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Search of human proteins with 67191027
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|67191027 integrin alpha 4 precursor [Homo sapiens]
(1032 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|67191027 integrin alpha 4 precursor [Homo sapiens] 2090 0.0
gi|52485941 integrin, alpha 9 precursor [Homo sapiens] 795 0.0
gi|49170034 integrin, alpha 8 [Homo sapiens] 312 1e-84
gi|4504763 integrin alpha-V isoform 1 precursor [Homo sapiens] 296 9e-80
gi|56237029 integrin alpha 5 precursor [Homo sapiens] 292 1e-78
gi|119395742 integrin alpha chain, alpha 6 isoform b precursor [... 286 9e-77
gi|119395740 integrin alpha chain, alpha 6 isoform a precursor [... 285 2e-76
gi|223468595 integrin alpha-V isoform 2 [Homo sapiens] 272 1e-72
gi|223468597 integrin alpha-V isoform 3 precursor [Homo sapiens] 263 8e-70
gi|222418611 integrin alpha 7 isoform 2 precursor [Homo sapiens] 257 3e-68
gi|222418613 integrin alpha 7 isoform 1 precursor [Homo sapiens] 248 2e-65
gi|88758615 integrin alpha 2b preproprotein [Homo sapiens] 248 2e-65
gi|4504747 integrin alpha 3 isoform a precursor [Homo sapiens] 245 2e-64
gi|6006011 integrin alpha 3 isoform b precursor [Homo sapiens] 245 2e-64
gi|34452173 integrin alpha X precursor [Homo sapiens] 233 5e-61
gi|31657142 integrin, alpha 1 precursor [Homo sapiens] 233 9e-61
gi|62548866 integrin, alpha D precursor [Homo sapiens] 216 1e-55
gi|224831239 integrin alpha M isoform 1 precursor [Homo sapiens] 212 1e-54
gi|88501734 integrin alpha M isoform 2 precursor [Homo sapiens] 212 2e-54
gi|38569398 integrin, alpha 10 precursor [Homo sapiens] 209 1e-53
gi|52485853 integrin, alpha 11 precursor [Homo sapiens] 203 6e-52
gi|116295258 integrin alpha 2 precursor [Homo sapiens] 201 4e-51
gi|222418615 integrin alpha 7 isoform 3 [Homo sapiens] 199 1e-50
gi|167466217 integrin alpha L isoform b precursor [Homo sapiens] 198 2e-50
gi|167466215 integrin alpha L isoform a precursor [Homo sapiens] 195 2e-49
gi|148728188 integrin, alpha E precursor [Homo sapiens] 187 3e-47
gi|29171717 glycosylphosphatidylinositol specific phospholipase ... 52 3e-06
gi|239751058 PREDICTED: hypothetical protein XP_002347690 [Homo ... 49 3e-05
gi|126032348 hect domain and RLD 2 [Homo sapiens] 32 4.0
gi|156938343 talin 2 [Homo sapiens] 30 9.0
>gi|67191027 integrin alpha 4 precursor [Homo sapiens]
Length = 1032
Score = 2090 bits (5415), Expect = 0.0
Identities = 1032/1032 (100%), Positives = 1032/1032 (100%)
Query: 1 MAWEARREPGPRRAAVRETVMLLLCLGVPTGRPYNVDTESALLYQGPHNTLFGYSVVLHS 60
MAWEARREPGPRRAAVRETVMLLLCLGVPTGRPYNVDTESALLYQGPHNTLFGYSVVLHS
Sbjct: 1 MAWEARREPGPRRAAVRETVMLLLCLGVPTGRPYNVDTESALLYQGPHNTLFGYSVVLHS 60
Query: 61 HGANRWLLVGAPTANWLANASVINPGAIYRCRIGKNPGQTCEQLQLGSPNGEPCGKTCLE 120
HGANRWLLVGAPTANWLANASVINPGAIYRCRIGKNPGQTCEQLQLGSPNGEPCGKTCLE
Sbjct: 61 HGANRWLLVGAPTANWLANASVINPGAIYRCRIGKNPGQTCEQLQLGSPNGEPCGKTCLE 120
Query: 121 ERDNQWLGVTLSRQPGENGSIVTCGHRWKNIFYIKNENKLPTGGCYGVPPDLRTELSKRI 180
ERDNQWLGVTLSRQPGENGSIVTCGHRWKNIFYIKNENKLPTGGCYGVPPDLRTELSKRI
Sbjct: 121 ERDNQWLGVTLSRQPGENGSIVTCGHRWKNIFYIKNENKLPTGGCYGVPPDLRTELSKRI 180
Query: 181 APCYQDYVKKFGENFASCQAGISSFYTKDLIVMGAPGSSYWTGSLFVYNITTNKYKAFLD 240
APCYQDYVKKFGENFASCQAGISSFYTKDLIVMGAPGSSYWTGSLFVYNITTNKYKAFLD
Sbjct: 181 APCYQDYVKKFGENFASCQAGISSFYTKDLIVMGAPGSSYWTGSLFVYNITTNKYKAFLD 240
Query: 241 KQNQVKFGSYLGYSVGAGHFRSQHTTEVVGGAPQHEQIGKAYIFSIDEKELNILHEMKGK 300
KQNQVKFGSYLGYSVGAGHFRSQHTTEVVGGAPQHEQIGKAYIFSIDEKELNILHEMKGK
Sbjct: 241 KQNQVKFGSYLGYSVGAGHFRSQHTTEVVGGAPQHEQIGKAYIFSIDEKELNILHEMKGK 300
Query: 301 KLGSYFGASVCAVDLNADGFSDLLVGAPMQSTIREEGRVFVYINSGSGAVMNAMETNLVG 360
KLGSYFGASVCAVDLNADGFSDLLVGAPMQSTIREEGRVFVYINSGSGAVMNAMETNLVG
Sbjct: 301 KLGSYFGASVCAVDLNADGFSDLLVGAPMQSTIREEGRVFVYINSGSGAVMNAMETNLVG 360
Query: 361 SDKYAARFGESIVNLGDIDNDGFEDVAIGAPQEDDLQGAIYIYNGRADGISSTFSQRIEG 420
SDKYAARFGESIVNLGDIDNDGFEDVAIGAPQEDDLQGAIYIYNGRADGISSTFSQRIEG
Sbjct: 361 SDKYAARFGESIVNLGDIDNDGFEDVAIGAPQEDDLQGAIYIYNGRADGISSTFSQRIEG 420
Query: 421 LQISKSLSMFGQSISGQIDADNNGYVDVAVGAFRSDSAVLLRTRPVVIVDASLSHPESVN 480
LQISKSLSMFGQSISGQIDADNNGYVDVAVGAFRSDSAVLLRTRPVVIVDASLSHPESVN
Sbjct: 421 LQISKSLSMFGQSISGQIDADNNGYVDVAVGAFRSDSAVLLRTRPVVIVDASLSHPESVN 480
Query: 481 RTKFDCVENGWPSVCIDLTLCFSYKGKEVPGYIVLFYNMSLDVNRKAESPPRFYFSSNGT 540
RTKFDCVENGWPSVCIDLTLCFSYKGKEVPGYIVLFYNMSLDVNRKAESPPRFYFSSNGT
Sbjct: 481 RTKFDCVENGWPSVCIDLTLCFSYKGKEVPGYIVLFYNMSLDVNRKAESPPRFYFSSNGT 540
Query: 541 SDVITGSIQVSSREANCRTHQAFMRKDVRDILTPIQIEAAYHLGPHVISKRSTEEFPPLQ 600
SDVITGSIQVSSREANCRTHQAFMRKDVRDILTPIQIEAAYHLGPHVISKRSTEEFPPLQ
Sbjct: 541 SDVITGSIQVSSREANCRTHQAFMRKDVRDILTPIQIEAAYHLGPHVISKRSTEEFPPLQ 600
Query: 601 PILQQKKEKDIMKKTINFARFCAHENCSADLQVSAKIGFLKPHENKTYLAVGSMKTLMLN 660
PILQQKKEKDIMKKTINFARFCAHENCSADLQVSAKIGFLKPHENKTYLAVGSMKTLMLN
Sbjct: 601 PILQQKKEKDIMKKTINFARFCAHENCSADLQVSAKIGFLKPHENKTYLAVGSMKTLMLN 660
Query: 661 VSLFNAGDDAYETTLHVKLPVGLYFIKILELEEKQINCEVTDNSGVVQLDCSIGYIYVDH 720
VSLFNAGDDAYETTLHVKLPVGLYFIKILELEEKQINCEVTDNSGVVQLDCSIGYIYVDH
Sbjct: 661 VSLFNAGDDAYETTLHVKLPVGLYFIKILELEEKQINCEVTDNSGVVQLDCSIGYIYVDH 720
Query: 721 LSRIDISFLLDVSSLSRAEEDLSITVHATCENEEEMDNLKHSRVTVAIPLKYEVKLTVHG 780
LSRIDISFLLDVSSLSRAEEDLSITVHATCENEEEMDNLKHSRVTVAIPLKYEVKLTVHG
Sbjct: 721 LSRIDISFLLDVSSLSRAEEDLSITVHATCENEEEMDNLKHSRVTVAIPLKYEVKLTVHG 780
Query: 781 FVNPTSFVYGSNDENEPETCMVEKMNLTFHVINTGNSMAPNVSVEIMVPNSFSPQTDKLF 840
FVNPTSFVYGSNDENEPETCMVEKMNLTFHVINTGNSMAPNVSVEIMVPNSFSPQTDKLF
Sbjct: 781 FVNPTSFVYGSNDENEPETCMVEKMNLTFHVINTGNSMAPNVSVEIMVPNSFSPQTDKLF 840
Query: 841 NILDVQTTTGECHFENYQRVCALEQQKSAMQTLKGIVRFLSKTDKRLLYCIKADPHCLNF 900
NILDVQTTTGECHFENYQRVCALEQQKSAMQTLKGIVRFLSKTDKRLLYCIKADPHCLNF
Sbjct: 841 NILDVQTTTGECHFENYQRVCALEQQKSAMQTLKGIVRFLSKTDKRLLYCIKADPHCLNF 900
Query: 901 LCNFGKMESGKEASVHIQLEGRPSILEMDETSALKFEIRATGFPEPNPRVIELNKDENVA 960
LCNFGKMESGKEASVHIQLEGRPSILEMDETSALKFEIRATGFPEPNPRVIELNKDENVA
Sbjct: 901 LCNFGKMESGKEASVHIQLEGRPSILEMDETSALKFEIRATGFPEPNPRVIELNKDENVA 960
Query: 961 HVLLEGLHHQRPKRYFTIVIISSSLLLGLIVLLLISYVMWKAGFFKRQYKSILQEENRRD 1020
HVLLEGLHHQRPKRYFTIVIISSSLLLGLIVLLLISYVMWKAGFFKRQYKSILQEENRRD
Sbjct: 961 HVLLEGLHHQRPKRYFTIVIISSSLLLGLIVLLLISYVMWKAGFFKRQYKSILQEENRRD 1020
Query: 1021 SWSYINSKSNDD 1032
SWSYINSKSNDD
Sbjct: 1021 SWSYINSKSNDD 1032
>gi|52485941 integrin, alpha 9 precursor [Homo sapiens]
Length = 1035
Score = 795 bits (2054), Expect = 0.0
Identities = 432/1036 (41%), Positives = 632/1036 (61%), Gaps = 32/1036 (3%)
Query: 11 PRRAA-VRETVMLLLCLGVPTGRPYNVDTESALLYQGPHNTLFGYSVVLHSHGANRWLLV 69
PR A +R ++ L+ G+P G YN+D + + +QGP ++ FGY+V+ H H RW+LV
Sbjct: 7 PRGAGRLRALLLALVVAGIPAGA-YNLDPQRPVHFQGPADSFFGYAVLEHFHDNTRWVLV 65
Query: 70 GAPTANWLANASVINPGAIYRCRIGKNPGQTCEQLQL--GSPNGEPCGKTCLEERDNQWL 127
GAP A+ + SV +PGA+++CR+ NP + C +L + G G CGKTC E+RD++W+
Sbjct: 66 GAPKADSKYSPSVKSPGAVFKCRVHTNPDRRCTELDMARGKNRGTSCGKTCREDRDDEWM 125
Query: 128 GVTLSRQPGENGSIVTCGHRWKNIFYIKNENKLPTGGCYGVPPDLRTELSKRIAPCYQDY 187
GV+L+RQP +G ++ C HRWKNI+Y + ++ LP G CY +P +L+ + + + PCY++Y
Sbjct: 126 GVSLARQPKADGRVLACAHRWKNIYY-EADHILPHGFCYIIPSNLQAK-GRTLIPCYEEY 183
Query: 188 VKKFGENFASCQAGISSFYTKDLIVMGAPGSSYWTGSLFVYNITTNKYKAFLDKQNQVKF 247
KK+GE SCQAGI+ F+T++L+VMGAPGS YW G++ V N+T N Y D+ +
Sbjct: 184 KKKYGEEHGSCQAGIAGFFTEELVVMGAPGSFYWAGTIKVLNLTDNTYLKLNDEVIMNRR 243
Query: 248 GSYLGYSVGAGHFRSQHTTEVVGGAPQHEQIGKAYIFSIDEKELNILH--EMKGKKLGSY 305
+YLGY+V AGHF T +VVGGAPQ + IGK YIF D + ++ + GKK+GSY
Sbjct: 244 YTYLGYAVTAGHFSHPSTIDVVGGAPQDKGIGKVYIFRADRRSGTLIKIFQASGKKMGSY 303
Query: 306 FGASVCAVDLNADGFSDLLVGAPMQSTIREEGRVFVYINSGSGAVMNAMETNLVGSDKYA 365
FG+S+CAVDLN DG SDLLVGAPM S IR+EG+V VYIN G+GA+ + L G Y
Sbjct: 304 FGSSLCAVDLNGDGLSDLLVGAPMFSEIRDEGQVTVYINRGNGALEEQLA--LTGDGAYN 361
Query: 366 ARFGESIVNLGDIDNDGFEDVAIGAPQEDDLQGAIYIYNGRADGISSTFSQRIEGLQISK 425
A FGESI +L D+DNDGF DVAIGAP+EDD GA+YIY+G A GI +S ++ G +I+
Sbjct: 362 AHFGESIASLDDLDNDGFPDVAIGAPKEDDFAGAVYIYHGDAGGIVPQYSMKLSGQKINP 421
Query: 426 SLSMFGQSISGQIDADNNGYVDVAVGAFRSDSAVLLRTRPVVIVDASLSHPESVNRTKFD 485
L MFGQSISG ID D NGY DV VGAF SDS VLLR RPV+ VD S+ P S+N T
Sbjct: 422 VLRMFGQSISGGIDMDGNGYPDVTVGAFMSDSVVLLRARPVITVDVSIFLPGSINITAPQ 481
Query: 486 CVENGWPSVCIDLTLCFSYKGKEVPGYIVLFYNMSLDVNRKAESP-PRFYFSSNG-TSDV 543
C + P C+++T CFS+ GK VPG I L Y + DV +K + PR YF G T
Sbjct: 482 CHDGQQPVNCLNVTTCFSFHGKHVPGEIGLNYVLMADVAKKEKGQMPRVYFVLLGETMGQ 541
Query: 544 ITGSIQVSSREANCRTHQAFMRKDVRDILTPIQIEAAYHLGPHVISKRSTEEFPPLQPIL 603
+T +Q++ E CR + A +++ V+D+++PI EAAY L HV + E PPL P+L
Sbjct: 542 VTEKLQLTYMEETCRHYVAHVKRRVQDVISPIVFEAAYSLSEHVTGEEE-RELPPLTPVL 600
Query: 604 QQKKEKDIMKKTIN-FARFCAHENCSADLQVSAKIGFLKPHENKTYLAVGSMKTLMLNVS 662
+ KK + I +K F R C E+C+ADLQ+ K+ E YLA+G++K + LN+S
Sbjct: 601 RWKKGQKIAQKNQTVFERNCRSEDCAADLQLQGKLLLSSMDEKTLYLALGAVKNISLNIS 660
Query: 663 LFNAGDDAYETTLHVKLPVGLYFIKILELEEKQINCEVTDNSGVVQLDCSIGYIYVDHLS 722
+ N GDDAY+ + + L+FI + + EE I+CE+ ++ L CS+G+ ++ S
Sbjct: 661 ISNLGDDAYDANVSFNVSRELFFINMWQKEEMGISCELLESD---FLKCSVGFPFMRSKS 717
Query: 723 RIDISFLLDVSSLSRAEEDLSITVHATCENEEEMDNLKHSRVTVAIPLKYEVKLTVHGFV 782
+ + S + D S LS EE LS V A N E ++L + + + +PL +EV ++ G +
Sbjct: 718 KYEFSVIFDTSHLSGEEEVLSFIVTAQSGNTERSESLHDNTLVLMVPLMHEVDTSITGIM 777
Query: 783 NPTSFVYGSNDEN------EPETCMVEKMNLTFHVINTGNSMAPNVSVEIMVPNSFSPQT 836
+PTSFVYG + + + C + +N+T V NTG S P SV I PN S
Sbjct: 778 SPTSFVYGESVDAANFIQLDDLECHFQPINITLQVYNTGPSTLPGSSVSISFPNRLSSGG 837
Query: 837 DKLFNILD--VQTTTGECHFENYQRVCALEQQKSAMQTLKGIVRFLSKTDKRLLYCIKAD 894
++F++ + V G C F+ C + Q++ I F +K+ +++L C K
Sbjct: 838 AEMFHVQEMVVGQEKGNCSFQKNPTPCIIPQEQE--NIFHTIFAFFTKSGRKVLDCEKPG 895
Query: 895 PHCLNFLCNFGKMESGKEASVHIQLEGRPSILEMDETSALKFEIRATGFPEPNPRVIEL- 953
CL CNF + + ++ I + IL+ D +S ++F RA +P RV+E+
Sbjct: 896 ISCLTAHCNFSALAKEESRTIDIYMLLNTEILKKDSSSVIQFMSRAKVKVDPALRVVEIA 955
Query: 954 NKDENVAHVLLEGLHHQRPKRYFTIVIISSSLLLGLIVLLLISYVMWKAGFFKRQYKSIL 1013
+ + V+ E LH+ P+ Y II+ SLL+G+++ LL++ ++WK GFF+R+YK I+
Sbjct: 956 HGNPEEVTVVFEALHNLEPRGYVVGWIIAISLLVGILIFLLLAVLLWKMGFFRRRYKEII 1015
Query: 1014 QEENRR----DSWSYI 1025
+ E R DSW ++
Sbjct: 1016 EAEKNRKENEDSWDWV 1031
>gi|49170034 integrin, alpha 8 [Homo sapiens]
Length = 1063
Score = 312 bits (799), Expect = 1e-84
Identities = 278/1054 (26%), Positives = 470/1054 (44%), Gaps = 111/1054 (10%)
Query: 24 LCLGVPTGRPYNVDTESALLYQGPHNTLFGYSVVLHSHGANRW-LLVGAPTANWLANASV 82
+ L P + +N+D E +Y GP + FGY+V H A +LVGAP AN + +
Sbjct: 29 MLLWSPACQAFNLDVEKLTVYSGPKGSYFGYAVDFHIPDARTASVLVGAPKAN-TSQPDI 87
Query: 83 INPGAIYRCRIGKNPGQTCEQLQLGSPNGEPCG----KTCLEERDNQWLGVTLSRQPGEN 138
+ GA+Y C C Q+ + N K +E + NQW G T+
Sbjct: 88 VEGGAVYYCPWPAEGSAQCRQIPFDTTNNRKIRVNGTKEPIEFKSNQWFGATVK---AHK 144
Query: 139 GSIVTCG--HRWKNIFYIKNENKLPTGGCYGVPPDLRTELSKRIAPCYQDYVKKFGENFA 196
G +V C + W+ + K P G CY + +PC G+ +
Sbjct: 145 GKVVACAPLYHWRTLK--PTPEKDPVGTCYVAIQNFSAYAE--FSPCRNSNADPEGQGY- 199
Query: 197 SCQAGIS-SFYTKDLIVMGAPGSSYWTGSLFVYN----ITTNKYKAFL-----DKQNQVK 246
CQAG S FY +++G PGS YW G + + I +K L +KQ +V
Sbjct: 200 -CQAGFSLDFYKNGDLIVGGPGSFYWQGQVITASVADIIANYSFKDILRKLAGEKQTEVA 258
Query: 247 FGSY----LGYSVGAGHFRSQHTTEVVGGAPQHEQIGKAYIFSIDEKELNILHEMKGKKL 302
SY LGYSV AG F E+V G P+ Q Y+ I+ ++ + G+++
Sbjct: 259 PASYDDSYLGYSVAAGEFTGDSQQELVAGIPRGAQ-NFGYVSIINSTDMTFIQNFTGEQM 317
Query: 303 GSYFGASVCAVDLNADGFSDLLVGAPM------QSTIREEGRVFVYINSGSGAVMNAMET 356
SYFG +V D+N+DG D+LVGAP+ +S RE G++++Y+ S ++
Sbjct: 318 ASYFGYTVVVSDVNSDGLDDVLVGAPLFMEREFESNPREVGQIYLYLQVSS--LLFRDPQ 375
Query: 357 NLVGSDKYAARFGESIVNLGDIDNDGFEDVAIGAP-QEDDLQGAIYIYNGRADGISSTFS 415
L G++ + RFG ++ +LGD++ DG+ D+AIG P D +G + IYNG DG+++ S
Sbjct: 376 ILTGTETF-GRFGSAMAHLGDLNQDGYNDIAIGVPFAGKDQRGKVLIYNGNKDGLNTKPS 434
Query: 416 QRIEGLQISKSL-SMFGQSISGQIDADNNGYVDVAVGAFRSDSAVLLRTRPVVIVDAS-L 473
Q ++G+ S ++ S FG ++ G D D N Y D+ VGAF + + R RPVV VDA L
Sbjct: 435 QVLQGVWASHAVPSGFGFTLRGDSDIDKNDYPDLIVGAFGTGKVAVYRARPVVTVDAQLL 494
Query: 474 SHPESVNRTKFDC--VENGWPSVCIDLTLCFSYKGKEVPGYIVLFYNMSLDVNRKAESPP 531
HP +N C ++ + C L +C S G+ + IVL + LD ++ +
Sbjct: 495 LHPMIINLENKTCQVPDSMTSAACFSLRVCASVTGQSIANTIVLMAEVQLDSLKQKGAIK 554
Query: 532 RFYFSSNGTSDVITGSIQVSSREANCRTHQAFMRKDV--RDILTPIQIEAAYHLGPHVIS 589
R F N + + + + C+ ++R + RD L+PI I Y L
Sbjct: 555 RTLFLDNHQAHRVFPLVIKRQKSHQCQDFIVYLRDETEFRDKLSPINISLNYSL-----D 609
Query: 590 KRSTEEFPPLQPILQQKKEKDIMKKTINFARFCAHEN-CSADLQVSAKIGFLKPHENKTY 648
+ + +E ++PIL +E +I+ + + C +N C DL++SA+ +K
Sbjct: 610 ESTFKEGLEVKPILNYYRE-NIVSEQAHILVDCGEDNLCVPDLKLSAR-------PDKHQ 661
Query: 649 LAVGSMKTLMLNVSLFNAGDDAYETTLHVKLPVGLYFIKILELEE--KQINCEVTDNSGV 706
+ +G LML ++ N G+ AYE L V +P ++ I + + ++CE +
Sbjct: 662 VIIGDENHLMLIINARNEGEGAYEAELFVMIPEEADYVGIERNNKGFRPLSCEYKMENVT 721
Query: 707 VQLDCSIGYIYVDHLSRIDISFLLDVSSLSRAEEDLSITVHATCENEEEMDNLKHSRVTV 766
+ C +G V + + V L + ++ + N+ DN + V++
Sbjct: 722 RMVVCDLGNPMVSG-TNYSLGLRFAVPRLEKTNMSINFDLQIRSSNK---DNPDSNFVSL 777
Query: 767 AIPLKYEVKLTVHGFVNPTSFVYG-SNDENEPETCMVEKMN-LTFHVI---NTGNSMAPN 821
I + ++ + G +P V N E E E E++ L H+ N G S +
Sbjct: 778 QINITAVAQVEIRGVSHPPQIVLPIHNWEPEEEPHKEEEVGPLVEHIYELHNIGPSTISD 837
Query: 822 VSVEIMVPNSFSPQTDKLFNILDVQT-------TTGECHFENYQRVCALEQQKSAMQTLK 874
+E+ P FS + + L I +QT + ++ + + E L+
Sbjct: 838 TILEVGWP--FSARDEFLLYIFHIQTLGPLQCQPNPNINPQDIKPAASPEDTPELSAFLR 895
Query: 875 G-------------IVRFLSKTDKRLLYCIKADPHCLNFLCNFGKMESGKEA--SVHIQL 919
+V F ++ ++L C + CL C G++E G+ A V +L
Sbjct: 896 NSTIPHLVRKRDVHVVEFHRQSPAKILNCTNIE--CLQISCAVGRLEGGESAVLKVRSRL 953
Query: 920 EGRPSILEMDETSAL----KFEIRATGFPEPNPRVIELNKDENVAHVLLEGLHHQRPKRY 975
+ ++ AL FE++ + + ++ E + + + P
Sbjct: 954 WAHTFLQRKNDPYALASLVSFEVKKMPYTDQPAKLPE------GSIAIKTSVIWATPNVS 1007
Query: 976 FTIV--IISSSLLLGLIVLLLISYVMWKAGFFKR 1007
F+I +I ++LLGL+VL +++ +WK GFF R
Sbjct: 1008 FSIPLWVIILAILLGLLVLAILTLALWKCGFFDR 1041
>gi|4504763 integrin alpha-V isoform 1 precursor [Homo sapiens]
Length = 1048
Score = 296 bits (757), Expect = 9e-80
Identities = 294/1096 (26%), Positives = 485/1096 (44%), Gaps = 113/1096 (10%)
Query: 1 MAWEARREPGPRRAAVRETVMLLLCLGVPTGRPYNVDTESALLYQGPHNTLFGYSV--VL 58
MA+ RR R R +LL L +P R +N+D +S Y GP + FG++V +
Sbjct: 1 MAFPPRRR---LRLGPRGLPLLLSGLLLPLCRAFNLDVDSPAEYSGPEGSYFGFAVDFFV 57
Query: 59 HSHGANRWLLVGAPTANWLANASVINPGAIYRCRIGKNPGQTCEQLQLGSPNGEPCGKTC 118
S + +LLVGAP AN ++ G + +C + C+ ++ + K
Sbjct: 58 PSASSRMFLLVGAPKAN-TTQPGIVEGGQVLKCDWSST--RRCQPIEFDATGNRDYAKDD 114
Query: 119 -LEERDNQWLGVTLSRQPGENGSIVTCG--HRWKNIFYIKNENKLPTGGCYGVPPDLRTE 175
LE + +QW G ++ + I+ C + W+ +K E + P G C+ E
Sbjct: 115 PLEFKSHQWFGASVR---SKQDKILACAPLYHWRT--EMKQERE-PVGTCFLQDGTKTVE 168
Query: 176 LSKRIAPCYQDYVKKFGENFASCQAGISSFYTK-DLIVMGAPGSSYWTGSLF-------- 226
APC + G+ F CQ G S +TK D +++G PGS YW G L
Sbjct: 169 Y----APCRSQDIDADGQGF--CQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIV 222
Query: 227 ------VYNITTNKYKAFLDKQNQVKFGSYLGYSVGAGHFRSQHTTEVVGGAPQHEQ-IG 279
VY+I N A Q + SYLGYSV G F + V G P+ + +G
Sbjct: 223 SKYDPNVYSIKYNNQLATRTAQ-AIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLG 281
Query: 280 KAYIFSIDEKELNILHEMKGKKLGSYFGASVCAVDLNADGFSDLLVGAPM------QSTI 333
YI+ D K ++ L+ G+++ +YFG SV A D+N D ++D+ +GAP+ +
Sbjct: 282 MVYIY--DGKNMSSLYNFTGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKL 339
Query: 334 REEGRVFVYINSGSGAVMNAMETNLVGSDKYAARFGESIVNLGDIDNDGFEDVAIGAPQE 393
+E G+V V + SG + T L G + +A RFG +I LGD+D DGF D+AI AP
Sbjct: 340 QEVGQVSVSLQRASG---DFQTTKLNGFEVFA-RFGSAIAPLGDLDQDGFNDIAIAAPYG 395
Query: 394 -DDLQGAIYIYNGRADGISSTFSQRIEGLQISKSLS-MFGQSISGQIDADNNGYVDVAVG 451
+D +G +YI+NGR+ G+++ SQ +EG ++S+ FG S+ G D D NGY D+ VG
Sbjct: 396 GEDKKGIVYIFNGRSTGLNAVPSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVG 455
Query: 452 AFRSDSAVLLRTRPVVIVDASLS-HPESVNRTKFDCVENG--WPSVCIDLTLCFSYKGKE 508
AF D A+L R RPV+ V+A L +P +N+ C G C ++ C GK
Sbjct: 456 AFGVDRAILYRARPVITVNAGLEVYPSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKG 515
Query: 509 V-PGYIVLFYNMSLDVNRKAESPPRFYFSSNGTSDVITGSIQVSSREANCRTHQAFMR-- 565
V P + + LD ++ + R F + + C A++R
Sbjct: 516 VLPRKLNFQVELLLDKLKQKGAIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDE 575
Query: 566 KDVRDILTPIQIEAAYHLGPHVISKRSTEEFPPLQPILQQKKEKDIMKKTINFARFCAHE 625
+ RD LTPI I Y L R+ + LQPIL Q +I ++ + C +
Sbjct: 576 SEFRDKLTPITIFMEYRL-----DYRTAADTTGLQPILNQFTPANISRQA-HILLDCGED 629
Query: 626 N-CSADLQVSAKIGFLKPHENKTYLAVGSMKTLMLNVSLFNAGDDAYETTLHVKLPVGLY 684
N C L+VS + + K Y +G L L V N G+ AYE L V +P+
Sbjct: 630 NVCKPKLEVS-----VDSDQKKIY--IGDDNPLTLIVKAQNQGEGAYEAELIVSIPLQAD 682
Query: 685 FIKILELEE--KQINCEVTDNSGVVQLDCSIGYIYVDHLSRIDISFLLDVSSLSRAEEDL 742
FI ++ E +++C + Q+ C +G + + L S ++E D
Sbjct: 683 FIGVVRNNEALARLSCAFKTENQTRQVVCDLGN---PMKAGTQLLAGLRFSVHQQSEMDT 739
Query: 743 SITVHATCENEEEMDNLK---HSRVTVAIPLKYEVK---LTVHGFVNPTSFVYGSNDENE 796
S+ ++ D + +V +A+ E++ H F+ ++ + N E E
Sbjct: 740 SVKFDLQIQSSNLFDKVSPVVSHKVDLAVLAAVEIRGVSSPDHIFLPIPNWEHKENPETE 799
Query: 797 PETCMVEKMNLTFHVINTGNSMAPNVSVEIMVPNSFSPQTDKLFNILDVQTTTGECHFEN 856
+ V + + + N G S + + P ++ T L IL G + +
Sbjct: 800 EDVGPV--VQHIYELRNNGPSSFSKAMLHLQWPYKYNNNT--LLYILHYD-IDGPMNCTS 854
Query: 857 YQRVCALEQQKSAMQTLK--GIVRFLSKTD----KRLLYCIKADPH--------CLNFLC 902
+ L + S++QT + V + D KR L + D H CL +C
Sbjct: 855 DMEINPLRIKISSLQTTEKNDTVAGQGERDHLITKRDLALSEGDIHTLGCGVAQCLKIVC 914
Query: 903 NFGKMESGKEASVHIQLEGRPSILEMDETSALKFEIRATG------FPEPNPRVIELNKD 956
G+++ GK A ++++ E + ++++ FP N + ++
Sbjct: 915 QVGRLDRGKSAILYVKSLLWTETFMNKENQNHSYSLKSSASFNVIEFPYKNLPIEDITNS 974
Query: 957 ENVAHVLLEGLHHQRPKRYFTIVIISSSLLLGLIVLLLISYVMWKAGFFKRQYKSILQEE 1016
V + G+ Q + +I ++L GL++L ++ +VM++ GFFKR + +E+
Sbjct: 975 TLVTTNVTWGI--QPAPMPVPVWVIILAVLAGLLLLAVLVFVMYRMGFFKR-VRPPQEEQ 1031
Query: 1017 NRRDSWSYINSKSNDD 1032
R + N + N +
Sbjct: 1032 EREQLQPHENGEGNSE 1047
>gi|56237029 integrin alpha 5 precursor [Homo sapiens]
Length = 1049
Score = 292 bits (748), Expect = 1e-78
Identities = 291/1072 (27%), Positives = 467/1072 (43%), Gaps = 135/1072 (12%)
Query: 10 GPRRAAVRETVMLLLCLGVPTGRPYNVDTESALLYQGPHNTLFGYSVVLHSHGANRW-LL 68
GPRR ++LLL P +N+D E+ + GP + FG+SV + G + +L
Sbjct: 18 GPRRRPPLLPLLLLLLPPPPRVGGFNLDAEAPAVLSGPPGSFFGFSVEFYRPGTDGVSVL 77
Query: 69 VGAPTANWLANASVINPGAIYRCRIGKNPGQTCEQLQLGSPNGEPC--------GKTCLE 120
VGAP AN + V+ GA+Y C G +P Q C ++ S G+ +E
Sbjct: 78 VGAPKAN-TSQPGVLQGGAVYLCPWGASPTQ-CTPIEFDSKGSRLLESSLSSSEGEEPVE 135
Query: 121 ERDNQWLGVTLSRQPGENGSIVTCG--HRWKNIFYIKNENKLPTGGCYGVPPDLRTELSK 178
+ QW G T+ SI+ C + W+ K P G CY L T+
Sbjct: 136 YKSLQWFGATVR---AHGSSILACAPLYSWRTE---KEPLSDPVGTCY-----LSTDNFT 184
Query: 179 RI---APCYQDYVKKFGENFASCQAGISSFYTKD-LIVMGAPGSSYWTGSLFVYN---IT 231
RI APC D+ G+ + CQ G S+ +TK +V+G PGS +W G + I
Sbjct: 185 RILEYAPCRSDFSWAAGQGY--CQGGFSAEFTKTGRVVLGGPGSYFWQGQILSATQEQIA 242
Query: 232 TNKYKAFL----------DKQNQVKFGSYLGYSVGAGHFRSQHTTEVVGGAPQHEQIGKA 281
+ Y +L + + + SYLGYSV G F T + V G P+ +
Sbjct: 243 ESYYPEYLINLVQGQLQTRQASSIYDDSYLGYSVAVGEFSGDDTEDFVAGVPKGN-LTYG 301
Query: 282 YIFSIDEKELNILHEMKGKKLGSYFGASVCAVDLNADGFSDLLVGAPM------QSTIRE 335
Y+ ++ ++ L+ G+++ SYFG +V A D+N DG DLLVGAP+ +E
Sbjct: 302 YVTILNGSDIRSLYNFSGEQMASYFGYAVAATDVNGDGLDDLLVGAPLLMDRTPDGRPQE 361
Query: 336 EGRVFVYINSGSGAVMNAMETNLVGSDKYAARFGESIVNLGDIDNDGFEDVAIGAP-QED 394
GRV+VY+ +G + L G D++ RFG S+ LGD+D DG+ DVAIGAP +
Sbjct: 362 VGRVYVYLQHPAG-IEPTPTLTLTGHDEF-GRFGSSLTPLGDLDQDGYNDVAIGAPFGGE 419
Query: 395 DLQGAIYIYNGRADGISSTFSQRIEGL-QISKSLSMFGQSISGQIDADNNGYVDVAVGAF 453
QG ++++ G G+ S SQ ++ L S + FG ++ G D D NGY D+ VG+F
Sbjct: 420 TQQGVVFVFPGGPGGLGSKPSQVLQPLWAASHTPDFFGSALRGGRDLDGNGYPDLIVGSF 479
Query: 454 RSDSAVLLRTRPVVIVDASLS-HPESVNRTKFDCVENGWPSVCIDLTLCFSYKGKEVPGY 512
D AV+ R RP+V ASL+ P N + C G P CI+L+ C + GK V
Sbjct: 480 GVDKAVVYRGRPIVSASASLTIFPAMFNPEERSCSLEGNPVACINLSFCLNASGKHVADS 539
Query: 513 IVLFYNMSLDVNRKAESPPR-FYFSSNGTSDVITGSIQVSSREANCRTHQAFMR--KDVR 569
I + LD ++ R + +S + T IQ +RE +CR + ++R + R
Sbjct: 540 IGFTVELQLDWQKQKGGVRRALFLASRQATLTQTLLIQNGARE-DCREMKIYLRNESEFR 598
Query: 570 DILTPIQIEAAYHLGPHVISKRSTEEFPPLQPILQQKKEKDIMKKTINFARFCAHEN-CS 628
D L+PI I + L P ++ + L+P L + + I K C +N C
Sbjct: 599 DKLSPIHIALNFSLDP-----QAPVDSHGLRPALHYQSKSRIEDKA-QILLDCGEDNICV 652
Query: 629 ADLQVSAKIGFLKPHENKTYLAVGSMKTLMLNVSLFNAGD-DAYETTLHVKLPVGLYFIK 687
DLQ+ + +N YL G L L N G+ AYE L V P +
Sbjct: 653 PDLQLE-----VFGEQNHVYL--GDKNALNLTFHAQNVGEGGAYEAELRVTAPPEAEYSG 705
Query: 688 ILEL--EEKQINCEVTDNSGVVQLDCSIGYIYVDHLS-----RIDISFLLDVSSLSRAEE 740
++ ++C+ + L C +G S R + L D + +
Sbjct: 706 LVRHPGNFSSLSCDYFAVNQSRLLVCDLGNPMKAGASLWGGLRFTVPHLRDTKKTIQFDF 765
Query: 741 DLSITVHATCENEEEMDNLKHSRVTVAIPLKYEVKLTVHGFVNPTSFVY-----GSNDEN 795
+ + ++N + V+ + ++ + ++T++G P + ++ D+
Sbjct: 766 QIL---------SKNLNNSQSDVVSFRLSVEAQAQVTLNGVSKPEAVLFPVSDWHPRDQP 816
Query: 796 EPETCMVEKMNLTFHVINTGNSMAPNVSVEIMVPNSFSPQTDKLFNILDVQTTTG-ECHF 854
+ E + ++ + +IN G S +E+ P + Q +L V TG C
Sbjct: 817 QKEEDLGPAVHHVYELINQGPSSISQGVLELSCPQALEGQ-----QLLYVTRVTGLNCTT 871
Query: 855 ENYQRVCALEQQKSA----MQTLKGIVRFLSKTDKRLLYCIKADPHCLNFLCNFGKMESG 910
+ LE Q + R + + ++L C +A+ C C G +
Sbjct: 872 NHPINPKGLELDPEGSLHHQQKREAPSRSSASSGPQILKCPEAE--CFRLRCELGPLHQQ 929
Query: 911 KEASVH----------IQLEGRPSILEMDET-SALKFEIRATGFPEPNPRVIELNKDENV 959
+ S+ +Q E +P L+ + ALK R P P+ K+ V
Sbjct: 930 ESQSLQLHFRVWAKTFLQREHQPFSLQCEAVYKALKMPYRI--LPRQLPQ-----KERQV 982
Query: 960 AHVL----LEGLHHQRPKRYFTIVIISSSLLLGLIVLLLISYVMWKAGFFKR 1007
A + EG + + II ++L GL++L L+ Y+++K GFFKR
Sbjct: 983 ATAVQWTKAEGSYG------VPLWIIILAILFGLLLLGLLIYILYKLGFFKR 1028
>gi|119395742 integrin alpha chain, alpha 6 isoform b precursor [Homo
sapiens]
Length = 1073
Score = 286 bits (731), Expect = 9e-77
Identities = 282/1086 (25%), Positives = 473/1086 (43%), Gaps = 129/1086 (11%)
Query: 14 AAVRETVMLLLCLGVPT--GRPYNVDT--ESALLYQGPHNTLFGYSVVLH---SHGANRW 66
AA + +L L G+ + G +N+DT ++ + G +LFG+S+ +H R
Sbjct: 2 AAAGQLCLLYLSAGLLSRLGAAFNLDTREDNVIRKYGDPGSLFGFSLAMHWQLQPEDKRL 61
Query: 67 LLVGAPTANWLANASVINPGAIYRCRI-GKNPGQTCEQLQLGSPNGEPCGKTCLEERDNQ 125
LLVGAP A L G +Y C I + P C +++ + + +P E +++Q
Sbjct: 62 LLVGAPRAEALPLQRANRTGGLYSCDITARGP---CTRIEFDN-DADPTS----ESKEDQ 113
Query: 126 WLGVTLSRQPGENGSIVTCGHRWKNIFYI--KNENKLPTGGCYGVPPDLRTELSKRIAP- 182
W+GVT+ Q G G +VTC HR++ ++ K E++ G CY + +LR E
Sbjct: 114 WMGVTVQSQ-GPGGKVVTCAHRYEKRQHVNTKQESRDIFGRCYVLSQNLRIEDDMDGGDW 172
Query: 183 CYQDYVKKFGENFASCQAGISSFYTKDL--IVMGAPGSSYWTGSLFVYNITTNKYKAFLD 240
+ D + E F SCQ G+++ +TKD IV GAPG+ W G + V + +
Sbjct: 173 SFCDGRLRGHEKFGSCQQGVAATFTKDFHYIVFGAPGTYNWKGIVRVEQKNNTFFDMNIF 232
Query: 241 KQNQVKFG---------------SYLGYSVGAGH-FRSQHTTEVVGGAPQHEQIGKAYIF 284
+ + G SYLG+S+ +G S+ V GAP+ G +
Sbjct: 233 EDGPYEVGGETEHDESLVPVPANSYLGFSLDSGKGIVSKDEITFVSGAPRANHSGAVVLL 292
Query: 285 SIDEKELNIL--HEMKGKKLGSYFGASVCAVDLNADGFSDLLVGAPMQSTIREE--GRVF 340
D K ++L H G+ L S FG V VDLN DG+ D+++GAP E G V+
Sbjct: 293 KRDMKSAHLLPEHIFDGEGLASSFGYDVAVVDLNKDGWQDIVIGAPQYFDRDGEVGGAVY 352
Query: 341 VYINSGSGAVMNAMETNLVGSDKYAARFGESIVNLGDIDNDGFEDVAIGAPQEDDLQGAI 400
VY+N G N L G+ + FG ++ N+GDI+ DG+ D+A+GAP +D G +
Sbjct: 353 VYMNQ-QGRWNNVKPIRLNGTKD--SMFGIAVKNIGDINQDGYPDIAVGAPYDD--LGKV 407
Query: 401 YIYNGRADGISSTFSQRIEGLQISKSLSMFGQSISGQIDADNNGYVDVAVGAFRSDSAVL 460
+IY+G A+GI++ +Q ++G+ FG SI+G +D D N Y DVAVG+ SDS +
Sbjct: 408 FIYHGSANGINTKPTQVLKGIS-----PYFGYSIAGNMDLDRNSYPDVAVGSL-SDSVTI 461
Query: 461 LRTRPVVIVDASLS-HPESVN-RTKFDCVENGWPS-VCIDLTLCFSYKGKEVPGYIVLFY 517
R+RPV+ + +++ P ++ R K C G PS +C+ + CF Y Y
Sbjct: 462 FRSRPVINIQKTITVTPNRIDLRQKTAC---GAPSGICLQVKSCFEYTANPAG------Y 512
Query: 518 NMSLDV---------NRKAESPPRFYFSSNGTSDVITGSIQVS-SREANCRTHQAFMRKD 567
N S+ + RK+ R F + G+ T + + ++ C +++ +
Sbjct: 513 NPSISIVGTLEAEKERRKSGLSSRVQFRNQGSEPKYTQELTLKRQKQKVCMEETLWLQDN 572
Query: 568 VRDILTPIQIEAAYHLGPHVISKRSTEEFPPLQPILQQKKEKDIMKKTINFARFCAHEN- 626
+RD L PI I A+ + S+R P + PIL + K C +N
Sbjct: 573 IRDKLRPIPITASVEI-QEPSSRRRVNSLPEVLPILNSDEPKTAHIDVHFLKEGCGDDNV 631
Query: 627 CSADLQV----------SAKIGFLKPHENKTYLAVGSMKTLMLNVSLFNA---------- 666
C+++L++ K +L + L + K + L +++ N+
Sbjct: 632 CNSNLKLEYKFCTREGNQDKFSYLPIQKGVPELVLKDQKDIALEITVTNSPSNPRNPTKD 691
Query: 667 GDDAYETTLHVKLPVGLYFIKILELE---EKQINCEVTDNSGVVQLDCSIGYIYVDHLSR 723
GDDA+E L P L + EL EKQ++C N Q DC +G +
Sbjct: 692 GDDAHEAKLIATFPDTLTYSAYRELRAFPEKQLSCVANQNGS--QADCELGNPF---KRN 746
Query: 724 IDISFLLDVSSLSRAEEDLSITVHATCENEEEMDNLKHSRVTVAIPLKYEVKLTVHGFVN 783
+++F L +S+ + + ++ E DNL + +T + E+ L+V G
Sbjct: 747 SNVTFYLVLSTTEVTFDTPDLDINLKLETTSNQDNL--APITAKAKVVIELLLSVSGVAK 804
Query: 784 PTSFVYGSNDENE----PETCMVEKMNLTFHVINTGNSMA--PNVSVEIMVPNSFSPQTD 837
P+ +G E E + + F VIN G + ++ I P S
Sbjct: 805 PSQVYFGGTVVGEQAMKSEDEVGSLIEYEFRVINLGKPLTNLGTATLNIQWPKEISNGKW 864
Query: 838 KLFNILDVQTTTGECHFENYQRVCALEQQKSAMQTLKGIVRFLSKTDKR----------- 886
L+ + + E + + +L +S K + D R
Sbjct: 865 LLYLVKVESKGLEKVTCEPQKEINSLNLTESHNSRKKREITEKQIDDNRKFSLFAERKYQ 924
Query: 887 LLYCIKADPHCLNFLCNFGKMESGKEASVHIQLEGRPSILEMDETSALKFEIRATGFPEP 946
L C + +C+N C ++S + +L + E + + L +RA F +
Sbjct: 925 TLNC-SVNVNCVNIRCPLRGLDSKASLILRSRLWNSTFLEEYSKLNYLDILMRA--FIDV 981
Query: 947 NPRVIELNKDENVAHVLLEGLHHQRPKRYFTIV--IISSSLLLGLIVLLLISYVMWKAGF 1004
+ V + + +Y + II ++L G+++L L+ +++WK GF
Sbjct: 982 TAAAENIRLPNAGTQVRVTVFPSKTVAQYSGVPWWIILVAILAGILMLALLVFILWKCGF 1041
Query: 1005 FKRQYK 1010
FKR K
Sbjct: 1042 FKRNKK 1047
>gi|119395740 integrin alpha chain, alpha 6 isoform a precursor [Homo
sapiens]
Length = 1091
Score = 285 bits (728), Expect = 2e-76
Identities = 281/1083 (25%), Positives = 472/1083 (43%), Gaps = 129/1083 (11%)
Query: 14 AAVRETVMLLLCLGVPT--GRPYNVDT--ESALLYQGPHNTLFGYSVVLH---SHGANRW 66
AA + +L L G+ + G +N+DT ++ + G +LFG+S+ +H R
Sbjct: 2 AAAGQLCLLYLSAGLLSRLGAAFNLDTREDNVIRKYGDPGSLFGFSLAMHWQLQPEDKRL 61
Query: 67 LLVGAPTANWLANASVINPGAIYRCRI-GKNPGQTCEQLQLGSPNGEPCGKTCLEERDNQ 125
LLVGAP A L G +Y C I + P C +++ + + +P E +++Q
Sbjct: 62 LLVGAPRAEALPLQRANRTGGLYSCDITARGP---CTRIEFDN-DADPTS----ESKEDQ 113
Query: 126 WLGVTLSRQPGENGSIVTCGHRWKNIFYI--KNENKLPTGGCYGVPPDLRTELSKRIAP- 182
W+GVT+ Q G G +VTC HR++ ++ K E++ G CY + +LR E
Sbjct: 114 WMGVTVQSQ-GPGGKVVTCAHRYEKRQHVNTKQESRDIFGRCYVLSQNLRIEDDMDGGDW 172
Query: 183 CYQDYVKKFGENFASCQAGISSFYTKDL--IVMGAPGSSYWTGSLFVYNITTNKYKAFLD 240
+ D + E F SCQ G+++ +TKD IV GAPG+ W G + V + +
Sbjct: 173 SFCDGRLRGHEKFGSCQQGVAATFTKDFHYIVFGAPGTYNWKGIVRVEQKNNTFFDMNIF 232
Query: 241 KQNQVKFG---------------SYLGYSVGAGH-FRSQHTTEVVGGAPQHEQIGKAYIF 284
+ + G SYLG+S+ +G S+ V GAP+ G +
Sbjct: 233 EDGPYEVGGETEHDESLVPVPANSYLGFSLDSGKGIVSKDEITFVSGAPRANHSGAVVLL 292
Query: 285 SIDEKELNIL--HEMKGKKLGSYFGASVCAVDLNADGFSDLLVGAPMQSTIREE--GRVF 340
D K ++L H G+ L S FG V VDLN DG+ D+++GAP E G V+
Sbjct: 293 KRDMKSAHLLPEHIFDGEGLASSFGYDVAVVDLNKDGWQDIVIGAPQYFDRDGEVGGAVY 352
Query: 341 VYINSGSGAVMNAMETNLVGSDKYAARFGESIVNLGDIDNDGFEDVAIGAPQEDDLQGAI 400
VY+N G N L G+ + FG ++ N+GDI+ DG+ D+A+GAP +D G +
Sbjct: 353 VYMNQ-QGRWNNVKPIRLNGTKD--SMFGIAVKNIGDINQDGYPDIAVGAPYDD--LGKV 407
Query: 401 YIYNGRADGISSTFSQRIEGLQISKSLSMFGQSISGQIDADNNGYVDVAVGAFRSDSAVL 460
+IY+G A+GI++ +Q ++G+ FG SI+G +D D N Y DVAVG+ SDS +
Sbjct: 408 FIYHGSANGINTKPTQVLKGIS-----PYFGYSIAGNMDLDRNSYPDVAVGSL-SDSVTI 461
Query: 461 LRTRPVVIVDASLS-HPESVN-RTKFDCVENGWPS-VCIDLTLCFSYKGKEVPGYIVLFY 517
R+RPV+ + +++ P ++ R K C G PS +C+ + CF Y Y
Sbjct: 462 FRSRPVINIQKTITVTPNRIDLRQKTAC---GAPSGICLQVKSCFEYTANPAG------Y 512
Query: 518 NMSLDV---------NRKAESPPRFYFSSNGTSDVITGSIQVS-SREANCRTHQAFMRKD 567
N S+ + RK+ R F + G+ T + + ++ C +++ +
Sbjct: 513 NPSISIVGTLEAEKERRKSGLSSRVQFRNQGSEPKYTQELTLKRQKQKVCMEETLWLQDN 572
Query: 568 VRDILTPIQIEAAYHLGPHVISKRSTEEFPPLQPILQQKKEKDIMKKTINFARFCAHEN- 626
+RD L PI I A+ + S+R P + PIL + K C +N
Sbjct: 573 IRDKLRPIPITASVEI-QEPSSRRRVNSLPEVLPILNSDEPKTAHIDVHFLKEGCGDDNV 631
Query: 627 CSADLQV----------SAKIGFLKPHENKTYLAVGSMKTLMLNVSLFNA---------- 666
C+++L++ K +L + L + K + L +++ N+
Sbjct: 632 CNSNLKLEYKFCTREGNQDKFSYLPIQKGVPELVLKDQKDIALEITVTNSPSNPRNPTKD 691
Query: 667 GDDAYETTLHVKLPVGLYFIKILELE---EKQINCEVTDNSGVVQLDCSIGYIYVDHLSR 723
GDDA+E L P L + EL EKQ++C N Q DC +G +
Sbjct: 692 GDDAHEAKLIATFPDTLTYSAYRELRAFPEKQLSCVANQNGS--QADCELGNPF---KRN 746
Query: 724 IDISFLLDVSSLSRAEEDLSITVHATCENEEEMDNLKHSRVTVAIPLKYEVKLTVHGFVN 783
+++F L +S+ + + ++ E DNL + +T + E+ L+V G
Sbjct: 747 SNVTFYLVLSTTEVTFDTPDLDINLKLETTSNQDNL--APITAKAKVVIELLLSVSGVAK 804
Query: 784 PTSFVYGSNDENE----PETCMVEKMNLTFHVINTGNSMA--PNVSVEIMVPNSFSPQTD 837
P+ +G E E + + F VIN G + ++ I P S
Sbjct: 805 PSQVYFGGTVVGEQAMKSEDEVGSLIEYEFRVINLGKPLTNLGTATLNIQWPKEISNGKW 864
Query: 838 KLFNILDVQTTTGECHFENYQRVCALEQQKSAMQTLKGIVRFLSKTDKR----------- 886
L+ + + E + + +L +S K + D R
Sbjct: 865 LLYLVKVESKGLEKVTCEPQKEINSLNLTESHNSRKKREITEKQIDDNRKFSLFAERKYQ 924
Query: 887 LLYCIKADPHCLNFLCNFGKMESGKEASVHIQLEGRPSILEMDETSALKFEIRATGFPEP 946
L C + +C+N C ++S + +L + E + + L +RA F +
Sbjct: 925 TLNC-SVNVNCVNIRCPLRGLDSKASLILRSRLWNSTFLEEYSKLNYLDILMRA--FIDV 981
Query: 947 NPRVIELNKDENVAHVLLEGLHHQRPKRYFTIV--IISSSLLLGLIVLLLISYVMWKAGF 1004
+ V + + +Y + II ++L G+++L L+ +++WK GF
Sbjct: 982 TAAAENIRLPNAGTQVRVTVFPSKTVAQYSGVPWWIILVAILAGILMLALLVFILWKCGF 1041
Query: 1005 FKR 1007
FKR
Sbjct: 1042 FKR 1044
>gi|223468595 integrin alpha-V isoform 2 [Homo sapiens]
Length = 1002
Score = 272 bits (696), Expect = 1e-72
Identities = 273/1029 (26%), Positives = 453/1029 (44%), Gaps = 108/1029 (10%)
Query: 66 WLLVGAPTANWLANASVINPGAIYRCRIGKNPGQTCEQLQLGSPNGEPCGKTC-LEERDN 124
+LLVGAP AN ++ G + +C + C+ ++ + K LE + +
Sbjct: 19 FLLVGAPKAN-TTQPGIVEGGQVLKCDWSST--RRCQPIEFDATGNRDYAKDDPLEFKSH 75
Query: 125 QWLGVTLSRQPGENGSIVTCG--HRWKNIFYIKNENKLPTGGCYGVPPDLRTELSKRIAP 182
QW G ++ + I+ C + W+ +K E + P G C+ E AP
Sbjct: 76 QWFGASVR---SKQDKILACAPLYHWRT--EMKQERE-PVGTCFLQDGTKTVEY----AP 125
Query: 183 CYQDYVKKFGENFASCQAGISSFYTK-DLIVMGAPGSSYWTGSLF--------------V 227
C + G+ F CQ G S +TK D +++G PGS YW G L V
Sbjct: 126 CRSQDIDADGQGF--CQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPNV 183
Query: 228 YNITTNKYKAFLDKQNQVKFGSYLGYSVGAGHFRSQHTTEVVGGAPQHEQ-IGKAYIFSI 286
Y+I N A Q + SYLGYSV G F + V G P+ + +G YI+
Sbjct: 184 YSIKYNNQLATRTAQ-AIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIY-- 240
Query: 287 DEKELNILHEMKGKKLGSYFGASVCAVDLNADGFSDLLVGAPM------QSTIREEGRVF 340
D K ++ L+ G+++ +YFG SV A D+N D ++D+ +GAP+ ++E G+V
Sbjct: 241 DGKNMSSLYNFTGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVS 300
Query: 341 VYINSGSGAVMNAMETNLVGSDKYAARFGESIVNLGDIDNDGFEDVAIGAPQE-DDLQGA 399
V + SG + T L G + +A RFG +I LGD+D DGF D+AI AP +D +G
Sbjct: 301 VSLQRASG---DFQTTKLNGFEVFA-RFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGI 356
Query: 400 IYIYNGRADGISSTFSQRIEGLQISKSLS-MFGQSISGQIDADNNGYVDVAVGAFRSDSA 458
+YI+NGR+ G+++ SQ +EG ++S+ FG S+ G D D NGY D+ VGAF D A
Sbjct: 357 VYIFNGRSTGLNAVPSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRA 416
Query: 459 VLLRTRPVVIVDASLS-HPESVNRTKFDCVENG--WPSVCIDLTLCFSYKGKEV-PGYIV 514
+L R RPV+ V+A L +P +N+ C G C ++ C GK V P +
Sbjct: 417 ILYRARPVITVNAGLEVYPSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLN 476
Query: 515 LFYNMSLDVNRKAESPPRFYFSSNGTSDVITGSIQVSSREANCRTHQAFMR--KDVRDIL 572
+ LD ++ + R F + + C A++R + RD L
Sbjct: 477 FQVELLLDKLKQKGAIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKL 536
Query: 573 TPIQIEAAYHLGPHVISKRSTEEFPPLQPILQQKKEKDIMKKTINFARFCAHEN-CSADL 631
TPI I Y L R+ + LQPIL Q +I ++ + C +N C L
Sbjct: 537 TPITIFMEYRL-----DYRTAADTTGLQPILNQFTPANISRQA-HILLDCGEDNVCKPKL 590
Query: 632 QVSAKIGFLKPHENKTYLAVGSMKTLMLNVSLFNAGDDAYETTLHVKLPVGLYFIKILEL 691
+VS + + K Y +G L L V N G+ AYE L V +P+ FI ++
Sbjct: 591 EVS-----VDSDQKKIY--IGDDNPLTLIVKAQNQGEGAYEAELIVSIPLQADFIGVVRN 643
Query: 692 EE--KQINCEVTDNSGVVQLDCSIGYIYVDHLSRIDISFLLDVSSLSRAEEDLSITVHAT 749
E +++C + Q+ C +G + + L S ++E D S+
Sbjct: 644 NEALARLSCAFKTENQTRQVVCDLGN---PMKAGTQLLAGLRFSVHQQSEMDTSVKFDLQ 700
Query: 750 CENEEEMDNLK---HSRVTVAIPLKYEVK---LTVHGFVNPTSFVYGSNDENEPETCMVE 803
++ D + +V +A+ E++ H F+ ++ + N E E + V
Sbjct: 701 IQSSNLFDKVSPVVSHKVDLAVLAAVEIRGVSSPDHIFLPIPNWEHKENPETEEDVGPV- 759
Query: 804 KMNLTFHVINTGNSMAPNVSVEIMVPNSFSPQTDKLFNILDVQTTTGECHFENYQRVCAL 863
+ + + N G S + + P ++ T L IL G + + + L
Sbjct: 760 -VQHIYELRNNGPSSFSKAMLHLQWPYKYNNNT--LLYILHYD-IDGPMNCTSDMEINPL 815
Query: 864 EQQKSAMQTLK--GIVRFLSKTD----KRLLYCIKADPH--------CLNFLCNFGKMES 909
+ S++QT + V + D KR L + D H CL +C G+++
Sbjct: 816 RIKISSLQTTEKNDTVAGQGERDHLITKRDLALSEGDIHTLGCGVAQCLKIVCQVGRLDR 875
Query: 910 GKEASVHIQLEGRPSILEMDETSALKFEIRATG------FPEPNPRVIELNKDENVAHVL 963
GK A ++++ E + ++++ FP N + ++ V +
Sbjct: 876 GKSAILYVKSLLWTETFMNKENQNHSYSLKSSASFNVIEFPYKNLPIEDITNSTLVTTNV 935
Query: 964 LEGLHHQRPKRYFTIVIISSSLLLGLIVLLLISYVMWKAGFFKRQYKSILQEENRRDSWS 1023
G+ Q + +I ++L GL++L ++ +VM++ GFFKR + +E+ R
Sbjct: 936 TWGI--QPAPMPVPVWVIILAVLAGLLLLAVLVFVMYRMGFFKR-VRPPQEEQEREQLQP 992
Query: 1024 YINSKSNDD 1032
+ N + N +
Sbjct: 993 HENGEGNSE 1001
>gi|223468597 integrin alpha-V isoform 3 precursor [Homo sapiens]
Length = 1012
Score = 263 bits (671), Expect = 8e-70
Identities = 280/1082 (25%), Positives = 472/1082 (43%), Gaps = 121/1082 (11%)
Query: 1 MAWEARREPGPRRAAVRETVMLLLCLGVPTGRPYNVDTESALLYQGPHNTLFGYSV--VL 58
MA+ RR R R +LL L +P R +N+D +S Y GP + FG++V +
Sbjct: 1 MAFPPRRR---LRLGPRGLPLLLSGLLLPLCRAFNLDVDSPAEYSGPEGSYFGFAVDFFV 57
Query: 59 HSHGANRWLLVGAPTANWLANASVINPGAIYRCRIGKNPGQTCEQLQLGSPNGEPCGKTC 118
S + +LLVGAP AN ++ G + +C + C+ ++ + K
Sbjct: 58 PSASSRMFLLVGAPKAN-TTQPGIVEGGQVLKCDWSST--RRCQPIEFDATGNRDYAKDD 114
Query: 119 -LEERDNQWLGVTLSRQPGENGSIVTCG--HRWKNIFYIKNENKLPTGGCYGVPPDLRTE 175
LE + +QW G ++ + I+ C + W+ +K E + P G C+
Sbjct: 115 PLEFKSHQWFGASVR---SKQDKILACAPLYHWRT--EMKQERE-PVGTCF--------- 159
Query: 176 LSKRIAPCYQDYVKKFGENFASCQAG-ISSFYTKDLIVMGAPGSSYWTGSLFVYNITTNK 234
QD K +A C++ + S +++ P VY+I N
Sbjct: 160 --------LQDGTKTV--EYAPCRSRQLISDQVAEIVSKYDPN---------VYSIKYNN 200
Query: 235 YKAFLDKQNQVKFGSYLGYSVGAGHFRSQHTTEVVGGAPQHEQ-IGKAYIFSIDEKELNI 293
A Q + SYLGYSV G F + V G P+ + +G YI+ D K ++
Sbjct: 201 QLATRTAQ-AIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIY--DGKNMSS 257
Query: 294 LHEMKGKKLGSYFGASVCAVDLNADGFSDLLVGAPM------QSTIREEGRVFVYINSGS 347
L+ G+++ +YFG SV A D+N D ++D+ +GAP+ ++E G+V V + S
Sbjct: 258 LYNFTGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQRAS 317
Query: 348 GAVMNAMETNLVGSDKYAARFGESIVNLGDIDNDGFEDVAIGAPQE-DDLQGAIYIYNGR 406
G + T L G + +A RFG +I LGD+D DGF D+AI AP +D +G +YI+NGR
Sbjct: 318 G---DFQTTKLNGFEVFA-RFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGR 373
Query: 407 ADGISSTFSQRIEGLQISKSLS-MFGQSISGQIDADNNGYVDVAVGAFRSDSAVLLRTRP 465
+ G+++ SQ +EG ++S+ FG S+ G D D NGY D+ VGAF D A+L R RP
Sbjct: 374 STGLNAVPSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARP 433
Query: 466 VVIVDASLS-HPESVNRTKFDCVENG--WPSVCIDLTLCFSYKGKEV-PGYIVLFYNMSL 521
V+ V+A L +P +N+ C G C ++ C GK V P + + L
Sbjct: 434 VITVNAGLEVYPSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLL 493
Query: 522 DVNRKAESPPRFYFSSNGTSDVITGSIQVSSREANCRTHQAFMR--KDVRDILTPIQIEA 579
D ++ + R F + + C A++R + RD LTPI I
Sbjct: 494 DKLKQKGAIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFM 553
Query: 580 AYHLGPHVISKRSTEEFPPLQPILQQKKEKDIMKKTINFARFCAHEN-CSADLQVSAKIG 638
Y L R+ + LQPIL Q +I ++ + C +N C L+VS
Sbjct: 554 EYRL-----DYRTAADTTGLQPILNQFTPANISRQA-HILLDCGEDNVCKPKLEVS---- 603
Query: 639 FLKPHENKTYLAVGSMKTLMLNVSLFNAGDDAYETTLHVKLPVGLYFIKILELEE--KQI 696
+ + K Y +G L L V N G+ AYE L V +P+ FI ++ E ++
Sbjct: 604 -VDSDQKKIY--IGDDNPLTLIVKAQNQGEGAYEAELIVSIPLQADFIGVVRNNEALARL 660
Query: 697 NCEVTDNSGVVQLDCSIGYIYVDHLSRIDISFLLDVSSLSRAEEDLSITVHATCENEEEM 756
+C + Q+ C +G + + L S ++E D S+ ++
Sbjct: 661 SCAFKTENQTRQVVCDLGN---PMKAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLF 717
Query: 757 DNLK---HSRVTVAIPLKYEVK---LTVHGFVNPTSFVYGSNDENEPETCMVEKMNLTFH 810
D + +V +A+ E++ H F+ ++ + N E E + V + +
Sbjct: 718 DKVSPVVSHKVDLAVLAAVEIRGVSSPDHIFLPIPNWEHKENPETEEDVGPV--VQHIYE 775
Query: 811 VINTGNSMAPNVSVEIMVPNSFSPQTDKLFNILDVQTTTGECHFENYQRVCALEQQKSAM 870
+ N G S + + P ++ T L IL G + + + L + S++
Sbjct: 776 LRNNGPSSFSKAMLHLQWPYKYNNNT--LLYILHYD-IDGPMNCTSDMEINPLRIKISSL 832
Query: 871 QTLK--GIVRFLSKTD----KRLLYCIKADPH--------CLNFLCNFGKMESGKEASVH 916
QT + V + D KR L + D H CL +C G+++ GK A ++
Sbjct: 833 QTTEKNDTVAGQGERDHLITKRDLALSEGDIHTLGCGVAQCLKIVCQVGRLDRGKSAILY 892
Query: 917 IQLEGRPSILEMDETSALKFEIRATG------FPEPNPRVIELNKDENVAHVLLEGLHHQ 970
++ E + ++++ FP N + ++ V + G+ Q
Sbjct: 893 VKSLLWTETFMNKENQNHSYSLKSSASFNVIEFPYKNLPIEDITNSTLVTTNVTWGI--Q 950
Query: 971 RPKRYFTIVIISSSLLLGLIVLLLISYVMWKAGFFKRQYKSILQEENRRDSWSYINSKSN 1030
+ +I ++L GL++L ++ +VM++ GFFKR + +E+ R + N + N
Sbjct: 951 PAPMPVPVWVIILAVLAGLLLLAVLVFVMYRMGFFKR-VRPPQEEQEREQLQPHENGEGN 1009
Query: 1031 DD 1032
+
Sbjct: 1010 SE 1011
>gi|222418611 integrin alpha 7 isoform 2 precursor [Homo sapiens]
Length = 1137
Score = 257 bits (657), Expect = 3e-68
Identities = 282/1067 (26%), Positives = 467/1067 (43%), Gaps = 126/1067 (11%)
Query: 34 YNVDTESALLYQGPHNTLFGYSVVLHSHGANR---WLLVGAPTANWLANASVINPGAIYR 90
+N+D AL +G +LFG+SV LH R WLLVGAP A L G ++
Sbjct: 34 FNLDVMGALRKEGEPGSLFGFSVALHRQLQPRPQSWLLVGAPQALALPGQQANRTGGLFA 93
Query: 91 CRIGKNPGQTCEQLQLGSPNGEPCGKTCLEERDNQWLGVTLSRQPGENGSIVTCGHRWKN 150
C + C ++ + G K E ++NQWLGV++ R G G IVTC HR++
Sbjct: 94 CPLSLEETD-CYRVDIDQ--GADMQK---ESKENQWLGVSV-RSQGPGGKIVTCAHRYEA 146
Query: 151 IFYIKN--ENKLPTGGCYGVPPDL--RTELSKRIAPCYQDYVKKFGENFASCQAGISSFY 206
+ E + G C+ + DL R EL + + E F CQ G ++ +
Sbjct: 147 RQRVDQILETRDMIGRCFVLSQDLAIRDELDGGEWKFCEGRPQGH-EQFGFCQQGTAAAF 205
Query: 207 TKD--LIVMGAPGSSYWTGSLFVYNITTNK-----YKAFLDKQNQVK-------FGSYLG 252
+ D ++ GAPG+ W G LFV NI ++ YK LD +++ SYLG
Sbjct: 206 SPDSHYLLFGAPGTYNWKGLLFVTNIDSSDPDQLVYKT-LDPADRLPGPAGDLALNSYLG 264
Query: 253 YSV--GAGHFRSQHTTEVVGGAPQHEQIGKAYIFSIDEKELNILHEM-KGKKLGSYFGAS 309
+S+ G G R++ + V GAP+ G I D + M G++L S FG S
Sbjct: 265 FSIDSGKGLVRAEELS-FVAGAPRANHKGAVVILRKDSASRLVPEVMLSGERLTSGFGYS 323
Query: 310 VCAVDLNADGFSDLLVGAPMQSTIREE--GRVFVYINSGSGAVMNAMETNLVGSDKYAAR 367
+ DLN+DG+ DL+VGAP +EE G V+VY+N G G L GS +
Sbjct: 324 LAVADLNSDGWPDLIVGAPYFFERQEELGGAVYVYLNQG-GHWAGISPLRLCGSPD--SM 380
Query: 368 FGESIVNLGDIDNDGFEDVAIGAPQEDDLQGAIYIYNGRADGISSTFSQRIEGLQISKSL 427
FG S+ LGD++ DGF D+A+GAP + D G ++IY+G + G+ + SQ +EG + +
Sbjct: 381 FGISLAVLGDLNQDGFPDIAVGAPFDGD--GKVFIYHGSSLGVVAKPSQVLEGEAV--GI 436
Query: 428 SMFGQSISGQIDADNNGYVDVAVGAFRSDSAVLLRTRPVVIVDASLS-HPESVNRTKFDC 486
FG S+SG +D D N Y D+ VG+ +D+AVL R RP++ V +S P S++ + +C
Sbjct: 437 KSFGYSLSGSLDMDGNQYPDLLVGSL-ADTAVLFRARPILHVSHEVSIAPRSIDLEQPNC 495
Query: 487 VENGWPSVCIDLTLCFSYKG--KEVPGYIVLFYNMSLDVNRKAESP-PRFYFSSNGTSD- 542
G SVC+DL +CFSY + L Y + D +R+ PR F S +
Sbjct: 496 A--GGHSVCVDLRVCFSYIAVPSSYSPTVALDYVLDADTDRRLRGQVPRVTFLSRNLEEP 553
Query: 543 --VITGSIQVS-SREANCRTHQAFMRKDVRDILTPIQIEAAYHL-GPHVISKRSTEEFPP 598
+G++ + + C ++++V+D L I + +Y L P + + + PP
Sbjct: 554 KHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVTLSYSLQTPRLRRQAPGQGLPP 613
Query: 599 LQPILQQKKEKDIMKKTINFARFCAHEN--CSADLQVSAKIGFLKPHENK---------- 646
+ PIL + + I+F + E+ C ++LQ+ + + +
Sbjct: 614 VAPIL-NAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRVSDTEFQPLPMDVDG 672
Query: 647 --TYLAVGSMKTLMLNVSLFNA----------GDDAYETTLHVKLPVGLYF--IKILELE 692
A+ + L + + N GDDA+E L V LP L++ ++ L+
Sbjct: 673 TTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLPDSLHYSGVRALDPA 732
Query: 693 EKQINCEVTDNSGVVQLDCSIGYIYVDHLSRIDISFLLDVSSLSRAEEDLSITVHATCEN 752
EK + N ++C +G + +++ +L S +S +L + + +
Sbjct: 733 EKPL---CLSNENASHVECELGN-PMKRGAQVTFYLILSTSGISIETTELEVELLLATIS 788
Query: 753 EEEMDNLK-HSRVTVAIPLKYEVKLTVHGFVNPTSFVYGSNDENE----PETCMVEKMNL 807
E+E+ + +RV + +P L++ G P + E E + K+
Sbjct: 789 EQELHPVSARARVFIELP------LSIAGMAIPQQLFFSGVVRGERAMQSERDVGSKVKY 842
Query: 808 TFHVINTGNSMAP--NVSVEIMVPNSFSPQTDKLF----------------------NIL 843
V N G S+ + + IM P+ + L+ NIL
Sbjct: 843 EVTVSNQGQSLRTLGSAFLNIMWPHEIANGKWLLYPMQVELEGGQGPGQKGLCSPRPNIL 902
Query: 844 DVQTTTGE---CHFENYQRVCALEQQKSAMQTLKGIVRFLSKTDKRLLYCIKADPHCLNF 900
+ + + E ++ E+Q+ +M V K L C + +C+ F
Sbjct: 903 HLDVDSRDRRRRELEPPEQQEPGERQEPSMSWWP--VSSAEKKKNITLDCARGTANCVVF 960
Query: 901 LCNFGKMESGKEASVHIQLEGRPSILEMDETSALKFEIRATGFPEPNPRVIELNKDENVA 960
C + V +L + E +L+ +RA + + + + L V
Sbjct: 961 SCPLYSFDRAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRANITVKSSIKNLMLRDASTVI 1020
Query: 961 HVLLEGLHHQRPKRYFTIVIISSSLLLGLIVLLLISYVMWKAGFFKR 1007
V++ +I ++L GL+VL L+ ++WK GFFKR
Sbjct: 1021 PVMVYLDPMAVVAEGVPWWVILLAVLAGLLVLALLVLLLWKMGFFKR 1067
>gi|222418613 integrin alpha 7 isoform 1 precursor [Homo sapiens]
Length = 1141
Score = 248 bits (634), Expect = 2e-65
Identities = 277/1070 (25%), Positives = 463/1070 (43%), Gaps = 128/1070 (11%)
Query: 34 YNVDTESALLYQGPHNTLFGYSVVLHSHGANR---WLLVGAPTANWLANASVINPGAIYR 90
+N+D AL +G +LFG+SV LH R WLLVGAP A L G ++
Sbjct: 34 FNLDVMGALRKEGEPGSLFGFSVALHRQLQPRPQSWLLVGAPQALALPGQQANRTGGLFA 93
Query: 91 CRIGKNPGQTCEQLQLGSPNGEPCGKTCLEERDNQWLGVTLSRQPGENGSIVTCGHRWKN 150
C + C ++ + G K E ++NQWLGV++ R G G IVTC HR++
Sbjct: 94 CPLSLEETD-CYRVDIDQ--GADMQK---ESKENQWLGVSV-RSQGPGGKIVTCAHRYEA 146
Query: 151 IFYIKN--ENKLPTGGCYGVPPDL--RTELSKRIAPCYQDYVKKFGENFASCQAGISSFY 206
+ E + G C+ + DL R EL + + E F CQ G ++ +
Sbjct: 147 RQRVDQILETRDMIGRCFVLSQDLAIRDELDGGEWKFCEGRPQGH-EQFGFCQQGTAAAF 205
Query: 207 TKD--LIVMGAPGSSYWTGSLFVY----------NITTNKYKAFLDKQNQ-----VKFGS 249
+ D ++ GAPG+ W G+ V ++ Y+A +K+ V S
Sbjct: 206 SPDSHYLLFGAPGTYNWKGTARVELCAQGSADLAHLDDGPYEAGGEKEQDPRLIPVPANS 265
Query: 250 YLGYSV--GAGHFRSQHTTEVVGGAPQHEQIGKAYIFSIDEKELNILHEM-KGKKLGSYF 306
Y G+S+ G G R++ + V GAP+ G I D + M G++L S F
Sbjct: 266 YFGFSIDSGKGLVRAEELS-FVAGAPRANHKGAVVILRKDSASRLVPEVMLSGERLTSGF 324
Query: 307 GASVCAVDLNADGFSDLLVGAPMQSTIREE--GRVFVYINSGSGAVMNAMETNLVGSDKY 364
G S+ DLN+DG+ DL+VGAP +EE G V+VY+N G G L GS
Sbjct: 325 GYSLAVADLNSDGWPDLIVGAPYFFERQEELGGAVYVYLNQG-GHWAGISPLRLCGSPD- 382
Query: 365 AARFGESIVNLGDIDNDGFEDVAIGAPQEDDLQGAIYIYNGRADGISSTFSQRIEGLQIS 424
+ FG S+ LGD++ DGF D+A+GAP + D G ++IY+G + G+ + SQ +EG +
Sbjct: 383 -SMFGISLAVLGDLNQDGFPDIAVGAPFDGD--GKVFIYHGSSLGVVAKPSQVLEGEAV- 438
Query: 425 KSLSMFGQSISGQIDADNNGYVDVAVGAFRSDSAVLLRTRPVVIVDASLS-HPESVNRTK 483
+ FG S+SG +D D N Y D+ VG+ +D+AVL R RP++ V +S P S++ +
Sbjct: 439 -GIKSFGYSLSGSLDMDGNQYPDLLVGSL-ADTAVLFRARPILHVSHEVSIAPRSIDLEQ 496
Query: 484 FDCVENGWPSVCIDLTLCFSYKG--KEVPGYIVLFYNMSLDVNRKAESP-PRFYFSSNGT 540
+C G SVC+DL +CFSY + L Y + D +R+ PR F S
Sbjct: 497 PNCA--GGHSVCVDLRVCFSYIAVPSSYSPTVALDYVLDADTDRRLRGQVPRVTFLSRNL 554
Query: 541 SD---VITGSIQVS-SREANCRTHQAFMRKDVRDILTPIQIEAAYHL-GPHVISKRSTEE 595
+ +G++ + + C ++++V+D L I + +Y L P + + +
Sbjct: 555 EEPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVTLSYSLQTPRLRRQAPGQG 614
Query: 596 FPPLQPILQQKKEKDIMKKTINFARFCAHEN--CSADLQVSAKIGFLKPHENK------- 646
PP+ PIL + + I+F + E+ C ++LQ+ + + +
Sbjct: 615 LPPVAPIL-NAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRVSDTEFQPLPMD 673
Query: 647 -----TYLAVGSMKTLMLNVSLFNA----------GDDAYETTLHVKLPVGLYF--IKIL 689
A+ + L + + N GDDA+E L V LP L++ ++ L
Sbjct: 674 VDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLPDSLHYSGVRAL 733
Query: 690 ELEEKQINCEVTDNSGVVQLDCSIGYIYVDHLSRIDISFLLDVSSLSRAEEDLSITVHAT 749
+ EK + N ++C +G + +++ +L S +S +L + +
Sbjct: 734 DPAEKPL---CLSNENASHVECELGN-PMKRGAQVTFYLILSTSGISIETTELEVELLLA 789
Query: 750 CENEEEMDNLK-HSRVTVAIPLKYEVKLTVHGFVNPTSFVYGSNDENE----PETCMVEK 804
+E+E+ + +RV + +P L++ G P + E E + K
Sbjct: 790 TISEQELHPVSARARVFIELP------LSIAGMAIPQQLFFSGVVRGERAMQSERDVGSK 843
Query: 805 MNLTFHVINTGNSMAP--NVSVEIMVPNSFSPQTDKLF---------------------- 840
+ V N G S+ + + IM P+ + L+
Sbjct: 844 VKYEVTVSNQGQSLRTLGSAFLNIMWPHEIANGKWLLYPMQVELEGGQGPGQKGLCSPRP 903
Query: 841 NILDVQTTTGE---CHFENYQRVCALEQQKSAMQTLKGIVRFLSKTDKRLLYCIKADPHC 897
NIL + + + E ++ E+Q+ +M V K L C + +C
Sbjct: 904 NILHLDVDSRDRRRRELEPPEQQEPGERQEPSMSWWP--VSSAEKKKNITLDCARGTANC 961
Query: 898 LNFLCNFGKMESGKEASVHIQLEGRPSILEMDETSALKFEIRATGFPEPNPRVIELNKDE 957
+ F C + V +L + E +L+ +RA + + + + L
Sbjct: 962 VVFSCPLYSFDRAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRANITVKSSIKNLMLRDAS 1021
Query: 958 NVAHVLLEGLHHQRPKRYFTIVIISSSLLLGLIVLLLISYVMWKAGFFKR 1007
V V++ +I ++L GL+VL L+ ++WK GFFKR
Sbjct: 1022 TVIPVMVYLDPMAVVAEGVPWWVILLAVLAGLLVLALLVLLLWKMGFFKR 1071
>gi|88758615 integrin alpha 2b preproprotein [Homo sapiens]
Length = 1039
Score = 248 bits (633), Expect = 2e-65
Identities = 285/1086 (26%), Positives = 458/1086 (42%), Gaps = 152/1086 (13%)
Query: 18 ETVMLLLC-LGVPTGRPYNVDTESALLYQGPHNTLFGYSVVLH--SHGANRWLLVGAPTA 74
E V+LLL P N+D Y GP+ + FG+S+ H SHG ++VGAP
Sbjct: 15 EWVLLLLGPCAAPPAWALNLDPVQLTFYAGPNGSQFGFSLDFHKDSHGRVA-IVVGAPRT 73
Query: 75 NWLANASVINPGAIYRCRIGKNPGQTCEQL--QLGSPNGEPCGKTCLEERDNQWLGVTLS 132
S G ++ C GQ C L L +T + Q LG ++
Sbjct: 74 ---LGPSQEETGGVFLCPWRAEGGQ-CPSLLFDLRDETRNVGSQTLQTFKARQGLGASVV 129
Query: 133 RQPGENGSIVTCG--HRWKNIFYIKNENKLPTGGCYGVPPDL--RTELSKRIAPCYQDYV 188
+ IV C W + + K P G C+ P+ R E S PC + +
Sbjct: 130 SW---SDVIVACAPWQHWNVLEKTEEAEKTPVGSCFLAQPESGRRAEYS----PCRGNTL 182
Query: 189 KK-FGENFAS-----CQAGISSFYTK-DLIVMGAPGSSYWTGSLF---VYNITTNKYKAF 238
+ + EN S C+AG SS T+ +V+GAPG Y+ G L V +I ++
Sbjct: 183 SRIYVENDFSWDKRYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVADIFSSYRPGI 242
Query: 239 L-----------DKQNQVKFGSYLGYSVGAGHFRSQ-HTTEVVGGAPQHE-QIGKAYIFS 285
L D N F Y GYSV G F +TTE V GAP +G I
Sbjct: 243 LLWHVSSQSLSFDSSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEIL- 301
Query: 286 IDEKELNILHEMKGKKLGSYFGASVCAVDLNADGFSDLLVGAPMQSTIR------EEGRV 339
+ LH ++G+++ SYFG SV D+N DG DLLVGAP+ R E GRV
Sbjct: 302 --DSYYQRLHRLRGEQMASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRADRKLAEVGRV 359
Query: 340 FVYINSGSGAVMNAMETNLVGSDKYAARFGESIVNLGDIDNDGFEDVAIGAPQEDDL-QG 398
++++ + A L G+ Y RFG +I LGD+D DG+ D+A+ AP +G
Sbjct: 360 YLFLQPRGPHALGAPSLLLTGTQLY-GRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRG 418
Query: 399 AIYIYNGRADGISSTFSQRIEGLQISKSLSMFGQSISGQIDADNNGYVDVAVGAFRSDSA 458
+ ++ G+++G+ S SQ ++ + S FG S+ G +D D+NGY D+ VGA+ ++
Sbjct: 419 QVLVFLGQSEGLRSRPSQVLD--SPFPTGSAFGFSLRGAVDIDDNGYPDLIVGAYGANQV 476
Query: 459 VLLRTRPVVIVDASLSHPESVNRTKFDCV--ENGWPSVCIDLTLCFSYKGKEVPGYIVLF 516
+ R +PVV L +S+N CV + P C ++ +C G +P + L
Sbjct: 477 AVYRAQPVVKASVQLLVQDSLNPAVKSCVLPQTKTPVSCFNIQMCVGATGHNIPQKLSL- 535
Query: 517 YNMSLDVNRKAESPPRFYFSSNGTSDVITGSIQVSSREAN-CRTHQAFMR--KDVRDILT 573
N L ++R+ R T ++ + + + C T AF+R D RD L+
Sbjct: 536 -NAELQLDRQKPRQGRRVLLLGSQQAGTTLNLDLGGKHSPICHTTMAFLRDEADFRDKLS 594
Query: 574 PIQIEAAYHLGPHVISKRSTEEFPPLQPILQQKKEKDIMKKTINFARFCAHEN-CSADLQ 632
PI + L P TE + P + + + ++T C ++ C LQ
Sbjct: 595 PIVLSLNVSLPP-------TE--AGMAPAVVLHGDTHVQEQT-RIVLDCGEDDVCVPQLQ 644
Query: 633 VSAKIGFLKPHENKTYLAVGSMKTLMLNVSLFNAGDDAYETTLHVKLPVGLYFIKILELE 692
++A + + L VG+ L L + N G+ AYE L V LP G ++++ L
Sbjct: 645 LTASV-------TGSPLLVGADNVLELQMDAANEGEGAYEAELAVHLPQGAHYMRALSNV 697
Query: 693 E--KQINCEVTDNSGVVQLDCSIGYIYVDHLSRIDISFLLDVSSLSRAEEDLSITVHATC 750
E +++ C + + C +G + ++I I+ L+ V +L A E +S +
Sbjct: 698 EGFERLICNQKKENETRVVLCELGNPMKKN-AQIGIAMLVSVGNLEEAGESVSFQLQIRS 756
Query: 751 ENEEEMDNLKHSRVTVAIPLKYEVKLTVHGFVNPTSFVYGSNDENEPETCMVE----KMN 806
+N + N V + +P++ E ++ + G P S V + +E E E ++ K+
Sbjct: 757 KNSQ---NPNSKIVLLDVPVRAEAQVELRGNSFPASLVVAA-EEGEREQNSLDSWGPKVE 812
Query: 807 LTFHVINTGNSMAPNVSVEIMVPNSFSPQTDKLFNILDVQTTTG-EC------------- 852
T+ + N G + + I +P P L ILD+Q G +C
Sbjct: 813 HTYELHNNGPGTVNGLHLSIHLPGQSQP--SDLLYILDIQPQGGLQCFPQPPVNPLKVDW 870
Query: 853 -------------HFENYQRVCAL--EQQKSAMQTLKGIVRFLSKTDKRLLYCIKADPHC 897
H + +R L +Q S +Q D L+ C A C
Sbjct: 871 GLPIPSPSPIHPAHHKRDRRQIFLPEPEQPSRLQ------------DPVLVSCDSAP--C 916
Query: 898 LNFLCNFGKMESGKEASVHI-------QLEGRPSILEMDETSALKFEIRATGFPEPNPRV 950
C+ +M G+ A V + L RP + ++ A + P P +
Sbjct: 917 TVVQCDLQEMARGQRAMVTVLAFLWLPSLYQRPLDQFVLQSHAW---FNVSSLPYAVPPL 973
Query: 951 IELNKDENVAHVLLEGLHHQRPKRYFTIVIISSSLLLGLIVLLLISYVMWKAGFFKRQYK 1010
+ V LL L + ++ +V +L GL++L ++ MWK GFFKR
Sbjct: 974 SLPRGEAQVWTQLLRALEERAIPIWWVLV----GVLGGLLLLTILVLAMWKVGFFKRNRP 1029
Query: 1011 SILQEE 1016
+ +++
Sbjct: 1030 PLEEDD 1035
>gi|4504747 integrin alpha 3 isoform a precursor [Homo sapiens]
Length = 1051
Score = 245 bits (625), Expect = 2e-64
Identities = 223/805 (27%), Positives = 379/805 (47%), Gaps = 76/805 (9%)
Query: 9 PGPRRAAVRETVMLL-LCLGVPTG----RPYNVDTESALLYQ-GPHNTLFGYSVVLHSHG 62
PGP RA +ML L L V G +N+DT ++ + G +LFGYSV LH
Sbjct: 3 PGPSRAPRAPRLMLCALALMVAAGGCVVSAFNLDTRFLVVKEAGNPGSLFGYSVALHRQT 62
Query: 63 ANRW---LLVGAPTANWLANASVINPGAIYRCRIGKNPGQTCEQLQLGSPNGEPCGKTCL 119
+ LL GAP + + GA+Y C + + CE++ + N G +
Sbjct: 63 ERQQRYLLLAGAPRELAVPDGYTNRTGAVYLCPLTAHKDD-CERMNITVKNDP--GHHII 119
Query: 120 EERDNQWLGVTLSRQPGENGSIVTCGHRWKNIFYIKNEN-KLPTGGCYGVPPDLRTELSK 178
E+ WLGVT++ Q G G ++ C HR+ + + +E+ + G CY DL + S
Sbjct: 120 ED---MWLGVTVASQ-GPAGRVLVCAHRYTQVLWSGSEDQRRMVGKCYVRGNDLELDSSD 175
Query: 179 RIAPCYQDYVKKFGENFAS--CQAGISSFYTKDLIVMGAPGSSYWTGSLFVYNITTNKYK 236
+ + + + CQ G S +T++ + GAPG+ W G+ ++
Sbjct: 176 DWQTYHNEMCNSNTDYLETGMCQLGTSGGFTQNTVYFGAPGAYNWKGNSYMIQRKEWDLS 235
Query: 237 AFLDKQNQVKFGSYLGYSVGAGHF-RSQHTTEVVGGAPQHEQIGKAYIFSIDEK-ELNIL 294
+ K + + Y+GY++ G F +V GAP+H +G ++ S + +L
Sbjct: 236 EYSYKDPEDQGNLYIGYTMQVGSFILHPKNITIVTGAPRHRHMGAVFLLSQEAGGDLRRR 295
Query: 295 HEMKGKKLGSYFGASVCAVDLNADGFSDLLVGAPMQSTIREE--GRVFVYINSGSGAVMN 352
++G ++G+YFG+++ DLN DG+ DLLVGAP +EE G ++V++N +G
Sbjct: 296 QVLEGSQVGAYFGSAIALADLNNDGWQDLLVGAPYYFERKEEVGGAIYVFMNQ-AGTSFP 354
Query: 353 AMETNLVGSDKYAARFGESIVNLGDIDNDGFEDVAIGAPQEDDLQGAIYIYNGRADGISS 412
A + L+ +A FG S+ ++GDI+ DGF+D+A+GAP E G +YIY+ + G+
Sbjct: 355 AHPSLLLHGPSGSA-FGLSVASIGDINQDGFQDIAVGAPFEG--LGKVYIYHSSSKGLLR 411
Query: 413 TFSQRIEGLQIS-KSLSMFGQSISGQIDADNNGYVDVAVGAFRSDSAVLLRTRPVVIVDA 471
Q I G ++ L+ FG S+SGQ+D D N Y D+ VG+ SD VLLR RPV+ +
Sbjct: 412 QPQQVIHGEKLGLPGLATFGYSLSGQMDVDENFYPDLLVGSL-SDHIVLLRARPVINIVH 470
Query: 472 SLSHPESVNRTKFDCVENGWPSVCIDLTLCFSY-KGKEVPGY---IVLFYNMSLDVNRKA 527
P C C+ + LCF+Y + P Y I L Y + D +R+
Sbjct: 471 KTLVPRPAVLDPALCTATS----CVQVELCFAYNQSAGNPNYRRNITLAYTLEADRDRR- 525
Query: 528 ESPPRFYFSSNGTSDVITGSIQVSSREANCRTHQAFMRKDVRDILTPIQIEAAYHLGPHV 587
PPR F+ + S V G S E C+ + + ++RD L PI I Y L +
Sbjct: 526 --PPRLRFAGS-ESAVFHGFF--SMPEMRCQKLELLLMDNLRDKLRPIIISMNYSLPLRM 580
Query: 588 -----ISKRSTEEFPPLQPILQQKKEKDIMKKTINFARFCAHEN-CSADLQVSAKIGFLK 641
+ RS + + PIL Q + + + F + C +N C ++LQ+ A F+
Sbjct: 581 PDRPRLGLRSLDAY----PILNQAQALE-NHTEVQFQKECGPDNKCESNLQMRA--AFVS 633
Query: 642 PHENKTYLAVGS--MKTLMLNVSLFN------AGDDAYETTLHVKLPVGLYFIKILELEE 693
+ K S ++ L+L++++ N +G+DA+E L + +P L +L
Sbjct: 634 EQQQKLSRLQYSRDVRKLLLSINVTNTRTSERSGEDAHEALLTLVVPPAL----LLSSVR 689
Query: 694 KQINCEVTDNSGVVQLDCSIGYIYVDHLSRIDISFLLDVSSLSRAEEDLSITVHATCENE 753
C+ + + C +G + + R+++ +V ++ DL + + + +
Sbjct: 690 PPGACQANET-----IFCELGNPFKRN-QRMELLIAFEVIGVTLHTRDLQVQLQLSTSSH 743
Query: 754 EEMDNLKHSRVTVAIPLKYEVKLTV 778
+ DNL +T+ + + L++
Sbjct: 744 Q--DNLWPMILTLLVDYTLQTSLSM 766
Score = 34.3 bits (77), Expect = 0.62
Identities = 19/42 (45%), Positives = 24/42 (57%), Gaps = 5/42 (11%)
Query: 978 IVIISSSLLLGLIVLLLISYVMWKAGFFKRQYKSILQEENRR 1019
+ + + LLLGLI+LLL WK GFFKR L E R+
Sbjct: 997 VAVGAGLLLLGLIILLL-----WKCGFFKRARTRALYEAKRQ 1033
>gi|6006011 integrin alpha 3 isoform b precursor [Homo sapiens]
Length = 1066
Score = 245 bits (625), Expect = 2e-64
Identities = 223/805 (27%), Positives = 379/805 (47%), Gaps = 76/805 (9%)
Query: 9 PGPRRAAVRETVMLL-LCLGVPTG----RPYNVDTESALLYQ-GPHNTLFGYSVVLHSHG 62
PGP RA +ML L L V G +N+DT ++ + G +LFGYSV LH
Sbjct: 3 PGPSRAPRAPRLMLCALALMVAAGGCVVSAFNLDTRFLVVKEAGNPGSLFGYSVALHRQT 62
Query: 63 ANRW---LLVGAPTANWLANASVINPGAIYRCRIGKNPGQTCEQLQLGSPNGEPCGKTCL 119
+ LL GAP + + GA+Y C + + CE++ + N G +
Sbjct: 63 ERQQRYLLLAGAPRELAVPDGYTNRTGAVYLCPLTAHKDD-CERMNITVKNDP--GHHII 119
Query: 120 EERDNQWLGVTLSRQPGENGSIVTCGHRWKNIFYIKNEN-KLPTGGCYGVPPDLRTELSK 178
E+ WLGVT++ Q G G ++ C HR+ + + +E+ + G CY DL + S
Sbjct: 120 ED---MWLGVTVASQ-GPAGRVLVCAHRYTQVLWSGSEDQRRMVGKCYVRGNDLELDSSD 175
Query: 179 RIAPCYQDYVKKFGENFAS--CQAGISSFYTKDLIVMGAPGSSYWTGSLFVYNITTNKYK 236
+ + + + CQ G S +T++ + GAPG+ W G+ ++
Sbjct: 176 DWQTYHNEMCNSNTDYLETGMCQLGTSGGFTQNTVYFGAPGAYNWKGNSYMIQRKEWDLS 235
Query: 237 AFLDKQNQVKFGSYLGYSVGAGHF-RSQHTTEVVGGAPQHEQIGKAYIFSIDEK-ELNIL 294
+ K + + Y+GY++ G F +V GAP+H +G ++ S + +L
Sbjct: 236 EYSYKDPEDQGNLYIGYTMQVGSFILHPKNITIVTGAPRHRHMGAVFLLSQEAGGDLRRR 295
Query: 295 HEMKGKKLGSYFGASVCAVDLNADGFSDLLVGAPMQSTIREE--GRVFVYINSGSGAVMN 352
++G ++G+YFG+++ DLN DG+ DLLVGAP +EE G ++V++N +G
Sbjct: 296 QVLEGSQVGAYFGSAIALADLNNDGWQDLLVGAPYYFERKEEVGGAIYVFMNQ-AGTSFP 354
Query: 353 AMETNLVGSDKYAARFGESIVNLGDIDNDGFEDVAIGAPQEDDLQGAIYIYNGRADGISS 412
A + L+ +A FG S+ ++GDI+ DGF+D+A+GAP E G +YIY+ + G+
Sbjct: 355 AHPSLLLHGPSGSA-FGLSVASIGDINQDGFQDIAVGAPFEG--LGKVYIYHSSSKGLLR 411
Query: 413 TFSQRIEGLQIS-KSLSMFGQSISGQIDADNNGYVDVAVGAFRSDSAVLLRTRPVVIVDA 471
Q I G ++ L+ FG S+SGQ+D D N Y D+ VG+ SD VLLR RPV+ +
Sbjct: 412 QPQQVIHGEKLGLPGLATFGYSLSGQMDVDENFYPDLLVGSL-SDHIVLLRARPVINIVH 470
Query: 472 SLSHPESVNRTKFDCVENGWPSVCIDLTLCFSY-KGKEVPGY---IVLFYNMSLDVNRKA 527
P C C+ + LCF+Y + P Y I L Y + D +R+
Sbjct: 471 KTLVPRPAVLDPALCTATS----CVQVELCFAYNQSAGNPNYRRNITLAYTLEADRDRR- 525
Query: 528 ESPPRFYFSSNGTSDVITGSIQVSSREANCRTHQAFMRKDVRDILTPIQIEAAYHLGPHV 587
PPR F+ + S V G S E C+ + + ++RD L PI I Y L +
Sbjct: 526 --PPRLRFAGS-ESAVFHGFF--SMPEMRCQKLELLLMDNLRDKLRPIIISMNYSLPLRM 580
Query: 588 -----ISKRSTEEFPPLQPILQQKKEKDIMKKTINFARFCAHEN-CSADLQVSAKIGFLK 641
+ RS + + PIL Q + + + F + C +N C ++LQ+ A F+
Sbjct: 581 PDRPRLGLRSLDAY----PILNQAQALE-NHTEVQFQKECGPDNKCESNLQMRA--AFVS 633
Query: 642 PHENKTYLAVGS--MKTLMLNVSLFN------AGDDAYETTLHVKLPVGLYFIKILELEE 693
+ K S ++ L+L++++ N +G+DA+E L + +P L +L
Sbjct: 634 EQQQKLSRLQYSRDVRKLLLSINVTNTRTSERSGEDAHEALLTLVVPPAL----LLSSVR 689
Query: 694 KQINCEVTDNSGVVQLDCSIGYIYVDHLSRIDISFLLDVSSLSRAEEDLSITVHATCENE 753
C+ + + C +G + + R+++ +V ++ DL + + + +
Sbjct: 690 PPGACQANET-----IFCELGNPFKRN-QRMELLIAFEVIGVTLHTRDLQVQLQLSTSSH 743
Query: 754 EEMDNLKHSRVTVAIPLKYEVKLTV 778
+ DNL +T+ + + L++
Sbjct: 744 Q--DNLWPMILTLLVDYTLQTSLSM 766
>gi|34452173 integrin alpha X precursor [Homo sapiens]
Length = 1163
Score = 233 bits (595), Expect = 5e-61
Identities = 235/848 (27%), Positives = 383/848 (45%), Gaps = 84/848 (9%)
Query: 199 QAGISSFYTKDLIVMGAPGSSYWTGSLFVYNITTNKYKAFLDKQNQVKFGSYLGYSVGAG 258
Q G S+ +T D V+GA GS W+G F+Y + + ++N SYLGYS
Sbjct: 353 QEGFSAVFTPDGPVLGAVGSFTWSGGAFLYPPNMSPTFINMSQENVDMRDSYLGYSTELA 412
Query: 259 HFRSQHTTEVVGGAPQHEQIGKAYIFSIDEKELNILHEMKGKKLGSYFGASVCAVDLNAD 318
++ + +V GAP+++ GKA IF+ ++ + E+ G ++GSYFGAS+C+VD+++D
Sbjct: 413 LWKGVQS--LVLGAPRYQHTGKAVIFTQVSRQWRMKAEVTGTQIGSYFGASLCSVDVDSD 470
Query: 319 GFSDL-LVGAPMQSTIREEGRVFVYINSGSGAVMNAMETNLVGSDKYA-ARFGESIVNLG 376
G +DL L+GAP G+V V G + L G + RFG ++ LG
Sbjct: 471 GSTDLVLIGAPHYYEQTRGGQVSV-CPLPRGWRRWWCDAVLYGEQGHPWGRFGAALTVLG 529
Query: 377 DIDNDGFEDVAIGAPQEDDLQGAIYIYNG-RADGISSTFSQRIEGLQISKSLSMFGQSIS 435
D++ D DV IGAP E++ +GA+Y+++G IS + SQRI G Q+S L FGQ++S
Sbjct: 530 DVNGDKLTDVVIGAPGEEENRGAVYLFHGVLGPSISPSHSQRIAGSQLSSRLQYFGQALS 589
Query: 436 GQIDADNNGYVDVAVGAFRSDSAVLLRTRPVVIVDASLSH-PESVNRTKFDC---VENGW 491
G D +G VD+AVGA +LLRTRPV+ V S+ P + R+ F+C V +
Sbjct: 590 GGQDLTQDGLVDLAVGA--RGQVLLLRTRPVLWVGVSMQFIPAEIPRSAFECREQVVSEQ 647
Query: 492 PSVCIDLTLCFSYKGKEVPGYIVLFYNMSLDVN-RKAESPPRFYFSSNGTSDVITGSIQV 550
V ++ L + K + G L +++LD+ PR F T + ++V
Sbjct: 648 TLVQSNICLYIDKRSKNLLGSRDLQSSVTLDLALDPGRLSPRATFQE--TKNRSLSRVRV 705
Query: 551 SSREANCRTHQAFMRKDVRDILTPIQIEAAYHL-GPHVISKRSTEEFPPLQPILQQKKEK 609
+A+C + V D +TPI + + L G +++ R+ L+P+L ++
Sbjct: 706 LGLKAHCENFNLLLPSCVEDSVTPITLRLNFTLVGKPLLAFRN------LRPMLAADAQR 759
Query: 610 DIMKKTINFARFCAHENCSADLQVSAKIGFLKPHENKTYLAVGSMKTLMLNVSLFNAGDD 669
A +NC AD +G L VGS L V ++N G+D
Sbjct: 760 YFT------ASLPFEKNCGADHICQDNLGISFSFPGLKSLLVGSNLELNAEVMVWNDGED 813
Query: 670 AYETTLHVKLPVGLYFIKILE------LEEKQINCE--VTDNSGVVQLDCSIGYIYVDHL 721
+Y TT+ P GL + + E L + C+ + G C I ++
Sbjct: 814 SYGTTITFSHPAGLSYRYVAEGQKQGQLRSLHLTCDSAPVGSQGTWSTSCRINHLIFRGG 873
Query: 722 SRIDISFLLDVSSLSRAEEDLSITVHATCENEEEMDNLKHSRVTVAIPLKYEVKLTVHGF 781
++I DVS + + L +T + + EN + + +P+KY V V
Sbjct: 874 AQITFLATFDVSPKAVLGDRLLLTANVSSEN--NTPRTSKTTFQLELPVKYAVYTVVSSH 931
Query: 782 VNPTSFV-YGSNDENEPETCMVEKMNLTFHVINTGNSMAPNVSVEIMVPNSFSPQTDKLF 840
T ++ + ++E E M + V N G P VS+ VP + +
Sbjct: 932 EQFTKYLNFSESEEKESHVAMHR-----YQVNNLGQRDLP-VSINFWVPVELNQEA---- 981
Query: 841 NILDVQTTTGECHFENYQRVCALEQQKSAMQTLKGIVRFLSKTDKR-LLYCIKADPHCLN 899
+DV+ + H +N C+ E+ FL+ K +L C A CL
Sbjct: 982 VWMDVEVS----HPQNPSLRCSSEKIAPPASD------FLAHIQKNPVLDCSIAG--CLR 1029
Query: 900 FLCNFGKMESGKEASVHIQLEGRPSILEMDETSALKFEIRATGFPEPNPRVIELNKDENV 959
F C+ +E + L+G S + + K + + V E+ D +V
Sbjct: 1030 FRCDVPSFSVQEE--LDFTLKGNLSFGWVRQILQKKVSVVS---------VAEITFDTSV 1078
Query: 960 AHVLLEGLHHQRPKRYFTIV----------IISSSLLLGLIVLLLISYVMWKAGFFKRQY 1009
+ L G + T++ +I S + GL++L LI+ V++K GFFKRQY
Sbjct: 1079 -YSQLPGQEAFMRAQTTTVLEKYKVHNPTPLIVGSSIGGLLLLALITAVLYKVGFFKRQY 1137
Query: 1010 KSILQEEN 1017
K +++E N
Sbjct: 1138 KEMMEEAN 1145
Score = 43.9 bits (102), Expect = 8e-04
Identities = 48/170 (28%), Positives = 77/170 (45%), Gaps = 28/170 (16%)
Query: 17 RETVMLLLCLGVPTGRPYNVDTESALLYQGPHNTLFGYSVVLHSHGANRWLLVGAPTANW 76
R LLL + T +N+DTE ++ + FG SVV + AN W++VGAP
Sbjct: 3 RTRAALLLFTALATSLGFNLDTEELTAFR-VDSAGFGDSVVQY---ANSWVVVGAPQKIT 58
Query: 77 LANASVINPGAIYRCRIGKNPGQTCEQLQLGSPNGEPCGKTCLEERDNQWLGVTLSRQPG 136
AN + G +Y+C G + G CE + L P E N LG++L+
Sbjct: 59 AANQT----GGLYQC--GYSTG-ACEPIGLQVP----------PEAVNMSLGLSLASTTS 101
Query: 137 ENGSIVTCGHRWKNIFYIKNENKLPTGGCYGVPPDLRTELSKRIAPCYQD 186
+ ++ CG + + N TG C+ + P T+L++R+ Q+
Sbjct: 102 PS-QLLACG---PTVHHECGRNMYLTGLCFLLGP---TQLTQRLPVSRQE 144
Score = 33.1 bits (74), Expect = 1.4
Identities = 40/144 (27%), Positives = 61/144 (42%), Gaps = 14/144 (9%)
Query: 198 CQAGISSFYTKDLIVMGAPGSSYWT--GSLFVYNITTNKYK----AFLDKQNQVKFGSYL 251
C + S + DL+++GAP T G + V + + A L + +G +
Sbjct: 463 CSVDVDSDGSTDLVLIGAPHYYEQTRGGQVSVCPLPRGWRRWWCDAVLYGEQGHPWGRFG 522
Query: 252 GYSVGAGHFRSQHTTEVVGGAP-QHEQIGKAYIF-SIDEKELNILHEMK--GKKLGS--- 304
G T+VV GAP + E G Y+F + ++ H + G +L S
Sbjct: 523 AALTVLGDVNGDKLTDVVIGAPGEEENRGAVYLFHGVLGPSISPSHSQRIAGSQLSSRLQ 582
Query: 305 YFGASVC-AVDLNADGFSDLLVGA 327
YFG ++ DL DG DL VGA
Sbjct: 583 YFGQALSGGQDLTQDGLVDLAVGA 606
>gi|31657142 integrin, alpha 1 precursor [Homo sapiens]
Length = 1179
Score = 233 bits (593), Expect = 9e-61
Identities = 225/857 (26%), Positives = 380/857 (44%), Gaps = 96/857 (11%)
Query: 199 QAGISSFYTKDLIVMGAPGSSYWTGSLFVYNIT------TNKYKAFLDKQNQVKFGSYLG 252
Q G S+ Y++D +++GA G+ W G++ + + + K+N+ SYLG
Sbjct: 379 QTGFSAHYSQDWVMLGAVGAYDWNGTVVMQKASQIIIPRNTTFNVESTKKNE-PLASYLG 437
Query: 253 YSVGAGHFRSQHTTEVVGGAPQHEQIGKAYIFSIDEKELNILHEMKGKKLGSYFGASVCA 312
Y+V + S + G P++ G+ I+ +++ + IL + G+++GSYFG+ +
Sbjct: 438 YTVNSATASSGDVL-YIAGQPRYNHTGQVIIYRMEDGNIKILQTLSGEQIGSYFGSILTT 496
Query: 313 VDLNADGFSD-LLVGAPMQ--STIREEGRVFVY-INSGSGAVMNAME------------- 355
D++ D +D LLVGAPM + E+G+V+VY +N ++E
Sbjct: 497 TDIDKDSNTDILLVGAPMYMGTEKEEQGKVYVYALNQTRFEYQMSLEPIKQTCCSSRQHN 556
Query: 356 --TNLVGSDKYAARFGESIVNLGDIDNDGFEDVAIGAPQEDDLQGAIYIYNGRADGISST 413
T ++ ARFG +I + D++ DGF D+ IGAP EDD GA+YIY+G I
Sbjct: 557 SCTTENKNEPCGARFGTAIAAVKDLNLDGFNDIVIGAPLEDDHGGAVYIYHGSGKTIRKE 616
Query: 414 FSQRIEGLQISKSLSMFGQSISGQIDADNNGYVDVAVGAFRSDSAVLLRTRPVVIVDASL 473
++QRI K+L FGQSI G++D + +G DV +G A L +R V +V ++
Sbjct: 617 YAQRIPSGGDGKTLKFFGQSIHGEMDLNGDGLTDVTIGGL--GGAALFWSRDVAVVKVTM 674
Query: 474 S-HPESVNRTKFDCVENGWPSVCIDLTLCFSYKGKEVPGYIV---LFYNMSLDVNRKAES 529
+ P VN K +C G +VCI+ T+CF K K I L Y ++LD R+
Sbjct: 675 NFEPNKVNIQKKNCHMEGKETVCINATVCFDVKLKSKEDTIYEADLQYRVTLDSLRQIS- 733
Query: 530 PPRFYFSSNGTSDVITGSIQVSSREANCRTHQAFMRKDVRDILTPIQIEAAYHLGPHVIS 589
R +FS V ++ R++ C H +M D D ++I ++L
Sbjct: 734 --RSFFSGTQERKV---QRNITVRKSECTKHSFYM-LDKHDFQDSVRITLDFNLTD---- 783
Query: 590 KRSTEEFPPLQPILQQKKEKDIMKKTINFARFCAH-ENCSADLQVSAKIGFLKPHENKTY 648
P P+L + + I FA+ C + E C +DL + K
Sbjct: 784 -------PENGPVLDDSLPNSV-HEYIPFAKDCGNKEKCISDLSLHVAT------TEKDL 829
Query: 649 LAVGSMKTLMLNVSLF--NAGDDAYETTLHVKLPVGLYFIKILELEEKQINCEVTDNSGV 706
L V S NVSL N D AY T V L F I +++ +CE N
Sbjct: 830 LIVRSQND-KFNVSLTVKNTKDSAYNTRTIVHYSPNLVFSGIEAIQKD--SCESNHN--- 883
Query: 707 VQLDCSIGYIYVDHLSRIDISFLLDVSSLSRAEEDLSITVHATCENEEEMDNLKHSRVTV 766
+ C +GY ++ + L ++ S E+++I + AT ++EE + L + V +
Sbjct: 884 --ITCKVGYPFLRRGEMVTFKILFQFNT-SYLMENVTIYLSATSDSEEPPETLSDNVVNI 940
Query: 767 AIPLKYEVKLTVHGFVNPTSFVYGSNDENEPETC-----MVEKMNLTFHVINTGNSMAPN 821
+IP+KYEV L + + +N E PE + ++N+ + + +G+ P
Sbjct: 941 SIPVKYEVGLQFYSSASEYHISIAAN-ETVPEVINSTEDIGNEINIFYLIRKSGSFPMPE 999
Query: 822 VSVEIMVPNSFSPQTDKLFNILDVQTTTGECHFENYQRVCALEQQKSAMQTLKGIVRFLS 881
+ + I PN S L+ + C ++ ++ K + +
Sbjct: 1000 LKLSISFPNMTSNGYPVLYPTGLSSSENANCRPHIFEDPFSINSGK----------KMTT 1049
Query: 882 KTDKRLLYCIKADPHCLNFLCNFGKMESGKEASVHIQL-EGRPSILEMDETSALKFEIRA 940
TD L D + F + S + V++ L +P+ ++ S+L IR
Sbjct: 1050 STD-HLKRGTILDCNTCKFATITCNLTSSDISQVNVSLILWKPTFIK-SYFSSLNLTIRG 1107
Query: 941 TGFPEPNPRVIELN--KDENVAHVLLEGLHHQRPKRYFTIVIISSSLLLGLIVLLLISYV 998
E V+ + K E + +GL + P + +I S GL++L+L+
Sbjct: 1108 ELRSENASLVLSSSNQKRELAIQISKDGLPGRVP-----LWVILLSAFAGLLLLMLLILA 1162
Query: 999 MWKAGFFKRQYKSILQE 1015
+WK GFFKR K +++
Sbjct: 1163 LWKIGFFKRPLKKKMEK 1179
Score = 63.9 bits (154), Expect = 7e-10
Identities = 51/183 (27%), Positives = 79/183 (43%), Gaps = 21/183 (11%)
Query: 1 MAWEARREPGPRRAAV-RETVMLLLCLGVPTGRPYNVDTESALLYQGPHNTLFGYSVVLH 59
MA R PG A TV+L C+ +NVD ++++ + GP +FGY+V +
Sbjct: 1 MAPRPRARPGVAVACCWLLTVVLRCCVS------FNVDVKNSMTFSGPVEDMFGYTVQQY 54
Query: 60 SHGANRWLLVGAPTANWLANASVINPGAIYRCRIGKNPGQTCEQLQLGSPNGEPCGKTCL 119
+ +W+L+G+P N + G +Y+C +G+ C +L L P
Sbjct: 55 ENEEGKWVLIGSPLVGQPKNRT----GDVYKCPVGRGESLPCVKLDLPVNTSIP---NVT 107
Query: 120 EERDNQWLGVTLSRQPGENGSIVTCGHRWKNIFYIKNENKLPTGGCYGVPPDLRTELSKR 179
E ++N G TL P NG + CG + Y TG C V P ++
Sbjct: 108 EVKENMTFGSTLVTNP--NGGFLACGPLYA---YRCGHLHYTTGICSDVSPTF--QVVNS 160
Query: 180 IAP 182
IAP
Sbjct: 161 IAP 163
>gi|62548866 integrin, alpha D precursor [Homo sapiens]
Length = 1161
Score = 216 bits (549), Expect = 1e-55
Identities = 228/840 (27%), Positives = 387/840 (46%), Gaps = 74/840 (8%)
Query: 199 QAGISSFYTKDLIVMGAPGSSYWTGSLFVYNITTNKYKAFLDKQNQVKFGSYLGYSVGAG 258
Q G S+ T D + +GA GS W+G F+Y + + ++N SYLGYS
Sbjct: 352 QEGFSTALTMDGLFLGAVGSFSWSGGAFLYPPNMSPTFINMSQENVDMRDSYLGYSTELA 411
Query: 259 HFRSQHTTEVVGGAPQHEQIGKAYIFSIDEKELNILHEMKGKKLGSYFGASVCAVDLNAD 318
++ +V GAP+++ GKA IF+ ++ E+ G ++GSYFGAS+C+VD+++D
Sbjct: 412 LWKG--VQNLVLGAPRYQHTGKAVIFTQVSRQWRKKAEVTGTQIGSYFGASLCSVDVDSD 469
Query: 319 GFSDL-LVGAPMQSTIREEGRVFVYINSGSGAVMNAMETNLVGSDKYA-ARFGESIVNLG 376
G +DL L+GAP G+V V G V + L G + RFG ++ LG
Sbjct: 470 GSTDLILIGAPHYYEQTRGGQVSV-CPLPRGRVQWQCDAVLRGEQGHPWGRFGAALTVLG 528
Query: 377 DIDNDGFEDVAIGAPQEDDLQGAIYIYNGRAD-GISSTFSQRIEGLQISKSLSMFGQSIS 435
D++ D DVAIGAP E + +GA+Y+++G ++ GIS + SQRI Q+S L FGQ++S
Sbjct: 529 DVNEDKLIDVAIGAPGEQENRGAVYLFHGASESGISPSHSQRIASSQLSPRLQYFGQALS 588
Query: 436 GQIDADNNGYVDVAVGAFRSDSAVLLRTRPVVIVDASLS-HPESVNRTKFDCVENGWPSV 494
G D +G +D+AVGA +LLR+ PV+ V ++ P V + + C E PS
Sbjct: 589 GGQDLTQDGLMDLAVGA--RGQVLLLRSLPVLKVGVAMRFSPVEVAKAVYRCWEEK-PSA 645
Query: 495 --CIDLTLCFSYKGKEVP--GYI--VLFYNMSLDVNRKAESPPRFYFSSNGTSDVITGSI 548
D T+C + + + G I + ++++LD R R F N T +
Sbjct: 646 LEAGDATVCLTIQKSSLDQLGDIQSSVRFDLALDPGRLTS---RAIF--NETKNPTLTRR 700
Query: 549 QVSSREANCRTHQAFMRKDVRDILTPIQIEAAYHLGPHVISKRSTEEFPPLQPILQQKKE 608
+ +C T + + V D+++PI + + L I L+P+L +
Sbjct: 701 KTLGLGIHCETLKLLLPDCVEDVVSPIILHLNFSLVREPIPSPQN-----LRPVLAVGSQ 755
Query: 609 KDIMKKTINFARFCAHEN-CSADLQVSAKIGFLKPHENKTYLAVGSMKTLMLNVSLFNAG 667
D+ ++ F + C + C DL V+ L+ L VGS L + V+++NAG
Sbjct: 756 -DLFTASLPFEKNCGQDGLCEGDLGVTLSFSGLQT------LTVGSSLELNVIVTVWNAG 808
Query: 668 DDAYETTLHVKLPVGLYFIKILELEEK------QINCEV--TDNSGVVQLDCSIGYIYVD 719
+D+Y T + + P GL ++ +++ ++ CE T++ G+ CS+ +
Sbjct: 809 EDSYGTVVSLYYPAGLSHRRVSGAQKQPHQSALRLACETVPTEDEGLRSSRCSVNHPIFH 868
Query: 720 HLSRIDISFLLDVSSLSRAEEDLSITVHATCENEEEMDNLKHSRVTVAIPLKYEVKLTVH 779
S DVS + + + + A+ EN + + + + +P+KY V +
Sbjct: 869 EGSNGTFIVTFDVSYKATLGDRMLMRASASSENNKASSS--KATFQLELPVKYAVYTMIS 926
Query: 780 GFVNPTS-FVYGSNDENEPETCMVEKMNLTFHVINTGNSMAPNVSVEIMVPNSFSPQTDK 838
T F + ++DE +KM H N ++++ I N + P
Sbjct: 927 RQEESTKYFNFATSDE--------KKMKEAEHRYRVNNLSQRDLAISI---NFWVP---V 972
Query: 839 LFNILDVQTTTGECHFENYQRVCALEQQKSAMQTLKGIVRFLSKTDKR-LLYCIKADPHC 897
L N + V E ++ C E++ FL++ + +L C AD C
Sbjct: 973 LLNGVAVWDVVMEAPSQSLP--CVSERKPPQHSD------FLTQISRSPMLDCSIAD--C 1022
Query: 898 LNFLCNFGKMESGKEASVHIQLEGRPSILEMDETSALKFEIRATGFPEPNPRVI-ELNKD 956
L F C+ +E + L+G S + ET K + + + V +L
Sbjct: 1023 LQFRCDVPSFSVQEE--LDFTLKGNLSFGWVRETLQKKVLVVSVAEITFDTSVYSQLPGQ 1080
Query: 957 ENVAHVLLEGLHHQRPKRYFTIVIISSSLLLGLIVLLLISYVMWKAGFFKRQYKSILQEE 1016
E +E + + + Y I II S + L++L LI+ ++K GFFKR YK +L+++
Sbjct: 1081 EAFMRAQME-MVLEEDEVYNAIPIIMGSSVGALLLLALITATLYKLGFFKRHYKEMLEDK 1139
Score = 30.8 bits (68), Expect = 6.9
Identities = 38/144 (26%), Positives = 58/144 (40%), Gaps = 14/144 (9%)
Query: 198 CQAGISSFYTKDLIVMGAPGSSYWT--GSLFVYNITTNKYK----AFLDKQNQVKFGSYL 251
C + S + DLI++GAP T G + V + + + A L + +G +
Sbjct: 462 CSVDVDSDGSTDLILIGAPHYYEQTRGGQVSVCPLPRGRVQWQCDAVLRGEQGHPWGRFG 521
Query: 252 GYSVGAGHFRSQHTTEVVGGAP-QHEQIGKAYIF-SIDEKELNILHEMK--GKKLG---S 304
G +V GAP + E G Y+F E ++ H + +L
Sbjct: 522 AALTVLGDVNEDKLIDVAIGAPGEQENRGAVYLFHGASESGISPSHSQRIASSQLSPRLQ 581
Query: 305 YFGASVC-AVDLNADGFSDLLVGA 327
YFG ++ DL DG DL VGA
Sbjct: 582 YFGQALSGGQDLTQDGLMDLAVGA 605
>gi|224831239 integrin alpha M isoform 1 precursor [Homo sapiens]
Length = 1153
Score = 212 bits (540), Expect = 1e-54
Identities = 223/862 (25%), Positives = 365/862 (42%), Gaps = 114/862 (13%)
Query: 199 QAGISSFYTKDLIVMGAPGSSYWTGSLFVYNITTNKYKAFLDKQNQVKFG---SYLGYSV 255
Q G S+ T + ++ GS W G +F+Y T+K K+ +V +YLGY+
Sbjct: 352 QEGFSAAITSNGPLLSTVGSYDWAGGVFLY---TSKEKSTFINMTRVDSDMNDAYLGYA- 407
Query: 256 GAGHFRSQHTTEVVGGAPQHEQIGKAYIFSIDEKELNILHEMKGKKLGSYFGASVCAVDL 315
A +V GAP+++ IG +F + +KG ++G+YFGAS+C+VD+
Sbjct: 408 -AAIILRNRVQSLVLGAPRYQHIGLVAMFRQNTGMWESNANVKGTQIGAYFGASLCSVDV 466
Query: 316 NADGFSDL-LVGAPMQSTIREEGRVFVYINSGSGAVMNAMETNLVGSDKYA-ARFGESIV 373
+++G +DL L+GAP G+V V + L G RFG ++
Sbjct: 467 DSNGSTDLVLIGAPHYYEQTRGGQVSVCPLPRGQRARWQCDAVLYGEQGQPWGRFGAALT 526
Query: 374 NLGDIDNDGFEDVAIGAPQEDDLQGAIYIYNGRA-DGISSTFSQRIEGLQISKSLSMFGQ 432
LGD++ D DVAIGAP E+D +GA+Y+++G + GIS + SQRI G ++S L FGQ
Sbjct: 527 VLGDVNGDKLTDVAIGAPGEEDNRGAVYLFHGTSGSGISPSHSQRIAGSKLSPRLQYFGQ 586
Query: 433 SISGQIDADNNGYVDVAVGAFRSDSAVLLRTRPVVIVDASLS-HPESVNRTKFDC----- 486
S+SG D +G VD+ VGA +LLR++PV+ V A + +P V R F+C
Sbjct: 587 SLSGGQDLTMDGLVDLTVGA--QGHVLLLRSQPVLRVKAIMEFNPREVARNVFECNDQVV 644
Query: 487 --VENGWPSVCIDLTLCFSYKGKEVPGYIVLFYNMSLDVNRKAESPPRFYFSSNGTSDVI 544
E G VC+ + + +E V+ Y+++LD R P N T +
Sbjct: 645 KGKEAGEVRVCLHVQKSTRDRLREGQIQSVVTYDLALDSGR-----PHSRAVFNETKNST 699
Query: 545 TGSIQVSSREANCRTHQAFMRKDVRDILTPIQIEAAYHLGPHVISKRSTEEFPPLQPILQ 604
QV C T + + + D ++PI + + L +S F L+P+L
Sbjct: 700 RRQTQVLGLTQTCETLKLQLPNCIEDPVSPIVLRLNFSLVGTPLS-----AFGNLRPVLA 754
Query: 605 QKKEKDIMKKTINFARFCAHEN-CSADLQVSAKIGFLKPHENKTYLAVGSMKTLMLNVSL 663
+ ++ + F + C ++N C DL ++ L L VG + + V++
Sbjct: 755 EDAQR-LFTALFPFEKNCGNDNICQDDLSITFSFMSL------DCLVVGGPREFNVTVTV 807
Query: 664 FNAGDDAYETTLHVKLPVGLYFIKILELEEK------QINCE---VTDNSGVVQ-LDCSI 713
N G+D+Y T + P+ L + K+ L+ + ++ CE T+ SG ++ CSI
Sbjct: 808 RNDGEDSYRTQVTFFFPLDLSYRKVSTLQNQRSQRSWRLACESASSTEVSGALKSTSCSI 867
Query: 714 GYIYVDHLSRIDISFLLDVSSLSRAEEDLSITVHATCENEEEMDNLKHSRVTVAIPLKYE 773
+ S + + DV S + L + + T EN M + + +P+KY
Sbjct: 868 NHPIFPENSEVTFNITFDVDSKASLGNKLLLKANVTSEN--NMPRTNKTEFQLELPVKYA 925
Query: 774 VKLTVHGFVNPTSFVYGSNDENEPETCMVEKMNLTFHVINTGNSMAPNVSVEIMVPNSFS 833
V + V T ++ + EN M + V N G P +S+ +VP +
Sbjct: 926 VYMVVTSHGVSTKYLNFTASENTSRV-----MQHQYQVSNLGQRSLP-ISLVFLVPVRLN 979
Query: 834 PQTDKLFNILDVQTTTGECHFENYQRVCALEQQKSAMQTLKGIVRFLSKTDKRLLYC--I 891
I D T EN C +++ + +R + + C I
Sbjct: 980 QTV-----IWDRPQVT---FSENLSSTCHTKERLPSHSDFLAELRKAPVVNCSIAVCQRI 1031
Query: 892 KADPHCLNFLCNFGKMESG--------KEASVHIQLEGRPSILEMDETSAL--------- 934
+ D F G K + H+ + IL D L
Sbjct: 1032 QCDIPFFGIQEEFNATLKGNLSFDWYIKTSHNHLLIVSTAEILFNDSVFTLLPGQGAFVR 1091
Query: 935 -KFEIRATGFPEPNPRVIELNKDENVAHVLLEGLHHQRPKRYFTIVIISSSLLLGLIVLL 993
+ E + F PNP + +I S + GL++L
Sbjct: 1092 SQTETKVEPFEVPNP-----------------------------LPLIVGSSVGGLLLLA 1122
Query: 994 LISYVMWKAGFFKRQYKSILQE 1015
LI+ ++K GFFKRQYK ++ E
Sbjct: 1123 LITAALYKLGFFKRQYKDMMSE 1144
Score = 32.7 bits (73), Expect = 1.8
Identities = 44/159 (27%), Positives = 71/159 (44%), Gaps = 27/159 (16%)
Query: 20 VMLLLCLGVPTGRPYNVDTESALLYQGPHNTLFGYSVVLHSHGANRWLLVGAPTANWLAN 79
V+LL L + G +N+DTE+A+ +Q + FG SVV G+ ++VGAP AN
Sbjct: 5 VLLLTALTLCHG--FNLDTENAMTFQ-ENARGFGQSVV-QLQGSR--VVVGAPQEIVAAN 58
Query: 80 ASVINPGAIYRCRIGKNPGQTCEQLQLGSPNGEPCGKTCLEERDNQWLGVTLSRQPGENG 139
G++Y+C +CE ++L P E N LG++L+
Sbjct: 59 ----QRGSLYQCDYSTG---SCEPIRLQVP----------VEAVNMSLGLSLAATTSP-P 100
Query: 140 SIVTCGHRWKNIFYIKNENKLPTGGCYGVPPDLRTELSK 178
++ CG + +EN G C+ +LR + K
Sbjct: 101 QLLACG---PTVHQTCSENTYVKGLCFLFGSNLRQQPQK 136
Score = 31.6 bits (70), Expect = 4.0
Identities = 39/145 (26%), Positives = 58/145 (40%), Gaps = 15/145 (10%)
Query: 198 CQAGISSFYTKDLIVMGAPGSSYWT--GSLFVYNITTN-----KYKAFLDKQNQVKFGSY 250
C + S + DL+++GAP T G + V + + A L + +G +
Sbjct: 462 CSVDVDSNGSTDLVLIGAPHYYEQTRGGQVSVCPLPRGQRARWQCDAVLYGEQGQPWGRF 521
Query: 251 LGYSVGAGHFRSQHTTEVVGGAP-QHEQIGKAYIF-SIDEKELNILHEMK--GKKLG--- 303
G T+V GAP + + G Y+F ++ H + G KL
Sbjct: 522 GAALTVLGDVNGDKLTDVAIGAPGEEDNRGAVYLFHGTSGSGISPSHSQRIAGSKLSPRL 581
Query: 304 SYFGASVC-AVDLNADGFSDLLVGA 327
YFG S+ DL DG DL VGA
Sbjct: 582 QYFGQSLSGGQDLTMDGLVDLTVGA 606
>gi|88501734 integrin alpha M isoform 2 precursor [Homo sapiens]
Length = 1152
Score = 212 bits (539), Expect = 2e-54
Identities = 224/862 (25%), Positives = 366/862 (42%), Gaps = 115/862 (13%)
Query: 199 QAGISSFYTKDLIVMGAPGSSYWTGSLFVYNITTNKYKAFLDKQNQVKFG---SYLGYSV 255
Q G S+ T + ++ GS W G +F+Y T+K K+ +V +YLGY+
Sbjct: 352 QEGFSAAITSNGPLLSTVGSYDWAGGVFLY---TSKEKSTFINMTRVDSDMNDAYLGYA- 407
Query: 256 GAGHFRSQHTTEVVGGAPQHEQIGKAYIFSIDEKELNILHEMKGKKLGSYFGASVCAVDL 315
A +V GAP+++ IG +F + +KG ++G+YFGAS+C+VD+
Sbjct: 408 -AAIILRNRVQSLVLGAPRYQHIGLVAMFRQNTGMWESNANVKGTQIGAYFGASLCSVDV 466
Query: 316 NADGFSDL-LVGAPMQSTIREEGRVFVYINSGSGAVMNAMETNLVGSDKYA-ARFGESIV 373
+++G +DL L+GAP G+V V G + L G RFG ++
Sbjct: 467 DSNGSTDLVLIGAPHYYEQTRGGQVSV-CPLPRGRARWQCDAVLYGEQGQPWGRFGAALT 525
Query: 374 NLGDIDNDGFEDVAIGAPQEDDLQGAIYIYNGRA-DGISSTFSQRIEGLQISKSLSMFGQ 432
LGD++ D DVAIGAP E+D +GA+Y+++G + GIS + SQRI G ++S L FGQ
Sbjct: 526 VLGDVNGDKLTDVAIGAPGEEDNRGAVYLFHGTSGSGISPSHSQRIAGSKLSPRLQYFGQ 585
Query: 433 SISGQIDADNNGYVDVAVGAFRSDSAVLLRTRPVVIVDASLS-HPESVNRTKFDC----- 486
S+SG D +G VD+ VGA +LLR++PV+ V A + +P V R F+C
Sbjct: 586 SLSGGQDLTMDGLVDLTVGA--QGHVLLLRSQPVLRVKAIMEFNPREVARNVFECNDQVV 643
Query: 487 --VENGWPSVCIDLTLCFSYKGKEVPGYIVLFYNMSLDVNRKAESPPRFYFSSNGTSDVI 544
E G VC+ + + +E V+ Y+++LD R P N T +
Sbjct: 644 KGKEAGEVRVCLHVQKSTRDRLREGQIQSVVTYDLALDSGR-----PHSRAVFNETKNST 698
Query: 545 TGSIQVSSREANCRTHQAFMRKDVRDILTPIQIEAAYHLGPHVISKRSTEEFPPLQPILQ 604
QV C T + + + D ++PI + + L +S F L+P+L
Sbjct: 699 RRQTQVLGLTQTCETLKLQLPNCIEDPVSPIVLRLNFSLVGTPLS-----AFGNLRPVLA 753
Query: 605 QKKEKDIMKKTINFARFCAHEN-CSADLQVSAKIGFLKPHENKTYLAVGSMKTLMLNVSL 663
+ ++ + F + C ++N C DL ++ L L VG + + V++
Sbjct: 754 EDAQR-LFTALFPFEKNCGNDNICQDDLSITFSFMSL------DCLVVGGPREFNVTVTV 806
Query: 664 FNAGDDAYETTLHVKLPVGLYFIKILELEEK------QINCE---VTDNSGVVQ-LDCSI 713
N G+D+Y T + P+ L + K+ L+ + ++ CE T+ SG ++ CSI
Sbjct: 807 RNDGEDSYRTQVTFFFPLDLSYRKVSTLQNQRSQRSWRLACESASSTEVSGALKSTSCSI 866
Query: 714 GYIYVDHLSRIDISFLLDVSSLSRAEEDLSITVHATCENEEEMDNLKHSRVTVAIPLKYE 773
+ S + + DV S + L + + T EN M + + +P+KY
Sbjct: 867 NHPIFPENSEVTFNITFDVDSKASLGNKLLLKANVTSEN--NMPRTNKTEFQLELPVKYA 924
Query: 774 VKLTVHGFVNPTSFVYGSNDENEPETCMVEKMNLTFHVINTGNSMAPNVSVEIMVPNSFS 833
V + V T ++ + EN M + V N G P +S+ +VP +
Sbjct: 925 VYMVVTSHGVSTKYLNFTASENTSRV-----MQHQYQVSNLGQRSLP-ISLVFLVPVRLN 978
Query: 834 PQTDKLFNILDVQTTTGECHFENYQRVCALEQQKSAMQTLKGIVRFLSKTDKRLLYC--I 891
I D T EN C +++ + +R + + C I
Sbjct: 979 QTV-----IWDRPQVT---FSENLSSTCHTKERLPSHSDFLAELRKAPVVNCSIAVCQRI 1030
Query: 892 KADPHCLNFLCNFGKMESG--------KEASVHIQLEGRPSILEMDETSAL--------- 934
+ D F G K + H+ + IL D L
Sbjct: 1031 QCDIPFFGIQEEFNATLKGNLSFDWYIKTSHNHLLIVSTAEILFNDSVFTLLPGQGAFVR 1090
Query: 935 -KFEIRATGFPEPNPRVIELNKDENVAHVLLEGLHHQRPKRYFTIVIISSSLLLGLIVLL 993
+ E + F PNP + +I S + GL++L
Sbjct: 1091 SQTETKVEPFEVPNP-----------------------------LPLIVGSSVGGLLLLA 1121
Query: 994 LISYVMWKAGFFKRQYKSILQE 1015
LI+ ++K GFFKRQYK ++ E
Sbjct: 1122 LITAALYKLGFFKRQYKDMMSE 1143
Score = 33.5 bits (75), Expect = 1.1
Identities = 39/144 (27%), Positives = 59/144 (40%), Gaps = 14/144 (9%)
Query: 198 CQAGISSFYTKDLIVMGAPGSSYWT--GSLFVYNITTNKYK----AFLDKQNQVKFGSYL 251
C + S + DL+++GAP T G + V + + + A L + +G +
Sbjct: 462 CSVDVDSNGSTDLVLIGAPHYYEQTRGGQVSVCPLPRGRARWQCDAVLYGEQGQPWGRFG 521
Query: 252 GYSVGAGHFRSQHTTEVVGGAP-QHEQIGKAYIF-SIDEKELNILHEMK--GKKLG---S 304
G T+V GAP + + G Y+F ++ H + G KL
Sbjct: 522 AALTVLGDVNGDKLTDVAIGAPGEEDNRGAVYLFHGTSGSGISPSHSQRIAGSKLSPRLQ 581
Query: 305 YFGASVC-AVDLNADGFSDLLVGA 327
YFG S+ DL DG DL VGA
Sbjct: 582 YFGQSLSGGQDLTMDGLVDLTVGA 605
Score = 32.7 bits (73), Expect = 1.8
Identities = 44/159 (27%), Positives = 71/159 (44%), Gaps = 27/159 (16%)
Query: 20 VMLLLCLGVPTGRPYNVDTESALLYQGPHNTLFGYSVVLHSHGANRWLLVGAPTANWLAN 79
V+LL L + G +N+DTE+A+ +Q + FG SVV G+ ++VGAP AN
Sbjct: 5 VLLLTALTLCHG--FNLDTENAMTFQ-ENARGFGQSVV-QLQGSR--VVVGAPQEIVAAN 58
Query: 80 ASVINPGAIYRCRIGKNPGQTCEQLQLGSPNGEPCGKTCLEERDNQWLGVTLSRQPGENG 139
G++Y+C +CE ++L P E N LG++L+
Sbjct: 59 ----QRGSLYQCDYSTG---SCEPIRLQVP----------VEAVNMSLGLSLAATTSP-P 100
Query: 140 SIVTCGHRWKNIFYIKNENKLPTGGCYGVPPDLRTELSK 178
++ CG + +EN G C+ +LR + K
Sbjct: 101 QLLACG---PTVHQTCSENTYVKGLCFLFGSNLRQQPQK 136
>gi|38569398 integrin, alpha 10 precursor [Homo sapiens]
Length = 1167
Score = 209 bits (531), Expect = 1e-53
Identities = 212/848 (25%), Positives = 373/848 (43%), Gaps = 84/848 (9%)
Query: 199 QAGISSFYTKDLIVMGAPGSSYWTGSLFVYNITTNKYKAFLDKQNQV-----KFGSYLGY 253
Q G S+ KD I+ G G+ W GS+ + + +++ +YLGY
Sbjct: 374 QIGFSTHRLKDGILFGMVGAYDWGGSVLWLEGGHRLFPPRMALEDEFPPALQNHAAYLGY 433
Query: 254 SVGAGHFRSQHTTEVVGGAPQHEQIGKAYIFSIDEK-ELNILHEMKGKKLGSYFGASVCA 312
SV + R + GAP+ GK F + + + + ++G+++GSYFG+ +C
Sbjct: 434 SVSSMLLRGGRRL-FLSGAPRFRHRGKVIAFQLKKDGAVRVAQSLQGEQIGSYFGSELCP 492
Query: 313 VDLNADGFSD-LLVGAPM--QSTIREEGRVFVYINSGSGAVMNAMETNLVGSDKYAARFG 369
+D + DG +D LLV APM +E GRV+VY+ + ++ L ARFG
Sbjct: 493 LDTDRDGTTDVLLVAAPMFLGPQNKETGRVYVYLVGQQSLL--TLQGTLQPEPPQDARFG 550
Query: 370 ESIVNLGDIDNDGFEDVAIGAPQEDDLQGAIYIYNGRADGISSTFSQRIEGLQISKSLSM 429
++ L D++ DGF DVA+GAP ED QGA+Y+Y+G G+ +QRI + +LS
Sbjct: 551 FAMGALPDLNQDGFADVAVGAPLEDGHQGALYLYHGTQSGVRPHPAQRIAAASMPHALSY 610
Query: 430 FGQSISGQIDADNNGYVDVAVGAFRSDSAVLLRTRPVVIVDASLS-HPESVNRTKFDCVE 488
FG+S+ G++D D + VDVAVGA +A+LL +RP+V + SL P++++ + DC
Sbjct: 611 FGRSVDGRLDLDGDDLVDVAVGA--QGAAILLSSRPIVHLTPSLEVTPQAISVVQRDCRR 668
Query: 489 NGWPSVCIDLTLCFSYKGKEVPGYIVLFYNMSLDVNRKAESPPRFYFSSNGTSDVITGSI 548
G +VC+ LCF + + FY + + R F +G + +
Sbjct: 669 RGQEAVCLTAALCFQVTSRTPGRWDHQFYMRFTASLDEWTAGARAAFDGSG-QRLSPRRL 727
Query: 549 QVSSREANCRTHQAFMRKDVRDILTPIQIEAAYHLGPHVISKRSTEEFPPLQPILQQKKE 608
++S C F D D L P+ + + L + P+L +
Sbjct: 728 RLSVGNVTCE-QLHFHVLDTSDYLRPVALTVTFAL----------DNTTKPGPVLNEGSP 776
Query: 609 KDIMKKTINFARFCAHEN-CSADLQVSAKIGFLKPHENKTYLAVGSMKTLMLNVSLFNAG 667
I +K + F++ C +N C DL + + ++ ++ G + ++++ +L N
Sbjct: 777 TSI-QKLVPFSKDCGPDNECVTDLVLQVNMD-IRGSRKAPFVVRGGRRKVLVSTTLENRK 834
Query: 668 DDAYETTLHVKLPVGLYFIKILELEEKQINCEVTDNSGVVQLDCSIGYIYVDHLSRIDIS 727
++AY T+L + L+ + E I E S +L CS+G+ + ++
Sbjct: 835 ENAYNTSLSLIFSRNLHLASLTPQRESPIKVECAAPSAHARL-CSVGHPVFQ--TGAKVT 891
Query: 728 FLLDVS-SLSRAEEDLSITVHATCENEEEMDNLKHSRVTVAIPLKYEVKL------TVHG 780
FLL+ S S + + + A+ ++ E L+ + + ++YE L T+H
Sbjct: 892 FLLEFEFSCSSLLSQVFVKLTASSDSLERNGTLQDNTAQTSAYIQYEPHLLFSSESTLHR 951
Query: 781 F-VNPTSFVYGSNDENE-PETCMVEKMNLTFHVINTGNSMAPNVSVEIMVPNSFSPQTDK 838
+ V+P YG+ PE T V N G + + + ++P + + +
Sbjct: 952 YEVHP----YGTLPVGPGPE------FKTTLRVQNLGCYVVSGLIISALLP-AVAHGGNY 1000
Query: 839 LFNILDVQTTTGECHFENYQRVCALEQQKSAMQTLKGIVRFLSKTDKRLLYCIKADPHCL 898
++ V T C +N +Q + ++ C
Sbjct: 1001 FLSLSQVITNNASCIVQNLTEPPGPPVHPEELQHTNRL--------------NGSNTQCQ 1046
Query: 899 NFLCNFGKMESGKEAS------VHIQLEGRPSILEMDETSALKFEIRATGFPEPNPRVIE 952
C+ G++ G E S VH + R + S FE+ G E + V++
Sbjct: 1047 VVRCHLGQLAKGTEVSVGLLRLVHNEFFRRAKFKSLTVVST--FEL---GTEEGS--VLQ 1099
Query: 953 LNKDENVAHVLLEGLHHQRPKRYFTIVIISSSLLLGLIVLLLISYVMWKAGFFKRQYKSI 1012
L + + LLE + Q ++ I+ S+L GL++L L+ + +WK GFF +K I
Sbjct: 1100 LTEASRWSESLLEVV--QTRPILISLWILIGSVLGGLLLLALLVFCLWKLGFF--AHKKI 1155
Query: 1013 LQEENRRD 1020
+EE R +
Sbjct: 1156 PEEEKREE 1163
Score = 57.8 bits (138), Expect = 5e-08
Identities = 38/116 (32%), Positives = 51/116 (43%), Gaps = 9/116 (7%)
Query: 33 PYNVDTESALLYQGPHNTLFGYSVVLHSHGANRWLLVGAPTANWLANASVINPGAIYRCR 92
P+N+D L+ GP FGYSV+ H G RW+LVGAP W S G +YRC
Sbjct: 22 PFNLDEHHPRLFPGPPEAEFGYSVLQHVGGGQRWMLVGAP---W-DGPSGDRRGDVYRCP 77
Query: 93 IGKNPGQTCEQLQLGSPNGEPCGKTCLEERDNQWLGVTLSRQPGENGSIVTCGHRW 148
+G C + LG + N LG++L G+ G + C W
Sbjct: 78 VGGAHNAPCAKGHLGDYQLGNSSHPAV----NMHLGMSLLETDGD-GGFMACAPLW 128
>gi|52485853 integrin, alpha 11 precursor [Homo sapiens]
Length = 1188
Score = 203 bits (517), Expect = 6e-52
Identities = 228/870 (26%), Positives = 377/870 (43%), Gaps = 129/870 (14%)
Query: 199 QAGISSFYTKDLIVMGAPGSSYWTGSLF-------VYNITTNKYKAFLDKQNQVKFGSYL 251
Q G SS +D +++GA G+ W G++ V + + K F ++ G+YL
Sbjct: 368 QTGFSSHVVEDGVLLGAVGAYDWNGAVLKETSAGKVIPLRESYLKEFPEELKN--HGAYL 425
Query: 252 GYSVGAGHFRSQHTTEVVGGAPQHEQIGKAYIFSI-DEKELNILHEMKGKKLGSYFGASV 310
GY+V S+ V GAP+ GK +F++ + + L I M+G+++GSYFG+ +
Sbjct: 426 GYTV-TSVVSSRQGRVYVAGAPRFNHTGKVILFTMHNNRSLTIHQAMRGQQIGSYFGSEI 484
Query: 311 CAVDLNADGFSD-LLVGAPMQ-STIREEGRVFVYINSGSGAVMNAMETNLVGSDKYA-AR 367
+VD++ DG +D LLVGAPM + RE G+V+VY + V N L S Y AR
Sbjct: 485 TSVDIDGDGVTDVLLVGAPMYFNEGRERGKVYVYELRQNLFVYNG---TLKDSHSYQNAR 541
Query: 368 FGESIVNLGDIDNDGFEDVAIGAPQEDDLQGAIYIYNGRADGISSTFSQRIEGLQISKSL 427
FG SI ++ D++ D + DV +GAP ED+ GAIYI++G I T QRI +++ L
Sbjct: 542 FGSSIASVRDLNQDSYNDVVVGAPLEDNHAGAIYIFHGFRGSILKTPKQRITASELATGL 601
Query: 428 SMFGQSISGQIDADNNGYVDVAVGAFRSDSAVLLRTRPVVIVDASLS-HPESVNRTKFDC 486
FG SI GQ+D + +G +D+AVGA +AV+L +RPVV ++ASL P +N DC
Sbjct: 602 QYFGCSIHGQLDLNEDGLIDLAVGAL--GNAVILWSRPVVQINASLHFEPSKINIFHRDC 659
Query: 487 VENGWPSVCIDLTLCFS--YKGKEVPGYIV-LFYNMSLDVNRKAESPPRFYFSSNGTSDV 543
+G + C+ LCF+ + V + YN ++D R PR + G D
Sbjct: 660 KRSGRDATCLAAFLCFTPIFLAPHFQTTTVGIRYNATMDERRYT---PRAHLDEGG--DR 714
Query: 544 ITG-SIQVSSREANCRTHQAFMRKDVRDILTPIQIEAAYHLGPHVISKRSTEEFPPLQPI 602
T ++ +SS + C F D D + P+ Y L E P P+
Sbjct: 715 FTNRAVLLSSGQELCERIN-FHVLDTADYVKPVTFSVEYSL-----------EDPDHGPM 762
Query: 603 LQQKKEKDIMKKTINFARFC-AHENCSADLQVSAK---------------------IGFL 640
L ++ ++ F C E+C DL + A+ +
Sbjct: 763 LDD-GWPTTLRVSVPFWNGCNEDEHCVPDLVLDARSDLPTAMEYCQRVLRKPAQDCSAYT 821
Query: 641 KPHENKTYLAVGSMKTLMLNVSLFNAGDDAYETTLHVKLPVGLYFIKILELEEKQINCEV 700
+ ++ + + + + +L N G++AY T L++ L F +++ E+ + E
Sbjct: 822 LSFDTTVFIIESTRQRVAVEATLENRGENAYSTVLNISQSANLQFASLIQKEDSDGSIEC 881
Query: 701 TDNSGVVQLD-CSIGYIYVDHLSRIDISFLLDVS-SLSRAEEDLSITVHATCENEEEMDN 758
+ +Q C++ Y + ++ ++F LD S S L I + A ++ E
Sbjct: 882 VNEERRLQKQVCNVSYPF--FRAKAKVAFRLDFEFSKSIFLHHLEIELAAGSDSNERDST 939
Query: 759 LKHSRVTVAIPLKYEVKLTV-------HGFVNPTSFVYGSNDENEPETCMVEKMNLTFHV 811
+ + + LKYE + H V P S + + P +C+ NL
Sbjct: 940 KEDNVAPLRFHLKYEADVLFTRSSSLSHYEVKPNSSLERYDGIGPPFSCIFRIQNLGLFP 999
Query: 812 INTGNSMAPNVSVEIMVPNSFSPQTDKLF-----------NILDVQTTTGECHFENYQRV 860
I+ G M + + N D L N + + T E E+ +R
Sbjct: 1000 IH-GMMMKITIPIATRSGNRLLKLRDFLTDEANTSCNIWGNSTEYRPTPVE---EDLRRA 1055
Query: 861 CALEQQKSAMQTLKGIVRFLSKTDKRLLYCIKADPHCLNFLCNFGKMESGKEASVHIQLE 920
L S + ++ +R + + H L L +++ K S+ I +
Sbjct: 1056 PQLNHSNSDVVSINCNIRLVPNQEINF--------HLLGNLW-LRSLKALKYKSMKIMV- 1105
Query: 921 GRPSILEMDETSALKFEIRATG-FPEPNPR---VIELNKDENVAHVLLEGLHHQRPKRYF 976
+AL+ + + F E +P V E++K E+ Q P
Sbjct: 1106 ----------NAALQRQFHSPFIFREEDPSRQIVFEISKQED----------WQVP---- 1141
Query: 977 TIVIISSSLLLGLIVLLLISYVMWKAGFFK 1006
I II S L GL++L L+ +WK GFF+
Sbjct: 1142 -IWIIVGSTLGGLLLLALLVLALWKLGFFR 1170
Score = 60.1 bits (144), Expect = 1e-08
Identities = 45/152 (29%), Positives = 65/152 (42%), Gaps = 17/152 (11%)
Query: 34 YNVDTESALLYQGPHNTLFGYSVVLHSHGANRWLLVGAPTANWLANASVINPGAIYRCRI 93
+N+DT + G FGY+V H N+WL+VGAP L G +Y+C +
Sbjct: 23 FNMDTRKPRVIPGSRTAFFGYTVQQHDISGNKWLVVGAP----LETNGYQKTGDVYKCPV 78
Query: 94 GKNPGQTCEQLQLGSPNGEPCGKTCLEERDNQWLGVTLSRQPGENGSIVTCGHRWKNIFY 153
C +L L G E +DN LG++L+ P +N S + C W +
Sbjct: 79 IHG---NCTKLNL----GRVTLSNVSERKDNMRLGLSLATNPKDN-SFLACSPLWS---H 127
Query: 154 IKNENKLPTGGCYGVPPDLRTELSKRIAPCYQ 185
+ TG C V + R SK +AP Q
Sbjct: 128 ECGSSYYTTGMCSRVNSNFR--FSKTVAPALQ 157
>gi|116295258 integrin alpha 2 precursor [Homo sapiens]
Length = 1181
Score = 201 bits (510), Expect = 4e-51
Identities = 213/872 (24%), Positives = 387/872 (44%), Gaps = 97/872 (11%)
Query: 192 GENFAS--CQAGISSFYTK--DLIVMGAPGSSYWTGSLFVYNITTNKY-----KAFLDKQ 242
G+NF Q G S+ Y+ D++++GA G+ W+G+ + T++ + +AF
Sbjct: 371 GDNFQMEMSQVGFSADYSSQNDILMLGAVGAFGWSGT--IVQKTSHGHLIFPKQAFDQIL 428
Query: 243 NQVKFGSYLGYSVGAGHFRSQHTTEVVGGAPQHEQIGKAYIFSIDEK-ELNILHEMKGKK 301
SYLGYSV A + +T V GAP+ G+ ++S++E + ++ +G +
Sbjct: 429 QDRNHSSYLGYSVAA--ISTGESTHFVAGAPRANYTGQIVLYSVNENGNITVIQAHRGDQ 486
Query: 302 LGSYFGASVCAVDLNADGFSD-LLVGAPMQSTI--REEGRVFVYINSGSGAVMNAMETNL 358
+GSYFG+ +C+VD++ D +D LLVGAPM + +EEGRV+++ ++ +
Sbjct: 487 IGSYFGSVLCSVDVDKDTITDVLLVGAPMYMSDLKKEEGRVYLF----------TIKEGI 536
Query: 359 VGSDKYA--------ARFGESIVNLGDIDNDGFEDVAIGAPQEDDLQGAIYIYNGRADGI 410
+G ++ RFG +I L DI+ DGF DV +G+P E+ GA+YIYNG I
Sbjct: 537 LGQHQFLEGPEGIENTRFGSAIAALSDINMDGFNDVIVGSPLENQNSGAVYIYNGHQGTI 596
Query: 411 SSTFSQRIEGLQ--ISKSLSMFGQSISGQIDADNNGYVDVAVGAFRSDSAVLLRTRPVVI 468
+ +SQ+I G L FG+S+ G D + + DV++GAF + ++ V
Sbjct: 597 RTKYSQKILGSDGAFRSHLQYFGRSLDGYGDLNGDSITDVSIGAFGQVVQLWSQSIADVA 656
Query: 469 VDASLSHPESVNRTKFDCVENGWPSVCIDLTLCFSYKGKEVP--GYIVLFYNMSLDVNR- 525
++AS + PE + + I L LCFS K + + + YN++LD +
Sbjct: 657 IEASFT-PEKITLVN--------KNAQIILKLCFSAKFRPTKQNNQVAIVYNITLDADGF 707
Query: 526 KAESPPRFYFSSNGTSDVITGSIQVSSREANCRTHQAFMRKDVRDILTPIQIEAAYHLGP 585
+ R F N ++ V ++ +C H ++ ++ D++ + + L
Sbjct: 708 SSRVTSRGLFKEN--NERCLQKNMVVNQAQSCPEHIIYI-QEPSDVVNSLDLRVDISL-- 762
Query: 586 HVISKRSTEEFPPLQPILQQKKEKDIMKKTINFARFCAHEN-CSADLQVSAKIGFLKPHE 644
E P P L+ E +I F + C + C +DL + + + +
Sbjct: 763 ---------ENPGTSPALEAYSE-TAKVFSIPFHKDCGEDGLCISDLVLDVR--QIPAAQ 810
Query: 645 NKTYLAVGSMKTLMLNVSLFNAGDDAYETTLHVKLPVGLYFIKI-LELEEKQINCEVTDN 703
+ ++ K L +V+L N + AY T + V L+F L ++ ++ C+V +
Sbjct: 811 EQPFIVSNQNKRLTFSVTLKNKRESAYNTGIVVDFSENLFFASFSLPVDGTEVTCQVAAS 870
Query: 704 SGVVQLDCSIGYIYVDHLSRIDISFLLDVSSLSRAEEDLSITVHATCENEEEMDNLKHSR 763
V C +GY + ++ + D +L + S++ A E++EE N +
Sbjct: 871 QKSVA--CDVGYPALKREQQVTFTINFDF-NLQNLQNQASLSFQALSESQEE--NKADNL 925
Query: 764 VTVAIPLKYEVKLTVHGFVNPTSFVYGSNDENEPETC-MVEKMNLTFHV---INTGNSMA 819
V + IPL Y+ ++ + N +F S+D N P E + F + TG+
Sbjct: 926 VNLKIPLLYDAEIHLTRSTN-INFYEISSDGNVPSIVHSFEDVGPKFIFSLKVTTGSVPV 984
Query: 820 PNVSVEIMVPNSFSPQTDKLFNILDVQT-TTGECHFENYQRVCALEQQKSAMQTLKGIVR 878
+V I +P ++ + + L + VQT G+ C + + V
Sbjct: 985 SMATVIIHIP-QYTKEKNPLMYLTGVQTDKAGDIS-------CNADINPLKIGQTSSSVS 1036
Query: 879 FLSKTDKRLLYCIKADPHCLNFLCNFGKMESGKEASVHIQLEGRPSILEMDETSALKFEI 938
F S+ + C N C + E V++ I S+ +
Sbjct: 1037 FKSENFRHTKELNCRTASCSNVTCWLKDVHMKGEYFVNVTTR----IWNGTFASSTFQTV 1092
Query: 939 RATGFPE---PNPRVIELNKDENVAHVLLEGLHHQRPKRYFTIVIISSSLLLGLIVLLLI 995
+ T E NP + + ++N + L + T VII S++ G+++LL +
Sbjct: 1093 QLTAAAEINTYNPEIYVI--EDNTVTIPLMIMKPDEKAEVPTGVII-GSIIAGILLLLAL 1149
Query: 996 SYVMWKAGFFKRQYKSILQEENRRDSWSYINS 1027
++WK GFFKR+Y+ + + + D + ++S
Sbjct: 1150 VAILWKLGFFKRKYEKMTKNPDEIDETTELSS 1181
Score = 67.8 bits (164), Expect = 5e-11
Identities = 77/292 (26%), Positives = 111/292 (38%), Gaps = 54/292 (18%)
Query: 10 GPRRAAVRETVMLLLCLGVPTG-----RPYNVDTESALLYQGPHNTLFGYSVVLHSHGAN 64
GP R + LLL L + G YNV A ++ GP + FGY+V +
Sbjct: 2 GPERTGAAP-LPLLLVLALSQGILNCCLAYNVGLPEAKIFSGPSSEQFGYAVQQFINPKG 60
Query: 65 RWLLVGAPTANWLANASVINPGAIYRCRIGKNPGQTCEQLQLGSPNGEPCGKTCLEERDN 124
WLLVG+P + + N G +Y+C + + TCE+L L + P E + N
Sbjct: 61 NWLLVGSPWSGFPEN----RMGDVYKCPVDLSTA-TCEKLNLQTSTSIP---NVTEMKTN 112
Query: 125 QWLGVTLSRQPGENGSIVTCGHRWK----NIFYIKNENKLPTGGCYGVPPD--LRTELSK 178
LG+ L+R G G +TCG W N +Y TG C + PD L S
Sbjct: 113 MSLGLILTRNMG-TGGFLTCGPLWAQQCGNQYY-------TTGVCSDISPDFQLSASFSP 164
Query: 179 RIAPCYQ-----------------DYVKKFGENFASCQAGISSFYTKDLIVMGAPGSSYW 221
PC D VK F E F G+ TK + + Y
Sbjct: 165 ATQPCPSLIDVVVVCDESNSIYPWDAVKNFLEKFVQ---GLDIGPTKTQVGL----IQYA 217
Query: 222 TGSLFVYNITTNKYK--AFLDKQNQVKFGSYLGYSVGAGHFRSQHTTEVVGG 271
V+N+ T K K + ++G L + GA + ++ G
Sbjct: 218 NNPRVVFNLNTYKTKEEMIVATSQTSQYGGDLTNTFGAIQYARKYAYSAASG 269
>gi|222418615 integrin alpha 7 isoform 3 [Homo sapiens]
Length = 1044
Score = 199 bits (505), Expect = 1e-50
Identities = 226/904 (25%), Positives = 389/904 (43%), Gaps = 113/904 (12%)
Query: 193 ENFASCQAGISSFYTKD--LIVMGAPGSSYWTGSLFVY----------NITTNKYKAFLD 240
E F CQ G ++ ++ D ++ GAPG+ W G+ V ++ Y+A +
Sbjct: 95 EQFGFCQQGTAAAFSPDSHYLLFGAPGTYNWKGTARVELCAQGSADLAHLDDGPYEAGGE 154
Query: 241 KQNQ-----VKFGSYLGYSV--GAGHFRSQHTTEVVGGAPQHEQIGKAYIFSIDEKELNI 293
K+ V SY G+S+ G G R++ + V GAP+ G I D +
Sbjct: 155 KEQDPRLIPVPANSYFGFSIDSGKGLVRAEELS-FVAGAPRANHKGAVVILRKDSASRLV 213
Query: 294 LHEM-KGKKLGSYFGASVCAVDLNADGFSDLLVGAPMQSTIREE--GRVFVYINSGSGAV 350
M G++L S FG S+ DLN+DG+ DL+VGAP +EE G V+VY+N G G
Sbjct: 214 PEVMLSGERLTSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEELGGAVYVYLNQG-GHW 272
Query: 351 MNAMETNLVGSDKYAARFGESIVNLGDIDNDGFEDVAIGAPQEDDLQGAIYIYNGRADGI 410
L GS + FG S+ LGD++ DGF D+A+GAP + D G ++IY+G + G+
Sbjct: 273 AGISPLRLCGSPD--SMFGISLAVLGDLNQDGFPDIAVGAPFDGD--GKVFIYHGSSLGV 328
Query: 411 SSTFSQRIEGLQISKSLSMFGQSISGQIDADNNGYVDVAVGAFRSDSAVLLRTRPVVIVD 470
+ SQ +EG + + FG S+SG +D D N Y D+ VG+ +D+AVL R RP++ V
Sbjct: 329 VAKPSQVLEGEAV--GIKSFGYSLSGSLDMDGNQYPDLLVGSL-ADTAVLFRARPILHVS 385
Query: 471 ASLS-HPESVNRTKFDCVENGWPSVCIDLTLCFSYKG--KEVPGYIVLFYNMSLDVNRKA 527
+S P S++ + +C G SVC+DL +CFSY + L Y + D +R+
Sbjct: 386 HEVSIAPRSIDLEQPNCA--GGHSVCVDLRVCFSYIAVPSSYSPTVALDYVLDADTDRRL 443
Query: 528 ESP-PRFYFSSNGTSD---VITGSIQVS-SREANCRTHQAFMRKDVRDILTPIQIEAAYH 582
PR F S + +G++ + + C ++++V+D L I + +Y
Sbjct: 444 RGQVPRVTFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVTLSYS 503
Query: 583 L-GPHVISKRSTEEFPPLQPILQQKKEKDIMKKTINFARFCAHEN--CSADLQVSAKIGF 639
L P + + + PP+ PIL + + I+F + E+ C ++LQ+
Sbjct: 504 LQTPRLRRQAPGQGLPPVAPIL-NAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFC 562
Query: 640 LKPHENK------------TYLAVGSMKTLMLNVSLFNA----------GDDAYETTLHV 677
+ + + A+ + L + + N GDDA+E L V
Sbjct: 563 TRVSDTEFQPLPMDVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLV 622
Query: 678 KLPVGLYF--IKILELEEKQINCEVTDNSGVVQLDCSIGYIYVDHLSRIDISFLLDVSSL 735
LP L++ ++ L+ EK + N ++C +G + +++ +L S +
Sbjct: 623 MLPDSLHYSGVRALDPAEKPL---CLSNENASHVECELGN-PMKRGAQVTFYLILSTSGI 678
Query: 736 SRAEEDLSITVHATCENEEEMDNLK-HSRVTVAIPLKYEVKLTVHGFVNPTSFVYGSNDE 794
S +L + + +E+E+ + +RV + +P L++ G P +
Sbjct: 679 SIETTELEVELLLATISEQELHPVSARARVFIELP------LSIAGMAIPQQLFFSGVVR 732
Query: 795 NE----PETCMVEKMNLTFHVINTGNSMAP--NVSVEIMVPNSFSPQTDKLF-------- 840
E E + K+ V N G S+ + + IM P+ + L+
Sbjct: 733 GERAMQSERDVGSKVKYEVTVSNQGQSLRTLGSAFLNIMWPHEIANGKWLLYPMQVELEG 792
Query: 841 --------------NILDVQTTTGE---CHFENYQRVCALEQQKSAMQTLKGIVRFLSKT 883
NIL + + + E ++ E+Q+ +M V K
Sbjct: 793 GQGPGQKGLCSPRPNILHLDVDSRDRRRRELEPPEQQEPGERQEPSMSWWP--VSSAEKK 850
Query: 884 DKRLLYCIKADPHCLNFLCNFGKMESGKEASVHIQLEGRPSILEMDETSALKFEIRATGF 943
L C + +C+ F C + V +L + E +L+ +RA
Sbjct: 851 KNITLDCARGTANCVVFSCPLYSFDRAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRANIT 910
Query: 944 PEPNPRVIELNKDENVAHVLLEGLHHQRPKRYFTIVIISSSLLLGLIVLLLISYVMWKAG 1003
+ + + + L V V++ +I ++L GL+VL L+ ++WK G
Sbjct: 911 VKSSIKNLMLRDASTVIPVMVYLDPMAVVAEGVPWWVILLAVLAGLLVLALLVLLLWKMG 970
Query: 1004 FFKR 1007
FFKR
Sbjct: 971 FFKR 974
>gi|167466217 integrin alpha L isoform b precursor [Homo sapiens]
Length = 1086
Score = 198 bits (504), Expect = 2e-50
Identities = 228/874 (26%), Positives = 392/874 (44%), Gaps = 100/874 (11%)
Query: 171 DLRTELSKRI----APCYQDYVKKFGENFASCQAGISSFYTKDLIVMGAPGSSYWTGSLF 226
DL TEL K+I QD N +GIS+ ++ V+GA G+ W G
Sbjct: 239 DLFTELQKKIYVIEGTSKQDLTSF---NMELSSSGISADLSRGHAVVGAVGAKDWAGGFL 295
Query: 227 VYNITTNKYKAFLDKQN---QVKFGSYLGYSVGAGHFRSQHTTEVVGGAPQHEQIGKAYI 283
F+ + +V+ G YLGY+V R Q T+ + GAP+++ +G+ +
Sbjct: 296 DLKADLQD-DTFIGNEPLTPEVRAG-YLGYTVTWLPSR-QKTSLLASGAPRYQHMGRVLL 352
Query: 284 FSIDE-----KELNILHEMKGKKLGSYFGASVCAVDLNADGFSDLL-VGAPMQSTIREEG 337
F + ++ +H G ++GSYFG +C VD++ DG ++LL +GAP+ + G
Sbjct: 353 FQEPQGGGHWSQVQTIH---GTQIGSYFGGELCGVDVDQDGETELLLIGAPLFYGEQRGG 409
Query: 338 RVFVYINSGSGAVMNAMETNLVGSDKYA-ARFGESIVNLGDIDNDGFEDVAIGAPQEDDL 396
RVF+Y G + L G Y RFGE+I L DI+ DG DVA+GAP E+
Sbjct: 410 RVFIYQRRQLGF---EEVSELQGDPGYPLGRFGEAITALTDINGDGLVDVAVGAPLEE-- 464
Query: 397 QGAIYIYNGRADGISSTFSQRIEGLQISKSLSMFGQSISGQIDADNNGYVDVAVGAFRSD 456
QGA+YI+NGR G+S SQRIEG Q+ + FG+SI G D + +G DVAVGA
Sbjct: 465 QGAVYIFNGRHGGLSPQPSQRIEGTQVLSGIQWFGRSIHGVKDLEGDGLADVAVGA--ES 522
Query: 457 SAVLLRTRPVVIVDASLSH-PESVNRTKFDCVENGWPSVC--IDLTLCFSYKG--KEVPG 511
++L +RPVV + +S P + + +C + + +++T+CF K + G
Sbjct: 523 QMIVLSSRPVVDMVTLMSFSPAEIPVHEVECSYSTSNKMKEGVNITICFQIKSLIPQFQG 582
Query: 512 YIV--LFYNMSLDVNRKAESPPRFYFSSNGTSDVITGSIQVSSREANCRTHQAFMRKDVR 569
+V L Y + LD +R R F G + +I V++ +C V+
Sbjct: 583 RLVANLTYTLQLDGHRTRR---RGLFP--GGRHELRRNIAVTT-SMSCTDFSFHFPVCVQ 636
Query: 570 DILTPIQIEAAYHLGPHVISKRSTEEFPPLQPILQQKKEKDIMKKTINFARFCAHEN-CS 628
D+++PI + + L + R + PIL+ + + I F + C + C
Sbjct: 637 DLISPINVSLNFSLWEEEGTPRDQRAGKDIPPILRPSLHSETWE--IPFEKNCGEDKKCE 694
Query: 629 ADLQVSAKIGFLKPHENKTYLAVGSMKTLMLNVSLFNAGDDAYETTLHVKLPVGLYFIKI 688
A+L+VS P ++ L + + +L + +SL N +DAY L + P GL F K+
Sbjct: 695 ANLRVS-----FSPARSRA-LRLTAFASLSVELSLSNLEEDAYWVQLDLHFPPGLSFRKV 748
Query: 689 LELEEKQ---INCE-VTDNSGVVQ--LDCSIGYIYVDHLSRIDISFLLDVSSLSRAEEDL 742
L+ ++CE + + S ++ L C++ + + + + S + +
Sbjct: 749 EMLKPHSQIPVSCEELPEESRLLSRALSCNVSSPIFKAGHSVALQMMFNTLVNSSWGDSV 808
Query: 743 SITVHATCENEEEMDNLKHSRVTVAIPLKYEVKLTVHGFVNPTSFVYGSNDENEPETCMV 802
+ + TC NE+ D L+ + T IP+ Y + + + + T +Y S P+ V
Sbjct: 809 ELHANVTCNNEDS-DLLEDNSATTIIPILYPINILIQDQEDST--LYVSFTPKGPKIHQV 865
Query: 803 EKMNLTFHVINTGNSMAPNVSVEIMVPNSFSPQTDKLFNILDVQTTTG-ECHFENYQRVC 861
+ M + + P + + VP P + + VQ CH+E+
Sbjct: 866 KHMYQVRIQPSIHDHNIPTLEAVVGVPQP--PSEGPITHQWSVQMEPPVPCHYED----- 918
Query: 862 ALEQQKSAMQTLKGIVRFLSKTDKRLLYCIKADPHCLNFLCNFGKMESGKEASVHIQLEG 921
LE+ A + F R ++ + L G++E+ S+
Sbjct: 919 -LERLPDAAEPCLPGALFRCPVVFRQEILVQV----IGTLELVGEIEASSMFSLC----- 968
Query: 922 RPSILEMDETSALKFEIRATGFPEPNPRVIELNKDENVAHVLLE-GLHHQRPKRYFTIVI 980
S L + S+ F + + + ++A V+++ + +++ Y ++
Sbjct: 969 --SSLSISFNSSKHFHLYGS--------------NASLAQVVMKVDVVYEKQMLYLYVL- 1011
Query: 981 ISSSLLLGLIVLLLISYVMWKAGFFKRQYKSILQ 1014
S + GL++LLLI V++K GFFKR K ++
Sbjct: 1012 ---SGIGGLLLLLLIFIVLYKVGFFKRNLKEKME 1042
>gi|167466215 integrin alpha L isoform a precursor [Homo sapiens]
Length = 1170
Score = 195 bits (495), Expect = 2e-49
Identities = 228/875 (26%), Positives = 393/875 (44%), Gaps = 101/875 (11%)
Query: 171 DLRTELSKRI----APCYQDYVKKFGENFASCQAGISSFYTKDLIVMGAPGSSYWTGSLF 226
DL TEL K+I QD N +GIS+ ++ V+GA G+ W G
Sbjct: 322 DLFTELQKKIYVIEGTSKQDLTSF---NMELSSSGISADLSRGHAVVGAVGAKDWAGGFL 378
Query: 227 VYNITTNKYKAFLDKQN---QVKFGSYLGYSVGAGHFRSQHTTEVVGGAPQHEQIGKAYI 283
F+ + +V+ G YLGY+V R Q T+ + GAP+++ +G+ +
Sbjct: 379 DLKADLQD-DTFIGNEPLTPEVRAG-YLGYTVTWLPSR-QKTSLLASGAPRYQHMGRVLL 435
Query: 284 FSIDE-----KELNILHEMKGKKLGSYFGASVCAVDLNADGFSDLL-VGAPMQSTIREEG 337
F + ++ +H G ++GSYFG +C VD++ DG ++LL +GAP+ + G
Sbjct: 436 FQEPQGGGHWSQVQTIH---GTQIGSYFGGELCGVDVDQDGETELLLIGAPLFYGEQRGG 492
Query: 338 RVFVYINSGSGAVMNAMETNLVGSDKYA-ARFGESIVNLGDIDNDGFEDVAIGAPQEDDL 396
RVF+Y G + L G Y RFGE+I L DI+ DG DVA+GAP E+
Sbjct: 493 RVFIYQRRQLGF---EEVSELQGDPGYPLGRFGEAITALTDINGDGLVDVAVGAPLEE-- 547
Query: 397 QGAIYIYNGRADGISSTFSQRIEGLQISKSLSMFGQSISGQIDADNNGYVDVAVGAFRSD 456
QGA+YI+NGR G+S SQRIEG Q+ + FG+SI G D + +G DVAVGA
Sbjct: 548 QGAVYIFNGRHGGLSPQPSQRIEGTQVLSGIQWFGRSIHGVKDLEGDGLADVAVGA--ES 605
Query: 457 SAVLLRTRPVVIVDASLSH-PESVNRTKFDCVENGWPSVC--IDLTLCFSYKG--KEVPG 511
++L +RPVV + +S P + + +C + + +++T+CF K + G
Sbjct: 606 QMIVLSSRPVVDMVTLMSFSPAEIPVHEVECSYSTSNKMKEGVNITICFQIKSLIPQFQG 665
Query: 512 YIV--LFYNMSLDVNRKAESPPRFYFSSNGTSDVITGSIQVSSREANCRTHQAFMRKDVR 569
+V L Y + LD +R R F G + +I V++ +C V+
Sbjct: 666 RLVANLTYTLQLDGHRTRR---RGLFP--GGRHELRRNIAVTT-SMSCTDFSFHFPVCVQ 719
Query: 570 DILTPIQIEAAYHLGPHVISKRSTE-EFPPLQPILQQKKEKDIMKKTINFARFCAHEN-C 627
D+++PI + + L + R + + PIL+ + + I F + C + C
Sbjct: 720 DLISPINVSLNFSLWEEEGTPRDQRAQGKDIPPILRPSLHSETWE--IPFEKNCGEDKKC 777
Query: 628 SADLQVSAKIGFLKPHENKTYLAVGSMKTLMLNVSLFNAGDDAYETTLHVKLPVGLYFIK 687
A+L+VS P ++ L + + +L + +SL N +DAY L + P GL F K
Sbjct: 778 EANLRVS-----FSPARSRA-LRLTAFASLSVELSLSNLEEDAYWVQLDLHFPPGLSFRK 831
Query: 688 ILELEEKQ---INCE-VTDNSGVVQ--LDCSIGYIYVDHLSRIDISFLLDVSSLSRAEED 741
+ L+ ++CE + + S ++ L C++ + + + + S +
Sbjct: 832 VEMLKPHSQIPVSCEELPEESRLLSRALSCNVSSPIFKAGHSVALQMMFNTLVNSSWGDS 891
Query: 742 LSITVHATCENEEEMDNLKHSRVTVAIPLKYEVKLTVHGFVNPTSFVYGSNDENEPETCM 801
+ + + TC NE+ D L+ + T IP+ Y + + + + T +Y S P+
Sbjct: 892 VELHANVTCNNEDS-DLLEDNSATTIIPILYPINILIQDQEDST--LYVSFTPKGPKIHQ 948
Query: 802 VEKMNLTFHVINTGNSMAPNVSVEIMVPNSFSPQTDKLFNILDVQTTTG-ECHFENYQRV 860
V+ M + + P + + VP P + + VQ CH+E+
Sbjct: 949 VKHMYQVRIQPSIHDHNIPTLEAVVGVPQP--PSEGPITHQWSVQMEPPVPCHYED---- 1002
Query: 861 CALEQQKSAMQTLKGIVRFLSKTDKRLLYCIKADPHCLNFLCNFGKMESGKEASVHIQLE 920
LE+ A + F R ++ + L G++E+ S+
Sbjct: 1003 --LERLPDAAEPCLPGALFRCPVVFRQEILVQV----IGTLELVGEIEASSMFSLC---- 1052
Query: 921 GRPSILEMDETSALKFEIRATGFPEPNPRVIELNKDENVAHVLLE-GLHHQRPKRYFTIV 979
S L + S+ F + + + ++A V+++ + +++ Y ++
Sbjct: 1053 ---SSLSISFNSSKHFHLYGS--------------NASLAQVVMKVDVVYEKQMLYLYVL 1095
Query: 980 IISSSLLLGLIVLLLISYVMWKAGFFKRQYKSILQ 1014
S + GL++LLLI V++K GFFKR K ++
Sbjct: 1096 ----SGIGGLLLLLLIFIVLYKVGFFKRNLKEKME 1126
>gi|148728188 integrin, alpha E precursor [Homo sapiens]
Length = 1179
Score = 187 bits (476), Expect = 3e-47
Identities = 213/846 (25%), Positives = 369/846 (43%), Gaps = 132/846 (15%)
Query: 211 IVMGAPGSSYWTGSLFVYNITTNKYKAFLDK------QNQVKFGSYLGYSVGAGHFRSQH 264
+++GA G+ W+G +Y+ T ++ FL++ + SYLGY+V H
Sbjct: 416 VLLGAVGAFDWSGGALLYD-TRSRRGRFLNQTAAAAADAEAAQYSYLGYAVAVLH--KTC 472
Query: 265 TTEVVGGAPQHEQIGKAYIFSIDEKELNILHEMKGKKLGSYFGASVCAVDLNADGFSD-L 323
+ + GAP+++ G + + +E + L ++G+++GSYFG+ +C VD++ DG +D L
Sbjct: 473 SLSYIAGAPRYKHHGAVFELQKEGREASFLPVLEGEQMGSYFGSELCPVDIDMDGSTDFL 532
Query: 324 LVGAPMQSTIREEGRVFVY-INSGSGAVMNAMETNLVGSDKYA-ARFGESIVNLGDIDND 381
LV AP EEGRV+VY ++ G+ ++ L G + ARFG ++ +GD+ D
Sbjct: 533 LVAAPFYHVHGEEGRVYVYRLSEQDGSF--SLARILSGHPGFTNARFGFAMAAMGDLSQD 590
Query: 382 GFEDVAIGAPQE----DDLQ--GAIYIYNGRADGISSTFSQRIEGLQISKSLSMFGQSIS 435
DVAIGAP E DD G++YIYNG DG+S++ SQRI ++ L FG S++
Sbjct: 591 KLTDVAIGAPLEGFGADDGASFGSVYIYNGHWDGLSASPSQRIRASTVAPGLQYFGMSMA 650
Query: 436 GQIDADNNGYVDVAVGAFRSDSAVLLRTRPVVIVDASLSHPESVNRTKFDCVENGWPSVC 495
G D +G D+ VG AV+ R+RPVV + S++ S F+ V
Sbjct: 651 GGFDISGDGLADITVGTL--GQAVVFRSRPVVRLKVSMAFTPSALPIGFNGV-------- 700
Query: 496 IDLTLCF---SYKGKEVPGYIVLFYNMSLDVN------RKAESPPRFYFS-----SNGTS 541
+++ LCF S G N +LDV+ R S R S+G+
Sbjct: 701 VNVRLCFEISSVTTASESGLREALLNFTLDVDVGKQRRRLQCSDVRSCLGCLREWSSGSQ 760
Query: 542 DVITGSIQVSSREANCRTHQAFMRKDVRDILTPIQIEAAYHLGPHVISKRSTEEFPPLQP 601
+ + + E F V+ + +Q P I R TE F
Sbjct: 761 --LCEDLLLMPTEGELCEEDCFSNASVK-VSYQLQTPEGQTDHPQPILDRYTEPF----A 813
Query: 602 ILQQKKEKDIMKKTINFARFCAHENCSADLQVSAKIGFLKPHENKTYLAVGSMKTLMLNV 661
I Q EK K C A+LQ++ + ++ L VG K L LN+
Sbjct: 814 IFQLPYEKACKNKLF----------CVAELQLATTV-------SQQELVVGLTKELTLNI 856
Query: 662 SLFNAGDDAYETTLHVKLPVGLYFIKILELEEKQINCEVTDN-SGVVQLDCSIGYIYVDH 720
+L N+G+D+Y T++ + P L ++ + I C+ + V+ ++C IG+ +
Sbjct: 857 NLTNSGEDSYMTSMALNYPRNLQLKRMQKPPSPNIQCDDPQPVASVLIMNCRIGHPVLKR 916
Query: 721 LS-RIDISFLLDVSSLSRAEEDLSITVHATCENEEEMDNLKHSRVTVAIPLKYEVKLTVH 779
S + + + L+ ++ D+++TV N E +L + T+ H
Sbjct: 917 SSAHVSVVWQLEENAFPNRTADITVTV----TNSNERRSLANETHTLQFR---------H 963
Query: 780 GFV---NPTSFVYGSNDENEPETCMVEKMNLTFHVINTGNSMAPNVSVEIMVPNSF-SPQ 835
GFV + S +Y + + + FHV + N ++I VP Q
Sbjct: 964 GFVAVLSKPSIMYVNTGQG-----LSHHKEFLFHV-HGENLFGAEYQLQICVPTKLRGLQ 1017
Query: 836 TDKLFNILDVQTTTGECHFENYQRVCALEQQKS-AMQTLKGIVRFLSKTDKRLLYCIKAD 894
+ + Q +T VC Q+++ A +++ + + S +
Sbjct: 1018 VVAVKKLTRTQAST----------VCTWSQERACAYSSVQHVEEWHSVS----------- 1056
Query: 895 PHCLNFLCNFGKMESGKEASVHIQLEGRPSILEMDETSALKFEIRATGFPEPNPRVIE-L 953
C + + I + +L+ D T E++ G N + E L
Sbjct: 1057 -------CVIASDKENVTVAAEISWDHSEELLK-DVT-----ELQILGEISFNKSLYEGL 1103
Query: 954 NKDENVAHVLLEGLHHQRPKRYFTIVIISSSLLLGLIVLLLISYVMWKAGFFKRQYKSIL 1013
N + + + + L ++ Y ++ II + GL+VL++I +++K GFFKR+Y+ +
Sbjct: 1104 NAENHRTKITVVFLKDEK---YHSLPIIIKGSVGGLLVLIVILVILFKCGFFKRKYQQLN 1160
Query: 1014 QEENRR 1019
E R+
Sbjct: 1161 LESIRK 1166
>gi|29171717 glycosylphosphatidylinositol specific phospholipase D1
isoform 1 precursor [Homo sapiens]
Length = 840
Score = 52.0 bits (123), Expect = 3e-06
Identities = 50/214 (23%), Positives = 92/214 (42%), Gaps = 25/214 (11%)
Query: 251 LGYSVGAGHFRSQHTTEVVGGAPQ-----HEQIGKAYIF-----SIDEKELNILHE---- 296
LG+++ + ++V GAP H IG+ Y+ + +L++ E
Sbjct: 381 LGWAMTSADLNQDGHGDLVVGAPGYSRPGHIHIGRVYLIYGNDLGLPPVDLDLDKEAHRI 440
Query: 297 MKGKKLGSYFGASVCAVDLNADGFSDLLVGAPM--QSTIREEGRVFVYINSGSGAVMNAM 354
++G + FG+++ +D N DG DL VGAP + +G V+VY S G + ++
Sbjct: 441 LEGFQPSGRFGSALAVLDFNVDGVPDLAVGAPSVGSEQLTYKGAVYVYFGSKQGGMSSSP 500
Query: 355 ETNLVGSDKYAARFGESIVNLGDIDNDGFEDVAIGAP------QEDDLQGAIYIYNGRAD 408
+ D Y G +++ D++ D D+ IG+P ++ + A Y +D
Sbjct: 501 NITISCQDIY-CNLGWTLL-AADVNGDSEPDLVIGSPFAPGGGKQKGIVAAFYSGPSLSD 558
Query: 409 GISSTFSQRIEGLQISKSLSMFGQSISGQIDADN 442
++ + S FG S+ G + DN
Sbjct: 559 KEKLNVEAANWTVRGEEDFSWFGYSLHG-VTVDN 591
Score = 38.5 bits (88), Expect = 0.033
Identities = 46/200 (23%), Positives = 83/200 (41%), Gaps = 48/200 (24%)
Query: 251 LGYSVGAGHFRSQHTTEVV--GGAPQHEQIGKA---------------YIFSIDEKELNI 293
LG S+ +GH T + V GAP ++ + K Y + D + L +
Sbjct: 647 LGTSLSSGHVLMNGTLKQVLLVGAPTYDDVSKVAFLTVTLHQGGATRMYALTSDAQPL-L 705
Query: 294 LHEMKGKKLGSYFGASVCAVDLNADGFSDLLVGAPMQSTI-------REEGRVFVYINSG 346
L G + S FG + DL+ DG ++++ AP++ E+GRV+VY +G
Sbjct: 706 LSTFSGDRRFSRFGGVLHLSDLDDDGLDEIIMAAPLRIADVTSGLIGGEDGRVYVY--NG 763
Query: 347 SGAVMNAMETN---------------LVGSDKYAARFGESIVNLGDIDNDGFEDVAIGAP 391
+ M ++ S + ++RFG S++ + + V I A
Sbjct: 764 KETTLGDMTGKCKSWITPCPEEKAQYVLISPEASSRFGSSLIT---VRSKAKNQVVIAAG 820
Query: 392 QED---DLQGAIYIYNGRAD 408
+ L GA+++Y+ +D
Sbjct: 821 RSSLGARLSGALHVYSLGSD 840
>gi|239751058 PREDICTED: hypothetical protein XP_002347690 [Homo
sapiens]
Length = 462
Score = 48.5 bits (114), Expect = 3e-05
Identities = 43/186 (23%), Positives = 73/186 (39%), Gaps = 11/186 (5%)
Query: 625 ENCSADLQVSAKIGFLKPHENKTYLAVGSMKTLMLNVSLFNAGDDAYETTLHVKLPVGLY 684
+NC AD +G L VGS L V ++N G+D+Y TT+ P GL
Sbjct: 18 KNCGADHICQDNLGISFSFPGLKSLLVGSNLELNAEVMVWNDGEDSYGTTITFSHPAGLS 77
Query: 685 FIKILE------LEEKQINCE--VTDNSGVVQLDCSIGYIYVDHLSRIDISFLLDVSSLS 736
+ + E L + C+ + G C I ++ ++I DVS +
Sbjct: 78 YRYVAEGQKQGQLRSLHLTCDSAPVGSQGTWSTSCRINHLIFRGGAQITFLATFDVSPKA 137
Query: 737 RAEEDLSITVHATCENEEEMDNLKHSRVTVAIPLKYEVKLTVHGFVNPTSFV-YGSNDEN 795
+ L +T + + EN + + +P+KY V V T ++ + ++E
Sbjct: 138 VLGDRLLLTANVSSEN--NTPRTSKTTFQLELPVKYAVYTVVSSHEQFTKYLNFSESEEK 195
Query: 796 EPETCM 801
E M
Sbjct: 196 ESHVAM 201
Score = 43.1 bits (100), Expect = 0.001
Identities = 19/38 (50%), Positives = 29/38 (76%)
Query: 980 IISSSLLLGLIVLLLISYVMWKAGFFKRQYKSILQEEN 1017
+I S + GL++L LI+ V++K GFFKRQYK +++E N
Sbjct: 407 LIVGSSIGGLLLLALITAVLYKVGFFKRQYKEMMEEAN 444
>gi|126032348 hect domain and RLD 2 [Homo sapiens]
Length = 4834
Score = 31.6 bits (70), Expect = 4.0
Identities = 30/114 (26%), Positives = 50/114 (43%), Gaps = 11/114 (9%)
Query: 691 LEEKQINCEVTDNSGVVQLDCSIGYIYVD------HLSRID--ISFLLDVSSLSRAEEDL 742
+E K IN +D + + DC+ + Y++ S ID I L+ + + EEDL
Sbjct: 2861 IELKTININPSDTTVPLLNDCTEYHRYIEIAIKQCRSSGIDCKIHGLILLGRIRAEEEDL 2920
Query: 743 SITVHATCENEEEMDNLKHSRVTVAIPLKYEVKLTVHGFVNPTSFVYGSNDENE 796
+ +NEEE D +S + K L + FV+G ND+++
Sbjct: 2921 AAVPFLASDNEEEEDEKGNSGSLIR---KKAAGLESAATIRTKVFVWGLNDKDQ 2971
>gi|156938343 talin 2 [Homo sapiens]
Length = 2542
Score = 30.4 bits (67), Expect = 9.0
Identities = 20/69 (28%), Positives = 32/69 (46%), Gaps = 14/69 (20%)
Query: 578 EAAYHLGPHVISKRST-----EEFPPLQPILQQKKEKDIMKKTINFARFCAHENCSADLQ 632
+A GPHV K +EF P + I Q+ EK I ++ H+NC +
Sbjct: 244 QAQIQFGPHVEHKHKPGFLDLKEFLPKEYIKQRGAEKRIFQE---------HKNCGEMSE 294
Query: 633 VSAKIGFLK 641
+ AK+ ++K
Sbjct: 295 IEAKVKYVK 303
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.135 0.403
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 40,582,376
Number of Sequences: 37866
Number of extensions: 1884013
Number of successful extensions: 4107
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 28
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 3716
Number of HSP's gapped (non-prelim): 83
length of query: 1032
length of database: 18,247,518
effective HSP length: 112
effective length of query: 920
effective length of database: 14,006,526
effective search space: 12886003920
effective search space used: 12886003920
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.