HMGCR 29945

Name: HMGCR	Sequence: fasta or formatted (888aa)		NCBI GI: 4557643
Description: 3-hydroxy-3-methylglutaryl-Coenzyme A reductase isoform 1		Referenced in: Cholesterol Biosynthesis Common Drug Targets Pancreas and Insulin
Other entries for this name: alt prot [835aa] 3-hydroxy-3-methylglutaryl-Coenzyme A reductase isoform 2
Composition: Amino acid Percentage Count Longest homopolymer A alanine 7.7 68 2 C cysteine 3.2 28 2 D aspartate 2.9 26 1 E glutamate 7.1 63 4 F phenylalanine 3.6 32 2 G glycine 6.8 60 3 H histidine 1.6 14 1 I isoleucine 6.8 60 3 K lysine 4.6 41 2 L leucine 10.4 92 3 M methionine 3.7 33 2 N asparagine 4.8 43 2 P proline 4.2 37 1 Q glutamine 3.5 31 2 R arginine 4.8 43 2 S serine 8.0 71 2 T threonine 5.9 52 3 V valine 7.7 68 2 W tryptophan 0.8 7 1 Y tyrosine 2.1 19 1			Comparative genomics: Search single species RefSeq proteins at NCBI H. sapiens M. musculus D. rerio C. intestinalis S. purpuratus D. melanogaster C. elegans A. thaliana S. cerevisiae E. coli W3110 A. pernix K1 Search summary Figure data Additional searches of RefSeq proteins at NCBI All Eukaryotes Bacteria Archaea Viruses Primates Mammals Vertebrates
Related human proteins: Protein Relative score Description Self-match 1.000 3-hydroxy-3-methylglutaryl-Coenzyme A reductase isofo... HMGCR 0.870 3-hydroxy-3-methylglutaryl-Coenzyme A reductase iso... SCAP 0.026 SREBF chaperone protein NPC1 0.014 Niemann-Pick disease, type C1 precursor C6orf138 0.013 hypothetical protein LOC442213 PTCHD3 0.010 patched domain containing 3 PTCHD1 0.010 patched domain containing 1 CELSR1 0.005 cadherin EGF LAG seven-pass G-type receptor 1 RASAL3 0.003 RAS protein activator like 3 CAPZA3 0.003 capping protein alpha 3 LOC100128559 0.003 PREDICTED: hypothetical protein LOC100128559 0.003 PREDICTED: hypothetical protein LOC100128559 0.003 PREDICTED: hypothetical protein C20orf117 0.003 hypothetical protein LOC140710 OTUD6B 0.003 OTU domain containing 6B Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.