APPL2 23953

Name: APPL2	Sequence: fasta or formatted (664aa)		NCBI GI: 24586663
Description: adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2		Referenced in: Rab
Composition: Amino acid Percentage Count Longest homopolymer A alanine 8.1 54 3 C cysteine 1.4 9 1 D aspartate 5.1 34 4 E glutamate 9.3 62 2 F phenylalanine 3.8 25 2 G glycine 4.5 30 2 H histidine 1.4 9 1 I isoleucine 5.1 34 2 K lysine 5.6 37 3 L leucine 10.4 69 3 M methionine 3.3 22 2 N asparagine 5.3 35 2 P proline 3.8 25 1 Q glutamine 6.9 46 2 R arginine 4.4 29 2 S serine 7.2 48 2 T threonine 5.9 39 3 V valine 5.7 38 2 W tryptophan 0.3 2 1 Y tyrosine 2.6 17 2			Comparative genomics: Search single species RefSeq proteins at NCBI H. sapiens M. musculus D. rerio C. intestinalis S. purpuratus D. melanogaster C. elegans A. thaliana S. cerevisiae E. coli W3110 A. pernix K1 Search summary Figure data Additional searches of RefSeq proteins at NCBI All Eukaryotes Bacteria Archaea Viruses Primates Mammals Vertebrates
Related human proteins: Protein Relative score Description Self-match 1.000 adaptor protein, phosphotyrosine interaction, PH dom... APPL1 0.512 adaptor protein, phosphotyrosine interaction, PH doma... ACAP2 0.066 centaurin, beta 2 ACAP3 0.062 ArfGAP with coiled-coil, ankyrin repeat and PH doma... ARHGAP10 0.046 Rho GTPase activating protein 10 FLJ32810 0.046 Rho-type GTPase-activating protein FLJ32810 ARHGAP26 0.042 GTPase regulator associated with the focal adhesion... ARHGAP26 0.042 GTPase regulator associated with the focal adhesion k... ACAP1 0.036 centaurin beta1 OPHN1 0.032 oligophrenin 1 ASAP1 0.024 development and differentiation enhancing factor 1 [... ASAP2 0.024 ArfGAP with SH3 domain, ankyrin repeat and PH domai... ASAP2 0.024 ArfGAP with SH3 domain, ankyrin repeat and PH domain ... GULP1 0.017 GULP, engulfment adaptor PTB domain containing 1 [Hom... EEA1 0.013 early endosome antigen 1, 162kD DGKK 0.013 diacylglycerol kinase kappa ASAP3 0.013 ArfGAP with SH3 domain, ankyrin repeat and PH domai... ASAP3 0.013 ArfGAP with SH3 domain, ankyrin repeat and PH domain... GCOM1 0.010 GRINL1A combined protein isoform 2 GCOM1 0.010 GRINL1A combined protein isoform 1 GCOM1 0.010 GRINL1A combined protein isoform 8 GCOM1 0.010 GRINL1A upstream protein isoform 7 GOLGB1 0.009 golgi autoantigen, golgin subfamily b, macrogolgin ... UTP14A 0.009 UTP14, U3 small nucleolar ribonucleoprotein, homolog... MTHFD2 0.008 methylenetetrahydrofolate dehydrogenase 2 precursor ... FGD4 0.008 FYVE, RhoGEF and PH domain containing 4 DGKD 0.008 diacylglycerol kinase, delta 130kDa isoform 2 MAPK8IP1 0.007 mitogen-activated protein kinase 8 interacting protei... PLEKHH2 0.007 pleckstrin homology domain containing, family H (wi... CCDC102A 0.007 coiled-coil domain containing 102A Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.