Guide to the Human Genome
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Name: APPL1 Sequence: fasta or formatted (709aa) NCBI GI: 6912242
Description:

adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1

Referenced in:

Rab

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.8         48           2
 C cysteine            1.7         12           1
 D aspartate           5.8         41           2
 E glutamate           8.7         62           2
 F phenylalanine       3.8         27           2
 G glycine             4.8         34           2
 H histidine           2.0         14           1
 I isoleucine          5.1         36           2
 K lysine              6.1         43           3
 L leucine             9.2         65           2
 M methionine          2.5         18           2
 N asparagine          4.2         30           2
 P proline             3.8         27           2
 Q glutamine           6.8         48           2
 R arginine            5.4         38           2
 S serine             10.0         71           3
 T threonine           5.6         40           1
 V valine              4.9         35           2
 W tryptophan          0.3          2           1
 Y tyrosine            2.5         18           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   adaptor protein, phosphotyrosine interaction, PH doma... 
APPL2                 0.476   adaptor protein, phosphotyrosine interaction, PH dom...
ACAP3                 0.062   ArfGAP with coiled-coil, ankyrin repeat and PH doma...
ACAP2                 0.059   centaurin, beta 2 
ARHGAP10              0.054   Rho GTPase activating protein 10 
ACAP1                 0.044   centaurin beta1 
FLJ32810              0.042   Rho-type GTPase-activating protein FLJ32810 
ARHGAP26              0.042   GTPase regulator associated with the focal adhesion...
ARHGAP26              0.042   GTPase regulator associated with the focal adhesion k...
OPHN1                 0.040   oligophrenin 1 
ASAP1                 0.030   development and differentiation enhancing factor 1 [...
ASAP2                 0.028   ArfGAP with SH3 domain, ankyrin repeat and PH domai...
ASAP2                 0.028   ArfGAP with SH3 domain, ankyrin repeat and PH domain ...
GULP1                 0.026   GULP, engulfment adaptor PTB domain containing 1 [Hom...
MKL2                  0.012   megakaryoblastic leukemia 2 protein 
MYH8                  0.010   myosin, heavy chain 8, skeletal muscle, perinatal [...
RGS12                 0.010   regulator of G-protein signalling 12 isoform 2 
RGS12                 0.010   regulator of G-protein signalling 12 isoform 1 [Homo...
ITSN1                 0.009   intersectin 1 isoform ITSN-s 
ITSN1                 0.009   intersectin 1 isoform ITSN-l 
CCDC30                0.009   coiled-coil domain containing 30 
BAT2D1                0.009   HBxAg transactivated protein 2 
MYH2                  0.009   myosin, heavy chain 2, skeletal muscle, adult [Homo...
MYH2                  0.009   myosin, heavy chain 2, skeletal muscle, adult [Homo...
SR140                 0.009   U2-associated SR140 protein 
RGAG4                 0.009   retrotransposon gag domain containing 4 
KTN1                  0.009   kinectin 1 isoform c 
MYH7                  0.009   myosin, heavy chain 7, cardiac muscle, beta 
MYH1                  0.009   myosin, heavy chain 1, skeletal muscle, adult [Homo...
CGN                   0.008   cingulin 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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