Guide to the Human Genome
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Search of human proteins with 68448537

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|68448537 CD74 antigen isoform c [Homo sapiens]
         (160 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|68448537 CD74 antigen isoform c [Homo sapiens]                     330   3e-91
gi|68448544 CD74 antigen isoform a [Homo sapiens]                     298   1e-81
gi|10835071 CD74 antigen isoform b [Homo sapiens]                     298   1e-81
gi|88703045 proline rich 11 [Homo sapiens]                             30   0.68 
gi|169171347 PREDICTED: hypothetical protein [Homo sapiens]            29   2.0  
gi|169172209 PREDICTED: hypothetical protein [Homo sapiens]            29   2.0  
gi|169170953 PREDICTED: hypothetical protein [Homo sapiens]            29   2.0  
gi|239508753 PREDICTED: hypothetical protein [Homo sapiens]            29   2.0  
gi|22027480 pogo transposable element with KRAB domain [Homo sap...    28   2.6  
gi|18034692 CDW92 antigen [Homo sapiens]                               28   2.6  
gi|210032580 SET domain containing 1B [Homo sapiens]                   28   3.4  
gi|33359221 dyslexia susceptibility 2-like [Homo sapiens]              28   4.4  
gi|55749531 splicing factor 3B subunit 2 [Homo sapiens]                28   4.4  
gi|222080070 pleckstrin homology domain-containing family G memb...    27   5.7  
gi|222080068 pleckstrin homology domain-containing family G memb...    27   5.7  
gi|222080066 pleckstrin homology domain-containing family G memb...    27   5.7  
gi|24308215 retrotransposon gag domain containing 1 [Homo sapiens]     27   5.7  
gi|105990532 apolipoprotein B precursor [Homo sapiens]                 27   7.5  
gi|110556636 tankyrase 1-binding protein 1 [Homo sapiens]              27   7.5  
gi|93277099 solute carrier organic anion transporter family, mem...    27   9.8  

>gi|68448537 CD74 antigen isoform c [Homo sapiens]
          Length = 160

 Score =  330 bits (846), Expect = 3e-91
 Identities = 160/160 (100%), Positives = 160/160 (100%)

Query: 1   MHRRRSRSCREDQKPVMDDQRDLISNNEQLPMLGRRPGAPESKCSRGALYTGFSILVTLL 60
           MHRRRSRSCREDQKPVMDDQRDLISNNEQLPMLGRRPGAPESKCSRGALYTGFSILVTLL
Sbjct: 1   MHRRRSRSCREDQKPVMDDQRDLISNNEQLPMLGRRPGAPESKCSRGALYTGFSILVTLL 60

Query: 61  LAGQATTAYFLYQQQGRLDKLTVTSQNLQLENLRMKLPKPPKPVSKMRMATPLLMQALPM 120
           LAGQATTAYFLYQQQGRLDKLTVTSQNLQLENLRMKLPKPPKPVSKMRMATPLLMQALPM
Sbjct: 61  LAGQATTAYFLYQQQGRLDKLTVTSQNLQLENLRMKLPKPPKPVSKMRMATPLLMQALPM 120

Query: 121 GALPQGPMQNATKYGNMTEDHVMHLLQSHWNWRTRLLGWV 160
           GALPQGPMQNATKYGNMTEDHVMHLLQSHWNWRTRLLGWV
Sbjct: 121 GALPQGPMQNATKYGNMTEDHVMHLLQSHWNWRTRLLGWV 160


>gi|68448544 CD74 antigen isoform a [Homo sapiens]
          Length = 296

 Score =  298 bits (763), Expect = 1e-81
 Identities = 147/148 (99%), Positives = 148/148 (100%)

Query: 1   MHRRRSRSCREDQKPVMDDQRDLISNNEQLPMLGRRPGAPESKCSRGALYTGFSILVTLL 60
           MHRRRSRSCREDQKPVMDDQRDLISNNEQLPMLGRRPGAPESKCSRGALYTGFSILVTLL
Sbjct: 1   MHRRRSRSCREDQKPVMDDQRDLISNNEQLPMLGRRPGAPESKCSRGALYTGFSILVTLL 60

Query: 61  LAGQATTAYFLYQQQGRLDKLTVTSQNLQLENLRMKLPKPPKPVSKMRMATPLLMQALPM 120
           LAGQATTAYFLYQQQGRLDKLTVTSQNLQLENLRMKLPKPPKPVSKMRMATPLLMQALPM
Sbjct: 61  LAGQATTAYFLYQQQGRLDKLTVTSQNLQLENLRMKLPKPPKPVSKMRMATPLLMQALPM 120

Query: 121 GALPQGPMQNATKYGNMTEDHVMHLLQS 148
           GALPQGPMQNATKYGNMTEDHVMHLLQ+
Sbjct: 121 GALPQGPMQNATKYGNMTEDHVMHLLQN 148


>gi|10835071 CD74 antigen isoform b [Homo sapiens]
          Length = 232

 Score =  298 bits (763), Expect = 1e-81
 Identities = 147/148 (99%), Positives = 148/148 (100%)

Query: 1   MHRRRSRSCREDQKPVMDDQRDLISNNEQLPMLGRRPGAPESKCSRGALYTGFSILVTLL 60
           MHRRRSRSCREDQKPVMDDQRDLISNNEQLPMLGRRPGAPESKCSRGALYTGFSILVTLL
Sbjct: 1   MHRRRSRSCREDQKPVMDDQRDLISNNEQLPMLGRRPGAPESKCSRGALYTGFSILVTLL 60

Query: 61  LAGQATTAYFLYQQQGRLDKLTVTSQNLQLENLRMKLPKPPKPVSKMRMATPLLMQALPM 120
           LAGQATTAYFLYQQQGRLDKLTVTSQNLQLENLRMKLPKPPKPVSKMRMATPLLMQALPM
Sbjct: 61  LAGQATTAYFLYQQQGRLDKLTVTSQNLQLENLRMKLPKPPKPVSKMRMATPLLMQALPM 120

Query: 121 GALPQGPMQNATKYGNMTEDHVMHLLQS 148
           GALPQGPMQNATKYGNMTEDHVMHLLQ+
Sbjct: 121 GALPQGPMQNATKYGNMTEDHVMHLLQN 148


>gi|88703045 proline rich 11 [Homo sapiens]
          Length = 360

 Score = 30.4 bits (67), Expect = 0.68
 Identities = 16/38 (42%), Positives = 22/38 (57%), Gaps = 1/38 (2%)

Query: 97  LPKPPKPVSKMRMATPLLMQALPMGALPQ-GPMQNATK 133
           LP PP P++ + +  P L +AL  G L + GPMQ   K
Sbjct: 193 LPPPPPPLAPVLLRKPSLAKALQAGPLKKDGPMQITVK 230


>gi|169171347 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1128

 Score = 28.9 bits (63), Expect = 2.0
 Identities = 17/56 (30%), Positives = 26/56 (46%), Gaps = 1/56 (1%)

Query: 87  NLQLENLRMKLP-KPPKPVSKMRMATPLLMQALPMGALPQGPMQNATKYGNMTEDH 141
           +L+LE+LR ++P +PP P+  + +   L    LP  A    P Q     G     H
Sbjct: 576 HLELESLRERVPCEPPPPLPPLLLGVSLPPFGLPTSASEPDPAQRVQSTGVYRHRH 631


>gi|169172209 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 801

 Score = 28.9 bits (63), Expect = 2.0
 Identities = 17/56 (30%), Positives = 26/56 (46%), Gaps = 1/56 (1%)

Query: 87  NLQLENLRMKLP-KPPKPVSKMRMATPLLMQALPMGALPQGPMQNATKYGNMTEDH 141
           +L+LE+LR ++P +PP P+  + +   L    LP  A    P Q     G     H
Sbjct: 249 HLELESLRERVPCEPPPPLPPLLLGVSLPPFGLPTSASEPDPAQRVQSTGVYRHRH 304


>gi|169170953 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 801

 Score = 28.9 bits (63), Expect = 2.0
 Identities = 17/56 (30%), Positives = 26/56 (46%), Gaps = 1/56 (1%)

Query: 87  NLQLENLRMKLP-KPPKPVSKMRMATPLLMQALPMGALPQGPMQNATKYGNMTEDH 141
           +L+LE+LR ++P +PP P+  + +   L    LP  A    P Q     G     H
Sbjct: 249 HLELESLRERVPCEPPPPLPPLLLGVSLPPFGLPTSASEPDPAQRVQSTGVYRHRH 304


>gi|239508753 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 801

 Score = 28.9 bits (63), Expect = 2.0
 Identities = 17/56 (30%), Positives = 26/56 (46%), Gaps = 1/56 (1%)

Query: 87  NLQLENLRMKLP-KPPKPVSKMRMATPLLMQALPMGALPQGPMQNATKYGNMTEDH 141
           +L+LE+LR ++P +PP P+  + +   L    LP  A    P Q     G     H
Sbjct: 249 HLELESLRERVPCEPPPPLPPLLLGVSLPPFGLPTSASEPDPAQRVQSTGVYRHRH 304


>gi|22027480 pogo transposable element with KRAB domain [Homo
           sapiens]
          Length = 609

 Score = 28.5 bits (62), Expect = 2.6
 Identities = 14/37 (37%), Positives = 18/37 (48%)

Query: 118 LPMGALPQGPMQNATKYGNMTEDHVMHLLQSHWNWRT 154
           +P G  P G      +YG MTED +   L+  W  RT
Sbjct: 422 IPPGKFPSGMEIRCHRYGWMTEDLMQDWLEVVWRRRT 458


>gi|18034692 CDW92 antigen [Homo sapiens]
          Length = 657

 Score = 28.5 bits (62), Expect = 2.6
 Identities = 19/46 (41%), Positives = 26/46 (56%), Gaps = 2/46 (4%)

Query: 54  SILVTLLLAGQATTAYFLYQQQGRLDKLTVTSQNLQL--ENLRMKL 97
           +ILV L   G     ++LY +Q R  K TVT + LQ+  +NLR  L
Sbjct: 245 TILVILGSLGGTGVLWWLYAKQRRSPKETVTPEQLQIAEDNLRALL 290


>gi|210032580 SET domain containing 1B [Homo sapiens]
          Length = 1923

 Score = 28.1 bits (61), Expect = 3.4
 Identities = 18/56 (32%), Positives = 25/56 (44%), Gaps = 5/56 (8%)

Query: 98   PKPPKPVSKMRMATPLLMQALPMGALPQGPMQNATKYGNMTEDHVMHLLQSHWNWR 153
            P PP PV   ++    L    P  A+P GP         +TE++ M L +S   WR
Sbjct: 1550 PPPPPPVEPTKLPFKELDNQWPSEAIPPGPRGR----DEVTEEY-MELAKSRGPWR 1600


>gi|33359221 dyslexia susceptibility 2-like [Homo sapiens]
          Length = 1049

 Score = 27.7 bits (60), Expect = 4.4
 Identities = 12/24 (50%), Positives = 13/24 (54%)

Query: 129 QNATKYGNMTEDHVMHLLQSHWNW 152
           Q A   G + ED V HLL   WNW
Sbjct: 135 QTADDLGFLPEDDVPHLLGLGWNW 158


>gi|55749531 splicing factor 3B subunit 2 [Homo sapiens]
          Length = 895

 Score = 27.7 bits (60), Expect = 4.4
 Identities = 16/58 (27%), Positives = 29/58 (50%), Gaps = 4/58 (6%)

Query: 71  LYQQQGRLDKLTVTSQNLQLENLRMKLPKPPKPVSKMRMATPLLMQALPMGALPQGPM 128
           L +QQ R   L    +  ++  +   +P+PP+ + ++ + TPL     P  A P GP+
Sbjct: 177 LLEQQKRAAVLLEQERQQEIAKMGTPVPRPPQDMGQIGVRTPL----GPRVAAPVGPV 230


>gi|222080070 pleckstrin homology domain-containing family G member
           6 isoform b [Homo sapiens]
          Length = 758

 Score = 27.3 bits (59), Expect = 5.7
 Identities = 22/76 (28%), Positives = 37/76 (48%), Gaps = 3/76 (3%)

Query: 51  TGFSILVTLLLAGQATTAYFLYQQQGRLDKLTVTSQNLQLENLRMKLPKPPKPVSKMRMA 110
           +G+  L+     G  +    L Q+  R D   +T   L+L ++ ++ P PP P +  R +
Sbjct: 556 SGYGTLIPGTPTGSRSPLSRLRQRALRRDP-RLTFSTLELRDIPLR-PHPPDPQAPQRRS 613

Query: 111 TPLLMQA-LPMGALPQ 125
            P L +  L  G+LPQ
Sbjct: 614 APELPEGILKGGSLPQ 629


>gi|222080068 pleckstrin homology domain-containing family G member
           6 isoform a [Homo sapiens]
          Length = 790

 Score = 27.3 bits (59), Expect = 5.7
 Identities = 22/76 (28%), Positives = 37/76 (48%), Gaps = 3/76 (3%)

Query: 51  TGFSILVTLLLAGQATTAYFLYQQQGRLDKLTVTSQNLQLENLRMKLPKPPKPVSKMRMA 110
           +G+  L+     G  +    L Q+  R D   +T   L+L ++ ++ P PP P +  R +
Sbjct: 588 SGYGTLIPGTPTGSRSPLSRLRQRALRRDP-RLTFSTLELRDIPLR-PHPPDPQAPQRRS 645

Query: 111 TPLLMQA-LPMGALPQ 125
            P L +  L  G+LPQ
Sbjct: 646 APELPEGILKGGSLPQ 661


>gi|222080066 pleckstrin homology domain-containing family G member
           6 isoform a [Homo sapiens]
          Length = 790

 Score = 27.3 bits (59), Expect = 5.7
 Identities = 22/76 (28%), Positives = 37/76 (48%), Gaps = 3/76 (3%)

Query: 51  TGFSILVTLLLAGQATTAYFLYQQQGRLDKLTVTSQNLQLENLRMKLPKPPKPVSKMRMA 110
           +G+  L+     G  +    L Q+  R D   +T   L+L ++ ++ P PP P +  R +
Sbjct: 588 SGYGTLIPGTPTGSRSPLSRLRQRALRRDP-RLTFSTLELRDIPLR-PHPPDPQAPQRRS 645

Query: 111 TPLLMQA-LPMGALPQ 125
            P L +  L  G+LPQ
Sbjct: 646 APELPEGILKGGSLPQ 661


>gi|24308215 retrotransposon gag domain containing 1 [Homo sapiens]
          Length = 1388

 Score = 27.3 bits (59), Expect = 5.7
 Identities = 12/28 (42%), Positives = 14/28 (50%)

Query: 101 PKPVSKMRMATPLLMQALPMGALPQGPM 128
           PKP       +P LM ALP G +P   M
Sbjct: 337 PKPAPDAEAMSPALMTALPSGVMPTQTM 364


>gi|105990532 apolipoprotein B precursor [Homo sapiens]
          Length = 4563

 Score = 26.9 bits (58), Expect = 7.5
 Identities = 18/58 (31%), Positives = 29/58 (50%), Gaps = 10/58 (17%)

Query: 78  LDKLTVTSQNLQLENLRMKLPKPPKPVSK----------MRMATPLLMQALPMGALPQ 125
           L KLT++ QN+Q  NL  KL    + +S           + +++P+ +QAL     PQ
Sbjct: 332 LKKLTISEQNIQRANLFNKLVTELRGLSDEAVTSLLPQLIEVSSPITLQALVQCGQPQ 389


>gi|110556636 tankyrase 1-binding protein 1 [Homo sapiens]
          Length = 1729

 Score = 26.9 bits (58), Expect = 7.5
 Identities = 23/92 (25%), Positives = 36/92 (39%), Gaps = 13/92 (14%)

Query: 31  PMLGR-RPGAPESKCSRGALYTGFSILVTLLLAGQATTAYFLYQQQGRLDKLTVTSQNLQ 89
           P+LG+ +P AP+  C            V    A +   A  + ++   L +   T    +
Sbjct: 617 PVLGQEQPAAPDQPC------------VLFADAPEPGQALPVEEEAVTLARAETTQARTE 664

Query: 90  LENLRMKLPKPPKPVSKMRMATPLLMQALPMG 121
            ++L    P+PP P S  R    LL    P G
Sbjct: 665 AQDLCRASPEPPGPESSSRWLDDLLASPPPSG 696


>gi|93277099 solute carrier organic anion transporter family, member
           6A1 [Homo sapiens]
          Length = 719

 Score = 26.6 bits (57), Expect = 9.8
 Identities = 23/94 (24%), Positives = 42/94 (44%), Gaps = 1/94 (1%)

Query: 23  LISNNEQLPMLGRRPGAPESKCSRGALYTGFSILVTLLLAGQATTAYFLYQQQGRLDKLT 82
           LI+ + +   +  RPG  ++KC +  L+  F I  TL+ +G +     L   +   DKL 
Sbjct: 554 LITADAEGDFIDARPGKCDAKCYKLPLFIAF-IFSTLIFSGFSGVPIVLAMTRVVPDKLR 612

Query: 83  VTSQNLQLENLRMKLPKPPKPVSKMRMATPLLMQ 116
             +  +    LR+    P   + KM   T  +++
Sbjct: 613 SLALGVSYVILRIFGTIPGPSIFKMSGETSCILR 646


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.133    0.407 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,701,248
Number of Sequences: 37866
Number of extensions: 290050
Number of successful extensions: 952
Number of sequences better than 10.0: 20
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 13
Number of HSP's that attempted gapping in prelim test: 938
Number of HSP's gapped (non-prelim): 23
length of query: 160
length of database: 18,247,518
effective HSP length: 94
effective length of query: 66
effective length of database: 14,688,114
effective search space: 969415524
effective search space used: 969415524
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 57 (26.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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