = 83/304 (27%), Positives = 140/304 (46%), Gaps = 27/304 (8%)

Query: 20  PSQPCSKASIGLFVPASP--------PLDPEKVKELQRFITLSKRLLVMTGAGISTESGI 71
           PS+  S+   GL  PAS               + + ++F   +K +++++GAG+S ESG+
Sbjct: 8   PSRLISQLYCGLKPPASTRNQICLKMARPSSSMADFRKFFAKAKHIVIISGAGVSAESGV 67

Query: 72  PDYRSEKVGLYARTDRRPIQHGDFVRSAPIRQRYWARNFVGWPQFSSHQPNPAHWALSTW 131
           P +R    G + +   + +         P   R W           S +PN  H A++  
Sbjct: 68  PTFRGAG-GYWRKWQAQDLATPLAFAHNP--SRVWEFYHYRREVMGSKEPNAGHRAIAEC 124

Query: 132 E----KLGKLYWLVTQNVDALHTKAGSRRLTELHGCMDRVLCLDCGEQTPRGVLQERFQV 187
           E    K G+   ++TQN+D LH KAG++ L E+HG + +  C  CG      V+ E ++ 
Sbjct: 125 ETRLGKQGRRVVVITQNIDELHRKAGTKNLLEIHGSLFKTRCTSCG------VVAENYK- 177

Query: 188 LNPTWSAEAHGLAPDGDVFLSEEQVRSFQVPTCVQ--CGGHLKPDVVFFGDTVNPDKVDF 245
            +P   A +   AP+      +  +   ++P C +  CGG L+P VV+FG+ ++P  ++ 
Sbjct: 178 -SPICPALSGKGAPEPGT--QDASIPVEKLPRCEEAGCGGLLRPHVVWFGENLDPAILEE 234

Query: 246 VHKRVKEADSLLVVGSSLQVYSGYRFILTAWEKKLPIAILNIGPTRSDDLACLKLNSRCG 305
           V + +   D  LVVG+S  VY    F      + +P+A  N   T + +         CG
Sbjct: 235 VDRELAHCDLCLVVGTSSVVYPAAMFAPQVAARGVPVAEFNTETTPATNRFRFHFQGPCG 294

Query: 306 ELLP 309
             LP
Sbjct: 295 TTLP 298


>gi|13787215 sirtuin 5 isoform 2 [Homo sapiens]
          Length = 299

 Score =  104 bits (260), Expect = 9e-23
 Identities = 79/285 (27%), Positives = 134/285 (47%), Gaps = 27/285 (9%)

Query: 20  PSQPCSKASIGLFVPASP--------PLDPEKVKELQRFITLSKRLLVMTGAGISTESGI 71
           PS+  S+   GL  PAS               + + ++F   +K +++++GAG+S ESG+
Sbjct: 8   PSRLISQLYCGLKPPASTRNQICLKMARPSSSMADFRKFFAKAKHIVIISGAGVSAESGV 67

Query: 72  PDYRSEKVGLYARTDRRPIQHGDFVRSAPIRQRYWARNFVGWPQFSSHQPNPAHWALSTW 131
           P +R    G + +   + +         P   R W           S +PN  H A++  
Sbjct: 68  PTFRGAG-GYWRKWQAQDLATPLAFAHNP--SRVWEFYHYRREVMGSKEPNAGHRAIAEC 124

Query: 132 E----KLGKLYWLVTQNVDALHTKAGSRRLTELHGCMDRVLCLDCGEQTPRGVLQERFQV 187
           E    K G+   ++TQN+D LH KAG++ L E+HG + +  C  C      GV+ E ++ 
Sbjct: 125 ETRLGKQGRRVVVITQNIDELHRKAGTKNLLEIHGSLFKTRCTSC------GVVAENYK- 177

Query: 188 LNPTWSAEAHGLAPDGDVFLSEEQVRSFQVPTCVQ--CGGHLKPDVVFFGDTVNPDKVDF 245
            +P   A +   AP+      +  +   ++P C +  CGG L+P VV+FG+ ++P  ++ 
Sbjct: 178 -SPICPALSGKGAPEPGT--QDASIPVEKLPRCEEAGCGGLLRPHVVWFGENLDPAILEE 234

Query: 246 VHKRVKEADSLLVVGSSLQVYSGYRFILTAWEKKLPIAILNIGPT 290
           V + +   D  LVVG+S  VY    F      + +P+A  N   T
Sbjct: 235 VDRELAHCDLCLVVGTSSVVYPAAMFAPQVAARGVPVAEFNTETT 279


>gi|7706710 sirtuin 6 [Homo sapiens]
          Length = 355

 Score = 86.7 bits (213), Expect = 3e-17
 Identities = 84/296 (28%), Positives = 128/296 (43%), Gaps = 41/296 (13%)

Query: 16  WIANPSQPCSKASIGLFVPASPPLDPE-KVKELQRFITLSKRLLVMTGAGISTESGIPDY 74
           + A  S    K   GL     PP + E KV EL R +  S  ++  TGAGIST SGIPD+
Sbjct: 5   YAAGLSPYADKGKCGLPEIFDPPEELERKVWELARLVWQSSSVVFHTGAGISTASGIPDF 64

Query: 75  RSEKVGLYARTDRRPIQHGDFVRSAPIRQRYWARNFVGWPQFSSHQPNPAHWALSTWEKL 134
           R                HG +     + +R  A  F     F S +P   H AL   E++
Sbjct: 65  RGP--------------HGVWT----MEERGLAPKFD--TTFESARPTQTHMALVQLERV 104

Query: 135 GKLYWLVTQNVDALHTKAGSRR--LTELHGCMDRVLCLDCGEQTPRGVLQERFQVLNPTW 192
           G L +LV+QNVD LH ++G  R  L ELHG M    C  C  Q  R  +           
Sbjct: 105 GLLRFLVSQNVDGLHVRSGFPRDKLAELHGNMFVEECAKCKTQYVRDTV----------- 153

Query: 193 SAEAHGLAPDGDVFLSEEQVRSFQVPTCVQCGGHLKPDVVFFGDTVNPDKVDFVHKRVKE 252
                GL   G +  +  + R  +      C G L+  ++ + D++    +    +  + 
Sbjct: 154 -VGTMGLKATGRL-CTVAKARGLRA-----CRGELRDTILDWEDSLPDRDLALADEASRN 206

Query: 253 ADSLLVVGSSLQVYSGYRFILTAWEKKLPIAILNIGPTRSDDLACLKLNSRCGELL 308
           AD  + +G+SLQ+       L    +   + I+N+ PT+ D  A L+++    E++
Sbjct: 207 ADLSITLGTSLQIRPSGNLPLATKRRGGRLVIVNLQPTKHDRHADLRIHGYVDEVM 262


>gi|7706712 sirtuin 7 [Homo sapiens]
          Length = 400

 Score = 86.3 bits (212), Expect = 3e-17
 Identities = 81/284 (28%), Positives = 129/284 (45%), Gaps = 54/284 (19%)

Query: 40  DPE----KVKELQRFITLSKRLLVMTGAGISTESGIPDYRSEKVGLYARTDRRPIQHGDF 95
           DPE    KV+EL   +  +K L+V TGAGIST + IPDYR    G++       +Q G  
Sbjct: 81  DPEELRGKVRELASAVRNAKYLVVYTGAGISTAASIPDYRGPN-GVWTL-----LQKGRS 134

Query: 96  VRSAPIRQRYWARNFVGWPQFSSHQPNPAHWALSTWEKLGKLYWLVTQNVDALHTKAGSR 155
           V +A +               S  +P   H +++   +   +  +V+QN D LH ++G  
Sbjct: 135 VSAADL---------------SEAEPTLTHMSITRLHEQKLVQHVVSQNCDGLHLRSGLP 179

Query: 156 R--LTELHGCMDRVLCLDCGEQTPRGVLQERFQVLNPTWSAEAHGLAPDGDVFLSEEQVR 213
           R  ++ELHG M   +C  C         +E  +V + T     H               R
Sbjct: 180 RTAISELHGNMYIEVCTSCVPN------REYVRVFDVTERTALH---------------R 218

Query: 214 SFQVPTCVQCGGHLKPDVVFFGD---TVNPDKVDFVHKRVKEADSLLVVGSSLQVYSGY- 269
                TC +CG  L+  +V FG+      P   +   +    AD++L +GSSL+V   Y 
Sbjct: 219 HQTGRTCHKCGTQLRDTIVHFGERGTLGQPLNWEAATEAASRADTILCLGSSLKVLKKYP 278

Query: 270 -RFILTAWEKKLP-IAILNIGPTRSDDLACLKLNSRCGELLPLI 311
             + +T    + P + I+N+  T  DD A LKL+ +C +++ L+
Sbjct: 279 RLWCMTKPPSRRPKLYIVNLQWTPKDDWAALKLHGKCDDVMRLL 322


>gi|6912660 sirtuin 3 isoform a [Homo sapiens]
          Length = 399

 Score = 85.1 bits (209), Expect = 7e-17
 Identities = 76/255 (29%), Positives = 114/255 (44%), Gaps = 40/255 (15%)

Query: 55  KRLLVMTGAGISTESGIPDYRSEKVGLYARTDRRPIQHGDFVRSAPIRQRYWARNFVGWP 114
           +R++VM GAGIST SGIPD+RS   GLY+   +  + + + +   P         F    
Sbjct: 138 QRVVVMVGAGISTPSGIPDFRSPGSGLYSNLQQYDLPYPEAIFELPFFFHNPKPFFTLAK 197

Query: 115 QF--SSHQPNPAHWALSTWEKLGKLYWLVTQNVDALHTKAG--SRRLTELHGCMDRVLCL 170
           +    +++PN  H+ L      G L  L TQN+D L   +G  + +L E HG      C 
Sbjct: 198 ELYPGNYKPNVTHYFLRLLHDKGLLLRLYTQNIDGLERVSGIPASKLVEAHGTFASATCT 257

Query: 171 DCGEQTPRGVLQERFQVLNPTWSAEAHGLAPDGDVFLSEEQVRSFQVPTCVQCGGHLKPD 230
            C         Q  F               P  D+      V + +VP C  C G +KPD
Sbjct: 258 VC---------QRPF---------------PGEDI---RADVMADRVPRCPVCTGVVKPD 290

Query: 231 VVFFGDTVNPDKVDFVHKRVKEADSLLVVGSSLQVYSGYRFILTAWEKKLPIAILN---I 287
           +VFFG+ + P +          AD LL++G+SL+V   +  +  A    +P  ++N   +
Sbjct: 291 IVFFGEPL-PQRFLLHVVDFPMADLLLILGTSLEV-EPFASLTEAVRSSVPRLLINRDLV 348

Query: 288 GP----TRSDDLACL 298
           GP     RS D+A L
Sbjct: 349 GPLAWHPRSRDVAQL 363


>gi|7657575 sirtuin 1 isoform a [Homo sapiens]
          Length = 747

 Score = 80.5 bits (197), Expect = 2e-15
 Identities = 73/240 (30%), Positives = 115/240 (47%), Gaps = 47/240 (19%)

Query: 40  DPEKVKELQRFITLSKRLLVMTGAGISTESGIPDYRSEKVGLYART--------DRRPIQ 91
           D   +++  + +   K+++V+TGAG+S   GIPD+RS   G+YAR         D + + 
Sbjct: 239 DINTIEDAVKLLQECKKIIVLTGAGVSVSCGIPDFRSRD-GIYARLAVDFPDLPDPQAMF 297

Query: 92  HGDFVRSAPIRQRYWARNFVGWPQFSSHQPNPAHWALSTWEKLGKLYWLVTQNVDALHTK 151
             ++ R  P     +A+    +P     QP+  H  ++  +K GKL    TQN+D L   
Sbjct: 298 DIEYFRKDPRPFFKFAKEI--YP--GQFQPSLCHKFIALSDKEGKLLRNYTQNIDTLEQV 353

Query: 152 AGSRRLTELHGCMDRVLCLDCGEQTPRGVLQERFQVLNPTWSAEAHGLAPDGDVFLSEEQ 211
           AG +R+ + HG      CL C           +++V       E    A  GD+F    Q
Sbjct: 354 AGIQRIIQCHGSFATASCLIC-----------KYKV-----DCE----AVRGDIF---NQ 390

Query: 212 VRSFQVPTCVQCGGH-----LKPDVVFFGDTVNPDKVDFVHKRVK-EADSLLVVGSSLQV 265
           V    VP C +C        +KP++VFFG+ + P++     K  K E D L+V+GSSL+V
Sbjct: 391 V----VPRCPRCPADEPLAIMKPEIVFFGENL-PEQFHRAMKYDKDEVDLLIVIGSSLKV 445


>gi|63054862 sirtuin 3 isoform b [Homo sapiens]
          Length = 257

 Score = 80.5 bits (197), Expect = 2e-15
 Identities = 74/250 (29%), Positives = 109/250 (43%), Gaps = 40/250 (16%)

Query: 60  MTGAGISTESGIPDYRSEKVGLYARTDRRPIQHGDFVRSAPIRQRYWARNFVGWPQF--S 117
           M GAGIST SGIPD+RS   GLY+   +  + + + +   P         F    +    
Sbjct: 1   MVGAGISTPSGIPDFRSPGSGLYSNLQQYDLPYPEAIFELPFFFHNPKPFFTLAKELYPG 60

Query: 118 SHQPNPAHWALSTWEKLGKLYWLVTQNVDALHTKAG--SRRLTELHGCMDRVLCLDCGEQ 175
           +++PN  H+ L      G L  L TQN+D L   +G  + +L E HG      C  C   
Sbjct: 61  NYKPNVTHYFLRLLHDKGLLLRLYTQNIDGLERVSGIPASKLVEAHGTFASATCTVC--- 117

Query: 176 TPRGVLQERFQVLNPTWSAEAHGLAPDGDVFLSEEQVRSFQVPTCVQCGGHLKPDVVFFG 235
                 Q  F               P  D+      V + +VP C  C G +KPD+VFFG
Sbjct: 118 ------QRPF---------------PGEDI---RADVMADRVPRCPVCTGVVKPDIVFFG 153

Query: 236 DTVNPDKVDFVHKRVKEADSLLVVGSSLQVYSGYRFILTAWEKKLPIAILN---IGP--- 289
           + + P +          AD LL++G+SL+V   +  +  A    +P  ++N   +GP   
Sbjct: 154 EPL-PQRFLLHVVDFPMADLLLILGTSLEV-EPFASLTEAVRSSVPRLLINRDLVGPLAW 211

Query: 290 -TRSDDLACL 298
             RS D+A L
Sbjct: 212 HPRSRDVAQL 221


>gi|13775600 sirtuin 2 isoform 1 [Homo sapiens]
          Length = 389

 Score = 73.2 bits (178), Expect = 3e-13
 Identities = 57/217 (26%), Positives = 94/217 (43%), Gaps = 33/217 (15%)

Query: 55  KRLLVMTGAGISTESGIPDYRSEKVGLYARTDRRPIQHGDFVRSAPIRQRYWARNFVGWP 114
           +R++ + GAGIST +GIPD+RS   GLY   ++  + + + +      +++    F    
Sbjct: 77  RRVICLVGAGISTSAGIPDFRSPSTGLYDNLEKYHLPYPEAIFEISYFKKHPEPFFALAK 136

Query: 115 QF--SSHQPNPAHWALSTWEKLGKLYWLVTQNVDALHTKAGSRR--LTELHGCMDRVLCL 170
           +      +P   H+ +   +  G L    TQN+D L   AG  +  L E HG      C+
Sbjct: 137 ELYPGQFKPTICHYFMRLLKDKGLLLRCYTQNIDTLERIAGLEQEDLVEAHGTFYTSHCV 196

Query: 171 --DCGEQTPRGVLQERFQVLNPTWSAEAHGLAPDGDVFLSEEQVRSFQVPTCVQCGGHLK 228
              C  + P             +W                +E++ S   P C  C   +K
Sbjct: 197 SASCRHEYPL------------SW---------------MKEKIFSEVTPKCEDCQSLVK 229

Query: 229 PDVVFFGDTVNPDKVDFVHKRVKEADSLLVVGSSLQV 265
           PD+VFFG+++       +     + D LLV+G+SLQV
Sbjct: 230 PDIVFFGESLPARFFSCMQSDFLKVDLLLVMGTSLQV 266


>gi|13775602 sirtuin 2 isoform 2 [Homo sapiens]
          Length = 352

 Score = 73.2 bits (178), Expect = 3e-13
 Identities = 57/217 (26%), Positives = 94/217 (43%), Gaps = 33/217 (15%)

Query: 55  KRLLVMTGAGISTESGIPDYRSEKVGLYARTDRRPIQHGDFVRSAPIRQRYWARNFVGWP 114
           +R++ + GAGIST +GIPD+RS   GLY   ++  + + + +      +++    F    
Sbjct: 40  RRVICLVGAGISTSAGIPDFRSPSTGLYDNLEKYHLPYPEAIFEISYFKKHPEPFFALAK 99

Query: 115 QF--SSHQPNPAHWALSTWEKLGKLYWLVTQNVDALHTKAGSRR--LTELHGCMDRVLCL 170
           +      +P   H+ +   +  G L    TQN+D L   AG  +  L E HG      C+
Sbjct: 100 ELYPGQFKPTICHYFMRLLKDKGLLLRCYTQNIDTLERIAGLEQEDLVEAHGTFYTSHCV 159

Query: 171 --DCGEQTPRGVLQERFQVLNPTWSAEAHGLAPDGDVFLSEEQVRSFQVPTCVQCGGHLK 228
              C  + P             +W                +E++ S   P C  C   +K
Sbjct: 160 SASCRHEYPL------------SW---------------MKEKIFSEVTPKCEDCQSLVK 192

Query: 229 PDVVFFGDTVNPDKVDFVHKRVKEADSLLVVGSSLQV 265
           PD+VFFG+++       +     + D LLV+G+SLQV
Sbjct: 193 PDIVFFGESLPARFFSCMQSDFLKVDLLLVMGTSLQV 229


>gi|215982798 sirtuin 1 isoform b [Homo sapiens]
          Length = 452

 Score = 57.0 bits (136), Expect = 2e-08
 Identities = 50/152 (32%), Positives = 73/152 (48%), Gaps = 34/152 (22%)

Query: 120 QPNPAHWALSTWEKLGKLYWLVTQNVDALHTKAGSRRLTELHGCMDRVLCLDCGEQTPRG 179
           QP+  H  ++  +K GKL    TQN+D L   AG +R+ + HG      CL C       
Sbjct: 27  QPSLCHKFIALSDKEGKLLRNYTQNIDTLEQVAGIQRIIQCHGSFATASCLIC------- 79

Query: 180 VLQERFQVLNPTWSAEAHGLAPDGDVFLSEEQVRSFQVPTCVQCGGH-----LKPDVVFF 234
               +++V       E    A  GD+F    QV    VP C +C        +KP++VFF
Sbjct: 80  ----KYKV-----DCE----AVRGDIF---NQV----VPRCPRCPADEPLAIMKPEIVFF 119

Query: 235 GDTVNPDKVDFVHKRVK-EADSLLVVGSSLQV 265
           G+ + P++     K  K E D L+V+GSSL+V
Sbjct: 120 GENL-PEQFHRAMKYDKDEVDLLIVIGSSLKV 150


>gi|190358526 hypothetical protein LOC54785 [Homo sapiens]
          Length = 357

 Score = 29.3 bits (64), Expect = 4.7
 Identities = 13/30 (43%), Positives = 20/30 (66%), Gaps = 1/30 (3%)

Query: 20  PSQPCSKASIGLFVPASPPLDPEKVKELQR 49
           P++PC  A      PA PP+DPE +++L+R
Sbjct: 238 PARPCP-APAPTPTPAIPPIDPEVLRDLER 266


>gi|196049380 3-hydroxy-3-methylglutaryl-Coenzyme A reductase
           isoform 2 [Homo sapiens]
          Length = 835

 Score = 28.9 bits (63), Expect = 6.2
 Identities = 24/75 (32%), Positives = 33/75 (44%), Gaps = 16/75 (21%)

Query: 1   MKMSFALTFRSAKGRWIANPS-----QPCSKASIGLFVPASPPLDPEK-----------V 44
           M MS  L    A  RWIA+PS        SK S+GL    S  ++P              
Sbjct: 258 MIMSLGLVLVHAHSRWIADPSPQNSTADTSKVSLGLDENVSKRIEPSVSLWQFYLSKMIS 317

Query: 45  KELQRFITLSKRLLV 59
            ++++ ITLS  LL+
Sbjct: 318 MDIEQVITLSLALLL 332


>gi|4557643 3-hydroxy-3-methylglutaryl-Coenzyme A reductase isoform
           1 [Homo sapiens]
          Length = 888

 Score = 28.9 bits (63), Expect = 6.2
 Identities = 24/75 (32%), Positives = 33/75 (44%), Gaps = 16/75 (21%)

Query: 1   MKMSFALTFRSAKGRWIANPS-----QPCSKASIGLFVPASPPLDPEK-----------V 44
           M MS  L    A  RWIA+PS        SK S+GL    S  ++P              
Sbjct: 258 MIMSLGLVLVHAHSRWIADPSPQNSTADTSKVSLGLDENVSKRIEPSVSLWQFYLSKMIS 317

Query: 45  KELQRFITLSKRLLV 59
            ++++ ITLS  LL+
Sbjct: 318 MDIEQVITLSLALLL 332


>gi|163965366 nascent polypeptide-associated complex alpha subunit
           isoform a [Homo sapiens]
          Length = 2078

 Score = 28.9 bits (63), Expect = 6.2
 Identities = 13/29 (44%), Positives = 19/29 (65%), Gaps = 1/29 (3%)

Query: 20  PSQPCSKASIGLFVPASPPL-DPEKVKEL 47
           P +P ++ +  L +P SPPL DPE +K L
Sbjct: 490 PKEPSTQVATTLRIPVSPPLPDPEDLKNL 518


>gi|110349719 titin isoform N2-A [Homo sapiens]
          Length = 33423

 Score = 28.5 bits (62), Expect = 8.1
 Identities = 16/71 (22%), Positives = 33/71 (46%), Gaps = 4/71 (5%)

Query: 20   PSQPCSKASIGLFVPASPPLDPEKVKELQRFITLSKRLLVMTGAGISTESGIPDYRSEKV 79
            P +P  +  I + V       P KV E+Q+ +   +++ ++T    S    +P+   +KV
Sbjct: 9348 PKKPVPEEKIPVPVAKKKEAPPAKVPEVQKGVVTEEKITIVTQREESPPPAVPEIPKKKV 9407

Query: 80   GLYARTDRRPI 90
                  +R+P+
Sbjct: 9408 ----PEERKPV 9414


>gi|164663805 methyltransferase like 7B [Homo sapiens]
          Length = 244

 Score = 28.5 bits (62), Expect = 8.1
 Identities = 16/31 (51%), Positives = 20/31 (64%), Gaps = 2/31 (6%)

Query: 162 GCMDRVLC--LDCGEQTPRGVLQERFQVLNP 190
           G MD V+C  + C  Q+PR VLQE  +VL P
Sbjct: 136 GSMDVVVCTLVLCSVQSPRKVLQEVRRVLRP 166


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.137    0.439 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,004,983
Number of Sequences: 37866
Number of extensions: 590204
Number of successful extensions: 1175
Number of sequences better than 10.0: 17
Number of HSP's better than 10.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 1140
Number of HSP's gapped (non-prelim): 23
length of query: 314
length of database: 18,247,518
effective HSP length: 102
effective length of query: 212
effective length of database: 14,385,186
effective search space: 3049659432
effective search space used: 3049659432
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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